ReportWire

Tag: Michigan Medicine – University of Michigan

  • Few older adults use direct-to-consumer health services; many who do don’t tell their regular provider

    Few older adults use direct-to-consumer health services; many who do don’t tell their regular provider

    [ad_1]

    Newswise — Only a small percentage of older Americans have jumped on the rising trend of getting health care services and prescriptions directly from an online-only company, rather than seeing their usual health care providers in person or via telehealth, a new poll finds.

    But that could change rapidly, the University of Michigan survey suggests.

    In all, 7.5% of people between the ages of 50 and 80 have used at least one direct-to-consumer health care service from an online-only provider, according to the new findings from the National Poll on Healthy Aging.

    Of those who did use such a service, most said they were driven by convenience. More than 60% of them received a prescription, mostly for a one-time treatment. But only one-third of them told their regular health care provider about the prescription.

    People in their pre-Medicare years of 50 to 64 were more than twice as likely as adults over 65 to have used direct-to-consumer, or DTC, online health services (10% vs. 4%). Meanwhile, 47% of those over 65 said they had never heard of such companies.

    Looking to the future, nearly a third of all older adults, and more than 42% of those age 50 to 64, said they’d be interested in using such services in the future.

    The poll is based at the U-M Institute for Healthcare Policy and Innovation, and supported by AARP and Michigan Medicine, U-M’s academic medical center.

    For the DTC survey, the poll team worked with members of U-M’s Center for Value-Based Insurance Design, who are interested in how cost and convenience influence people’s health care decisions and the continuity of care delivery.

    A rapidly growing sector spurs concerns

    The rise of DTC sites and subscription-based apps that promise convenient online access to providers who can evaluate symptoms, make diagnoses and prescribe medicines has received a lot of attention, especially amid a national crunch in availability of primary care providers and timely appointments.

    Such companies include Amazon Clinic, Sesame, Roman, BetterHelp, Rosy, Lemonaid, Hims & Hers, and don’t require a referral or health insurance. Drug companies and membership-based organizations including Weight Watchers and Costco have also started offering access to such direct services.

    But the trend has raised concern because of the potential for patients to receive care and prescriptions from providers who don’t know their full health history, don’t have access to their full medical records, and may not check for potentially dangerous interactions between medications.

    One-third of those who had used a DTC service said their primary care provider wasn’t aware they had done so. If they received a new prescription through an encounter with a DTC health service, one-third said their regular primary care provider was not made aware of the new medication they were prescribed. The majority of those who received prescriptions through a DTC service said it was for a one-time treatment.

    “These compelling findings have important implications for patient safety and continuity of care,” said Mark Fendrick, M.D., director of VBID and IHPI member who is a primary care physician at Michigan Medicine. “With rapid growth in this sector of health care predicted for this year and beyond, all providers, insurers and regulators need to pay more attention to how patients are using these services and why, and the impact on care quality and safety.” Fendrick is a professor of internal medicine in the Division of General Medicine at the U-M Medical School.

    His colleague Nicole Hadeed, M.D., who also worked on the poll and is a clinical assistant professor, notes that while the number of poll participants who said they had used DTC services was relatively small, the analysis gives clues that should inform further research.

    Types of care received

    Nearly half of those who had used a DTC service said it has been for general health care such as treatment of allergies, sinus infections, pink eye or acid reflux, though again there was a clear divide between the 50-64 and 65-80 age groups.

    Overall, nearly 12% said they’d used a service for mental health reasons, but the proportion was much higher (50%) among respondents who said they considered their mental health to be fair or poor and had used a DTC service of any kind.

    As for other types of care, 15% had sought help from a DTC service for a sexual health issue, 9% had used it for skin care, 6% had used it for weight management, nearly 5% had used it for hair loss and a similar percentage had used it for pain management.

    Convenience topped the list of reasons for choosing a DTC service, with 55% saying this drove their decision. But lack of access to their regular health care provider, not having a regular health care provider, or needing a service when their health provider was not open or available were each cited by around 20%. Discomfort discussing a sensitive health topic with a provider – often cited in marketing by such companies – was only mentioned by 10% of those who had turned to a DTC service.

    “For both patients and providers, these findings drive home the importance of open dialogue and transparency about the potential uses, benefits and risks of these services – and the importance of maintaining contact for ongoing primary care,” said Jeffrey Kullgren, M.D., M.P.H., M.S., director of the poll and a primary care provider at the VA Ann Arbor Healthcare System who is also an associate professor at the Medical School.

    More than 55% of the poll respondents who had used a direct-to-consumer service said the overall quality of care they get from their primary care provider is better than what they received from a DTC provider.

    Fendrick and Hadeed wrote about the potential long-term change to primary care use from telehealth services in a piece published early in the COVID-19 pandemic in the American Journal of Managed Care.

    And in fact, 58% of poll respondents who had used a DTC service had started doing so in 2020, 2021 or 2022.

    The rapid pivot during the pandemic to vaccination in pharmacies, and not just primary care clinics, has also changed how people think about alternate ways of getting care that might be closer to home or have more flexible hours.

    However, Fendrick notes, pharmacies share information about vaccination with insurance companies and statewide immunization registries that primary care providers can access.

    “Patients will increasingly seek care online because of the convenience it can provide, especially for those willing to pay the cost out of pocket,” said Fendrick. “Its use will likely be boosted by the rapidly increasing number of online vendors and the national shortage of primary care clinicians. The recent launch of a telemedicine platform offering home delivery for the new highly popular weight loss drugs is a noteworthy example of this trend.”

    He added, “Given a likely expansion of online care, it is critical that individuals inform their usual clinician and that we providers consistently ask our patients regarding their use. Similar to my routinely asking patients about which supplements, vitamins and over-the-counter medications they’re taking, it should become standard practice for me to inquire about prescriptions or diagnoses they’ve received online, as it might influence their care.”

    The poll was a nationally representative survey conducted by NORC at the University of Chicago for IHPI and administered online and via phone in July and August 2023 among 2,657 adults aged 50 to 80. In all, 168 respondents reported having used a DTC health care service. The sample was subsequently weighted to reflect the U.S. population. Read past National Poll on Healthy Aging reports and about the poll methodology.

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • 1 in 8 older adults use cannabis products, suggesting need to screen for risks

    1 in 8 older adults use cannabis products, suggesting need to screen for risks

    [ad_1]

    Newswise — More older Americans use cannabis now than before the pandemic, with 12% saying they’ve consumed a THC-containing substance in the past year and 4% saying they do so multiple times a week, according to a new study of people aged 50 to 80. Those who drink alcohol at risky levels have a much higher rate of cannabis use.

    The new findings, published in the journal Cannabis and Cannabinoids Research by a team from the University of Michigan’s Institute for Healthcare Policy and Innovation, suggest a need for more education and screening of older adults for cannabis-related risks.

    “As the stress of the pandemic and the increased legalization of cannabis by states converged, our findings suggest cannabis use increased among older adults nationally. Older adults represent a vulnerable age group for cannabis use due to interactions with medications, risky driving, cannabis-related mental health impacts and increased possibility of falls and memory issues,” said Anne Fernandez, Ph.D., an addiction psychologist in the U-M Addiction Center and Department of Psychiatry who led the study.

    The data in the study come from the National Poll on Healthy Aging, which IHPI runs with funding from AARP and Michigan Medicine, U-M’s academic medical center. The national poll of 2,023 older adults was taken in January 2021, nine months into the official pandemic declaration and just as the first COVID-19 vaccines were being made available to the groups at the highest risk.

    The 12% overall past-year use of cannabis seen in the new study is higher than the 9.5% seen in 2019 by other researchers pre-pandemic, and far higher than the 3% seen in another study in 2006, when only 12 states had passed medical cannabis laws. The NPHA in 2017 found that 6% of older adults had used cannabis for medical purposes.

    In the new study, in addition to the 4% who said they use cannabis products four or more times a week, another 5% said they use cannabis once a month or less. The poll question asked about use of any product containing THC, the main psychoactive component of cannabis — including edibles – and used multiple common names for cannabis. It did not differentiate between medical and recreational use of cannabis.

    Older adults who said they were unemployed, those who said they were unmarried and had no partner, and those who said they drank alcohol were more likely to say they used cannabis.

    Fernandez notes an especially concerning finding: those whose alcohol use was high enough to cause physical and psychological harms were nearly eight times as likely to say they had used cannabis in the past year. But even those with low-risk alcohol drinking patterns were more than twice as likely to say they had used cannabis in the past year.

    This group of dual-substance users is one that doctors and public health officials should pay special attention to, she said.

    “Other research has shown that using both alcohol and cannabis increases the chance that a person will drive while impaired,” she explained. “They are also more likely to have physical and mental health issues, including substance use disorders. Screening for alcohol use, cannabis use, and other drug use could help more people get counseling and reduce their risk and risk to others.”

    While there were no statistical differences among older adults by age, health or mental health status, income or education, those who said they had Hispanic backgrounds were less likely than non-Hispanic older adults to say they used cannabis. Fernandez says this is consistent with other research showing lower cannabis use in the Latino community.

    She advises any older adult who chooses to use cannabis products for any reason to be open with their health care provider about it, especially if they also drink alcohol or take certain medications. Physicians, nurse practitioners and pharmacists can advise if any medications a person is taking might interact with cannabis, including ones for insomnia, depression and anxiety, opioid-containing pain medications, seizure medications, and blood thinners.

    For more about the poll methodology, see https://www.healthyagingpoll.org/survey-methods

    In addition to Fernandez, the study’s authors are U-M addiction psychologist Lara Coughlin, Ph.D., poll deputy director Erica S. Solway, Ph.D., poll manager Dianne C. Singer, poll director Jeffrey T. Kullgren, M.D., M.S., M.P.H., poll data lead Matthias Kirch, M.S. and Preeti N. Malani, M.D., former poll director and current poll senior advisor.

     

    In addition to the poll funding, Fernandez has research funding from the National Institute of Alcohol Abuse and Alcoholism (AA023869).

    Prevalence and Frequency of Cannabis Use Among Adults Ages 50–80 in the United States, Cannabis and Cannabinoid Research, DOI: 10.1089/can.2023.0056 https://doi-org.proxy.lib.umich.edu/10.1089/can.2023.0056

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • Different pain types in multiple sclerosis can cause difficulty staying active

    Different pain types in multiple sclerosis can cause difficulty staying active

    [ad_1]

    BYLINE: Valerie Goodwin

    Newswise — For patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes of chronic pain, physical exercise can be more difficult for some.

    Research published in the Journal of Pain from the University of Michigan found that widespread pain with nociplastic features can make engaging in physical activity a painful task for patients with MS.

    “Widespread pain with nociplastic features is a chronic and diffuse pain which can be challenging to localize or describe precisely,” said Libak Abou, Ph.D., research assistant professor and lead author of the paper. 

    “In a person with MS, this type of pain arises from altered processing signals within the central nervous system. This is opposed to pain that arises from specific tissue damage, classified as nociceptive pain, or pain related to demyelination and axonal damage, classified as neuropathic pain.”

    Abou and fellow researchers surveyed patients with MS to see if those with a higher indication of widespread pain with nociplastic features were more likely to be insufficiently active or sedentary when compared to their MS counterparts with no chronic pain, nociceptive pain, or neuropathic pain.

    Each of the participants was self-reporting with their data.

    The results of the survey showed that those who experienced WPNF in addition to their MS were not sufficiently active due to the chronic pain they were experiencing.

    “There is a growing need to consider what type of pain MS patients are experiencing before giving them an exercise plan,” said Abou.

    “The concept of considering widespread pain with nociplastic features when creating exercise plans for MS is newer but could help many patients get to an activity level that will help ease symptoms without causing them intense pain.”

    For the future, Abou hopes that clinicians can begin doing screenings for underlying pain mechanisms in patients with MS that are struggling to stay active to help further tailor their physical routines to their personal needs.

    “The end goal is to help those with MS maintain their functional independence,” said Abou.

    “It is also important to remember that these patients will likely need extra support from their physical therapy team to keep them on a path with less pain.”

    Additional authors: Libak Abou, Daniel Whibley, and Anna L. Kratz from the Department of Physical Medicine and Rehabilitation, Michigan Medicine, University of Michigan, Ann Arbor, Michigan as well as the Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, Michigan. Daniel J. Clauw from the Department of Anesthesiology, Michigan Medicine, University of Michigan, Ann Arbor, Michigan.

    Paper cited: “Widespread Pain With Nociplastic Features is an Independent Predictor of Low Physical Activity in People with Multiple Sclerosis,” The Journal of Pain. DOI: 10.1016/j.jpain.2023.09.005

     

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • Older adults from distressed communities attend less cardiac rehab after heart procedures

    Older adults from distressed communities attend less cardiac rehab after heart procedures

    [ad_1]

    BYLINE: Noah Fromson

    Newswise — Older adults who live in disadvantaged communities are less likely to attend cardiac rehabilitation after common heart procedures, a Michigan Medicine-led study finds.

    The study aimed to calculate how many Medicare beneficiaries attended cardiac rehabilitation, a medically supervised program exercise and education program, after coronary revascularization between mid-2016 and 2018.

    Patient communities were categorized using the Distressed Community Index, which analyzes economic well-being and social determinants of health, such as educational disparities and poverty rate, of United States zip codes.

    Only 26% of patients from distressed communities use cardiac rehab, compared to 46% of patients from areas deemed prosperous. Any patient who attended cardiac rehab, no matter where they lived, had a reduced risk of death, hospitalization and heart attack, according to results published in Circulation: Cardiovascular Quality and Outcomes.

    “Addressing barriers to participation in cardiac rehabilitation in distressed communities may improve outcomes for these patients and reduce longstanding disparities in such outcomes,” said first author Michael P. Thompson, Ph.D., assistant professor of cardiac surgery at University of Michigan Medical School.

    “While some individuals who face geographic barriers to participation may benefit from transportation services or virtual options for cardiac rehab, there is a critical need to address socioeconomic barriers that prevent so many patients from attending this lifesaving therapy.”

    Additional authors include, Hechuan Hou, Francis D. Pagani, M.D., Ph.D., Robert B. Hawkins, M.D., Devraj Sukul, M.D., and Donald S. Likosky, Ph.D., all of University of Michigan, James W. Stewart II, M.D., of Yale School of Medicine, and Steven J. Keteyian, Ph.D., of Henry Ford Health.

    This study was funded as part of a career development award Thompson received from the Agency for Healthcare Research and Quality (AHRQ, Grant no. 1K01HS027830).

    Paper cited: “Relationship Between Community-Level Distress and Cardiac Rehabilitation Participation, Facility Access, and Clinical Outcomes After Inpatient Coronary Revascularization,” Circulation: Cardiovascular Quality and OutcomesDOI: 10.1161/CIRCOUTCOMES.123.010148

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • Potato starch supplements could be solution to bone marrow transplant complications

    Potato starch supplements could be solution to bone marrow transplant complications

    [ad_1]

    BYLINE: Tessa Roy

    Newswise — Experts at the University of Michigan Health Rogel Cancer Center have found a potential solution for preventing a common and dangerous complication in patients that receive stem cell transplants from a donor’s blood or bone marrow.  

    Approximately 18,000 people per year in the United States are diagnosed with life threatening illnesses, including blood cancers where a blood or bone marrow stem cell transplant from a donor is their best treatment option.

    About 9,000 such transplants are performed yearly in the U.S. 

    When patients receive a stem cell transplant, they get a new immune system from the donor whose job is to attack cells that don’t belong there including cancer cells. 

    Sometimes, however, those donor immune cells (the graft) begin to see the patient’s own body (the host) as unfamiliar and foreign. As a result, the donor cells may attack the patient’s own organs and tissues, causing Graft versus Host Disease. 

    GVHD develops in up to half of patients who receive stem cell transplants from a donor’s blood or bone marrow. It can affect many parts of the body and can range from mild or moderate to more severe and even life threatening.

    The way to prevent and treat GVHD is by using strong medicines to suppress the immune system which can cause patients to get infections which can also be life-threatening. Therefore, while bone marrow and blood stem cell transplants from a donor are lifesaving for many patients with various serious illnesses, the development of GVHD can cause injury or even death and the treatments available for GVHD are risky.  

    Previous research showed that the bacteria that normally live in the intestines and their products can affect whether or not GVHD happens after a transplant. 

    Researchers have found that a food supplement made from potato starch, when given to ten patients who received stem cell transplants from a donor, changed the products of intestinal bacteria in a way that could potentially prevent GVHD from happening.   

    “GVHD is a major limitation to the lifesaving capability of blood or marrow stem cell transplants. It is exciting to think of the prospect of potentially finding a simple, low-cost, and safe approach to mitigating this dangerous complication for patients who need a stem cell transplant, but researching this approach in more patients is still needed to confirm,” said Mary Riwes, D.O., assistant professor of internal medicine and medical director of the inpatient adult stem cell transplant unit of the Medical Directors Partnering to Lead Along with Nurse Managers program.   

    Investigators are currently enrolling more patients for a second phase of this study to determine whether taking potato starch will indeed result in less GVHD after stem cell transplant. Sixty patients undergoing a blood or bone marrow stem cell transplant from a donor who are ten years or older will be randomized to take potato starch or placebo starch in addition to taking all the usual medications for preventing GVHD with 80% receiving potato starch and 20% placebo starch. This phase II clinical trial will help researchers learn whether or not taking potato starch is an effective intervention for preventing GVHD. 

    More information about this Phase II trial can be found on Clinicaltrials.gov identifier: NCT02763033 

    Additional authors include Jonathan L. Golob, John Magenau, Mengrou Shan, Gregory Dick, Thomas Braun, Thomas M. Schmidt, Attaphol Pawarode, Sarah Anand, Monalisa Ghosh, John Maciejewski, Darren King, Sung Choi, Gregory Yanik, Marcus Geer, Ethan Hillman, Costas A. Lyssiotis, Muneesh Tewari and Pavan Reddy

    Funding/disclosures: Thanks to the volunteers who participated in the study and the clinical and research staff of the University of Michigan Bone Marrow Transplant program. This work was supported by the National Heart, Lung, and Blood Institute (grant no. P01 HL149633, P.R., M.T., M.M.R.) which facilitated all bio sample analyses. The funder had no role in the design and analysis of the study. Resistant starch was purchased using institutional startup funds (M.M.R). 

    Paper cited: “Feasibility of a dietary intervention to modify gut microbial metabolism in patients with hematopoietic stem cell transplantation,” Nature. DOI: 10.1038/s41591-023-02587-y

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • Michigan Medicine Expert: Aaron Rodgers Achilles Tendon Rupture

    Michigan Medicine Expert: Aaron Rodgers Achilles Tendon Rupture

    [ad_1]

    BYLINE: Valerie Goodwin

    During Aaron Rodger’s debut as a New York Jet on Monday night, he experienced an achilles tendon rupture early into the game that resulted in Rodgers not returning to the field. The University of Michigan Health System’s David Walton, M.D., has commented on what this means in terms of treatment and repair from a medical standpoint.

    “An achilles tendon rupture is a tear of the tendon that connects the calf muscle to the foot. It’s the main driver for push off strength during walking and running,” said Walton.

    “For the athletic population, this is typically treated with a surgical repair and extended rehab. This often takes one year to return to play and up to two years for full recovery.”

    David M. Walton, M.D. is an Assistant Professor of Orthopaedic Surgery at the University of Michigan specializing in disorders of the Foot and Ankle. Walton is open to media inquires for further information about this type of injury and treatment.

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • AI can predict certain forms of esophageal and stomach cancer

    AI can predict certain forms of esophageal and stomach cancer

    [ad_1]

    BYLINE: Jina Sawani, Michigan Medicine

    Newswise — In the United States and other western countries, a form of esophageal and stomach cancer has risen dramatically over the last five decades. Rates of esophageal adenocarcinoma, or EAC, and gastric cardia adenocarcinoma, or GCA, are both highly fatal.

    However, Joel Rubenstein, M.D., M.S., a research scientist at the Lieutenant Colonel Charles S. Kettles Veterans Affairs Center for Clinical Management Research and professor of internal medicine at Michigan Medicine, says that preventative measures can be a saving grace.

    “Screening can identify pre-cancerous changes in patients, Barrett’s esophagus, which is sometimes diagnosed in individuals who have long-term gastroesophageal reflux disease, or GERD,” he said.

    “When early detection occurs, patients can take additional steps to help prevent cancer.”

    While current guidelines already consider screening in high-risk patients, Rubenstein notes that many providers are still unfamiliar with this recommendation.

    “Many individuals who develop these types of cancer never had screening to begin with,” he said.

    “But a new automated tool embedded in the electronic health record holds the potential to bridge the gap between provider awareness and patients who are at an increased risk of developing esophageal adenocarcinoma and gastric cardia adenocarcinoma.”

    Rubenstein and a team of researchers used a type of artificial intelligence to examine data regarding EAC and GCA rates in over 10 million U.S. veterans.

    Their findings were published in Gastroenterology

    Rubenstein and his team developed and tested the Kettles Esophageal and Cardia Adenocarcinoma predictioN tool, called K-ECAN for short.

    “K-ECAN uses basic information already readily available in the EHR, like patient demographics, weight, previous diagnoses and routine laboratory results, to determine an individual’s risk of developing esophageal adenocarcinoma and gastric cardia adenocarcinoma,” said Rubenstein.

    “We developed a prior tool, M-BERET, over a decade ago for identifying patients with Barrett’s esophagus. However, that tool requires measuring patients’ hip and waist circumferences, which is not something that routinely occurs. In addition, providers must remember to use the corresponding website to calculate their patient’s risk when using this tool.”

    To alleviate this burden, Rubenstein said that they “envisioned harnessing the large amount of data already present in the EHR, as well as presenting their patients’ risk to their providers at opportune times,” such as when an individual is due for a colorectal screening or refilling an acid reducing prescription medication.

    According to Rubenstein, K-ECAN is more accurate than published guidelines or previously validated prediction tools and can “accurately predict cancer at least three years prior to a diagnosis.”

    “Symptoms of GERD, like heartburn, are an important risk factor for esophageal adenocarcinoma,” he said.

    “But most people with GERD symptoms will never develop esophageal adenocarcinoma and gastric cardia adenocarcinoma. In addition, roughly half of the patients with this form of cancer never experienced prior GERD symptoms at all. This makes K-ECAN particularly useful because it can identify people who are at elevated risk, regardless of whether they have GERD symptoms or not.”

    Akbar Waljee, M.D., M.Sc., professor in the Departments of Learning Health Sciences and Internal Medicine and senior author on the study, adds that this research wouldn’t be possible without a collaborative effort.

    “This publication, which leveraged invaluable data from millions of U.S. veterans, was made possible through the dedicated efforts of numerous staff members at our VA Health Services Research & Development Center of Innovation, as well as through collaborative partnerships between the VA Center for Clinical Management Research, Michigan Medicine, the University of Michigan Department of Statistics, and members of U-M’s Institute for Healthcare Policy & Innovation and E-Health & Artificial Intelligence, or e-HAIL. This exemplifies the power of team science, data and machine learning to improve cancer prevention.”

    Incorporating this artificial intelligence tool into the EHR could alert providers with an automated notification regarding which patients are at an increased risk of developing esophageal adenocarcinoma and gastric cardia adenocarcinoma.

    And Rubenstein says that this can significantly decrease the burden of these cancers

    “Our devoted team was able to use sophisticated machine learning tools to develop this unique tool, and we are very excited that this could potentially lead to increased screening and a decrease in preventable deaths. We look forward to conducting additional work validating K-ECAN for use outside of the VA.”

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • Remote learning during pandemic aids medical students with disabilities

    Remote learning during pandemic aids medical students with disabilities

    [ad_1]

    BYLINE: Patricia DeLacey

    Newswise — Medical students who reported a disability to their school increased by more than 25% during the COVID-19 pandemic, a study shows.

    The proportion of students reporting attention deficit hyperactivity disorder or chronic health and/or psychological disabilities has increased between 2015 and 2021.

    Despite the increase in medical students reporting these conditions, the requests for more inclusive preclinical testing accommodations, like extra time for test completion or a less distracting environment, decreased during the pandemic between 2019 and 2021.

    According to authors of the new research letter in JAMA Network Open, the remote curriculum delivery during the pandemic may have allowed students to create an optimal learning and testing environment, decreasing the need for accommodation.

    “Medical education was at its most flexible during COVID,” said Lisa Meeks, Ph.D., clinical associate professor of learning health sciences and family medicine at the University of Michigan Medical School.

    She adds that this could have reduced the need for testing accommodations, but it is unclear whether the need for accommodations will rise again after the recent return to in-person lectures and testing.

    Documenting the rise

    The study results are part of a long-term research project led by Meeks that follows the prevalence of medical students in the United States who disclose disabilities to their respective schools.

    This study on disability disclosure in medicine was the first large scale study of its kind, encompassing all types of disability, including psychological, learning, sensory, physical and chronic health conditions.

    Since 2015, researchers have seen an increase of medical students reporting a disability to their institution from 2.8% in 2015 to 4.7% in 2019, and to 5.9% in 2021.

    When asked to describe why we see such large increases in the population of medical students with disabilities, Meeks posited that “growth in this population could mean that we are reducing bias and stigma, and therefore people who were already in medicine are more willing to disclose.”

    “It could also mean that our research sparked a conversation to change policies, which then led to individuals with disabilities who didn’t think they could make it in medical school choosing to apply to these schools.”

    Doctors with disabilities improve patient care

    According to Meeks, there is still significant work to be done to increase the representation of doctors with disabilities in medicine.

    Only 5.9% of medical school students report a disability, but 27% of adults in the U.S. currently live with some type of disability.

    As the population ages, this number is expected to increase.

    “Physicians in the U.S. and many other countries report that they do not feel confident in their ability to provide equal quality of care to patients with disabilities as they provide to patients without disabilities,” said Karina Pereira-Lima, Ph.D., a research fellow in the Michigan Medicine neurology department.

    “The inclusion of professionals with disabilities in medicine can greatly improve the care for patients with disabilities and the health of the population overall.”

    Retaining medical trainees with disabilities

    Increasing the number of physicians with disabilities requires both the recruitment and retention of medical trainees.

    “Anonymous research with medical trainees with disability shows that about one in every five medical students and more than half of resident physicians do not request accommodations when they need them,” said Pereira-Lima.

    The two main reasons for not requesting needed accommodation were fear of stigma or bias and lack of a clear institutional process.

    “Program access, or simply having the ability to access accommodations should they need them, improves medical trainees with disabilities performance in relation to testing and patient care. It also reduces the likelihood of reporting depressive symptoms or burnout,” added Pereira-Lima.

    Meeks advocated for “standardization in support for students with disabilities in medical education.”

    “Medical education strives for parity and continuity between medical schools, but when it comes to disability services and reasonable accommodations, there’s no standardization whatsoever,” said Meeks.

    “One school could have an incredible specialized disability support services with a qualified disability resource professional running the office, while another school does not have a specialized disability support service at all.”

    ‘A wave of change’

    The team notes that addressing the second common barrier to attaining needed disability accommodations and fear of stigma or bias requires a continued culture shift in medicine.

    “Disability is still incredibly stigmatized, and ableism is rampant in medicine and medical education. At the same time, I think the work from our lab, the Association of American Medical Colleges, the Accreditation Council for Graduate Medical Education and others in medicine started a wave of change that is extraordinarily strong,” said Meeks.

    This work is bolstered by the matriculation of individuals that Meeks calls the post Americans with Disabilities Act generation into medical school.

    “This generation has a lot of disability pride. They’ve had accommodations their entire lives, they know the law, they know their rights and they’re not ashamed of being disabled,” said Meeks.

    Next steps

    As this long term study continues, the research team plans to assess how other identities interact with the disability identity.

    “People with disabilities have different racial and ethnic backgrounds, sexual orientations and socio-economic statuses. We want to learn more about how the interaction between these different identities impacts the performance and mental health of medical students with disabilities,” said Pereira-Lima. 

    Meeks adds that thanks to new funding from the Robert Wood Johnson Foundation the DocsWithDisabilities team is doing just that.

    “We’re also developing methods to measure the efficacy of accommodations. We need to do more research on the quality of received accommodations and how easy the process was for them to receive the accommodations they needed” added Pereira-Lima.

    “Investing in a culture that acknowledges disability as a valuable form of diversity will improve patient care.”

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • “Eggsplosions” and eyes don’t mix

    “Eggsplosions” and eyes don’t mix

    [ad_1]

    BYLINE: Tessa Roy

    Putting a hard-boiled egg in the microwave is making users popular on TikTok, but that fame could come with a hefty price. 

    The trend on the social media app involves microwaving hard boiled eggs, then slicing them so they explode.

    Grace Wang, M.D., P.h.D, an ophthalmologist at Michigan Medicine, says it can be dangerous when this explosion happens.

    The flying egg debris and steam can impact a large area, and possibly injure people in its vicinity. 

    “The hot steam and the hot egg along with the force of the explosion can really hit you in the face and cause burns, and not just to your skin. It can burn your eyes and cause injuries,” Wang said. 

    These explosions typically cause thermal injury to the eyes, Wang says. This means damaged tissue, peeling skin and scars on the eyes, all of which can cause a lot of pain. It can also harm the cells that assist in repairing tissue on the front of the eye.

    SEE ALSO: Beezin’:The dangerous TikTok trend involving Burt’s Bees 

    Sometimes, injuries can be severe enough to require medical treatments or put people at risk of further infection. In the worst cases, people can experience long term vision issues from scarring.  

    These “eggsplosions” have been well documented even before TikTok. It’s not clear why the trend became popular on the app, but Wang says social media fame may be part of the allure. 

    “I think a reason for doing it is partly curiosity about the sound it makes, plus it’s something you can challenge your friends to do,” Wang said.

    “These videos can get a lot of views or clicks online because the explosion is an exciting thing that happens.” 

    Wang says anyone who tries the trend, or those who accidentally microwave a hard-boiled egg without knowing it can explode, should seek medical attention if they are injured.

    SEE ALSO: The Barbie feet challenge isn’t worth your Ken-ergy

    However, Wang recommends steering clear of this or any other trend that can cause injuries, regardless of any potential social media clout. 

    “Don’t try it, because it’s not worth it. You can get a lot of painful injuries that could alter your face, your appearance and your vision,” she said.

    “I think it’s good for families, if they find out about these trends, to talk about them with their children. Kids are often seeing these videos and how much attention they can get, but they’re not necessarily seeing the consequences.” 

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • Logging on for health: More older adults use patient portals, but access and attitudes vary widely

    Logging on for health: More older adults use patient portals, but access and attitudes vary widely

    [ad_1]

    Newswise — Far more older adults these days log on to secure websites or apps to connect with their health information or have a virtual health care appointment, compared with five years ago, a new poll shows.

    Overall, 78% of people aged 50 to 80 have used at least one patient portal, up from 51% in a poll taken five years ago, according to findings from the University of Michigan National Poll on Healthy Aging. Of those with portal access, 55% had used it in the past month, and 49% have accounts on more than one portal.

    But the poll also reveals major disparities, with some groups of older adults less likely to use patient portals, or more likely to have concerns about them. Older adults with annual household incomes below $60,000, and those who are Black or Hispanic, have lower rates of portal use, and were less likely to say they’re comfortable using a portal, than respondents who are higher-income or non-Hispanic white.

    There were also differences among older adults who don’t use portals, or haven’t used one in three or more years. Those who say they’re in fair or poor health physically or mentally were much more likely to say they’re not confident about their ability to log in and navigate a portal than those with better physical or mental health.

    Even among older adults who use online portals, the poll shows many still prefer phone calls for some tasks like scheduling appointments or asking a medical question. Portal users in general said they prefer the portal to the phone when it comes to tasks such as getting test results and requesting refills of their prescriptions.

    The poll is based at the U-M Institute for Healthcare Policy and Innovation and supported by AARP and Michigan Medicine, the University of Michigan’s academic medical center.

    The jump in portal use between polls done in 2018 and 2023 likely happened in part due to the increase in use of telehealth visits, says Denise Anthony, Ph.D., the U-M School of Public Health researcher who worked on the poll.

    The pandemic spurred many health systems, physician groups and hospitals to support video visits within their secure websites and apps.

    “This change makes access to secure portals even more important for older adults who want to see their doctors and other health care providers virtually. It also makes the disparities we found in our poll even more troubling,” says Anthony, who chairs the Department of Health Management and Policy and studies use of telehealth and patient portals. “Improving the functionality and accessibility of portal systems, as well as providing more outreach and training to help patients understand and use portal systems, will be crucial to improving equity.”

    Many portals allow patients who have created their own accounts to also grant a loved one access to some or all of their information, so they can help manage their health care. The new poll shows that 49% of portal users have done so, up from 43% in 2018. Of all portal users, 40% have given access to a spouse or partner, with 48% of men doing so compared with 32% of women.

    “A growing body of evidence shows that patients who use portals to access their information are more likely to take an active role in their care and stick to the treatment plan their physicians and other providers recommend, which we know is likely to lead to better outcomes,” says poll director Jeffrey Kullgren, M.D., M.P.H., M.S., an associate professor of internal medicine at Michigan Medicine and physician and researcher at the VA Ann Arbor Healthcare System.

    “Health care organizations that offer portals, and providers working in those organizations, should make an effort to engage and support patients who have not yet activated a portal account, and to offer training to increase confidence and encourage the sharing of access with trusted loved ones,” he says. “This is especially important for patients who have complex health needs or multiple conditions.”  

    He notes that 27% of the poll respondents who have used a patient portal in the last year expressed an interest in more training. The percentage was higher among respondents who haven’t used a patient portal recently, and those who are Black, Hispanic or have incomes below $60,000.

    “Research shows that while more older Americans are embracing technology, nearly 22 million seniors still do not have wireline broadband access at home, limiting their access to essential digital health care services like patient portals,” said Indira Venkat, AARP Senior Vice President of Research. “Closing the digital divide among older adults is critical to improving their wellbeing, especially for vulnerable communities and individuals.”

    Michigan Medicine launched its portal, MyUofMhealth.org, in 2012. Like many health systems, it has continued to add online functions, from rapid test result access and paperless billing, to self-scheduling some types of appointments and having asynchronous chats with providers for urgent matters. Today, 20% of all outpatient visits with University of Michigan Health providers take place via video connections hosted in the portal.

    The poll report is based on findings from a nationally representative survey conducted by NORC at the University of Chicago for IHPI and administered online and via phone in January 2023 among 2,563 adults aged 50 to 80. The sample was subsequently weighted to reflect the U.S. population. For the previous patient portal poll, a different sample of older adults was asked about patient portal use, but both samples were weighted to reflect the population of U.S. adults aged 50 to 80.

    Read past National Poll on Healthy Aging reports and about the poll methodology.

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • Blood bank director welcomes FDA blood donation change that will affect members of LGBTQ community

    Blood bank director welcomes FDA blood donation change that will affect members of LGBTQ community

    [ad_1]

    The announcement by the U.S. Food and Drug Administration that it has finalized risk-based guidelines for blood donation related to sexual activity is being welcomed by the longtime director of the Blood Bank at Michigan Medicine, the University of Michigan’s academic medical center. 

    “The FDA guidance on individualized risk assessment of blood donors is an important step forward in assuring availability of blood for our patients while maintaining the highest level of safety,” said Robertson Davenport, M.D., director of transfusion medicine and professor of pathology. 

    “The FDA is making changes to how blood donors are screened based on high quality scientific evidence. Since the first implementation of indefinite deferral of men who have sex with men (MSM) there have been great strides made in donor testing and in the understanding of epidemiology of HIV. We now know that there are many MSM who are very low risk. Alternatively, we know that there are other donors who are at increased risk of HIV who were no covered under the previous deferral, such as heterosexuals with a new sexual partner and those who engage is certain sexual activities. The new individualized risk assessment more clearly focuses on potential donor who are at risk and allow for donation by low risk individuals regardless of sexual orientation. This is an important step forward in increasing blood donations.”

    Learn more about the Michigan Medicine Blood Bank, which recently moved to a new state-of-the-art space in University Hospital. 

    Davenport encourages all would-be blood donors who previously had been ineligible to donate under the former guidelines to monitor sites such as the American Red Cross page for the LGBTQ community for updates on when they may begin donating under the new guidelines.

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • “Turn-I-Kits” for Ukraine

    “Turn-I-Kits” for Ukraine

    [ad_1]

    BYLINE: Tessa Roy

    Newswise — When Russia’s War on Ukraine began, individuals around the world mobilized to support the Ukrainian people. Among those offering help is a group from Michigan Medicine’s Max Harry Weil Institute for Critical Care Research and Innovation.

    The Weil Institute, partnered with Precision Trauma LLC, was developing tourniquets for years in response to the Stop the Bleed Campaign, which began after the 2013 Boston Marathon bombing. In addition, the two were working to create tourniquets that were easier to use and more comfortable after application.

    They soon found another great need for the “Turn-I-Kit” devices they created.

    “We were just gearing up to make these available for public use and training, then the Ukraine war happened,” said Kevin Ward, MD, Executive Director of the Weil Institute and a veteran himself. “There’s not a clear battlefield in Ukraine, so civilian centers and civilian populations are now part of the battlefield landscape.”

    The Weil Institute and Precision Trauma have now donated 780 of their Turn-I-Kits to Ukraine. Turn-I-Kits meet all requirements of standard military-issue tourniquets and are fit to be used in hospitals or at various levels of care on the battlefield.

    They are designed for intuitive use for those who have little to no training – they’re slightly larger than a regular tourniquet and have a simple turnkey knob for easier tightening. Standard tourniquets can also be quite painful to apply because of their narrow bands. The Turn-I-Kits are uniquely designed with a significantly wider band, which reduces that discomfort.

    “Think of an octogenarian trying to apply a tourniquet to their spouse or a child – this is what we had in mind when designing these,” said Ward. “People in Ukraine are seeing explosions, building collapses, and gunshot wounds by high velocity military rifles. These create quite a bad wound. There are lots of opportunities to use these tourniquets to save a life in these settings.”

    Ward encourages everyone to learn how to use tourniquets, even if the chances of having to use one are rare. For now, he is grateful that more Ukrainians who need tourniquets will have them.

    “Ukraine is experiencing significant civilian casualties because of attacks on civilian population centers. In addition, much of the Ukrainian army is civilian – these are people who signed up with maybe limited experience and are volunteering to protect their country,” Ward said. “I have a lot of admiration for the Ukrainian people and their military. It’s an honor and a privilege to contribute in some small way to their fight to maintain their freedom.”  

    Disclosures: Ward is an inventor of the Turn-i-Kit and has equity in Precision Trauma, LLC.

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • U-M Health surgical team guides Zambia’s first total aortic arch replacement

    U-M Health surgical team guides Zambia’s first total aortic arch replacement

    [ad_1]

    BYLINE: Noah Fromson

    Newswise — Surgeons in Zambia completed the country’s first total aortic arch replacement – guided by a team from University of Michigan Health.

    The six-person surgical team traveled from Ann Arbor to Africa in late February to co-lead this case and several others at National Heart Hospital, a government-established, 120-bed facility in Lusaka, Zambia.

    The historic procedure to replace the ascending aorta and aortic arch of a 72-year-old patient took place on March 2. The patient’s echocardiogram revealed a potentially fatal aortic dissection that reached eight centimeters in diameter and extended into both his carotid arteries. The surgery, which lasted six hours, was uneventful with no complications.

    “It was a tremendous privilege to work with the providers at National Heart Hospital, as well as our experienced team from U-M, to perform this historic case in Zambia,” said Gorav Ailawadi, M.D., director of the U-M Health Frankel Cardiovascular Center and Helen F. and Marvin M. Kirsh Professor and chair of cardiac surgery at U-M Medical School.

    Zambia, a country of around 20 million people, has fewer than 10 cardiac specialists in both the government and private sector. Cardiovascular disease is the nation’s second leading cause of death.

    The National Heart Hospital began conducting cardiac surgeries in September 2021. The U-M Health team worked the recent cases with Chileshe Mutema, M.D., chief of cardiothoracic surgery at National Heart Hospital.

    In the past, Mutema says, expatriate cardiac surgeons were hired periodically to fly in for procedures, yet less than 1% of patients who needed cardiac surgery saw benefits.

    “Performing this case with U-M showed us what is possible and that the capacity to do complex cases comes with a knowledgeable, experienced and well-organized team with each team member doing their best,” Mutema said. “This was significant because we aspire for such a time when we can have such surgeries on our own, as long as we grow step by step consistently. It was a historical moment to perform surgeries and learn from Dr. Ailawadi and his team. And I believe, with the help of U-M, we can attain that level sooner.”

    The surgical team faced several challenges while operating in Zambia. Beyond the fact that no provider had repaired an aortic arch, supplies were limited in all cases.

    When performing operations in Ann Arbor, surgical teams employ a method called hypothermic circulatory arrest, or HCA; this temporarily cools the body and suspends blood flow while preserving brain function and preventing stroke.

    For the aortic arch replacement at National Heart Hospital, surgeons had no access to a multi-branch graft that allows them to employ circulatory arrest only once during a procedure. Instead, they had to tailor a straight tube graft that forced surgeons to subject the patient to two episodes of hypothermic arrest. The team also devised a way to maintain some blood flow in the brain through a blood vessel.

    In another case, a double valve replacement in a 49-year-old agriculture supervisor who could no longer work due to his symptoms, they ran out of tubing kits used to deliver medications and nutrients that keep the heart from beating during surgery.

    This time, the surgical team applied fibrillatory arrest, a challenging method to open the heart while it is still beating, to perform a mitral valve replacement. They also repaired the patient’s tricuspid valve – for which they needed to fashion a tricuspid ring out of a piece of felt.

    “While we were there, each member of our team played an important role and we all worked together seamlessly to ensure that the surgeries were performed safely and efficiently,” said Thuy Le, PA-C, advance practice provider manager of the U-M Health Frankel CVC Cardiac Surgery Operating Room. “With the understanding of anatomy and surgical techniques, our team was able to think critically and collaborate with our colleagues to find creative solutions when unexpected issues arose.”

    The success of the cases is very encouraging for the NHH, Mutema says, especially being a young program.

    “It’s humbling to see patients going back to normal life when not long ago it was a death sentence,” he said. “The patients are very grateful for adding more years to their lives and accessing costly life changing surgery from home in Zambia. We hope to have regular perioperative clinical meetings, collaborative capacity building and more camps so that U-M can help us develop a quality, sustainable cardiac surgery program in Zambia and the region.”

    This was an uplifting experience for the U-M team to share knowledge and techniques that can help the local team save the lives of Zambian patients for years to come, Ailawadi adds.

    “We hope to continue to help patients across the world by teaching local teams to perform these life-saving operations with the highest level of safety.”

    The U-M Health team in Zambia included Thuy Le, PA-C, Chris Douglas, C.C.P., Lauren Richey, M.D., Hillary Poulos, R.N., Sydney O’Shaughnessy, C.C.P.

     

     

     

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • How one state beat national surgery opioid trends

    How one state beat national surgery opioid trends

    [ad_1]

    Newswise — A statewide effort to treat the pain of surgery patients without increasing their risk of long-term dependence on opioids has paid off in Michigan, a study shows.

    In less than two years, the effort led to a 56% reduction in the amount of opioids patients received after having six different common operations, and a 26% drop in the chance that they would still be filling opioid prescriptions months after their surgical pain should have eased.

    Both of those drops beat national trends for similar patients, according to the new study published in Annals of Surgery by a team from Michigan Medicine, the University of Michigan’s academic medical center.

    Michigan patients having certain operations – for instance, to remove part of their colon – saw the biggest drops over the study period in how many opioids they received after their operations. They also had the biggest drop in risk of developing persistent opioid use, which the researchers define as filling opioid prescriptions for months or years after surgery, when their initial surgery-related prescription was intended for short-term use.

    The Michigan effort used prescribing guidelines based on real-world evidence about how many opioid doses surgery patients actually need to ease their pain, compared with what they were prescribed.

    Importantly, the guidelines don’t leave patients in pain. In fact, past research showed that surgery patients receiving smaller opioid prescriptions had similar pain outcomes and were just as satisfied with their pain care.

    “Tens of millions of people have operations in the U.S. every year, and most of them go home with a prescription for an opioid painkiller. Although they are meant for short-term use during recovery from surgery, unfortunately, some patients keep filling opioid prescriptions for months or years after surgery, which raises their risk of opioid use disorder, overdose, and death,” said Ryan Howard, M.D., M.S., the resident in the U-M Department of Surgery who led the new analysis. “Reducing those trends is a key part of addressing our national opioid problems.”

    A statewide team effort

    The achievement was driven by the Opioid Prescribing Engagement Network and the Michigan Surgical Quality Collaborative – both based at U-M – and by surgical team leaders at 70 hospitals across the state that take part in MSQC and have implemented OPEN guidelines.

    “Our study shows how voluntary prescribing guidelines, and involvement of surgical teams in choosing evidence-based pain care options, can really make a difference,” said senior author Chad Brummett, M.D., co-director of OPEN and director of pain research at Michigan Medicine’s Department of Anesthesiology. “Fewer opioids prescribed and dispensed means lower risk not only of persistent use, but also of risks to others in the household from unused opioid medication.”

    Helping patients get leftover opioids out of their homes and disposed of safely is another key goal of the opioid prescribing engagement network. They offer several free programs to Michigan organizations including free medication disposal pouches, permanent disposal boxes and medication take back event planning materials.

    Making Michigan the safest place for surgery

    The team showed that declines in Michigan – where these guidelines were implemented – outpaced the nation, and other Midwest states, by comparing records from tens of thousands of patients who had the six types of operations in Michigan and those who had them in other states.

    Their analysis spans almost four years before the prescribing guidelines were deployed statewide, and nearly two years afterward, from 2013 to mid-2019.

    They focused on patients covered by traditional Medicare, who had not filled an opioid prescription for a year before their operation, and who had not had a second operation in the six months after their index operation.

    The study focuses on nearly 25,000 Michigan patients and more than 118,600 non-Michigan patients who had minimally invasive gallbladder removal or appendix removal, minor or major hernia repairs, removal of part of the colon (colectomy), or hysterectomy.

    Those six types of operations were the first ones that focused on when developing and implementing prescribing guidelines based on opioid prescription fills and surveys of patients undergoing surgery. They were first published in October 2017, and have been added to ever since with guidelines for other types of surgical and dental procedures. The opioid prescribing engagement network recently published its first pediatric surgery prescribing guidelines.

    The 70 hospitals across Michigan where the guidelines were deployed account for the majority of surgical care in the state. The non-Michigan patients were a 20% sample of all traditional Medicare patients who had the same operations in the same timeframe.

    The researchers looked for signs of new persistent use of opioids, which means a patient filled an opioid prescription immediately after surgery, and then also filled at least one more opioid prescription in the three months after surgery, and another up to six months after surgery. They also looked at the total amount of opioids that patients received in the six months after their operation.

    Because opioid prescribing in general was trending downward in the mid-2010s, the researchers looked at differences between Michigan and national trends to see if there was any difference.

    Michigan outperforms the nation

    Michigan patients had a larger decrease in the rate of new persistent opioid use than their non-Michigan counterparts, with the two drops differing by about half a percentage point.

    This was driven especially by a 2.76 percentage-point reduction among those having colon surgery, and smaller but significant reductions among those having gallbladder and minor hernia operations. Patients having other operations had either no difference between Michigan and the rest of the nation, or a slight increase in Michigan for appendectomy.

    On the whole, Michigan surgical patients saw a faster drop in the size of the opioid prescriptions they filled, compared with those in other states having the same operations in the same time period.

    The difference was nearly 56 mg of opioids by the end of the study period, with significant drops in all types of surgery except laparoscopic appendectomy. Michigan patients started at about 200 mg morphine equivalents, and dropped to 89 mg morphine on average, while non-Michigan patients started at 218 mg morphine and dropped to 154 mg morphine.

    The size of dispensed opioid prescriptions to Michigan surgical patients was actually already lower than national surgical opioid prescribing before the guidelines, though persistent opioid use after surgery was higher in Michigan at 3.4% compared with 2.7%.

    When the researchers excluded cancer patients, or patients with substance issues, Michigan still outperformed the rest of the country in decreasing persistent use and reducing the size of prescriptions dispensed to patients.

    Michigan’s colon surgery patients had the biggest drop in both the amount of opioids they received and their chance of developing persistent use.

    The researchers also did additional comparisons of Michigan with a group of Midwestern states, and with Indiana and Wisconsin, as well as doing analyses that excluded cancer patients and patients who had previously been diagnosed with a substance use disorder. In all these cases, Michigan performed better than the nation.

    Both MSQC and OPEN receive funding from Blue Cross Blue Shield of Michigan. The opioid prescribing engagement network also has received funding from the Michigan Department of Health and Human Services and National Institutes of Health, as well as support from the U-M Institute for Healthcare Policy and Innovation.

    In addition to Howard and Brummett, the study’s authors are Andrew Ryan, Ph.D., formerly of the U-M School of Public Health, Hsou Mei Hu, Ph.D., M.B.A., of OPEN; Craig S. Brown, M.D., M.S., of Surgery; and OPEN co-directors Jennifer Waljee, M.D., M.P.H., M.S., Mark Bicket, M.D., Ph.D. and Michael Englesbe, M.D. Many of the authors are members of IHPI and the Center for Healthcare Outcomes and Policy.

    Paper cited: “Evidence-Based Opioid Prescribing Guidelines and New Persistent Opioid Use After Surgery,” Annals of SurgeryDOI: 10.1097/SLA.0000000000005792

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • The new insulin price cap: What you need to know

    The new insulin price cap: What you need to know

    [ad_1]

    BYLINE: Tessa Roy

    Newswise — In early March, Eli Lilly made headlines after announcing a new $35 price cap on insulin for individuals with private insurance. Novo Nordisk and Sanofi made their own price reduction announcements shortly after Eli Lilly’s move.

    Here, Rodica Pop-Busui, M.D., Ph.D., Larry D. Soderquist Professor of Diabetes and Associate Director for Clinical Research, Mentoring, and Development at the Elizabeth Weiser Caswell Diabetes Institute discusses the potential impacts of the new cost reduction on people with diabetes.

    Can you discuss the impact the new price caps will have for patients?

    Pop-Busui: Diabetes is the most expensive chronic disease in the United states. As many as one in four Americans compromise their health by rationing insulin because they cannot afford it, and as a result skip or ration doses to make ends meet. For millions of Americans, skyrocketing insulin prices have made it financially out of reach. Additionally, diabetes prevalence is inversely related to household income level, with the poorest communities seeing the highest rates.

    According to the National Institutes of Health, those who earn less than $30,000 per year are three times as likely to have diabetes than those who make over $80,000 per year; additionally, those lower on the socioeconomic status ladder are more likely to develop diabetes, experience more complications and die sooner than those higher up on the SES ladder. Moreover, Black and Hispanic individuals are more than 50% more likely to have diabetes than non-Hispanic white individuals and are 2.3 times more likely to die from diabetes than their white counterparts. 

    Prices for insulin nearly tripled between 2002 and 2013. Thus, there is an insulin affordability crisis in America that impacts over 90 million Americans living with diabetes. Often, they must choose between basic living expenses and lifesaving medication.

    The American Diabetes Association has been at the forefront and is the leading voice advocating for insulin affordability for years. The ADA is working to ensure that all people with diabetes have access to the care they need.  

    Would this have any impact on how insurers can cover insulin?

    Pop-Busui:  Policymakers must use co-pay caps and other policies to make diabetes treatment more affordable. The Inflation Reduction Act is helping 3.9 million Americans living with diabetes on Medicare to afford insulin. But millions are not able to afford their insulin, even with their employer insurance. 

    Representatives Angie Craig, Dan Kildee and Lucy McBath reintroduced the Affordable Insulin Now Act, creating a $35 monthly copay cap for insulin in commercial insurance plans. The legislation previously failed to pass, but the ADA is actively supporting it today.

    The ADA also supported the INSULIN Act, introduced by Senators Jeanne Shaheen and Susan Collins last year and continues to work with the Diabetes Caucus co-chairs to advance a price limit on insulin in commercial plans. 

    What implications does this have for other companies like Eli Lilly? Is it possible that others will follow in their footsteps?

    Pop-Busui: This step Eli Lilly is taking is an important one. By limiting cost-sharing for its insulin, it’s encouraging other insulin manufacturers to do the same.

    While we have been able to help achieve significant progress on the issue of insulin affordability, including Medicare’s new out-of-pocket cost cap on insulin, state copay caps and patient assistance developments from insulin developers, our work is far from done. For instance, a key area the ADA is focused on includes supporting insulin co-pay cap legislation in more than 10 states. States that have passed legislation include Alabama, Colorado, Connecticut, Delaware , District of Columbia, Illinois, Kentucky, Louisiana, Maine, Maryland, Minnesota, New Hampshire, New Mexico, New York, Oklahoma, Oregon, Rhode Island, Texas, Utah, Vermont, Virginia, Washington and West Virginia.

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • Doctor learns how to walk again after biking accident

    Doctor learns how to walk again after biking accident

    [ad_1]

    BYLINE: Valerie Goodwin

    Newswise — Like many during the early stages of the COVID-19 pandemic, Joseph Kolars, M.D., professor of medicine in the Division of Gastroenterology and Hepatology at the University of Michigan and his wife, Candace Kolars would take nice weather days as an opportunity to get outside and be active.

    In December 2020, the Kolars were taking one of their usual bike rides through Gallup Park in Ann Arbor when they noticed a runner had fallen on a slippery bridge. The pair quickly hit their brakes but proceeded to fall off their bikes. While Candace Kolars was unharmed, Joseph Kolars was in a lot of pain and couldn’t stand up.

    After calling 911, EMS arrived to find that not only could Joseph Kolars not stand, but his helmet was cracked. He was quickly whisked away to the University of Michigan Health System Emergency Department for evaluation.

    Joseph Kolars had numerous tests run on both his head and his legs. The results revealed that while his helmet had protected his head, his pelvis and femur absorbed the full brunt of the fall.

    A series of x-rays and CT scans showed that Joseph Kolars’s right femur had broken through the joint capsule, gone up through his pelvis, which shattered in the process. The staff at the ED quickly started trying to control Kolars’ pain while putting him into traction to pull his femur out of his pelvic area.

    “I don’t remember much from the ED, but I do remember them doing everything they could to make me feel comfortable,” said Joseph Kolars. “Everyone who helped me was very efficient.”

    After all the ED tests were run, Jaimo Ahn, M.D., an orthopaedic surgeon at Michigan Medicine, assessed the damage of the injury and started working on a plan of operation for Joseph Kolars.

    While his injury was severe, Ahn was able to quickly identify the injury as a “high energy” acetabular fracture, a type of fracture that has been researched for decades. Within 24 hours of arriving to the ED, Ahn was able to start working with Joseph Kolars on a plan of action for surgery.

    Fixing an injury like this requires a lot of surgical trauma to the body. Almost all surgeries require cutting through muscles and tissues to get to the desired location. The larger the incision, the more trauma, blood loss, risk of infection, and more difficult recovery.

    “Surgery is just controlled trauma to the body,” said Ahn. “The less trauma we can cause, the easier it is for the patient to recover.” 

    Ahn proposed a hybrid procedure that would have a smaller incision and less risk and an easier recovery.

    “Dr. Ahn presented this alternative method with lots of confidence,” said Joseph Kolars. “His confidence in the procedure is what convinced me this was the right choice and that it would pan out well.”

    This procedure used more indirect methods to bring the pieces back together. Pins were used during the procedure to help steady the bones so they could be put back in place and guide the fixation metal to where it needs to go. The plates and screws were left in the pelvis to help hold the bone where it needs to be and steady the area so Joseph Kolars could start walking again during recovery.

    The CT scan that was done before surgery allowed Ahn to see every fracture in full detail down to the millimeter. This allowed for more precise placements of the surgical hardware when it came to the procedure and piecing the pelvic bone back together.

    “Some people would describe fracture care as a mix of carpentry and gardening,” said Ahn. “The carpentry aspect is using a hard material that we need to be able to position and fix into place. We are still working with a living organism and need to make sure there is ample blood flow to support what is being done, that is the gardening.

    Getting back on the bike

    After surgery, Joseph Kolars spent six days in the hospital before being discharged. Even though his wife could not visit due to COVID-related restrictions, she felt kept in the loop about what was going on.

    “Dr. Ahn kept good communication with Candace Kolars and was able to inspire confidence in her that this procedure was the right choice,” said Joseph Kolars. “We were both very impressed with the communication from all the staff. Candace Kolars felt like she was being kept in the loop on everything as if she was there.”

    Candace Kolars would receive regular phone calls and facetimes from Ahn, the staff, and Joseph Kolars himself to be kept up to date with the care that he was receiving.

    Ahn and Joseph Kolars both mentioned that it is not always easy for doctors to be good patients.

    “We have a tendency as doctors to feel like we should be leading the critical treatment decisions,” said Ahn. “Joseph Kolars did a great job of being an engaged patient rather than directing care and that engagement can make a real positive difference.”

    Before being discharged from the hospital, physical therapy and occupational therapy teams created a specialized plan for Joseph Kolars’s recovery at home. Due to the nature of the injury, Joseph Kolars couldn’t ride in a car, so the therapists were sent to his house one to three times per week help with rehabilitation.

    Joseph Kolars was unsure if he would be able to walk again or make a full recovery due to the severity of the injury. Thanks to his care teams, he was able to walk again by April of 2021.  Today, Joseph Kolars and his wife still enjoy riding their bikes for as far as 40 miles.

    “The care I received from everyone during my stay in the hospital and after was phenomenal,” said Joseph Kolars. “I’m extremely grateful for everyone who worked on my case.”

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • High fat diet activates early inflammation in mouse brains, supports link to neurologic disease

    High fat diet activates early inflammation in mouse brains, supports link to neurologic disease

    [ad_1]

    Newswise — Researchers at Michigan Medicine have discovered that a high-fat diet promotes an early inflammatory response in the brains of mice through an immune pathway linked to diabetes and neurologic diseases, suggesting a possible bridge between metabolic dysfunction and cognitive impairment. 

    For the study, published in Frontiers in Immunology, investigators analyzed activation of the cGAS/STING immune pathway in a high-fat diet mouse model of prediabetes and cognitive impairment or dementia. Though early changes in cognition were not detected, results reveal insulin resistance, as well as inflammatory activation of cGAS/STING and the microglia, the brain’s immune cells, within three days of feeding.

    “While there is evidence suggesting a role for cGAS/STING in obesity and diabetes, both of which make patients more vulnerable to cognitive impairment or dementia, its role in the brain has not been previously studied,” said Sarah Elzinga, Ph.D., first author and a postdoctoral fellow at the NeuroNetwork for Emerging Therapies at Michigan Medicine.

    “We now see that this pathway is involved in an early burst of immune response in the microglia, which plays a critical role in Alzheimer’s disease and related dementias. If microglia are activated in the hippocampus under high-fat diet conditions, that may contribute to inflammation and degeneration in the nervous system and eventual cognitive impairment or dementia.”

    Obesity and diabetes are significantly associated with the development of dementia and other neurologic diseases. Elzinga and the research team say further research is needed to examine if inhibiting the cGAS/STING pathway is a possible treatment target for reversing or preventing harmful changes in the brains of people who develop cognitive impairment or dementias.

    “Innovative ideas that can lead to novel treatment paradigms are critical in our battle against Alzheimer’s disease,” said senior author Eva Feldman, M.D., Ph.D., James W. Albers Distinguished Professor at U-M, the Russell N. DeJong Professor of Neurology and director of the NeuroNetwork for Emerging Therapies at Michigan Medicine. “This research with cGAS/STING is one such innovation and opens doors to exciting new therapeutic possibilities.”

    Additional authors include Rosemary Henn, Ph.D., Benjamin J. Murdock, Ph.D., Bhumsoo Kim, Ph.D., John M. Hayes, Ian Webber-Davis, Sam Teener, Crystal Pacut, Stephen I. Lentz, Ph.D., all of Michigan Medicine, Faye Medelson

    Funding for this study was provided in part by the NIH National Institute of Diabetes and Digestive Kidney Disease and the National Institute on Aging.

    Paper cited: “cGAS/STING and innate brain inflammation following acute high-fat feeding,” Frontiers in ImmunologyDOI: 10.3389/fimmu.2022.1012594

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • Nearly 1/3 of people with chronic pain turn to cannabis

    Nearly 1/3 of people with chronic pain turn to cannabis

    [ad_1]

    Newswise — As more U.S. states legalize cannabis (also known as marijuana) for medical and recreational use, increasing numbers of people are experimenting with it for pain relief. According to a new study published in JAMA Network Open, almost a third of patients with chronic pain reported using cannabis to manage it.

    More than half of the 1,724 adults surveyed reported that using cannabis led them to decrease the use of pain medications, including prescription opioids and over-the-counter analgesics. Cannabis also effected the use of other non-drug related pain relief methods to various degrees: some people indicated that cannabis led them to turn less often to techniques that many clinical guidelines recommend as first-line therapies such as physical therapy and cognitive behavioral therapy, while others with chronic pain increased their use of such treatments.

    “The fact that patients report substituting cannabis for pain medications so much underscores the need for research on the benefits and risk of using cannabis for chronic pain,” said Mark Bicket, M.D., Ph.D., Assistant Professor in the Department of Anesthesiology and Co-Director of the Michigan Opioid Prescribing Engagement Network.

    Paper cited: “Use of cannabis and other pain treatments among adults with chronic pain in US states with medical cannabis programs,” JAMA Network Open. DOI: 10.1001/jamanetworkopen.2022.49797

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • High levels of ammonia in colon tumors inhibits T cell growth and response to immunotherapy

    High levels of ammonia in colon tumors inhibits T cell growth and response to immunotherapy

    [ad_1]

    Newswise — High levels of ammonia in tumors leads to fewer T cells and immunotherapy resistance in mouse models of colorectal cancer, new findings from the University of Michigan Rogel Cancer Center revealed. Researchers found that ammonia inhibits the growth and function of T cells, which are vital for anti-tumor immunity. The findings appear in Cell Metabolism.

    “We identified the mechanism of how ammonia dysregulates T cell function and showed that reducing ammonia levels using FDA-approved drugs for hyperammonemia can reduce tumor size in several different models including metastatic colorectal cancer,” says Hannah Bell, Ph.D., a postdoctoral fellow in cancer biology and author on this paper. “Use of this drug also synergizes with immunotherapy. If you treat the mice with immunotherapy when you also treat them with this ammonia reducing agent, you’re able to sensitize the tumors to treatment.”

    “Most colorectal cancers are insensitive to immune therapies,” adds Yatrik Shah, Ph.D., Horace W. Davenport Collegiate Professor of Physiology and first author of the study. “We’ve found that one of the mechanisms that leads to this resistance is likely the high level of ammonia that accumulates in the microenvironment.”

    Bell explains that while there are many factors that contribute to immunotherapy resistance, there are few therapeutic interventions that can reactivate therapy sensitivity. “Our study shows that this is a relatively safe and FDA-approved method that could work alongside immunotherapy to make treatment more effective for patients. This new method provides a potentially direct avenue to treat tumors and reactivate the immune system.”

    How does ammonia accumulate in colorectal tumors in the first place? Ammonia levels are regulated by a balance of production and cellular detoxification. Most ammonia is generated by the microbiota, but Bell and Shah’s work suggests that increased production of ammonia is not what results in accumulation. “Our work demonstrates that tumors have lost the ability to detoxify ammonia leading to build up,” said Shah.

    Further, the accumulation of ammonia is likely not isolated to just colorectal tumors. Shah says this discovery may open doors in explaining resistance to other cancer types as well. “Only about 20-30% of all cancer patients are sensitive to immunotherapy. 70% of patients don’t derive any benefit from it,” Shah said. “Now, we have a mechanism that could explain this resistance in tumors beyond colon cancer.”

    More work needs to be done before researchers can bring these findings into the clinic.

     

    Additional Authors: Amanda K. Huber; Rashi Singhal; Navyateja Korimerla; Ryan J. Rebernick; Roshan Kumar; Marwa O. El-derany; Peter Sajjakulnukit; Nupur K. Das; Samuel A. Kerk; Sumeet Solanki; Jadyn G. James; Donghwan Kim; Li Zhang; Brandon Chen; Rohit Mehra; Timothy L. Frankel; Balázs Győrffy; Eric R. Fearon; Marina Pasca di Magliano; Frank J. Gonzalez; Ruma Banerjee; Daniel R. Wahl; Costas A. Lyssiotis; Michael Green

     

    COI: N/A

     

    Funding: NIH grants: R01CA148828, R01CA245546, R01DK095201, R37CA237421, R01CA248160, R01CA244931 (C.A.L); UMCCC Core Grant P30CA046592 and R35GM130183; T32 training grant GM008322 and F30CA257292. American Heart Association (826245) and NIH grant F30CA257292. NIH F31 fellowship (F31CA247457) and NIH fellowship (F99CA264414).CMB Graduate Program T32GM007315. American Physiological Society postdoctoral fellowship (032650). Crohn’s and Colitis Foundation Research fellowship award (623914) and the American Heart Association postdoctoral fellowship (19POST34380588). National Research, Development and Innovation Office (PharmaLab, RRF-2.3.1-21-2022-00015 and 2020-1.1.6-JÖVŐ-2021-00013).

     

    DOI: “Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer,” Cell Metabolism. DOI: 10.1172/JCI143691

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link

  • Cost concerns keep older adults from seeking emergency care

    Cost concerns keep older adults from seeking emergency care

    [ad_1]

    Newswise — Worries about what emergency care might cost them have kept some older adults from seeking medical attention even when they felt they might need it, a new study shows.

    In all, 22% of older adults who may have needed care from the emergency department didn’t go because of concerns about what they might have to pay, according to the new findings published in the American Journal of Managed Care.

    People in their 50s and early 60s, women, those who lack health insurance, people with household incomes under $30,000, and those who say their mental health is fair or poor were most likely to say they’d avoided getting emergency care because of cost concerns.

    The study, based on a survey conducted in June 2020, asked older adults to think back on the previous two years, including the first months of the COVID-19 pandemic.

    Even among those who hadn’t had a medical emergency in this time, worries about what an emergency visit might cost them were high. Four out of five older adults said they were concerned about the cost of emergency care (35% somewhat concerned and 45% very concerned, and 18% were not confident they could afford a visit.

    The data from the study come from the National Poll on Healthy Aging, based at the University of Michigan Institute for Healthcare Policy and Innovation and supported by AARP and Michigan Medicine, U-M’s academic medical center. The findings build on the poll report published earlier and are based on responses from a nationally representative sample of 2,074 people age 50 to 80.

    The findings confirm the experience of lead author Rachel Solnick, M.D., M.Sc., who trained in IHPI’s National Clinician Scholars Program before joining the faculty at the Icahn School of Medicine at Mount Sinai Health System in New York.

    “As an emergency physician, I have seen patients come to the emergency room having postponed their care. They often come in sicker than they would have been had they received care sooner,” she said. “That scenario is what I find most alarming in this survey’s findings. Some groups that are medically vulnerable or have suffered worse outcomes from COVID-19 were more likely to report cost-related avoidance of the ER than their counterparts. These findings highlight the importance of reducing the number of uninsured individuals and the need for insurers to clearly communicate coverage for emergency services.”

    Keith Kocher, M.D., the study’s senior author and an associate professor of emergency medicine at U-M, notes that the federal No Surprises Act was enacted after the study was done. That act seeks to reduce “surprise billing” for emergency care when a privately insured person receives it from hospitals or providers outside their health insurance plan’s network. At the time of the study, Medicare and Medicaid already prohibited emergency care providers from doing this kind of “balance billing.”

    Even so, a person with private insurance might owe hundreds of dollars in co-pays or deductibles for an emergency visit, the authors note. That’s especially true for people with high-deductible health plans, which are growing in enrollment.

    Even though the percentage of older adults who lack any health insurance is small (4% of the study sample), they were 35% more likely to say they were not confident they could afford emergency care. Solnick notes that both the pandemic’s economic impacts, and the decision by more than a dozen states including Texas and Florida to not expand Medicaid to all low-income adults, mean that millions of people may face paying out of pocket for emergency visits.

    American Journal of Managed Care, 2023;29(4): In Press, https://www.ajmc.com/view/older-adults-perspectives-on-emergency-department-costs-during-covid-19

    [ad_2]

    Michigan Medicine – University of Michigan

    Source link