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If you are looking for a last-minute gift for a friend or loved one, Austin Pets Alive! has the paw-fect gift idea for the animal lover in your life.
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If you are looking for a last-minute gift for a friend or loved one, Austin Pets Alive! has the paw-fect gift idea for the animal lover in your life.
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For dog lovers, the prospect of a dog longevity drug sounds fantastic. Who doesn’t want their furry friends to live longer, healthier lives?
Recent developments from a San Francisco-based biotech company, Loyal, bring this dream closer to reality. They’ve announced an anti-aging drug for dogs that has cleared its first hurdle for FDA approval. This marks a pivotal moment in veterinary medicine, as it’s the first time the FDA has shown openness to endorsing longevity drugs for pets.
Loyal’s groundbreaking drug, LOY-001, targets a growth and metabolism hormone called IGF-1. This hormone, linked with size, appears in higher levels in larger dogs and lower in smaller ones. Studies on other species suggest inhibiting IGF-1 can increase lifespans. LOY-001 is aimed at healthy dogs over seven years old and weighing more than 40 pounds. Administered every three to six months by a vet, it holds the potential to slow down the aging process in dogs.
Parallel to this, Loyal is developing LOY-003, a daily pill form of the treatment. CEO Celine Halioua emphasizes that they’re not creating immortal dogs. The goal is to slow their rate of aging, thus maintaining a healthier state for a longer period.
As promising as these developments are, they raise significant ethical questions, particularly concerning the quality of extended life for these animals. Veterinarian Kate Creevy, involved in a similar trial for an anti-aging drug called rapamycin, stresses the importance of ensuring that any extended lifespan is accompanied by good health and quality of life.
Moreover, the human manipulation of dogs through selective breeding, which may have contributed to accelerated aging in larger breeds, underlines the ethical complexities in altering canine aging processes.
Loyal plans to start a large clinical trial for LOY-001 with around 1,000 large and giant dogs by either 2024 or 2025. The ultimate aim is to have a market-ready product by 2026. This trial not only represents a major step in veterinary medicine but also opens doors to understanding aging in more complex organisms like humans.
The success of Loyal’s drug could potentially revolutionize how we approach canine health and aging. It offers a glimpse into a future where our canine companions can enjoy longer, healthier lives alongside us. However, it’s crucial to balance this scientific advancement with ethical considerations to ensure the well-being of these beloved animals.
Source: “A New Drug That Could Extend Dogs’ Lives Inches Closer to Approval” — Smithsonian Magazine
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WTF
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24 pets
facing euthanasia are arriving at APA! now as their originating shelter
was presented with a potential eviction. The 90+ remaining animals in
the No Kill shelter hold the same fate if they can’t be moved to other
places.
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We love and consider them family, so as they age we want to help our little loves. As they age, our dogs often suffer a decline in functioning and can get sick more often. Because there is almost nothing sadder than a dog that’s feeling sick, you can give your dog hemp seed oil full of vitamin E and vitamin A to help their immune system fight any chemicals, drugs, pesticides and toxins that your dog may pick up in its day-to-day life.
RELATED: Fireworks And Pets, Can Marijuana Or CBD Help
Also, medical research has given some hope to older dogs. A study from the College of Veterinary Medicine at Cornell University revealed hemp oil can help aging dogs suffering from joint pain.
According to the study, a hemp-based medicine developed by ElleVet Sciences is “efficacious for pain in dogs with osteoarthritis, chronic joint pain and geriatric pain and soreness; with dramatic beneficial effects in our more geriatric patients.” The first-of-its-kind study took eight months to complete and examined how ElleVet’s soft chews metabolized and how it relieved joint pain in canines.
RELATED: Science Says Medical Marijuana Improves Quality Of Life
Joseph Wakshlag, associate professor of Cornell University’s College of Veterinary Medicine presented the findings of the first pharmacokinetic study and clinical trial on the use of cannabinoids to treat dogs with osteoarthritis and multi-joint pain at the Veterinary Meeting & Expo. The university partnered with ElleVet Sciences to conduct this double-blind, placebo-controlled study.
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Terry Hacienda
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Finding a doggy friend for your fur baby is not always easy. Some dogs can’t stand the sight of another dog, while others need time to build a friendship. But once a dog bond is formed, good luck ever separating them again.
A Pomeranian named Smudge who lives in New York City has a best friend who shall not be named. Well, she is named. She’s Lola. But Smudge’s owner has to be careful when to say Lola because Smudge will immediately start looking for her.
In a December 3 TikTok clip, which was posted to the account @mitchellramazon, Smudge’s owner asked if he wanted to go to Lola’s house. His response was a full-on sprint in the direction of her house.
The way the two greeted each other is a “love story” for the ages that has users obsessed, bringing in nearly 800,000 views and 124,400 likes.
This Pomeranian’s tiny legs weren’t going to slow him down from seeing Lola. The owner had to run down the leaf-covered NYC sidewalks to keep up with Smudge.
The only thing better about Smudge’s excitement to see Lola was how they greeted each other. So many tail wags, crying, and tiny, joyful hops.
“I was not expecting them to be the exact perfect size for each other,” commented a viewer. Another added: “The way they ‘hugged’ each other.”
Luckily, these two lovers get to see each other often. When someone wrote that they hoped Smudge and Lola get regular play dates, the owner responded by saying every week.
Newsweek reached out via TikTok for additional information.
Owners will often joke about the fact their dog has a furry best friend, and while some might not believe it, doggy BFFs are real.
Aside from dogs getting out all their energy while playing with a best friend, Pet MD reported there are other health benefits involved. Dog besties can reduce stress and provide comfort and safety. They are more tolerant of their friend’s presence, oftentimes showing less aggressive behavior.
You will notice when your dog has a best friend or close companion, when they start to stay in closer proximity with the other animal, the Pet MD article continues. They will ignore other dogs to play with their best friend. Plus, they’ll likely share toys, a bed, a water bowl, and space, although, not always.
Do you have funny and adorable videos or pictures of your pet you want to share? Send them to life@newsweek.com with some details about your best friend and they could appear in our Pet of the Week lineup.
Newsweek is committed to challenging conventional wisdom and finding connections in the search for common ground.
Newsweek is committed to challenging conventional wisdom and finding connections in the search for common ground.
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SHENZHEN, China, November 30, 2023 (Newswire.com)
–
UBPet proudly launches the C20 Smart Cat Litter Box, setting new standards in pet care innovation. This automatic self-cleaning litter box is a game-changer, providing top-notch feline care with its cutting-edge waste removal system and advanced odor control.
Designed with intelligence and safety in mind, the C20 offers an elegant solution for every cat owner’s challenges. Its thoughtful and sleek design effortlessly blends into any home while creating a clean, odor-free environment for both cats and owners.
Unlike conventional litter boxes, the C20 boasts a spacious entrance and a generous capacity, catering to cats’ natural desire for freedom of movement. Its low entry height makes it ideal for older cats, short-legged breeds, and kittens alike.
Safety is paramount, and the C20’s integrated design ensures absolute pet safety. The waste container and roller move together during cleaning, eliminating any risk of entrapment or injury to your furry friend.
This litter box features a Double-Layer Anti-Stick Protection system, using silicone and highly durable fabric to prevent sticking and ensure long-lasting durability. It also incorporates a dual odor control mechanism, employing aromatic deodorizing blocks to break down odors and neutralize ammonia-based compounds.
“At UBPet, we prioritize pets’ well-being above all. The C20 Smart Cat Litter Box is our commitment to creating a safe haven for cats, ensuring their safety and comfort at all times,” said Bo Zhang, the Manager of UBPet.
The C20 revolutionizes litter box maintenance with its one-touch automatic cleaning feature and easy litter disposal. It allows the use of standard plastic garbage bags for waste disposal, making cleanup effortless.
Furthermore, this smart litter box offers remote control via an app, facilitating automatic and scheduled cleaning, custom settings, and health monitoring for multi-cat households.
The C20 Smart Cat Litter Box is the epitome of intelligent pet care, combining safety, comfort, and smart design. Its modern aesthetic complements any home, providing convenience and style while offering a superior experience for both cats and owners.
Join us and embrace the future of feline care with exclusive deals and discounts for early adopters. Learn more here: https://www.indiegogo.com/projects/ubpet-c20-smart-spacious-cat-litter-box/x/35652123#/
Source: UBPet
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Dogs are the number one pet with over 25% of the global population having owned a dog at some point. In fact Argentina (82%), Mexico (81%) and Brazil (76%) have the highest rates of pet ownership – with dogs being at the top of the list. Bet did you know data has shown it seems women who share their bed with a dog get the best sleep.
There are multiple benefits not only. do they provide companionship, they provide other benefits. Dogs keep you active, help you become calmer and make you more social. The improve the lives of kids and older individuals. A portion of pet owners sleep with their pets. Exploring the realm of sleep and pet owners, researchers to discover the data if it has effects on humans.
RELATED: People Who Use Weed Also Do More Of Another Fun Thing
Scientists from Canisius College in Buffalo, New York found the answer, publishing their findings in Anthrozoös, a journal studying human-animal interactions. While it’s known sleeping next to humans provides some positive and negative effects, much less is known about the benefits and hazards of sleeping with your pet. Until now.
The researchers surveyed over 962 women who reside in the U.S., gathering data on their sleeping patterns and partners, specifically looking for information regarding the relationship between pet ownership and sleep. More than half, 57 percent, of participants slept with humans, 55 percent of them with dogs, and 31 percent of them with cats. Dog owners demonstrated earlier bed times and earlier wake up times, surprising everyone but dog owners, because we’ve all been awoken by a stray paw in the face just before your alarm clock rings.
Related: Science: You’re More Likely To Land A Date If You Have A Dog
Compared to human partners, dogs provided more security and comfort, and also disturbed women less as they slept. Sorry boyfriends and girlfriends, dogs are cuter and also quiet. Cats got the worst end of the deal, with the study finding them just as disruptive as human partners and less comforting than any other companion.
Science now supports the fact that there are no better cuddlers than a sleepy dog. Dog owners have known this all along, now they just have the chance to show it off to their germaphobe friends, proving to them that there’s a reason why they’re always covered in hair.
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Maria Loreto
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A California biotech company that’s pioneering a drug aiming to extend the lifespan of dogs said it cleared a vital hurdle, as the medication gained a portion of conditional approval by the U.S. Food and Drug Administration (FDA).
Loyal, a San Francisco-based company founded in 2020, has been researching ways to increase the lifespan of dogs, particularly large and giant breeds, the biotech company said in a statement on Tuesday, which added that “today’s announcement shows the FDA believes Loyal’s approach is valid.”
The FDA Center for Veterinary Medicine has approved the “reasonable expectation of effectiveness” section of Loyal’s conditional approval application for LOY-001, the name of the drug the company is developing to both extend the lifespan of big dogs and maintain their quality of life, Loyal spokesman Tim Smith said in a statement.
While Loyal did not specify in the statement how long the drug could extend the lives of large canine companions, the company says on its website that the drug will be a “long-acting injectable” administered by a veterinarian every three to six months. At the time of publication, the estimated cost of the drug had not been released.
Smith said the FDA’s expanded conditional approval is an “accelerated pathway” for the drug, which Loyal estimates will be available in 2026.
“Today’s milestone is a crucial part of Loyal’s application for conditional approval,” Smith said. “It means the FDA agrees LOY-001 has a reasonable expectation of effectiveness and, once the FDA approves Loyal’s manufacturing and safety data packages, Loyal can market the drug for lifespan extension in the target canine population. Conditional approval lasts for up to five years, during which time Loyal will collect the remaining effectiveness data and apply for full approval.”
A spokesperson for the FDA told Newsweek on Tuesday that the agency could not comment on applications that are in progress.
The FDA Center for Veterinary Medicine has reviewed Loyal’s findings, which included data, results and scientific arguments, and determined that the information provides “reasonable expectation of the drug’s effectiveness to extend canine lifespan and healthspan,” Smith said in the statement.
The drug still has to successfully complete its “manufacturing and safety” sections of its application before it receives conditional approval, which will allow the biotech company to market LOY-001 for “large-dog lifespan extension,” he said.
Loyal CEO Celine Halioua, in a statement sent to Newsweek on Tuesday, described the FDA’s nod of approval on the section of the application as a “milestone.”
“Loyal was founded with the ambitious goal of developing the first drugs to extend healthy lifespan in dogs,” Halioua said. “This milestone is the result of years of careful work by the team. We’ll continue to work just as diligently to bring this and our other longevity programs through to FDA approval.”
Selectively breeding dogs has caused elevated levels of the growth-promoting hormone IGF-1, which is believed to reduce their lifespan, according to Loyal, which says that big dogs have vastly more of the hormone than small pooches, with the latter known to live nearly twice as long.
“LOY-001 works by reducing IGF-1 in adult dogs to increase lifespan,” Smith said.
The goal of LOY-001 is to treat age-associated diseases by “targeting mechanisms” of aging to prevent or delay the onset of those diseases rather than waiting for the animals to get sick before administering treatment.
Loyal said part of the research included in the FDA application was the results of a “large observational study” involving 452 dogs of 84 different breeds from ages 2 to 18. The study, according to Loyal, showed “LOY-001’s ability to reduce levels of key biomarker IGF-1 and the beneficial impact on functional outcomes in dogs.”
Despite the FDA’s “milestone” ruling on Tuesday, some experts and animal advocates are leery that the drug can do what it claims, fearing it’ll extend animals’ suffering instead, according to a report by The New York Times. The outlet reported that experts say more testing and clinical studies have to be completed before LOY-001 is proven to extend the life of dogs.
Newsweek is committed to challenging conventional wisdom and finding connections in the search for common ground.
Newsweek is committed to challenging conventional wisdom and finding connections in the search for common ground.
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For many pet lovers, turning their passion for animals into a profitable side hustle is a dream come true. It helps that the pet industry continues to flourish, with Americans spending over $136 billion on their pets in 2022, according to the American Pet Products Association.
If you’re considering diving into the world of entrepreneurship with a side hustle, franchising in the pet industry could be a “paw-some” choice.
But with every business-related decision, make sure to do your due diligence in franchise research and reflect on what may be the best possible business opportunity for you. To get started, here are five pet-related franchises to consider, ideal for combining your entrepreneurial initiative with your love for animals.
We don’t always think about the stinky side of pet ownership—but believe it or not: it’s a side in which you can use your entrepreneurial spirit. DoodyCalls is a mobile pet-waste management company that offers a low overhead, passive income opportunity that can be managed at any time of the day.
This allows franchisees to cater to a wide range of clients, providing a much-needed solution for pet owners who love their dogs but dislike or are not able to clean up after them. Aided by Authority Brands, DoodyCalls has the resources needed to own a business, including training to not only prepare franchise owners but also support franchise owners year-round.
If you have a knack for making pets look their best and you want to be an entrepreneur on the go, then a mobile pet grooming franchise like Aussie Pet Mobile may be the perfect fit.
Aussie Pet Mobile prides itself on providing flexible, quality and expert grooming care services to their clients—and as a franchisee you will be joining the largest brand in mobile pet grooming. Franchisees are equipped with a protected territory, ample training and support, the grooming van and all you need to scale your business.
Related: 10 Tips to Go From Employee to Boss, From Franchisees Who Did It
Trying to stay away from costly boarding or doggy day care facilities? Then Zoom Room could be a good fit. Zoom Room is an elite indoor dog training franchise that focuses on expert training, socialization and selective pet product sales.
What sets Zoom Room apart as a franchise, however, is its focus on low startup and ongoing overhead costs, making it ideal as a side hustle.
Zoom Room requires a smaller facility footprint than other pet-related franchises, and since owners accompany their dogs at all times (at the end of the day, you are training people, not just dogs), there may be less liability associated with your venture.
You may not initially associate a pet supplies store with being a side hustle. In fact, pet supplies stores will probably involve a heavier initial investment than a mobile grooming business would. But once you get a Pet Supplies Plus franchise off the ground, you will reap the benefits as if it were a side hustle. Combine your passion for animals with a full service supply store with proprietary products, a streamlined shopping experience and a grooming facility to build out your franchising aspirations. Pet Supplies Plus is a proven, award-winning brand that wants to set its franchisees up for success from the get-go.
Are you a foodie and an animal lover? You can combine those two passions with a Woof Gang Bakery & Grooming franchise. At Woof Gang Bakery & Grooming, a simple pet grooming experience is transformed with a large selection of treatments accompanied by high-end tasty treats.
Woof Gange Bakery & Grooming will set you up for success with local and national marketing support, pre-opening support (like creating a business plan) and on-the-job training.
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Clarissa Buch Zilberman
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The power of social media came through for a 17-pound dog who was known as an “a******” living in a Texas-based animal shelter.
The Humane Society of Wichita County shared in a November 16 Facebook post that a small dog named Eddie packed a punch and despite his small stature, he could take on a Rottweiler.
“If Eddie had an accent, he would sound like he’s from the Bronx, wearing a wife beater t-shirt and a tattoo that says MOM on his arm,” the post reads. “If you got into a bar fight, Eddie would back you up and take on all 5 guys, put his cigarette out on their forehead and not spilling a drop of his beer while doing it.”
The sarcastic embellishments about Eddie quickly went viral, ultimately landing him a forever home in just a few hours.
Director Cheryl Heineken told Newsweek that Eddie does not get along with other dogs. Shelter employees had to pull Eddie off two other dogs. But, luckily, he never showed aggression toward people. In fact, this 1-year-old dachshund mix actually does very well with people.
Heineken said it is hard to place dogs in their homes when a dog only gets along with people. Knowing that, she said had to come up with something to make him stand out. Something to make up adoptable.
And what better way to do that than to challenge potential adopters by asking, “So, if you think you are man enough to adopt him, please be our guest. We want Eddit out of here because he scares our big dogs.”
In less than eight hours from the original post, the Humane Society posted a new picture of Eddie with his forever family. Eddie instantly melted into the family’s 15-year-old daughter.
The post gathered attention from around the world including Canada and Australia, Heineken said. It was shared over 79,000 times. Not only did it give people a good chuckle, but users appreciated the honesty.
“This is the best thing on the internet today,” wrote a Facebook user.
Another one added: “I feel like whoever wrote Eddie’s bio could get every shelter and rescue dog in America adopted by writing theirs.”
Fans who fell in love with Eddie’s sassy ways can still follow him along as his family started his own Facebook page—Ahole Eddie. The now-famous dog has over 31,000 followers in less than a week of the page starting.
And it looks like Ahole Eddie is putting his best paw forward, replying to requests from followers for an Ahole Eddie Wish List (“Hooman said not to wish for beer and cigarettes because I need to support my own bad habits.”) by putting together a modest list and asking others to donate to shelters.
Social media has spread its fingers into virtually every part of a person’s life. And now, thanks to the connection and constant sharing, animal shelters are benefiting from social media as well.
A 2018 survey from the American Society for the Prevention of Cruelty to Animals found there was an increase in awareness and adoptions thanks to the positive impacts of social media.
Of the 800 shelters surveyed, 86 percent saw an increase in general awareness about their organization, 66 percent had an increase in overall animal adoptions, and 55 percent had increased adoption rates for harder-to-place animals like senior pets or those with medical issues.
Do you have funny and adorable videos or pictures of your pet you want to share? Send them to life@newsweek.com with some details about your best friend and they could appear in our Pet of the Week lineup.
Newsweek is committed to challenging conventional wisdom and finding connections in the search for common ground.
Newsweek is committed to challenging conventional wisdom and finding connections in the search for common ground.
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Veterinary laboratories in several states are investigating an unusual respiratory illness in dogs, and encouraging people to take basic precautions to keep their pets healthy as veterinarians try to pin down what’s making the animals sick.
Oregon, Colorado and New Hampshire are among the states that have seen cases of the illness, which has caused lasting respiratory disease and pneumonia and does not respond to antibiotics. Symptoms of respiratory illness in dogs include coughing, sneezing, nasal or eye discharge and lethargy. Some cases of the pneunomia progress quickly, making dogs very sick within 24 to 36 hours.
The Oregon Department of Agriculture has documented more than 200 cases of the disease since mid-August. It has encouraged pet owners to contact their vet if their dog is sick and told state veterinarians to report cases as soon as possible. The agency is working with state researchers and the U.S. Department of Agriculture’s National Veterinary Services Laboratory to find out what is causing the illnesses.
Dogs have died, said Kurt Williams, director of the Oregon Veterinary Diagnostic Laboratory at Oregon State University. But without a clear way to define the disease or test for it, he said it’s hard to put a number on how many died from a severe form of the infection.
Williams had a simple message for dog owners: “Don’t panic.” He also said dog owners should make sure that their pets are up to date on vaccines, including those that protect against various respiratory illnesses.
Labs across the country have been sharing their findings as they try to pinpoint the culprit.
David Needle, senior veterinary pathologist at the University of New Hampshire’s New Hampshire Veterinary Diagnostic Laboratory, has been investigating the mysterious disease for almost a year.
His lab and colleagues at the university’s Hubbard Center for Genome Research have looked at samples from dogs in Rhode Island, New Hampshire and Massachusetts and more will be coming from Oregon, Colorado and possibly other states.
He said his team has not seen a large increase in dogs dying from the illness but still encouraged pet owners to “decrease contact with other dogs.”
The Associated Press Health and Science Department receives support from the Robert Wood Johnson Foundation. The AP is solely responsible for all content.
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