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Tag: Disease outbreaks

  • Eye drops linked to US drug-resistant bacteria outbreak

    Eye drops linked to US drug-resistant bacteria outbreak

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    NEW YORK — U.S. health officials are advising people to stop using over-the-counter eye drops that have been linked to an outbreak of drug-resistant infections.

    The Centers for Disease Control and Prevention on Wednesday night sent a health alert to physicians, saying the outbreak includes at least 55 people in 12 states. One died.

    Disease investigators have linked the infections, including some found in blood, urine and lungs, to EzriCare Artificial Tears. Many of the patients said they had used the product, which is a lubricant used to treat irritation and dryness.

    The infections were all caused by a bacteria called Pseudomonas aeruginosa. Investigators detected that kind of bacteria in open EzriCare bottles, but further testing was underway to see if the strains matched.

    EzriCare said it is not aware of any evidence definitively linking the outbreak to the product, but that it has stopped distributing the eye drops. It also has a notice on its website urging consumers to stop using the drops.

    “To the greatest extent possible, we have been contacting customers to advise them against continued use of the product. We also immediately reached out to both CDC and FDA and indicated our willingness to cooperate with any requests they may have of us,” the company said.

    Two weeks ago, the CDC warned medical professional societies about the possible connection between the drops and the infections. The Wednesday alert was a broader, more public warning.

    Infections were diagnosed in patients in California, Colorado, Connecticut, Florida, New Jersey, New Mexico, New York, Nevada, Texas, Utah, Washington and Wisconsin. One patient — in Washington — died with a blood infection. At least three others suffered permanent vision loss. They were in California and New Jersey.

    The outbreak is considered particularly worrisome because the bacteria driving it are resistant to standard antibiotics.

    Investigators found the bacteria were not susceptible to any antibiotics routinely tested at public health laboratories. However, a newer antibiotic named cefiderocol did seem to work.

    How could eye drops cause infections in the blood or lungs? The eye connects to the nasal cavity through the tear ducts. Bacteria can move from the nasal cavity into the lungs. Also, bacteria in these parts of the body can seed infections at other sites such as in the blood or wounds, CDC officials said.

    The product is manufactured in India by Global Pharma Healthcare Pvt Ltd., EzriCare said.

    ___

    The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.

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  • The end of the Covid health emergency won’t slow FDA clearance of shots and treatments

    The end of the Covid health emergency won’t slow FDA clearance of shots and treatments

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    Vials and a medical syringe seen displayed in front of the Food and Drug Administration (FDA) of the United States logo. FDA finds the COVID-19 vaccine.

    Pavlo Gonchar | LightRocket | Getty Images

    The Food and Drug Administration on Tuesday said its emergency authorizations of Covid vaccines, tests and treatments will not be impacted by the end of the public health emergency this spring.

    President Joe Biden is planning to terminate in May the public health and national emergencies declared in response to the Covid pandemic three years ago, the White House said Monday. The public health emergency gave U.S. health regulators expanded powers to respond faster to the pandemic.

    The FDA’s emergency powers, however, aren’t directly tied to public health declaration, according to the agency.

    Former Health Secretary Alex Azar made separate determinations in February and March of 2020 under the Food, Drug and Cosmetics Act that the circumstances of the pandemic justified the authorization of vaccines, treatments and tests for emergency use.

    The FDA used its emergency powers to authorize the Pfizer, Moderna, Johnson & Johnson and Novavax vaccines. The agency also authorized the oral antivirals Paxlovid and molnupiravir, several antibody treatments as well as numerous tests and other medical devices on an emergency basis.

    “Existing emergency use authorizations (EUAs) for products will remain in effect and the agency may continue to issue new EUAs going forward when criteria for issuance are met,” The FDA wrote in post on Twitter Monday.

    Emergency authorizations allow the FDA to roll out medical products before they receive the agency’s full approval. This allows the agency to respond more swiftly to public health crises.

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  • CDC urges people with weak immune systems to take extra precautions after Covid subvariants knock out Evusheld

    CDC urges people with weak immune systems to take extra precautions after Covid subvariants knock out Evusheld

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    The Centers for Disease Control and Prevention on Friday urged people with weak immune systems to take extra precautions to avoid Covid after the dominant omicron subvariants knocked out a key antibody treatment.

    These precautions include wearing a high quality mask and social distancing when it’s not possible to avoid crowded indoor spaces, according to the CDC.

    The guidance comes after the Food and Drug Administration on Thursday pulled its authorization of Evusheld, a combination antibody injection that people with weak immune systems took as an additional layer of protection to prevent Covid infection.

    The FDA pulled Evusheld because it is not effective against 95% of the omicron subvariants circulating in the U.S. This includes the XBB subvariants which are now causing 64% of new cases, as well as the BQ family that is responsible for 31% of reported infections.

    Although most Americans have largely returned to normal life as the Covid pandemic has ebbed, people with weak immune systems remain at higher risk of severe disease because they do not mount as strong of an immune response to the vaccines.

    Still, it is important for people with weak immune systems to stay up to date on their Covid vaccines by receiving the omicron booster because the shots can slash the risk of severe disease, according to the CDC.

    If you have a weak immune system and develop Covid symptoms, you should get tested as soon as possible and receive treatment with an antiviral within five to seven days, according to CDC.

    Available antivirals include Paxlovid, remdesivir or molnupiravir, but patients should talk to their doctor to find out which treatment is best. Some people cannot take Paxlovid due to how it interacts with other drugs they are taking.

    People with weak immune systems include cancer patients who are on chemotherapy, organ transplant patients who are taking medication for their transplant, people with advanced HIV infection, and those born with immune deficiencies.

    Some 7 million adults in the U.S. have a condition, like cancer, that compromises their immune system, according to the CDC.

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  • CDC says it’s ‘very unlikely’ Pfizer booster carries stroke risk for seniors after launching review

    CDC says it’s ‘very unlikely’ Pfizer booster carries stroke risk for seniors after launching review

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    The Centers for Disease Control and Prevention on Friday said it is “very unlikely” the Pfizer omicron booster carries a risk of stroke for seniors after it launched an investigation into a preliminary safety concern detected by one of its monitoring systems.

    The CDC, in a statement posted to its website Friday, said a surveillance system called the Vaccine Safety Datalink detected a possible risk for stroke in people ages 65 and older who received the Pfizer booster shot targeting the omicron Covid variant. A CDC spokesperson said this issue was first detected in late November.

    By mid-December, the CDC concluded the concern was persisting and launched an investigation into whether seniors are more likely to have a stroke in the first 21 days after receiving the Pfizer booster, the spokesperson said. A similar preliminary signal was not detected for Moderna’s booster.

    The VSD monitoring system found that 130 people ages 65 and older had a stroke within 21 days of receiving the Pfizer omicron booster among about 550,000 seniors who received the shot, the CDC spokesperson said. No deaths have been reported. The Washington Post earlier reported the news.

    No other surveillance system has detected a similar safety concern for the Pfizer booster so far, according to the CDC. Investigators have not found an increased risk of stroke following the Pfizer booster after reviewing data from the Center for Medicare and Medicaid Services, the Department of Veterans Affairs, the Vaccine Adverse Reporting System and Pfizer’s global safety database.

    “Although the totality of the data currently suggests that it is very unlikely that the signal in VSD represents a true clinical risk, we believe it is important to share this information with the public, as we have in the past, when one of our safety monitoring systems detects a signal,” the CDC said in the post on its website.

    The monitoring systems often detect safety signals that are due to factors other than the vaccine, according to the CDC’s Friday statement. The agency spokesperson said investigators hope to have a clearer picture and more data in the coming weeks.

    The investigation will be discussed at an upcoming meeting of the Food and Drug Administration’s panel of independent vaccine experts on Jan. 26.

    In a statement Friday, Pfizer said there is no evidence to conclude that ischemic stroke is associated with company’s Covid vaccine. Neither Pfizer and its German partner BioNTech, nor the CDC or the FDA, have observed such an association in numerous other monitoring systems in the U.S. and globally, company spokesperson Kit Longley said.

    “Compared to published incidence rates of ischemic stroke in this older population, the companies to date have observed a lower number of reported ischemic strokes following the vaccination with the omicron BA.4/BA.5-adapted bivalent vaccine,” Longley said.

    The CDC has not changed its recommendation for the Pfizer omicron shot. Everyone ages 5 and older is eligible for the booster after completing their primary vaccine series. The youngest kids ages 6 months through 4 years old receive the omicron shot as the third dose of their primary series.

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  • Today in History: December 31, Clemente dies on aid flight

    Today in History: December 31, Clemente dies on aid flight

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    Today in History

    Today is Saturday, Dec. 31, the 365th and final day of 2022.

    Today’s Highlight in History:

    On Dec. 31, 2019, the health commission in the central Chinese city of Wuhan announced that experts were investigating an outbreak of respiratory illness and that most of the victims had visited a seafood market in the city; the statement said 27 people had become ill with a strain of viral pneumonia and that seven were in serious condition.

    On this date:

    In 1879, Thomas Edison first publicly demonstrated his electric incandescent light by illuminating some 40 bulbs at his laboratory in Menlo Park, New Jersey.

    In 1904, New York’s Times Square saw its first New Year’s Eve celebration, with an estimated 200,000 people in attendance.

    In 1951, the Marshall Plan expired after distributing more than $12 billion in foreign aid.

    In 1972, Major League baseball player Roberto Clemente, 38, was killed when a plane he chartered and was traveling on to bring relief supplies to earthquake-devastated Nicaragua crashed shortly after takeoff from Puerto Rico.

    In 1974, private U.S. citizens were allowed to buy and own gold for the first time in more than 40 years.

    In 1978, Taiwanese diplomats struck their colors for the final time from the embassy flagpole in Washington, D.C., marking the end of diplomatic relations with the United States.

    In 1985, singer Rick Nelson, 45, and six other people were killed when fire broke out aboard a DC-3 that was taking the group to a New Year’s Eve performance in Dallas.

    In 1986, nearly 100 people were killed when fire broke out in the Dupont Plaza Hotel in San Juan, Puerto Rico. (Three hotel workers later pleaded guilty in connection with the blaze.)

    In 1987, Robert Mugabe (moo-GAH’-bay) was sworn in as Zimbabwe’s first executive president.

    In 1995, the syndicated comic strip “Calvin and Hobbes,” created by Bill Watterson, came to an end after a 10-year run.

    In 1999, Russian President Boris Yeltsin announced his resignation (he was succeeded by Vladimir Putin).

    In 2020, authorities arrested a suburban Milwaukee pharmacist suspected of deliberately ruining hundreds of doses of coronavirus vaccine by removing them from refrigeration. (Steven Brandenburg, an admitted conspiracy theorist who believed vaccines were the product of the devil, would be sentenced to three years in prison.) Britain completed its economic break from the European Union.

    Ten years ago: Racing the clock, the White House reached a New Year’s Eve accord with Senate Republicans to block across-the-board tax increases and spending cuts in government programs due to take effect at midnight. Private recreational marijuana clubs opened in Colorado, less than a month after Gov. John Hickenlooper signed into law a constitutional amendment allowing recreational pot use.

    Five years ago: New Yorkers endured the second-coldest New Year’s Eve celebration on record; the temperature in the city was 10 degrees Fahrenheit as a glittering crystal ball dropped with a burst of confetti and dazzling fireworks in Times Square. Bitterly cold temperatures spread across the Deep South; the dangerous temperatures would grip wide areas of the U.S. from Texas to New England for days. The Cleveland Browns joined the 2008 Detroit Lions as the only teams in NFL history to go 0-and-16, losing to the Pittsburgh Steelers 28-24.

    One year ago: Betty White, a television mainstay for more than 60 years who brought a combination of sweetness and edginess to shows including “The Mary Tyler Moore Show” and “The Golden Girls,” died less than three weeks before she would have turned 100. Flight cancellations surged again on the last day of 2021, with airlines blaming it on crew shortages related to the spike in COVID-19 infections. A crowd that was limited to about 15,000 because of the coronavirus pandemic cheered the annual New Year’s Eve ball drop in New York City’s Times Square. Although stocks slipped on the last day of the year, they still ended 2021 with some big gains; the S&P 500 was up 26.9% for the year.

    Today’s Birthdays: TV producer George Schlatter is 93. Actor Sir Anthony Hopkins is 85. Actor Sarah Miles is 81. Actor Barbara Carrera is 81. Rock musician Andy Summers is 80. Actor Sir Ben Kingsley is 79. Producer-director Taylor Hackford is 78. Fashion designer Diane von Furstenberg is 76. Actor Tim Matheson is 75. Pop singer Burton Cummings is 75. Actor Joe Dallesandro is 74. Rock musician Tom Hamilton (Aerosmith) is 71. Actor James Remar is 69. Actor Bebe Neuwirth is 64. Actor Val Kilmer is 63. Singer Paul Westerberg is 63. Actor Don Diamont is 60. Rock musician Ric Ivanisevich (Oleander) is 60. Rock musician Scott Ian (Anthrax) is 59. Actor Gong Li is 57. Author Nicholas Sparks is 57. Actor Lance Reddick is 53. Pop singer Joe McIntyre is 50. Rock musician Mikko Siren (Apocalyptica) is 47. Donald Trump Jr. is 45. Rapper PSY (Park Jae-sang) is 45. Rock musician Bob Bryar is 43. Rock musician Jason Sechrist (Portugal. The Man) is 43. Actor Ricky Whittle is 43. Republican Sen. Josh Hawley of Missouri is 43. Actor/singer Erich Bergen is 37. DJ/vocalist Drew Taggart (The Chainsmokers) is 33. U.S. Olympic beach volleyball gold medalist Alix Klineman is 33. U.S. Olympic gold medal gymnast Gabby Douglas is 27.

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  • Highly immune evasive omicron XBB.1.5 variant is quickly becoming dominant in U.S. as it doubles weekly

    Highly immune evasive omicron XBB.1.5 variant is quickly becoming dominant in U.S. as it doubles weekly

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    Gilnature | Istock | Getty Images

    The Covid Omicron XBB.1.5 variant is rapidly becoming dominant in the U.S. because it is highly immune evasive and appears more effective at binding to cells than related subvariants, scientists say.

    XBB.1.5 now represents about 41% of new cases nationwide in the U.S., nearly doubling in prevalence over the past week, according to the data published Friday by the Centers for Disease Control and Prevention. The subvariant more than doubled as a share of cases every week through Dec. 24. In the past week, it nearly doubled from 21.7% prevalence.

    Scientists and public health officials have been closely monitoring the XBB subvariant family for months because the strains have many mutations that could render the Covid-19 vaccines, including the omicron boosters, less effective and cause even more breakthrough infections.

    XBB was first identified in India in August. It quickly become dominant there, as well as in Singapore. It has since evolved into a family of subvariants including XBB.1 and XBB.1.5.

    Andrew Pekosz, a virologist at Johns Hopkins University, said XBB.1.5 is different from its family members because it has an additional mutation that makes it bind to cells better.

    “The virus needs needs to bind tightly to cells to be more efficient at getting in and that could help the virus be a little bit more efficient at infecting people,” Pekosz said.

    Yunlong Richard Cao, a scientist and assistant professor at Peking University, published data on Twitter Tuesday that indicated XBB.1.5 not only evades protective antibodies as effectively as the XBB.1 variant, which was highly immune evasive, but also is better at binding to cells through a key receptor.

    Scientists at Columbia University, in a study published earlier this month in the journal Cell, warned that the rise of subvariants such as XBB could “further compromise the efficacy of current COVID-19 vaccines and result in a surge of breakthrough infections as well as re-infections.”

    The XBB subvariants are also resistant to Evusheld, an antibody cocktail that many people with weak immune systems rely on for protection against Covid infection because they don’t mount a strong response to the vaccines.

    The scientists described the resistance of the XBB subvariants to antibodies from vaccination and infection as “alarming.” The XBB subvariants were even more effective at dodging protection from the omicron boosters than the BQ subvariants, which are also highly immune evasive, the scientists found.

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    Dr. David Ho, an author on the Columbia study, agreed with the other scientists that XBB.1.5 probably has a growth advantage because it binds better to cells than its XBB relatives. Ho also said XBB.1.5 is about as immune evasive as XBB and XBB.1, which were two of the subvariants most resistant to protective antibodies from infection and vaccination so far.

    Dr. Anthony Fauci, who is leaving his role as White House chief medical advisor, has previously said that the XBB subvariants reduce the protection the boosters provide against infection “multifold.”

    “You could expect some protection, but not the optimal protection,” Fauci told reporters during a White House briefing in November.

    Fauci said he was encouraged by the case of Singapore, which had a major surge of infections from XBB but did not see hospitalizations rise at the the same rate. Pekosz said XBB.1.5, in combination with holiday travel, could cause cases to rise in the U.S. But he said the boosters appear to preventing severe disease.

    “It does look like the vaccine, the bivalent booster is providing continued protection against hospitalization with these variants,” Pekosz said. “It really emphasizes the need to get a booster particularly into vulnerable populations to provide continued protection from severe disease with these new variants.”

    Health officials in the U.S. have repeatedly called on the elderly in particular to make sure they are up to date on their vaccines and get treated with the antiviral Paxlovid if they have a breakthrough infection.

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  • More European nations tighten COVID rules for China flights

    More European nations tighten COVID rules for China flights

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    PARIS — France, Spain and England will implement tougher COVID-19 measures for passengers arriving from China, authorities said Friday.

    France’s government is requiring negative tests, and is urging French citizens to avoid nonessential travel to China. France is also reintroducing mask requirements on flights from China to France.

    French health authorities will carry out random PCR tests at airports on passengers arriving from China to identify potential new coronavirus variants. The new rules take effect on Sunday, but officials said it would be a few days before they are fully in place.

    The U.K. government announced that anyone traveling to England on direct flights from China would be required to take a pre-departure test from Jan. 5.

    Health Secretary Steve Barclay said that the U.K. was taking a “balanced and precautionary approach.” He described the measures as “temporary” while officials assess COVID-19 statistics.

    France and Spain said they would continue to push for a Europe-wide policy.

    France’s hospitals have struggled in recent weeks with a large number of patients because of three concurrent outbreaks: the seasonal flu, a wave of bronchitis cases and COVID-19.

    Earlier, Spain’s government said it would require all air passengers coming from China to have negative tests or proof of vaccination.

    Health Minister Carolina Darías told reporters that Spain would be pushing for similar measures at a European level following the surge in cases in China. She said coronavirus health controls would be stepped up at Spanish airports.

    Darías didn’t specify when the new requirement would take effect.

    Spain made the announcement after Italy said it would require coronavirus tests for airline passengers from China. Health officials from the 27-member European Union on Thursday promised to continue talks on seeking a common approach but held back from imposing restrictions.

    “There exists a shared concern internationally and nationally over the evolution of cases in China and the difficulty to make a correct evaluation of the COVID-19 situation given the scant information that we have available,” Darías said.

    Darías noted that China would be lifting travel restrictions from Jan. 8 and there was likely to be a major increase in people traveling abroad. She said the chief concern was the possible emergence of new coronavirus variants and it was important to act fast.

    The United States announced new COVID-19 testing requirements Wednesday for travelers from China, joining some Asian nations that had imposed restrictions. Japan on Friday started requiring tests for passengers arriving from China.

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  • U.S. records 100 million Covid cases, but more than 200 million Americans have probably had it

    U.S. records 100 million Covid cases, but more than 200 million Americans have probably had it

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    The U.S. recorded more than 100 million formally diagnosed and reported Covid-19 cases this week, but the number of Americans who’ve actually had the virus since the beginning of the pandemic is probably more than twice as high.

    Covid-19 has easily infected more than 200 million in the U.S. alone since the beginning of the pandemic — some people more than once. The virus continues to evolve into more transmissible variants that dodge immunity from vaccination and prior infection, making transmission incredibly difficult to control as we go into the fourth year of the pandemic.

    The U.S. officially recorded more than 100 million cases as of Tuesday, just under one third of the total population, according to data from the Centers for Disease Control and Prevention. The data isn’t perfect and likely a huge undercount of the actual number of infections, scientists say. While it counts people who’ve tested positive more than once or caught Covid multiple times, it doesn’t capture the number of Covid patients who were asymptomatic and never test or tested at home and didn’t report it.

    Dr. Tom Frieden, former CDC director under the Obama administration, estimates that the reported data reflects less than half of the actual total.

    “There are have been at least 200 million infections in the U.S., so this is a small portion of them,” Frieden said. “The question really is will we be better prepared for Covid and other health threats going forward, and the jury is very much still out on that,” he said.

    The CDC estimated last spring that nearly 187 million people in the U.S. had caught Covid at least once through February 2022, more than double the number of officially reported cases at the time. The estimate was based on a survey of commercial lab data that found about 58% of Americans had antibodies as a result of a Covid infection. The survey did not account for re-infections or antibodies from vaccination.

    The CDC has subsequently recorded more than 21 million confirmed cases from March through Dec. 21 of this year, although this is an underestimate because people who use rapid tests at home are not picked up in the data.

    The more than 21 million additional confirmed cases on top of the CDC’s February estimate of about 187 million total infections gives a low-end estimate of more than 208 million infections since the pandemic began.

    “It’s really hard to stop this virus, and that’s one of the reasons why we’ve shifted the focus to hospitalizations and deaths and not just counting cases,” said Jennifer Nuzzo, an epidemiologist and director of the Pandemic Center at Brown University School of Public Health.

    The U.S. has made significant progress since the darkest days of the pandemic. Deaths have dropped about 90% from the pandemic peak in January 2021 when more than 3,000 people were succumbing to the virus daily before widespread vaccination. Daily hospital admissions are down 77% from a peak of more than 21,000 in January 2022 during the massive omicron surge.

    Despite this progress, deaths and hospitalizations remain stubbornly high given the widespread availability vaccines and treatments. About 400 people are still dying a day from the virus and about 5,000 are admitted to the hospital daily. The virus is still circulating at what would have been considered a high level earlier in the pandemic, with nearly 70,000 confirmed cases reported a day on average, a significant undercount due to testing at home.

    More than a million people have died in the U.S. from Covid since the pandemic began, more than any another country in the world.

    “I think people have gotten hardened to it,” Frieden said of Covid’s toll. “Covid is a new bad thing in our environment, and it’s likely to be here for the long term. We don’t know how this will evolve, whether it will get less virulent, more virulent — have years that get better and worse.”

    White House chief medical advisor Dr. Anthony Fauci, who is stepping down this month, has said the U.S. can consider the pandemic over when Covid hospitalizations and deaths decline to a level similar to the burden from the flu.

    For the first, the two viruses are circulating simultaneously at high levels. From October through the first week of December, flu killed 12,000 people while Covid took more than 27,000 lives during that period.

    “We’re still in the middle of this — it is not over,” Fauci told the radio show “Conversations on Health Care” in November. “Four hundred deaths per day is not an acceptable level. We want to get it much lower than that.”

    Frieden said 95% of people who are dying from Covid aren’t up to date on their shots and 75% of people who would benefit from the antiviral Paxlovid are not receiving it.

    “We should celebrate these great tools we have, but we’re not doing a good job of getting getting them into people and that would not just save lives, but reduce the disruption from from Covid,” he said.

    Dr. Ashish Jha, the White House Covid taskforce coordinator, has said people who are up to date on their vaccines and get treated when they have a breakthrough infection face almost no risk of dying from Covid at this point in the pandemic. Jha has called on the older Americans in particular, who are more vulnerable to severe illness, to get boosted so they have more protection during the holidays.

    “There are still too many older Americans who have not gotten their immunity updated who have not gotten themselves protected,” Jha told reporters at the White House last week.

    Michael Osterholm, a leading epidemiologist, said new Covid variants will pose the biggest threat to progress the U.S. has made in 2023.

    China has eased its stringent zero Covid policy, which sought to crush outbreaks of the virus, in response to widespread social unrest during the fall. Infections are now soaring in the country, raising concern that Covid now has even more space to mutate.

    The virus has continued to mutate into ever more transmissible versions of omicron over the past year, at the same time that immunity from vaccination or prior infection has waned off.

    “We want to believe that after three years of activity, all the immunity that we should have acquired through either vaccination or previous infection should protect us,” said Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota. “But with waning immunity and the variants — we can’t say that.”

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  • China to scrap COVID-19 quarantine for incoming passengers

    China to scrap COVID-19 quarantine for incoming passengers

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    BEIJING — China will drop a COVID-19 quarantine requirement for passengers arriving from abroad starting Jan. 8, the National Health Commission announced Monday in the latest easing of the country’s once-strict virus-control measures.

    Currently, arriving passengers must quarantine for five days at a hotel, followed by three days at home. That is down from as much as three weeks in the past.

    The scrapping of the quarantine requirement is a major step toward fully reopening travel with the rest of the world, which the government severely curtailed in a bid to keep the virus out.

    The restrictions have prevented most Chinese from traveling abroad, limited face-to-face diplomatic exchanges and sharply reduced the number of foreigners in China for work and study.

    China’s health commission said that steps would be taken to make it easier for some foreigners to enter the country, though it didn’t include tourists. It did indicate that Chinese would be gradually allowed to travel abroad for tourism again, an important source of revenue for hotels and related businesses in many countries.

    People coming to China will still need a negative virus test 48 hours before departure and passengers will be required to wear protective masks on board, an online post from the health commission said.

    China abruptly dropped many of its pandemic restrictions earlier this month, sparking widespread outbreaks that have swamped hospital emergency rooms and funeral homes.

    The move followed rare public protests against the restrictions, which have slowed the economy, putting people out of work and driving restaurants and shops out of business.

    For more than 2 ½ years, Chinese authorities enforced a strict zero-COVID approach that became a signature policy of leader Xi Jinping.

    The arrival of the fast-spreading omicron variant in late 2021 made the strategy increasingly untenable, requiring ever-wider lockdowns that stymied growth and disrupted lives.

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  • China announces rollback of strict anti-COVID-19 measures

    China announces rollback of strict anti-COVID-19 measures

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    BEIJING — In a sharp reversal, China has announced a series of measures rolling back some of its most draconian anti-COVID-19 restrictions, including limiting harsh lockdowns and ordering schools without known infections to resume regular classes.

    The National Health Commission in a 10-point announcement on Wednesday stipulated that COVID-19 tests and a clean bill of health displayed on a smartphone app would no longer be required, apart from vulnerable areas such as nurseries, elderly care facilities and schools. It also limited the scale of lockdown to individual apartment floors and buildings, rather than entire districts and neighborhoods.

    People who test positive for the virus will be able to isolate at home rather than in overcrowded and unsanitary field hospitals, and schools where there have been no outbreaks must return to in-class teaching.

    The announcement follows recent street protests in several cities over the strict “zero-COVID” policy now entering its fourth year, which has been blamed for upending ordinary life, travel and employment while dealing a harsh blow to the national economy.

    China has sought to maintain the hardline policy while keeping the world’s second-largest economy humming, but public frustration with the restrictions appears to have finally swayed the opinion of officials who had championed “zero-COVID” as superior to the approach of foreign nations that have opened up in hopes of learning to live with the virus.

    “Relevant departments in all localities must further improve their political positions … and resolutely correct the ‘one size fits all’ simplified approach,” the commission said in its statement posted on its website.

    Officials, often those at the local level under intense pressure to prevent outbreaks, must “oppose and overcome formalism and bureaucracy, and take strict and detailed measures to protect people’s life safety and health to the greatest extent, and minimize the impact of the epidemic on economic and social development,” the statement said.

    Newly reported cases of COVID-19 in China have fallen from a daily record of more than 40,000 in recent days to just 20,764 on Wednesday, the vast majority of them asymptomatic.

    Under the new measures, lockdowns can last no longer than five days unless additional cases are discovered, restrictions will be lifted on the sale of cold medications, and vaccinations for the elderly will be stepped up.

    Orders for businesses and transport companies to suspend services will be lifted and greater attention will be paid to public safety, with fire exits no longer blocked due to lockdown orders.

    The recent protests included calls for leader Xi Jinping to step down. The protests began Nov. 25 after at least 10 people died in a fire in an apartment building in Urumqi in the northwest. Authorities denied suggestions that firefighters or victims were blocked by locked doors or other anti-virus controls. But the disaster became a focus for public frustration.

    In its notice, the National Health Commission made no reference to the fire, the protests or any formal end to “zero-COVID,” which has been closely identified with Xi’s authority. The policy has kept most visitors out of China and disrupted manufacturing and global trade.

    Officials for days have been gradually rolling back restrictions.

    On Monday, commuters in Beijing and at least 16 other cities were allowed to board buses and subways without a virus test in the previous 48 hours for the first time in months.

    Industrial centers including Guangzhou near Hong Kong have reopened markets and businesses and lifted most curbs on movement while keeping restrictions on neighborhoods with infections.

    The government announced plans last week to vaccinate millions of people in their 70s and 80s, a condition for ending “zero-COVID” restrictions.

    Health experts and economists warn it will be mid-2023 and possibly 2024 before vaccination rates are high enough and hospitals are prepared to handle a possible rash of infections.

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  • China reports 2 new COVID deaths as some restrictions eased

    China reports 2 new COVID deaths as some restrictions eased

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    HONG KONG — China on Sunday reported two additional deaths from COVID-19 as some cities move cautiously to ease anti-pandemic restrictions following increasingly vocal public frustrations.

    The National Health Commission said one death was reported each in the provinces of Shandong and Sichuan. No information was given about the ages of the victims or whether they had been fully vaccinated.

    China, where the virus first was detected in late 2019 in the central city of Wuhan, is the last major country trying to stop transmission completely through quarantines, lockdowns and mass testing. Concerns over vaccination rates are believed to figure prominently in the ruling Communist Party’s determination to stick to its hard-line strategy.

    While nine in 10 Chinese have been vaccinated, only 66% of people over 80 have gotten one shot while 40% have received a booster, according to the commission. It said 86% of people over 60 are vaccinated.

    Given those figures and the fact that relatively few Chinese have been built up antibodies by being exposed to the virus, some fear millions could die if restrictions were lifted entirely.

    Yet, an outpouring of public anger appears to have prompted authorities to lift some of the more onerous restrictions, even as they say the “zero-COVID” strategy — which aims to isolate every infected person — is still in place.

    The demonstrations, the largest and most widely spread in decades, erupted Nov. 25 after a fire in an apartment building in the northwestern city of Urumqi killed at least 10 people. That set off angry questions online about whether firefighters or victims trying to escape were blocked by locked doors or other anti-virus controls. Authorities denied that, but the deaths became a focus of public frustration.

    The country saw several days of protests across cities including Shanghai and Beijing, with protesters demanding an easing of COVID-19 curbs. Some demanded Chinese President Xi Jinping step down, an extraordinary show of public dissent in a society over which the ruling Communist Party exercises near total control.

    Beijing and some other Chinese cities announced that riders can board buses and subways without a virus test for the first time in months. The requirement has led to complaints from some Beijing residents that even though the city has shut many testing stations, most public venues still require COVID-19 tests.

    On Sunday, China announced another 35,775 cases from the past 24 hours, 31,607 of which were asymptomatic, bringing its total to 336,165 with 5,235 deaths.

    While many have questioned the accuracy of the Chinese figures, they remain relatively low compared to the U.S. and other nations which are now relaxing controls and trying to live with the virus that has killed at least 6.6 million people worldwide and sickened almost 650 million.

    China still imposes mandatory quarantine for incoming travelers even as its infection numbers are low compared to its 1.4 billion population.

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  • Keep COVID military vaccine mandate, defense chief says

    Keep COVID military vaccine mandate, defense chief says

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    Secretary of Defense Lloyd Austin introduces the B-21 Raider stealth at Northrop Grumman Friday, Dec. 2, 2022, in Palmdale, Calif. America’s newest nuclear stealth bomber made its debut Friday after years of secret development and as part of the Pentagon’s answer to rising concerns over a future conflict with China. The B-21 Raider is the first new American bomber aircraft in more than 30 years. Almost every aspect of the program is classified. (AP Photo/Marcio Jose Sanchez)

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  • Beijing, Shenzhen scrap COVID-19 tests for public transport

    Beijing, Shenzhen scrap COVID-19 tests for public transport

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    BEIJING — Chinese authorities on Saturday announced a further easing of COVID-19 curbs with major cities such as Shenzhen and Beijing no longer requiring negative tests to take public transport.

    The slight relaxation of testing requirements comes even as daily virus infections reach near-record highs, and follows weekend protests across the country by residents frustrated by the rigid enforcement of anti-virus restrictions that are now entering their fourth year, even as the rest of the world has opened up.

    The southern technological manufacturing center of Shenzhen said Saturday that commuters no longer need to show a negative COVID-19 test result to use public transport or when entering pharmacies, parks and tourist attractions.

    Meanwhile, the capital Beijing said Friday that negative test results are also no longer required for public transport from Monday. However, a negative result obtained within the past 48 hours is still required to enter venues like shopping malls, which have gradually reopened with many restaurants and eateries providing takeout services.

    The requirement has led to complaints from some Beijing residents that even though the city has shut many testing stations, most public venues still require COVID-19 tests.

    The government reported 33,018 domestic infections in the past 24 hours, including 29,085 with no symptoms.

    As the rest of the world has learned to live with the virus, China remains the only major nation still sticking to a “zero-COVID” strategy which aims to isolate every infected person. The policy, which has been in place since the pandemic started, led to snap lockdowns and mass testing across the country.

    China still imposes mandatory quarantine for incoming travelers even as its infection numbers are low compared to its 1.4 billion population.

    The recent demonstrations, the largest and most widely spread in decades, erupted Nov. 25 after a fire in an apartment building in the northwestern city of Urumqi killed at least 10 people.

    That set off angry questions online about whether firefighters or victims trying to escape were blocked by locked doors or other anti-virus controls. Authorities denied that, but the deaths became a focus of public frustration.

    The country saw several days of protests across cities including Shanghai and Beijing, with protesters demanding an easing of COVID-19 curbs. Some demanded Chinese President Xi Jinping step down, an extraordinary show of public dissent in a society over which the ruling Communist Party exercises near total control.

    Xi’s government has promised to reduce the cost and disruption of controls but says it will stick with “zero COVID.” Health experts and economists expect it to stay in place at least until mid-2023 and possibly into 2024 while millions of older people are vaccinated in preparation for lifting controls that keep most visitors out of China.

    While the government has conceded some mistakes, blamed mainly on overzealous officials, criticism of government policies can result in punishment. Former NBA star Jeremy Lin, who plays for a Chinese team, was recently fined 10,000 yuan ($1,400) for criticizing conditions in team quarantine facilities, according to local media reports.

    On Friday, World Health Organization emergencies director Dr. Michael Ryan said that the U.N. agency was “pleased” to see China loosening some of its coronavirus restrictions, saying “it’s really important that governments listen to their people when the people are in pain.”

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  • Chinese vaccine plans spark hope for end of ‘zero COVID’

    Chinese vaccine plans spark hope for end of ‘zero COVID’

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    BEIJING — A campaign to vaccinate the elderly has sparked hopes China might roll back severe anti-virus controls that prompted protesters to demand President Xi Jinping resign, but the country faces daunting hurdles and up to a year of hard work before “zero COVID” can end.

    Stock markets rose after the National Health Commission on Monday announced the long-awaited campaign. A low vaccination rate is one of the biggest obstacles to ending curbs that have confined millions of people to their homes, depressed the economy and kept most visitors out of China. Health officials did not say how long it might take.

    A vaccination campaign will require months and China also needs to build up its hospitals and work out a long-term virus strategy, health experts and economists warn. They say “zero COVID” is likely to stay in place until mid-2023 and possibly as late as 2024.

    “China is in no place right now to move away from its ‘zero-COVID’ policy toward a ‘living with COVID’ policy,” said Mark Williams, chief Asia economist for Capital Economics. “Health care capacity is very weak.”

    China, where the virus first was detected in late 2019 in the central city of Wuhan, is the last major country trying to stop transmission completely. Others are relaxing controls and trying to live with the virus that has killed at least 6.6 million people worldwide and sickened almost 650 million.

    Chinese protesters accuse the ruling Communist Party of failing to outline a path away from restrictions that have repeatedly closed businesses and schools and suspended access to neighborhoods. The curbs have kept case numbers lower than other countries but are seen by the public and scientists as excessive.

    Families who have been confined at home for up to four months say they lack reliable access to food and medicine. Others struggle to get treatment for other medical problems. Authorities faced public fury over reports two children who were in quarantine died after their parents said anti-virus controls hampered efforts to get emergency medical care.

    The protests, the most widespread show of dissent in decades, erupted Friday after a fire in Urumqi in the northwest killed at least 10 people. That prompted angry questions online about whether firefighters or victims trying to escape were blocked by locked doors or other controls. Authorities denied that, but the deaths became a focus of public anger over the human cost of “zero COVID.”

    The ruling party has promised to make restrictions less disruptive and eased some controls this week following protests in Shanghai, Beijing and at least six other major cities. But party leaders said they were sticking to “zero COVID“ and gave no sign when it might end.

    On Wednesday, the Health Commission reported 37,828 new cases in the past 24 hours, including 33,540 without symptoms. The official death toll stands at 5,233 out of 319,536 confirmed cases, compared with 1.1 million deaths in the United States out of almost 100 million infections.

    Beijing has tried to discredit protesters by accusing them of working for “foreign forces,” a reference to long-running complaints that Washington and other Western governments are trying to sabotage China’s economic and political rise.

    On Tuesday, the ruling party legal affairs committee vowed to “resolutely crack down on the infiltration and sabotage activities of hostile forces.” Its statement promising to carry out the spirit of a congress last month where Xi, China’s most powerful figure since at least the 1980s, awarded himself a third five-year term as leader.

    The statement didn’t mention the protests and echoed routine declarations issued after such party meetings. But it was a reminder of the ruling party’s determination to enforce its will and of its hostility to opposition.

    The National Health Commission said its campaign will encourage people over 60 to be vaccinated.

    Many have avoided vaccines due to safety worries and because, with few cases in China, their infection risk was low.

    The commission said it will send out mobile vaccination units to reach people in their 70s and 80s who can’t leave home.

    Nine in 10 Chinese have been vaccinated but only 66% of people over 80 have gotten one shot, while 40% have received a booster shot, according to the Commission. It said 86% of people over 60 are vaccinated.

    State media have described unvaccinated elderly people as at “highest risk” from the virus.

    “We hope elderly friends can actively complete the vaccination as soon as possible,” said a commission spokesman, Mi Feng.

    China uses vaccines made by domestic developers including Sinovac and Sinopharm. It has withheld approval of mRNA vaccines such as the one invented by Germany’s BioNTech, though a Chinese company bought distribution rights in 2020.

    Last year, the country’s top infectious diseases official acknowledged those homegrown vaccines were less effective.

    Still, ahead of Tuesday’s announcement, an infectious disease expert on Shanghai’s COVID-19 team expressed confidence China can emerge from COVID with the right vaccination program.

    “Our diagnosis, treatment and vaccines have reached a very high level,” Zhang Wenhong said at a Nov. 18 medical conference in the southern city of Haikou. “We are fully capable of finally taming the coronavirus.”

    However, China’s small, overworked health care system, especially in the poor, populous countryside, could be overwhelmed if infections spiral as restrictions are relaxed.

    China has 4.3 hospital beds per person, barely half of the average of eight in neighboring Mongolia, a much poorer country, according to the World Health Organization. Japan has 13 and South Korea has 12.5.

    “China will never lift COVID restrictions completely like other countries,” said Yu Changping, a respiratory specialist at People’s Hospital of Wuhan University.

    “The epidemic will not disappear in the next three or five years and may never,” Yu said. “It is a long-term task for China’s prevention and control.”

    The outbreaks that began in October prompted affected communities to close shops and offices. Factories were required to isolate workers from outside contact.

    Economists estimate those areas account for up to one-third of China’s economic output. Some forecasts say China’s annual growth will stay below 3%, less than half of 2021′s 8.1% expansion.

    While case numbers are low, “there is definitely a risk that ‘zero COVID’ just fails at this point. It spreads rapidly everywhere,” said Williams. “I think that the response from the authorities would be to go back to the playbook from January, February 2020 and lock everywhere down.”

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  • U.S. criticizes China’s zero Covid strategy, says Beijing needs to boost vaccination among elderly

    U.S. criticizes China’s zero Covid strategy, says Beijing needs to boost vaccination among elderly

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    People hold white sheets of paper and flowers in a row as police check their IDs during a protest over coronavirus disease (COVID-19) restrictions in mainland China, during a commemoration of the victims of a fire in Urumqi, in Hong Kong, China November 28, 2022. 

    Tyrone Siu | Reuters

    The White House on Monday criticized Beijing’s zero Covid strategy as ineffective and said the Chinese people have a right to peacefully protest.

    “We’ve long said everyone has the right to peacefully protest, here in the United States and around the world. This includes in the PRC,” a spokesperson for President Joe Biden’s National Security Council said in a statement.

    Rare protests broke out against Covid lockdowns in Beijing, Shanghai, Urumqi and other cities over the weekend. Nearly three years after the virus first emerged in Wuhan, China is still imposing strict social controls to quash Covid outbreaks, while countries such as the U.S. have largely returned to normal life.

    “We’ve said that zero COVID is not a policy we pursuing here in the United States,” the NSC spokesperson said. “And as we’ve said, we think it’s going to be very difficult for the People’s Republic of China to be able to contain this virus through their zero COVID strategy.”

    The U.S. Covid response is focused on increasing vaccination rates and making testing and treatment more accessible, the spokesperson said.

    China’s stringent Covid controls have kept deaths very low compared to the U.S., but the measures have also deeply disrupted economic and social life. In China, more than 30,000 people have died from Covid since the pandemic began, according to the World Health Organization. In the U.S., more than 1 million people have died.

    Dr. Anthony Fauci, the top infectious disease expert in the U.S., said China’s approach to Covid “doesn’t make public health sense.” Vaccination rates among the elderly, one of the groups most vulnerable to Covid, are low in China compared to other countries. The vaccination campaign in China focused on people in critical positions first, those ages 18 to 59 next, and only then people ages 60 and over.

    “If you look at the prevalence of vaccinations among the elderly, that it was almost counterproductive, the people you really needed to protect were not getting protected,” Fauci told NBC’s Meet the Press on Sunday.  A temporary lockdown might make sense if the goal was to buy time to boost vaccination rates but China doesn’t seem to be doing that, he said.

    “It seems that in China, it was just a very, very strict extraordinary lockdown where you lock people in the house but without any seemingly endgame to it,” Fauci said.

    As of August, about 86% of people ages 60 and older in China were fully vaccinated and 68% had received a booster, according to a September report from China’s Center for Disease Control and Prevention. By comparison, 92% of older Americans were fully vaccinated and 70% had received a booster during that same period.

    Fauci said China’s domestically developed vaccines are also not very effective.

    The authors of the China CDC report said older people are more skeptical of the vaccine. The clinical trials didn’t enroll enough older people and as a consequence there wasn’t sufficient data on the vaccine’s safety and efficacy for this age group when the immunization campaign started, they wrote.

    Dr. Ashish Jha, head of the White House Covid task force, said China should focus on making sure the elderly get vaccinated.

    “That I think is the path out of this virus. Lockdowns and zero COVID is going to be very difficult to sustain,” Jha told ABC’s “This Week” on Sunday.

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  • Bird flu prompts slaughter of 1.8M chickens in Nebraska

    Bird flu prompts slaughter of 1.8M chickens in Nebraska

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    OMAHA, Neb. — Nebraska agriculture officials say another 1.8 million chickens must be killed after bird flu was found on a farm in the latest sign that the outbreak that has already prompted the slaughter of more than 50 million birds nationwide continues to spread.

    The Nebraska Department of Agriculture said Saturday that the state’s 13th case of bird flu was found on an egg-laying farm in northeast Nebraska’s Dixon County, about 120 miles (193 kilometers) north of Omaha, Nebraska..

    Just like on other farms where bird flu has been found this year, all the chickens on the Nebraska farm will be killed to limit the spread of the disease. The U.S. Department of Agriculture says more than 52.3 million birds in 46 states — mostly chickens and turkeys on commercial farms — have been slaughtered as part of this year’s outbreak.

    Nebraska is second only to Iowa’s 15.5 million birds killed with 6.8 million birds now affected at 13 farms.

    In most past bird flu outbreaks the virus largely died off during the summer, but this year’s version found a way to linger and started to make a resurgence this fall with more than 6 million birds killed in September.

    The virus is primarily spread by wild birds as they migrate across the country. Wild birds can often carry the disease without showing symptoms. The virus spreads through droppings or the nasal discharge of an infected bird, which can contaminate dust and soil.

    Commercial farms have taken a number of steps to prevent the virus from infecting their flocks, including requiring workers to change clothes before entering barns and sanitizing trucks as they enter the farm, but the disease can be difficult to control. Zoos have also taken precautions and closed some exhibits to protect their birds.

    Officials say there is little risk to human health from the virus because human cases are extremely rare and the infected birds aren’t allowed to enter the nation’s food supply. Plus, any viruses will be killed by properly cooking poultry to 165 degrees Fahrenheit.

    But the bird flu outbreak has contributed to the rising prices of chicken and turkey along with the soaring cost of feed and fuel.

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  • Bird flu prompts slaughter of 1.8M chickens in Nebraska

    Bird flu prompts slaughter of 1.8M chickens in Nebraska

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    OMAHA, Neb. — Nebraska agriculture officials say another 1.8 million chickens must be killed after bird flu was found on a farm in the latest sign that the outbreak that has already prompted the slaughter of more than 50 million birds nationwide continues to spread.

    The Nebraska Department of Agriculture said Saturday that the state’s 13th case of bird flu was found on an egg-laying farm in northeast Nebraska’s Dixon County, about 120 miles (193 kilometers) north of Omaha, Nebraska..

    Just like on other farms where bird flu has been found this year, all the chickens on the Nebraska farm will be killed to limit the spread of the disease. The U.S. Department of Agriculture says more than 52.3 million birds in 46 states — mostly chickens and turkeys on commercial farms — have been slaughtered as part of this year’s outbreak.

    Nebraska is second only to Iowa’s 15.5 million birds killed with 6.8 million birds now affected at 13 farms.

    In most past bird flu outbreaks the virus largely died off during the summer, but this year’s version found a way to linger and started to make a resurgence this fall with more than 6 million birds killed in September.

    The virus is primarily spread by wild birds as they migrate across the country. Wild birds can often carry the disease without showing symptoms. The virus spreads through droppings or the nasal discharge of an infected bird, which can contaminate dust and soil.

    Commercial farms have taken a number of steps to prevent the virus from infecting their flocks, including requiring workers to change clothes before entering barns and sanitizing trucks as they enter the farm, but the disease can be difficult to control. Zoos have also taken precautions and closed some exhibits to protect their birds.

    Officials say there is little risk to human health from the virus because human cases are extremely rare and the infected birds aren’t allowed to enter the nation’s food supply. Plus, any viruses will be killed by properly cooking poultry to 165 degrees Fahrenheit.

    But the bird flu outbreak has contributed to the rising prices of chicken and turkey along with the soaring cost of feed and fuel.

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  • Omicron boosters probably aren’t very effective against mild Covid illness, but will likely prevent hospitalizations, experts say

    Omicron boosters probably aren’t very effective against mild Covid illness, but will likely prevent hospitalizations, experts say

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    A healthcare worker administers a dose of the Pfizer-BioNTech Covid-19 vaccine at a vaccination clinic in the Peabody Institute Library in Peabody, Massachusetts, U.S., on Wednesday, Jan. 26, 2022.

    Vanessa Leroy | Bloomberg | Getty Images

    The new omicron Covid boosters probably aren’t very effective at preventing Covid infections and mild illness, but they will likely help keep the elderly and other vulnerable groups out of the hospital this winter, experts say.

    The Centers for Disease Control and Prevention, in a real-world study published this week, found the boosters are less than 50% effective against mild illness across almost all adult age groups when compared to people who are unvaccinated.

    For seniors, the booster was 19% effective at preventing mild illness when administered as their fourth dose, compared to the unvaccinated. It was 23% effective against mild illness when given as their fifth dose.

    Though the vaccine’s effectiveness against mild illness was low, people who received the boosters were better off than those who did not. The booster increased people’s protection against mild illness by 28% to 56% compared to those who only received the old shots, depending on age and when they received their last dose.

    The Food and Drug Administration authorized the boosters in late August with the goal of restoring the high levels of protection the vaccines demonstrated in late 2020 and early 2021. At that time, the shots were more than 90% effective against infection. But the first real-world data from the CDC indicates that the boosters aren’t meeting those high expectations.

    “The boosters give you some additional protection but it’s not that strong, and you shouldn’t rely on it as your sole protective device against infection,” said John Moore, a professor of microbiology and immunology at Weill Cornell Medical College.

    Moore said people at higher risk from Covid have every reason to get a booster since it modestly increases protection. But he said common sense measures such as masking and avoiding large crowds remain important tools for vulnerable groups since the boosters aren’t highly effective against infection.

    The CDC study looked at more than 360,000 adults with healthy immune systems who tested for Covid at retail pharmacies from September to November when omicron BA.5 was dominant. The participants received either the booster, got two or more doses of the old shots or they were unvaccinated. It then compared those who tested positive for Covid with those who did not.

    The study did not evaluate how well the boosters performed against severe disease, so it’s still unclear whether they will provide better protection against hospitalization than the old shots. The CDC in a statement said it will provide data on more severe outcomes when it becomes available.

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    Andrew Pekosz, a virologist at Johns Hopkins University, said the fact that the shots are providing some protection against infection in an era of highly immune evasive omicron subvariants is a good sign that they will provide strong protection against hospitalization. The vaccines have always performed better against severe disease than mild illness, he said.

    “It’s better than nothing. Certainly, it doesn’t sort of show that the protection is incredibly high against infection,” Pekosz said. “I would expect that you would then see even greater protection from hospitalization or death.”

    Dr. Paul Offit, a member of the FDA’s vaccine advisory committee, said trying to prevent mild illness is not a viable public health strategy because the antibodies that block infection simply wane over time.

    “Protection against mild disease just isn’t that good in the omicron subvariant era. The goal is protecting against severe disease,” said Offit, an infectious disease expert at Children’s Hospital of Philadelphia who helped develop the rotavirus vaccine.

    Dr. Celine Gounder, a senior public health fellow at the Kaiser Family Foundation, said she’s not alarmed by the data. Reducing risk by even a modest amount at the individual level can have a significant positive effect on public health at the population level.

    “If you can reduce risk among the elderly by even 30%, even 20%, that is significant when 90% of the COVID deaths are occurring in that group,” Gounder said. “For me, what’s really gonna matter is are you keeping that 65 year old out of the hospital.”

    The boosters, called bivalent vaccines, target both omicron BA.5 and the original Covid strain that first emerged in Wuhan, China in 2019. The original shots, called monovalent vaccines, only include the first Covid strain.

    It’s still unclear how the boosters will perform against more immune evasive omicron subvariants, such as BQ.1 and BQ.1.1, which are now dominant in the U.S. Pfizer and Moderna last week said early clinical trial data shows the boosters induce an immune response against these subvariants.

    About 11% of those eligible for the new booster, or 35 million people, have received it so far, according to CDC data. About 30% of seniors have received the shot.

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  • Omicron BQ Covid variants, which threaten people with compromised immune systems, are now dominant in U.S.

    Omicron BQ Covid variants, which threaten people with compromised immune systems, are now dominant in U.S.

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    A person receives a coronavirus disease (COVID-19) test as the Omicron coronavirus variant continues to spread in Manhattan, New York City, U.S., December 22, 2021.

    Andrew Kelly | Reuters

    The omicron BQ coronavirus subvariants have risen to dominance in the U.S. as people gather and travel for the Thanksgiving holiday, putting people with compromised immune systems at increased risk.

    BQ.1 and BQ.1.1 are causing 57% of new infections in the U.S., according to data published by the Centers for Disease Control and Prevention on Friday. The omicron BA.5 subvariant, once dominant, now makes up only a fifth of new Covid cases.

    The BQ subvariants are more immune evasive and likely resistant to key antibody medications, such as Evusheld and bebtelovimab, used by people with compromised immune systems, according to the National Institutes of Health. This includes organ transplant and cancer chemotherapy patients.

    There are currently no replacements for these drugs. President Joe Biden, in an October speech, told people with compromised immune systems that they should consult with their physicians and take extra precautions this winter.

    New variants may make some existing protections ineffective for the immunocompromised. Sadly, this means you may be at a special risk this winter,” Biden said.

    The XBB subvariant is also circulating at a low level right now, causing about 3% of new infections. Chief White House medical advisor Dr. Anthony Fauci, in a briefing Tuesday, said XBB is even more immune evasive than the BQ subvariants.

    Fauci, director of the National Institute of Allergy and Infectious Diseases, said the new boosters, which were designed against omicron BA.5, probably aren’t as effective against infection and mild illness from XBB. But the shots should protect against severe disease, he said. Singapore saw a spike in cases from XBB, but there wasn’t a major surge in hospitalizations, he added.

    Moderna and Pfizer said last week that their boosters induce an immune response against BQ.1.1, which is a descendent of the BA.5 subvariant.

    Fauci, in the press briefing, said public health officials believe there is enough immunity from vaccination, boosting and infection to prevent a repeat of the unprecedented Covid surge that occurred last winter when omicron first arrived.

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  • Workers protest, beaten at virus-hit Chinese iPhone factory

    Workers protest, beaten at virus-hit Chinese iPhone factory

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    BEIJING — Employees at the world’s biggest Apple iPhone factory were beaten and detained in protests over contract disputes amid anti-virus controls, according to witnesses and videos on social media Wednesday, as tensions mount over Beijing’s severe coronavirus strategy.

    Videos that said they were filmed at the factory in the central city of Zhengzhou showed thousands of people in masks facing rows of police in white protective suits with plastic riot shields. Police kicked and hit a protester with clubs after he grabbed a metal pole that had been used to strike him.

    Frustration with restrictions in areas throughout China that have closed shops and offices and confined millions of people to their homes for weeks at a time with little warning have boiled over into protests in some areas. Videos on social media show residents in some areas tearing down barricades set up to enforce neighborhood closures.

    Last month, thousands of employees walked out of the iPhone factory operated by Taiwan’s Foxconn Technology Group over complaints about unsafe working conditions following virus cases in the facility.

    A protest erupted Tuesday over complaints Foxconn changed conditions for new workers who were attracted by offers of higher pay, according to Li Sanshan, an employee.

    Li said he quit a catering job in response to advertising that promised 25,000 yuan ($3,500) for two months of work. Li, 28, said workers were angry after being told they had to work two additional months at lower pay to receive the 25,000 yuan.

    “Foxconn released very tempting recruiting offers, and workers from all parts of the country came, only to find they were being made fools of,” Li said.

    The ruling Communist Party promised this month to try to reduce disruption by shortening required quarantines and making other changes. But the party says it will stick to its “zero-COVID” strategy that aims to isolate every case at a time when other governments are relaxing travel and other restrictions and trying to live with the virus.

    Protests have flared as the number and severity of outbreaks has risen across China, including in Beijing. This week, authorities reported the country’s first COVID-19 deaths in six months.

    More than 253,000 cases have been found in the past three weeks and the daily average is increasing, the government reported Tuesday. Local leaders have responded by closing neighborhoods and imposing other restrictions that residents complain go beyond what the national government allows.

    On Wednesday, the government reported 28,883 cases found over the past 24 hours, including 26,242 with no symptoms. Henan province, where Zhengzhou is the capital, reported 851 in total.

    The government will enforce its anti-COVID policy while “resolutely overcoming the mindset of paralysis and laxity,” said a spokesman for the National Health Commission, Mi Feng.

    The capital, Beijing, has closed shops, restaurants, office buildings and some apartment compounds.

    Shanghai and the southern city of Nanchang banned people from outside the city from visiting public venues for five days after arrival.

    Foxconn said earlier the Zhengzhou factory uses “closed-loop management,” which means employees live at their workplace with no outside contact.

    The protest lasted through Wednesday morning as thousands of workers gathered outside dormitories and confronted factory security workers, according to Li.

    Other videos showed protesters spraying fire extinguishers toward police.

    A man who identified himself as the Communist Party secretary in charge of community services was shown in a video posted on the Sina Weibo social media platform urging protesters to withdraw. He assured them their demands would be met.

    Apple Inc. has warned deliveries of its new iPhone 14 model would be delayed due to anti-disease controls on the factory. The city government suspended access to an industrial zone that surrounds the factory, which Foxconn has said employs 200,000 people.

    Foxconn, headquartered in Taipei, Taiwan, didn’t respond to requests for information about the situation.

    New reports earlier said the ruling party ordered “grassroots cadres” to fill in for Foxconn employees in Zhengzhou who left. The company didn’t respond to requests for confirmation and details about that arrangement.

    ———

    Zen Soo reported from Hong Kong. AP news assistant Caroline Chen contributed.

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