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Tag: Stony Brook University

  • Long Island Association adds seven new board members | Long Island Business News

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    THE BLUEPRINT:

    • LIA elects seven new board members from major Long Island institutions.

    • New members represent , research, defense and accounting.

    • Leaders elected to help bolster economic growth and competitiveness.

    • LIA says new voices will support innovation and small-business success.

    The recently elected seven new members to its . The new board members serve in higher education, accounting services, scientific research and defense manufacturing, bringing expertise in their fields.

    These members, all from organizations that were already represented on the board, were elected to support the LIA’s mission to advance regional economic and business development.

    “We are excited to welcome these accomplished and knowledgeable leaders to the LIA Board of Directors,” Lawrence Waldman, chairman of the LIA, said in a news release about the board members.

    “Their leadership and industry expertise will bring fresh perspectives and help guide our mission to strengthen Long Island’s competitiveness and economic resilience,” he added.

    The board members include Dr. Jerry Balentine, president of New York Institute of Technology, with a campus in Old Westbury; Damon Brady, product line director of , with locations in Greenlawn; Andrea Goldsmith, president of ; John Hill, interim director of ; Craig Savell, managing principal of the New York metro region of , which includes offices in Uniondale and Melville; Christopher Storm, interim president of president of , whose main campus is in Garden City; and Jerry Ward, office managing partner of , with a location in Jericho.

    The LIA’s Board of Directors comprises “a cross-section of our region’s leading industries and institutions, and these new voices will contribute to the LIA’s efforts to ensure a thriving economy,” Matt Cohen, president and chief executive of the LIA, said in the news release.

    “The work of the new board members at their respective companies and organizations is critical to both the growth of our innovation economy and success of small businesses, and we look forward to having their input as we advocate for a prosperous Long Island,” he said.


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    Adina Genn

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  • New York invests $300M in Stony Brook quantum hub | Long Island Business News

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    THE BLUEPRINT:

    • pledges $300M for hub at Stony Brook

    • Hub will feature the state’s first hybrid quantum

    • Facility expected to open in 2029 after three years of development

    • Project aims to enhance secure internet and tech-driven economic growth

    New York State is investing $300 million to launch the Quantum Research and at . The initiative aims to integrate research, computing and to address complex societal challenges and build a “faster, smarter and more secure internet,” according to the university.

    The 150,000-square-foot facility will be home to the Stony Brook Quantum Institute, the state’s first university-based hybrid quantum data center, and the SUNY Stony Brook Quantum Education Consortium. Planning and construction are expected to take about three years, with an anticipated opening in 2029.

    Calling Stony Brook University a “research powerhouse,” Gov. said in a news release that the university “will now be able to reach new heights in quantum.”

    Hochul made the announcement on Wednesday at Stony Brook’s New York State Center of Excellence in Wireless and Information Technology.

    “We know that to provide our state and nation with a brighter future, we need to invest today, and that is what New York is committed to do,” she said.

    The funding comes at a time when organizations are navigating pauses and cuts in federal funding.

    Hochul said that “when national investment in research and innovation is at risk, New York State is doubling down, and SUNY is on the move.”

    Speaking about Stony Brook University’s quantum network, which she described as the largest in the nation, President Andrea Goldsmith said in the news release that through “such transformative research, in partnership with New York State and SUNY, we are accelerating technological advancement and its positive impact across our state and beyond.”

    The hub, she said “will spearhead the future of and networking. Today’s historic investment further advances Stony Brook’s leadership in quantum science and technology, and showcases the bold ground-breaking research across our campus that delivers solutions to society’s most pressing challenges.”

    Empire State Development President, CEO and Commissioner Hope Knight said the investment would drive economic growth.

    “The creation of the Quantum Research and Innovation Hub marks the next step in expanding research capacity, cultivating top talent, and advancing breakthroughs that will drive economic growth and cement New York’s position as a global leader in quantum technology,” Knight said.

    “This investment will give Long Island the bandwidth to be at the forefront of the next era of science and innovation,” Stony Brook alumna and State Senator Monica Martinez said in the news release. “The future Quantum Research and Innovation Hub at Stony Brook will build the infrastructure necessary to expand human understanding and drive the discoveries of tomorrow, creating new economic opportunities that strengthen our region and position New York to lead.”

     

     

     

     


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    Adina Genn

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  • Simons Foundation makes $500M gift to Stony Brook University | Long Island Business News

    Simons Foundation makes $500M gift to Stony Brook University | Long Island Business News

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    The Simons Foundation announced a $500 million endowment gift to Stony Brook University.

    The foundation, which aims to advance research in mathematics and the basic sciences, announced the gift from its Manhattan headquarters.

    This combined gift from the Simons Foundation and Simons Foundation International, is expected to grow by up to $1 billion in contributions for the university’s endowment through “New York State’s 1:2 endowment matching program and other philanthropy inspired by this gift,” according to a news release about the donation.

    The gift is intended to “cement” Stony Brook as the state’s “flagship research institution,” and the university’s “commitment to educational excellence, research innovation and community support,” according to the news release.

    Impacts from investments that stem from the gift include student scholarships, endowed professorships innovative research and clinical care, according to the university.

    “The Simons Foundation mission is to advance the frontiers of research in mathematics and the basic sciences,” Foundation President David Spergel said in a statement.

    “For more than a decade, we have been proud to give to an institution that is at the forefront of educational excellence in the sciences,” Spergel added. “It is our sincere hope that this large unrestricted gift will build upon our previous support to Stony Brook, giving students and faculty the ability to dream big and engage in transformative research.”

    “A world-class, public education has the ability to transform the lives of New Yorkers, which is why in this year’s budget we created the first-ever matching fund for endowment contributions for SUNY’s university centers,” Governor Kathy Hochul said in a statement. “Time and again, Stony Brook University forges a bold path forward, from innovation happening at Brookhaven Lab to the economic development throughout Long Island. With this remarkable contribution from the Simons Foundation, Stony Brook will continue to excel as an internationally recognized research institution and give students the tools they need to succeed.”

    “We are eternally grateful to Jim and Marilyn Simons and Simons Foundation President David Spergel for their unparalleled support of Stony Brook University,” University President Maurie McInnis said in a statement.

    “In 1960, we were given a mandate by the State Board of Regents to become a university that would ‘stand with the finest in the country,’” she added. “Thanks in large part to the generosity of the Simons Foundation, we have done just that, and we have no intention of slowing down. We take seriously our commitment to our students, our faculty and our broader community to advance knowledge and contribute to the most significant challenges facing our society. We are so proud of all that we have accomplished as an institution and our best days are ahead of us.”

    “I joined Stony Brook University in 1968 as chair of their Department of Mathematics,” Simons Foundation Co-Founder Jim Simons said in a statement. “I knew then it was a top intellectual center with a serious commitment to research and innovation. But Stony Brook also gave me a chance to lead — and so it has been deeply rewarding to watch the university grow and flourish even more. Marilyn and I are proud to support this outstanding public university that has given us so much.”

    “As a Stony Brook graduate, I know firsthand the role that a quality education plays in the trajectory of one’s life,” Simons Foundation Co-Founder Marilyn Simons, ’74, PhD ’84, said in a statement.

    “I am proud of the education I received there,” she added. “Jim and I want to ensure that Stony Brook continues to serve its students with the highest level of educational excellence and with world-class resources. The foundation’s gift will also help give those from underserved communities the opportunity to reach their full potential. We look forward to seeing this institution continue to thrive.”

    Since Jim and Marilyn Simons made their first gift of $750 in 1983, they and the Simons Foundation have committed more than $1.2 billion to Stony Brook, while also inspiring over 2,100 other donors to give to the university. Their support has led to growth impacting every corner of the Stony Brook campus and beyond, from the Renaissance School of Medicine and the Simons Center for Geometry and Physics to Stony Brook’s Simons STEM Scholars program, nine endowed chairs and professorships in economics, and more.

    last month, following Stony Brook’s successful bid to serve as the anchor institution of the The New York Climate Exchange, the Simons Foundation committed $100 million to the project’s expected $700 million budget. These funds will help establish this climate research, education and green-economy training hub, set to transform how the world responds to the climate crisis and pioneer investigation into environmental, community and health outcomes and impacts.

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    Adina Genn

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  • Stony Brook University to anchor NYC climate center on Governor’s Island | Long Island Business News

    Stony Brook University to anchor NYC climate center on Governor’s Island | Long Island Business News

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    Stony Brook University will anchor the New York Climate Exchange on Governor’s Island in New York City. The announcement was made Monday by New York City Mayor Eric Adams and The Trust for Governors Island.

    Simons Foundation and Bloomberg Philanthropies pledged $150 million in combined support for the Stony Brook University-led center. Billed as a “first of its kind,” the center will develop and deploy “dynamic solutions to our global climate crisis, while also acting as a hub for New Yorkers to benefit from the rapidly evolving green economy,” according to a news release from Stony Brook University.

    “Today, here in the heart of New York Harbor, we are taking a giant leap toward a cleaner, greener, more prosperous future for every New Yorker with the ‘New York Climate Exchange,’” Adams said in a statement.

    “This first-of-its-kind project will make New York City a global leader in developing solutions for climate change while creating thousands of good-paying green jobs for New Yorkers and infusing $1 billion into our city’s economy,” Adams said. “Where some people see challenges, New Yorkers see opportunities, and this team and this project are leading the charge.”

    The center will bring together world leaders and climate experts, as well as serve as a green job-training center for New Yorkers who want to build careers in this field.

    The center will also partner with other institutions, including the Pratt Institute, Pace University, New York University, the City University of New York, SUNY Maritime College, Brookhaven National Labs and IBM. Together they will aim to address the challenges surrounding climate change, “including research that becomes commercially viable and ideas that lead to immediate action on the local and global levels,” according to Stony Brook University.

    “We are honored, excited, and proud to partner with the City of New York to build this historic center that will cement New York City as the world leader on climate change, the most pressing issue of our time,” Stony Brook University President Maurie McInnis said in a statement.

    “Up until now, the development of climate solutions has been siloed, with world leaders separate from expert scientists separate from the on-the-ground green workforce,” she added. “As an international leader on climate and as the leading public research institution in New York, Stony Brook University will bring stakeholders together from the academic, government and business communities to make the Climate Exchange the center of research, innovation, education and collaboration to address this global crisis.”

    The Simons Foundation, together with Simons Foundation International, pledged a total of $100 million as matching gift support for The Exchange – the largest gift to date under Simons Foundation President David Spergel’s leadership and the second-largest in Stony Brook’s history.

    “We are honored to partner with Stony Brook and The Exchange,” Simons Foundation President David Spergel said in a statement.

    “Our partnership with Stony Brook goes back many years and together we’ve made great progress in both basic and health sciences,” he added. “This enduring relationship is a source of great pride for all of us at the Simons Foundation. Stony Brook has catapulted to the forefront of higher education through its remarkable strength as a research institution and its unequaled focus on equity and access. I cannot think of a more qualified institution to lead this historic fight against climate change — a fight that must be met with innovation, intellect and tenacity.”

    Bloomberg Philanthropies donated $50 million to the project, as part of the philanthropy’s commitment to New York City, the fight against climate change, and improving higher education in New York and beyond.

    “This great news is 22-years in the making,” Michael Bloomberg, the former mayor of New York City and founder of Bloomberg Philanthropies and Bloomberg LP.

    “As a candidate for mayor in 2001, I proposed transforming Governors Island into a park and university campus, and the next year Gov. Pataki and I worked with President Bush to return the island to city and state for $1,” he added.

    That’s when, Bloomberg said, his administration “opened a public school on the island and began building an extraordinary public park, but over time it became clear that the city needed greater control of its development. In 2010, we worked with Governor Paterson to cede the island to the city, which allowed us to lay the foundation for fulfilling our original vision of a year-round destination with a university presence that would bring new life and jobs. Now, thanks to Mayor Adams’ leadership, that vision is being fulfilled through a groundbreaking partnership with Stony Brook University that holds so much potential, The New York Climate Exchange. Bloomberg Philanthropies is glad to join Jim and Marilyn Simons and others in supporting it, as part of our global efforts to help cities lead the way in tackling climate change. This is a great day for the island, for New York City’s future, and for the fight against climate change.”

    “It is becoming clear year-after-year in New York, and around the world, that the impacts of climate change are real and are here,” Kevin Reed, associate dean for research and associate professor at Stony Brook’s School of Marine and Atmospheric Sciences, said in a statement.

    “By partnering with communities, industries, governments, and universities, The Exchange will help to accelerate the implementation of urban solutions to these climate impacts through an interactive research ecosystem where community engagement is paramount,” Reed said. “As a climate scientist, I recognize that New Yorkers need solutions to the climate crisis now, and The Exchange will help to make that a reality.”

    Skidmore, Owings & Merrill (SOM) in collaboration with MNLA, Buro Happold, and Langan Engineering conceived the design and operations of The Exchange. The center is intended to serve as a model for sustainability with a net zero center that complements the natural landscape of Governors Island and the urban landscape of New York City.

    “It is a tremendous honor to design a new kind of campus: one that not only sets the stage for our post-carbon world, but also centers a compelling new public realm for all New Yorkers,” Colin Koop, SOM design partner, said in a statement.

    “Our design embodies this stewardship by weaving sinuous mass timber pavilions through the rolling landscape of the park and reusing the historic building fabric of Governors Island,” Koop added. “Together, these spaces will cultivate advances in climate research and pilot new technologies that can be deployed across the city, and eventually the world. We look forward to working with the Governors Island Trust, Stony Brook University, and our team of design and engineering collaborators to bring this important project to life.”

    The Exchange will include a 400,000-square-foot interactive “living laboratory” with green-designed building space, including research labs, classroom space, exhibits, greenhouses, mitigation technologies, and housing facilities.

    Officials say it will include all-electric buildings for the entire campus with on-site solar electrical generation and battery storage meeting 100% of energy demand with net-positive capability to serve the local grid. And 100% of non-potable water demand will be met with rainwater or treated wastewater. In addition, 95% of waste will be diverted from landfills, making this one of the first sites in the U.S. to achieve true-zero waste certification. Also featured is a climate-resilient design including new buildings raised to 18 feet, with no basements and living shorelines. All new and renovated buildings will meet “Living Building Challenge” standards, and will be the first buildings in the city to achieve this certification.

    A research and technology accelerator will serve to source and nurture ideas, projects, and new ventures that aim to the climate crisis.

    The center will also include a citizens advisory council, composed of key local stakeholders to ensure that partners’ and neighbors’ voices are heard and amplified as it looks to jointly develop and implement new climate solutions, including those that affect low-income communities of color.

    Stony Brook University formed international partnerships with academic partners outside of New York City, research foundations and social justice organizations to create The Exchange.

    For these kinds of partnerships – locally and nationally – the potential for collaboration brings promise.

    “Brookhaven Lab researchers have played key roles in designing and conducting landmark climate studies from the Arctic to the Amazon for the U.S. Department of Energy,” Brookhaven National Laboratory Interim Director Jack Anderson said in a statement. “We’re excited at the prospect of collaborating with other researchers through the New York Climate Exchange as part of this new, important initiative focused on developing the next generation of climate experts and creating equitable climate solutions.”

     

     

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    Adina Genn

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  • New Anti-Cancer Compound Originally Discovered at Stony Brook Takes a Major Step Towards Clinical Development

    New Anti-Cancer Compound Originally Discovered at Stony Brook Takes a Major Step Towards Clinical Development

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    Newswise — STONY BROOK, NY, February 28, 2023 –  For the past few decades, Dr. Iwao Ojima has been working in his Stony Brook University Department of Chemistry Laboratory and through the Institute of Chemical Biology & Drug Discovery (ICB&DD) to develop next-generation anti-cancer agents. One of these agents – a second-generation taxane conjugate in a nanoemulsion formulation (called NE-DHA-SBT-1214) – has shown great promise against solid tumors – particularly against colorectal cancer. The taxane compounds were licensed to a Stony Brook University spinout, TargaGenix, Inc., in 2016, to advance their development toward clinical use. Since then, TargaGenix has further developed the compounds, addressing formulation, toxicity and in vivo efficacy, and has now attracted significant investment into NE-DHA-SBT-1214.

    TargaGenix plans to work with its partners to develop the new taxane as a stand-alone drug, as well as look to use it in combination with other treatment modalities, including immune-oncology agents. The company and its collaborators expect to advance the drug development into clinical testing in humans in the near future.

    TVM Capital Life Science (TVM) is committing up to $24 million for a development program in order to help advance NE-DHA-SBT-124 to market as an alternative medicine to treat colorectal cancer and other solid tumors.

    Taxanes are a class of oncology drugs widely used to treat solid tumors. They are represented by paclitaxel, docetaxel and cabazitaxel. The drug class inhibits tumor growth by blocking cancer cell mitosis. However, multidrug resistance (MDR) and cancer stem cells (CSCs), along with various adverse effects, often hamper the effective use of these drugs. Dr. Ojima and his team developed a highly potent second-generation taxane conjugated to DHA (widely known omega-3 fish oil supplement) in nanoemulsion formulation. The agent (NE-DHA-SBT-1214) exhibited not only excellent activity against MDR solid tumor xenograft models, but also against CSC-initiated tumor xenografts models.

    “A primary indication for NE-DHA-SBT-1214 is colorectal cancer, which is a very challenging cancer to deal with due to strong multidrug resistance,” says Dr. Ojima, Distinguished Professor and Director of the ICB&DD. “But it also shows promise with pancreatic cancer and prostate cancer in preclinical testing. For example, we examined NE-DHA-SBT-1214 in combination with PLD-1 antibodies for pancreatic cancer. The combination therapy exhibited superior results over the current best standard treatment against this deadly disease.”

    The new taxane conjugate is formulated using a nanotechnology called nanoemulsion, originally developed by Dr. Mansoor Amiji at Northeastern University. This nano-formulation together with DHA-conjugation allows for tumor-selective drug delivery by means of an “Enhanced Permeability and Retention (EPR)” effect characteristic to nano-size particles, as well as a controlled release of highly potent second-generation taxane. This has been shown in preclinical testing to make the taxane efficacious against MDR and CSCs within the tumor.

    “The novel taxane originally developed by Dr. Ojima and his team shows great promise in pre-clinical studies of colorectal and pancreatic cancer, two of the deadliest cancers in humans. I am delighted that after decades of research, the drug will be entering clinical trials in patients. This example illustrates the importance of research in Stony Brook’s basic science departments for developing new potential treatments for cancer,” says Peter Igarashi, MD, Dean of the Renaissance School of Medicine at Stony Brook University.

    “Taxanes have been a cornerstone of cancer treatment for decades, but they can come with significant side effects, and treated cancers frequently recur,” says James E. Egan, CEO of TargaGenix.  “We are excited to have TVM’s strong support and to now have the resources to further the development of this potentially game-changing molecule,” adds Egan, who received his PhD at Stony Brook University in Molecular Pharmacology. 

    Stony Brook University’s Intellectual Property Partners (IPP) worked with TargaGenix to secure TVM’s investment.

    “My office worked closely with James and TVM through this investment, and we are elated to see it close,” says Sean Boykevisch, PhD, Director of IPP. “The funding will accelerate this new potential therapeutic into the clinic, where we hope it will provide meaningful clinical responses and potentially become a new standard of care.”

    About TVM Capital Life Science

    TVM Capital Life Science (“TVM”) is a leading international venture capital firm focused on investing in life science innovations. The company has a highly experienced transatlantic investment team and approximately $900 million under management. TVM’s portfolio focuses on therapeutics and medical technologies from North America and the EU that represent differentiated first-in-class or best-in-class assets with the potential to transform standard of care.

    TVM pursues a unique two-pronged strategy, financing innovative early-stage therapeutics through a single asset company approach (Project-Focused Company, PFC) that leverages the firm’s strategic relationship with global pharmaceutical firm, Eli Lilly and Company. TVM also invests in differentiated commercial-stage medical technologies and late clinical-stage therapeutics.

    With its early-stage investments, TVM follows several key principles, which include increasing capital efficiency, streamlining development timelines and soliciting buyer input at the time of investment. This strategy has been validated through successful exits such as AurKa Pharma, Inc. and Acanthas Pharma, Inc.

    The TVM investment team has worked together for over a decade to effectively utilize this innovative approach to maximize returns for investors and finance new therapies and technologies to meaningfully improve patient lives.

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