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Tag: organ transplant

  • A head-on car crash sidelined a young mom. A rare transplant was the only option to get her life back.

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    For Lacy Cornelius Boyd, March 19, 2024, was an exciting day. She and her husband had taken their 6-year-old daughter to the Grand Canyon as part of a family road trip. Boyd, her husband and their daughter were planning to stop at McDonald’s before heading home to Oklahoma. 

    Everything was well — until their car hit a patch of black ice. 

    “We were spinning. My husband obviously lost control, and he hit another car head-on,” Boyd recalled. Everything else was a blur. 

    Boyd’s daughter had a broken arm. Her husband and the other driver were fine. Boyd had broken bones in her neck and ribs, a collapsed lung, and severe injuries to her intestines. She had six surgeries in five days.

    But the damage to her intestines — caused by a too-tight seatbelt — kept getting worse, Boyd said. 

    “They were trying to save my intestines, and every time they would go back in, they were just dying from no blood flow,” Boyd said. “I was told that most people have 35 feet of small intestine. I was left with about 35 inches.” 

    Lacy Cornelius Boyd, her husband and their daughter at the Grand Canyon.

    Lacy Cornelius Boyd


    “Just going through the motions”

    Boyd was discharged from the hospital after a month. She was diagnosed with short bowel syndrome and had an ileostomy bag attached to her side to collect waste. Her remaining intestines couldn’t process the nutrients from food, so she needed 12 hours of IV nutrition a day. She said her daughter was afraid of the tubes, wires and medical machines that now filled their home. Boyd was always weak and dehydrated, and never wanted to leave the house. 

    “If I went out to eat somewhere, I’d be in the bathroom immediately, or I’d have to go to the bathroom five times at a restaurant, so it was just embarrassing,” Boyd said. “I felt like everyone was enjoying their life and I was just going through the motions.” 

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    Lacy Cornelius Boyd in the hospital.

    Lacy Cornelius Boyd


    Boyd, who had previously worked in healthcare, regularly met with doctors to see if her quality of life could be improved. No one had answers. Finally, she followed up on an unlikely lead. During her hospitalization, a surgeon had told Boyd’s sister she should contact the Cleveland Clinic. 

    Boyd self-referred herself to the hospital system in November 2024. She met with general surgeon Dr. Masato Fujiki and after an evaluation, he suggested something she’d never heard of before: An intestinal transplant. 

    “I started crying. I think he thought I was sad, but I was really happy,” Boyd said. “Everyone had told me that was going to be my life.” 

    A rare, risky transplant 

    Intestinal transplants are a rare procedure, said Dr. Adam Griesemer, a transplant surgeon at NYU Langone. Only about 100 are done in the U.S. every year, compared to the 25,000 kidney transplants done annually, said Fujiki, the director of Cleveland Clinic’s Intestinal Transplant Program. 

    Intestinal transplants have the worst outcomes of any type of transplant, Griesemer said, so there is a “high threshold” for doctors to consider them. They are generally only recommended for children born with intestinal defects and people who will be dependent on IV nutrition for the rest of their lives, like Boyd, he said. 

    Intestinal transplant patients “really struggle with rejection and infections,” Griesemer said. Intestines harbor bacteria inside them, so during cases of organ rejection, the barrier preventing the bacteria from entering the bloodstream breaks down. Fujiki said rejection rates have been improving over the past decade, estimating that it has decreased from 40% of cases to about 8%. Medication can help reduce infections, he said. 

    Only about 50% of patients survive more than five years after receiving the transplant, Griesemer said. In comparison, kidney transplants have a 98% five-year survival rate. 

    “Prepared for the worst”  

    Boyd began the process of getting listed for an intestinal transplant in November. In July 2025, 16 months after the car crash, Boyd received the transplant at the Cleveland Clinic. The day of the operation was filled with emotion, she said. 

    “I was excited. I was nervous. I was sad about leaving my daughter, and I felt for the donor’s family,” Boyd said. “But really, I was prepared for the worst.” 

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    Lacy Cornelius-Boyd (center) with transplant coordinator Erika Johnson (left) and Dr. Masato Fujiki (right).

    Lacy Cornelius Boyd


    The operation took about 12 hours, Fujiki said. Everything went smoothly. But it was just the first step in a long process: Boyd spent the next three weeks recovering in the hospital, followed by three months of outpatient recovery in Cleveland so she could stay near her care team for close monitoring. 

    Boyd had no complications in her recovery, Fujiki said. Her ostomy bag was removed. She no longer needed IV nutrition. The weekend before Thanksgiving, she returned to Oklahoma.

    “It was amazing to be able to come home,” Boyd said. 

    A festive return home 

    Boyd arrived home just in time for beloved holiday traditions. After missing other milestones, like her daughter’s first day of school and Halloween, Boyd was relieved to be a part of the celebrations. 

    “My daughter is six now, but my husband carries her to the Christmas tree every morning to get her presents. I don’t know how much longer she’s going to let him do that,” Boyd said. “I was like, ‘This year might be the last time, and I’ll miss it.’ But I didn’t.” 

    Boyd remains on a regimen of anti-rejection medications and will continue to receive follow-up care at the Cleveland Clinic. Otherwise, normalcy reigns, and it feels like the last of the trauma from the crash has been repaired, she said.

    “It’s nice to take my daughter to school, pick her up, not have to worry about anything, to take her and to be able to go out to eat. I couldn’t drink Coke before. I couldn’t do normal things for like, a year and a half,” Boyd said. “It’s so much. Everyone is just a little bit more at peace.” 

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    Lacy Cornelius Boyd and her daughter in matching pajamas on Christmas Eve. 

    Lacy Cornelius Boyd


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  • Northwell is launching first adult pancreas transplant program | Long Island Business News

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    THE BLUEPRINT:

    • Northwell approved to start ‘s first adult pancreas .

    • Program adds to Northwell Transplant Institute’s existing kidney, heart, liver and lung services.

    • Launch addresses the needs of 800+ patients and 2,500 kidney-pancreas patients.

    • Expands options, potentially reducing or eliminating the need for insulin.

    The New York State Department of Health has given the green light to to   launch Long Island’s first adult pancreas transplant program.

    The Northwell Transplant Institute at (NSUH) were recently visited by DOH officials for a site visit – the final hurdle before the program becomes accessible to patients in New York and southern Connecticut.

    The institute is now one of 59 centers across the country that provides heart, kidney, liver, lung and pancreas programs under one roof, according to the U.S. Department of Health & Human Services. It also provides care for children in need of a new heart or kidney.

    “Northwell now consistently performs more than 200 kidney transplants a year with excellent outcomes,” Dr.  Nabil Dagher, senior vice president and director of Northwell Transplant Institute, said in a news release about the pancreas transplant program.

    “The goal has always been to bring pancreas transplantation to Long Island and marry these similar disciplines,” Dagher said. “We’ve attracted some of the best nephrologists and surgeons in the world, true experts in kidney disease and diabetes. Adding pancreas transplantation to the Northwell Transplant Institute’s already robust programs will further strengthen the care we deliver to all patients.”

    The program is launching at a time when 120,000 Americans need an organ transplant, including more than 800 awaiting a pancreas transplant and another roughly 2,500 seeking a combination kidney/pancreas transplant, according to the United Network for Organ Sharing.

    NSUH began performing adult kidney transplants in 2007 and launched a pediatric kidney transplant program at Cohen Children’s Medical Center in New Hyde Park in 2017. Dr. Niraj Desai joined Northwell in 2024 to oversee kidney transplantation and lead the launch of the pancreas program. Desai previously served as director of the kidney and pancreas transplant programs at Johns Hopkins School of Medicine in Baltimore.

    “The mission is to bring greater access to people in need, whether that’s through making more organs available for transplantation – which we’ve been working toward – or creating new pathways to receive a life-saving transplant,” Desai said in the news release. “We’ve pushed to expand the age and criteria for . I’m excited that we can open pancreas transplant to a new, underserved population.”

    The pancreas transplant program expands treatment options for patients with advanced diabetes. Often performed in conjunction with a kidney transplant, the procedure can restore the body’s natural ability to regulate blood sugar and reduce or eliminate the need for insulin.

    “Kidney transplantation has risen in recent years, driven by greater awareness of its benefits and an increased availability of donated organs,” Dr. Vinay Nair, medical director of Northwell’s Center for Kidney and Pancreas Transplantation, said in the news release.

    “Unlike kidney transplantation, pancreas transplantation has remained stagnant, largely due to a lack of public knowledge and an insufficient number of centers offering the procedure,” Nair added. “Our new program seeks to mitigate these challenges by both enhancing awareness and establishing local availability for pancreas transplantation.”


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    Adina Genn

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  • RFK Jr. moves to decertify organ transplant group

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    Watch CBS News



    Health and Human Services Secretary Robert F. Kennedy Jr. announced new action to reform the nation’s organ transplant system, as well as a move to decertify an organ procurement organization. Omar Villafranca has details.

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  • RFK Jr. announces move to decertify organ procurement organization amid efforts to reform organ donation

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    Washington — Health and Human Services Secretary Robert F. Kennedy Jr. announced on Thursday new action to reform the nation’s organ transplant system, as well as a a move to decertify an organ procurement organization.

    “Every American should feel safe becoming an organ donor and giving the gift of life, yet decades of ignored patient safety concerns have driven more and more Americans off the donor list,” Kennedy said. “Today, under President Trump’s leadership, we are taking bold action and historic action to restore trust in the organ procurement process.”

    Transplant experts said last year there had been a spike in people revoking organ donor registrations, after a report that a Kentucky man who’d been declared dead woke up just as a team was preparing to remove his organs. Since then, there have been more reports of attempts to remove organs from patients who had mistakenly been declared dead. 

    Kennedy said at a news conference that “we are acting because of years of documented patient safety data failures and repeated violations of federal requirements, and we intend this decision to serve as a clear warning.”

    The secretary said the Life Alliance Organ Recovery Agency, a division of the University of Miami Health System, “has a long record of deficiencies directly tied to patient harm.”

    “Unlike the Biden administration, which ignored these problems and failed to act, the Trump administration is setting a new standard that patient safety comes first,” Kennedy said. 

    Kennedy said along with the decertification, HHS is reforming the Organ Procurement and Transplantation Network and “investing in new ways to encourage organ donation.”

    Health and Human Services Secretary Robert F. Kennedy Jr. speaks during a press conference on the steps of the United States Department of Agriculture on July 14, 2025 in Washington, D.C.

    Michael M. Santiago / Getty Images


    In July, HHS announced a plan to begin reforming the organ transplant system, citing a federal investigation that “revealed disturbing practices by a major organ procurement organization.”

    Kennedy said in a statement at the time that the investigation, conducted by the Health Resources and Services Administration under HHS, showed “that hospitals allowed the organ procurement process to begin when patients showed signs of life,” calling it “horrifying” and pledging to hold accountable organ procurement organizations that coordinate access to transplants. 

    HHS said the investigation examined 351 cases where organ donation was “authorized, but ultimately not completed,” finding that nearly 30% showed “concerning features,” like neurological signs in patients that the agency said are incompatible with organ donation. And at least 28 patients “may not have been deceased at the time organ procurement was initiated.”

    More than 100,000 people are on the national transplant waiting list, and 13 people die each day waiting for a transplant, according to the Health Resources and Services Administration. 

    Kennedy has been pushing major changes to the nation’s health care systems since he was sworn in earlier this year. And he has faced criticism in recent weeks over his leadership of the department amid a number of departures from the Centers for Disease Control and Prevention. On Wednesday, Susan Monarez, who was ousted as CDC director by Kennedy less than a month after she was confirmed, testified before a Senate committee that she faced pressure from the secretary to change the childhood vaccine schedule, regardless of whether there was scientific evidence to support doing so.

    Kennedy testified before a different Senate committee earlier this month, where he defended the CDC shake-up, saying changes at the health agency were “absolutely necessary.” The secretary denied pressuring the former director to preapprove upcoming vaccine recommendations, and accused her of lying about why she was fired.

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  • Organ donor recipients gather to honor woman who save their lives

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    It’s an Eagan, Minnesota woman’s continued legacy. After Adelyn Miller died in 2023, her organs saved five lives, and four of those she saved gathered together to live out her legacy.

    “Oh man, I just miss talking to her,” said Vicki Wichmann Miller, Adelyn’s mother. 

    Adelyn Miller’s family says she was adventurous, loving and made people laugh. She was 20-years-old when ejected from a vehicle, fracturing her skull, killing her days later due to a brain herniation. 

    Her mother says she wanted to be a paramedic one day.

    “She was very much about helping everybody else,” said Miller. 

    Which is exactly what she did.

    “I owe her my life,” said Golownia, who received lungs.   

    Dennis Golownia


    “You saved my life and I’m eternally grateful,” said Kevin Enders, who received a liver. 

    “I just want her to know she’s changed my life,” said Jack Feast. Feast got Adelyn Miller’s heart. 

    Hopefully she could see it in my eyes, how grateful,” said Suzie Dauer, who got her kidney.

    “Being able to meet her recipients has been extremely healing to me,” Miller added.

    After Adelyn Miller’s passing, her mother reached out to her donors and heard back from four of the five. 

    On Saturday, they gathered together as one big Brady Bunch. Recipients and loved ones painted rocks that’ll be placed across the world. If you find one, you’ll notice a QR code linking to Adelyn’s story and her impact as a donor.

    organ-donation-meet-up.jpg

    WCCO


    “I feel like I’ve gained a whole new family with Vicki and everyone else that’s here in Minnesota,” said Feast.

    Feast, who lives in Illinois, can enjoy life with his daughter again. He has also gained new friends — or as he says ‘family’ members like Kevin, who also traveled from the Land of Lincoln for the weekend.

    “The fact we’re both still alive because of Adelyn is indescribable,” said Enders.

    Something that Dennis from the Milwaukee metro would also agree with.

    “I can see the scars on my chest and I still think of her,” he added while his granddaughter was hugging him.

    All signs that Adelyn’s legacy is alive.

    “She really impacted a lot of people” said MIller.

    To become an organ donor, register online through the National Donate Life Registry.

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    Frankie McLister

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  • New public dashboard aims to track the fairness of the allocation of organ donations – WTOP News

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    In an effort to make sure organ transplant matches are fair, the Department of Health and Human Services has launched a new public online tracking tool.

    In an effort to make sure organ transplant matches are fair, the Department of Health and Human Services has launched a new public online tracking tool.

    “Since the beginning of transplantation, there has always been a shortage of organs, not enough to go around for all the people who could benefit,” said Dr. Thomas Fishbein, executive director of the MedStar Georgetown Transplant Institute.

    He said the newly launched dashboard from the HHS is an effort to track whether organs are being fairly assigned.

    “There’s always a balance between, in a sense, the equity or the fairness of how the organ gets offered to someone, and … the speed and how efficiently the organ can be accepted by somebody, so that it doesn’t go to waste because it took too long,” Fishbein said.

    He said the tool was implemented because the HHS said they were finding organs were being given to patients out of the normal order.

    The aim is to crack down on “Allocation Out Of Sequence” events, or AOOS. This often happens when an organ isn’t a fit for patients at the top of the list and it goes out of sequence to whomever can accept it.

    “They might have gotten offered to 500 or 1,000 patients, nobody had accepted that organ, and so they would go out of sequence and say, ‘whoever will accept it can have the organ.’ Now, there will be a renewed focus on making sure that it is done in some orderly sequence,” Fishbein said.

    At MedStar Georgetown, he said, they have updated their organ transplant operations to presort through their list of patients waiting for transplants.

    “And annotate, essentially, the list so that we know which patients have been disadvantaged by the allocation system and for whom we need to keep a special eye out for special offers of organs that might not have been accepted by people higher up on the list,” Fishbein said.

    He said that while this change will track how the programs are finding patients for available organs, he’s proud of how MedStar Georgetown and other programs are continuing to ethically allocate organs for transplants.

    “We have a very robust, very mature program and system, and in the vast majority of programs across the country, people are working hard and ethically to benefit patients like those on our list,” he said. “Overall, the organ transplant system is good, ethical and these changes that are occurring are relatively minor tweaks in the system.”

    WTOP’s Grace Newton contributed to this story.

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    © 2025 WTOP. All Rights Reserved. This website is not intended for users located within the European Economic Area.

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    Valerie Bonk

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  • Twin Cities teen discharged from Mayo Clinic with new heart after 246-day-long stay

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    A Blaine, Minnesota, boy is home after 246 days in the hospital with a new heart thanks to a donor.

    “Getting a heart is not an easy journey, I’d say. And it’s not a quick journey,” Konner Repp said.

    In January, WCCO told you about Konner and his brother, who were both born with heart defects. The Spring Lake Park High School junior was born with hypoplastic right heart, a rare syndrome where part of the heart doesn’t form completely. It led to three open-heart and over seven heart catheterization surgeries.

    “I don’t even know where to start,” said Jennifer Repp, his mother.

    After a recent decline, the 16-year-old went into the hospital on Jan. 6, 202,5 ultimately needing a new one. But with months and weeks of waiting for a match, June 24 brought a ray of hope.

    After 246 days in the hospital, 16-year-old Konner Repp was allowed to go home.

    Jennifer Repp


    “We are blessed beyond belief that Konner has a beautiful new heart beating thanks to a beautiful donor,” said Jennifer Repp.

    Konner Repp was discharged from Mayo Clinic in Rochester, coming home to the sights and sounds of a community that supported him all along.

    “They were all fighting with me during the whole thing,” Konner Repp said.

    Soon, he will get back to being the high schooler he is, after a good night’s sleep, of course.

    An online fundraiser for Konner Repp has raised over $26,000. His mom says it’s still a long road ahead. 

    No information on the heart donor has been provided.

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    Frankie McLister

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  • Putin and China’s Xi heard on hot mic discussing life-prolonging organ transplants and immortality

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    China’s President Xi Jinping and his visiting Russian counterpart Vladimir Putin discussed life-prolonging organ transplants and immortality as they chatted before a massive military parade in Beijing on Wednesday, in comments picked up by state media microphones.

    Historic images showed Xi shaking hands and speaking with Putin and North Korean leader Kim Jong Un as they walked down a red carpet by Tiananmen Square, in scenes viewed as a challenge to President Trump and the U.S.-led global order that has prevailed for more than a century.

    “These days… 70 years old,” Xi mused in Mandarin as he walked beside Putin and Kim, according to video aired by Chinese state broadcaster CCTV. Xi’s translator conveyed the remarks to Putin, who is then heard in Russian quoting a line from a Tang dynasty poem: “In the past, it used to be rare for someone to be older than 70 and these days they say that at 70 one’s still a child.” 

    Elderly residents gather at a local civil affairs service center to watch the live broadcast of China’s Victory Day military parade from Beijing, Sept. 3, 2025, in Chongqing, China.

    Cheng Xin/Getty


    Putin then turned toward Xi, speaking while gesturing with his hands, though his words are inaudible on the CCTV feed. The same Chinese translator then relays Putin’s remarks to Xi.

    “With the… development of biotechnology, human organs can be continuously transplanted, people could get younger as they grow older, and may even become immortal,” Putin said, according to the translator. 

    Xi then spoke again in Mandarin as the camera cut away: “Predictions are, in this century, it may be… possible to live to 150 years old.”

    Putin confirmed the exchange during a news conference later Wednesday.

    “Ah, I think it was when we were going to the parade that the chairman spoke about this,” he told reporters, referring to Xi.

    “Modern means — both health improvement and medical means, and then even all kinds of surgical ones related to organ replacement — allow humanity to hope that active life will continue not as it does today,” Putin added.

    China and Russia’s “no limits partnership”

    Xi and Putin, along with Kim and Iran’s Supreme Leader Ayatollah Ali Khamenei, have been dubbed an “Axis of Upheaval” by some Western analysts, and Xi’s decision to bring together the leaders of some of the most heavily sanctioned nations in the world this week was clearly calculated. 

    The parade was the first time Kim had ever appeared together with both Xi and Putin — providing him a first multilateral diplomatic event.

    Xi and Putin have made their ambition to shake up the global status quo clear for several years.

    “We, together with you and with our sympathizers, will move towards a multipolar, just, democratic world order,” Russia’s longtime Foreign Minister Sergey Lavrov said in 2022, ahead of a meeting with his Chinese counterpart.

    TOPSHOT-RUSSIA-CHINA-DIPLOMACY

    Russian President Vladimir Putin and his Chinese counterpart Xi Jinping shake hands during a welcoming ceremony before their talks at the Kremlin in Moscow on May 8, 2025.

    EVGENIA NOVOZHENINA/POOL/AFP via Getty Images


    China and Russia have declared a “no limits partnership,” and neither Xi nor Putin, who are both 72, has ever expressed any intention of stepping down from their respective roles at the helm of their nations.

    While Xi’s predecessors Jiang Zemin and Hu Jintao relinquished power after 10 years in office, he abolished term limits in 2018 and, in 2023, was handed a third term as Chinese president.

    Putin was elected to a record fifth six-year term just last year in Russia. Critics dismissed the vote as a patently undemocratic farse, as virtually all of Putin’s serious political opponents were barred from running, and many of them were jailed. 

    Putin has twice used his leverage as Russia’s autocratic leader to amend the constitution so that he can theoretically stay in power until he’s in his mid-80s. He already is the longest-serving Kremlin leader since Soviet dictator Josef Stalin.

    China, meanwhile, has historically had one of the lowest rates of organ donation in the world, with a severe shortage of organ donors and a long-standing black-market organ trade. In 2016, about four years into Xi’s tenure as leader, surgeons from the World Health Organization gathered in Beijing to try to allay skepticism about whether Chinese hospitals had, as claimed, stopped performing transplants with the organs of executed prisoners.

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  • Her little sister needed a kidney. The donation let them both live their dreams

    Her little sister needed a kidney. The donation let them both live their dreams

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    As children, sisters Amaris and Dominique Elston were inseparable. Their parents remember the two of them sharing everything and always having each others’ backs, no matter the situation. 

    That bond didn’t change as they grew older, and when an 18-year-old Dominique was diagnosed with focal segmental
    glomerulosclerosis, a chronic kidney disease that soon led to kidney failure, Amaris was again ready to help her sister.

    “I told Amaris ‘Dominique is in kidney failure. Her kidney function was at 19%, and she’s going to need a kidney transplant eventually,'” Denise Elston, their mother, said. “Thirty seconds later, Amaris said, ‘Can I give her one?'” 

    Amaris (back) and Dominique (front) Elston as children. 

    The Elston family


    Amaris, then interviewing for medical schools, knew her family had a history of kidney disease, so she wasn’t sure she’d be able to donate. Dominique didn’t want her sister to put her life on hold but as her condition deteriorated and her kidney function dropped to just 5%, despite dialysis treatments, Amaris knew she had to do something. Without telling Dominique, she got tested and learned she was a match. 

    “She’s my little sister,” Amaris said. “As a big sister, it’s natural to want to jump in and save her from everything that life has to offer, even failing kidneys. I knew this was the best option that she had at getting back on track with life and doing all the things she wanted to do. It was never really a question.” 

    Avoiding years on a waiting list 

    About 140,000 people are on the waiting list for a kidney transplant in the United States, according to Dr. Kelly Birdwell, medical director of kidney transplantation at Vanderbilt University Medical Center, who was not involved in the Elston sisters’ care.

    The average American waits about five years for a kidney donation through the waiting list. Black Americans are also disproportionately represented on the waiting list, Birdwell said. Black people are more likely to have Type B blood, which has fewer compatible donors, she said, and there is also “an excess risk of kidney disease in the African American population.” 

    In 2019, more than 14,000 Black kidney transplant candidates were moved up on the national waitlist after it was found a widely-used test was overestimating how well Black people’s kidneys were functioning, making them seem healthier than they were and extending the amount of time they waited. 


    Thousands of Black kidney transplant candidates moved up on waitlist after testing bias found

    03:20

    Amaris said all of those factors were on her mind when she decided she wanted to donate to her sister. In 2023, 21,765 kidney transplants were completed, with 6,294 of those organs coming from living donors. About 60% of living donors are related to the recipient, Birdwell said. 

    To donate a kidney, interested family members do a round of initial testing that confirms the donor is compatible with the recipient. That’s followed by a longer evaluation, Birdwell explained, to make sure the donation won’t put the potential donor at risk. The evaluation includes bloodwork and imaging to confirm the potential donor is in good health. Once those stages are successfully completed, it’s just a matter of scheduling the surgery. 

    For the Elstons, that meant waiting until Amaris finished her first semester of medical school at the University of Alabama at Birmingham. In December 2018, the sisters were again side-by-side, waiting for their operations at the University of Vanderbilt’s Transplant Center. Amaris’ operation was first. Birdwell estimates that a donor surgery is about two hours, while a recipient’s surgery, scheduled for later in the day, is about three hours. 

    When Amaris and Dominique reunited after their operations, the eldest of the two could already see a change in her baby sister. 

    “I remember laying in the bed and being in a lot [of] pain, and Dominique walking down the hallways like ‘No big deal,’ and in that moment, it solidified that I knew I had made the right decision,” Amaris said. “She looked like a whole new person, in less than 24 hours. She was just bopping in my room, sitting in my chair. It was worth it.” 

    02.jpg
    Dominique (left) and Amaris (right) after transplant. 

    The Elston family


    Working together to save lives 

    Amaris gave her younger sister more than a kidney. She also gave Dominique the chance to follow her sister into the field of medicine. 

    Amaris graduated from UAB’s Heersink School of Medicine in 2022. Just two years later, Dominique graduated from the UAB School of Nursing with her bachelor’s degree in nursing. Amaris cheered her on from the audience. 

    “After going through what we went through, it was kind of like a calling for me to go into (nursing),” Dominique said. “It wasn’t really something I had to think about. I felt like it was something that was meant for me.” 

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    Dominique (left) and Amaris (right) at Dominique’s graduation ceremony from UAB. 

    The Elston family/UAB


    Now, both sisters are working in the neurology field. Amaris is a neurology resident at the Medical University of South Carolina, and Dominique is a neurology intensive care unit nurse at UAB. The two are the first members of their family to enter the medical field. Though the sisters are now separated by more than more than 400 miles, their bond is stronger than ever. 

    “It’s been fun having somebody that is with you through everything, because if you want to talk about the bad parts, the good parts, you can,” Amaris said. “It feels good to know that there’s somebody right beside you that can understand how you feel and what you’re going through. We’ve been each other’s best friends amid some of our darkest moments, so this is just another journey that we’re on together.”  

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  • Doctors perform first-ever combined heart pump and pig kidney transplant

    Doctors perform first-ever combined heart pump and pig kidney transplant

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    For the first time, surgeons at NYU Langone Health performed a combined mechanical heart pump and gene-edited pig kidney transplant, helping a 54-year-old woman with heart and kidney failure.

    Before the two procedures, which took place earlier this month, New Jersey native Lisa Pisano faced heart failure and end-stage kidney disease that required routine dialysis, and she was not a candidate for a human transplant.

    “I was pretty much done,” Pisano told CBS News chief medical correspondent Dr. Jon LaPook, who is also a professor at NYU Langone. “I couldn’t go up the stairs. I couldn’t drive. I couldn’t play with my grandkids. So when this opportunity came to me I was taking it.”

    Now, she says, she’s feeling “great today compared to other days.” 

    Dr. Robert Montgomery, NYU Langone Transplant Institute director, said she is currently “doing very well” in recovery. 

    Pisano received only the second known transplant of a gene-edited pig kidney into a living person, and the first to include the pig’s thymus gland to aid against rejection, the hospital said. The transplant surgery took place on April 12, eight days after the heart pump, called a left ventricular assist device, or LVAD, was implanted on April 4.

    Last month, surgeons at Massachusetts General Hospital in Boston transplanted a pig kidney into 62-year-old Rick Slayman, marking the first successful procedure of its kind in a living human patient in the world. 

    Rejection issues with animal-to-human transplants, or xenotransplantation, have led to failures, largely due to people’s immune systems attacking the foreign tissue. Now, scientists are using genetic modification to better match those organs to humans.

    “The human immune system rejects organs from animals, but Dr. Montgomery and his team used a pig kidney with one gene altered to make it more compatible,” LaPook explains.

    Montgomery says this is about more than just the organ itself.

    “This isn’t just about keeping somebody alive, it’s restoring them to their their lives,” he says. 

    For Pisano, it means dreams of playing with her two young grandchildren for the first time in years, she says.

    LaPook adds this procedure was done under the FDA’s “compassionate use” protocol. “So it’s not approved yet — but what an amazing technological tour de force,” he said. 

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  • Organs from Cannabis Consumers Don’t Pose Risks of Infection | High Times

    Organs from Cannabis Consumers Don’t Pose Risks of Infection | High Times

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    A study published in the American Journal of Transplantation recently shows that organs that come from donors with a history of recent cannabis use don’t show signs of infection or significant risk.

    The study was conducted by a handful of researchers from University of California, San Francisco, University of Pennsylvania, and Temple University, and funded by National Institutes of Health, the Centers for Disease Control and Prevention (CDC), and Transplant Foundation Innovative Research Grant Program. Researchers examined information from three specific transplant centers located in Philadelphia, Pennsylvania, between transplants that were conducted by the Gift of Life Program between January 1, 2015-June 30, 2016.

    According to the CDC, organ transplant patients take anti-rejection medicine that lowers their body’s immune system response, which helps their bodies accept the new organ. That same medicine can sometimes lead to mild or life-threatening infections, which can develop days, weeks, months, or even years after transplant surgery occurs.

    The authors explained that cannabis leaves sometimes contain harmful bacteria or fungi, and inhaled cannabis has also been found in relation to infections in transplant patients. This study addressed the question regarding if cannabis consumer’s organs are harmful to patients on the organ receiving end. “The goal of our study is to better characterize the infection risks that marijuana use among deceased organ donors may pose to [solid organ transplants] recipients,” the authors wrote.

    The authors explained the importance of their findings amidst the rising percentage of people consuming cannabis regularly. “It is likely that a growing proportion of deceased organ donors have a history of marijuana use, as well, though this metric has not been specifically reported,” authors said.

    The study examined donors with cannabis use within the last 12 months prior to the study, as well as donors with no recent cannabis use history. “Despite concern that donor exposure to marijuana increases the risk of fungal infection in recipients, our study found that a donor history of marijuana use did not increase (1) the likelihood of donor culture positivity (including respiratory cultures), or (2) the risk of early recipient bacterial or fungal infection, graft failure, or death posttransplant,” the study stated. “Even when evaluating only lung recipients, there remained no association between donor marijuana use and the risk of posttransplant infection.”

    The researchers explored a variety of data from the three transplant facilities, such as donors who experienced bacterial or fungal infections, or if the transplant failed and led to death in the patient. Overall, organs from consumers with recent cannabis use posed little threat to the patients. “Among donors with a history of recent marijuana use, 79 (89%) had at least 1 positive culture, compared to 264 (87%) among those with no history of marijuana use,” researchers wrote. “On donor respiratory cultures, 76 (85%) donors with a history of recent marijuana use and 250 (82%) donors with no history of recent marijuana use had bacterial or fungal growth on respiratory cultures. On both unadjusted analyses and multivariable analyses, there was no association between recent donor marijuana use and donor culture positivity.”

    However, it’s important to note that the data that researchers reviewed was collected well after transplants occurred, and relied on next-of-kin to help measure a patient’s cannabis use. This was described as an “imperfect measure” of data collection.

    “In conclusion, our study demonstrates that donors with a history of recent marijuana use are not more likely to have positive donor cultures, and their recipients are not more likely to develop a bacterial or fungal infection, graft failure, or death in the early posttransplant period (in the context of current management),” the study concluded. “These results suggest that organs from donors with a history of recent marijuana use do not pose significant novel infectious risks to recipients in the early posttransplant period.”

    Currently, medical cannabis patients often experience discrimination when seeking out health care, but specifically encounter restrictions when it comes to organ transplants, according to a report published by the Petrie-Flom Center at Harvard Law School last October. “Many transplant centers prevent cannabis users from receiving solid organ transplantation due to concerns regarding interactions between cannabis and immunosuppressant drugs used for transplants, treatment non-adherence, fungal infections, and neuropsychiatric effects,” the report stated. As a result, medical cannabis patients are often ineligible for transplant.

    The review adds that larger-scale studies are needed in order to determine if medical cannabis consumption “…should not be an absolute contraindication to solid organ transplantation.” Furthermore, some research shows evidence of medical cannabis helping to prevent transplant rejection in some patients.

    Last year, another study found that cannabis use isn’t a risk for liver transplant patients. Researchers found no correlation between cannabis and non-cannabis users, stating that there was “no statistically significant associations between marijuana use with post-transplant bacterial or fungal infections, medication non-compliance, or continued substance use.”

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    Nicole Potter

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  • US surgeons transplant genetically modified pig kidney into patient

    US surgeons transplant genetically modified pig kidney into patient

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    NEW YORK — Doctors in Boston announced Thursday they have transplanted a pig kidney into a 62-year-old patient.

    Massachusetts General Hospital said it’s the first time a genetically modified pig kidney has been transplanted into a living person. Previously, pig kidneys have been temporarily transplanted into brain-dead donors. Also, two men received heart transplants from pigs, although both died within months.

    The experimental transplant was done at the Boston hospital on Saturday. The patient, Richard “Rick” Slayman of Weymouth, Massachusetts, is recovering well and is expected to be discharged soon, doctors said Thursday.

    Slayman had a kidney transplant at the hospital in 2018, but had to go back on dialysis last year when it showed signs of failure. When dialysis complications arose, his doctors suggested a pig kidney transplant, he said in a statement released by the hospital.

    “I saw it not only as a way to help me, but a way to provide hope for the thousands of people who need a transplant to survive,” said Slayman.

    The announcement marks the latest development in xenotransplantation, the term for efforts to try to heal human patients with cells, tissues, or organs from animals. For decades, it didn’t work – the human immune system immediately destroyed foreign animal tissue. More recent attempts have involved pigs that have been modified so their organs are more humanlike – increasing hope that they might one day help fill a shortage of donated organs.

    More than 100,000 people are on the national waiting list for a transplant, most of them kidney patients, and thousands die every year before their turn comes.

    ___

    The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.

    Copyright © 2024 by The Associated Press. All Rights Reserved.

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    AP

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