Selma Blair got real about her Multiple Sclerosis diagnosis. In conversation with SHE Media CEO Samantha Skey at Flow Space 2025 Women’s Health Summit, the Cruel Intentions actress opened up about her health and public perception of her disability.
The actress was diagnosed with Multiple Sclerosis, a central nervous system condition that damages nerves, affecting the electrical signals in the brain, in 2018. The star has been open about her symptoms, including numbness and tingling, before her diagnosis, and found comfort in finding a community. “When I [posted about my RMS on Instagram] I saw that there was a whole world that felt seen or could relate to someone having chronic health issues,” Blair recalled.
When it came to being at public events, Blair didn’t shy away from showing off her assistive device. “I showed up on the red carpet with a simple cane—a cute cane that my manicurist embedded a little with diamonds— so it felt very of the moment,” she said. “But I didn’t realize that was such a statement. When young girls and young boys were putting things on Instagram with their canes or assistive devices, I felt empowered for them.”

However, with all the photos and the glam, there were sure to be trolls online whenever she stepped out in public. Some people thought that Blair was faking her disability when she arrived on a red carpet without her cane, and while she was wearing heels. “Don’t worry. We’ll live long enough, we’ll all be disabled,” she responded to the haters. “I’m vain, I want to wear heels. I don’t care. I gotta keep moving! These are the shoes that I want to wear.“
Though she started having symptoms earlier in life, she finally got the courage to stand up for herself and express her pain to her doctors. “I realized that we do have to learn to be our own advocates, that we do not have to be compliant or be polite,” she said. “The medical system can be very daunting, but it’s not infallible. We know our problems with our health; that feeling should be much stronger than the fear we have of expressing it to a doctor.”
Blair also opened up about how her everyday life was affected by her disability. “A lot of my friends changed because it’s really hard if you know someone who has a chronic illness. You can seem fine, but you’re not necessarily fine, and it’s really hard to have love in my life in any way, because people take it personally. My son is my priority, so is my work and myself. Some things do fall by the wayside, and people take it personally. It’s hard going out and meeting every engagement, or give people the attention they deserve, but that is just part of my identity.”
Lea Veloso
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