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  • Most Twitter users don’t follow political elites, researchers suggest

    Most Twitter users don’t follow political elites, researchers suggest

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    Newswise — While social media platforms are the primary source of political information for a growing number of people, a majority of Twitter users do not follow either members of Congress, their president or news media, a new study suggests.

    They are much more likely to follow Tom Hanks or Katie Perry than an elected official.

    “Those users who do follow political accounts on Twitter, however, stick to insular online communities and mostly follow and share information from their political in-group,” said Magdalena Wojcieszak, lead author and professor of communication at the University of California, Davis, and the University of Amsterdam.   

    In other words, speaking to ongoing debates about so-called “echo chambers” on social media platforms, the small group of users who do follow political elites display clear political biases and engage with these elites in a very one-sided way.

    The findings come after researchers from UC Davis and New York University analyzed four years’ worth of data from a sampling of 1.5 million Twitter users.

    Researchers concluded that even though the group of social media users who display political biases in their online behaviors is small, it is nevertheless consequential. These users are much more vocal, participatory and active online, thus amplifying the general perception of unprecedented polarization.

    The study was published Friday (Sept. 30) in Science Advances.

    “In this project, we focus on national political elites due to their visibility and national-level influence on public opinion and the political process,” Wojcieszak said. Yet, despite the prominence and impact of presidents, congressmen, journalists, pundits and the news media, researchers found that only 40% of Twitter users follow one or more political “elites.” The remaining 60% follow no political actors at all.

    “Given that we analyzed over 2,500 American political elite accounts including Donald Trump, Joe Biden, prominent pundits including Rachel Maddow and Sean Hannity, and the most popular media outlets such as MSNBC and Fox News, the fact that only 23% of the representative sample of over 1.5 million users follow three of more of such elite accounts is revealing,” Wojcieszak said.

    The authors found that those users who do follow politicians, pundits and news media follow their political in-group at much higher rates than out-group elites (around 90% vs. 10%) and share tweets from in-group elites overwhelmingly more frequently than out-group tweets (at about a 13:1 ratio). And when users share out-group tweets, they tend to add negative comments to these reshares, further reinforcing ideological biases online.

    The research also reveals important ideological asymmetries: conservative users are roughly twice as likely as liberals to share in-group versus out-group content, as well as to add negative commentary to out-group shares.

    Surprising findings

    “Overall, the majority of American Twitter users are not sufficiently interested in politics to follow even a single political or media elite from our list,” Wojcieszak said. Researchers wrote that they found this surprising, since it is generally believed that Twitter users are more politically engaged than the general population.

    Given a growing radicalization in America, decreasing support for democratic norms, and rising support for political violence, concerns about political biases on social media platforms are valid, no matter how small the groups displaying those biases may be.

    “At the same time,” Wojcieszak said, “we have to remember that these political biases are far removed from the everyday online behaviors of most politically disinterested Americans, who simply don’t care and prefer to immerse themselves in entertainment or sports. Our findings should help us all keep in perspective the concerns about the so-called ‘echo chambers’ online.”

     Co-authors of the study include: Andreu Casas, Free University of Amsterdam; Xudong Yu, former doctoral student at UC Davis, now University of Amsterdam; and Jonathan Nagler and Joshua A. Tucker, New York University Center for Social Media and Politics.

    The Center for Social Media and Politics at New York University is supported by funding from the John S. and James L. Knight Foundation, the Charles Koch Foundation, Craig Newmark Philanthropies, the William and Flora Hewlett Foundation, the Siegel Family Endowment, the Bill and Melinda Gates Foundation and the National Science Foundation.

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    University of California, Davis

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  • Long-term study supports link between inflammation and cognitive problems in older breast cancer survivors

    Long-term study supports link between inflammation and cognitive problems in older breast cancer survivors

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    Newswise — LOS ANGELES – Scientists are still trying to understand why many breast cancer survivors experience troubling cognitive problems for years after treatment. Inflammation is one possible culprit. A new long-term study of older breast cancer survivors published today in the Journal of Clinical Oncology and co-led by UCLA researchers adds important evidence to that potential link.

    Higher levels of an inflammatory marker known as C-reactive protein (CRP) were related to older breast cancer survivors reporting cognitive problems in the new study.

    “Blood tests for CRP are used routinely in the clinic to determine risk of heart disease. Our study suggests this common test for inflammation might also be an indicator of risk for cognitive problems reported by breast cancer survivors,” said study lead author Judith Carroll, an associate professor of psychiatry and biobehavioral sciences and faculty member of the Cousins Center for Psychoneuroimmunology at UCLA. 

    The study, called the Thinking and Living with Cancer (TLC) Study, is one of the first long-term efforts to examine the potential link between chronic inflammation and cognition in breast cancer survivors 60 and older, who make up a majority of the nearly 4 million breast cancer survivors in the United States. Previous research has focused largely on younger women and women immediately after therapy, making it difficult to draw conclusions about CRP’s role in long-term cognitive problems among older breast cancer survivors. 

    In TLC, teams of researchers from around the country talked to, and obtained blood samples from, hundreds of breast cancer survivors and women without cancer up to 6 times over the course of 5 years. The study was motivated by hearing from survivors and advocates that cognitive problems are one of their major worries.

    “Cognitive issues affect women’s daily lives years after completing treatment, and their reports of their own ability to complete tasks and remember things was the strongest indicator of problems in this study,” said co-senior study author Dr. Jeanne Mandelblatt, a professor of oncology at Georgetown University who is the lead of the TLC study.

    “Being able to test for levels of inflammation at the same time that cognition was being rigorously evaluated gave the TLC team a potential window into the biology underlying cognitive concerns,” said Elizabeth C. Breen, a professor emerita of psychiatry and biobehavioral sciences at the Cousins Center for Psychoneuroimmunology at UCLA, who also served as co-senior study author.

    Cognition, from the perspective of each woman, was evaluated through a commonly used questionnaire assessing how the women perceive their ability to remember things like names and direction, ability to concentrate, and other aspects of everyday life. The study found higher CRP levels among survivors were predictive of lower reported cognitive function among breast cancer survivors. There was no similar relationship between CRP levels and reported cognition in the women without cancer. 

    Cognitive performance, as measured by standardized neuropsychological tests, failed to show a link between CRP and cognition. The authors say this may indicate women are more sensitive to differences in their everyday cognitive function, self-reporting changes that other tests miss.

    The authors said their study supports the need for research on whether interventions that can lower inflammation – including increased physical activity, better sleep, and anti-inflammatory medications – may prevent or reduce cognitive concerns in older breast cancer survivors. 

    Other study authors include Zev M. Nakamura, Brent J. Small, Xingtao Zhou, Harvey J. Cohen, Tim A. Ahles, Jaeil Ahn, Traci N. Bethea, Martine Extermann, Deena Graham, Claudine Isaacs, Heather S.L. Jim, Paul B. Jacobsen, Brenna C. McDonald, Sunita K. Patel, Kelly Rentscher, James Root, Andrew J. Saykin, Danielle B. Tometich, Kathleen Van Dyk, and Wanting Zhai. The authors declared no conflicts of interest.   

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    University of California, Los Angeles (UCLA), Health Sciences

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  • Exploring Europa Possible with Silicon-Germanium Transistor Technology

    Exploring Europa Possible with Silicon-Germanium Transistor Technology

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    Newswise — Europa is more than just one of Jupiter’s many moons – it’s also one of most promising places in the solar system to look for extraterrestrial life. Under 10 kilometers of ice is a liquid water ocean that could sustain life. But with surface temperatures at -180 Celsius and with extreme levels of radiation, it’s also one of the most inhospitable places in the solar system. Exploring Europa could be possible in the coming years thanks to new applications for silicon-germanium transistor technology research at Georgia Tech.

    Regents’ Professor John D. Cressler in the School of Electrical and Computer Engineering (ECE) and his students have been working with silicon-germanium heterojunction bipolar transistors (SiGe HBTs) for decades and have found them to have unique advantages in extreme environments like Europa.

    “Due to the way that they’re made, these devices actually survive those extreme conditions without any changes made to the underlying technology itself,” said Cressler, who is the project investigator. “You can build it for what you want it to do on Earth, and you then can use it in space.”

    The researchers are in year one of a three-year grant in the NASA Concepts for Ocean Worlds Life Detection Technology (COLDTech) program to design the electronics infrastructure for upcoming Europa surface missions. NASA plans to launch the Europa Clipper in 2024, an orbiting spacecraft that will map the oceans of Europa, and then eventually send a landing vehicle, Europa Lander, to drill through the ice and explore its ocean. But it all starts with electronics that can function in Europa’s extreme environment.

    Cressler and his students, together with researchers from NASA Jet Propulsion Lab (JPL) and the University of Tennessee (UT), demonstrated the capabilities of SiGe HBTs for this hostile environment in a paper presented at the IEEE Nuclear and Space Radiation Effects Conference in July.

    Europa’s Challenge

    Like Earth, Jupiter also has a liquid metal core that generates a magnetic field, producing radiation belts of high-energy protons and electrons from the impinging solar wind. Unfortunately, as a moon of Jupiter, Europa sits squarely in those radiation belts. In effect, any technology designed for Europa’s surface would not only need to be able to survive the cold temperatures but also the worst radiation encountered in the solar system.

    Fortunately, SiGe HBTs are ideal for this hostile environment. The SiGe HBT introduces a nanoscale Si-Ge alloy inside a typical bipolar transistor to nano-engineer its properties, effectively producing a much faster transistor while maintaining the economy-of-scale and low cost of traditional silicon transistors.  SiGe HBTs have the unique ability to maintain performance under extreme radiation exposure, and their properties naturally improve at colder temperatures. Such a unique combination makes them ideal candidates for Europa exploration.

    “It’s not just doing the basic science and proving that SiGe works,” Cressler said. “It’s actually developing electronics for NASA to use on Europa. We know SiGe can survive high levels of radiation. And we know it’s remains functional at cold temperatures. What we did not know is if it could do both at the same time, which is needed for Europa surface missions.”

    Testing the Transistors

    To answer this question, the GT researchers used JPL’s Dynamitron, a machine that shoots high-flux electrons at very low temperatures to test SiGe in Europa-type environments. They exposed ­­SiGe HBTs to one million Volt electrons to a radiation dose of five million rads of radiation (200-400 rads is lethal to humans), at 300, 200, and 115 Kelvins (-160 Celsius).

    “What had never been done was to use electronics like we did in that experiment,” Cressler said. “So, we worked literally for the first year to get the results that are in that paper, which is in essence definitive proof that what we claimed is, in fact, true—that SiGe does survive Europa surface conditions.” 

    In the next two years, the GT and UT researchers will develop actual circuits from SiGe that could be used on Europa, such as radios and microcontrollers. Yet more importantly, these devices could then be seamlessly used in almost any space environment, including on the moon and Mars.

    “If Europa is the worst-case environment in the solar system, and you can build these to work on Europa, then they will work anywhere,” Cressler said. “This research ties together past research that we have done in my team here at Georgia Tech for a long time and shows really interesting and novel applications of these technologies. We pride ourselves on using our research to break new innovative ground and thereby enable novel applications.”

    Citation:  J.W. Teng, G.N. Tzintzarov, D. Nergui, J.P. Heimerl, Y. Mensah, J.P. Moody, D.O. Thorbourn, L. Del Castillo, L. Scheick, M.M. Mojarradi, B.J. Blalock, and J.D. Cressler, “Cryogenic Total-Ionizing-Dose Response of 4th-Generation SiGe HBTs using 1-MeV Electrons for Europa-Surface Applications,” IEEE Nuclear and Space Radiation Effects Conference, July 2022.

     

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    The Georgia Institute of Technology, or Georgia Tech, is one of the top public research universities in the U.S., developing leaders who advance technology and improve the human condition.

    The Institute offers business, computing, design, engineering, liberal arts, and sciences degrees. Its more than 46,000 students, representing 50 states and more than 150 countries, study at the main campus in Atlanta, at campuses in France and China, and through distance and online learning.

    As a leading technological university, Georgia Tech is an engine of economic development for Georgia, the Southeast, and the nation, conducting more than $1 billion in research annually for government, industry, and society. 

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    Georgia Institute of Technology

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  • Better Asthma and COPD Drugs with Fewer Side Effects Are Within Reach

    Better Asthma and COPD Drugs with Fewer Side Effects Are Within Reach

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    Rockville, Md. (September 29, 2022)—Bronchodilators, the most common type of asthma-fighting drug, inhibits contractions of airway smooth muscle that are induced by stimulating receptors on the muscle’s surface. New research highlights a novel mechanism for the drugs and will aid in the development of better medications for the treatment of asthma and chronic obstructive pulmonary disease (COPD). The findings are detailed in a new article by researchers from Dundalk Institute of Technology in Ireland and Queen’s University in Northern Ireland. 

    Asthma and COPD are common lung disorders—caused by excessive constriction of the airways—that make breathing difficult. Bronchodilators,  also known as beta-adrenoceptor agonists, relax airway smooth muscle and open the airways to make breathing easier. These drugs bind to beta-adrenoceptors located on airway muscle cells and cause them to relax.

    Constriction of the airways is regulated in the nerves, which release a chemical called acetylcholine. This chemical causes the airways to constrict and narrow. For patients with COPD, the constrictor effects of acetylcholine are enhanced. It has been long known that beta-adrenoceptor agonists could reverse the constricting effects of acetylcholine on airway smooth muscle, but it has not been fully clear how this occurs. It is important to understand how these medications work to assist with future development of more effective drugs with fewer side effects.

    Read the full article, “M2 muscarinic receptor-dependent contractions of airway smooth muscle are inhibited by activation of β-adrenoceptors,” published ahead of print in Function. Contact APS Media Relations or call 301.634.7314 to schedule an interview with a member of the research team.

     

     

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    American Physiological Society (APS)

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  • Ancient ‘shark’ from China is humans’ oldest jawed ancestor

    Ancient ‘shark’ from China is humans’ oldest jawed ancestor

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    Newswise — Living sharks are often portrayed as the apex predators of the marine realm. Paleontologists have been able to identify fossils of their extinct ancestors that date back hundreds of millions of years to a time known as the Palaeozoic period. These early “sharks,” known as acanthodians, bristled with spines. In contrast to modern sharks, they developed bony “armor” around their paired fins.

    A recent discovery of a new species of acanthodian from China surprised scientists with its antiquity. The find predates by about 15 million years the earliest acanthodian body fossils and is the oldest undisputed jawed fish.

    These findings were published in Nature on Sept. 28.

    Reconstructed from thousands of tiny skeletal fragments, Fanjingshania, named after the famous UNESCO World Heritage Site Fanjingshan, is a bizarre fish with an external bony “armor” and multiple pairs of fin spines that set it apart from living jawed fish, cartilaginous sharks and rays, and bony ray- and lobe-finned fish.

    Examination of Fanjingshania by a team of researchers from the Chinese Academy of Sciences, Qujing Normal University, and the University of Birmingham revealed that the species is anatomically close to groups of extinct spiny “sharks” collectively known as acanthodians. Unlike modern sharks, acanthodians have skin ossifications of the shoulder region that occur primitively in jawed fish.

    The fossil remains of Fanjingshania were recovered from bone bed samples of the Rongxi Formation at a site in Shiqian County of Guizhou Province, South China.

    These findings present tangible evidence of a diversification of major vertebrate groups tens of millions of years before the beginning of the so called “Age of Fishes” some 420 million years ago.

    The researchers identified features that set apart Fanjingshania from any known vertebrate. It has dermal shoulder girdle plates that fuse as a unit to a number of spines—pectoral, prepectoral and prepelvic. Additionally, it was discovered that the ventral and lateral portions of the shoulder plates extend to the posterior edge of the pectoral fin spines. The species has distinct trunk scales with crowns composed of a row of tooth-like elements (odontodes) adorned by discontinuous nodose ridges. Peculiarly, dentine development is recorded in the scales but is missing in other components of the dermal skeleton such as the fin spines.

    “This is the oldest jawed fish with known anatomy,” said Prof. ZHU Min from the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences. “The new data allowed us to place Fanjingshania in the phylogenetic tree of early vertebrates and gain much needed information about the evolutionary steps leading to the origin of important vertebrate adaptations such as jaws, sensory systems, and paired appendages.”

    From the outset, it was clear to the scientists that Fanjingshania‘s shoulder girdle, with its array of fin spines, is key to pinpointing the new species’ position in the evolutionary tree of early vertebrates. They found that a group of acanthodians, known as climatiids, possess the full complement of shoulder spines recognized in Fanjingshania. What is more, in contrast to normal dermal plate development, the pectoral ossifications of Fanjingshania and the climatiids are fused to modified trunk scales. This is seen as a specialization from the primitive condition of jawed vertebrates where the bony plates grow from a single ossification center.

    Unexpectedly, the fossil bones of Fanjingshania show evidence of extensive resorption and remodelling that are typically associated with skeletal development in bony fish, including humans.

    “This level of hard tissue modification is unprecedented in chondrichthyans, a group that includes modern cartilaginous fish and their extinct ancestors,” said lead author Dr. Plamen Andreev, a researcher at Qujing Normal University. “It speaks about greater than currently understood developmental plasticity of the mineralized skeleton at the onset of jawed fish diversification.”

    The resorption features of Fanjingshania are most apparent in isolated trunk scales that show evidence of tooth-like shedding of crown elements and removal of dermal bone from the scale base. Thin-sectioned specimens and tomography slices show that this resorptive stage was followed by deposition of replacement crown elements. Surprisingly, the closest examples of this skeletal remodelling are found in the dentition and skin teeth (denticles) of extinct and living bony fish. In Fanjingshania, however, the resorption did not target individual teeth or denticles, as occurred in bony fish, but instead removed an area that included multiple scale denticles. This peculiar replacement mechanism more closely resembles skeletal repair than the typical tooth/denticle substitution of jawed vertebrates.

    A phylogenetic hypothesis for Fanjingshania that uses a numeric matrix derived from observable characters confirmed the researchers’ initial hypothesis that the species represents an early evolutionary branch of primitive chondrichthyans. These results have profound implications for our understanding of when jawed fish originated since they align with morphological clock estimates for the age of the common ancestor of cartilaginous and bony fish, dating it to around 455 million years ago, during a period known as the Ordovician.

    These results tell us that the absence of undisputed remains of jawed fish of Ordovician age might be explained by under sampling of sediment sequences of comparable antiquity. They also point towards a strong preservation bias against teeth, jaws, and articulated vertebrate fossils in strata coeval with Fanjingshania.

    “The new discovery puts into question existing models of vertebrate evolution by significantly condensing the timeframe for the emergence of jawed fish from their closest jawless ancestors. This will have profound impact on how we assess evolutionary rates in early vertebrates and the relationship between morphological and molecular change in these groups,” said Dr. Ivan J. Sansom from the University of Birmingham.

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    Chinese Academy of Sciences

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  • Low long-term risk of breast cancer recurrence after nipple-sparing mastectomy

    Low long-term risk of breast cancer recurrence after nipple-sparing mastectomy

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    Newswise — September 29, 2022Nipple-sparing mastectomy (NSM) – an increasingly popular option for women undergoing treatment for breast cancer – not only achieves good cosmetic outcomes, but also low long-term risk of recurrent breast cancer, reports a study in the October issue of Plastic and Reconstructive Surgery®, the official medical journal of the American Society of Plastic Surgeons (ASPS). The journal is published in the Lippincott portfolio by Wolters Kluwer.

    Ten years after NSM, the rate of recurrent breast cancer is only 3%, according to the new research, led by ASPS Member Surgeon Mihye Choi, MD, of the Hansjörg Wyss Department of Plastic Surgery, New York University Langone Health. The researchers write, “Nipple-sparing mastectomy remains a viable option in the appropriately indicated patient with regards to long-term cancer recurrence.”

    Not just improved cosmetic outcomes – NSM provides good long-term cancer control

    In the NSM technique, the surgeon preserves the nipple and surrounding tissues for use in immediate breast reconstruction. Compared to conventional mastectomy, NSM allows for a more natural-looking reconstruction, leading to higher patient satisfaction. However, there is little information about the long-term risk of recurrent breast cancer after NSM.

    Dr. Choi and colleagues evaluated breast cancer outcomes in 120 patients undergoing NSM for breast cancer treatment. The analysis included a total of 126 therapeutic NSM procedures. The analysis excluded prophylactic (preventive) NSM procedures to reduce the risk of breast cancer in women at high genetic risk.

    At a median follow-up of 10 years after NSM, the analysis showed low recurrent cancer risks: 3.33% per patient and 3.17% per reconstructed breast. Of the four patients with recurrent cancer, two had local recurrences (breast only) and two had cancer spread to other locations (locoregional recurrence).

    Recurrence risk was higher for women who had cancer involving the lymph nodes. However, on analysis adjusting for other factors, there were no demographic, surgical, or tumor-related variables that predicted the risk of recurrent breast cancer.

    The researchers point out some key limitations of their findings – including selection bias related to the characteristics of patients likely to be considered good candidates for NSM. Most of the patients in the study had early-stage breast cancers: stage 1 in about 45% and stage 0 in 34%.

    The finding of good long-term cancer control is especially important in light of the growing use of NSM and immediate reconstruction for women with breast cancer. “Patients with NSMs have had low locoregional recurrence rates in a retrospective review of patients with a median follow-up of 10-years,” Dr. Choi and colleagues conclude. They add: “Despite low rates of recurrence, close surveillance remains important to continually assess for long-term safety of NSM.”

    Click here to read “Long-Term Cancer Recurrence Rates following Nipple-Sparing Mastectomy: A 10-Year Follow-Up Study“

    DOI: 10.1097/PRS.0000000000009495

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    About Plastic and Reconstructive Surgery

    For over 75 years, Plastic and Reconstructive Surgery® (http://www.prsjournal.com/) has been the one consistently excellent reference for every specialist who uses plastic surgery techniques or works in conjunction with a plastic surgeon. The official journal of the American Society of Plastic Surgeons, Plastic and Reconstructive Surgery® brings subscribers up-to-the-minute reports on the latest techniques and follow-up for all areas of plastic and reconstructive surgery, including breast reconstruction, experimental studies, maxillofacial reconstruction, hand and microsurgery, burn repair and cosmetic surgery, as well as news on medico-legal issues.

    About ASPS

    The American Society of Plastic Surgeons is the largest organization of board-certified plastic surgeons in the world. Representing more than 7,000 physician members, the society is recognized as a leading authority and information source on cosmetic and reconstructive plastic surgery. ASPS comprises more than 94 percent of all board-certified plastic surgeons in the United States. Founded in 1931, the society represents physicians certified by The American Board of Plastic Surgery or The Royal College of Physicians and Surgeons of Canada.

    About Wolters Kluwer

    Wolters Kluwer (WKL) is a global leader in professional information, software solutions, and services for the clinicians, nurses, accountants, lawyers, and tax, finance, audit, risk, compliance, and regulatory sectors. We help our customers make critical decisions every day by providing expert solutions that combine deep domain knowledge with advanced technology and services.

    Wolters Kluwer reported 2021 annual revenues of €4.8 billion. The group serves customers in over 180 countries, maintains operations in over 40 countries, and employs approximately 19,800 people worldwide. The company is headquartered in Alphen aan den Rijn, the Netherlands.

    Wolters Kluwer provides trusted clinical technology and evidence-based solutions that engage clinicians, patients, researchers and students in effective decision-making and outcomes across healthcare. We support clinical effectiveness, learning and research, clinical surveillance and compliance, as well as data solutions. For more information about our solutions, visit https://www.wolterskluwer.com/en/health and follow us on LinkedIn and Twitter @WKHealth.

    For more information, visit www.wolterskluwer.com, follow us on Twitter, Facebook, LinkedIn, and YouTube.

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    Wolters Kluwer Health: Lippincott

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  • Unreliable neurons improve brain functionalities

    Unreliable neurons improve brain functionalities

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    Newswise — The brain is composed of millions of billions of neurons which communicate with each other. Each neuron collects its many inputs and transmits a spike to its connecting neurons. The dynamics of such large and highly interconnected neural networks is the basis of all high order brain functionalities.

    In an article published today in the journal Scientific Reports, a group of scientists has experimentally demonstrated that there are frequent periods of silence in which a neuron fails to respond to its inputs. As opposed to elecronic devices, which are fast and reliable, the brain is composed of unreliable neurons. “A logic-gate always gives the same output to the same input, otherwise electronic devices like cellphones and computers, which are composed of many billions of interconnected logic-gates, wouldn’t function well,” said Prof. Ido Kanter, of Bar-Ilan University’s Department of Physics and Gonda (Goldschmied) Multidisciplinary Brain Research Center, who led the study. “Comparing the unreliability of the brain to a computer or cellphone: one time your computer answers 1+1=2 and other times 1+1=5, or dialing 7 in your cellphone many times can result in 4 or 9. Silencing periods would appear to be a major disadvantage of the brain, but our latest findings have shown otherwise.”

    Contrary to what one might think, Kanter and team have demonstrated that neuronal silencing periods are not a disadvantage representing biological limitations, but rather an advantage for temporal sequence identification. “Assume you would like to remember a phone number, 0765…,” said Yuval Meir, a co-author of the study. “Neurons which were active when the digit 0 was presented might be silenced when the next digit 7 is presented, for example. Consequently, each digit is trained on a different dynamically created sub-network, and this silencing mechanism enables our brain to identify sequences efficiently.”

    The brain silencing mechanism is a proposed source for a new AI mechanism, and in addition has been demonstrated as the origin for a new type of cryptosystem for handwriting recognition at automated teller machines (ATMs). This cryptosystem allows the user to write his personal identification number (PIN) on an electronic board rather than clicking a PIN into the ATM. The sequence identification developed by Kanter and team, based on neuronal silencing periods, is not only capable of identifying the correct PIN but also the user’s personal handwriting style and the timing in which each digit of the PIN is written on the board. These added features act as safeguards against stolen cards, even if a thief knows the user’s PIN.

    This latest research by Kanter and team shows that it is not always beneficial to improve the unreliablilty of stuttered neurons in the brain, because they have advantages for higher brain functions.

    See video here.

     

     

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    Bar-Ilan University

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  • Economic Loss from U.S. Cigarette Smoking Topped Almost $900 Billion in 2020, New Study Shows

    Economic Loss from U.S. Cigarette Smoking Topped Almost $900 Billion in 2020, New Study Shows

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    EMBARGOED FOR RELEASE – 6:30 p.m., EDT – September 28, 2022

    Newswise — ATLANTA, September 28, 2022 — New findings by the American Cancer Society (ACS) found cumulative economic losses from cigarette smoking topped $891 billion in 2020, or 4.3% of the United States Gross Domestic Product. The economic loss significantly outpaced the cigarette industry’s $92 billion revenue by nearly a ten-to-one ratio. The study was published today in the journal The Lancet Public Health.

    This economic modelling study is one of the first to provide a comprehensive measure of economic loss from cigarette smoking on a state-by-state level. On average, states lost $1,100.00 per capita income annually from cigarette smoking. Kentucky ($1,674.00), West Virginia ($1,605.00) and Arkansas ($1,603.00) suffered the largest per capita income losses, while Utah ($331.00), Idaho ($680.00) and Arizona ($701.00) had the smallest per capita income losses.

    “Economic losses from cigarette smoking far outweigh any economic benefit from the tobacco industry — wages, and salaries of those employed by the industry, tax revenue, and industry profit combined,” said Dr. Nigar Nargis, senior scientific director, tobacco control research at the American Cancer Society. “As a society, we can mitigate these economic losses through coordinated and comprehensive evidence-based tobacco control measures, which encourage people to quit smoking and prevent people from starting to smoke in the first place.”

    The U.S. Department of Health and Human Services set the Healthy People 2030 goal to reduce smoking from 14% of the adult population in 2018 to 5% by 2030. According to study authors, reaching this goal through tobacco control efforts at the national, state, and local levels would considerably reduce the economic loss attributable to smoking.

    “The Healthy People 2030 goal provides an important target that will help reduce smoking and correspondingly the negative economic impact of tobacco use,” said Nargis. “In addition, hitting this target will help divert scarce resources away from treating tobacco-related illnesses towards growing market productivity and household income.”

    “The damage this industry causes on individuals’ lives and our nation’s economy is horrifying,” said Lisa Lacasse, president of the American Cancer Society Cancer Action Network (ACS CAN). “It’s particularly alarming, but not surprising, to see some of the states with the highest economic loss have the weakest tobacco control policies in place. We know what works to reduce tobacco use and lessen this burden and it’s past time we get it done. Passing policies proven to reduce tobacco use including regular and significant tobacco tax increases, adequate funding for tobacco prevention and cessation programs and comprehensive smoke-free laws has a huge impact on reducing tobacco-related diseases like cancer and addressing the financial burden this product poses on state economies and the nation.”

    Dr. Ahmedin Jemal is senior author of the study. Other ACS authors include:  Dr. Samuel Asare, Zheng Xue, Dr. Anuja Majmundar, Dr. Priti Bandi, Dr. Farhad Islami, and Dr. Robin Yabroff.

    Resources from the ACS on quitting smoking can be found here.

     

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    About the American Cancer Society The American Cancer Society is on a mission to free the world from cancer. We invest in lifesaving research, provide 24/7 information and support, and work to ensure that individuals in every community have access to cancer prevention, detection, and treatment. For more information, visit cancer.org.

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    American Cancer Society (ACS)

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