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Tag: Rutgers University-New Brunswick

  • Rutgers Health Poison Control Expert Available to Discuss CDC Warning About Tianeptine

    Rutgers Health Poison Control Expert Available to Discuss CDC Warning About Tianeptine

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    Newswise — Diane Calello, Executive and Medical Director of the New Jersey Poison Control Center,at Rutgers New Jersey Medical School, is available to discuss the Centers for Disease Control and Prevention’s report warning that readily purchased tianeptine products (marketed as “Neptune’s Fix”) might contain synthetic cannabis.

    In the past six months, 20 cases of tianeptine ingestion associated with severe adverse effects, including seizure and cardiac arrest, were reported in New Jersey—a sharp increase from the poison control center’s baseline of two or fewer exposure calls per year.

    The following quotes from Dr. Calello can be used in stories about tianeptine products:

    Although products containing tianeptine can be purchased anywhere from gas stations and convenience stores to smoke shops and online, they are not safe to use and have been linked to an outbreak of poisoning here in New Jersey and across the country.

    Tianeptine, an antidepressant with opioid effects, is a dangerous and addictive ingredient sold illegally as a dietary supplement. This drug is not approved by the FDA for any medical use and has caused life-threatening symptoms in patients who have used these products. This recent outbreak of critically ill patients is a reminder to the public that just because a product is easily purchased in stores and online does not mean it is safe to use and has no associated health risks.

    After seeing an unusual uptick in tianeptine calls to our poison center, we decided to investigate further and had a forensic lab test a few Neptune’s Fix products. Results concluded the presence of two synthetic cannabinoids and other ingredients such as tianeptine, kava, and two plant cannabinoids.

    Unfortunately, misleading labels and hidden ingredients are not uncommon when it comes to supplements. Potentially dangerous interactions with other medicines can cause serious and potentially fatal health effects. Call the Poison Help line at 1-800-222-1222 if you have questions or concerns about a tianeptine product or other medicine or substance. Poison control centers are available 24/7 to provide medical care and guidance.



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  • Scientists Studying Idalia in Real-Time Available to Comment on Hurricanes and Warming Oceans

    Scientists Studying Idalia in Real-Time Available to Comment on Hurricanes and Warming Oceans

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    Newswise — Is there a connection between the incidence of hurricanes and warming oceans? What do we know?

    Travis Miles and Scott Glenn, physical oceanographers at the Rutgers School of Environmental and Biological Sciences, have answers.

    The following quotes from Miles and Glenn are available to the media covering the issue.

    Quote from Miles:

    “Hurricanes draw their fuel from the oceans, intensifying over warm upper ocean features and weakening over cold ones. As our oceans warm ,we expect there to be more frequent major hurricanes with strong winds, as well as increases in precipitation. The impacts of these storms will be further enhanced with increased sea level rise. To better understand and predict the impacts of these storms, we work with a consortia of partners to collect data ahead of and beneath these powerful storms with fleets of ocean robots.”

    Quote from Glenn:

    “Motivated by our shared experience in Hurricanes Irene and Sandy, we continue to build broad partnerships to better characterize the upper ocean heat content well ahead of landfalling hurricanes, and to better understand the rapid co-evolution of the ocean and atmosphere during intense hurricane forcing. Better observations and understanding of these extreme hurricane events leads to better forecasts, and that saves lives.”

     More information:

    • Miles and Glenn are partnering with other institutions to “fly” autonomous underwater robots known as gliders under hurricanes including Hurricane Idalia. This is part of active research in the Atlantic, Gulf of Mexico, and the Caribbean to observe what happens to oceans ahead of and during hurricanes.
    • Their research is providing data to the National Weather Service to enable better hurricane forecasting models.

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  • Scientists Develop Efficient Spray Technique for Bioactive Materials

    Scientists Develop Efficient Spray Technique for Bioactive Materials

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    BYLINE: Kitta MacPherson

    Newswise — Rutgers scientists have devised a highly accurate method for creating coatings of biologically active materials for a variety of medical products. Such a technique could pave the way for a new era of transdermal medication, including shot-free vaccinations, the researchers said.

    Writing in Nature Communications, researchers described a new approach to electrospray deposition, an industrial spray-coating process. Essentially, Rutgers scientists developed a way to better control the target region within a spray zone as well as the electrical properties of microscopic particles that are being deposited. The greater command of those two properties means that more of the spray is likely to hit its microscopic target.

    In electrospray deposition, manufacturers apply a high voltage to a flowing liquid, such as a biopharmaceutical, converting it into fine particles. Each of those droplets evaporates as it travels to a target area, depositing a solid precipitate from the original solution.

    “While many people think of electrospray deposition as an efficient method, applying it normally does not work for targets that are smaller than the spray, such as the microneedle arrays in transdermal patches,” said Jonathan Singer, an associate professor in the Department of Mechanical and Aerospace Engineering in the Rutgers School of Engineering and an author on the study. “Present methods only achieve about 40 percent efficiency. However, through advanced engineering techniques we’ve developed, we can achieve efficiencies statistically indistinguishable from 100 percent.”

    Coatings are increasingly critical for a variety of medical applications. They are used on medical devices implanted into the body, such as stents, defibrillators and pacemakers. And they are beginning to be used more frequently in new products employing biologicals, such as transdermal patches.

    Advanced biological or “bioactive” materials – such as drugs and vaccines – can be costly to produce, especially if any of the material is wasted, which can greatly limit whether a patient can receive a given treatment.

    “We were looking to evaluate if electrospray deposition, which is a well-established method for analytical chemistry, could be made into an efficient approach to create biomedically active coatings,” Singer said.

    Higher efficiencies could be the key to making electrospray deposition more appealing for the manufacture of medical devices using bioactive materials, researchers said.

    “Being able to deposit with 100 percent efficiency means none of the material would be wasted, allowing devices or vaccines to be coated in this way,” said Sarah Park, a doctoral student in the Department of Materials Science and Engineering who is first author on the paper. “We anticipate that future work will expand the range of compatible materials and the material delivery rate of this high‐efficiency approach.”

    In addition, unlike other coating techniques used in manufacturing, such as dip coating and inkjet printing, the new electrospray deposition technique is characterized as “far field,” meaning that it doesn’t need highly accurate positioning of the spray source, the researchers said. As a result, the equipment necessary to employ the technique for mass manufacturing would be more affordable and easier to design.

    Other Rutgers scientists on the study included professors Jerry Shan and Hao Lin, former doctoral students Lin Lei (now at Chongqing Jiaotong University) and Emran Lallow (now at GeneOne Life Science, Inc.), and former undergraduate student Darrel D’Souza, all of the Department of Mechanical and Aerospace Engineering; and professors David Shreiber and Jeffrey Zahn, doctoral student Maria Atzampou, and former doctoral student Emily DiMartini, all of the Department of Biomedical Engineering. This work was supported by GeneOne Life Science, Inc.

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  • Eagleton Institute of Politics Experts Available to Discuss Donald Trump’s Third Indictment

    Eagleton Institute of Politics Experts Available to Discuss Donald Trump’s Third Indictment

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    John Farmer, director of the Eagleton Institute of Politics at Rutgers University, Ashley Koning, director of the Eagleton Center for Public Interest Polling, and Robert Kaufman, a distinguished professor of political science at the Rutgers School of Arts and Sciences, are available to comment on the latest indictment of Donald Trump.

    The following quotes are available for pick-up:

    John Farmer

    “The latest federal indictment of former President Trump is as significant for what it does not charge as for what it does.  In accusing the former president of obstructing the congressional process for transitioning power, conspiring to defraud the government, and conspiring to deprive the rights of others, the Special Counsel has avoided charging him with what the January 6 select committee clearly preferred: conspiracy to cause an insurrection, a charge that would have disqualified Trump, if convicted, from seeking elective office. That would have been an exceedingly difficult charge to prove, and would have reinforced the former president’s narrative that such charges would themselves have been an assault on democracy.  In my view, the charges in this indictment reflect the exercise of sound prosecutorial discretion. They do, however, raise the question: What took so long?” 

     

    Ashley Koning

    “In the short term, this latest indictment against former President Trump will simply rally his most ardent supporters, which makes up more than a third of all Republicans.  Trump’s mounting legal issues in the past several months have often given him a subsequent bump in primary polling, and his strongest competitor, Florida Governor Ron DeSantis, remains a distant second. But partisans across the board have taken the events of January 6th seriously since the beginning, and while Republicans’ views have become more complicated and divided on the issue over time, recent polling shows that an increasing number of Republicans view Trump’s involvement negatively. Piling indictments may eventually spell trouble for Trump in general with the kinds of voters he needs most: Independents and the quarter of Republicans who want anyone but him.”

     

    Robert Kaufman

    “The indictment of Donald Trump for disrupting the peaceful transfer of power in 2021 carries with it the risk of deepening the political polarization that afflicts our society. But a failure to hold him legally accountable would pose an even greater risk to American democracy, by allowing an attack on free elections to go unpunished.”

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  • People Are Falsely Denying Firearm Ownership, and It’s Not Who You Might Think

    People Are Falsely Denying Firearm Ownership, and It’s Not Who You Might Think

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    Newswise — Some firearm owners may not want researchers to know they own firearms, according to a study by the New Jersey Gun Violence Research Center at Rutgers.

    In a study published in Social Psychiatry and Psychiatric Epidemiology, researchers found that based on their answers to a variety of other questions, a group of individuals appeared as though they might be falsely denying firearm ownership when directly asked by researchers.

    While some of these individuals resemble what previous research indicated to be a typical American firearm owner (e.g., white, male), others looked quite different (racial or ethnic minority, female, living in urban environments), highlighting that the landscape of firearm ownership in the United States may be shifting.

    “Some individuals are falsely denying firearm ownership, resulting in research not accurately capturing the experiences of all firearm owners in the U.S.,” said Allison Bond, lead author of the study and a doctoral student with the New Jersey Gun Violence Research Center. “More concerningly, these individuals are not being reached with secure firearm storage messaging and firearm safety resources, which may result in them storing their firearms in an unsecure manner, which in turn increases the risk for firearm injury and death.”

    Rutgers researchers surveyed a group of 3,500 English-speaking adults who are U.S. residents. Each participant was asked if they own a firearm as well as demographic factors and questions assessing perceived threats.

    The study indicates a percentage of firearm owners may not feel comfortable disclosing their ownership status. Among those identified as potentially falsely denying firearm ownership, many were women living alone in urban environments.

    Recent research shows that since 2019, half of all new firearm owners in the U.S. identify as female and more individuals from racial and ethnic minority backgrounds have purchased firearms.

    Although researchers can’t say with certainty that individuals in the study were lying about firearm ownership, the study nonetheless highlights the importance of considering that our understanding of who owns firearms and our efforts to reach firearm owners on issues, such as secure firearm storage, may be overlooking parts of the intended audience.

     “There are several reasons some firearm owners might feel uncomfortable disclosing that they own firearms,” said Michael Anestis, executive director of the New Jersey Gun Violence Research Center and senior author of the study. “These results serve as an important reminder that we should not assume we know everything about who owns firearms and that we should ensure that our efforts to reach firearm owners can resonate with broad audiences we might not realize would benefit from the message.”

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  • Genetic Risk Information May Help People Avoid Alcohol Addiction

    Genetic Risk Information May Help People Avoid Alcohol Addiction

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    Newswise — Today’s substance use prevention efforts ignore individual genetic risk, but Rutgers research suggests DNA test results may eventually enhance prevention and treatment and improve outcomes. 

    Investigators recruited 325 college students, provided them with varying levels of information about alcohol use disorder and how genetics affect addiction risk and asked them how they would react to learning they had high, medium and low genetic tendencies toward alcoholism.

    The results provided two significant supports for eventually using real genetic risk scores in actual addiction prevention efforts. First, participants understood what those scores indicated; they recognized that higher genetic risk scores meant a higher likelihood of developing alcohol problems. Second, most participants said they would drink less and take other steps to prevent addiction if actual scores showed high risk. 

    “There are a lot of steps between the discovery of addiction-related genes and the effective use of genetic information in prevention and treatment,” said Danielle Dick, director of the Rutgers Addiction Research Center and senior author of the study published in the American Journal of Medical Genetics. “This trial paves the way for studies using real genetic data and for integrating genetic information into prevention and intervention efforts.”

    Adoption and twin studies indicate addiction risk is roughly half genetic, Dick said, but there’s no single addiction gene that’s either present or absent. Instead, there are thousands of interacting genes, so each person’s genetic risk falls somewhere on a continuum.

    Risk isn’t distributed evenly along that continuum: It’s distributed in a bell curve. A small number of people have high or low genetic risk (at the tail ends of the curve), but most people fall in the middle of the curve, she said. Knowing one’s level of genetic risk can help people make the best choices for their health and well-being. Individuals at higher genetic risk are more likely to develop problems with alcohol use, so they can take precautionary steps with their substance use.

    Despite the relative complexity of the risk calculation, study participants formed relatively accurate impressions of the risk for addiction associated with various genetic results. Future research will investigate whether other populations understand risk scores as well as the college students in this trial.

    Another important finding was that individuals reported they would experience moderate distress if they learned they were at high genetic risk for addiction. This suggests that providers should be mindful of how to return high-risk genetic results and consider accompanying this information with counseling. Encouragingly, as individuals received increasing levels of genetic risk, they also reported greater intentions to seek additional information, such as talking with a healthcare provider and engaging in harm reduction practices.   

    “Overall, the results strongly encourage the notion that real genetic risk scores may prove helpful in preventing and treating alcohol addiction,” Dick said. “Comprehension of test results was high. Psychological distress remained at manageable levels. The vast majority of individuals indicated that they’d take action to reduce their risk if they learned they were at elevated genetic risk, and, fortunately, there was no indication that people would interpret low-risk scores as an invitation to take fewer precautions.”

    Dick emphasized we still know little about how real-world genetic information will affect real-world behavior. Most known addiction genes were discovered in the past few years, and many more remain to be discovered. No commercial genetic testing service provides information about addiction risk, so very few people have ever received genuine information about their genetic tendency toward addiction. What’s more, stated intentions often differ from subsequent actions.

    “There was a hope that compelling information about elevated genetic risk would get people to change behavior, but we haven’t seen that happen for other aspects of health,” Dick said. “Initial studies suggest that receiving genetic feedback for heart disease, lung cancer, and diabetes does not get people to change their behavior. Getting people to alter their behavior is hard. Providing them with good risk information is just the first step. We then need to connect individuals to resources and support to help them reduce risk. That’s what my team is currently working on — helping people understand their addiction risk and how they can reduce that risk and avoid developing problems.”

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  • NJ Medicaid Reforms Tied to Increased Use of Opioid Addiction Treatment

    NJ Medicaid Reforms Tied to Increased Use of Opioid Addiction Treatment

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    Newswise — Reforms to New Jersey’s Medicaid program successfully spurred ongoing increases in buprenorphine prescriptions for the treatment of opioid addiction, according to a Rutgers analysis.

    Although medications such as buprenorphine effectively combat opioid addiction, less than 30 percent of potential users receive them nationwide. New Jersey sought to increase prescription numbers with three Medicaid reforms that took effect in 2019. The reforms:

    • Removed prior authorization requirements for buprenorphine prescriptions
    • Increased reimbursement rates for in-office opioid addiction treatment
    • Established regional centers of excellence for addiction treatment

    Medicaid records showed steady increases in buprenorphine prescriptions before 2019, but the rate of growth increased by 36 percent after the reforms took effect, and this increased rate of growth persisted until the end of the study period in December 2020.

    A similar trend affected caregiver behavior. The percentage of caregivers prescribing buprenorphine had been rising before the reforms took effect, but it increased faster after their implementation.

    New Jersey also experienced faster growth in buprenorphine prescriptions to Medicaid patients than did other states, the analysis reported, a strong indication that the boosts stemmed from the state’s reforms rather than some unrelated nationwide trend.

    The only disappointment came from the study’s measurement of long-term usage. The percentage of buprenorphine prescriptions that remained active for more than 180 days didn’t rise during the study period.

    “Usage remains far below the ideal where virtually everyone battling opioid addiction receives an effective medical treatment like buprenorphine,” said Peter Treitler, research project manager for the Rutgers Institute for Health, Health Care Policy and Aging Research and lead author of the analysis published in JAMA Network Open. “However, our analysis suggests these reforms may get us to that point years before we would have reached it under the previous policies.”

    Buprenorphine — a once-daily prescription pill sold in the United States as Suboxone, Zubsolv and Sublocade — works in two ways. First, it binds to the same brain cells as drugs such as opium, heroin, morphine, oxycodone and fentanyl. Once it’s in place, those other drugs struggle to dislodge it, bind to the target cells and produce addictive highs. Second, it stimulates a milder effect that reduces cravings for those other drugs and prevents withdrawal symptoms.

    Regulators once placed extra restrictions on buprenorphine prescriptions because they worried its mood-altering effects would create more addicts than it cured. These restrictions, which forced caregivers to justify each new buprenorphine prescription at length and investigated providers who prescribed the drug “too often,” led many to avoid prescribing the drug at all, said Treitler, who added Medicaid’s low reimbursement rates for office-based addiction treatment further reduced buprenorphine availability to poor patients.

    Regulators have relaxed many restrictions on buprenorphine because opioid addiction has increased. Recent research has shown buprenorphine to be both safer and more effective than previously thought. The reforms to New Jersey’s Medicaid program further reduced barriers to medication usage among its patients.

    “They looked at what obstacles were blocking the usage of a valuable drug in this particularly underserved patient population,” Treitler said. “They removed several of the biggest obstacles. And the results so far suggest they’re getting the desired results.”

    Indeed, the positive numbers seen in initiatives such as the one undertaken by New Jersey’s Medicaid program may finally be affecting the most important number of all: overdose deaths. After several decades of speedy increases, overdoses nationwide rose by just 500 in 2022.

    The trend was even better in New Jersey. Total overdose deaths fell by 232 from 2021 to 2022, and they were 93 lower in the first three months of 2023 than in the first three months of 2022.

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  • Novel Antibiotic Succeeds in Trial Against Hospital-Acquired Pneumonia

    Novel Antibiotic Succeeds in Trial Against Hospital-Acquired Pneumonia

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    Newswise — A Rutgers researcher leading a trial found that the novel combination antibiotic sulbactam-durlobactam combats dangerous pneumonia at least as well as the best currently approved treatment.

    The findings have led a unanimous expert committee to recommend that the Food and Drug Administration (FDA) approve the new drug, which could be available this summer to combat the often-fatal pneumonia strain known as carbapenem-resistant Acinetobacter baumannii–calcoaceticus complex (ABC), typically acquired in hospitals.

    “Antibiotic-resistant infections are a serious and persistent problem at healthcare facilities, and the [Centers for Disease Control] ranks ABC at the highest level on its threat list,” said Keith Kaye, chief of the Division of Allergy, Immunology and Infectious Disease at Robert Wood Johnson Medical School and first author of the trial report in The Lancet Infectious Diseases. “An estimated 8,500 hospital-acquired cases killed 700 patients and cost $280 million in 2019, so we greatly needed a breakthrough treatment like sulbactam-durlobactam.”

    The trial gave imipenem–cilastatin to 181 patients with laboratory-confirmed ABC and then randomized them to additional treatment with either sulbactam–durlobactam or the best existing treatment, an antibiotic called colistin. Mortality due to multiple causes after 28 days was 12 of 63 (19 percent) in the sulbactam–durlobactam group and 20 of 62 (32 percent) in the colistin group.

    The trial was large enough to prove that sulbactam-durlobactam prevents at least as many fatalities as colistin but not large enough to prove its superiority in this trial will persist in real-world use, though it may.

    The trial results did prove that sulbactam-durlobactam beats colistin in one crucial respect: tolerability. Kidney injury, serious adverse events and all treatment-related adverse events were significantly lower for patients who received sulbactam-durlobactam than for patients who received colistin.

    Another advantage of the novel antibiotic is dosing. All patients receive the same injectable dose of sulbactam–durlobactam. Doses of colistin in the study, on the other hand, varied with patient weight, so it’s considerably easier for providers to prescribe or administer the wrong amount.

    As its name implies, sulbactam-durlobactam combines two drugs. Sulbactam has been approved for use since 1986, but durlobactam is new and has yet to win approval. That could change soon, however. The FDA’s Antimicrobial Drugs Advisory Committee reviewed advance results of the new trial, along with earlier studies, and recommended on April 17 that the FDA approve the new combination for ABC treatment.

    FDA officials are free to reject such recommendations but almost always follow recommendations from advisory committees, which comprise independent experts on particular classes of disease and medication.

    “If all moves quickly, infected patients could begin receiving sulbactam-durlobactam as part of normal clinical care the second half of this year,” Kaye said. “Unfortunately, sulbactam-durlobactam isn’t the sort of wide-spectrum antibiotic that could prove effective in treating a wide variety of antibiotic-resistant infections, but it’s very good at treating this particularly dangerous one, and that’s a significant win.”

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  • New Jersey’s Temporary Health Care License Program Expanded Mental Health Services During Pandemic

    New Jersey’s Temporary Health Care License Program Expanded Mental Health Services During Pandemic

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    BYLINE: Nicole Swenarton

    Newswise — At least 3,700 out-of-state mental health providers utilized New Jersey’s COVID-19 Temporary Emergency Reciprocity Licensure program to provide mental health services to more than 30,000 New Jersey patients during the first year of the pandemic, according to a Rutgers study.

    The study, published in The Journal of Medical Regulation, surveyed health care practitioners who received a temporary license in New Jersey to examine the impact of the temporary licensure program on access to mental health care.

    “The New Jersey program enabled patients with already-established care to maintain care continuity and patients seeking new care to have increased access to mental health services,” said Ann Nguyen, an assistant research professor at the Center for State Health Policy at the Rutgers Institute for Health, Health Care Policy and Aging Research (IFH) and the lead author of the study.

    When New Jersey became a COVID-19 hotspot in March 2020, the state enacted the program to allow out-of-state, licensed health care providers to obtain a temporary license to provide COVID-19 and non-COVID-19 care to New Jersey residents via telecommunication technologies or in-person. According to research on temporary licensure reciprocity, at least 45 states waived or modified existing rules to allow health care providers to work across state lines through temporary licensure programs during the pandemic.

    One in five adults in the United States experience mental illness each year and 1,112,000 adults in New Jersey have a mental health condition, according to the National Alliance on Mental Illness. In February 2021, more than 42 percent of adults in New Jersey reported symptoms of anxiety or depression.

    With increasing deaths attributed to drugs, alcohol and suicide and a shortage of mental health providers throughout the U.S., Rutgers researchers said increasing access to mental health services is crucial.

    “Increased access to mental health services for even one individual, let alone over 30,000, has the potential to save lives,” Nguyen said.

    Researchers found that mental health care practitioners included in the study conversed with patients in at least 13 languages and about 53 percent of practitioners served at least one patient from an underserved racial or ethnic minority group.

    The study findings have implications for long-term licensure reciprocity mechanisms, such as interstate licensure compacts, designed to allow health care providers to have primary or home state licensure as well as either a multistate license or an option for expedited additional licenses, the researchers said.

    “As states consider enacting laws to join interstate licensure compacts, policymakers should think through the ways in which more flexible and portable licensure can enhance access to the mental health workforce, especially for patients who are historically underserved, and mitigate the workforce supply crisis,” said Nguyen.

    Coauthors of the study include Jolene Chou of the Center for State Health Policy; Elissa Kozlov, Danielle Llaneza and Molly Nowels of Rutgers of Rutgers School of Public Health; and Magda Schaler-Haynes of Columbia University Mailman School of Public Health.

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  • Achieving Prevention and Health, Rather Than More Healthcare

    Achieving Prevention and Health, Rather Than More Healthcare

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    Newswise — If more people have access to health insurance, we have to be sure the death rates of those with certain chronic conditions are decreasing.

    This is one of the statements Gregory Peck, an acute care surgeon and associate professor at Rutgers Robert Wood Johnson Medical School, will be researching on behalf of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) at the National Institutes of Health.

    Funded by NIH grants totaling more than $1 million through a recent two-year award from the New Jersey Alliance for Clinical and Translational Science (NJ ACTS), a Rutgers hub of the National Center for Advancing Translation Science, and now a four-year award from the NIDDK, Peck is on average one of just two critical care surgeons funded nationally annually creating new models of health for NIH consideration.

    Peck recently published two studies investigating death rates for gallstone disease, a disease of the abdomen that causes right-sided belly pain after eating, which share risk factors with other deadly diseases. His study, published in Gastro Hep Advances, found that between 2009 and 2018 the number of deaths of people in New Jersey with diagnosed gallstone disease (1,580) remained steady and did not improve, and that deaths in Latinos ages 65 and older potentially increased.

    His study in the Journal of Surgical Research found that after Medicaid expansion in 2014 as compared to before, the amount of emergency surgery to remove the gallbladders for gallstone disease decreased in the state overall, but increased in people with Medicaid. While fatality from gallbladder removal surgery decreased for those 65 or older, there was increased death from surgery in the younger population and a trend of more death in the population with Medicaid. Further, the relatively decreased amount of gallbladder removal surgery occurring in ambulatory outpatient care centers did not necessarily help this.

    Peck discusses the implications of the findings on a new shift in healthcare to prevention model.

    Why did you focus on gallstone disease?

    As a metabolic disease, gallstone disease is also linked to heart disease, cancer, diabetes, obesity and a sedentary lifestyle. In fact, heart disease, which is the No. 1 killer in America, and gallstone disease, which is the No. 1 digestive disease requiring surgery in America, share the risk factors of high levels of bad cholesterol type and obesity.

    How do these studies inform public policy?

    The amount of people dying with gallstone disease – most of whom require surgery – over the past decade has not gotten better. That’s 160 people a year who still are dying from a preventable death such as gallstone disease. Making progress is what this type of epidemiologic study focuses on, and concerningly, we might not have made good progress.

    If Medicaid expansion didn’t positively affect the death rate of people with gallstone disease and we see it increase specifically in older Latino populations, we need to be asking if we are helping people of color and those who live in communities with lower socioeconomic status improve health or treating them sooner to prevent emergency surgery and especially decreasing death from emergency surgery. Insurance expansion is certainly needed, but we have to ensure the action specific pieces of policy impact the population requiring surgery in a patient-centered way.

    The real goal is preventing the disease from even occurring. When we pass public health policy, we need to advocate for preventive care that reaches people through their community. Right now, the findings show that we might just be providing people with insurance cards who find themselves still needing to use the emergency department. Instead, that insurance should help them visit their primary care doctor, who can help them make changes like decreasing their bad cholesterol levels, which contribute to gallstone disease, and help them access care in ambulatory surgery centers sooner.

    We need to cultivate preventive healthcare rather than ballooning the investment in emergency healthcare, which does not solve current inequities.

    What other steps to improve access to care should be taken?

    We propose a novel population health approach that shifts from the reactive treatments of emergency disease to proactive prevention. One place to start is increasing access to appropriate outpatient elective healthcare for underrepresented groups with barriers to preventive care, such as by increasing health insurance that incentivizes the behaviors toward improved health. A first step for my research group is to focus on diseases that currently require as much emergency as elective care, such as gallstone disease, and understand this by understanding who presents to the hospital, as to dial this back into the community level, to decrease hospital care.

    In addition, in primary care, laboratory, radiology or ambulatory care settings we need to improve communication with people with low English proficiency – especially how well prevention is explained in a patient’s primary language. Language barriers might also prevent them from understanding the importance of cholesterol or blood pressure control over the one, two and three decades of life, or how they find access to diagnostic tests or treatment needed earlier.

    How is Rutgers working to increase primary care knowledge in underserved communities?

    Shawna Hudson, the co-director of community engagement for NJ ACTS, and my research mentor, is researching how representatives rooted in the community can help healthcare providers and researchers better understand how we can use community engagement to involve people in a communities’ preventive care as to decrease risk factors for chronic disease before they need hospital-based care and, more importantly, emergency surgery.

    One initiative is the Community Engagement Virtual Salons, which help researchers and health care providers at NJ ACTS engage with patients and community members about how biomedical and clinical research leads to action through understanding disease and then enacting policy. In these sessions, the public serves as experts to provide feedback from a community perspective. This allows the medical profession to build relationships with community partners and increase the culturally sensitive participation of hard-to-reach populations.

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  • Fungus/Fungal Disease Expert Can Comment on Outbreak at Healthcare Facilities

    Fungus/Fungal Disease Expert Can Comment on Outbreak at Healthcare Facilities

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    Darin Wiesner, a professor at Rutgers New Jersey Medical School who studies fungal disease, can comment on the surge of drug-resistant fungal infections at medical facilities across the US.

    The following quotes from Wiesner are available to journalists covering the issue.

    • Several aspects of C. auris should be concerning to immunocompromised patients, including the elderly and chronically ill, that receive care in a healthcare setting.
    • The fungus can access parts of an immunocompromised patient’s body that cause serious disease and make the treatment extremely difficult. C. auris is resistant to a few of the already small list of available antifungal medications.
    • At-risk populations congregate at healthcare facilities, C. auris tends to accumulate in areas that sick patients frequent, and the cycle repeats.
    • C. auris can grow on the skin and in nasal cavities of caregivers, as well as on surfaces of equipment and furniture at healthcare facilities.
    • Currently, there are only three classes of anti-fungal drugs. C. auris is completely resistant to one of them (azoles) and is evolving resistance to the others (polyenes and echinocandins). Like multi-drug resistant bacteria (e.g., MRSA), C. auris poses a serious risk of depleting treatment options and, consequently, increasing both the cost of treatment and the mortality of infected patients. Thankfully, developing new anti-fungal drugs is a very active area of investigation among academic researchers.

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  • “Y-Ball” Compound Yields Quantum Secrets

    “Y-Ball” Compound Yields Quantum Secrets

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    BYLINE: Kitta MacPherson

    Newswise — Scientists investigating a compound called “Y-ball” which belongs to a mysterious class of “strange metals” viewed as centrally important to next-generation quantum materials have found new ways to probe and understand its behavior.

    The results of the experiments, aided by the insights of theoretical physicists at Rutgers, could play a role in the development of revolutionary technologies and devices.

    “It’s likely that that quantum materials will drive the next generation of technology and that strange metals will be part of that story,” said Piers Coleman, a Distinguished Professor at the Rutgers Center for Materials Theory in the Department of Physics and Astronomy at the Rutgers School of Arts and Sciences and one of the theoreticians involved in the study. “We know that strange metals like Y-ball exhibit properties that need to be understood to develop these future applications. We’re pretty sure that understanding this strange metal will give us new ideas and will help us design and discover new materials.”

    Reporting in the journal Science, an international team of researchers from Rutgers, the University of Hyogo and the University of Tokyo in Japan, the University of Cincinnati and Johns Hopkins University described details of electron motion that provide new insight into the unusual electrical properties of Y-ball. The material, technically known as the compound YbAlB4, contains the elements ytterbium, aluminum and boron. It was nicknamed “Y-ball” by the late Elihu Abrahams, founding director of the Rutgers Center for Materials Theory.

    The experiment revealed unusual fluctuations in the strange metal’s electrical charge. The work is groundbreaking, the researchers said, because of the novel way the experimenters examined Y-ball, firing gamma rays at it using a synchrotron, a type of particle accelerator.

    The Rutgers team – including Coleman, fellow physics professor Premala Chandra and former postdoctoral fellow Yashar Komijani (now an assistant professor at the University of Cincinnati) – have spent years exploring the mysteries of strange metals. They do so through the framework of quantum mechanics, the physical laws governing the realm of the ultra-small, home of the building blocks of nature such as electrons.

    Analyzing the material using a technique known as Mossbauer spectroscopy, the scientists probed Y-ball with gamma rays, measuring the rate at which the strange metal’s electrical charge fluctuates. In a conventional metal, as they move, electrons hop in and out of the atoms, causing their electrical charge to fluctuate, but at a rate that is thousands of times too fast to be seen by Mossbauer spectroscopy. In this case, the change happened in a nanosecond, a billionth of a second.

    “In the quantum world, a nanosecond is an eternity,” said Komijani. “For a long time, we have been wondering why these fluctuations are actually so slow.” “We reasoned,” continued Chandra, “that each time an electron hops into an ytterbium atom, it stays there long enough to attract the surrounding atoms, causing them to move in and out. This synchronized dance of the electrons and atoms slows the whole process so that it can be seen by the Mossbauer.”

    They moved to the next step. “We asked the experimentalists to look for these vibrations,” said Komijani, “and to our delight, they detected them.”

    Coleman explained that when an electrical current flows through conventional metals, such as copper, random atomic motion scatters the electrons causing friction called resistance. As the temperature is raised, the resistance increases in a complex fashion and at some point it reaches a plateau.

    In strange metals such as Y-ball, however, resistance increases linearly with temperature, a much simpler behavior. In addition, further contributing to their “strangeness,” when Y-ball and other strange metals are cooled to low temperatures, they often become superconductors, exhibiting no resistance at all.

    The materials with the highest superconducting temperatures fall into this strange family. These metals are thus very important because they provide the canvas for new forms of electronic matter – especially exotic and high temperature superconductivity. 

    Superconducting materials are expected to be central to the next generation of quantum technologies because, in eliminating all electrical resistance, they allow an electric current to flow in a quantum mechanically synchronized fashion.  The researchers see their work as opening a door to future, perhaps unimaginable possibilities.

     “In the 19th century, when people were trying to figure out electricity and magnetism, they couldn’t have imagined the next century, which was entirely driven by that understanding,” Coleman said. “And so, it’s also true today, that when we use the vague phrase ‘quantum materials,’ we can’t really envisage how it will transform the lives of our grandchildren.”

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  • Inmates With Opioid Addiction Report Peer Navigators Are Crucial for Successful Community Reentry

    Inmates With Opioid Addiction Report Peer Navigators Are Crucial for Successful Community Reentry

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    Newswise — Recently incarcerated people with opioid use disorder have trust in working with peer support specialists who recovered from addiction and faced similar life experiences, according to a Rutgers study.

    The study, published in the journal Psychiatric Services, found that peer support specialists were most valued for providing emotional and community-based addiction recovery support as well as housing and employment information — crucial when going back into the community.

    More than half of people incarcerated in state prisons have been diagnosed with a substance use disorder, according to the U.S. Department of Justice. They are most vulnerable in the months following their release, when they are at high risk of unemployment, homelessness, recidivism and overdose.

    “The risk of a fatal drug overdose in the two weeks after release is 129 times that of the general population, in part because of the high risk of relapse and the loss of drug tolerance while incarcerated,” said Margaret Swarbrick, associate director of the Center of Alcohol & Substance Use Studies at Rutgers, research professor at the Graduate School of Applied and Professional Psychology and an author of the study.

    The researchers interviewed 39 adult inmates diagnosed with an opioid use disorder who worked with peer support specialists upon their release from a New Jersey state prison between July 2020 and April 2021. Thirty completed a follow-up interview about four months later.

    They found that participants appreciated working with someone with a shared life experience with whom they could establish a trusting relationship. However, they reported that policy barriers to recovery and community reintegration presented challenges to meeting certain needs, such as housing, food, employment and access to timely medical and recovery services, even with the peer navigator’s assistance.

    Participants reported the peer support specialists were most valued for providing emotional support and housing and employment information and for navigating barriers to medical and community-based treatment. This was especially true for people with a conviction for drug distribution charges, which precludes access to resources for housing and employment, according to Michael Enich, an M.D.-Ph.D candidate at Rutgers Robert Wood Johnson Medical School, who reported on the findings.

    “Studies have shown that trained peer support specialists who have experienced addiction, incarceration or both, who assist newly released offenders significantly improve the success rates of their reentry into society, especially when it comes to mental health treatment and sobriety,” said Enich. “However, few studies have examined the role of peer services for substance use disorders during the early months after prison release.”

    Many participants viewed their peer navigators as role models who have overcome similar challenges, which was valued especially when they felt at risk of relapse, said Stephen Crystal, director of the Center for Health Services Research at Rutgers Institute for Health, Health Care Policy and Aging Research and an author of the study. “Having someone who was there for them ‘no matter what’ and whom they could call at any time was the most important aspect of the program as it gave them a sense of security,” said Crystal, who is also Board of Governors Professor at Rutgers School of Social Work.

    The participants reported the most effective peer health navigators were empathetic, open-minded and good listeners.

    The authors said more research is needed to rigorously examine the long-term impact of peer services on factors such as overdose reduction, treatment engagement and sustained recovery.

    Other Rutgers researchers involved in the study are Peter Treitler, Leigh Belsky and Micah Hillis.

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  • Health Care Providers Rarely Ask Patients About Access to Firearms

    Health Care Providers Rarely Ask Patients About Access to Firearms

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    Newswise — Health care providers rarely ask patients if they have access to firearms in their home – a question that could diminish the risk of serious injury or death and encourage conversations about secure firearm storage, according to a Rutgers study.

    However, according to a study in Preventive Medicine, led by the New Jersey Gun Violence Research Center at Rutgers, health care providers rarely screen their patients for firearm access.

    Researchers surveyed 3,510 English-speaking adults in five states: Colorado, Minnesota, Mississippi, New Jersey and Texas, asking if a health care provider had ever asked them whether they have access to firearms.

    They found that 17.1 percent of participants had been asked by a health care provider about firearm access. This number was largely consistent across groups, with 20.1 percent of those with children 17 years old or younger, 25.5 percent of those with a history of mental health treatment and 21.4 percent of firearm owners ever having been screened for firearm access.

    “Although we know that firearm access increases the risk for fatal injury for everyone in the home, health care providers are rarely asking about firearm access,” said Allison Bond, a doctoral student at the New Jersey Gun Violence Research Center and the lead author of the study. “In order to prevent these injuries and deaths, healthcare providers need consider adding screening for firearm access into standard practice so that they are better positioned to then provide resources on secure firearm storage to the families that would most benefit from that information.”

    Researchers also examined which factors were associated with greater odds of having been screened by a health care provider for firearm access.

    They found that individuals with a lifetime history of suicidal thoughts, men, those who identified as white, parents with children 17 years old or younger living in the home, those with a history of mental health treatment and firearm owners were more likely to have been screened.

    Among firearm owners, those with children in the home ages 17 or younger and those with a history of mental health treatment were more likely to have been screened. Even among groups with greater odds of having been screened, the majority of individuals had never been asked about firearm access.

    “Given these results, it appears that screening is more likely among certain health care providers, like pediatricians and mental health care providers,” said Michael Anestis, executive director of the New Jersey Gun Violence Research Center, an associate professor in the Rutgers School of Public Health and senior author of the study. “It may also be that health care providers are often relying upon their sense of who is most likely to own a firearm when making a decision whether or not to ask.”

    “The problem with that, however, is that the demographics of firearm ownership have changed in the past few years and many of those at greatest risk for firearm injury or death never present in specialized mental health care settings,” said Anestis. “We need health care providers to broaden their vision of the role of firearm access to ensure they can help the greatest number of people.”

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  • Rutgers Researchers to Study the Impact of Multiple Health Conditions on Medication Outcomes in Older Adults

    Rutgers Researchers to Study the Impact of Multiple Health Conditions on Medication Outcomes in Older Adults

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    Newswise — The National Institutes of Health has awarded Rutgers a $3.5 million grant to conduct a five-year study exploring the impact medications have on older adults with multiple medical conditions.

    The goal of researchers from Rutgers Center for Pharmacoepidemiology and Treatment Science (PETS) is to provide patients with multiple chronic conditions, caregivers and health care providers with information needed to make informed treatment decisions.

    “Unfortunately, most clinical trials of medications do not include patients with multimorbidity, which means that there is little data available about the risks and benefits of medications in this population,” said Chintan Dave, assistant director at PETS and the principal investigator of the National Heart, Lung and Blood Institute grant-backed project. “This lack of information makes it difficult for health care providers to make informed decisions about treating patients with multiple medical conditions.”

    Multimorbidity is a common issue for older adults, according to researchers. In the U.S., more than two thirds of adults over the age of 65 have multiple chronic conditions, which can lead to higher health care costs and increased risk of negative health outcomes, including death.

    “With over 36 million older adults in the U.S. affected by multimorbidity, this is a pressing issue that requires immediate attention,” said Dave, who also is a core faculty member of the Rutgers Institute for Health, Health Care Policy and Aging Research (IFH) and an assistant professor with Rutgers Ernest Mario School of Pharmacy.

    Dave and his colleagues will use data from more than 23 million patients to learn how having multiple conditions affects the benefits and risks of medications, representing the first effort to systematically evaluate the impact of multimorbidity on medication related outcomes. Specifically, researchers will examine medication use and outcomes in three highly prevalent chronic conditions: Type 2 diabetes, atrial fibrillation and atherosclerotic cardiovascular disease.

    Coinvestigators involved in the study include Brian Strom, the chancellor of Rutgers Biomedical and Health Sciences; Tobias Gerhard, interim director of IFH and director of PETS; Jason Roy, a professor of biostatistics and chair of the Department of Biostatistics and Epidemiology at the Rutgers School of Public Health; Soko Setoguchi, a core faculty member at PETS and IFH, professor of medicine at Rutgers Robert Wood Johnson Medical School and professor of epidemiology at Rutgers School of Public Health; and Melissa Wei, an assistant professor of medicine in residence at the David Geffen School of Medicine at University of California, Los Angeles.

    The grant was supported by the National Heart, Lung, And Blood Institute of the National Institutes of Health under Award Number R01HL163163. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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  • State of the Union Coverage: Experts Available

    State of the Union Coverage: Experts Available

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    Rutgers University–New Brunswick faculty experts are available before, during and after President Biden’s State of the Union address on Feb. 7. For interviews, please reach out to the listed contacts.

    David Greenberg, @republicofspin

    Expert on U.S. political and cultural history, including the presidency, campaigns and elections, political parties, political ideas, public policy, and a contributing editor to Politico. Greenberg can discuss past States of the Union, presidential history and rhetoric, and the impact Biden’s speech may have on current divisions in the United States. Professor of history and of journalism and media Studies.

    Ross Baker, @Rosbake1

    Expert in U.S. government, legislative politics, Congressional issues and the presidency. Baker can discuss coronavirus relief, bipartisanship and polarization in the House and Senate, and passing legislation. Distinguished Professor in political science.

    John J. Farmer, Jr.

    Expert on U.S. politics, redistricting, law, security and community protection for vulnerable populations. Farmer can discuss the U.S. Capitol riots, national security and how President Biden is working to bridge the partisan divide. Director of Rutgers’ Eagleton Institute of Politics, Rutgers’ Miller Center for Community Protection and Resilience, and University professor of law.

    Ashley Koning, @AshleyAKoning

    Expert on U.S. public opinion, survey design, polling trends and mass political behavior. Koning can discuss President Biden’s approval rating and public opinion on COVID-19, the vaccination rollout and coronavirus relief, and the national political dynamic and polarization. Director of Rutgers’ Eagleton Center for Public Polling and Eagleton assistant research professor.

    Saladin Ambar, @dinambar

    Expert on race and U.S. politics, the president and American governors. Eagleton associate professor of political science, senior scholar at the Eagleton Center on the American Governor.

    John Weingart

    Expert on U.S. politics and government, including history of relevant past elections, and the administrative functioning and inclusion of the public in government operations. Associate director of Rutgers’ Eagleton Institute of Politics and director of the Eagleton Center on the American Governor.

    Kristoffer Shields

    Shields researches and analyzes the office of the governor in a national context. He is an Eagleton Assistant Research Professor and Historian at the Eagleton Center on the American Governor.

    Debbie Walsh, @DebbieWalsh58 Expert on the modern history of women in politics, progress in political representation, women and the political parties, and campaign messaging for women candidates. Director of the Center for American Women and Politics, a unit of the Eagleton Institute of Politics at Rutgers.

    Jean Sinzdak Expert on milestones in women’s political history, candidate recruitment and training, and state legislatures. Associate director of the Center for American Women and Politics, a unit of the Eagleton Institute of Politics at Rutgers.

    Kelly Dittmar, @kdittmar Expert on gender and campaigning, women and institutions of government, current data and analysis on women’s representation, and women voters. Director of Research and Scholar of the Center for American Women and Politics, a unit of the Eagleton Institute of Politics at Rutgers.

    Kira Sanbonmatsu Sanbonmatsu’s research interests include gender, race/ethnicity, parties, public opinion, and state politics. Professor of political science and senior scholar at the Center for American Women and Politics.

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  • What Does the Debt-Ceiling Fight Mean to You?

    What Does the Debt-Ceiling Fight Mean to You?

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    Hitting the debt ceiling – how much money the federal government can borrow to pay its bills – could lead to economic catastrophe if the situation isn’t handled appropriately, said John Longo, a professor of professional practice at Rutgers Business School.

    The U.S. government is borrowing up to the $31.4 trillion debt limit, which has prompted Senate and House discussions on whether to raise it or risk economic disaster.

    Finance and economic expert Longo explained what this means for the average taxpayer and who is the most vulnerable if there is a default.

    What is the debt limit and why does it have to be raised?

    The federal government runs a persistent budget deficit. That is, its annual inflows, which largely come from taxes and fees, are less than its yearly spending. The U.S. Constitution allows Congress to control the federal government’s finances. Therefore, it must approve federal debt increases, which may be viewed as the sum of our country’s annual deficit from its founding until the present. Unless Congress approves increasing the debt ceiling, there is a risk that the U.S. government cannot pay its bills, which would have severely negative economic implications. 

    So what does this mean for the average taxpayer?

    The odds are that it will mean nothing for the average taxpayer in the short run since the debt ceiling has been extended roughly a hundred times since it was instituted in 1917. If the taxpayer receives some payment from the federal government, there may be a delay in receiving a promised payment. 

    If the debt ceiling is not extended and the federal government defaults on its U.S. Treasury obligations, it may result in a crash in financial assets, severely impacting most taxpayers. In the long run, taxes may increase, or federal government spending must come down. This is because there is growing frustration on both sides of the political aisle with regularly facing the debt-ceiling issue. 

    Who will be most affected?

    The immediate effect will be on those reliant on the federal government for payments. There may be a delay in receiving promised payments or receiving less than what they are owed. First in line is likely external government vendors or contractors. Then it can get quite serious since U.S. military members and those receiving federal government entitlement benefits won’t get paid on time. These entitlement beneficiaries include those receiving payments from programs that support Social Security, Medicaid and food and housing assistance. Overall economic spending would be reduced, likely pushing the U.S. economy into a recession. 

    Perhaps most seriously, if the U.S. Treasury does not meet its debt obligations, it would result in a default on trillions of dollars of assets. These assets, currently considered high investment grade, would turn into “junk” bonds overnight and may result in a cascade of selling across many financial assets. The U.S. Treasury can utilize accounting gimmicks to postpone the day of financial reckoning for several months, but it cannot go on indefinitely. Congress knows these issues and usually agrees to a deal at the last minute. Since the federal government almost always runs a budget deficit, it basically amounts to kicking the can down the road, which is why the debt-ceiling issue resurfaces every year or two. 

    What does the fight over the House Speaker foreshadow about the debt-ceiling fight? 

    The majority of the House and Senate must approve the debt-ceiling expansion. The current speaker of the House, Kevin McCarthy, was barely elected after more than a dozen failed elections. A sizable contingent of those opposing his nomination want greater fiscal austerity and said they would not vote to raise the debt ceiling. Some congresspeople want concessions, primarily in the form of spending cuts or increased taxes, to vote for an extension of the debt ceiling. In short, there is often a lot of political wrangling going on behind the scenes before the limit is increased, yet again. 

    Why are politicians even fighting about this in the first place? 

    Congress controls the federal government’s purse strings. They won’t let the federal government run an unlimited budget deficit, so the debt-ceiling issue is likely to resurface every year or so. It is highly unlikely that the federal government will run a persistent budget surplus since most congresspeople like to spend money. An aspirational goal may be to have a balanced federal budget in the long run. Several states have operated on this model, so it is not an impossible task.

    However, I think the odds are we will continue to do what has happened since the current model was adopted in the early 1900s. We will continue to face this issue every year or two until there is bipartisan agreement on a more rational model. 

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  • Why We Need Sustainability to Achieve Public Health

    Why We Need Sustainability to Achieve Public Health

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    Newswise — Sustainability has been a hot topic for many years, with people adopting practices such as recycling, repurposing, and other environmentally friendly acts.

    But sustainability is so much more than this and includes the health and wellbeing of people and society at large. Universities play a critical role in advancing the cause. Working to promote sustainability can influence effect and amplify change beyond the institution, said Wendy Purcell, professor at the Rutgers School of Public Health, whose work focuses on how universities and higher education can help to tackle challenges such as the climate crisis, food insecurity and pandemic risk.

    Purcell’s new book on the subject, The Bloomsbury Handbook of Sustainability in Higher Education, which comes out in February, talks about what sustainability means and how universities are key to sustainable development.

     What does sustainability mean?

    Sustainability is about people, planet, and shared prosperity: It’s about stewarding natural, human, and cultural resources for the benefit of all – now and into the future. It’s an agenda firmly rooted in equity and social justice across generations, which is reflected in the Sustainable Development Goals set out by the United Nations in 2015. These global goals represent the nearest thing we have to a strategy for our world. Seventeen of the goals were agreed upon by 193 countries with the aim to create a world that leaves no-one behind.

    How are sustainability and public health connected?

    The intersection between planetary health and human health is profound – from the air we breathe and the food we eat, to the homes we live in and the work we do.

    The Lancet Countdown tracks the connections between public health and climate change and makes for sobering reading, from the spread of infectious diseases to rising food insecurity. My recent paper documents the health impacts of extreme climate events – from heat waves to smoke from wildfires – and shows how climate change is multiplying health risks and exacerbating inequalities in society.

    As well as affecting individual health, sustainability is about health systems and the social factors that affect health like housing, education, and decent work.

    Why is sustainability a priority for the Rutgers School of Public Health?

    Public health is interdisciplinary, bringing together different disciplines to focus on the health of people and populations. The Rutgers School of Public Health is the ideal place to explore questions that span the disciplines and develop solutions that connect the environment, society, and the economy using the lens of health.

    Healthy planet and healthy people make for a healthy society and economy. One of the United Nation’s Sustainable Development Goals, SDG4 ‘Quality Education,’ shows that education for sustainable development is about sustainable lifestyles, human rights, gender equality, promotion of a culture of peace and nonviolence, global citizenship and appreciate of cultural diversity – all of which resonate strongly with the school’s mission, vision, and values.

    I am truly excited to be part of Rutgers, an anchor institution in New Jersey and central to the state’s agenda for health for all, economic inclusion, and equity.  

    What is being done at the Rutgers School of Public Health?

    A recent study shows student interest in sustainable development rose 18 percent year-on-year with demand outstripping the supply of programs by 2.5 times. Students know that the pursuit of sustainability is critical to achieving a more inclusive society, a healthier planet, and a more balanced economy.

    The task now is for universities and colleges to step up to meet this increased demand – and we plan to do just that.

    I’m developing a suite of new courses related to sustainability, climate, and health at the Rutgers School of Public Health, New Jersey’s only accredited school of public health. I’m also developing new programs for those in business and organizational settings who need solutions to the problems they are facing every day. At Rutgers, the Rutgers Climate Action Group is championing climate justice, civic responsibility, and actionable scholarship.

    You can learn more about the school’s efforts around sustainability by visiting the Rutgers School of Public Health’s annual tent on Rutgers Day.

    How can college students contribute to sustainability?

    Working to ensure that all students are both sustainability and climate literate is part of the responsibility of any university to help set up its graduates and learners for lifelong success in a world hungry for solutions to the grand challenge of our day.

    Too often, sustainability is a marginal activity and not mainstreamed into programs of study. This leaves students having to find opportunities outside the classroom to pursue their interests in helping create a more just and inclusive world. I’d encourage students to get involved through their courses and activities on campus, working with their university to promote sustainability initiatives and campaigns. The 17-book project on higher education and the Sustainable Development Goals I am leading as series editor places the student voice at the heart of this agenda for change.

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  • Oncology Researcher Joins Rutgers Global Health Institute

    Oncology Researcher Joins Rutgers Global Health Institute

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    Newswise — Wilfred Ngwa, a global oncology researcher and medical physics expert who is developing technologies that integrate with radiation therapy to reduce cancer treatment times and costs, has joined Rutgers Global Health Institute.

    Ngwa, who is a Rutgers Presidential Faculty Scholar and a professor of global health at the institute, also holds an appointment as a professor in the Department of Radiation Oncology at the Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School.

    The broad aim of Ngwa’s research and global collaboration is to increase access to cancer treatment and reduce health disparities, particularly in low- and middle-income countries. He leads a research group that is developing low-cost approaches and technologies that can substantially reduce treatment times and costs and that can be implemented in resource-poor settings.

    One such technology incorporates artificial intelligence and smart radiotherapy biomaterials, such as nanoparticle drones that can be injected intravenously and will emit missile-like electrons when activated by photon beams during radiation therapy. This process is designed to increase damage to cancerous tumors while minimizing toxic effects on body tissues. This technology also can be programmed to sustainably deliver cancer-fighting immunotherapy drugs in resource-effective and measurable ways. This research is supported by the National Institutes of Health and industry partners and is in clinical translation, with multisite clinical trials on track to begin in 2023.

    Ngwa’s overall research program is designed to address many types of cancer, and he is leading studies related to treating prostate, breast, and cervical cancers in Nigeria, South Africa, Tanzania and the United States.

    “Expanding our multicenter clinical trials to additional U.S. and African institutions will be a focus of my research at Rutgers. Implementation research also will be a priority, so that we can turn knowledge into real-world actions that will improve health care delivery and global health,” Ngwa said. “By building on my work with radiotherapy and the use of advanced information and communication technologies in oncology care, I look forward to developing a vibrant research program at Rutgers.”

    Ngwa is widely regarded as an expert on public health policy and cancer control in sub-Saharan Africa. Since 2019, he has been the chair of The Lancet Oncology commission on cancer in sub-Saharan Africa, which in the spring published its report about the rapidly escalating cancer burden in this resource-poor area of the world. Ngwa is an external adviser to the U.S. presidential administration’s Cancer Cabinet, convened by President Joe Biden to help establish and make progress on the administration’s reignited Cancer Moonshot initiative, and he is a co-chair of the U.S. Cancer Moonshot 2.0 Lancet Oncology commission. He is editor of IOP Publishing’s scientific series in global health and radiation oncology and an editorial board member for Journal of Global Oncology, Frontiers in Oncology and ecancermedicalscience.

    As the founding director of the Global Health Catalyst Summit, Ngwa leads a collaborative that convenes an annual summit and other events designed to catalyze high-impact international collaborations and initiatives to eliminate health-related disparities in the United States and globally. An ongoing project that originated via a summit is C4: Comprehensive Cancer Center in the Cloud, an artificial intelligence-driven platform that Ngwa is developing with multidisciplinary partners to increase access to cancer care, research and education regardless of geographic location.

    Ngwa is originally from Cameroon, where he studied physics and computer science at the University of Buea, receiving a bachelor of science degree. He earned his master’s and doctoral degrees from University of Leipzig in Germany then completed postdoctoral education and training in radiation oncology at MD Anderson Cancer Center at the University of Texas and at Brigham and Women’s Hospital, Dana-Farber Cancer Institute and Harvard Medical School.

    Ngwa previously was an associate professor of radiation oncology and molecular radiation sciences at Johns Hopkins University’s School of Medicine and Sidney Kimmel Comprehensive Cancer Center. He also holds an appointment as a distinguished professor of public health at the ICT University, based in Cameroon.

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  • Rutgers Philosopher Argues for a “Realistic Blacktopia”

    Rutgers Philosopher Argues for a “Realistic Blacktopia”

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    A philosopher weighs in on the rise of voter suppression, anti-protest legislation and efforts to roll back racial progress

    Fifty-six years after Martin Luther King, Jr., told students at Southern Methodist University that “we have come a long way but we still have a long, long way to go,” Rutgers philosopher Derrick Darby is making a similar argument.

    In his new book, A Realistic Blacktopia: Why We Must Unite to Fight, Darby draws on King, W. E. B. Du Bois and the black radical tradition to explore how to make progress in the antiracist struggle.

    Darby, a Henry Rutgers Distinguished Professor of Philosophy and founding director of the Social Justice Solutions Research Collaboratory, discusses alliances, voting rights, affirmative action and the limits of racial remedies.

    Martin Luther King Jr. argued that voter suppression undermines a citizen’s right to make choices, undermining their dignity. Equal voting rights is something King strived to get the nation to do. What would he think of voter access today?

    The forms of voter suppression seen across America would have been a major concern for Dr. King. Tactics include tougher photo identification laws, closing or reducing polling places, attempts to eliminate Sunday early voting and making vote by mail more difficult.

    It is doubly shameful in a democracy like ours that values equality and justice when it creates a significant burden for groups such as communities of color, seniors, young people and the poor.

    Members of these groups tend to have more limited opportunities to vote because of voter suppression and long wait times on Election Day. We saw this in Georgia in 2020 and during the recent midterm elections. During the 2020 election, Georgia criminalized the distribution of water or snacks to people waiting to vote. Dr. King would have been appalled. He would have supported efforts to make voting easier – including issuing a federal voting ID card, enacting automatic voter registration, expanding early voting and ensuring greater access to polling places and multilingual ballot support.

    During the civil rights movement, King recognized building interracial alliances to address social problems that disproportionately affected African Americans. What were some examples?

    Dr. King believed addressing voter rights and civil rights concerns was crucial to getting America to live up to its promises and potential. Relying on the power of nonviolence direct action by interracial alliances of people committed to these and other causes was vital to this effort. The 1963 March on Washington for jobs and freedom is the most well-known example of the power of such alliances.

    King and other prominent civil rights organizers such as Bayard Rustin believed freedom wasn’t just about racial and other forms of discrimination. It was also about freedom from poverty, hunger, joblessness, illiteracy, preventable illness, etc. Because these issues don’t recognize racial divisions, they provide a broader basis for building alliances.

    King’s support of striking sanitation workers in Memphis and his efforts to build the Poor People’s Campaign are examples of objectives that demanded broader alliances.   

    Although America is awash in race and race-relations discussions, antiracist books are everywhere and diversity seminars are hot tickets. Many efforts are underway to roll back the racial progress clock. What are some of these efforts?

    Following the senseless murder of George Floyd by the police, there was a massive public outcry and scores of organized Black Lives Matter protests around the nation. Protesters – a large and diverse group representing different races, ethnicities, sexual orientations, classes and religions – took to the streets to demand social justice and end police brutality. These protests sought racial progress.

    Some state legislators proposed, and in some cases enacted, anti-protest legislation in response. Alabama enacted a law in 2021 that upgraded obstructing a sidewalk during a protest to a misdemeanor punishable by up to one year in jail. Mississippi has a pending bill that would make “violent or disorderly assembly” of seven or more people a felony and would apply to peaceful protesters who pose a danger to property, personal injury or obstruct law enforcement.

    In your opinion, affirmative action was once a way to provide African Americans with better educational opportunities, but that time has passed. What do you suggest in its place?

    Affirmative action – understood as a race-specific remedy – is unconstitutional. Existing efforts to promote diversity in schools have had to show that considering race as a plus factor among other factors is part of a holistic approach to ensuring diversity. The U.S. Supreme Court will soon rule on whether this practice, is permissible. I’m not optimistic about the outcome.

    Various alternatives have been proposed, such as targeting socioeconomic diversity and targeting top students in districts for admissions but the jury is out on whether they can achieve the relevant kind of diversity without triggering court challenges.

    Whatever the outcome, greater investment in preparing kids from disadvantaged communities and providing support for families seeking opportunities for educational enrichment for their children is part of a broader solution.

    You argue securing racial justice in America calls for “big tent” remedies. That is, antiracists must build partnerships among populations interested in issues that impact them collectively. Could you explain further with an example?

    Big-tent remedies involve paying attention to matters of economic justice in addition to racial justice and remaining mindful of their interconnectedness.

    Marginalized populations are disproportionately impacted by health crises such as COVID-19 because they typically have no health care or poor care. They typically work low-wage jobs with no benefits, sick leave and time off. Individuals in these populations also can’t work from home, as many work in the service industry. They must rely on public transportation, which disproportionately increases the risk of exposure and illness in poorer black and brown communities.

    Health concerns, getting paid decent wages, better working conditions, affordable child care and educational opportunities are among the issues of broader concern.

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    Rutgers University-New Brunswick

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