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Tag: illegal drugs

  • UN human rights chief says US strikes on alleged drug boats are ‘unacceptable’

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    The U.N. human rights chief said Friday that U.S. military strikes against boats in the Caribbean Sea and eastern Pacific Ocean allegedly carrying illegal drugs from South America are “unacceptable” and must stop.The U.N. High Commissioner for Human Rights, Volker Türk, called for an investigation into the strikes, in what appeared to mark the first such condemnation of its kind from a United Nations organization.Ravina Shamdasani, a spokeswoman for Türk’s office, relayed his message Friday at a regular U.N. briefing: “These attacks and their mounting human cost are unacceptable. The U.S. must halt such attacks and take all measures necessary to prevent the extrajudicial killing of people aboard these boats.”She said Türk believed “airstrikes by the United States of America on boats in the Caribbean and in the Pacific violate international human rights law.”President Donald Trump has justified the attacks on the boats as a necessary escalation to stem the flow of drugs into the United States, but the campaign against drug cartels has been divisive among countries in the region.The strikes and the U.S. military’s growing presence near Venezuela have stoked fears that the Trump administration could try to topple Venezuelan President Nicolás Maduro, who faces charges of narcoterrorism in the United States.Asked Friday if he’s considering land strikes in Venezuela, Trump said, “No.” He did not elaborate as he spoke to reporters aboard Air Force One as he headed to Florida for the weekend.Speaking earlier this week from the USS George Washington aircraft carrier in Japan, Trump noted the U.S. attacks at sea and reiterated that “now we’ll stop the drugs coming in by land.”U.S. Defense Secretary Pete Hegseth on Wednesday announced the latest U.S. military strike in the campaign, against a boat he said was carrying drugs in the eastern Pacific Ocean. All four people aboard were killed. It was the 14th strike since the campaign began in early September, while the death toll has grown to at least 61.Shamdasani noted the U.S. explanations of the efforts as an anti-drug and counterterrorism campaign, but said countries have long agreed that the fight against illicit drug trafficking is a law enforcement matter governed by “careful limits” placed on the use of lethal force.Intentional use of lethal force is allowed only as a last resort against someone representing “an imminent threat to life,” she said. “Otherwise, it would amount to a violation of the right of life and constitute extrajudicial killings.”The strikes are taking place “outside the context” of armed conflict or active hostilities, Shamdasani said.

    The U.N. human rights chief said Friday that U.S. military strikes against boats in the Caribbean Sea and eastern Pacific Ocean allegedly carrying illegal drugs from South America are “unacceptable” and must stop.

    The U.N. High Commissioner for Human Rights, Volker Türk, called for an investigation into the strikes, in what appeared to mark the first such condemnation of its kind from a United Nations organization.

    Ravina Shamdasani, a spokeswoman for Türk’s office, relayed his message Friday at a regular U.N. briefing: “These attacks and their mounting human cost are unacceptable. The U.S. must halt such attacks and take all measures necessary to prevent the extrajudicial killing of people aboard these boats.”

    She said Türk believed “airstrikes by the United States of America on boats in the Caribbean and in the Pacific violate international human rights law.”

    President Donald Trump has justified the attacks on the boats as a necessary escalation to stem the flow of drugs into the United States, but the campaign against drug cartels has been divisive among countries in the region.

    The strikes and the U.S. military’s growing presence near Venezuela have stoked fears that the Trump administration could try to topple Venezuelan President Nicolás Maduro, who faces charges of narcoterrorism in the United States.

    Asked Friday if he’s considering land strikes in Venezuela, Trump said, “No.” He did not elaborate as he spoke to reporters aboard Air Force One as he headed to Florida for the weekend.

    Speaking earlier this week from the USS George Washington aircraft carrier in Japan, Trump noted the U.S. attacks at sea and reiterated that “now we’ll stop the drugs coming in by land.”

    U.S. Defense Secretary Pete Hegseth on Wednesday announced the latest U.S. military strike in the campaign, against a boat he said was carrying drugs in the eastern Pacific Ocean. All four people aboard were killed. It was the 14th strike since the campaign began in early September, while the death toll has grown to at least 61.

    Shamdasani noted the U.S. explanations of the efforts as an anti-drug and counterterrorism campaign, but said countries have long agreed that the fight against illicit drug trafficking is a law enforcement matter governed by “careful limits” placed on the use of lethal force.

    Intentional use of lethal force is allowed only as a last resort against someone representing “an imminent threat to life,” she said. “Otherwise, it would amount to a violation of the right of life and constitute extrajudicial killings.”

    The strikes are taking place “outside the context” of armed conflict or active hostilities, Shamdasani said.

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  • US warships’ Caribbean mission will divert drugs to the Pacific, experts warn

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    (CNN) — The deployment of US warships in the Caribbean to counter drug-trafficking could simply divert the problem to the Pacific, experts in the region warn.

    While much attention has focused on the political tension between the United States and Venezuela – even more so after a strike on an alleged Venezuelan drug boat on Tuesday – security specialists warn that the focus on Caribbean trafficking routes by American ships could have serious, unintended consequences for countries struggling to prevent drug flows on the Pacific corridor – such as Ecuador, Peru and Colombia.

    “What’s going to happen is that, by blocking this Caribbean corridor, drug traffickers will avoid continuing to transport drugs through that route, because it’s more dangerous, and they’ll incur greater losses. They’ll redirect the flow of drugs,” former Ecuadorian Army Intelligence chief Mario Pazmiño told CNN.

    Ecuador is one of the most violent countries in Latin America due to transnational organized crime and has the third-highest drug seizures after the United States and Colombia, according to the UN Office on Drugs and Crime.

    Various drug trafficking routes operate from the South American country to Central America, the United States and Europe, where a series of Ecuadorian, Colombian, Mexican and European criminal networks converge.

    Pazmiño thinks these routes will get only more popular with traffickers as the Caribbean routes are squeezed off.

    “This flow of drugs will no longer leave through Colombia or Venezuela. They will try to use Ecuadorian ports, which are one of our country’s greatest weaknesses and through which drugs are constantly leaving,” he warned.

    Indeed, Pazmiño believes this effect is already in play.

    On August 25, Ecuador’s Guayaquil Port Authority declared a state of emergency due to rising insecurity and constant extortion threats, which it claims are putting the integrity of the port infrastructure and personnel at risk.

    “The facilities of the Guayaquil Port Authority, as well as the personnel working there, are in imminent danger, given that threats have been made to kidnap the crew and pilots and attack vessels,” it said.

    Pazmiño believes the situation is closely linked to the military tension in Caribbean waters, and shows the ability of transnational crime to divert its trafficking routes.

    The Ecuadorian Navy recently reported that it has intensified its patrols and military operations against drug traffickers.

    On August 24, authorities seized 10 tons of drugs with the help of the US Coast Guard, which is providing support under military agreements signed in 2023.

    Traffickers ‘take advantage’ as threat to Maduro grows

    Daniel Pontón, an expert in criminal policy and crime control at Ecuador’s Institute of Advanced National Studies, said that controlling the Pacific corridor was becoming a much more complex task.

    “Drug traffickers know how to take advantage of any moment or vulnerability. Ecuador and other countries in the region need capabilities and cooperation. Joint action is required because the Navy’s capacity is limited,” Pontón added.

    Meanwhile, Michelle Maffei, a researcher on international organized crime, conflict, and violence, warned that militarizing the fight against criminal gangs could have the opposite effect to what is intended.

    “What this will force is another political conflict. It won’t be a strategy against organized crime. The United States is focused on the Maduro government (in Venezuela). While they’re focused on removing Maduro, the illegal and criminal economy will move more drugs, using semi-submersible vessels or contaminated containers with greater vigor, because they know their focus is on something else,” warns Maffei.

    Maffei said authorities should instead focus on fighting corruption.

    “We need to implement a radical reform of the judicial system in Ecuador. We have prosecutors who don’t work, judges who are bought off, and lawyers who are also bought off by organized crime groups. If this doesn’t happen in Ecuador, nothing good will come of it,” she added.

    Pazmiño also had suggestions for how to combat the problem: “Strengthening the northern border with Colombia, creating a joint task force to cover the entire northern border and making it difficult and impossible for cocaine to spill into Ecuadorian territory.”

    Even without increased drug flows, Ecuador is experiencing severe internal violence and recently reported record homicide numbers amid fighting between organized crime gangs. So far this year, the Ministry of the Interior has recorded 5,268 intentional homicides. In 2024, the year ended with 7,062 violent deaths. In 2023, there were 8,248.

    The Daniel Noboa administration has called on the international community to support the fight against transnational crime.

    But while the region’s eyes are focused on the Caribbean Sea, experts hope this will not lead to an increase in violence and mafia activity in the key areas of cocaine trafficking in the Pacific.

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    Ana Maria Canizares and CNN

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  • Long-elusive Mexican drug lord Ismael ‘El Mayo’ Zambada pleads guilty in US

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    Former Mexican cartel kingpin Ismael “El Mayo” Zambada pleaded guilty Monday to U.S. drug trafficking charges, saying he was sorry for helping to flood the U.S. with cocaine, heroin and other illicit substances and for fueling deadly violence in Mexico.“I recognize the great harm illegal drugs have done to the people of the United States, of Mexico, and elsewhere,” he said through a Spanish-language interpreter. “I take responsibility for my role in all of it and I apologize to everyone who has suffered or been affected by my actions.”Under the leadership of Zambada and Joaquín “El Chapo” Guzmán, the Sinaloa cartel evolved from a regional player into the largest drug trafficking organization in the world, prosecutors say.“Culpable,” Zambada said, using the Spanish word for “guilty,” as he entered his plea.He acknowledged the extent of the Sinaloa operation, including underlings who built relationships with cocaine producers in Colombia, oversaw the importation of cocaine to Mexico by boat and plane and the smuggling of the drug across the U.S.-Mexico border. He acknowledged that people working for him paid bribes to Mexican police and military commanders “so they could operate freely,” going all the way back to when the cartel was just starting out.Zambada was arrested in Texas last year. He entered his plea two weeks after prosecutors said they wouldn’t seek the death penalty against him, a development that his attorney has called an important step in resolving the case.The lawyer, Frank Perez, said outside court Monday that “the outcome was good,” adding that Zambada “wanted to accept responsibility, and he did.”Zambada, 77, is due to be sentenced Jan. 13 to life in prison.He traced his involvement in the illegal drug business to his teenage years, when — after leaving school with a sixth-grade education — he planted marijuana for the first time in 1969. He said he went on to sell heroin and other drugs, but especially cocaine. From 1980 until last year, he and his cartel were responsible for transporting at least 1.5 million kilograms of cocaine, “most of which went to the United States,” he said.Prosecutors said in his indictment that he and the cartel also trafficked in fentanyl and methamphetamine.Considered a good negotiator, Zambada was seen as the cartel’s strategist and dealmaker who was more involved in its day-to-day doings than the more flamboyant Guzmán. Nevertheless, prosecutors have said Zambada also was enmeshed in the group’s violence, at one point ordering the murder of his own nephew.Zambada pleaded guilty to charges of engaging in a continuing criminal enterprise between 1989 and 2024 and racketeering conspiracy, which encompasses involvement in a number of crimes from 2000 to 2012.Prosecutors say he presided over a violent, highly militarized cartel with a private security force armed with powerful weapons and a cadre of “sicarios,” or hitmen, that carried out assassinations, kidnappings and torture. He acknowledged in his plea that he “directed people under my control to kill others” to serve the cartel’s interests.“Many innocent people were also killed,” he said in an eight-minute address to the court Monday.Zambada appeared momentarily unsteady as he arrived in a Brooklyn federal courtroom; a marshal grabbed his arm to direct him to his seat among his attorneys at the defense table.As Judge Brian M. Cogan described the charges in Zambada’s plea agreement, the bearded ex-Sinaloa boss sat attentively, at times brushing his right hand through his white hair.Guzmán was sentenced to life behind bars following his conviction in the same federal court in Brooklyn in 2019.The Sinaloa cartel is Mexico’s oldest criminal group, with various incarnations dating to the 1970s. It is a drug trafficking power player: A former Mexican cabinet member was convicted of taking bribes to help the cartel.U.S. law enforcement sought Zambada for more than two decades, but he was never arrested in any country until he arrived in Texas last year on a private plane with one of Guzmán’s sons, Joaquín Guzmán López. Guzmán López has pleaded not guilty to federal drug trafficking charges in Chicago; his brother, Ovidio Guzmán López, pleaded guilty last month.Zambada has said he was kidnapped in Mexico and taken against his will to the U.S.Zambada’s arrest touched off deadly fighting in Mexico between rival Sinaloa cartel factions, apparently pitting his loyalists against backers of Guzmán’s sons, dubbed the Chapitos — a term that translates to “little Chapos.”Associated Press writer Jennifer Peltz contributed.

    Former Mexican cartel kingpin Ismael “El Mayo” Zambada pleaded guilty Monday to U.S. drug trafficking charges, saying he was sorry for helping to flood the U.S. with cocaine, heroin and other illicit substances and for fueling deadly violence in Mexico.

    “I recognize the great harm illegal drugs have done to the people of the United States, of Mexico, and elsewhere,” he said through a Spanish-language interpreter. “I take responsibility for my role in all of it and I apologize to everyone who has suffered or been affected by my actions.”

    Under the leadership of Zambada and Joaquín “El Chapo” Guzmán, the Sinaloa cartel evolved from a regional player into the largest drug trafficking organization in the world, prosecutors say.

    “Culpable,” Zambada said, using the Spanish word for “guilty,” as he entered his plea.

    He acknowledged the extent of the Sinaloa operation, including underlings who built relationships with cocaine producers in Colombia, oversaw the importation of cocaine to Mexico by boat and plane and the smuggling of the drug across the U.S.-Mexico border. He acknowledged that people working for him paid bribes to Mexican police and military commanders “so they could operate freely,” going all the way back to when the cartel was just starting out.

    Zambada was arrested in Texas last year. He entered his plea two weeks after prosecutors said they wouldn’t seek the death penalty against him, a development that his attorney has called an important step in resolving the case.

    The lawyer, Frank Perez, said outside court Monday that “the outcome was good,” adding that Zambada “wanted to accept responsibility, and he did.”

    Zambada, 77, is due to be sentenced Jan. 13 to life in prison.

    He traced his involvement in the illegal drug business to his teenage years, when — after leaving school with a sixth-grade education — he planted marijuana for the first time in 1969. He said he went on to sell heroin and other drugs, but especially cocaine. From 1980 until last year, he and his cartel were responsible for transporting at least 1.5 million kilograms of cocaine, “most of which went to the United States,” he said.

    Prosecutors said in his indictment that he and the cartel also trafficked in fentanyl and methamphetamine.

    Considered a good negotiator, Zambada was seen as the cartel’s strategist and dealmaker who was more involved in its day-to-day doings than the more flamboyant Guzmán. Nevertheless, prosecutors have said Zambada also was enmeshed in the group’s violence, at one point ordering the murder of his own nephew.

    Zambada pleaded guilty to charges of engaging in a continuing criminal enterprise between 1989 and 2024 and racketeering conspiracy, which encompasses involvement in a number of crimes from 2000 to 2012.

    Prosecutors say he presided over a violent, highly militarized cartel with a private security force armed with powerful weapons and a cadre of “sicarios,” or hitmen, that carried out assassinations, kidnappings and torture. He acknowledged in his plea that he “directed people under my control to kill others” to serve the cartel’s interests.

    “Many innocent people were also killed,” he said in an eight-minute address to the court Monday.

    Zambada appeared momentarily unsteady as he arrived in a Brooklyn federal courtroom; a marshal grabbed his arm to direct him to his seat among his attorneys at the defense table.

    As Judge Brian M. Cogan described the charges in Zambada’s plea agreement, the bearded ex-Sinaloa boss sat attentively, at times brushing his right hand through his white hair.

    Guzmán was sentenced to life behind bars following his conviction in the same federal court in Brooklyn in 2019.

    The Sinaloa cartel is Mexico’s oldest criminal group, with various incarnations dating to the 1970s. It is a drug trafficking power player: A former Mexican cabinet member was convicted of taking bribes to help the cartel.

    U.S. law enforcement sought Zambada for more than two decades, but he was never arrested in any country until he arrived in Texas last year on a private plane with one of Guzmán’s sons, Joaquín Guzmán López. Guzmán López has pleaded not guilty to federal drug trafficking charges in Chicago; his brother, Ovidio Guzmán López, pleaded guilty last month.

    Zambada has said he was kidnapped in Mexico and taken against his will to the U.S.

    Zambada’s arrest touched off deadly fighting in Mexico between rival Sinaloa cartel factions, apparently pitting his loyalists against backers of Guzmán’s sons, dubbed the Chapitos — a term that translates to “little Chapos.”

    Associated Press writer Jennifer Peltz contributed.

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  • Biden Admin to Loosen Marijuana Laws, Some Advocates Say It’s Nothing – Medical Marijuana Program Connection

    Biden Admin to Loosen Marijuana Laws, Some Advocates Say It’s Nothing – Medical Marijuana Program Connection

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    President Joe Biden’s administration will reportedly loosen laws regulating cannabis (marijuana), which some advocates say amounts to only a symbolic gesture that will ultimately change nothing.

    The president will reportedly move cannabis from the maximally restrictive Schedule I to the minimally restrictive Schedule III of the Controlled Substance Act (CSA), according to the Guardian.

    “That would lessen the tax burden on businesses selling the drug in states where it is legal and potentially change how police agencies view enforcement of marijuana laws,” noted the outlet.

    David Culver, senior vice president of public affairs for the U.S. Cannabis Council, a trade group, said that lowering the restriction to Schedule III will be the turnaround that the cannabis industry desperately needs.

    “If it’s going to be finalized at schedule III, it’s going to be the moment that the industry can turn the corner and we begin to see the growth in the cannabis space amongst the legal operators that we’ve been waiting on for so long,” said Culver.

    Some advocates have said the move amounts to little more than a symbolic gesture that will do little to eliminate the burden that private cannabis sellers and growers experience. For instance, while 38 states have approved cannabis for medical or commercial use, the substance still faces the same restrictions as heroin on the federal level. Despite it being legal in certain states, the industry has had to contend with…

    Original Author Link click here to read complete story..

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  • BOC seizes P805K worth of high-grade marijuana declared as ‘filter’ – Medical Marijuana Program Connection

    BOC seizes P805K worth of high-grade marijuana declared as ‘filter’ – Medical Marijuana Program Connection

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    James Relativo – Philstar.com

    December 2, 2023 | 6:09pm

    MANILA, Philippines — The Bureau of Customs-Port of Clark seized 488 grams of high-grade marijuana (kush) with an estimated value of P805,200 concealed inside a parcel declared as a “replacement filter” from California, USA.

    The parcel underwent x-ray scanning and K9 sniffing, which both indicated the possible presence of illegal narcotics.

    “Physical examination was immediately conducted which resulted in the findings of dried leaves and fruiting tops suspected to be High-Grade Marijuana or Kush,” said the BOC on Saturday.

    “Samples were then taken and turned over to PDEA for chemical laboratory analysis which confirmed the presence of Marijuana, a dangerous drug under R.A. No. 9165.”

     

     

    A warrant was them issued against the shipment for alleged violatin of Section 118 (g), 119 (d), and 1113 par. f, I, and l (3 and 4) of R.A. No. 10863 or the Customs Modernization and Tariff Act (CMTA) in relation to R.A. No. 9165.

    District Collector Austria praised the personnel for fulfilling the BOC’s mandate to curb the spread of drugs during the holiday season.

    The BOC, under the guidance of Commissioner Bienvenido Rubio, stood firm in its campaign against illegal drugs smuggling based on the orders of President Ferdinand Marcos Jr.

    “The Bureau of Customs pledges to prevent smuggling and protect the country’s borders and our citizens’ well-being against the dangers of illegal drugs,” Rubio said.

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  • Customs officers seize over $380,000 worth of cocaine off bus from Mexico | CNN

    Customs officers seize over $380,000 worth of cocaine off bus from Mexico | CNN

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    CNN
     — 

    US customs officers in Texas discovered nearly two dozen packages of cocaine on a commercial bus coming from Mexico.

    Field operations officers with the US Customs and Border Protection seized the “significant amount” of narcotics at the Roma International Bridge in Roma, Texas, the agency reported. Roma is along the Rio Grande in South Texas, roughly 50 miles northwest of McAllen.

    Officers came across the drugs on August 12, according to a news release Tuesday. After the bus arrived, officers conducted a canine and non-intrusive inspection.

    The examination uncovered 22 packages that contained nearly 50 pounds of cocaine, the agency said.

    The seized narcotics had a street value of more than $380,000, CBP said.

    The agency has seized more than 65,000 pounds of cocaine since October 2022, CBP data shows.

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  • Biden administration declares fentanyl laced with xylazine ‘an emerging threat’ in the US | CNN

    Biden administration declares fentanyl laced with xylazine ‘an emerging threat’ in the US | CNN

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    CNN
     — 

    The White House has declared that the powerful synthetic opioid fentanyl combined with xylazine – an animal tranquilizer that’s increasingly being used in illicit drugs – is an “emerging threat” facing the United States due to its role in the ongoing opioid crisis.

    Administration officials call the threat FAAX, for fentanyl-adulterated or -associated xylazine.

    The move, announced Wednesday, marks the first time in history that any administration has declared a substance to be an emerging threat to the country, said Dr. Rahul Gupta, director of the Office of National Drug Control Policy. The SUPPORT Act of 2018 established that the office has authority to declare such “emerging threats,” and no administration has used it until now. Last year, Congress declared methamphetamine an emerging drug threat but none have been declared by an administration previously. Under other agencies or in separate circumstances, concerns such as bioterrorism, infectious diseases or climate change may be identified as “emerging threats.”

    “This drug, which is an animal sedative, is being mixed with fentanyl and is being found in almost all 50 states now,” Gupta said Tuesday. “It’s become an important part for us to make sure that we’re declaring it an emerging threat.”

    Now that the administration has declared fentanyl combined with xylazine an emerging threat, it has 90 days to coordinate a national response. “We are working quickly to develop and implement a whole of government nationwide plan, with real deliverable action, that will save lives and will be published within 90 days of this designation,” Gupta said.

    Xylazine, also known as tranq or tranq dope, has been linked to an increasing number of overdose deaths in the United States due to its rising illicit use. Between 2020 and 2021, overdose deaths involving xylazine increased more than 1,000% in the South, 750% in the West and about 500% in the Midwest, according to an intelligence report released last year by the US Drug Enforcement Administration.

    And in some cases, people might not even know that xylazine was in the drug they used.

    Just last month, authorities at the DEA issued a public safety alert about the “widespread threat” of fentanyl mixed with xylazine, reporting that in 2022 approximately 23% of fentanyl powder and 7% of fentanyl pills seized by the DEA contained xylazine.

    Fentanyl, which has been driving the opioid crisis, is a fast-acting opioid, and people who use it illicitly say that adding xylazine can extend the duration of the high the drug provides.

    Xylazine is not an opioid. It is approved by the US Food and Drug Administration for use as a tranquilizer in veterinary medicine, typically in horses, but it is not approved for use in humans. And xylazine can do major damage to the human body, including leaving drug users with severe skin ulcers, soft-tissue wounds and necrosis – sometimes described as rotting skin – that can lead to amputation.

    “Xylazine is one of the contaminants in fentanyl, but there could be others,” Gupta said. “So, I think with the declaration of an emerging threat, we’re sending a clear message to producers and traffickers of illicit xylazine and illicit fentanyl that we’re going to respond quicker, we’re going to match the challenge of evolution of these drugs supply, and that we’re going to protect lives first and foremost.”

    Now that xylazine has been declared an emerging threat, some of President Biden’s $46 billion drug budget request to Congress can be used to respond.

    This year, the Biden administration announced that the President has called on Congress to invest $46.1 billion for agencies overseen by the Office of National Drug Control Policy to tackle the nation’s illicit drug crisis.

    If the budget request is not approved, there could be the option to reallocate money within the Office of National Drug Control Policy, but “we don’t want to be in a position where moneys that are being utilized for some other important aspect of saving lives has to be moved away for this purpose,” Gupta said Tuesday. “That is the reason we are asking Congress to act.”

    Such funds could be used to test drugs on the street for xylazine, collect data on FAAX, invest in care for people exposed to FAAX and develop potential treatments for a xylazine-related overdose.

    The medication naloxone, also known as Narcan, is an antidote for an opioid overdose, but people who have overdosed on a combination of opioids and xylazine may not immediately wake up after taking naloxone, as it may not reverse the effects of xylazine in the same way it does opioids.

    “We need to recognize, first of all, that there is a shift that is occurring from organic compounds and substances like heroin and cocaine to more synthetics,” Gupta said of the state of the nation’s illicit drug crisis.

    “Both the types of drugs have changed – from predominantly organic to predominantly synthetics – but the way drugs are bought and sold have also changed,” he said. “Now, all you need is a phone in the palm of your hand and a social media app to order and buy some of the most dangerous substances on planet Earth.”

    Xylazine is just one of the many adulterants – or substances that are typically added to others – found in the nation’s illicit drug supply.

    “All of a sudden, you can synthesize hundreds of compounds and kind of mix them together and see what does the best in the market,” Joseph Friedman, a researcher at the University of California, Los Angeles, told CNN in March. “People are synthesizing new benzodiazepines, new stimulants, new cannabinoids constantly and adding them into the drug supply. So people have no idea what they’re buying and what they’re consuming.”

    Some of these adulterants may be as simple as sugar or artificial sweeteners added for taste or additives or fillers that bulk up the drug. Sometimes, they may be contaminants left over from the manufacturing process.

    But all of these things can carry real-life health harms, says Naburan Dasgupta, an epidemiologist and senior scientist at the Gillings School of Global Public Health at the University of North Carolina, Chapel Hill.

    Like an opioid, xylazine can depress the respiratory system, so the risk of overdose multiplies when it’s combined with heroin or fentanyl.

    Also, “in the veterinary literature, we know that it causes a really bad severe form of anemia. And so when people are injecting heroin that’s contaminated with xylazine, they can end up with a near-fatal form of blood iron deficiency,” Dasgupta said in March. “We had one person here who ended up going to the hospital needing multiple blood transfusions. And it was all because of the xylazine.”

    US lawmakers are moving to classify xylazine as a controlled substance.

    In March, bipartisan legislation – the Combating Illicit Xylazine Act – was introduced in the House and Senate. It describes illicit xylazine as an “urgent threat to public health and safety” and calls for it to be a Schedule III drug under the Controlled Substances Act, a category on the five-level system for substances with moderate to low potential for physical or psychological dependence. Xylazine would be one level below opioids like fentanyl.

    “Our bipartisan bill would take important steps to combat the abuse of xylazine by giving law enforcement more authority to crack down on the illicit distribution of this drug, including by putting stiffer penalties on criminals who are spreading this drug to our communities,” Sen. Maggie Hassan, D-N.H., said in a statement in March.

    The bill would also require manufacturers to send reports on production and distribution to the DEA so the agency can ensure that the product is not being diverted to the black market.

    “This bill recognizes the dangers posed by the increasing abuse of animal tranquilizers by drug traffickers, and provides new tools to combat this deadly trend,” Sen. Chuck Grassley, R-Iowa, said in the statement.

    “It also ensures that folks like veterinarians, ranchers and cattlemen can continue to access these drugs for bona fide animal treatment.”

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  • The US sanctioned Chinese companies to fight illicit fentanyl. But the drug’s ingredients keep coming | CNN

    The US sanctioned Chinese companies to fight illicit fentanyl. But the drug’s ingredients keep coming | CNN

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    CNN
     — 

    The seller, who went by the name Linda Wang, was curt when asked if she sold a chemical often used to create fentanyl.

    “That’s banned,” Wang replied, before quickly providing an alternative: “CAS79099 powder is best. U can have a try.” 

    After more than a week of back and forth, she seemed impatient. “Ok. 79099 powder in USA warehouse now…if you need. Pls order asap,” she wrote in a text message exchange.

    The interaction is part of a CNN investigation that explored whether US-sanctioned chemical companies in China are evading Washington DC’s crackdown on illicitly made fentanyl – finding at least one China-based company that had links to a sanctioned entity, and a seller eager to ship potential ingredients for the lethal drug.

    More than 100,000 Americans died from drug overdoses in 2021, and two-thirds of the fatalities involved synthetic opioids – much of it believed from illicitly made fentanyl, according to the Centers for Disease Control.

    The drug can be 50 times stronger than heroin and 100 times stronger than morphine – and pharmaceutical grade versions of it can be prescribed by doctors for severe pain. But illegally manufactured fentanyl has turbocharged the US’s opioid overdose crisis in the last decade, according to data from the CDC.

    Controlling the illegal trade of the drug has turned into a geopolitical headache for the Biden administration, as China’s vast chemicals market – which supplies the world with raw materials for everything from perfume to explosives– is also a major pipeline of the building blocks of fentanyl, known as fentanyl precursors, according to US officials. 

    Further complicating the fight against fentanyl is the sheer variety of precursors that can be used to make fentanyl and other illicit drugs. Most such precursors also have legitimate uses – including for medical research – and are perfectly legal to sell, making up part of the booming transnational trade.

    China has strict anti-drug policies domestically, but critics in the US say it is not doing enough to help monitor or regulate purchases from buyers aiming to use Chinese-made ingredients to manufacture illegal drugs overseas.

    In 2019, Beijing stepped up its crack down on the production and sale of finished fentanyl and its variants, but US-China anti-drug cooperation has since stalled amid disagreements on trade, human rights, the Covid-19 outbreak and Taiwan. Hopes that US Secretary of State Antony Blinken would bring up fentanyl during a planned visit to Beijing died in early February, when Blinken postponed his trip after a surveillance balloon from China floated over the continental US. 

    As the opioid crisis topped the domestic agenda in 2021, the US sanctioned four companies in China accused of exporting fentanyl or fentanyl precursor chemicals. Online commercial records suggest ties between one of those sanctioned companies, Hebei Atun Trading Co., Ltd., and another China-based company called Shanxi Naipu Import and Export Co., Ltd., that continues to sell fentanyl precursors legally.

    According to official public records in China, Hebei Atun Trading Co., Ltd., began liquidating in June 2021 and was formally dissolved in August that year. Shanxi Naipu Import and Export Co., Ltd. was registered in the same period, according to official records, and it shares a number of key things in common with Hebei Atun.

    For example, Hebei Atun’s still-active Facebook page once linked to a now-defunct website of Shanxi Naipu – which is where CNN found Wang’s phone number.

    The two companies’ websites are registered to the same email address, and at one time appeared to share an IP address. Today, Shanxi Naipu’s websites appear to be carbon copies of Hebei Atun’s since-deleted page – with the same navigation tabs, email address and stock photo of a pipette dropping amber-colored liquid into a cell tray. The Russian and Portuguese versions of the site list “Hebei Atun Trading Co. Ltd.” as their copyright holder.

    One post on a Shanxi Naipu website was titled, “Hebei ATUN Trading Co., Ltd. Wishes you a Happy New Year!” (sic). It has since been deleted. 

    When presented with CNN’s findings, Shanxi Naipu denied ties to Hebei Atun, saying, “we are not related at all.” In statements emailed to CNN, Shanxi Naipu said it had purchased the sanctioned company’s Facebook account, email and cell phone number in order to “attract internet traffic.”

    Shanxi Naipu also denied selling the fentanyl precursor that Wang offered by text, and stressed that everything they sell is legal, and said that they were taking steps to stop the repercussions from the apparent links to Hebei Atun.

    “To prevent further impact from Hebei Atun, we have immediately removed relevant promotional websites and platforms,” the company said in an emailed statement.”

    Logan Pauley, a China analyst who tracks criminal and drug networks, told CNN, “It’s easy on the Chinese side to start a new company to copy and paste the same text that you’re posting on social media or you’re posting on a trade website, and then just to recreate the same operation over and over again.”

    And Gary Hufbauer, trade expert at the Peterson Institute for International Economics and former US treasury official, likens it to a game of cat-and-mouse. While the US government can add an entity to its sanctions list “overnight,” said Hufbauer, there may not be the resources in the US Treasury’s Office of Foreign Assets Control, which enforces sanctions, to keep tabs on new companies that may leverage sanctioned companies’ branding or operations. 

    In a statement to CNN, a spokesperson for the US Treasury said it “had not hesitated” to go after “bad actors” – citing the four sanctioned Chinese companies – and would continue to sanction companies and individuals involved in the drug trade.

    “Treasury continues to monitor the effects of our designations,” they said. “If additional information becomes available that can assist sanctions compliance efforts, when appropriate, we provide that information to industry and/or the public.”

    Asked if Beijing was knowingly lax in its efforts to stem the flow of precursor chemicals from its country, the Chinese Foreign Ministry pointed out that most were not controlled substances, in a lengthy statement that also questioned US efforts to treat addiction and demand for opioids.

    “China has always strictly controlled precursor chemicals in accordance with international conventions and domestic laws. The US side’s so-called ‘fentanyl precursors,’ a small number of them are listed substances by the United Nations, and China has always been resolute in implementing the listed measures. But most of the rest are common chemicals that are not listed by the United Nations, China or even the United States itself,” it said in a written statement to CNN.

    “Government departments do not have the right or the possibility to regulate non-listed chemicals and common commodities,” it added.

    The ministry statement went on to highlight China’s harsh domestic penalties on drug trade and consumption. “The Chinese people deeply resent drugs. the Opium War was the beginning of China’s modern history of humiliation. The Chinese government has always cracked down on drug crime, and China is a no-go area for international drug dealers.”

     Such unregulated precursors, like the one offered by Wang, are not illegal to sell but can be used in the manufacture of illicit substances like fentanyl, methamphetamine, and cocaine.

    Several precursors used to create fentanyl have been put under international control since 2017, but a savvy chemical engineer can combine legal precursors further up the synthesis chain to make similar compounds.

    “What we have seen illicit chemists doing now is that certain components of the synthesis are now … harder for them to purchase, so what they’re doing now is they’re buying compounds that are structurally very, very similar,” Alexandra Evans, a forensic chemist with the D.C. Department of Forensic Sciences, told CNN from her lab in the US capital.

    Or they can create fentanyl analogues, substitutes that are chemically similar to fentanyl and which has made the crisis more deadly in recent years. One fentanyl analogue was found to be 10,000 times stronger than morphine, according to a 2021 US government report.

    Controlling the stream of chemicals has turned into a deadly game of whack-a-mole – where manufacturers are able to use a variety of precursors to synthesize fentanyl and its analogues faster than either can be identified, banned, or regulated. 

    Many of the building blocks to fentanyl have benign purposes and are legal to buy, but a menu Wang sent of Shanxi Naipu’s chemical products for sale appeared designed to support illegal drug manufacture, according to a synthetic chemist who analyzed the list for CNN. 

    It was “obviously a list curated to help people create illicit drugs,” Lyle Isaacs, a professor in the Department of Chemistry and Biochemistry at the University of Maryland, told CNN of the more than 25 chemical compounds on the menu. 

    At least three compounds on the list could be made into fentanyl, he said. One of the compounds, CAS 79099-07-3, also known as 1-Boc-4-piperidone, was what Wang offered to sell CNN; the other two compounds also have legitimate uses and can be found, for example, in academic laboratories researching future medicines, Isaacs said. 

    Still more compounds on the list appeared to be building blocks for meth, ecstasy, ketamine, and the cutting of cocaine, as well as over-the-counter drugs like paracetamol, a common pain medication that can also be used to cut heroin and other narcotics, he added. 

    Asked about the list, Shanxi Naipu reiterated in its statement to CNN that all products on it are legal in China, stating: “We are not professional chemists but just a trading company. Even though we don’t have an intimate knowledge of the composition and use of thousands of chemicals, we have always strictly ensured the legality of our products!”

    Attempts to contact Wang through the company for comment were not successful, and the company said in its statement that she no longer works for them.

    There are measures that responsible chemical sellers can take to avoid their products being used for illegal drugs.

    Identity checks are a hallmark of reputable sellers, said a former Drug Enforcement Administration (DEA) official. The source spoke to CNN on the condition of anonymity because they were not authorized to speak to the media. To sell non-listed chemicals, a good-faith seller would normally ask a buyer about the intended use of the compound, and whether the buyer had the backing of a company or institution, such as a research organization or university.  

    American buyers of regulated chemicals require licenses from the DEA, depending on how hazardous they are. Reputable sellers may also ask for tax identifications even for chemicals that are not controlled, like precursor materials, the source said.

    At no point in the conversation was Wang aware, nor did she ask for the identities of the CNN reporters speaking to her or what CNN planned on using it for. She even offered a “door to door” precursor delivery service via warehouses in the US or Mexico – locations that CNN has been unable to verify.

    In its statement to CNN, Shanxi Naipu denied that it had warehouses in either country.

    The small quantity of precursor needed to manufacture fentanyl ultimately makes shipments destined for illicit ends hard to catch at the border, points out Martin Raithelhuber, an illicit synthetic drugs expert at the United Nations Office on Drugs and Crime.

    “You have hundreds of thousands of tonnes (of chemicals in a shipment), and you are looking for a few kilograms, which are sufficient to produce a supply of millions of doses (of fentanyl),” he said. 

    Since China banned the production of fentanyl and related substances in 2019, Mexican criminal organizations have largely taken control of the drug’s production and sale, smuggling finished fentanyl to consumers in the US, according to a 2022 report from the Congressional Research Service.

    Mexico is now the source of “the vast majority” of meth, heroin and illicit fentanyl seized in the US, according to the US International Narcotics Control Strategy Report (INCSR) released in March 2023. “In 2022, the United States identified Mexico as the sole significant source of illicit fentanyl and fentanyl analogues significantly affecting the United States,” it reads.

    “Criminal elements, mostly in the People’s Republic of China, ship precursor chemicals to Mexico, where they are used to produce illicit fentanyl,” Dr. Rahul Gupta, director of the White House’s Office of National Drug Control Policy, told the Senate Foreign Relations Committee earlier this year. 

    “The only limit on how much fentanyl they can make is the amount of precursor chemicals they can get,” DEA Administrator Anne Milgram told CNN in early March.

    The Biden administration has taken aim at these groups and in February sanctioned a network of Sinaloa Cartel members and associated entities for their involvement in the fentanyl and methamphetamine trade. 

    Mexico’s law enforcement has also fought the trade, seizing and impounding hundreds of kilos of fentanyl precursors and pills – including a cache of over a million potential fentanyl pills in the Mexican border city of Tijuana on March 13.

    Ultimately, tackling fentanyl requires close coordination between the US, Mexico, and China. Even if countries like Mexico had the best national control measures, international cooperation is needed to understand “which flows are the ones we need to watch or [be] worried about,” Raithelhuber said.

    Former DEA official Matthew Donahue told CNN he would like to see Mexico do more, including cracking down on properties and other assets of those involved in the drug trade.

    But as the US pressures other governments to help slow the flow of illicit fentanyl, relations between the three countries have turned into a three-way blame game.

    Following the kidnapping of four Americans in a Mexican border town by cartel members in early March, US Republicans called for the US military to be allowed to fight cartels and destroy drug labs in Mexico – something Mexican President Andrés Manuel López Obrador called “an offense to the people of Mexico.” 

    “We are not a protectorate of the United States or a colony of the United States. Mexico is a free, independent, sovereign country. We don’t take orders from anyone,” López Obrador said at a news conference on March 9. 

    Washington has also called on Beijing to do more, with the latest US INCSR report describing China’s oversight functions as “poorly staffed and under-resourced to oversee its massive chemical industry.” Though it acknowledges Beijing’s harsh penalties for drug trafficking, the report laments ineffective controls on shipment labeling, customer vetting and pill-making equipment.

    The Ministry of Foreign Affairs’ statement to CNN emphasizes its “stringent” control of listed chemicals that could be used for drug-making and argues that Beijing has “improved” several “regulatory mechanisms such as end-user verification, leakage monitoring, and source backtracking, and has strengthened management of more than 200,000 chemical companies.”

    Both China and Mexico have called on the US to do some soul-searching about demand for illicit fentanyl.

    “US legislators and the authorities there are not doing their job because they are not addressing the causes (of addiction); there are no care programs for young people in the US,” López-Obrador said last week.

    “Using China as a scapegoat will not solve the drug crisis in the United States … ,” the Chinese Foreign Ministry’s statement to CNN read. “We advise the US side to reflect on itself, stop shifting blame, strengthen domestic prescription drug control, enhance publicity on the dangers of drugs, and take practical measures to reduce domestic drug demand.”

    Prescription opioids like oxycodone and hydrocodone – which have a similar chemical structure to heroin and fentanyl – were major contributors to the early opioid crisis in the US. Pharmaceutical giants, notably Purdue Pharma, downplayed the potentially addictive properties of the drugs and incentivized US doctors to prescribe the painkillers. But prescribing was curtailed as overdoses from prescription opioids climbed and now waves of heroin and illicit fentanyl took over, making the crisis far more deadly. 

    Amid the recriminations, fentanyl products continue to pour through US borders and Americans continue to die. 

    To raise awareness of the human toll, the US Drug Enforcement Administration last year created “The Faces of Fentanyl” exhibit at its headquarters in Arlington, Virginia where families can submit a photo of a loved one lost to the fentanyl crisis. So far more than 5,000 photos have been submitted.

    “We can’t be desensitized” to the number of lives lost to drug overdoses,” Donahue, the former DEA official, said. “The pain and suffering that these families are going through. That has got to mean something.” 

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  • Colombia plans to send 70 ‘cocaine hippos’ to India and Mexico, governor says | CNN

    Colombia plans to send 70 ‘cocaine hippos’ to India and Mexico, governor says | CNN

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    CNN
     — 

    Colombia plans to fly dozens of its “cocaine hippos” – the descendents of drug trafficker Pablo Escobar’s private menagerie – to new homes in India and Mexico in a bid to control their booming population, according to the local governor.

    There are now between 130 and 160 of the hippos, according to the Colombian government, and they have spread out far beyond Escobar’s former ranch of Hacienda Napoles, where they began as a population of just one male and three females.

    The original hippos were part of a collection of exotic animals Escobar had amassed in the 1980s at his ranch about 250 kilometers (155 miles) from Medellín. After his death in 1993, authorities relocated most of the other animals, but not the hippos – because they were too difficult to transport.

    But they have since begun to reproduce rapidly, extending their reach along the Magdalena River basin, and they now pose an environmental challenge and are concerning nearby residents, authorities say.

    A study in the journal Nature warned their numbers could balloon to 1,500 within two decades.

    Previously, authorities have tried to control their population using castrations and “shots” of contraceptive darts. But the contraceptive drives have had limited success.

    Now there’s a plan to transfer 70 of the hippos to natural sanctuaries in India and Mexico, the governor of Antioquia province, where Hacienda Napoles is located, said in a Tweet.

    A total of 70 hippos, a mix of males and females, are expected to be moved – with 60 going to India and 10 to Mexico.

    The technical term for this operation is “translocating,” governor Aníbal Gaviria explained in an interview with the Colombian outlet Blu Radio, as it would involve moving the hippos from one country that was not their native habitat to another that was also not their natural habitat.

    The goal was “to take them to countries where these institutions have the capacity to receive them, and to (home) them properly and to control their reproduction,” Gaviria said.

    Sending the hippos back to their native land of Africa was “not allowed,” Gaviria said.

    Sending the hippos back to Africa risked doing more harm than good, for both the hippos themselves and the local ecosystem, María Ángela Echeverry, professor of Biology at the Javeriana University, previously explained to CNN.

    “Every time we move animals or plants from one place to the other, we also move their pathogens, their bacteria and their viruses. And we could be bringing new diseases to Africa, not just for the hippos that are out there in the wild, but new diseases for the entire African ecosystem that hasn’t evolved with that type of disease,” Echeverry said.

    Aside from reducing the number of hippos in Colombia, authorities are hoping to learn how to manage the remaining population, which are recognized as a potential tourist attraction.

    The hippos will be flown in purpose-built boxes, Gaviria said in the radio interview, and will not be sedated at first.

    But “emergency sedation” is possible if one of the animals is overcome by nerves during the flight, he added.

    The translocation could be completed by the first half of this year if necessary permits are expedited, especially from the Colombian Agricultural Institute, Gaviria said.

    Hippos are seen by some as an invasive species that can pose a danger to local ecosystems and sometimes even to humans.

    Research has highlighted the negative effects hippo waste can have on oxygen levels in bodies of water, which can affect fish and ultimately humans.

    Nature magazine cited a 2019 paper that found lakes where hippos were present had more cyanobacteria, which are associated with toxic algae. These blooms can reduce water quality and cause mass fish deaths, affecting local fishing communities.

    Hippos can also pose a threat to agriculture and to people’s safety, according to a Biological Conservation study published in 2021. Hippos can eat or damage crops and engage in aggressive interactions with humans.

    “Hippos live in herds, they are quite aggressive. They are very territorial and are plant eaters in general,” said Professor Echeverry.

    While the “cocaine hippos” are not native to Colombia, the local terrain is thought to be favorable for their reproduction, since it has shallow water sources and a large concentration of food.

    Until now, Colombia has not been able to solve a problem that – in the words of Gaviria to Blu Radio – “got out of control.”

    Whether the latest efforts will succeed where birth control efforts failed remains to be seen.

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  • More than 4.5 million fentanyl pills, 3,000 pounds of methamphetamine seized in Arizona investigation, DEA says | CNN

    More than 4.5 million fentanyl pills, 3,000 pounds of methamphetamine seized in Arizona investigation, DEA says | CNN

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    CNN
     — 

    Arizona authorities targeting the Sinaloa drug cartel have seized narcotics estimated to be worth more than $13 million, including more than 4.5 million fentanyl pills, 3,100 pounds of methamphetamine and large quantities of heroin, cocaine and fentanyl powder, according to the Drug Enforcement Administration.

    In a news release, the agency said the seizure was the culmination of a three-year-long investigation during which 150 people had so far been charged.

    “The fentanyl seized represents more than 30 million potentially lethal doses,” the DEA said, announcing the seizure in partnership with the Tempe Police Department and Arizona Attorney General Kris Mayes.

    Authorities displayed some of the recovered narcotics at a joint news conference Thursday, attended by CNN affiliate KNXV.

    “The sample you see here today is staggering. There are over 4.5 million fentanyl pills, over 140 pounds of fentanyl powder, over 135 kilos of cocaine, over 3,000 pounds of methamphetamine, 35 kilos of heroin, 49 firearms and over $2 million in cash,” Interim Tempe Police Chief Josie Montenegro told reporters.

    Montenegro said the substances recovered “would be poisoning members of our community, including our youth and vulnerable population,” had the seizures not been made.

    “In addition, the dangers and crimes associated with illegal drugs would be plaguing our community,” Montenegro added.

    According to authorities, “numerous” people were taken into custody in the bust. At this time, authorities do not plan on releasing the names of those involved because it is a continuing investigation, according to Montenegro.

    Phoenix DEA Special Agent in Charge Cheri Oz said investigators are “laser-focused” on the Sinaloa cartel.

    “I want to be crystal clear, the drugs in this room and the drugs that are flooding Arizona every single day are sourced primarily by one evil as the Sinaloa drug cartel,” she said at the news conference. “We are laser-focused on the Sinaloa drug cartel and we will defeat them. We will not stop.”

    Oz also praised the efforts of DEA agents and other officers over the last three years. “Their hard work and tenacity is responsible for removing these deadly drugs before they poisoned our family, our friends and our neighborhoods,” she said.

    The country is struggling with a decades-long opioid epidemic in which fentanyl has become the most commonly used drug involved in overdoses.

    Pharmaceutical fentanyl is a synthetic opioid intended to help patients manage severe pain. It is 50 to 100 times more potent than morphine, and typically prescribed in the form of skin patches or lozenges. But most recent cases of fentanyl-related harm, overdose, and death in the United States are linked to illegally made fentanyl, according to the US Centers for Disease Control and Prevention.

    Deaths involving synthetic opioids increased by 22% in 2021, according to CDC data, and in 2022, there were about 181,806 nonfatal opioid overdoses recorded in the United States.

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  • What to know about the lawsuit aiming to ban medication abortion drug mifepristone | CNN Politics

    What to know about the lawsuit aiming to ban medication abortion drug mifepristone | CNN Politics

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    CNN
     — 

    A federal judge may rule later this month on a lawsuit seeking to block the use of medication abortion nationwide, in the biggest abortion-related case since the Supreme Court overturned Roe v. Wade last year.

    The lawsuit, filed in November by anti-abortion advocates against the US Food and Drug Administration, targets the agency’s 20-year-old approval of mifepristone, the first drug in the medication abortion process

    Medication abortion, which now makes up a majority of abortions obtained in the US, has become a particularly acute flashpoint in the fallout from the Supreme Court’s decision last year overturning Roe v. Wade.

    US District Judge Matthew Kacsmaryk, an appointee of former President Donald Trump, has extended the briefing deadline in the case until February 24.

    Reproductive rights advocates say that if Kacsmaryk sides with the plaintiffs, “it would eliminate the most commonly used method of abortion care,” according to NARAL Pro-Choice America.

    Here’s what to know about the lawsuit:

    The lawsuit, filed last year by a coalition of anti-abortion national medical associations under the umbrella of the “Alliance for Hippocratic Medicine” and several doctors, is seeking a number of actions by the court, chief among them a preliminary and permanent injunction ordering the FDA “to withdraw mifepristone and misoprostol as FDA-approved chemical abortion drugs and to withdraw defendants’ actions to deregulate these chemical abortion drugs.”

    “After two decades of engaging the FDA to no avail, plaintiffs now ask this court to do what the FDA was and is legally required to do: protect women and girls by holding unlawful, setting aside, and vacating the FDA’s actions to approve chemical abortion drugs and eviscerate crucial safeguards for those who undergo this dangerous drug regimen,” the complaint reads.

    The FDA responded to the lawsuit last month by asking the judge to deny the motion for a preliminary injunction, arguing that issuing one in the matter “would upend the status quo and the reliance interests of patients and doctors who depend on mifepristone, as well as businesses involved with mifepristone distribution.”

    The agency also says a ruling against it would set a dangerous precedent.

    “More generally, if longstanding FDA drug approvals were so easily enjoined, even decades after being issued, pharmaceutical companies would be unable to confidently rely on FDA approval decisions to develop the pharmaceutical-drug infrastructure that Americans depend on to treat a variety of health conditions,” the FDA wrote.

    “A preliminary injunction would interfere with Congress’s decision to entrust FDA with responsibility to ensure the safety and efficacy of drugs. In discharging this role, FDA applies its technical expertise to make complex scientific determinations about drugs’ safety and efficacy, and these determinations are entitled to substantial deference.”

    Danco, which makes mifepristone, also made a similar request to the FDA’s in a court filing, stressing that the lawsuit could decimate the company’s business.

    “Danco is a small pharmaceutical company. It sells one drug: Mifeprex,” lawyers for the company wrote in court papers. “Entering the mandatory preliminary injunction plaintiffs seek would force FDA to withdraw approval for Danco’s only product, effectively shuttering Danco’s business.”

    “Congress entrusts decision-making like this with the FDA. And they’re coming in trying to overrule that, saying this medication is unsafe because women bleed. Well, that’s part of having an abortion. It’s also part of having a pregnancy,” said Ryan Brown, an attorney representing Danco in the case. “The bottom line being that they just want to do away with abortion across the board and for any reason.”

    Kacsmaryk was appointed to the court in 2017 by then-President Trump and was confirmed by a 52-46 vote in 2019.

    Since then, he’s helped make Texas a legal graveyard for policies of President Joe Biden’s administration, presiding over 95% of the civil cases brought in Amarillo, Texas.

    In December, Kacsmaryk put on hold the Biden administration’s most recent attempt to end the so-called “Remain in Mexico” program. And he has overseen Texas cases challenging vaccine mandates, the gender identity guidance issued by the US Equal Employment Opportunity Commission and the administration’s limits on the use of Covid-19 relief funds for tax cuts.

    Before joining the court, Kacsmaryk served as deputy general counsel at the First Liberty Institute, a nonprofit religious liberty legal group, where he worked mainly on “religious liberty litigation in federal courts and amicus briefs in the US Supreme Court,” according to his White House biography.

    The case is being closely watched by a number of interested parties, including Republican and Democratic state attorneys general. On Friday, two different multi-state coalitions filed amicus briefs with the court urging them to act one way or another in the matter.

    A coalition of 22 Democratic attorneys general urged Kacsmaryk to deny the motion for a preliminary injunction, writing in court papers that “annulling – or even merely limiting – any of the FDA’s actions relating to medication abortion would result in an even more drastic reduction in abortion access across the entire nation, worsening already dire outcomes, deepening entrenched disparities in access to health care, and placing a potentially unbearable strain on the health care system as a whole.”

    And a coalition of 22 Republican attorneys general asked the court to issue the preliminary injunction, arguing the FDA exceeded its authority when it approved the medication.

    “State laws on chemical abortion thus account for the public interests at issue – and they do so with the benefit of democratic legitimacy (and legal authority). The FDA’s actions can make no such claim. By obstructing the judgments of elected representatives, the agency has undermined the public interest,” they wrote.

    Abortion rights advocates have sounded the alarm on the case, stressing that a ruling by Kacsmaryk in favor of the plaintiffs would affect every corner of the country since the lawsuit is targeting a federal agency.

    “If FDA approval of mifepristone is revoked, 64.5 million women of reproductive age in the US would lose access to medication abortion care, an exponential increase in harm overnight,” NARAL said in a statement on Friday, pointing to internal research.

    “This research reveals the high stakes of this lawsuit, and we can only expect the worst from this Trump-appointed federal judge. Americans want access to abortion, but anti-choice bad actors are dead set on restricting reproductive freedom by any means possible,” said Angela Vasquez-Giroux, the group’s vice president of communications and research.

    And activists are mobilizing in Texas around the issue, with the Women’s March planning to hold a rally at the federal courthouse in Amarillo, Texas, on Saturday.

    “We’ve said it before: the fight for reproductive rights now lies in the states, and legal challenges like these are just the latest example of how our fight is bigger than Roe,” said Rachel Carmona, the executive director of Women’s March.

    On Thursday, Kacsmaryk told the plaintiffs that they had until February 24 to respond to a recent filing by the Danco, writing in an order that following the deadline, “briefing will then be closed on the matter, absent any ‘exceptional or extraordinary circumstances.’”

    On Friday, the plaintiffs in the case submitted one response to the FDA’s filing. But the deadline extension means that after the plaintiffs submit a separate response to Danco, the case is ripe for judgment since all required briefings will have been filed.

    Kacsmaryk can rule at any time after that, though he could also call for a hearing, or ask for additional responses as well.

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  • Elizabeth Banks knows risk of new movie ‘Cocaine Bear’ could come back and bite her | CNN

    Elizabeth Banks knows risk of new movie ‘Cocaine Bear’ could come back and bite her | CNN

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    CNN
     — 

    With her bonkers new movie “Cocaine Bear,” Elizabeth Banks knew she wanted “to make something muscular and masculine.”

    In a new interview with Variety published on Wednesday, Banks – who directed and coproduced the film about a drug-fueled bear on a killing rampage – shared how difficult it was to convince some Hollywood power players that a woman could helm such a movie.

    “I wanted to break down some of the mythology around what kinds of movies women are interested in making,” Banks said. “For some bizarre reason, there are still executives in Hollywood who are like, ‘I don’t know if women can do technical stuff.’ There are literally people who are like, ‘Women don’t like math.’ It just persists.”

    She acknowledged that the new movie – which is based on a true story from the 1980s about a drug drop gone wrong that resulted in a bear ingesting cocaine – is “a ginormous risk,” adding that it “could be a career ender for me.”

    Part of the trepidation is the lackluster box office performance of original comedies, which has caused the industry to cool around the genre.

    But Banks is hopeful that the sheer zaniness of the concept – plus the bloody horror aspect of a cocaine-addled bear ripping people to shreds – will get people in the movie theater.

    “I love gore. I grew up on ‘Evil Dead,’” Banks told Variety. “The gore is part of the fun of the ride.”

    “Cocaine Bear” is set for release on February 24.

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  • Tracking the opioid crisis: Inside the DEA’s secret lab | CNN

    Tracking the opioid crisis: Inside the DEA’s secret lab | CNN

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    Watch CNN Films’ “American Pain” at 9 p.m. ET Sunday, February 5.



    CNN
     — 

    Sitting among the warehouses of Dulles, Virginia, is one of the US Drug Enforcement Administration’s forensic labs. It’s one of eight across the country where scientists analyze illegal drugs and try to stay ahead of what’s driving deadly overdoses.

    Starting in the late 1990s with overprescribing of prescription narcotics, the opioid epidemic has continued to plague the United States for decades. What has changed is the type of drugs that have killed more than half a million people during the past 20 years.

    CNN was granted rare access to the secret lab where the DEA tests seized illicit drugs to understand what’s coming next.

    “The market is constantly changing, so we are trying to do everything we can from a science base to keep up with that,” Scott Oulton, deputy assistant administrator of the DEA’s Office of Forensic Sciences, told CNN Chief Medical Correspondent Dr. Sanjay Gupta.

    Holding a white bag of fentanyl precursor powder – one of the chemicals used to make the opioid – Oulton explained that the illicitly made painkiller continues to be a dominant presence in the drugs officials are finding.

    “This kilogram can be converted into fentanyl to make approximately 800 grams,” he said. “So it doesn’t take that much material, it’s fairly cheap, it’s inexpensive to obtain.”

    Fentanyl is the deadliest drug in the United States, and it’s often found in combination with other illicit drugs, including cocaine and heroin. But increasingly, fentanyl is showing up in illicit pills disguised as common prescription drugs like oxycodone, hydrocodone, even Adderall.

    Users buying drugs on the street that look like prescription pills may end up with a highly potent, potentially deadly drug they never intended to take.

    “Over 99% of what we see are fake. They contain fentanyl,” Oulton says of the pills that the agency is seizing.

    The 800 grams of fentanyl that Oulton held could be turned into 400,000 to 500,000 potentially lethal pills.

    As more and more of these lethal pills circulate, the opioid epidemic is reaching more of the population.

    Deena Loudon of Olney, Maryland, is among those living with its effects.

    “I truly love sharing Matthew with the world,” Loudon says as she flips through pictures of her son.

    One of her favorite memories is Matthew playing hockey – what Loudon calls his happy place.

    Matthew Loudon's mom says he turned to drugs after struggling with anxiety.

    But she also recalls his struggles with anxiety, which led him to turn to drugs. He started dabbling in them in the 10th grade. By the following year, his grades began to fall, and he couldn’t keep them high enough to stay in hockey.

    “He was using Xanax to help self-medicate himself and I think to help get rid of some of that angst so he could live somewhat of a normal life,” Loudon said.

    Matthew was always honest, almost to a fault, Loudon says. “He told me he tried everything. Like everything. Heroin, meth, crack, you name it, cocaine, whatever – until I guess he found what made him feel the best, and it was Xanax.”

    And as much as a mother can worry, Loudon says, Matthew always tried to reassure her. “I know what I’m doing,” he would tell her.

    She had heard about fentanyl showing up in pills in their area.

    “But you don’t ever think it’s going to happen to you,” Loudon said.

    She said they even had a conversation about fentanyl the day before he died. “I was sort of naive, wanting to stick my head in the sand and thinking ‘I bet he does know what he’s doing.’ ”

    On November 3, 2020, she found 21-year-old Matthew on the floor of their basement.

    Matthew’s autopsy report lists his cause of death as fentanyl and despropionyl fentanyl intoxication.

    “I don’t say he overdosed. I say he died from fentanyl poisoning. … Truthfully, like, at the end of the day, to me, he was murdered, right? Because he asked for one thing. They gave him something different. And it took his life.”

    For a parent, she said, the hardest thing is burying their child. It’s a pain she speaks out about in hopes of keeping other families safe.

    “It’s Russian roulette,” she warns them. “You never know what you’re gonna get.”

    The number of pills the DEA has seized skyrocketed in just three years, from 2.2 million in 2019 to 50.6 million in 2022.

    The sheer volume of pills has been one of the biggest challenges for the DEA’s lab, Oulton says. As the fentanyl threat continues to grow, the Virginia facility is expanding to accommodate the analysis needed.

    The lab can test for something as simple as the presence of fentanyl, but something called the purity of the pill also offers important insight. This means how much fentanyl is actually in one of these illicit pills.

    “Lately, we’ve been seeing a purity increase over the last year, where we used to say roughly four out of the 10 seizures that we were receiving would contain a lethal dose of greater than 2 milligrams. As of October last year, we started reporting that we’ve seen an uptick. Now we’re saying that six out of 10 of the seizures that we’re receiving contain over 2 milligrams,” Oulton said.

    He says they’re finding an average of 2.3 milligrams of fentanyl in each pill.

    Two milligrams may be the cutoff for what is considered lethal, but Oulton says that doesn’t necessarily mean a pill with 1.99 milligrams of fentanyl can’t be deadly.

    “One pill can kill” is his warning.

    “The message I would like to send out is, don’t take it,” he said. “Don’t take the chance. It’s not worth your life.”

    Oulton says he and his team are constantly finding new and different drugs and substances in pills – things they’ve never seen before.

    One machine in the lab is almost the equivalent of an MRI in a medical office, showing the structure and detail of a pill.

    “We will do what we call structural elucidation to determine that this is a different version of a fentanyl that’s got a new compound and molecule that’s been added to it,” Oulton said.

    They’ve seen “hundreds and hundreds of unique combinations,” he said.

    “We’ll see one that contains fentanyl, one with fentanyl and xylazine, one with fentanyl and caffeine, one with fentanyl and acetaminophen, and you don’t know what you’re getting.”

    Xylazine, a veterinary tranquilizer, poses a unique problem. It’s not an opioid, so even when it’s mixed with fentanyl, drugs designed to reverse an opioid overdose may not work.

    Narcan or naloxone, one of the more common overdose-reversing drugs, has become increasingly necessary as the prevalence and potency of illicit drugs increases. About 1.2 million doses of naloxone were dispensed by retail pharmacies in 2021, according to data published by the American Medical Association – nearly nine times more than were dispensed five years earlier.

    Oulton wants to be clear: The problem Isn’t with pills prescribed by your doctor and dispensed by a pharmacy – it’s the pills on the illicit market.

    Those, Matthew’s mother warns, are easy to get.

    “The first pills [Matthew] got was in high school. And it was just flipping out, floating around, and it was easy for him to get his hands on,” she said.

    Loudon’s message for parents now: Keep your eyes open.

    “Just be mindful of what your children are doing. You just just have to keep your eyes open. And even sometimes, when you keep your eyes open, you can miss some of the warning signs, but I think a parent knows their child best, so just keep talking.”

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  • CBP seizes $9.1 million worth of cocaine at the Pan American Dock in Puerto Rico | CNN

    CBP seizes $9.1 million worth of cocaine at the Pan American Dock in Puerto Rico | CNN

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    CNN
     — 

    US Customs and Border Protection officers seized 877 pounds of cocaine on board the San Juan-Santo Domingo Ferry at the Pan American Dock in Puerto Rico last month.

    The drugs, which have an estimated value of $9.1 million, were spotted on December 26 during a routine cargo inspection. Officers removed a board covering the floor of a cargo platform to reveal 355 packages that tested positive for cocaine, the CBP said in a statement.

    “Our experienced CBP officers remain vigilant, utilizing their training and available tools to stop dangerous drugs from entering the country,” Roberto Vaquero, director of field operation for Puerto Rico and the US Virgin Islands, said in the statement.

    Homeland Security Investigations took custody of the contraband for further investigation, according to the CBP.

    CBP has seized 77,000 pounds of drugs in the first two months of fiscal year 2023, according to the CBP Data Portal.

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