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Tag: Research

  • Researchers Are Using AI to Find New Alzheimer’s Risk Factors

    Researchers Are Using AI to Find New Alzheimer’s Risk Factors

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    Brain experts have a pretty good handle on some of the major risk factors that contribute to Alzheimer’s—from a person’s genes to their physical activity levels, how much formal education they’ve received, and how socially engaged they are.

    But one promise of AI in medicine is that it can spot less obvious links that humans can’t always see. Could AI help uncover conditions linked to Alzheimer’s that have so far been overlooked?

    To find out, Marina Sirota and her team at University of California San Francisco (UCSF) ran a machine-learning program on a database of anonymous electronic health records from patients. The AI algorithm was trained to pull out any common features shared by people who were ultimately diagnosed with Alzheimer’s over a period of seven years. The database includes clinical data, such as lab and imaging test results and diagnoses of medical conditions.

    “There were some things we saw that were expected, given the knowledge that we have about Alzheimer’s, but some of things we found were novel and interesting,” says Sirota. The results were published in Nature Aging.

    Heart disease, high cholesterol, and inflammatory conditions all emerged as Alzheimer’s risk factors—not surprising, since they’re known to contribute to the buildup of protein plaques in the brain. But the less expected conditions included osteoporosis in women and depression in both men and women. The researchers also saw unexpected patterns emerge closer to when people are diagnosed, such as having lower levels of vitamin D.

    Sirota and Alice Tang, a medical student in bioengineering who is the lead author of the paper, stress that these factors do not always mean that a person will develop Alzheimer’s. But they could be red flags that a patient can address to potentially lower their risk. “Picking up these factors gives us clues that a diagnosis of Alzheimer’s might be coming, and things like [high cholesterol] and osteoporosis are modifiable [with treatments],” says Tang.

    Whether or not treating these issues can actually lower a person’s risk of developing Alzheimer’s isn’t clear yet; the study wasn’t designed to answer that question. Sirota and her team plan to continue mining the database of health records to determine if people receiving treatments for conditions like osteoporosis or high cholesterol, for example, eventually had a lower risk of Alzheimer’s than patients who had those conditions but didn’t treat them. “We can retrospectively look at treatment data in the electronic medical records, so that’s definitely a direction forward to determine if we can leverage any existing therapies to lower risk,” says Sirota.

    Tang also hunted for genetic factors associated with things like high cholesterol or osteoporosis and Alzheimer’s that could further explain the connection between these risk factors. The link between cholesterol and Alzheimer’s turns out to be related to the ApoE gene; scientists have known that a specific form of the gene, ApoE4, is associated with a higher risk of developing Alzheimer’s. Tang also identified a gene associated with both osteoporosis and Alzheimer’s that could become a new research target for a possible treatment.

    The study shows the power of machine learning in helping scientists to better understand the factors driving diseases as complex as Alzheimer’s, as well as its ability to suggest potential new ways of treating them.

    More From TIME

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    Alice Park

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  • The Narcissistic Culture of “Image” and Excessive Self-Monitoring

    The Narcissistic Culture of “Image” and Excessive Self-Monitoring

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    In a world obsessed with public image and attention-seeking, learn about the cultural forces propelling society to become more narcissistic – and how this influences us to be in a constant state of self-scrutiny.



    The idea that our culture is becoming more narcissistic and self-centered is not new.

    Historian and social critic Christopher Lasch’s book The Culture of Narcissism was first published in 1979. By that time, the 1970s were already dubbed the “Me-generation.” Americans were increasingly shifting focus to concepts like “self-liberation,” “self-expression,” and “self-actualization,” while untethering themselves from past traditions and social responsibilities.

    Interestingly, Lasch traces the narcissistic roots in America back way further, starting with the early days of the Protestant work ethic and its singular focus on labor, money, and wealth-building, including the old “pull yourself up by your bootstraps” mantra.

    This early thread of American hyper-individualism continues into the New Age movement at the turn of the 20th century with its focus on personal happiness and spiritual fulfillment, as well as the popularity of Ayn Rand’s “virtue of selfishness,” and the rise of celebrity-worship and fame-seeking that still characterizes much of American life today whether it be in politics, sports, art, or entertainment.

    Things appear to be getting worse. The book was written over 40 years ago, but a lot of the observations in it seem strangely prophetic when looking at the world today. Lasch accurately describes how narcissistic trends have evolved on a societal and cultural level, and you can perfectly extend his theories to explain our modern culture.

    Before you continue reading, remember this is a cultural analysis of narcissistic tendencies and it isn’t focused on clinical or psychological definitions of Narcissistic Personality Disorder (NPD).

    Many people act more narcissistic because that’s what our society rewards and that’s how people think they need to act to get ahead in today’s world.

    One can even look at certain narcissistic tendencies as a survival strategy in an otherwise competitive, atomized, isolated – “every man for himself” – world.

    Now let’s dive into how our modern culture amplifies and rewards narcissism.

    The narcissist craves an audience

    First, the most defining characteristic of a narcissist is that they depend on the attention and validation of others to feel good about themselves.

    Contrary to the popular myth that the narcissist suffers from excessive self-love, the truth is they are deeply insecure and lack true confidence and self-esteem. The main reason they brag, show off, or puff-up-their-chests is only to appear strong when deep down they feel weak.

    As a result the narcissist is obsessed with their image and appearance. They feel they need to “win people over” to be accepted and liked by others, and this requires a carefully manufactured persona they create for the public.

    This deeply rooted “need for attention” plays a central theme in Lasch’s analysis:

      “Narcissism represents a psychological dimension of dependence. Notwithstanding his occasional illusions of omnipotence, the narcissist depends on others to validate his self-esteem. He cannot live without an admiring audience. His apparent freedom from family ties and institutional constraints does not free him to stand alone or to glory in his individuality. On the contrary, it contributes to his insecurity, which he can overcome only by seeing his ‘grandiose self’ reflected in the attention of others, or by attaching himself to those who radiate celebrity, power, and charisma.”

    Without an audience to appreciate them, the narcissist struggles to find their self-worth. They don’t believe in themselves – they need “proof” they are a good or important person through the eyes of others.

    To the narcissist, any attention is better than none at all; even negative attention like gossip, drama, and criticism feeds into their egos by letting them know they are still front and center.

    In a society that rewards attention for the sake of attention (including fame and notoriety), the narcissist grows and thrives. Who knows, that next scandal with a famous celebrity may be their big breakthrough – whatever gets them into the limelight!

    Image-centrism: The society of the spectacle

    One major contributor to the rise of narcissistic tendencies is that our culture is becoming more image-centric.

    Popular ideas on what true “happiness,” “success,” “fame,” “beauty,” and “achievement” look like are based on outward images and appearances increasingly fed into our culture through photographs, movies, television, and advertising:

      “[One] influence is the mechanical reproduction of culture, the proliferation of visual and audial images in the ‘society of the spectacle.’ We live in a swirl of images and echoes that arrest experience and play it back in slow motion. Cameras and recording machines not only transcribe experience but alter its quality, giving to much of modern life the character of an enormous echo chamber, a hall of mirrors. Life presents itself as a succession of images or electronic signals, of impressions recorded and reproduced by means of photography, motion pictures, television, and sophisticated recording devices.”

    This book was written before the internet and social media which have only increased our “image-centrism” tenfold. Selfies, avatars, memes, filters, photoshop, and AI have all continued to add more layers to this hyper-reality between manipulated images and how we choose to present ourselves.

    This constant barrage of cultural images shapes our beliefs and map of reality. It subconsciously puts ideas in our heads about what “happiness,” “success,” and “beauty” are supposed to look like.

    Once these social images are set in our minds, we naturally feel the desire to live up to them.

    Narcissists can often be the most sensitive to these social images because they fear their true self isn’t good enough, so they take society’s picture of “success” and try to mirror that image back to others.

    On the surface, the narcissist is a crowd-pleaser. They don’t trust their own judgement, so if society says this is what “happiness” or “success” looks like, then they will try to mimic it the best they can.

    Everyone has an audience now

    Technology, internet, social media, cameras, and recording devices have created a world where everyone feels like they have an audience all-the-time.

    Family photo albums and home videos were early stages in turning “private moments” into “public consumption,” but now we have people over-sharing every meal, date, and shopping spree on their social media feeds.

    Lasch correctly identifies this trend back in the 1960s-70s, including a mention of the popular show Candid Camera, which was one of the first “hidden camera” TV shows:

      “Modern life is so thoroughly mediated by electronic images that we cannot help responding to others as if their actions – and our own – were being recorded and simultaneously transmitted to an unseen audience or stored up for close scrutiny at some later time. ‘Smile you’re on candid camera!’ The intrusion into everyday life of this all-seeing eye no longer takes us by surprise or catches us with our defenses down. We need no reminder to smile, a smile is permanently graven on our features, and we already know from which of several angles it photographs to best advantage.”

    Life is recorded and shared now more than ever before. Today everyone has an audience and many people can’t help but see themselves as the “main character” of their own carefully edited movie.

    Unfortunately, we have this audience whether we like it or not. Every time we are out in public, someone may whip out their phones, capture an embarrassing moment, and upload it to the internet for millions to watch. You never know when you may go “viral” for the wrong reasons. The rise of online shaming, doxing, and harassment puts people in a perpetual state of high alert.

    That’s a stressful thought, but it perfectly represents this state of hyper-surveillance we are all in, where there’s always a potential audience and you feel constant pressure to showcase the “best version of yourself” in every waking moment, because you never know who is watching.

    Self-image and excessive self-monitoring

    In a world that rewards people solely based on the “image” they present, we naturally become more self-conscious of the image we are projecting to others.

    This leads to a state of endless self-monitoring and self-surveillance. We see ourselves through the eyes of others and try to fit their image of what we are supposed to be. No matter what we choose to do with our lives, the most pressing questions become, “How will this make me look?” or “What will people think of me?”

    While people naturally want to present themselves in the best way possible and form strong first impressions, an excessive degree of self-filtering and self-management can cause us to lose our sense of identity for the sake of superficial acceptance, internet fame, or corporate climbing.

    At worst, we increasingly depend on this these manufactured images to understand ourselves and reality:

      “The proliferation of recorded images undermines our sense of reality. As Susan Sontag observes in her study of photography, ‘Reality has come to seem more and more like what we are shown by cameras.’ We distrust our perceptions until the camera verifies them. Photographic images provide us with the proof of our existence, without which we would find it difficult even to reconstruct a personal history…

      Among the ‘many narcissistic uses’ that Sontag attributes to the camera, ‘’self-surveillance’ ranks among the most important, not only because it provides the technical means of ceaseless self-scrutiny but because it renders the sense of selfhood dependent on the consumption of images of the self, at the same time calling into question the reality of the external world.”

    If you didn’t share your meal on social media, did you really eat it? If you didn’t update your relationship status online, are you really dating someone?

    For many people, the internet world has become “more real” than the real world. People don’t go out and do adventurous things to live their lives, but to “create content” for their following.

    Who looks like their living their best life? Who is experiencing the most FOMO on the internet? In a narcissistic world, we start seeing our “digital self” in competition with everyone else – and the only thing that matters is that it looks like we are having a good time.

    More and more, we consume and understand ourselves through these technologies and images. We depend on photo galleries, reel clips, and social media posts to chronicle our life story and present the best version of ourselves to the world. If the internet didn’t exist, then neither would we.

    In the sci-fi movie The Final Cut people have their entire lives recorded through their eyes; then after they die, their happy memories are spliced together to give a “final edit” of the person’s life. Many of us are perpetually scrutinizing and editing this “final cut” of our own lives.

    The invention of new insecurities

    Everything is being observed, recorded, and measured, so we have more tools than ever to compare ourselves against others.

    This leads to the invention of all types of new insecurities. We are more aware of the ways we’re different from others, whether it’s our jobs, homes, relationships, health, appearances, or lifestyles. We can always find new ways we don’t “measure up” to the ideal.

    New technologies create new ways to compare. Before you know it, you have people in heated competitions over who can do the most steps on their Fitbit, or consume the least amount of calories in a week, or receives the most likes on their gym posts. The internet becomes a never-ending competition.

    Of course, measuring your progress can be a valuable tool for motivation and reaching goals. The problem is when we use these numbers to measure up against others vs. measure up against our past self. Always remember that everyone is on a completely different path.

    It’s well-known that social comparison is one of the ultimate traps when it comes to happiness and well-being. You’ll always be able to find someone who has it better than you in some area of life, and with the internet that’s usually an easy search.

    These endless comparisons touch on all aspects of life and heighten self-scrutiny and self-criticism. Finding and dwelling on even “minor differences” can spiral into a cycle of self-pity and self-hate. If we don’t remove ourselves from these comparisons, then we have no choice but to try to live up to them and beat ourselves up when we fail.

    Conclusion

    The goal of this article was to describe some of the key forces that are making society more narcissistic and self-centered.

    Different cultural beliefs and attitudes incentive certain personality traits over others. Our current world seems to continue moving down a more narcissistic path, especially with the increased focus on “image” (or “personal brand”) that we build for ourselves through the internet and social media.

    Most of the ideas in this article are based on the book The Culture of Narcissism which, despite being written over 40 years, is an insightful look into how these social forces continue to grow and evolve.

    Do you feel like our current society is getting more narcissistic? How have these social forces influenced the way you live?


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    Steven Handel

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  • ALS And Medical Marijuana

    ALS And Medical Marijuana

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    Star Trek actor Kenneth Mitchell lost his battle with ALS.  Can Medical Marijuana help others who suffer?

    The Fresh Toast – It is a devastating disease and more research needs to be done to help patients. And in regards to help, what about ALS and medical marijuana?

    Roughly over 5,000 people in Canada and the U.S. are diagnosed with ALS each year with over 20,000 smuggling with the disease.  Over 15 people are diagnosed daily. ALS is estimated to be responsible for as many as five in every 100,000 deaths in people 20 years or older.  The average life expectancy of a person with ALS is between two to five years from the time of diagnosis. Some people do live for more than five years. More than half of all ALS patients live more than three years after diagnosis, 20 percent live five years or more, up to 10 percent live more than 10 years, and about five percent live 20 years or more. What about ALS and medical marijuana.

    RELATED: Science Says Medical Marijuana Improves Quality Of Life

    Amyotrophic lateral sclerosis is a fatal type of motor neuron disease. It is characterized by progressive degeneration of nerve cells in the spinal cord and brain. It is also called Lou Gehrig’s disease, after a famous baseball player who died from the disease.

    Currently, there is no cure for ALS but there are some treatments available.

    Cannabis has properties applicable to symptom management of ALS, including analgesia, muscle relaxation, bronchodilation, saliva reduction, appetite stimulation, and sleep induction. With respect to the treatment of ALS, from both a disease modifying and symptom management viewpoint, clinical trials with cannabis are key to helping patients. Based on the currently available scientific data, it is reasonable to think that cannabis might significantly slow the progression of ALS, potentially extending life expectancy and substantially reducing the overall burden of the disease.

    RELATED: 5 Morning Activities To Help You Feel Happier

    As ALS progresses, though, more and more symptoms are noticed. These are the most common symptoms of ALS:

    • Twitching and cramping of muscles, especially those in the hands and feet
    • Loss of motor control in the hands and arms
    • Impairment in the use of the arms and legs
    • Tripping and falling
    • Dropping things
    • Persistent fatigue
    • Uncontrollable periods of laughing or crying
    • Slurred or thick speech and trouble in projecting the voice

    As the disease progresses, symptoms may include:

    • Trouble breathing
    • Trouble swallowing
    • Paralysis

    If you have any of these symptoms, it is important to seek a physician’s guidance immediately. Otherwise, be an advocate and champion for more medical research.

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    Amy Hansen

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  • Parkinson’s Disease and Medical Marijuana

    Parkinson’s Disease and Medical Marijuana

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    Michael J Fox brought attention to Parkinson’s at his recent appearance at the BAFTA awards.  But what about Parkinson’s Disease and Medical Marijuana

    Parkinson’s disease is one of the worst things to happen to a person. Ultimately, an active mind will be trapped in a non-functioning body. Along with the physical symptoms of Parkinson’s, many people with the diagnosis also experience psychosis, which begins with mild symptoms. This mental side of Parkinson’s can start with confusion and progress to include hallucinations and dementia. Michael J. Fox, the actor, is one of the most famous faces of the disease. The actor received a standing ovation during a surprise appearance at the British Academy Film Awards (BAFTA) Sunday. But what about Parkinson’s disease and medical marijuana.

    RELATED: Science Says Medical Marijuana Improves Quality Of Life

    Long an advocate for more research and discovering treatments to help patients, Fox has been a leader in the field.  His Foundation has shared research to date lacks the data to prove benefits or safety. Thus, doctors don’t have strong evidence to guide recommendations on what to use or how to truly help patients. Still, many people are interested in trying this therapy. In 2020, The Michael J. Fox Foundation convened a workshop on medical marijuana with field leaders and other Parkinson’s organizations.

    The limited amount of true research completed has had mixed or conflicting results (some positive, some negative). On questionnaires, people often report benefit on pain, sleep, mood, or motor symptoms such as tremor or stiffness. But many also report side effects. This leaves patients, doctors and researchers with insufficient evidence to guide use.

    Tetrahydrocannabinol (THC) is the principal psychoactive constituent of cannabis. In limited studies, THC has shown to improve both activity and hand-eye coordination in an animal model. A clinical study of 22 patients with the Parkenson’s and smoking marijuana, resulted in improvement of motor symptoms such as bradykinesia, resting tremor, rigidity, and posture, along with with non-motor symptoms such as sleep and pain.

    RELATED: 5 Morning Activities To Help You Feel Happier

    Cannabis has been used for hundreds of years for pain relief, improving sleep and for other purposes, there is still very little evidence regarding its efficacy and safety. Parkinson’s Europe is more positive toward research and information. They note many clinical studies into cannabis as a Parkinson’s treatment have been hampered by regulatory restrictions or have had various shortcomings.

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    Amy Hansen

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  • AI Writes Scientific Papers That Sound Great—But Aren’t Accurate

    AI Writes Scientific Papers That Sound Great—But Aren’t Accurate

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    First came the students, who wanted help with their homework and essays. Now, ChatGPT is luring scientists, who are under pressure to publish papers in reputable scientific journals.

    AI is already disrupting the archaic world of scientific publishing. When Melissa Kacena, vice chair of orthopaedic surgery at Indiana University School of Medicine, reviews articles submitted for publication in journals, she now knows to look out for ones that might have been written by the AI program. “I have a rule of thumb now that if I pull up 10 random references cited in the paper, and if more than one isn’t accurate, then I reject the paper,” she says.

    But despite the pitfalls, there is also promise. Writing review articles, for example, is a task well suited to AI: it involves sifting through the existing research on a subject, analyzing the results, reaching a conclusion about the state of the science on the topic, and providing some new insight. ChatGPT can do all of those things well.

    Kacena decided to see who is better at writing review articles: people or ChatGPT. For her study published in Current Osteoporosis Reports, she sorted nine students and the AI program into three groups and asked each group to write a review article on a different topic. For one group, she asked the students to write review articles on the topics; for another, she instructed ChatGPT to write articles on the same topics; and for the last group, she gave each of the students their own ChatGPT account and told them to work together with the AI program to write articles. That allowed her to compare articles written by people, by AI, and a combination of people and AI. She asked faculty member colleagues and the students to fact check each of the articles, and compared the three types of articles on measures like accuracy, ease of reading, and use of appropriate language.

    Read More: To Make a Real Difference in Health Care, AI Will Need to Learn Like We Do

    The results were eye-opening. The articles written by ChatGPT were easy to read and were even better written than the students’. But up to 70% of the cited references were inaccurate: they were either incoherently merged from several different studies or completely fictitious. The AI versions were also more likely to be plagiarized.

    “ChatGPT was pretty convincing with some of the phony statements it made, to be honest,” says Kacena. “It used the proper syntax and integrated them with proper statements in a paragraph, so sometimes there were no warning bells. It was only because the faculty members had a good understanding of the data, or because the students fact checked everything, that they were detected.”

    There were some advantages to the AI-generated articles. The algorithm was faster and more efficient in processing all the required data, and in general, ChatGPT used better grammar than the students. But it couldn’t always read the room: AI tended to use more flowery language that wasn’t always appropriate for scientific journals (unless the students had told ChatGPT to write it from the perspective of a graduate-level science student.)

    Read More: The 100 Most Influential People in AI

    That reflects a truth about the use of AI: it’s only as good as the information it receives. While ChatGPT isn’t quite ready to author scientific journal articles, with the proper programming and training, it could improve and become a useful tool for researchers. “Right now it’s not great by itself, but it can be made to work,” says Kacena. For example, if queried, the algorithm was good at recommending ways to summarize data in figures and graphical depictions. “The advice it gave on those were spot on, and exactly what I would have done,” she says.

    The more feedback the students provided on ChatGPT’s work, the better it learned—and that represents its greatest promise. In the study, some students found that when they worked together with ChatGPT to write the article, the program continued to improve and provide better results if they told it what things it was doing right, and what was less helpful. That means that addressing problems like questionable references and plagiarism could potentially be fixed. ChatGPT could be programmed, for example, to not merge references and to treat each scientific journal article as its own separate reference, and to limit copying consecutive words to avoid plagiarism.

    With more input and some fixes, Kacena believes that AI could help researchers smooth out the writing process and even gain scientific insights. “I think ChatGPT is here to stay, and figuring out how to make it better, and how to use it in an ethical and conscientious and scientifically sound manner, is going to be really important,” she says.

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    Alice Park

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  • U. Md. researchers examine how naptime impacts brain development in preschoolers – WTOP News

    U. Md. researchers examine how naptime impacts brain development in preschoolers – WTOP News

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    When should young children drop their afternoon nap? University of Maryland researchers are looking to better understand why the transition happens. 

    When should young children drop their afternoon nap? University of Maryland researchers are looking to better understand why the transition happens. 

    “We know sleep is very good for the brain, and it’s very good for our memories,” said University of Maryland professor Tracy Riggins. “Preschoolers are sponges that soak up a bunch of information about the world. They learn so much every day. Isn’t it interesting that that’s also the same time they’re transitioning out of the afternoon nap?”

    Riggins and her colleague Rebecca Spencer, from UMass Amherst, are conducting a first-of-its-kind study on preschoolers, sleep, memory and the brain.

    Riggins said children typically drop the nap between two and eight years of age. They want to understand why the transition happens, and why it might occur at different points in time for different kids.

    “We hope it’s a first step in understanding those intricate relations between memory, sleep, and the brain,” Riggins said. “We know they’re tied together, but we don’t actually know how they’re tied together.”

    She hopes the research provides more answers for educators, day care providers and parents. Riggins said there are currently no scientifically-based recommendations for napping in preschoolers, which is why daycares handle naptime differently.

    “Some of them have a mandatory two-hour rest period. Others have a 45-minute optional rest period, and some have no rest period at all,” she said. “And they might not remember anything from that class if they’re not able to take a nap, which will help them consolidate the information.”

    Riggins says they are looking to recruit about 180 children, ages 3-5, to participate in this study. Those children should be napping on average five days a week or more. Researchers would measure memory and brain activity while the kids are awake as well as when they’re sleeping. Participants will be compensated.

    If you’re interested in learning more about the study, visit the university’s Neurocognitive Development Lab website.

    Get breaking news and daily headlines delivered to your email inbox by signing up here.

    © 2024 WTOP. All Rights Reserved. This website is not intended for users located within the European Economic Area.

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    Linh Bui

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  • How to Write a Term Paper: 8 Expert Tips for Academic Success 2024 – Southwest Journal

    How to Write a Term Paper: 8 Expert Tips for Academic Success 2024 – Southwest Journal

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    The journey to writing an exceptional term paper is a marathon, not a sprint. It’s a process that tests your research, analytical, and writing skills, all rolled into one challenging assignment. 

    But fear not! With the right approach and guidance, crafting a term paper can become not just a means to score high grades but also an opportunity to deepen your understanding of your subject matter and enhance your academic skills.

    1. Truly Knowing What the Assignment Is Asking of You

    Truly Knowing What the Assignment Is Asking of You

    The first step in navigating the term paper sea is to thoroughly understand the assignment. It may seem straightforward, but many students falter by diving into the research and writing without a clear understanding of what is expected. Read the instructions carefully. 

    If anything is unclear, don’t hesitate to ask your professor for clarification or find here a site that may be able to help. Knowing the scope, topic, length, format, and deadline from the outset will set a strong foundation for your work.

    2. Choosing a Topic

    Selecting the right topic is crucial. It’s the seed from which your term paper will grow. Aim for a topic that is not only interesting to you but also appropriate for the scope of the assignment and your academic level. 

    It should be specific enough to be manageable but broad enough to allow for comprehensive research. 

    If you find yourself stuck at this stage, consult your professor or peers for suggestions. They can offer perspectives that might not have occurred to you.

    Criteria Description
    Interest Level Select a topic that personally interests you to stay motivated throughout the research and writing process.
    Appropriateness for Assignment Ensure the topic fits the guidelines and scope of the assignment provided by your instructor.
    Academic Level Suitability Choose a topic that matches your current academic standing and knowledge level, challenging yet manageable.
    Specificity The topic should be narrow enough to be thoroughly covered in the term paper but not so narrow that resources become scarce.
    Research Feasibility Consider the availability of resources, data, and literature to support your research on the topic.

    3. Conducting Thorough Research

    Conducting Thorough ResearchConducting Thorough Research

    Research is the backbone of your term paper. Begin by consulting a variety of sources, including books, academic journals, and reputable websites. Libraries, both physical and digital, are treasure troves of information. 

    Utilize databases such as JSTOR or Google Scholar to find relevant academic papers. As you research, keep meticulous records of your sources. This will make citing your references easier and ensure your paper is grounded in credible information.

    4. Crafting an Outline

    An outline is your roadmap, guiding you through the writing process. It helps organize your thoughts and structure your paper logically. Start with a broad overview, then break down the main sections into more detailed subsections. 

    This will help you identify areas that need more research or sections that are too complex and need simplification. An effective outline ensures that every part of your paper serves the overall argument or thesis statement.

    5. Writing the Draft

    Writing the DraftWriting the Draft

    With your outline in hand, it’s time to start writing. The introduction should hook the reader, present your thesis statement, and outline the structure of your paper. Each body paragraph should focus on a single idea or piece of evidence, supporting your thesis. 

    Use transitions to smoothly navigate from one idea to the next, maintaining a coherent flow throughout. The conclusion should tie everything together, reinforcing your thesis and highlighting the significance of your findings.

    The writing process is iterative. Don’t aim for perfection on the first draft. Focus on getting your ideas down on paper; refinement comes later.

    6. Revising and Editing

    The difference between a good term paper and a great one often lies in the revision stage. Start by reviewing your paper for content and structure. 

    Ensure each paragraph contributes to your thesis and that your argument flows logically. Then, move on to editing for clarity, coherence, and conciseness. Pay attention to grammar, punctuation, and style. 

    Tools like Grammarly or the Hemingway Editor can be invaluable but don’t rely on them completely. A manual review is irreplaceable.

    Finally, check your citations and references. They should adhere to the required format, whether it’s APA, MLA, or Chicago. This not only lends credibility to your paper but also avoids the pitfalls of plagiarism.

    7. Handling Feedback

    Seek Feedback from Your ProfessorSeek Feedback from Your Professor

    If possible, seek feedback from your professor or peers before the final submission. They can offer insights you might have missed and suggest improvements. Be open to criticism; it’s an opportunity for growth, not a personal attack. Use the feedback to refine your paper further.

    8. Final Touches and Submission

    Before submitting your paper, give it one last review. Check for any errors you might have missed and ensure that it meets all the assignment requirements. Submit your paper with confidence, knowing you’ve put in your best effort.

    FAQs

    How Can I Narrow Down a Broad Topic for My Term Paper?

    Narrowing down a broad topic requires a bit of brainstorming and preliminary research. Start by reading general sources about your topic to identify specific themes, trends, or issues that interest you. 

    Then, consider how these specific angles relate to the broader topic. It can also be helpful to discuss your ideas with your professor or classmates to gain different perspectives. Finally, formulate a research question or thesis statement that reflects the narrowed focus. This approach ensures your topic is manageable and tailored to the assignment’s scope.

    What Strategies Can I Use if I’m Struggling to Find Sources for My Topic?

    If you’re struggling to find sources, try altering your search terms or using synonyms to expand your search. Consult with a librarian, who can offer expert guidance on searching databases and may suggest resources you hadn’t considered. 

    How Do I Balance My Own Ideas with Research Findings in My Term Paper?

    How Do I Balance My Own Ideas with Research Findings in My Term Paper?How Do I Balance My Own Ideas with Research Findings in My Term Paper?

    To balance your own ideas with research findings, start by clearly stating your thesis or main argument. Use research findings to support your ideas, citing evidence that backs up your points. However, don’t just present the research; analyze it. 

    Discuss how the evidence supports your thesis, what it means in the context of your argument, and any limitations or counterarguments. Your own analysis and synthesis of the research are what will make your term paper unique and insightful.

    Can I Include Visuals in My Term Paper, and How Should I Do So?

    Yes, visuals such as graphs, charts, and images can be included in your term paper to support your arguments or illustrate complex ideas. Ensure that each visual is clearly labeled (e.g., Figure 1, Table 1) and accompanied by a caption explaining what it shows.

    Refer to the visuals in your text to guide the reader’s attention to them at relevant points in your argument. Always cite the source of the visual in accordance with the citation style you are using.

    How Do I Handle Contradictory Evidence in My Term Paper?

    Handling contradictory evidence is a crucial part of demonstrating critical thinking. Present the contradictory evidence fairly and objectively, then provide an analysis that explains why it does not undermine your thesis. 

    You can argue that the evidence is flawed, outdated, or limited in scope. Alternatively, you can acknowledge the complexity of the issue and refine your thesis to accommodate the nuanced view that emerges from considering all evidence. This approach shows that you have engaged deeply with the material and strengthens your argument.

    How Long Should I Spend on Each Stage of Writing My Term Paper?

    How Long Should I Spend on Each Stage of Writing My Term Paper?How Long Should I Spend on Each Stage of Writing My Term Paper?

    The time spent on each stage of writing a term paper can vary based on the length of the paper, the complexity of the topic, and your own working style. A balanced approach might involve spending 20% of your time on choosing a topic and conducting initial research, 30% on in-depth research and organizing your findings, 25% on writing the first draft, and 25% on revising, editing, and finalizing the paper.

    Adjust these percentages based on your specific needs and deadlines. Remember, starting early and allocating time for each stage can help reduce stress and improve the quality of your work.

    Final Words

    Writing a term paper is a substantial academic endeavor, but it’s also a deeply rewarding one. It challenges you to think critically, research deeply, and express your thoughts clearly and coherently. By following these steps, you equip yourself with a structured approach to tackle this challenge head-on. 

    Remember, academic writing is a skill honed over time. Each term paper is an opportunity to improve, learn, and grow as a scholar. Embrace the process, and you’ll find yourself not just surviving but thriving in the academic world.

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    Natalie Cowles

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  • RPI scientists to research Alzheimer’s treatment

    RPI scientists to research Alzheimer’s treatment

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    TROY, N.Y. (NEWS10) — Rensselaer Polytechnic Institute researchers will start working on a new approach to treating and preventing genetic diseases like Alzheimer’s. They received a grant from the National Institutes of Health to fund this research.

    “A delivery mechanism that works within the body itself could be a game changer,” said William Lawler, a doctoral student at RPI, who is working on the project.

    These researchers will search for ways to get around the immune system’s ability to destroy the gene therapy if it sees the new technology as a threat. They will also attempt to use systems in the human body to their advantage, like our own intercellular mail delivery system, to try and treat these genetic diseases.

    “Currently, gene editing tools, such as CRISPR, can only treat cells that have been removed from the body and processed in the lab. That limits the kinds of cells and conditions that can be treated,” Lawler said. “Our goal is to develop a technology that, once in the body, will correct the genetic mutations in brain cells linked to Alzheimer’s disease.”

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    Abbi Stanley

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  • Football Can Damage the Brains of High-School Players

    Football Can Damage the Brains of High-School Players

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    As much as fans will have to spend to attend the Feb. 11 Super Bowl, the game of football costs some professional players a vastly higher price, particularly when it comes to brain health. Researchers have found high rates of chronic traumatic encephalopathy (CTE)—a degenerative brain disease characterized by memory loss, confusion, mood swings, violence, suicidality and more—in autopsy studies of professional football players. CTE is caused by the head trauma and whole-body hits that are characteristic of the sport, which can lead to the dangerous buildup of certain proteins around blood vessels in the brain.

    Now it appears that the risk of brain trauma may also affect much younger athletes. According to a new study in JAMA Network Open, high-school football players can show alterations in brain tissue too. While it’s impossible to determine the presence of CTE without conducting an autopsy of the brain, the work provided disturbing evidence that playing the game early in life may lead to serious problems later on.

    “It’s a risk,” says Keisuke Kawata, an associate professor of clinical neuroscience at the Indiana University School of Public Health, and a coauthor of the new paper. “There are some brain changes that are normal over time. But among adolescent football players, we saw changes that it usually takes until middle age to exhibit.”

    To conduct their work, Kawata and his colleagues recruited 275 athletes from five Midwest high schools, 200 of whom were football players and 75 of whom participated in noncontact sports—specifically swimming, cross country, and tennis. All of the volunteers were males ages 13 to 18. Magnetic resonance imaging (MRI) scans were taken of their brains from May 2021 to July 2022, spanning two sports seasons.

    Read More: Scientists Are Just Beginning to Understand COVID-19’s Effect On the Brain

    The researchers discovered disturbing changes across multiple regions of the brain. One of the most significant was in the so-called sulcal regions, or the bottoms of the multiple folds that give the brain its characteristic cauliflower-like look. In a number of areas—including the cingulate cortex, which helps govern decision-making; the precentral gyrus, which controls volitional muscle movements; and the frontotemporal regions, which are broadly associated with personality, behavior, and language—the investigators saw a pronounced increase in sulcal depth. It is in the sulcal pits that spinal fluid can pool, and, when set in violent motion, can damage adjacent tissue.

    “It’s called the water-hammer effect,” says Kawata. “The torque and force are more pronounced there, and we start to see possible degeneration.”

    Pits were deeper in the football players than they were in kids who play noncontact sports, but the peaks of tissue around the sucal region, known as the gyri, were higher—again in the cingulate cortex, as well as in the frontoparietal region, associated with goal- or task-directed behavior; the precuneus, which, among other things, is involved in memory and mental imagery; and the lingual gyrus, which has a hand in memory and processing vision. The mechanism behind the growth of the gyri is not as clear as it is with the water-hammer effect, but there are clues. The researchers cite a 2016 study, which looked at mild cases of traumatic injury and suggested that elevated gyri might be a compensatory mechanism the brain switches on to support other impaired regions.

    Elsewhere in the football players’ brains, the MRIs detected atrophy of tissue. The outer surface of the brain, covering both cerebral hemispheres and representing about half of the organ’s overall mass, is the cerebral cortex, which takes part in a range of functions including learning, reasoning, memory, decision-making, intelligence, personality, and emotion. The researchers found thinning across much of the cortex—a discovery that particularly worries Kawata.

    Read More: A Blood Test for Alzheimer’s Disease Is Almost Here

    Ordinarily, he says, “it takes years and years to show this kind of macro level structural change. Some studies show 30 or 40 years before we see such cortical shrink.”

    The paper reaches no conclusions on what impact the cortical thinning has on the players’ cognitive processes; the cerebral cortex has so many jobs, distributed across so much brain area, that it will take further research to survey that landscape. But cognition and information processing are not the only functions in play. As with CTE and dementia, any changes to the morphology of the brain can have a hand in the development of psychiatric disorders. The researchers point to a 2019 paper which showed that increased cortical thickness and the growth of gyri in the cingulate cortex appear to be associated with major depressive disorder.

    “This is quite relevant,” says Kawata. “[Professional] football players with degenerative brain disorders almost always have psychiatric comorbidities. They become combative, irritable, violent. The student athletes are very well-behaved, respectful, nice football players. But there is a neurological sign that they may be at risk for psychiatric conditions.”

    For now, the investigators are not calling for a ban on full-contact football for youth, and Kawata, for one, sees virtues to the game. “It would be very detrimental to some kids to just go home in the middle  of the season,” he says. “They’d be on the couch, eating chips and watching TV all day long. I think that’s much worse than being on the field and learning.” But as the pros and scientists know, time on the field may exact a steep toll. 

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    Jeffrey Kluger

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  • Five new alien-faced species of millipede revealed in “remarkable” find

    Five new alien-faced species of millipede revealed in “remarkable” find

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    Five new spooky-looking species of millipede have been discovered, one of which belongs to a totally unknown group of critters.

    The new species, which resemble something out of a sci-fi movie, were found in the forest litter of Tanzania’s remote Udzungwa Mountains, according to a new paper in the European Journal of Taxonomy.

    “We record millipedes of all sizes during our fieldwork to measure forest recovery because they are great indicators of forest health, but we didn’t realize the significance of these species until the myriapodologists had assessed our specimens,” Andy Marshall, a professor of tropical forest conservation at the University of the Sunshine Coast, and discoverer of the new species, said in a statement.

    “It’s remarkable that so many of these new species did not appear in earlier collecting of millipedes from the same area, but we were still hoping for something new.”

    The heads of two of the new millipede species, Lophostreptus magombera and Udzungwastreptus marianae. These new species, alongside three others, were discovered in a forest in Tanzania.

    Credit: European Journal of Taxonomy 2024. DOI: 10.5852/ejt.2024.918.2405

    Millipedes are actually not insects, but something called diplopods, and are defined by their elongated bodies and plentiful legs. Despite the name millipede translating roughly to “thousand feet,” no species was known to have over 1,000 legs until 2020, when a species named Eumillipes persephone was found to have up to 1,300 legs.

    There are around 12,000 species of millipede worldwide, but the true total may be much higher. Some estimates predict that there may be 15,000 species in total, but others think that there may be as many as 80,000.

    Most millipedes are fairly small, but the largest species of millipede, found in Africa, can grow as large as 13.8 inches long. These new species were much smaller than this, at only around an inch long, and had 200 or so legs each.

    The five new species were named Lophostreptus magombera; Attemsostreptus cataractae; Attemsostreptus leptoptilos; Attemsostreptus julostriatus and Udzungwastreptus marianae, the latter of which was part of a whole new genus: Udzungwastreptus.

    This discovery was made during an expedition meant to examine how forests in the area were being affected by logging and other disturbances, and how woody vines may be taking over the region, driven by warmer temperatures.

    “The millipedes will help us to determine two very different theories on the role of vines on forest recovery—whether the vines are like bandages protecting a wound or ‘parasitoids’ choking the forest,” Marshall said.

    millipedes
    Box of sample millipedes collected by UniSC FoRCE project researchers in Tanzania. Some of these species have never before been seen.

    A.R. Marshall

    The new millipede specimens have been taken to Denmark’s Natural History Museum at the University of Copenhagen. This is not the first time that Marshall has discovered a new species, having already been responsible for uncovering a new species of chameleon, and a new species of tree.

    These discoveries, including the millipedes, are hoped to highlight the sheer amount of undiscovered diversity lurking in forests around the world.

    He said unearthing the new genus and species of millipedes highlighted the huge amount of discovery remaining in tropical forests.

    Do you have a tip on a science story that Newsweek should be covering? Do you have a question about millipedes? Let us know via science@newsweek.com.