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A new agreement between Biocon Biologics Ltd. and nonprofit generic drug maker Civica, Inc. is set to expand access to affordable insulin for millions of Americans living with diabetes.
The partnership, announced Wednesday, establishes a distribution deal for a private-label version of Insulin Glargine in the U.S. Under the multi-year partnership, Biocon Biologics will manufacture and supply the long-acting insulin for Civica, which will handle distribution, marketing and commercialization in the U.S. under its own label — and under the CalRx brand in California.
Biocon Biologics will continue its own direct commercialization of Insulin Glargine, complementing the Civica-labeled product to broaden access and give patients multiple ways to obtain affordable insulin.
“Biocon Biologics is committed to expanding access to affordable, high-quality insulins in the U.S. and globally,” said Shreehas Tambe, CEO and managing director of Biocon Biologics, one of the world’s largest producers of insulin, delivering more than 9.2 billion doses globally each year.
“By extending our collaboration with Civica, Inc. to include Insulin Glargine, we are building on our differentiated approach to serving and enhancing patient access—by retaining our direct commercialization and through this strategic partnership,” Tambe said. “This collaboration enables us to reach underserved populations through new channels in direct alignment with our mission.”
The new Insulin Glargine initiative builds upon the existing collaboration between the two companies. In 2025, Biocon Biologics began supplying Civica with Insulin Aspart drug substance for domestic manufacturing as part of a broader effort to address drug affordability.
Civica President and CEO Ned McCoy said the Insulin Glargine expansion brings the company closer to its mission of making essential medicines available at transparent, low prices. “We are pleased to expand our partnership with Biocon Biologics, which helps us achieve a significant milestone in our insulin initiative,” McCoy said. “Today’s announcement allows us to realize our goal of bringing insulin to people who need it at a transparent low price.”
The agreement involves no technology transfer; Biocon Biologics will retain all intellectual property and marketing authorizations for Insulin Glargine. The company’s Insulin Glargine-yfgn medicine, approved by the U.S. Food and Drug Administration in 2021 as the first interchangeable biosimilar, is used to help control blood sugar in adults and children with diabetes.
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Diabetes affects more than 38 million Americans — roughly one in nine — while another 97.6 million are estimated to have prediabetes. Rising drug costs have made insulin a focal point of U.S. health policy debates, with many patients reporting difficulty affording their prescriptions.
Civica plans to distribute its insulin glargine to pharmacies across the United States for $45 for a box of five pens, a significant discount in many cases to current prices. Civica recommends that pharmacies and health plans set a maximum recommended price for consumers of no more than $55.
“California didn’t wait for the pharmaceutical industry to do the right thing — we took matters into our own hands,” said Gov. Gavin Newsom in a statement. “By beginning the process to manufacture our own insulin and pricing it at a maximum cost of $11 a pen in a five-pack, California and Civica are showing the nation what it looks like to put people over profits. No Californian should ever have to ration insulin or go into debt to stay alive.”
McCoy said California shares the company’s vision for increasing access to affordable medicines.
“We are grateful for the support of the state of California for our effort to bring affordable insulin to all Americans,” he said. “The state shares our vision to ensure a sustainable, quality supply of affordable, essential medicines for people who need them.”
This article is intended for informational purposes only and should not be considered medical advice, diagnosis, or treatment. The information provided is based on publicly available details from the featured organizations and does not imply FDA approval or endorsement. Readers should consult a qualified healthcare professional regarding any questions or concerns about medications, treatments, or medical conditions.
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