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Tag: Epidiolex

  • US Medicare Potentially Adding Coverage For CBD

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    Discover what US Medicare potentially adding coverage for CBD means for pain relief, wellness, costs, and patient care access.

    In good news, US Medicare potentially adding coverage for CBD.  The federal agency  is quietly moving toward a potential shift which could make cannabidiol (CBD) — the non-intoxicating compound extracted from hemp — more accessible to older Americans. Recent regulatory proposals and reporting indicate the Centers for Medicare & Medicaid Services (CMS) is considering ways for some Medicare programs, particularly Medicare Advantage, to reimburse certain hemp-derived products who meet federal and state rules. If finalized, the change would be a major step for seniors who already show high interest in CBD as an alternative for pain, sleep and anxiety.

    RELATED: Can Microdosing Marijuana Help You

    CBD’s popularity has exploded in the past decade. Shelves in pharmacies and grocery stores are stocked with tinctures, capsules, creams and gummies marketed to relieve everything from chronic pain to insomnia. Advocates argue broader coverage would lower out-of-pocket costs for seniors and integrate CBD into managed care pathways; critics caution federal law and uneven evidence mean wide insurance coverage would be premature. Reporting on this evolving policy debate shows regulators are trying to thread the needle — permitting coverage for a limited set of compliant hemp products while avoiding conflict with federal drug law.

    Photo by Olena Ruban/Getty Images

    What does the medical evidence say? The clearest, FDA-backed use of CBD today is for rare seizure disorders: Epidiolex, a prescription CBD product, is approved to treat Lennox-Gastaut syndrome, Dravet syndrome and seizures associated with tuberous sclerosis complex. Outside those indications, research is promising but mixed. Systematic reviews and clinical summaries indicate cannabinoids can help with chemotherapy-related nausea, some chronic pain syndromes and spasticity from multiple sclerosis, while CBD specifically has shown benefit as an adjunct for certain refractory epilepsies. However, many other claims — for anxiety, arthritis pain, sleep, and neurodegenerative disease — rely on smaller studies, observational data or preclinical work and need larger randomized trials.

    Medical authorities urge cautious optimism. The National Institutes of Health / NLM clinical reviews and summaries map the most robust evidence (epilepsy) and identify risks such as liver enzyme elevations and drug interactions require monitoring. The Mayo Clinic likewise notes while CBD is under investigation for many conditions, most over-the-counter CBD products lack FDA approval and strong evidence, and only one prescription CBD product is currently FDA-approved. Those organizations remain important resources for clinicians and patients weighing potential benefits and harms.

    RELATED: What About A Cannabis Cocktail/ Holiday Party

    What would Medicare coverage mean in practice? If CMS finalizes a rule allowing certain hemp-derived CBD products into benefits, coverage would likely be narrow: prescription formulations with proven indications or tightly specified, compliant hemp products produced under strict quality standards. Policymakers must address product quality, labeling, dosing, and safety surveillance before broad reimbursement. Until then, seniors interested in CBD should consult their clinicians about potential benefits, interactions with other medications, and whether an FDA-approved prescription product is appropriate.

    As regulators consider coverage, the debate will hinge on two forces: growing consumer demand from older Americans and the medical community’s call for better evidence and safeguards. The coming months could bring concrete policy steps from CMS; for now the conversation spotlights a larger question — how to responsibly integrate a widely used but unevenly regulated product into mainstream healthcare.

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    Amy Hansen

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  • CBD Leads to Nonseizure Improvements, AbbVie Launches 24-Hour Levodopa Infusion in EU, CNM-Au8 Improves Visual Function and Cognition – Medical Marijuana Program Connection

    CBD Leads to Nonseizure Improvements, AbbVie Launches 24-Hour Levodopa Infusion in EU, CNM-Au8 Improves Visual Function and Cognition – Medical Marijuana Program Connection

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    WATCH TIME: 4 minutes

    Welcome to this special edition of Neurology News Network. I’m Marco Meglio.

    In a survey study of patients with either Lennox-Gastaut syndrome or Dravet syndrome, findings showed that treatment with add-on cannabidiol (CBD; Epidiolex) led to improvements in nonseizure outcomes, regardless of reduction in seizure frequency. Despite the limitations associated with a retrospective survey-based study design, investigators concluded that further evaluation of CBD on nonseizure outcomes in these patient populations is warranted. On nonseizure domains of alertness, cognition, and executive function, 85% of respondents reported improvements in at least 1 survey question. This continued across several other nonseizure-related domains of emotional functioning (82%), language and communication (79% in nonverbal patients and 74% in verbal), and activities of daily living (51%).

    More than a year after it received approval by the European Commission, AbbVie has announced the European market launch of foslevodopa/foscarbidopa (Produodopa), the first and only 24-hour infusion of levodopa-based therapy for patients with advanced Parkinson disease (PD). Prior to the launch, the therapy had received authorization through the Decentralized Procedure in the third quarter of 2022, followed by a CE mark in November of 2023. Also referred to as ABBV-951, this formulation of levodopa and carbidopa prodrugs are delivered as a 24-h/day continuous subcutaneous infusion (CSCI) via…

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    MMP News Author

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  • Do CBD Gummies Actually Work

    Do CBD Gummies Actually Work

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    CBD has been touted as a gentle health aide a way to reduce stress, a way to sleep better and way to relax.  Found everywhere from Amazon to Walmart, you can pick it up – especially when you feel the need for help. But do CBD gummies actually work?

    CBD comes from cannabidiol, one of the two best-known active compounds derived from the marijuana plant. The other is tetrahydrocannabinol, or THC, which is the substance that that produces the “high” from marijuana. It can also be derived from hemp.

    CBD does not get you high, but it can your consciousness. You may feel mellow, experience less pain, and be more comfortable. Some CBD products do contain small amounts of THC.

    RELATED: Are CBD Drinks Legal?

    Epidiolex is the only FDA-approved prescription CBD medicine, which among many things, means that it has a safety and efficacy profile that has been thoroughly evaluated in clinical trials. The rest of the CBD industry is going through growing pains  there’s a mess going on with plenty of important guidelines, like dosage, purity and strength of the product. One of the many problems this disarray causes is the variability among CBD products. While some might provide noticeable effects, others might not even contain enough CBD to register in your system.

    Photo by Pharma Hemp Complex via Unsplash

     

    Yes, there is evidence CBD works for some conditions, but certainly not all the conditions it is being promoted for these days. According to different CBD gummy manufacturers, these products can provide relief for a wide range of ailments, including pain, anxiety, inflammation, insomnia and even depression. These statements have no scientific accuracy, however, since few tests have been conducted have been limited to CBD oil.

    Anecdotally, plenty of people believe in the effect of CBD gummies, although the dosage still causes some issues. While some claim to feel positive effects after consuming two gummies, others might have to up the dosage until they feel something. With all the hype surrounding CBD gummies, this “something” might also be imagined; a placebo effect could be at work making you feel like you should be experiencing some sort of sensation because you just ingested cannabis.

    RELATED: These Are The 4 Biggest Problems With CBD Products

    Although few scientific tests have been conducted, CBD oil has been associated with plenty of positive side effects, and all of these gummies, if purchased correctly, contain a good amount of oil. You can also expect some clarity in the near future, since the industry is growing and learning the nuance exists between the different cannabis products and plants.

    As usual, if you’re interested in trying out a new cannabis product, go slow. Purchase a bottle of reviewed CBD gummies and start off with a slow dose, checking in with your body for any changes and/or improvements. The worst thing which could happen is you ingest a ton of sugar and start to feel a little drowsy.

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    Maria Loreto

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