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Tag: longevity

  • What’s the Best Weight-Loss and Disease-Prevention Diet?  | NutritionFacts.org

    What’s the Best Weight-Loss and Disease-Prevention Diet?  | NutritionFacts.org

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    The most effective diet for weight loss may also be the most healthful.

    Why are vegetarian diets so effective in preventing and treating diabetes? Maybe it is because of the weight loss. As I discuss in my video The Best Diet for Weight Loss and Disease Prevention, those eating more plant-based tend to be significantly slimmer. That isn’t based on looking at a cross-section of the population either. You can perform an interventional trial and put it to the test in a randomized, controlled community-based trial of a whole food, plant-based diet.

    “The key difference between this trial [of plant-based nutrition] and other approaches to weight loss was that participants were informed to eat the WFPB [whole food, plant-based] diet ad libitum and to focus efforts on diet, rather than increasing exercise.” Ad libitum means they could eat as much as they want; there was no calorie counting or portion control. They just ate. It was about improving the quality of the food rather than restricting the quantity of food. In the study, the researchers had participants focus just on a diet rather than exercising more exercise because they wanted to isolate the effects of eating more healthfully.

    So, what happened? At the start of the study, the participants were, on average, obese at nearly 210 pounds (95 kg) with an average height of about 5’5” (165 cm). Three months into the trial, they were down about 18 pounds (8 kg)—without portion restrictions and eating all the healthy foods they wanted. At six months in, they were closer to 26 pounds (12 kg) lighter. You know how these weight-loss trials usually go, though. However, this wasn’t an institutional study where the participants were locked up and fed. In this trial, no meals were provided. The researchers just informed them about the benefits of plant-based eating and encouraged them to eat that way on their own, with their own families, and in their own homes, in their own communities. What you typically see in these “free-living” studies is weight loss at six months, with the weight creeping back or even getting worse by the end of a year. But, in this study, the participants were able to maintain that weight loss all year, as you can see below and at 1:57 in my video.

    What’s more, their cholesterol got better, too, but the claim to fame is that they “achieved greater weight loss at 6 and 12 months than any other trial that does not limit energy [caloric] intake or mandate regular exercise.” That’s worth repeating. A whole food, plant-based diet achieved the greatest weight loss ever recorded at 6 and 12 months compared to any other such intervention published in the medical literature. Now, obviously, with very low-calorie starvation diets, you can drop down to any weight. “However, medically supervised liquid ‘meal replacements’ are not intended for ongoing use”—obviously, they’re just short-term fixes—“and are associated with ‘high costs, high attrition rates, and a high probability of regaining 50% or more of lost weight in 1 to 2 years.’” In contrast, the whole point of whole food, plant-based nutrition is to maximize long-term health and longevity.

    What about low-carb diets? “Studies on the effects of low-carbohydrate diets have shown higher rates of all-cause mortality”—meaning a shorter lifespan—“decreased peripheral flow-mediated dilation [artery function], worsening of coronary artery disease, and increased rates of constipation, headache, halitosis [bad breath], muscle cramps, general weakness, and rash.”

    The point of weight loss is not to fit into a smaller casket. A whole food, plant-based diet is more effective than low-carb diets for weight loss and has the bonus of having all good side effects, such as decreasing the risk of diabetes beyond just weight loss.

    “The lower risk of type 2 diabetes among vegetarians may be explained in part by improved weight status (i.e., lower BMI). However, the lower risk also may be explained by higher amounts of ingested dietary fiber and plant protein, the absence of meat- and egg-derived protein and heme iron, and a lower intake of saturated fat. Most studies report the lowest risk of type 2 diabetes among individuals who adhere to vegan diets. This may be explained by the fact that vegans, in contrast to ovo- and lacto-ovo-vegetarians, do not ingest eggs. Two separate meta-analyses linked egg consumption with a higher risk of type 2 diabetes.”

    Maybe it’s eating lower on the food chain, thereby avoiding the highest levels of persistent organic pollutants, like dioxins, PCBs, and DDT in animal products. Those have been implicated as a diabetes risk factor. Or maybe it has to do with the gut microbiome. With all that fiber in a plant-based diet, it’s no surprise there would be fewer disease-causing bugs and more protective gut flora, which can lead to less inflammation throughout the body that “may be the key feature linking the vegan gut microbiota with protective health effects”—including the metabolic dysfunction you can see in type 2 diabetes.

    The multiplicity of benefits from eating plant-based can help with compliance and family buy-in. “Whereas a household that includes people who do not have diabetes may be unlikely to enthusiastically follow a ‘diabetic diet,’ a low-fat plant-based approach is not disease-specific and has been shown to improve other chronic conditions. While the patient [with diabetes] will likely see improvement in A1C [blood sugar control], a spouse suffering from constipation or high blood pressure may also see improvements, as may children with weight issues,” if you make healthy eating a family affair.

    This is just a taste of my New York Times best-selling book, How Not to Diet. (As with all of my books, all proceeds I received went to charity.) Watch the book trailer. You may also be interested in its companion, The How Not to Diet Cookbook.

    Check out my hour-long Evidence-Based Weight Loss lecture for more. 

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    Michael Greger M.D. FACLM

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  • How Women Can Prevent Dementia In Their 40s (& Beyond)

    How Women Can Prevent Dementia In Their 40s (& Beyond)

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    These reproductive hormones push neurons to bring glucose and make energy—thus, if your hormone levels are high, your brain energy is high. “But then what happens to testosterone is that it doesn’t quite decline that much over time; whereas for women, estrogens pretty much plummet when women go through menopause,” she explains. “If you think of these hormones as having some kind of superpowers for the brain, women lose the superpower around the time that menopause hits, right? And the brain is left a little more vulnerable.”

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  • What About Animal Protein and Vegetarians’ Stroke Risk?  | NutritionFacts.org

    What About Animal Protein and Vegetarians’ Stroke Risk?  | NutritionFacts.org

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    Might animal protein-induced increases in the cancer-promoting growth hormone IGF-1 help promote brain artery integrity? 

    In 2014, a study on stroke risk and dietary protein found that greater intake was associated with lower stroke risk and, further, that the animal protein appeared particularly protective. Might that help explain why, as shown in the graph below and at 0:31 in my video Vegetarians and Stroke Risk Factors: Animal Protein?, vegetarians were recently found to have a higher stroke rate than meat eaters?

    Animal protein consumption increases the levels of a cancer-promoting growth hormone in the body known as IGF-1, insulin-like growth factor 1, which “accelerates the progression of precancerous changes to invasive lesions.” High blood concentrations are associated with increased risks of breast, colorectal, lung, and prostate cancers, potentially explaining the association between dairy milk intake and prostate cancer risk, for example. However, there are also IGF-1 receptors on blood vessels, so perhaps IGF-1 promotes cancer and brain artery integrity.

    People who have strokes appear to have lower blood levels of IGF-1, but it could just be a consequence of the stroke rather than the cause. There weren’t any prospective studies over time until 2017 when researchers found that, indeed, higher IGF-1 levels were linked to a lower risk of stroke—but is it cause and effect? In mice, the answer seems to be yes, and in a petri dish, IGF-1 appears to boost the production of elastin, a stretchy protein that helps keep our arteries elastic. As you can see in the graph below and at 1:41 in my video, higher IGF-1 levels are associated with less artery stiffness, but people with acromegaly, like Andre the Giant, those with excessive levels of growth hormones like IGF-1, do not appear to have lower stroke rates, and a more recent study of dietary protein intake and risk of stroke that looked at a dozen studies of more than half a million people (compared to only seven studies with a quarter million in the previous analysis), found no association between dietary protein intake and the risk of stroke. If anything, dietary plant protein intake may decrease the risk of stroke. 

    However, those with high blood pressure who have low IGF-1 levels do appear to be at increased risk of developing atherosclerosis, which is the thickening of the artery walls leading up to the brain, but no such association was found in people with normal blood pressure. So, there may be “a cautionary lesson for vegans” here. Yes, a whole food, plant-based diet “can down-regulate IGF-1 activity” and may slow the human aging process, not to mention reduce the risk of some of the common cancers that plague the Western world. But, “perhaps the ‘take-home’ lesson should be that people who undertake to down-regulate IGF-1 activity [by cutting down on animal protein intake] as a pro-longevity measure should take particular care to control their blood pressure and preserve their cerebrovascular health [the health of the arteries in their brain] – in particular, they should keep salt intake relatively low while insuring an ample intake of potassium” to keep their blood pressures down. So, that means avoiding processed foods and avoiding added salt, and, in terms of potassium-rich foods, eating beans, sweet potatoes, and dark-green leafy vegetables. 

    Might this explain the higher stroke risk found among vegetarians? No—because dairy and egg whites are animal proteins, too. Only vegans have lower IGF-1 levels in both men and women, so low levels of IGF-1 can’t explain why higher rates of stroke were found in vegetarians. Then what is it? I think the best explanation for the mystery is something called homocysteine, which I cover next. 

    If you aren’t familiar with IGF-1, my videos Flashback Friday: Animal Protein Compared to Cigarette Smoking and How Not to Die from Cancer are good primers. 

    Beyond eating a plant-based diet, how else can we lower our blood pressure? Check out the chapter of hypertension in my book How Not to Die at your local public library. 

    This is the eighth video in a 12-part series on vegetarians’ stroke risk. If you missed any of the previous ones, check out the related posts below.

    Coming up, we turn to what I think is actually going on:

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    Michael Greger M.D. FACLM

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  • Bon Charge Labor Day Sale: Last Chance To Save 25%

    Bon Charge Labor Day Sale: Last Chance To Save 25%

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    If you’re still skeptical about the power of red light therapy, I get it. I was hesitant, too, before I used Bon Charge’s Red Light Face Mask for one month. During the 30-day experiment, my skin completely transformed to reveal a brighter, more even complexion—and it was easily the best thing I’ve done for my skin years.

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  • This One Habit Can Support Your Dog's Longevity, Says A Veterinarian

    This One Habit Can Support Your Dog's Longevity, Says A Veterinarian

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    Intermittent fasting (or feeding) can add years to your dog’s life.

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  • How To Increase Your Pet’s Longevity, From A Veterinarian

    How To Increase Your Pet’s Longevity, From A Veterinarian

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    The number of pet parents has exploded in the past couple of years, as people turned to furry four-legged friends to help with stress, anxiousness, and uncertainty. For many dog owners, pets provide companionship on long walks, plus unwavering comfort and cuddles—a distraction from the bad news, and a beacon of hope for tomorrow.

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  • Unbelievable facts

    Unbelievable facts

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    Men who marry after age 25 generally live longer than those who marry at a younger age.

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  • New Study On How Long To Work Out A Week For Health Span & Life Span

    New Study On How Long To Work Out A Week For Health Span & Life Span

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    mbg Health Contributor

    Jenny is a San Francisco-based mbg contributor, content designer, and climate & sustainability communications specialist. She is a graduate of the University of California Santa Barbara. An avid open-water swimmer, Jenny has worked for healthy living and nutrition brands like Sun Basket, Gather Around Nutrition, and Territory Foods.

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  • Blue Zones Founder Says Walking Is The Top Exercise For Longevity

    Blue Zones Founder Says Walking Is The Top Exercise For Longevity

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    Longevity has become nothing short of a buzzword, as more and more people strive for well-being into their later years. And by now, we know that several studies have linked regular exercise—even in the form of small daily movements—to a longer life.

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  • How Vitamin D Regulates The Role Of Dopamine In Brain Cells

    How Vitamin D Regulates The Role Of Dopamine In Brain Cells

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    It’s not clear exactly what causes schizophrenia, but we know that it’s associated with changes in the way the brain uses dopamine, and dopamine also plays a role in Parkinson’s disease, ADHD, and restless legs syndrome. It’s also possible to have low dopamine levels without a diagnosed brain disorder. As neuroscientist and psychiatrist Daniel Amen, M.D., explained previously to mbg, symptoms of low dopamine might look like: 

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  • Research Suggests Unresolved Anxiety Could Lead To This

    Research Suggests Unresolved Anxiety Could Lead To This

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    If you struggle with anxiety, you don’t need us to tell you that it can be incredibly difficult to manage. But according to new research published in the Journal of the American Geriatrics Society, unresolved anxiety could cause even more issues down the road. Here’s what they found.

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  • Social Prescriptions Are The Future: Here’s 5 You Should Know

    Social Prescriptions Are The Future: Here’s 5 You Should Know

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    “We sort of have our cultural picture of what loneliness is, you know, maybe an older person who’s isolated. Actually, loneliness refers to the absence of quality relationships, just as I mean, the cliché is true. You can be lonely in a crowd,” Hotz says.

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  • Is Your VO2 Max Low? Here’s 3 Signs It Could Be, From An Expert

    Is Your VO2 Max Low? Here’s 3 Signs It Could Be, From An Expert

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    Hannah Frye is the Assistant Beauty Editor at mindbodygreen. She has a B.S. in journalism and a minor in women’s, gender, and queer studies from California Polytechnic State University, San Luis Obispo. Hannah has written across lifestyle sections including health, wellness, sustainability, personal development, and more.

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  • No Link Between Light Drinking and Longer Life, Study Finds

    No Link Between Light Drinking and Longer Life, Study Finds

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    Research published Thursday offers a sobering rebuttal to the idea that booze can be life-extending. In a new review of the data, scientists failed to find high-quality evidence that people who drink light to moderate amounts of alcohol are likely to live longer than people who abstain from drinking. The findings suggest that there isn’t really a truly safe level of alcohol consumption.

    For many years, there’s been a steady drip of studies suggesting that light to moderate drinking can be beneficial to our longevity and health, particularly when it comes to our hearts. Other recent research is increasingly finding contradictory evidence, however, while some scientists have criticized the methodology of these rosier studies. 

    The sick abstainer effect

    One major criticism has revolved around people who quit drinking alcohol. Some abstainers rarely consumed alcohol during their lives, while others are former heavy drinkers who quit due to health issues caused by their alcohol use. Scientists run the risk of skewing comparisons between abstainers and moderate drinkers by including individuals who abstain due to health issues in the general group. Since those with health issues are likely to be sicker than average, this can unfairly favor moderate drinkers.

    Scientists from the University of Victoria in Canada tried to correct for this and other gaps in their newest review of the evidence, published Thursday in the Journal of Studies on Alcohol and Drugs.

    “Unlike past attempts, we focused on identifying and testing study characteristics that may bias estimates of mortality risk, providing a more robust analysis of the available data,” study author James Clay, a postdoctoral research fellow at the university’s Canadian Institute for Substance Use Research, told Gizmodo in an email.

    Controlling for bias

    Clay and his team looked at more than 100 studies that followed people’s health over time and included information on their reported level of drinking. When the team analyzed the data as a whole, they found a small association between a longer life and low-volume drinking (defined as anything between one drink a week and up to two drinks a day). They then divided the studies into those considered higher or lower quality research and analyzed them separately. Higher quality research, for example, included studies that excluded former drinkers from the abstainer group or started tracking people at a younger age. And when they only looked at the higher quality data, a different picture emerged.

    “Essentially, when we carefully controlled for potential biases, the supposed health benefits of low-volume alcohol consumption disappeared,” Clay explained.

    The team’s findings aren’t the first to question the idea of healthy drinking, even for our hearts. But according to the researchers, there is still an ongoing debate over the issue. By trying to identify and account for these potentially flawed studies, they hope to push for a more honest appraisal of alcohol’s risks, which can also include cancer and liver disease.

    “Our findings suggest that the perceived health benefits of low-volume drinking are likely a result of biased study designs. Therefore, it indicates that there may not be a truly safe level of alcohol consumption,” Clay said. “This challenges the notion that moderate drinking is beneficial and highlights the need for updated guidelines that accurately reflect the health risks associated with any level of alcohol consumption.”

    Earlier this February, new research from the Centers for Disease Control and Prevention found that annual alcohol-related deaths in the U.S. have climbed as of late, with an average 178,307 deaths during 2020 to 2021. And while the greatest health risks of alcohol come from binge or chronically heavy drinking, it’s likely that most drinkers could benefit from cutting down on the booze at least a tad.

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    Ed Cara

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  • Can Creatine Protect The Brain From An Unforeseen Injury?

    Can Creatine Protect The Brain From An Unforeseen Injury?

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    Registered Dietitian Nutritionist

    Molly Knudsen, M.S., RDN is a Registered Dietician Nutritionist with a bachelor’s degree in nutrition from Texas Christian University and a master’s in nutrition interventions, communication, and behavior change from Tufts University. She lives in Newport Beach, California, and enjoys connecting people to the food they eat and how it influences health and wellbeing.

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  • HigherDose PEMF Mat Sale 20% Off + Our Review

    HigherDose PEMF Mat Sale 20% Off + Our Review

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    Used regularly by wellness fanatics such as Gabby Bernstein, Lauren Bosstik, and (of course) yours truly, the HigherDose Infrared PEMF Mat is simultaneously calming yet energizing, and it significantly improves my sleep, mood, recovery, and overall well-being.

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