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Tag: Novel Coronaviruses

  • CDC shoots down false claims it will mandate COVID-19 vaccines for schoolchildren, saying states make that decision

    CDC shoots down false claims it will mandate COVID-19 vaccines for schoolchildren, saying states make that decision

    The Centers for Disease Control and Prevention has refuted claims that it’s planning to add the COVID-19 vaccine to immunization schedules for schoolchildren, saying that the authority for that decision lies with states and other local entities.

    The false claim spread after it was shared by Fox News host Tucker Carlson in a tweet this week, as the Associated Press reported. 

    Carlson tweeted that the agency would make the vaccine mandatory in order for children to attend school, a claim the CDC quickly shot down. While an advisory committee to the CDC voted to recommend that the vaccine be added to immunization schedules, the CDC “only makes recommendations for use of vaccines, while school-entry vaccination requirements are determined by state or local jurisdictions,” CDC spokeswoman Kate Grusich told the AP.

    Grusich explained that the action was meant to streamline clinical guidance for healthcare providers by adding COVID-19 vaccines to a single list of all currently licensed, authorized and routinely recommended vaccines.

    “It’s important to note that there are no changes in COVID-19 vaccine policy,” she said.

    The news comes as U.S. known cases of COVID are continuing to ease and now stand at their lowest level since mid-April, although the true tally is likely higher given how many people overall are testing at home, where data are not being collected.

    The daily average for new cases stood at 38,077 on Thursday, according to a New York Times tracker, down 8% from two weeks ago. Cases are currently rising in 14 states, as well as Washington, D.C., and Puerto Rico.

    The daily average for hospitalizations was down 2% to 26,669, although hospitalizations are rising in almost all northeastern states as cold weather arrives. The daily average for deaths was down 7% to 360.

    Coronavirus Update: MarketWatch’s daily roundup has been curating and reporting all the latest developments every weekday since the coronavirus pandemic began

    Other COVID-19 news you should know about:

    • Pfizer
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    +4.42%

    is planning to sell the COVID vaccine it developed with German partner BioNTech
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    +9.88%

    for $110 -$130 a dose once the U.S. market for COVID-19 shots becomes commercial, likely in the first quarter of next year, MarketWatch’s Jaimy Lee reported. Pfizer and BioNTech are currently paid $30.50 per vaccine dose by the U.S. government, which contracted with the companies, as well as with other vaccine makers like Moderna
    MRNA,
    +9.07%

    and Novavax
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    +11.35%
    ,
    and then made the COVID-19 shots available at no cost to people in the U.S. during the public-health emergency. The emergency declaration in the U.S. isn’t expected to be renewed next year, which will lead to the formation of an official commercial market for COVID-19 vaccines, tests and treatments. 

    • Johnson & Johnson
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    said the volume of surgical procedures is returning to prepandemic levels in many parts of the world, a trend that cheered Wall Street and could bode well for other medical-technology heavyweights like Stryker Corp.
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    +0.57%

    and Zimmer Biomet Holdings
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    .
    J&J, which reported earnings this week, said its medical-technology business had a “strong September,” with U.S. sales of hip and knee implants and other surgical devices rising 7.7% to $3.3 billion in the third quarter of the year. “We are seeing procedures recovering,” Ashley McEvoy, worldwide chair of J&J’s MedTech business, told investors during this week’s earnings call. “In the U.S., we started to see surgical procedures tick up, predominantly at the latter part of the quarter.”

    The new bivalent vaccine might be the first step in developing annual COVID shots, which could follow a similar process to the one used to update flu vaccines every year. Here’s what that process looks like, and why applying it to COVID could be challenging. Illustration: Ryan Trefes

    • “As China’s ruling Communist Party holds a congress this week, many Beijing residents are focused on an issue not on the formal agenda: Will the end of the meeting bring an easing of China’s at times draconian ‘zero-COVID’ policies that are disrupting lives and the economy?” the AP reported. It appears to be wishful thinking. As the world moves to a postpandemic lifestyle, many across China have resigned themselves to lining up several times a week for COVID tests, restrictions on travel to other regions and the ever-present possibility of a community lockdown.

    • Fantasy Fest, a 10-day annual party, is kicking off in Key West, Fla., on Friday, with a full slate of events for the first time since the pandemic started, the AP reported. “Due to the COVID pandemic, this will be the first full Fantasy Fest since 2019,” the festival’s board chair, Steve Robbins, said. “So I know our guests and staff are excited about getting back to the real Fantasy Fest.” Dozens of themed events are set for the festival, including a nighttime parade Oct. 29 featuring floats and elaborately costumed marching groups. Participants are encouraged to draw costume ideas from the festival’s theme, “Cult Classics & Cartoon Chaos,” and to portray characters inspired by favorite cartoons and television or film productions with a cult following.

    Here’s what the numbers say:

    The global tally of confirmed cases of COVID-19 topped 626.9 million on Friday, while the death toll rose above 6.57 million, according to data aggregated by Johns Hopkins University.

    The U.S. leads the world with 97.2 million cases and 1,067,190 fatalities.

    The Centers for Disease Control and Prevention’s tracker shows that 226.5 million people living in the U.S., equal to 68.2% of the total population, are fully vaccinated, meaning they have had their primary shots. Just 111.4 million have had a booster, equal to 49.1% of the vaccinated population, and 26.8 million of those who are eligible for a second booster have had one, equal to 40.6% of those who received a first booster.

    The CDC reports that some 19.4 million people have had a dose of the updated bivalent booster that targets omicron and its subvariants along with the original virus.

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  • Pfizer sets new prices for its COVID-19 vaccines. The cost? $110 to $130 per dose

    Pfizer sets new prices for its COVID-19 vaccines. The cost? $110 to $130 per dose

    Pfizer Inc.
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    said Thursday that it plans to sell the COVID-19 shot it developed with BioNTech SE
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    +7.14%

    for $110 to $130 per dose once the U.S. market for COVID-19 shots becomes commercial, likely in the first quarter of next year.

    Pfizer and BioNTech are currently paid $30.50 per vaccine dose by the U.S. government, which contracted with the companies (as well as other vaccine makers like Moderna Inc.
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    +6.57%

    and Novavax Inc.
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    +8.88%

    ) and then made the COVID-19 shots available at no cost to people in the U.S. during the public-health emergency.

    The emergency declaration in the U.S. isn’t expected to be renewed next year, which will lead to the formation of an official commercial market for COVID-19 vaccines, tests and treatments. That said, this change doesn’t mean most Americans will be on the hook to pay for their shots in 2023 and beyond.

    A recent Kaiser Family Foundation analysis said most people with private insurance won’t be expected to pay anything out of pocket for the vaccines, though the costs may eventually be baked into the price of health-insurance premiums, as is done with flu shots. People with Medicare will have their shots covered by Medicare Part B, while those with Medicaid should also have coverage of COVID-19 vaccines. It’s the uninsured who may find it difficult to find free vaccines and boosters in the future.

    Wall Street analysts cheered the news, saying Pfizer’s pricing plan came in above expectations. It also bodes well for Moderna’s stock. SVB Securities upgraded the company to market perform from underperform, though the company has not yet announced its pricing plans for its COVID-19 shots.

    “Presuming that MRNA prices as a rational duopolist, this substantially improves the company’s ability to meet 2023 revenue guidance,” SVB analyst Mani Foroohar told investors.

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  • Two new COVID variants are spreading fast in New York region and could account for about 37% of new cases

    Two new COVID variants are spreading fast in New York region and could account for about 37% of new cases

    The two newly identified omicron subvariants, dubbed BQ.1 and BQ.1.1, are spreading fast in the New York region and could account for about 37% of new cases, according to Centers for Disease Control and Prevention data crunched by NBC News.

    The two variants accounted for 11.5% and 8% of new cases, respectively, that were recorded in the area in the week ending Oct. 15, up from 4.1% and 1.9% two weeks earlier. The New York area includes New Jersey, Puerto Rico and the Virgin Islands.

    Combined, they accounted for 11.4% of overall U.S. cases in the same week. Before last Friday’s data release, they were included in BA.5 variant data, as the numbers were too small to break out. BQ.1 was first identified by researchers in early September and has been found in the U.K. and Germany, among other places. The CDC is updating the numbers every Friday.

    “When you get variants like that, you look at what their rate of increase is as a relative proportion of the variants, and this has a pretty troublesome doubling time,” Anthony Fauci, President Joe Biden’s chief medical adviser, said in an interview with CBS News earlier this week.

    The news comes as experts fear another wave of cases during the winter months as colder weather forces people indoors and families gather for holidays.

    U.S. known cases of COVID are continuing to ease and now stand at their lowest level since mid-April, although the true tally is likely higher given how many people overall are testing at home, where the data are not being collected.

    The daily average for new cases stood at 37,888 on Tuesday, according to a New York Times tracker, down 15% from two weeks ago. Cases are currently rising in 10 states: Nevada, New Hampshire, New Mexico, Oklahoma, Maryland, Wisconsin, Illinois, Vermont, Kansas and Florida. Cases are also rising in Washington, D.C.

    The daily average for hospitalizations was down 6% to 25,845, although hospitalizations are up in many northeastern states, including Rhode Island, New Hampshire, New Jersey, New York, Massachusetts, Delaware, Pennsylvania and Maine.

    The daily average for deaths is down 3% to 382.

    In other news, the World Health Organization said its emergency committee came away from a meeting last week with the determination that the pandemic remains a global health emergency, despite recent progress.

    WHO Director General Tedros Adhanom Ghebreyesus said he agreed with that decison.

    “The committee emphasized the need to strengthen surveillance and expand access to tests, treatments and vaccines for those most at-risk, and for all countries to update their national preparedness and response plans,” Tedros told reporters at a briefing.

    “While the global situation has obviously improved since the pandemic began, the virus continues to change, and there remain many risks and uncertainties,” he said. “This pandemic has surprised us before and very well could again.”

    The new bivalent vaccine might be the first step in developing annual COVID-19 shots, which could follow a similar process to the one used to update flu vaccines every year. Here’s what that process looks like, and why applying it to COVID could be challenging. Illustration: Ryan Trefes

    Coronavirus Update: MarketWatch’s daily roundup has been curating and reporting all the latest developments every weekday since the coronavirus pandemic began

    Other COVID-19 news you should know about:

    • Reports that a 16-year-old girl has died at a COVID quarantine center in China are causing anger after her family said their pleas for medical help were ignored, the Guardian reported. Videos of the girl have spread across Chinese social media in the last 24 hours. The distressing footage, which the Guardian said it has not been able to independently verify, shows the teenager ill, struggling to breathe and convulsing in a bunk bed at what is purported to be a quarantine center in Ruzhou, Henan province. The reports come as Communist Party leaders hold their party congress in Beijing amid anger about the country’s strict zero-COVID policy.

    • Hong Kong, which is experiencing a massive brain drain thanks to the pandemic and to political upheaval, unveiled a new visa scheme on Wednesday that aims to attract global talent, the Associated Press reported. The region’s chief executive, John Lee, said the Top Talent Pass Scheme will allow people who earn an annual salary of 2.5 million Hong Kong dollars ($318,472) or more, as well as graduates of the world’s top universities, to work or pursue opportunities in the city for two years.

    In a rare display of defiance, two banners unfurled from a highway overpass in Beijing condemned Chinese President Xi Jinping and his strict COVID policies. The protest took place days before the Communist Party congress in that city.

    • The COVID pandemic catalyzed a major shift in the way Americans live and work, and a new analysis from the Federal Reserve Bank of New York shows that workers in the U.S. are taking advantage of the widespread shift toward remote work to spend more time sleeping and engaging in leisure activities, MarketWatch’s Chris Matthews reported. “One of the most enduring shifts [resulting from the pandemic] has occurred in the workplace, with millions of employees making the switch to work from home,” wrote David Dam, a former New York Fed research analyst, in a Tuesday blog post.

    • The North Dakota Department of Health stored thousands of COVID-19 vaccine doses at incorrect temperatures or without temperature data over the past two years, according to a state audit Tuesday that said some of those vaccines were administered to patients, the AP reported. The health department disputed the findings. Tim Wiedrich, who heads the agency’s virus response, said “no non-viable vaccine” was given to patients. In responses that accompanied the audit, the department said clerical errors or other errors of documentation erroneously suggested that expired or bad doses were given.

    Here’s what the numbers say:

    The global tally of confirmed cases of COVID-19 topped 625.7 million on Wednesday, while the death toll rose above 6.57 million, according to data aggregated by Johns Hopkins University.

    The U.S. leads the world with 97 million cases and 1,065,841 fatalities.

    The Centers for Disease Control and Prevention’s tracker shows that 226.2 million people living in the U.S., equal to 68.1% of the total population, are fully vaccinated, meaning they have had their primary shots. Just 110.8 million have had a booster, equal to 49% of the vaccinated population, and 25.6 million of those who are eligible for a second booster have had one, equal to 39% of those who received a first booster.

    Some 14.8 million people have had a dose of the updated bivalent booster that targets omicron and its subvariants along with the original virus.

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  • CDC identifies new COVID variants that accounted for 11.4% of new cases in week ending Oct. 15

    CDC identifies new COVID variants that accounted for 11.4% of new cases in week ending Oct. 15

    The Centers for Disease Control and Prevention said a new COVID variant dubbed BQ.1 and a descendant called BQ.1.1 have gained traction in the U.S., accounting for 11.4% of new cases across the nation in the week ending Oct. 15.

    The two variants are lineages of BA.5, the omicron subvariant that remains dominant but has shrunk to account for just 67.9% of circulating variants, the agency said in a Friday update. The CDC had previously combined BQ.1 and BQ.1.1 with BA.5 cases because the numbers of the new variants were so small. BQ.1 was first identified by researchers in early September and has been found in the U.K. and Germany, among other places.

    New York and New Jersey currently have the highest proportion of BQ.1 and BQ.1.1 infections, at about 20% of overall cases, according to CDC estimates.

    “When you get variants like that, you look at what their rate of increase is as a relative proportion of the variants, and this has a pretty troublesome doubling time,” Anthony Fauci, President Joe Biden’s chief medical adviser, said in an interview with CBS News. 

    Adding to concerns, the variant seems “to elude important monoclonal antibodies,” he added.

    Fauci is confident that Moderna
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    ,
    as well as Pfizer
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    and German partner BioNTech
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    ,
    will be able to update boosters to target the new subvariant. “The somewhat encouraging news is that it’s a BA.5 sublineage, so there are almost certainly going to be some cross-protections that you can boost up,” he said.

    So far, only 14.8 million people living in the U.S. have taken advantage of the new bivalent boosters that were authorized by the Food and Drug Administration in late August. That’s equal to about 7% of the 209 million who were initially eligible.

    The FDA authorized the Pfizer booster for use in people aged 12 and older and the Moderna booster for adults aged 18 and older. Last week, the FDA added children aged 5 to 11 to the Pfizer program and children aged 6 through 17 to the Moderna one.

    Experts are concerned that the low number of vaccinations is due to a sense that the pandemic is over and no longer poses a major risk for most people. U.S. cases are steadily declining and now stand at their lowest level since mid-April; however, the true tally is likely higher than the official count, because many people are testing at home, where data are not being collected.

    The daily average for new cases stood at 37,649 on Sunday, down 19% from two weeks ago, according to a New York Times tracker.

    The daily average for hospitalizations was down 5% to 26,475, while the daily average for deaths was down 8% to 374.

    But cold weather is expected to bring a new wave of cases, and hospitalizations are rising again in much of the Northeast, the Times tracker is showing.

    “That’s the thing that’s so frustrating for me and for my colleagues who are involved in this, is that we have the capability of mitigating against this. And the uptake of the new bivalent vaccine is not nearly as high as we would like it to be,” said Fauci.

    Coronavirus Update: MarketWatch’s daily roundup has been curating and reporting all the latest developments every weekday since the coronavirus pandemic began

    Other COVID-19 news you should know about:

    • Moderna and Gavi, the Vaccine Alliance, which is supplying vaccines to low- and middle-income countries, have agreed to cancel remaining orders under their 2022 COVID-19 vaccine agreement given “sufficient supply.” The biotechnology company has supplied Gavi with nearly 70 million doses of COVID-19 vaccines, in addition to facilitating the donation of more than 100 million doses. Moderna and Gavi said they will create a new framework that enables Gavi to buy up to 100 million COVID-19 vaccine doses in 2023. 

    • The World Health Organization, the Food and Agriculture Organization of the United Nations, the United Nations Environment Program and the World Organization for Animal Health on Monday launched a new initiative that aims to address health threats to humans, animals, plants and the environment. The One Health Joint Plan of Action “aims to create a framework to integrate systems and capacity so that we can collectively better prevent, predict, detect, and respond to health threats,” the four agencies said in a statement.

    • China is doubling down on its zero-COVID strategy as a historic Communist Party congress opens in Beijing, BBC News reported. Zero COVID was a “people’s war to stop the spread of the virus,” said President Xi Jinping as he kicked off the meeting. There is increasing public fatigue over lockdowns and travel restrictions, and Beijing has come under strict security measures ahead of the congress, sparking frustration in the city, including a rare and dramatic public protest on Thursday criticizing Xi and his strategy.

    In a rare display of defiance, two banners were unfurled from a highway overpass in Beijing condemning Chinese President Xi Jinping and his strict COVID-19 policies. The protest took place days before the expected extension of Xi’s tenure.

    • Airline stocks rallied Monday after data showed that on Sunday, more people flew than on any other day since before the pandemic. Data from the Transportation Security Administration showed that 2.495 million travelers went through TSA checkpoints on Sunday, which is just above the previous 2022 high of 2.490 million on July 1 and the most since Feb. 11, 2020, which was exactly one month before the World Health Organization declared COVID-19 a global pandemic. In comparison, the day with the fewest travelers since the start of the pandemic was April 12, 2022, with 87,534 people traveling. And in 2019, there were 116 days of more travelers than Sunday, while the average for that year was 2.306 million. The U.S. Global Jets ETF
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     was up 2.2%.

    Here’s what the numbers say:

    The global tally of confirmed cases of COVID-19 topped 624.7 million on Monday, while the death toll rose above 6.56 million, according to data aggregated by Johns Hopkins University.

    The U.S. leads the world with 96.9 million cases and 1,065,118 fatalities.

    The Centers for Disease Control and Prevention’s tracker shows that 226.2 million people living in the U.S., equal to 68.1% of the total population, are fully vaccinated, meaning they have had their primary shots. Just 110.8 million have had a booster, equal to 49% of the vaccinated population, and 25.6 million of those who are eligible for a second booster have had one, equal to 39% of those who received a first booster.

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  • Study finds Paxlovid can interact badly with some heart medications, and White House renews COVID emergency through Jan. 11

    Study finds Paxlovid can interact badly with some heart medications, and White House renews COVID emergency through Jan. 11

    A new study has found that the COVID antiviral Paxlovid can interact badly with certain heart medications, raising concerns for patients with cardiovascular risk who test positive.

    The study was published in the Journal of the American College of Cardiology and found the reaction involved such medications as blood thinners and statins. As patients who are hospitalized with COVID are at elevated risk of heart problems, they are likely to be described Paxlovid, which was developed by Pfizer
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    .

     “Co-administration of NMVr (Paxlovid) with medications commonly used to manage cardiovascular conditions can potentially cause significant drug-drug interactions and may lead to severe adverse effects,” the authors wrote. “It is crucial to be aware of such interactions and take appropriate measures to avoid them.”

    The news comes just days after the White House made a renewed push to encourage Americans above the age of 50 to take Paxlovid or use monoclonal antibodies if they test positive and are at risk of developing severe disease.

    White House coordinator Dr. Ashish Jha told the New York Times that greater use of the medicine could reduce the average daily death count to about 50 a day from close to 400 currently.

    “I think almost everybody benefits from Paxlovid,” Jha said. “For some people, the benefit is tiny. For others, the benefit is massive.” 

    Yet a smaller share of 80-year-olds with COVID in the U.S. is taking it than 45-year-olds, Jha said, citing data said he has seen.

    On Thursday, the White House extended its COVID pubic health emergency through Jan. 11 as it prepares for an expected rise in cases in the colder months, the Associated Press reported.

    The public health emergency, first declared in January 2020 and renewed every 90 days since, has dramatically changed how health services are delivered.

    The declaration enabled the emergency authorization of COVID vaccines, as well as free testing and treatments. It expanded Medicaid coverage to millions of people, many of whom will risk losing that coverage once the emergency ends. It temporarily opened up telehealth access for Medicare recipients, enabling doctors to collect the same rates for those visits and encouraging health networks to adopt telehealth technology.

    Since the beginning of this year, Republicans have pressed the administration to end the public health emergency.

    President Joe Biden, meanwhile, has urged Congress to provide billions more in aid to pay for vaccines and testing. Amid Republican opposition to that request, the federal government ceased sending free COVID tests in the mail last month, saying it had run out of funds for that effort.

    Separately, the head of the World Health Organization urged countries to continue to surveil, monitor and track COVID and to ensure poorer countries get access to vaccines, diagnostics and treatments, reiterating that the pandemic is not yet over.

    Tedros Adhanom Ghebreyesus said most countries no longer have measures in place to limit the spread of the virus, even though cases are rising again in places including Europe.

    “Most countries have reduced surveillance drastically, while testing and sequencing rates are also much lower,” Tedros said in opening remarks at the IHR Emergency Committee on COVID-19 Pandemic on Thursday.

    “This,” said the WHO leader, “is blinding us to the evolution of the virus and the impact of current and future variants.”

    U.S. known cases of COVID are continuing to ease and now stand at their lowest level since late April, although the true tally is likely higher given how many people overall are testing at home, where the data are not being collected.

    The daily average for new cases stood at 38,530 on Thursday, according to a New York Times tracker, down 19% from two weeks ago. Cases are rising in six states, namely Nevada, New Mexico, Kansas, Maine, Wisconsin and Vermont, and are flat in Wyoming. They are falling everywhere else.

    The daily average for hospitalizations was down 7% at 26,665, while the daily average for deaths is down 7% to 377. 

    The new bivalent vaccine might be the first step in developing annual Covid shots, which could follow a similar process to the one used to update flu vaccines every year. Here’s what that process looks like, and why applying it to Covid could be challenging. Illustration: Ryan Trefes

    Coronavirus Update: MarketWatch’s daily roundup has been curating and reporting all the latest developments every weekday since the coronavirus pandemic began

    Other COVID-19 news you should know about:

    • Federal Health Minister Karl Lauterbach has urged German states to reintroduce face-mask requirements for indoor spaces due to high COVID cases numbers, the Local.de reported. Lauterbach was launching his ministry’s new COVID campaign on Friday. “The direction we are heading in is not a good one,” he said at a press conference in Berlin, adding it’s better to take smaller measures now than be forced into drastic ones later.

    • Health officials in Washington and Oregon said Thursday that a fall and winter COVID surge is likely headed to the Pacific Northwest after months of relatively low case levels, the AP reported. King County (Wash.) Health Officer Dr. Jeff Duchin said during a news briefing that virus trends in Europe show a concerning picture of what the U.S. could soon see, the Seattle Times reported.

    Two banners unfurled from a highway overpass in Beijing condemned Chinese President Xi Jinping and his strict Covid policies, in a rare display of defiance. The protest took place days before the expected extension of the leader’s tenure.

    • Kevin Spacey’s trial on sexual-misconduct allegations will continue without a lawyer who tested positive for COVID on Thursday, Yahoo News reported. The “American Beauty” and “House of Cards” star is on trial in Manhattan federal court facing allegations in a $40 million civil lawsuit that he preyed upon actor Anthony Rapp in 1986 when Rapp was 14 and Spacey was 26. Jennifer Keller’s diagnosis comes after she spent about five hours cross-examining Rapp on the witness stand over two days — a few feet away from the jury box without wearing a mask.

    • A man who presents himself as an Orthodox Christian monk and an attorney with whom he lived fraudulently obtained $3.5 million in federal pandemic relief funds for nonprofit religious organizations and related businesses they controlled, and spent some of it to fund a “lavish lifestyle,” federal prosecutors said Thursday. Brian Andrew Bushell, 47, and Tracey M.A. Stockton, 64, are charged with conspiracy to commit wire fraud and unlawful monetary transactions, the U.S. attorney’s office in Boston said in a statement, as reported by the AP.

    Here’s what the numbers say:

    The global tally of confirmed cases of COVID-19 topped 623.9 million on Monday, while the death toll rose above 6.56 million, according to data aggregated by Johns Hopkins University.

    The U.S. leads the world with 96.9 million cases and 1,064,821 fatalities.

    The Centers for Disease Control and Prevention’s tracker shows that 226.2 million people living in the U.S., equal to 68.1% of the total population, are fully vaccinated, meaning they have had their primary shots. Just 110.8 million have had a booster, equal to 49% of the vaccinated population, and 25.6 million of those who are eligible for a second booster have had one, equal to 39% of those who received a first booster.

    Some 14.8 million people have had a shot of the new bivalent booster that targets the new omicron subvariants.

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  • Large number of U.S. COVID deaths could be prevented if patients would take Pfizer’s Paxlovid, White House coordinator warns

    Large number of U.S. COVID deaths could be prevented if patients would take Pfizer’s Paxlovid, White House coordinator warns

    A large number of U.S. COVID deaths could be prevented if patients would take Paxlovid, the antiviral developed by Pfizer
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    that helps reduce the risk of hospitalization and death, according to White House COVID coordinator Dr. Ashish Jha.

    Jha told the New York Times that the average daily death count could be reduced to about 50 a day from 400 currently, if every American aged 50 and above that tests positive for the virus took a course of either Paxlovid or used monoclonal antibodies.

     “The public doesn’t seem to understand that the evidence around hospitalization and deaths is really powerful,” Dr. Robert Wachter, chair of medicine at the University of California in San Francisco told the paper.

    The issue seems to be a combination of worry about certain issues that Paxlovid can cause, including a strange metallic taste and the potential for “rebound COVID,” where patients quickly become reinfected after the five-day course of pills has been completed. That happened to both President Joe Biden and first lady Jill Biden recently.

    The second reason is that many Americans — and Republicans, in particular — have refused to take COVID seriously and are not willing to take steps to reduce its impact. Trials have found Paxlovid to be effective across all age groups, but mostly among older patients. But as the COVID death rate for people under 50 is already close to zero, reducing it in a statistically significant way is difficult.

    See now: CDC scraps travel health notices as countries slow testing, and study confirms Republican-leaning counties suffered more COVID deaths than Democrat-leaning ones

    “I think almost everybody benefits from Paxlovid,” Jha said. “For some people, the benefit is tiny. For others, the benefit is massive.” 

    Yet a smaller share of 80-year-olds with COVID in the U.S. is taking it than 45-year-olds, Jha said citing data he has seen.

    From the CDC: Stay Up to Date with COVID-19 Vaccines Including Boosters

    The news comes as U.S. known cases of COVID are continuing to ease and now stand at their lowest level since late April, although the true tally is likely higher given how many people are testing at home, with data generally not being collected.

    The daily average for new cases stood at 41,605 on Thursday, according to a New York Times tracker, down 25% from two weeks ago. Cases are declining in northeastern states including New York and New Jersey, while cases are rising in the western states Montana, Washington and Oregon.

    The daily average for hospitalizations was down 11% at 27,021, while the daily average for deaths is down 8% to 391.

    Coronavirus Update: MarketWatch’s daily roundup has been curating and reporting all the latest developments every weekday since the coronavirus pandemic began

    Other COVID-19 news you should know about:

    • Molnupiravir, the COVID pill developed by Merck
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    +0.18%

    and privately held Ridgeback Therapeutics, produced mixed results in two recent studies, the companies said Thursday. Early data from a trial conducted in the U.K. by the University of Oxford found no evidence of a difference when molnupiravir was added to usual care in reducing hospitalizations and death. A second study conducted in Israel found a benefit in patients who were 65 and older, but no benefit for 40- to 60-year-olds.

    • Homelessness is surging in the U.S. again as pandemic programs that halted evictions are being phased out, the Associated Press reported. The overall number of homeless people in a federal report to be released in the coming months is expected to be higher than the 580,000 unhoused before the coronavirus outbreak, the National Alliance to End Homelessness said. The AP tallied results from city-by-city surveys conducted earlier this year and found the number of people without homes is up overall compared with 2020 in areas reporting results so far.

    • The idea was to have China in stable and tip-top shape when thousands of delegates gather in Beijing to usher in a historic third term in power for Xi Jinping, BBC News reported. However, the coronavirus is not playing nicely. In recent weeks, tens of millions of people have again been confined to their homes in lockdowns across 60 towns and cities, and this is bringing political pressure on the man who has become the most powerful Chinese figure since the first communist-era leader, Mao Zedong.

    Covid-19 lockdowns, corruption crackdowns and more have put China’s economy on a potential crash course. WSJ’s Dion Rabouin explains how China’s economic downturn could harm the U.S. and the rest of the world. Illustration: David Fang

    • A new COVID-19 wave appears to be brewing in Europe as cooler weather arrives, with public health experts warning that vaccine fatigue and confusion over types of available vaccines will likely limit booster uptake, Reuters reported. The omicron subvariants BA.4 and BA.5 that dominated this summer are still behind the majority of infections, but newer omicron subvariants are gaining ground. Hundreds of new forms of omicron are being tracked by scientists, the World Health Organization said this week.

    Here’s what the numbers say:

    The global tally of confirmed cases of COVID-19 topped 620.5 million on Friday, while the death toll rose above 6.55 million, according to data aggregated by Johns Hopkins University.

    The U.S. leads the world with 96.6 million cases and 1,062,130 fatalities.

    The Centers for Disease Control and Prevention’s tracker shows that 225.8 million people living in the U.S., equal to 68% of the total population, are fully vaccinated, meaning they have had their primary shots. Just 110.5 million have had a booster, equal to 48.9% of the vaccinated population, and 24.8 million of those who are eligible for a second booster have had one, equal to 37.9% of those who received a first booster.

    Some 11.5 million people have had a shot of the new bivalent booster that targets the new omicron subvariants.

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  • U.S. risks prolonging pandemic if it doesn’t back WTO push to get vaccines and treatments to lower-income countries, lawmakers warn

    U.S. risks prolonging pandemic if it doesn’t back WTO push to get vaccines and treatments to lower-income countries, lawmakers warn

    The U.S. is at risk of prolonging the COVID pandemic if it fails to back an initiative that aims to get vaccines, diagnostics and treatments to lower-income countries, a congressional group has told President Joe Biden.

    In a letter to Biden from the group led by Earl Blumenauer, a Democrat from Oregon, the group urged him to back the World Trade Organization’s agreement in June to ease exports of lifesaving therapies.

    With more than 600 million shots in arms, 21,500 free testing sites, the ability to order at-home tests for free, and more treatments available now than at any point in the pandemic, the outlook in the United States is better than ever. Unfortunately, however, the prospect for many low-income countries is not so positive — putting the United States’ own success in jeopardy,” the lawmakers wrote.

    The letter was sent ahead of a meeting of the WTO council for trade-related aspects of IP rights that is due to kick off Thursday.

    The group noted that lower-income countries are facing a higher risk of severe illness, hospitalization and death as only a small percentage of their populations are vaccinated. Just 19% of people in those countries are vaccinated, compared with about 75% in high-income countries, according to the Multilateral Leaders Taskforce on COVID-19, a joint initiative of the International Monetary Fund, the World Bank, the World Health Organization and the WTO.

    U.S. known cases of COVID are continuing to ease and now stand at their lowest level since late April, although the true tally is likely higher given how many people are testing at home, where the data are not being collected.

    The daily average for new cases stood at 43,149 on Wednesday, according to a New York Times tracker, down 23% from two weeks ago. Cases are rising in most northeastern states by 10% of more, while cases in the western states Montana, Washington and Oregon are rising.

    The daily average for hospitalizations was down 11% at 27,184, while the daily average for deaths is down 8% to 391. 

    The new bivalent vaccine might be the first step in developing annual Covid shots, which could follow a similar process to the one used to update flu vaccines every year. Here’s what that process looks like, and why applying it to Covid could be challenging. Illustration: Ryan Trefes

    Coronavirus Update: MarketWatch’s daily roundup has been curating and reporting all the latest developments every weekday since the coronavirus pandemic began

    Other COVID-19 news you should know about:

    • China’s huge Xinjiang region has been hit with sweeping COVID travel restrictions ahead of a key Communist Party congress later this month, the Associated Press reported. Trains and buses in and out of the region of 22 million people have been suspended, and passenger numbers on flights have been reduced to 75% of capacity in recent days, according to Chinese media reports. The region is home to minorities who have been forced into prison-like re-education centers to force them to renounce their religion, typically Islam, and allegedly subjected to human-rights abuses.

    • Five current or former Internal Revenue Service workers have been charged with fraud for illegally getting money from federal COVID-19 relief programs and using a total of $1 million for luxury items and personal trips, prosecutors said, the AP reported. The U.S. attorney’s office in Memphis said Tuesday that the five have been charged with wire fraud after they filed fake applications for the Paycheck Protection Program and the Economic Injury Disaster Loan Program, which were part of a federal stimulus package tied to the pandemic response in 2020.

    • Peloton Interactive Inc.
    PTON,
    +3.84%

    said it plans to cut about 500 jobs, roughly 12% of its remaining workforce, in the company’s fourth round of layoffs this year as the connected fitness-equipment maker tries to reverse mounting losses, the Wall Street Journal reported. After enjoying a strong run early on in the pandemic, Peloton has struggled since the start of the U.S. recovery, and CEO Barry McCarthy, who took over in February, said he is giving the unprofitable company another six months or so to significantly turn itself around and, if it fails, Peloton likely isn’t viable as a stand-alone company.

    Don’t missPeloton CEO says ‘naysayers’ are looking at the company’s $1.2 billion quarterly loss all wrong.

    Here’s what the numbers say:

    The global tally of confirmed cases of COVID-19 topped 619.9 million on Wednesday, while the death toll rose above 6.55 million, according to data aggregated by Johns Hopkins University.

    The U.S. leads the world with 96.6 million cases and 1,061,490 fatalities.

    The Centers for Disease Control and Prevention’s tracker shows that 225.3 million people living in the U.S., equal to 67.9% of the total population, are fully vaccinated, meaning they have had their primary shots. Just 109.9 million have had a booster, equal to 48.8% of the vaccinated population, and 23.9 million of those who are eligible for a second booster have had one, equal to 36.6% of those who received a first booster.

    Some 7.6 million people have had a shot of one of the new bivalent boosters that target the new omicron subvariants that have become dominant around the world.

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  • A strong fall COVID booster campaign could save 90,000 U.S. lives and avoid more than 936,000 hospitalizations, study finds

    A strong fall COVID booster campaign could save 90,000 U.S. lives and avoid more than 936,000 hospitalizations, study finds

    A strong fall COVID booster campaign could save about 90,000 people living in the U.S. from dying of the virus and avoid more than 936,000 hospitalizations, according to a new study by the Commonwealth Fund.

    As immunity wanes and new variants that can evade protection from early vaccines emerge, surges in hospitalizations and deaths are increasingly likely this fall and winter, the authors wrote. That makes it important that people get the bivalent boosters recently authorized by the Food and Drug Administration and help stop transmission, they wrote.

    Researchers analyzed three scenarios to evaluate the impact of vaccination on reducing fatalities, hospitalizations and medical costs to both the Medicare and Medicaid programs.

    The first measured the outcome if daily vaccination rates remain unchanged from current levels; they have gradually declined since the first wave of the omicron variant. Federal financial support has also not been replenished, amid a perception among many Americans that the pandemic is over and as congressional Republicans oppose legislative efforts to continue the pandemic fight.

    As of Oct. 3, some 68% of the U.S. population has had primary shots, but fewer than half of those have received a booster dose, and only 36% of those aged 50 and older have had a second booster.

    The second and third Commonwealth Fund scenarios looked at outcomes if rates increased by the end of 2022.

    In one scenario, researchers imagined booster uptake would track flu-shot coverage in 2020 to 2021. The other scenario assumed 80% of eligible individuals 5 and older get a booster by the end of 2022.


    Source: Commonwealth Fund

    The data found that more than 75,000 deaths could be prevented along with more than 745,000 hospitalizations if coverage reaches similar levels to 2021 to 2022 flu vaccination. The best scenario would save $56 billion in direct medical costs over the course of the next six months.

    “Stratifying by insurance type, we found direct medical costs would be reduced by $11 billion for Medicare alone under scenario 1 and $13 billion under scenario 2,” the authors wrote. “An additional $3.5 to $4.5 billion in savings would accrue to Medicaid. Even if the federal government paid all vaccination costs, accelerated campaigns would generate more than $10 billion in net savings from federal programs like Medicare and Medicaid.”

    The study comes as U.S. known cases of COVID are continuing to ease and now stand at their lowest level since late April, although the true tally is likely higher given how many people are testing at home, with data not being collected.

    The daily average for new cases stood at 44,484 on Tuesday, according to a New York Times tracker, down 22% from two weeks ago. Cases are rising in most northeastern states by 10% of more, while cases in the are rising in the western states Montana, Washington and Oregon.

    The daily average for hospitalizations was down 12% at 27,334, while the daily average for deaths is down 8% to 393. 

    The new bivalent vaccine might be the first step in developing annual Covid shots, which could follow a similar process to the one used to update flu vaccines every year. Here’s what that process looks like, and why applying it to Covid could be challenging. Illustration: Ryan Trefes

    Coronavirus Update: MarketWatch’s daily roundup has been curating and reporting all the latest developments every weekday since the coronavirus pandemic began

    Other COVID-19 news you should know about:

    • Long COVID, a condition that can encompass symptoms such as respiratory distress, cough, “brain fog,” fatigue and malaise that last 12 weeks or longer after initial infection, is becoming a long-term challenge as both employers and workers navigate an ever-mutating virus, according to Liz Seegert, writing for NextAvenue.org. The Centers for Disease Control and Prevention found that one in five COVID survivors younger than 65 experienced at least one incident that might be related to previous COVID-19 infection. Among those 65 and older, the rate was one in four. Their data also show that nearly three times as many people age 50 to 59 currently have long COVID than those 80 or older.

    • A retired judge opened a public inquiry on Tuesday into how Britain handled the coronavirus pandemic, saying bereaved families and those who suffered would be at the heart of the proceedings, the Associated Press reported. Former Court of Appeal judge Heather Hallett said the inquiry would investigate the U.K.’s preparedness for a pandemic, how the government responded, and whether the “level of loss was inevitable or whether things could have been done better.”

    With each mutation, the Covid-19 virus is becoming more transmissible. WSJ’s Daniela Hernandez breaks down the science of how Covid variants are getting better at infecting and spreading. Illustration: Rami Abukalam

    • Health experts are keeping an eye on new versions of the BA.5 omicron subvariant amid concerns those virus versions can evade the drugs developed to fight COVID, Salon reported. Of particular concern are two named BQ.1 and BQ.1.1, along with BA.2.75.2, which is spreading in Singapore, India and parts of Europe. Then there’s XBB, which some research suggest is the most antibody-evasive strain tested so far. The World Health Organization said in its weekly update on the virus that BA.5 descendent lineages continued to be dominant in the latest week, accounting for 80.8% of sequences shared through a global database. It also noted “increased diversity” within omicron and its lineages.

    • Eiger BioPharmaecuticals Inc.
    EIGR,
    -5.01%

    said Wednesday it will not pursue emergency authorization of its experimental treatment for mild and moderate COVID-19 infections. It had asked the Food and Drug Administration to consider an EUA application based on data from the Together trial, a Phase 3 study that has assessed 11 possible treatments for COVID-19 that is being conducted in Brazil and Canada. Eiger said the FDA instead recommended the company consider running its own pivotal trial for peginterferon lambda that would support full approval of the drug.

    Here’s what the numbers say:

    The global tally of confirmed cases of COVID-19 topped 619.2 million on Wednesday, while the death toll rose above 6.55 million, according to data aggregated by Johns Hopkins University.

    The U.S. leads the world with 96.5 million cases and 1,060,446 fatalities.

    The Centers for Disease Control and Prevention’s tracker shows that 225.3 million people living in the U.S., equal to 67.9% of the total population, are fully vaccinated, meaning they have had their primary shots. Just 109.9 million have had a booster, equal to 48.8% of the vaccinated population, and 23.9 million of those who are eligible for a second booster have had one, equal to 36.6% of those who received a first booster.

    Some 7.6 million people have had a shot of the new bivalent booster that targets the new omicron subvariants that have become dominant around the world.

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  • CDC scraps travel health notices as countries slow testing, and study confirms Republican-leaning counties suffered more COVID deaths than Democrat-leaning ones

    CDC scraps travel health notices as countries slow testing, and study confirms Republican-leaning counties suffered more COVID deaths than Democrat-leaning ones

    The U.S. Centers for Disease Control and Prevention has dropped its country-by-country COVID-19 travel health notices that it began issuing early in the pandemic, the Associated Press reported. 

    The reason: Fewer countries are testing for the virus or reporting the number of COVID cases. That limits the CDC’s ability to calculate travelers’ risk, according to the agency.

    CDC spokeswoman Kristen Nordlund said the agency will only post a travel health notice for an individual country if a situation such as a troubling new variant of the virus changes CDC travel recommendations for that country.

    The CDC still recommends that travelers remain up-to-date on vaccines and follow recommendations found on its international travel page.

    From the CDC: Stay Up to Date with COVID-19 Vaccines Including Boosters

    A new study from the National Bureau of Economic Research has confirmed that political affiliations played a key role as a risk factor for dying of COVID, finding evidence that Republican-leaning counties suffered higher death rates than Democratic-leaning ones.

    “We estimate substantially higher excess death rates for registered
    Republicans when compared to registered Democrats, with almost all of the difference concentrated in the period after vaccines were widely available in our study states,” the authors, Jacob Wallace and Jason L. Schwartz of the Yale School of Public Health, and Paul Goldsmith-Pinkham of the Yale School of Management wrote.

    “Overall, the excess death rate for Republicans was 5.4 percentage points (pp), or 76%, higher than the excess death rate for Democrats.”

    The researchers used data from Ohio and Florida and matched 2017 voter registration data with mortality data from 2018 to 2021. They also found a link between political affiliation and views on vaccines, with Republican-leaning counties showing far lower vaccination rates.


    Source: NBER paper

    In the U.S., known cases of COVID are continuing to ease and now stand at their lowest level since late April, although the true tally is likely higher given how many people are testing at home, where the data are not being collected.

    The daily average for new cases stood at 45,495 on Monday, according to a New York Times tracker, down 24% from two weeks ago. Cases are rising in 11 states plus Washington, D.C. They are up by double-digit percentages in Rhode Island, Massachusetts and Vermont.

    The daily average for hospitalizations was down 11% at 27,854, while the daily average for deaths is down 12% to 386. 

    Coronavirus Update: MarketWatch’s daily roundup has been curating and reporting all the latest developments every weekday since the coronavirus pandemic began

    Other COVID-19 news you should know about:

    • Norwegian Cruise Line Holdings Ltd.
    NCLH,
    +16.84%

    is removing all COVID testing, vaccination and masking requirements from its health and safety protocols. The company said the new protocols, which follows “significant, positive progress” in the public health environment, will be effective Oct. 4. “Health and safety are always our first priority; in fact, we were the health and safety leaders from the very start of the pandemic,” said Chief Executive Harry Sommer. “Many travelers have been patiently waiting to take their long-awaited vacation at sea and we cannot wait to celebrate their return.” 

    See also: Would you take a cruise without such COVID-19 testing, vaccination and masks? MarketWatch asked health experts to weigh in.

    • Ringo Starr has test positive for COVID, forcing the former Beatle to cancel scheduled concerts in Canada with his All Starr Band, the AP reported. Five concert dates from Tuesday to Sunday — in Winnipeg, Manitoba; Saskatoon, Saskatchewan; Lethbridge, Alberta; and the British Columbia cities of Abbotsford and Penticton — will be rescheduled. “Ringo hopes to resume as soon as possible and is recovering at home. As always, he and the All Starrs send peace and love to their fans and hope to see them back out on the road soon,” said a statement from the band.

    The new bivalent vaccine might be the first step in developing annual Covid shots, which could follow a similar process to the one used to update flu vaccines every year. Here’s what that process looks like, and why applying it to Covid could be challenging. Illustration: Ryan Trefes

    • A federal appeals court in New Orleans on Monday became the latest to hear arguments on whether President Joe Biden overstepped his authority with an order that federal contractors require that their employees be vaccinated against COVID, the AP reported separately. The contractor mandate has a complicated legal history. It is being challenged in more than a dozen federal court districts, and the mandate has been blocked or partially blocked in 25 states. 

    • The Chinese resort city of Sanya has ordered all tourists to take PCR tests, and those who fail to do so by noon on Tuesday will be slapped with a yellow code restricting their mobility, according to local officials, the South China Morning Post reported. The city in the southern province of Hainan logged two asymptomatic Covid-19 cases on Monday. It carried out a round of mass testing and locked down several areas in Haitang district, including a scenic island that received around 2,000 tourists on Monday.

    Here’s what the numbers say:

    The global tally of confirmed cases of COVID-19 topped 618.7 million on Tuesday, while the death toll rose above 6.54 million, according to data aggregated by Johns Hopkins University.

    The U.S. leads the world with 96.4 million cases and 1,059,888 fatalities.

    The Centers for Disease Control and Prevention’s tracker shows that 225.3 million people living in the U.S., equal to 67.9% of the total population, are fully vaccinated, meaning they have had their primary shots. Just 109.9 million have had a booster, equal to 48.8% of the vaccinated population, and 23.9 million of those who are eligible for a second booster have had one, equal to 36.6% of those who received a first booster.

    Some 7.6 million people have had a shot of the new bivalent booster that targets the new omicron subvariants that have become dominant around the world.

     

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  • 1 in 5 of Americans don’t know about new omicron-targeting COVID boosters, survey finds

    1 in 5 of Americans don’t know about new omicron-targeting COVID boosters, survey finds

    About half of the American public has heard little or nothing about the new COVID-19 bivalent booster, a new survey by the Kaiser Family Foundation has found. The new booster targets the omicron variants that have become dominant around the world.

    One in five of those surveyed said they had heard “nothing at all” about the new boosters. Some 17% said they had heard “a lot” about the boosters, while 33% said they had heard “some” about the new shots. About a third said they’d already gotten the new booster or intended to do so as soon as possible.

    “Intention is somewhat higher among older adults, one of the groups most at risk for serious complications of a coronavirus infection,” the authors wrote. “Almost half (45%) of adults ages 65 and older say they have gotten the bivalent booster or intend to get it ‘as soon as possible.’”


    Source: Kaiser Family Foundation

    The news will likely disappoint health experts who cheered the regulatory authorization of the new boosters in August. The U.S. Food and Drug Administration granted emergency-use authorization to boosters developed by Moderna
    MRNA,
    +1.36%

    and by Pfizer
    PFE,
    -0.07%

    and German partner BioNTech
    BNTX,
    +1.53%

    for use in people aged 12 and older who have had an initial series of a COVID vaccine, including those who have already had one or more booster doses.

    The Centers for Disease Control and Prevention is recommending that all adults get one of the bivalent boosters at least two months after completing a primary series of shots. So far, some 7.6 million people in the U.S. have received it, according to the CDC.

    From the CDC: Stay Up to Date with COVID-19 Vaccines Including Boosters

    Once again, the country’s partisan divide is evident, with 6 in 10 Democrats saying they’ve already had the shot or will get it soon, compared with 1 in 8 Republicans.

    “Notably, 20% of Republicans say they will ‘definitely not’ get the new COVID-19 booster dose, while a further 38% of Republicans are unvaccinated or only partially vaccinated and therefore not eligible for the new updated COVID-19 booster dose,” the survey authors said.

    Also read: A common virus is putting more children in the hospital than in recent years

    In the U.S., known cases of COVID are continuing to ease and now stand at their lowest level since late April, although the true tally is likely higher given how many people are testing at home, where data are not being collected.

    The daily average for new cases stood at 47,569 on Thursday, according to a New York Times tracker, down 26% from two weeks ago and now at the lowest level since late April. Cases are rising in 14 states and are sharply higher in several. Montana leads the count with a 75% rise in the last two weeks, followed by Washington with a 48% rise. Cases are up by double digits in Rhode Island, New York, Massachusetts, New Hampshire, Vermont and New Jersey.

    The daily average for hospitalizations was down 13% to 28,639, while the daily average for deaths was down 11% to 407.

    The new bivalent vaccine might be the first step in developing annual COVID shots, which could follow a similar process to the one used to update flu vaccines every year. Here’s what that process looks like, and why applying it to COVID could be challenging. Illustration: Ryan Trefes

    Coronavirus Update: MarketWatch’s daily roundup has been curating and reporting all the latest developments every weekday since the coronavirus pandemic began

    Other COVID-19 news you should know about:

    • The U.K. is the only G-7 country whose economy is smaller now than before the pandemic, the Guardian reported, citing data released Friday by the Office for National Statistics. The ONS released figures showing that rather than the economy being 0.6% larger than it was in February 2020, a combination of a deeper recession during the pandemic and a weak recovery had left it 0.2% smaller. All the other major economies in the G-7, including France and Italy, recovered strongly enough to be larger than they were in February 2020.

    • Taiwan is the latest country to end mandatory COVID quarantines for people arriving from overseas, the Associated Press reported. Officials said that beginning Oct. 13, the previous weeklong quarantine requirement would be replaced with a seven-day self-monitoring period. A rapid antigen test will still be required upon arrival, but people showing no symptoms will be allowed to take public transportation. 

    • Germany’s health ministry is warning of a rise of COVID cases heading into the fall and is urging older people in particular to get a second booster shot, the AP reported separately. Other European countries such as France, Denmark and the Netherlands are also recording an increase in cases, German Health Minister Karl Lauterbach told reporters in Berlin. “We are clearly at the start of a winter wave,” he said.

    COVID-19 lockdowns, corruption crackdowns and more have put China’s economy on a potential crash course with the U.S. and the rest of the world, the Wall Street Journal’s Dion Rabouin explains. Illustration: David Fang

    • The first Chinese mRNA-based COVID vaccine has received government approval — in Indonesia, the New York Times reported. The shot, developed by Walvax Biotechnology
    300142,
    +0.49%
    ,
    Suzhou Abogen Biosciences and the Chinese military, was cleared this week by Indonesia for emergency use. Countries all over the world, including Indonesia, have embraced mRNA vaccines, and they are considered among the most effective vaccines that the world has to offer. But more than two years into the pandemic, they are not yet available in China, which has relied on an increasingly draconian “zero-COVID” approach to keep cases and deaths from the virus low.

    • Patriarch Kirill of Moscow, the head of the Russian Orthodox Church and a supporter of Russia’s war on Ukraine, has tested positive for COVID-19, the church’s press service said on Friday, Reuters reported. The church said Kirill, 75, a close ally of Russian President Vladimir Putin, had canceled all his planned trips and events and had “severe symptoms” requiring bed rest and isolation. It said his condition was “satisfactory.”

    Here’s what the numbers say:

    The global tally of confirmed cases of COVID-19 topped 617.3 million on Friday, while the death toll rose above 6.54 million, according to data aggregated by Johns Hopkins University.

    The U.S. leads the world with 96.3 million cases and 1,059,291 fatalities.

    The Centers for Disease Control and Prevention’s tracker shows that 225.3 million people living in the U.S., equal to 67.9% of the total population, are fully vaccinated, meaning they have had their primary shots. Just 109.9 million have had a booster, equal to 48.8% of the vaccinated population, and 23.9 million of those who are eligible for a second booster have had one, equal to 36.6% of those who received a first booster.

     

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