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Tag: vision and hearing

  • 3D printed cornea restores sight in world first

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    Surgeons at Rambam Eye Institute have made medical history.

    They restored sight to a legally blind patient using a fully 3D printed corneal implant grown entirely from cultured human corneal cells. This marked the first time a corneal implant that did not rely on donor tissue had ever been transplanted into a human eye.

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    A breakthrough that turns one donor cornea into hundreds

    The cornea came from a healthy deceased donor and was then multiplied in the lab. Researchers used the cultured cells to print about 300 transparent implants with Precise Bio’s regenerative platform. 

    Their system builds a layered structure that looks and behaves like a natural cornea. It is designed to provide clarity, strength and long-term function.

    HOW A TINY RETINAL IMPLANT IS HELPING PEOPLE REGAIN THEIR SIGHT

    Since donor shortages prevent millions from receiving sight-saving care each year, this approach could transform access. Many patients in developed countries wait only a few days for a transplant, while others wait years due to low tissue availability. A single donor cornea that can create hundreds of implants changes that equation. 

    The surgery used a fully 3D printed corneal implant grown from cultured human cells and restored sight to a legally blind patient. (Rambam Eye Institute)

    The surgery that proved it works

    Professor Michael Mimouni, director of the Cornea Unit in the Department of Ophthalmology at Rambam Eye Institute, led the surgical team. He described the moment as unforgettable because the lab-grown implant restored sight to a real patient for the first time.

    He says, “What this platform shows and proves is that in the lab, you can expand human cells. Then print them on any layer you need, and that tissue will be sustainable and work. We can hopefully reduce waiting times for all kinds of patients waiting for all kinds of transplants.”

    The procedure is part of an ongoing Phase 1 clinical trial that assesses safety and tolerability in people with corneal endothelial disease. This achievement reflects years of work across research labs, operating rooms and industry. It also shows how coordinated teams can push new treatments from concept to clinical reality.

    How the science fits into a bigger future

    The breakthrough will have a permanent home in Rambam’s upcoming Helmsley Health Discovery Tower. The new Eye Institute will consolidate care, training and research under one roof. It aims to speed the move from emerging science to real-world treatment for patients across Northern Israel and beyond.

    Precise Bio says its 3D printing system could eventually support other tissues like cardiac muscle, liver and kidney cells. That future will require long trials and extensive validation, but the path now looks more achievable.

    POPULAR WEIGHT-LOSS DRUGS LINKED TO SUDDEN VISION LOSS, RESEARCH SUGGESTS

    Surgeon in blue scrubs speaks inside a brightly lit operating room with medical equipment behind him.

    Professor Michael Mimouni led the surgical team at Rambam Eye Institute’s Cornea Unit. (Rambam Eye Institute)

    What this means for you

    If corneal disease affects someone in your family, this work brings new hope. Donor tissue may continue to play a role in many regions, but lab-grown implants offer a way to expand access where shortages hold patients back. The success of this first transplant also suggests a future where regenerative medicine supports many types of tissue repair.

    This milestone also shows how long scientific breakthroughs take to reach real patients. The first 3D printed cornea design appeared in 2018 and only now reached human use. Even so, the progress feels fast when the result is restored sight.

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    EYE DROPS MAY REPLACE READING GLASSES FOR THOSE STRUGGLING WITH AGE-RELATED VISION LOSS

    Kurt’s key takeaways

    This successful transplant marks a turning point for eye care. It suggests a world where the limits of donor supply do not decide who receives sight-saving surgery. As more trial results arrive, we will see how far this technology can scale and which patients stand to benefit first.

    If regenerative implants become common, what medical challenge should researchers focus on next? Let us know by writing to us at Cyberguy.com

    Woman peers over her reading glasses to look into book she holds in her hands

    The breakthrough shows how one donor cornea can generate hundreds of lab-grown implants, offering new hope for people who face long waits for sight-saving treatment. (iStock)

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  • How a tiny retinal implant is helping people regain their sight

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    A new study in The New England Journal of Medicine revealed that the PRIMA brain computer interface (BCI) retinal implant helped people with advanced age-related macular degeneration regain some central vision. The device uses a tiny 2 millimeter by 2 millimeter photovoltaic implant that is only 30 micrometers thick, and thinner than a strand of hair. It sits beneath the retina and works with a special pair of smart glasses. The glasses capture images and send them as near-infrared light to the implant. The implant converts that light into small electrical signals that stimulate the optic nerve. This process mimics how healthy retinal cells normally send visual information to the brain.

    The study followed 38 participants, 32 of whom completed one year of follow-up. Twenty-six patients experienced measurable improvement in vision, which equals about 80% of the group. Many participants could read letters, numbers and even full pages of text again. Although the restored vision is black and white and slightly blurry, the results are remarkable for people who once believed they would never see clearly again.

    WORLD’S THINNEST AI GLASSES FEATURE BUILT-IN AI ASSISTANT

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    Why this matters for AMD treatment

    Age-related macular degeneration, often called AMD, is one of the leading causes of irreversible blindness in older adults. Until now, available treatments could only slow down vision loss. None of them could restore what had already been lost.

    The PRIMA implant works with smart glasses to bring central vision back to life. (PRIMA by Science)

    The PRIMA implant takes a different approach. It directly replaces the missing function of the retina by turning light into electrical signals. Patients can still use their natural peripheral vision while the implant restores some central vision. This combination creates a more complete visual experience.

    The trial showed that the surgery is generally safe. Most side effects occurred within the first two months and resolved soon after. Importantly, the implant did not reduce the patients’ remaining natural peripheral vision. Researchers call this a major step toward restoring sight rather than only slowing its decline.

    The PRIMA implant was developed by Science Corporation, a brain-computer interface company founded by Max Hodak, who previously cofounded Neuralink. Science Corporation acquired the PRIMA technology from the French firm Pixium Vision, continuing its development toward clinical use.

    EYE DROPS MAY REPLACE READING GLASSES FOR THOSE STRUGGLING WITH AGE-RELATED VISION LOSS

    A visual implant is seen next to a key.

    The tiny chip sits under the retina and turns light into visual signals. (PRIMA by Science)

    What this means for you

    If you or someone you love lives with late-stage AMD, this breakthrough may offer real hope. For the first time, there is a device that can restore some sight instead of only preserving what remains. You may want to talk with your ophthalmologist about upcoming trials or future approval of the PRIMA system in your area. The company behind the technology has already applied for European approval, and a process with the U.S. Food and Drug Administration is underway.

    Regaining even partial central vision can make a big difference. Reading text, recognizing faces or simply moving independently becomes possible again. This progress also shows how fast medical innovation is moving. Patients who were once told that nothing could help may soon have a chance to see again.

    It is also a reminder to stay informed. Treatments that were once experimental are becoming available sooner than expected. Discussing new technologies with your doctor helps you understand timing, eligibility and what kind of results you can realistically expect.

    Woman gets eye exam at doctor's office

    This breakthrough offers new hope for people living with advanced macular degeneration. (PeopleImages/Getty Images)

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    Kurt’s key takeaways

    The PRIMA retinal implant represents a shift in how scientists and doctors think about blindness caused by AMD. For decades, the focus was on slowing down the disease. Now, researchers are proving that restoration is possible. While this generation of the implant provides limited black and white vision, it gives real, functional sight to people who had none. That alone changes lives. More work remains to improve image clarity, color perception and comfort. Still, this is only the beginning. Future versions of the device and smart glasses may make vision restoration even more effective and accessible.

    If you could regain even part of your sight through new technology, would you take the opportunity and experience the world in a whole new way? Let us know by writing to us at CyberGuy.com.

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