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  • The Hottest Startups in Berlin in 2024

    The Hottest Startups in Berlin in 2024

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    German innovation is not limited to the country’s capital. In fact, some of this year’s most prolific startups are based hundreds of miles away. The AI startup Alpha Alpha hails from Heidelberg. Helsing, which sells AI to Europe’s militaries, was set up in Munich. Yet both companies operate Berlin offices. The city attracts too much talent to ignore. Universities, such as TU Berlin, churn out Generative AI founders and the capital is such a magnet for international talent that many offices operate in English, not German.

    It’s also a very young city—half of its population is under 45, something that Thomas Dohmke, CEO of GitHub, who grew up in Berlin, remarks on. “I founded my last startup back in 2009 and I remember vividly how much energy, time, and focus it required—having a large population of younger, diverse and international, and highly motivated professionals that have that energy and hunger gives Berlin an edge,” he says. “Plus, Berlin has the best döner kebab.”

    BlueLayer

    By 2050, the carbon credit market is expected to be a $250 billion industry. Startup BlueLayer is catering to that growth by developing tailor-made software for the companies and NGOs poised to benefit. Its clients—including conservationists such as Permian Global—run projects ranging from reforestation to direct air capture, and use the startup’s software to process their data, and communicate with buyers and investors, while helping credit providers get their credits verified with international registries. Launched in 2022, BlueLayer has raised $10 million (€8.9 million) in investment and counts three of the top 10 issuers of credits globally among its clients. “It’s classic automation software,” says Vivian Bertseka, one of BlueLayer’s three co-founders along with Alexander Argyros and Gerardo Bonilla, “but for an industry that used to operate almost exclusively on Excel.” bluelayer.io

    Cambrium

    Cambrium, founded in 2020 by Mitchell Duffy and Charlie Cotton, is using AI to design proteins such as collagen. Instead of sourcing them from animal products, the startup grows them in tanks. “We’re one of the companies trying to straddle hardcore software engineering [and AI] with putting physical stuff in the real world,” says Cotton. The company has received $11.6 million (€10.3 million) in investment so far, including from Google’s AI venture fund Gradient Ventures. Skincare products using Cambrium’s first protein, a collagen called NovaColl, are expected to hit shelves later this year. Cambrium.bio

    Jina AI

    In 2020, three veterans of Chinese tech behemoth, Tencent, joined forces to build foundation models specifically for search. Attracted to Berlin by the city’s open source culture and software engineering talents, the trio behind Jina now claim 9,000 users and 400 paying customers, who turn to the company when they want to build either a public or internal search system for their data. Jina’s models promise to convert PDFs, Word documents or images into a language that AI models can understand well enough to enable an intuitive Google-style search. A legal company may no longer have to search for documents using a case number. Instead, Jina AI CEO and co-founder Han Xiao explains that they could simply ask: “Find the case where Microsoft loses to Google”. After raising $39 million (€34.8 million) from a series of early stage VC funds including Canaan Partners, Xiao and his co-founders Nan Wang and Bing He plan to expand to the US, raise revenue from the company’s $500,000 (€447,000) per year, and boost user numbers. “We want to compete with OpenAI,” says Xiao. jina.ai

    Han Xiao, cofounder of custom search-engine firm Jina AI.

    PHOTOGRAPH: THOMAS MEYER

    Endel

    Endel is a paid-for app that uses generative AI to create one endless piece of music, which constantly adapts to its user’s surroundings. The app utilizes the phone accelerometers to generate a beat that syncs with its listeners’ footsteps. If they start jogging or skipping, the tempo catches up. Calling itself a “sound wellness” startup, Endel is part of the trend for functional sound, where music has a purpose—to help people exercise, fall asleep or focus. “We want to create a technology that harnesses the power of sound and helps you achieve a certain cognitive state,” says CEO Oleg Stavitsky, one of Endel’s six co-founders. Launched in 2018, the company has since raised $22.1 million (€19.1 million) in funding, including from Amazon’s Alexa venture fund, and claims one million monthly active users. In 2023, the company struck a deal with Universal Music Group to use their technology to create new “soundscapes” using established artists’ work. endel.io

    Slay

    To understand Slay’s success, credit has to be given to Pengu, the company’s virtual pet app that has become the startup’s most popular product with more than five million users. Founded by Fabian Kamberi, Jannis Ringwald, and Stefan Quernhorst, Slay created Pengu to be part game, part social platform, where friends or couples can collaboratively raise a digital penguin. The company, which has raised $7.6 million (€6.8 million) in total, including from Accel, is currently scaling Pengu’s ability to personalize its interactions, hooking a series of LLMs to a 3D engine to create that visual experience. Pengu might respond to a child telling them they are being bullied by gifting them a drawing or sending personalized notifications to cheer them up. slay.cool

    Ovom Care

    Ovom Care is a fertility startup using data and machine learning to take the guesswork out of reproductive medicine. Since launching in 2023, co-founders Felicia von Reden, Cristina Hickman, and Lynae Brayboy have opened the company’s first fertility clinic in London—sidestepping the onerous regulatory process in Germany—and already claim to be treating hundreds of people. Alongside the physical clinic, patient app and clinic management system, Ovom also offers machine-learning algorithms that analyze patients’ blood tests, data from wearables, gamete analysis and ultrasound images to tailor the type and timing of treatment. “We’re now going into the era of precision medicine,” says CEO von Reden. “We’re tailoring [fertility] using technology”. That idea has attracted €4.8 million ($5.3 million) in seed funding led by Alpha Intelligence Capital. Within the next year, the company plans to attract medical tourists from all across Europe to its second clinic in Portugal, where treatment costs are expected to be cheaper. ovomcare.com

    Image may contain Person Teen Sitting Swing Toy Accessories Jewelry Ring Necklace Clothing Footwear and Shoe

    Felicia von Reden, founder and CEO of Ovom Care.

    PHOTOGRAPH: THOMAS MEYER

    Dryad

    When Carsten Brinkschulte’s daughter started protesting against climate change in 2018, the serial telecoms entrepreneur started to think about how he could leverage his experience for the good of the planet. The result was a startup called Dryad, launched in 2020, designed to be an early wildfire detection network. “Think of us like the Vodafone of the forest,” says Brinkschulte, one of the company’s seven co-founders. Dryad’s solar-powered mesh networks enable sensors to send alerts when they detect fire, even in remote areas where there is no signal. So far the company has sold 20,000 wildfire sensors and related hardware to 50 countries across the world, from Canada to Thailand, and to clients ranging from local governments to utility companies that want to protect their infrastructure from an inferno. Dryad has raised €22 million ($24.6 million) so far, including from German deep tech fund eCAPITAL. dryad.net

    UltiHash

    The rise of energy-hungry AI prompted the International Energy Agency to warn that the electricity consumed by data centers could double in just two years. As environmental groups discuss the risk that the technology poses to the climate, startup Ultihash has been developing a practical way to slash the data center needs of companies performing energy-intensive machine learning or training their own models. Founded in 2022, Ultihash has developed an algorithm that CEO and co-founder Tom Lüdersdorf claims can slash companies’ data storage needs by up to 60 per cent, meaning they need less data center space and reduce their carbon footprint. The company has raised $2.5 million (€2.2 million) despite still being in stealth mode. Lüdersdorf plans to launch the product later this year, after beta testing with more than 300 companies. ultihash.io

    TheBlood

    According to TheBlood’s co-founders, Isabelle Guenou and Miriam Santer, menstrual blood is an under-appreciated asset for diagnostics, containing data-rich endometrial tissue, live cells, immune cells and proteins, which are not found in ordinary blood. The pair launched the company in 2022, with the aim to use menstrual blood in an attempt to fill healthcare’s gender data gap. Since then, the firm has analyzed more than 1,000 menstrual blood samples, selling testing kits for between €35 ($39) and €120 ($133) to women who are looking for more data to inform fertility or endometriosis treatment. TheBlood also plans to license biomarker analysis or data sets to pharmaceutical companies. So far, the company has raised €1 million ($1.1million) in total, including from healthcare-focused venture firm ROX Health. theblood.io

    Qdrant

    To create generative AI, algorithms have to infer relationships between data—text, images or audio—that isn’t labeled or organized. That’s where so-called vector databases come in, helping developers extend the long-term memory of LLMs by making it easier for those models to search and analyze large amounts of data, while keeping computational costs down. Launched in 2021 by co-founders André Zayarni and Fabrizio Schmidt, Qdrant is catering to AI software developers, promising a vector search engine and database for unstructured data with an easy-to-use API. In the past three years, the company has reached 7 million downloads and 10,000 users worldwide, raising $37 million (€33.2 million) in the process including from US venture capital firm Spark Capital. qdrant.tech

    This article first appeared in the November/December 2024 edition of WIRED UK.

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    Morgan Meaker

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  • The Hottest Startups in London in 2024

    The Hottest Startups in London in 2024

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    In the “Startup-up, Scale-up” review report published last year, chancellor Rachel Reeves promised to make Britain the “high growth, start-up hub of the world”. Now, almost six months into the new government, entrepreneurs remain encouraged by the promises made in the Labour manifesto. “The ambition embodied in Great British Energy and the 2030 decarbonization targets is precisely what we need and deserve,” says Shilpika Gautam, CEO of greentech startup Opna, about Labour’s energy policies. “It’s high time the UK caught up with the policy and financing innovations in other countries, such as the Inflation Reduction Act in the US.”

    Amit Gudka, founder of Field, agrees: “We welcome Labour’s plans to double onshore wind, triple solar and quadruple offshore wind by 2030. These plans are ambitious, but not unrealistic, provided the Government continues to make clear policy decisions and create a stable policy and regulatory environment.” Other sectors, such as healthcare, share the same cautious optimism. “Labour do have a greater political mandate to genuinely reform the NHS, and Wes Streeting in particular seems pragmatic,” Meri Beckwith, co-founder of Lindus Health, says. “He’s signaled a greater willingness to work with private companies to address some of the really big challenges facing the NHS.”

    Expectations are, of course, tempered by the reality left behind by 14 years of Conservative government. For instance, in June, the UK government already had to shelve a £1.3 billion ($1.7 billion) commitment for tech and AI projects made by the previous government because no money had ever been allocated for it. “We should hope that UK industry and academia will find other avenues to mobilize the resources to build that infrastructure,” says Robin Tuluie, founder and CSEO of PhysicsX. “We don’t envy the very hard fiscal choices that the chancellor and the Labour government have to make.”

    Robin AI

    Robin AI is building an AI legal assistant that can help anyone to solve their legal problems. “I wanted to make law more accessible,” says Richard Robinson, a former corporate lawyer at Boies Schiller Flexner, and CEO of Robin AI. “We’re not here to pad out the billable hours business model of big law firms. We’re legal AI for business, not just AI for law firms.” Co-founded in 2019 by Robinson and machine learning researcher James Clough, Robin’s legal assistant is already used by hundreds of businesses like PepsiCo, PwC and Yum! Brands. Its latest product, Robin AI Reports, can, according to Robinson, analyze hundreds of legal contracts and generate single reports in minutes, allowing companies to complete legal processes that used to take weeks—for instance, M&A Due Diligence—in a matter of hours. The company has raised $26 million (£19.8 million) by Singapore-based Temasek and has recently opened an office in Singapore, adding to its offices in London and New York. robinai.com

    Gaia Family

    “I challenge you to find one fertility clinic website that doesn’t show a baby in a blue blanket front and center,” says Nader AlSalim, CEO of Gaia Family. “But how you get to that baby—and more importantly if you ever get to it— is a lot less straightforward.” AlSalim speaks from first-hand experience: his wife underwent five rounds of IVF during three years until they had a child. “There’s a lack of transparency regarding clinical outcomes and treatment prices,” he says. “People start IVF without knowing where the total bill is going to land or how far they’ll be able to go.” AlSalim launched Gaia to address those problems: the startup takes upfront payments from clients and handles all costs for up to three cycles of IVF. Clients only pay back later, in installments, if they become parents. “We apply machine learning to large public datasets to predict fertility treatment outcomes and take on the financial risk if those treatments are unsuccessful,” AlSalim says. The startup, which has raised more than $23 million (£17.5 million), is available in the UK, Spain, Greece and the US. gaiafamily.com

    Get Harley

    “I suffered from acne, seborrheic dermatitis, and eczema at various stages of my life,” says Charmaine Chow, CEO of GetHarley. “In the past, I wasted huge amounts of time, money and energy trying to figure out what works for me. I imagined a service that would enable me to meet practitioners online and would deliver the difficult-to-access, medical grade products to my door in a timely manner.” That service didn’t exist, so Chow decided to invent it. GetHarley, the online consultation and clinician matching platform she launched in 2019, currently gives more that 150,000 patients access to a network of 1,500 skincare practitioners across the UK and Ireland. “We have seen triple-digit annual growth since our launch,” she says. “We also partner with more than 500 pharma brands, which allows practitioners to be brand agnostic when they are curating personalized skincare plans.” In August 2024, the company raised $52 million (£39.6 million), led by Index Ventures. getharley.com

    Charmaine Chow, founder and CEO of GetHarley.

    PHOTOGRAPH: JACK LAWSON

    Lindus Health

    “When I was a VC investor, all the techbio companies I met shared the same frustration with clinical trials,” says Meri Beckwith, co-founder of Lindus Health. “They were late, over budget and getting exponentially more expensive. No one could really explain to me why.” Beckwith eventually realized that the culprits were the so-called contract research organizations (CRO), third-party entities that oversee and run clinical trials. “I was told that they make more money the worse the clinical trial goes,” Beckwith says. “That’s the industry’s dirty secret.” Lindus Health, founded by Beckwith and Michael Young, replaces the traditionally old-fashioned methods used by CROs with a technology platform that automates many of the phases of a clinical trial. This allows them to complete trials, on average, in half the time they usually take. “One example is real-time trial monitoring, which takes up to half of the trial’s budget,” he says. “CROs do this by physically sending someone to sites to examine paper records. Our software captures that data directly.”Lindus, which has raised $18 million (£13.7 million), has already been involved in 91 trials. lindushealth.com

    Field

    Field’s big batteries allow electricity grids to store renewable power when supply is high and release it when there’s demand. The company was founded in 2021 by former Bulb co-founder Amit Gudka. A year later, it switched on its first 20MWh battery storage site in Oldham, Greater Manchester. “That played an important part in keeping supplies steady and the lights on in the build-up to Christmas last year, when a large subsea cable transporting power between the UK and France tripped,” Gudka says. “It would have led to instability across the grid were it not for a number of batteries across the country, including ours.” The startup uses lithium-iron phosphate cells, sourced from a Chinese manufacturer, while other battery components are imported from Europe. The startup has raised £200 million ($152.4 million) from DIF Capital Partners and already has a presence in Italy, Germany and Spain. Three sites across Britain, totalling 190MWh, are currently in construction. field.energy

    Opna

    In 2017, Shilpika Gautam became the first person to stand-up paddle the entire length of the river Ganges. “On my expedition, I was introduced to renewable energy and forestry project developers who consistently shared the same challenge: they needed upfront financing to get started,” Gautam says. In 2022, she launched Opna, a platform that allows corporations that want to find, fund and monitor carbon removal projects. “Our mission is to unlock capital for high-quality climate projects that address climate change with speed, scale, and equity,” she says. So far, it has worked with more than 45 projects, in sectors such as agroforestry, blue carbon, biochar and direct air capture, generating more than $340 million (£401 million) in carbon credits. “We verify the integrity of information provided by suppliers and review all the risks associated with a project,” she says. “Our standardized diligence, contracting, and portfolio management tools can save buyers hundreds of thousands of dollars in costs, shrink deal timelines, and de-risk net-zero journeys by actively managing carbon removal portfolios for several years.” Opna has raised a seed round of $6.5 million (£7.6 million) led by Atomico. opna.earth

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    Shilpika Gautam, CEO and founder of climate fintech, Opna.

    PHOTOGRAPH: THOMAS MEYER

    Sylvera

    Sylvera verifies and rates the performance of carbon offsetting projects, helping corporate buyers make more informed decisions when purchasing carbon credits. The platform uses machine learning algorithms to assess factors such as the project’s carbon impact and accuracy of reporting based on a range of datasets from satellite data to LIDAR (light detection and ranging) scans. “We’re obsessed with getting project ratings right,” Allister Furey, CEO of Sylvera, says. “We spend up to 120 hours putting together every project rating and analysis, which includes rounds of testing to ensure we’ve come to the correct conclusion.” In May, it launched the Sylvera Catalog, which gives investors access to an overview of nearly 20,000 projects, from biochar to landfill methane. In July 2023, the company raised $57 million (£43.4 million) in series B funding led by Balderton Capital, taking its total external investment to $96 million (£73 million) since being founded in 2020 by Furey and Sam Gill. sylvera.com

    PhysicsX

    PhysicsX uses machine learning to run simulations for engineers in industries such as aerospace, automotive, energy and semiconductors. “AI-driven physics and chemistry simulation will fundamentally transform complex engineering and manufacturing,” says Robin Tuluie, CSEO of PhysicsX. “Our technology replaces standard simulation models with Large Physics Models. These models are as accurate as numerical simulation, but execute in a second or less. We’re talking about speeding up physics simulation by 104-105 times.” Although they can’t disclose names, Tuluie says clients already include a top Formula One team and major automotive and renewables companies. Founded by Tuluie, an astrophysicist and former chief scientist at Mercedes F1 team, and Jacomo Corbo, co-founder of data agency QuantumBlack, the startup has raised $32 million (£24.3 million) in funding led by General Catalyst. physicsx.ai

    Newcleo

    Nuclear technology startup Newcleo is developing a mini nuclear power plant which uses nuclear waste as fuel. Founded in 2021 by physicist Stefano Buono, the startup has already raised more than €400 million (£338.8 million) and employs more than 750 people located in fifteen offices across the UK, France, Switzerland and Italy. In 2024, NewCleo dropped plans to build a power plant in Cumbria, opting instead to invest £4 billion (€4.7 billion) in the south of France following personal lobbying from French President Emmanuel Macron. A demonstration model is currently being built in Italy and the first 30 MW prototypes are planned for 2030. newcleo.com

    Volt

    Volt is an open payments platform that enables merchants to receive direct payments in real-time. “I saw an industry that was ripe for disruption, based on technologies imagined and implemented in the 50s,” Tom Greenwood, CEO of Volt, says. “I could see that there was a new generation of payment infrastructure coming that was real-time.” Founded by Greenwood, Steffen Vollert and Jordan Lawrence, Volt is live today across 31 countries, including Europe, the UK, Brazil and Australia. In June last year, they raised a $60 million (£45.7 million) Series B led by IVP. Clients include FarFetch, Robinhood, Next, KLM, Air France and Xe.com. volt.io

    This article first appeared in the November/December 2024 edition of WIRED UK.

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    João Medeiros

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