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Tag: contraception

  • Women say birth control shot caused brain tumors—”it completely changed me”

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    Contraception is often used to prevent pregnancies and manage menstrual cycles—which is exactly why Sandra Somarakis, now 61, and Nicole Ryan, 60, chose it for over a decade.

    Both women opted for medroxyprogesterone (a type of birth control injection) called Depo-Provera, owned by Pfizer, valuing the convenience of no periods and a quick doctor’s visit every three months.

    However, both Somarakis and Ryan later developed a type of benign brain tumor called meningioma and required surgery to remove it. While these tumors are not cancerous, both women have suffered long-term side effects.

    In January, researchers from the University of British Columbia’s Faculty of Medicine reported that women who used Depo-Provera for more than a year were roughly 3.5 times more likely to develop meningiomas compared with women using other forms of hormonal birth control.

    From Routine Exam to Life-Altering Diagnosis

    According to the Centers for Disease Control and Prevention (CDC), 24.5 percent of sexually active women have used the injectable contraceptive. Sandy began using Depo-Provera in 1996, until 2010.

    Somarakis, from Oregon, told Newsweek that, during a routine mammogram in July 2008, doctors urgently summoned her back when they noticed swelling in her left eye.

    “I thought my eye was watering and sore because of hay fever,” Somarakis said. “They sent me for an MRI, and an ophthalmologist called almost immediately: they’d found a tumor in my left eye socket.

    “Within days, I was diagnosed with a meningioma,” Somarakis added.

    The following year, the tumor was removed, and Somarakis continued to use the contraception.

    “I was never told that Depo-Provera might be linked to meningiomas,” Somarakis said. She added that, 16 months later, she started suffering from severe headaches, and another tumor was found. “The neurologist was shocked,” Somarakis said.

    In January 2010, she underwent surgery to remove her second tumor, followed by six weeks of radiation. She stopped using the injection after being told that radiation would leave her infertile.

    “Radiation was horrible,” Somarakis said. “It completely changed me. I had been a 911 operator and a project manager—sharp, fast, making good money.

    “It felt like my mind was wiped. My hair started falling out; I couldn’t swallow; and, for a time, I lived on yogurt and crushed crackers with milk.

    “Even now, I’m not the person I used to be. I’ve lost many cognitive skills, and I can no longer work in the kind of high-pressure jobs I once excelled at,” Somarakis said.

    “I have tinnitus and have lost the hearing in my left ear—I’ll need a hearing aid for the rest of my life. I still get terrible headaches; it feels like my frontal lobe is about to explode. My left eye is still watery, swollen, and sometimes it pops out slightly.”

    In 2024, both Somarakis and Ryan learned of an ongoing multidistrict litigation (MDL) involving lawsuits filed against Pfizer over Depo-Provera and its alleged link to an increased risk of meningioma brain tumors.

    “When you go through something like this as a healthy person, you wonder what you did to cause it,” Somarakis told Newsweek. “I was crushed when I found out.”

    Nicole Ryan’s Symptoms and Surgery

    Ryan, who lives in California, was diagnosed in 2014 after suffering from constant lightheadedness, near fainting spells and hearing loss in her left ear.

    “I wasn’t surprised, but I was relieved to finally have confirmation of what was causing all my symptoms,” Ryan said. “Although the surgery was successful, I was left with permanent side effects such as permanent ringing in my left ear, poor balance, and headaches where the tumor was taken out.”

    Legal Action and Claims Against Pfizer

    Newsweek also spoke to Ellen Relkin, an attorney who is currently representing hundreds of women who claim they developed meningioma from Depo-Provera. The plaintiffs are seeking financial compensation and litigation has been filed in the U.S. District Court for the Northern District of Florida, Pensacola Division.

    Relkin said: “Meningioma, the majority are ‘benign’ only in the sense that they do not metastasize to other organs. But it is in the brain and can grow.

    “The brain controls sight, cognitive abilities, hearing. Clients have lost vision, some have become blind, others lost hearing.”

    Relkin is a partner at Weitz & Luxenberg and chair of the firm’s Drug & Medical Device Litigation group. She has decades of experience representing thousands of plaintiffs in pharmaceutical, medical-device, and toxic-tort cases and has served in numerous court-appointed leadership roles.

    Relkin told Newsweek about the core legal arguments: “One is failure to warn. They never warned about this risk of meningioma or to be on the lookout for the symptoms. Many of our clients had excruciating headaches or dizziness for years, and no one connected it to the drug.

    “The second is safer alternative design. Depo-Provera is extremely high dose—150 milligrams. Pfizer got approval in 2004 for a lower-dose version, Depo-SubQ Provera—104 milligrams, which is equally effective. If you can give a lower dose that’s equally effective, why give more? The dose makes the poison.”

    In the plaintiffs’ latest filing on September 22, in response to Pfizer’s attempt to have the case dismissed on federal preemption grounds, they say that Pfizer “refused to study or warn” about the risk of meningiomas for decades despite growing scientific evidence.

    They add that when the company finally requested approval for a label change it “omitted crucial information and peer-reviewed studies,” failing to give the FDA the full picture of the dangers to patients.

    Lack of Warnings in the US

    Relkin claims there aren’t warnings about meningioma. She said: “Gynaecologists and clinics don’t tell patients because it’s not in the label.

    “When women get these symptoms, doctors assume it’s something common like migraine and don’t make the causal connection. Then they keep taking the drug as the tumor grows.”

    At minimum, Relkin added that the most-serious type of warning the U.S. Food and Drug Administration (FDA) issues—known as a black-box warning—should be applied.

    “A black box would be ideal because then everyone would know. They’ll say it’s rare, but it’s not so rare—thousands of women are impacted because the drug is so widely used,” Relkin said.

    Pfizer’s Response and Listed Side Effects

    The Pfizer label highlights the following possible serious side effects of the drug. However, Somarakis and Ryan said that they were only made aware of weight gain when they opted for the injection in the late 1990s and 2000s:

    • Bone loss
    • Breast cancer
    • Blood clots and stroke
    • Ectopic pregnancy
    • Severe allergic reactions: including serious eye problems or loss of vision
    • Other health effects: may trigger migraines, depression, seizures, or liver problems.

    A Pfizer spokesperson told Newsweek: “The Company stands behind the safety and efficacy of Depo-Provera, which has been used by millions of women worldwide and remains an important treatment option for women seeking to manage their reproductive health.”

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  • Most Colorado counties lack access to aid-in-dying, abortion or gender-affirming care at hospitals

    Most Colorado counties lack access to aid-in-dying, abortion or gender-affirming care at hospitals

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    For the first time, Coloradans have a clear picture of where they can go for sometimes-controversial health services such as abortion, gender-affirming care or medical aid-in-dying.

    In much of the state, though, the answer is “nowhere close.”

    Hospitals are required to disclose data about restrictions on 66 services related to reproductive, gender-affirming and end-of-life care to the Colorado Department of Public Health and Environment under a law passed in 2023. Starting this month, they also must provide copies of their disclosure forms to patients ahead of their appointments.

    Only three Colorado counties — Denver, Douglas and Weld — have unrestricted access in at least one hospital to three services from the list that The Denver Post sampled.

    Access to gender-affirming surgery was especially limited; only 13 of Colorado’s 64 counties have a hospital without non-medical restrictions on a double mastectomy, also known as “top surgery,” for gender affirmation. (Eighteen counties have no hospital within their borders, and the rest either don’t offer mastectomies to anyone or restricted who could receive one.)

    Nor was access to the other sampled services much broader.

    Thirteen Colorado counties have a hospital that would assist with a request for medical aid-in-dying without religious or other non-medical limitations, and 15 have one that would provide comprehensive treatment for a miscarriage, which can include drugs and procedures used in induced abortions.

    Click to enlarge

    Facilities that restrict the services they offer aren’t likely to make changes because of the law — particularly since many of the restrictions stem from religious beliefs — but at least patients will know what to expect when they go for care, said Dr. Patricia Gabow, a former CEO of Denver Health who has written about the intersection of religion and health care.

    Of course, transparency only does so much for people who live in a county where the only hospitals are Catholic-owned, Gabow said. Catholic hospitals, which include those owned by CommonSpirit Health and some belonging to Intermountain Health, generally don’t offer contraception, sterilization, gender-affirming care, medical aid-in-dying or abortion.

    “People who live in Durango, I don’t know what they’re supposed to do,” she said.

    Mercy Hospital in that city follows Catholic ethical and religious directives for health care, and the closest hospital that offers comprehensive reproductive services or assistance with medical aid-in-dying is in Del Norte, about two and a half hours away.

    Catholic doctrine requires health care providers to “respect all stages of life,” and not participate in procedures such as medical aid-in-dying or sterilization without a medical reason, said Lindsay Radford, spokeswoman for CommonSpirit Health, which owns Mercy.

    The system’s hospitals work with patients and their families to provide appropriate pain and symptom relief as they near death, she said.

    “We respect and honor the physician-patient relationship, and medical decisions are made by a patient and their doctor. Patients who seek care at a CommonSpirit Health hospital or clinic are fully informed of all treatment options, including those we do not perform,” she said in a statement.

    Geographic and political differences

    Generally, access to potentially controversial services was greater in more areas with larger populations, though with significant exceptions.

    Both of Jefferson County’s hospitals, St. Anthony Hospital in Lakewood and Lutheran Hospital in Wheat Ridge, won’t allow measures to end a pregnancy if a fetus still has a heartbeat.

    The state’s form conflates “threatened” and “completed” miscarriages, said Sara Quale, spokeswoman for Intermountain Health, which owns Lutheran Hospital. The hospital doesn’t restrict care once a fetus has died, but if it still has a heartbeat, doctors attempt to treat whatever is causing the miscarriage, she said. The most common cause of miscarriages is a problem with a fetus’s chromosomes, which doesn’t allow it to survive and has no treatment.

    In contrast, people in rural Prowers County on the Eastern Plains can get comprehensive miscarriage treatment without driving elsewhere. So can residents of Rio Grande County.

    Local politics also don’t necessarily match up with access.

    The three counties that had at least one hospital offering unrestricted access to the three sampled services were deep-blue Denver and thoroughly red Weld and Douglas.

    While their residents might differ on many issues, Weld and Douglas counties shared one common characteristic with Denver: They’re home to at least one hospital owned by a secular system, such as UCHealth, Denver Health or HCA HealthOne.

    At least 22 hospitals in Colorado have religious restrictions on care options: 17 owned or formerly owned by Catholic organizations, and five affiliated with the Adventist faith. In some cases, when a hospital changes hands, provisions of the deal require the new owner to honor the seller’s religious and ethical rules, even if the buyer is secular.

    Some secular organizations also listed certain services as restricted.

    UCHealth generally doesn’t serve patients under 15, while Denver Health doesn’t provide abortions under certain circumstances because of concerns about losing federal funding, spokesman Dane Roper said.

    The seven HealthOne hospitals also had non-religious restrictions, but didn’t specify their nature. Banner Health didn’t respond to inquiries about service limitations at its five Colorado hospitals.

    Informed decision-making

    So far, Colorado is the only state that requires hospitals to directly tell patients when they don’t offer services for religious or other non-medical reasons, said Alison Gill, vice president of legal and policy with American Atheists, which supported the law as it went through the legislature.

    That provision will be important not only for Coloradans seeking care, but for people traveling to the state because of its welcoming policies around reproductive and gender-affirming care, she said.

    “We are encouraging other states to enact similar provisions because it is essential to provide patients with information about service availability so that they can make informed decisions about their health care,” she said.

    The law has some limitations, said Gabow, formerly of Denver Health. For example, an outpatient gynecology office owned by a religious health system doesn’t have to give patients the disclosure form, and insurers don’t have to include hospitals offering care without limitations in their networks, she said.

    Colorado’s law won’t inherently increase access to health care, but it may prevent surprises for patients who don’t know to look up the closest hospital’s religious affiliation or don’t realize it could affect them, said Dr. Sam Doernberg, a physician researcher at Brigham & Women’s Hospital in Boston.

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    Meg Wingerter

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  • Legal Medical Marijuana Leads To More Sex

    Legal Medical Marijuana Leads To More Sex

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    Living in a state with legal medical marijuana could mean you’re more likely to have sex, according to a study published in the Journal of Health Economics. On the surface, it might appear like a resoundingly positive finding. But researchers warn that such behavior comes with some drawbacks.

    Previous studies have demonstrated some connection between cannabis use and increased sexual activity. A 2017 study found that daily marijuana users experience 20% more sex than those who have never used cannabis. But this more recent study is among the first to focus on medical marijuana legislation and what impact that has on state residents.

    RELATED: What Is Your Marijuana Use Doing To Your Penis?

    To better understand the correlation, researchers examined states that legalized medical cannabis between 2005 and 2014. Then, they analyzed how the implementation of these laws affected sexual frequency and fertility among people in their 20s and 30. “We find that [medical marijuana laws] cause an increase in sexual activity,” the researchers concluded.

    Photo by Bloomberg Creative/Getty Images

    But the study also found medical marijuana laws lowered contraceptive use, which led to higher birth rates. More specifically, states with new medical marijuana laws saw a mean increase of 2%, translating into 333 more births per quarter. One blind spot in the study, says David Simon, co-author of the study and assistant economics at the University of Connecticut, is that researchers couldn’t determine whether these individuals were trying to get pregnant or if they just forgot to use contraception.

    “On one hand, more of these births occur to non-married partners and we find suggestive evidence of a temporary increase in gonorrhea following the passage of medical marijuana laws,” Simon told Yahoo Lifestyle. “This is consistent with a story of ‘impaired judgement.’”

    RELATED: Is It True That Marijuana Really Makes You Horny?

    However, he added, “it is also possible some of these births are due to decreases in chronic pain and increased life satisfaction.”

    Researchers also noted with the introduction of medical marijuana comes new products aimed at improving sexual wellness. Experts have split opinions on whether cannabis is a sexual aid, with some analysts pointing to high-CBD strains as increasing libido and sexual satisfaction more consistently than high-THC strains. Another study concluded cannabis resulted in higher sex drives in both men and women, while also enhancing orgasms for both sexes.

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    Brendan Bures

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  • How a medication abortion, also known as an ‘abortion pill,’ works | CNN

    How a medication abortion, also known as an ‘abortion pill,’ works | CNN

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    CNN
     — 

    While the fate of mifepristone, one of two drugs used for medication abortions, is in the hands of the US Supreme Court, the drug continues to be available in states where abortion is legal.

    “While many women obtain medication abortion from a clinic or their OB-GYN, others obtain the pills on their own to self-induce or self-manage their abortion,” said Dr. Daniel Grossman, a professor of obstetrics, gynecology and reproductive sciences at the University of California, San Francisco.

    “A growing body of research indicates that self-managed abortion is safe and effective,” he said.

    Mifepristone blocks the hormone progesterone, which is needed for a pregnancy to continue. The drug is approved to end a pregnancy through 10 weeks’ gestation, which is “70 days or less since the first day of the last menstrual period,” according to the FDA.

    In a medication abortion, a second drug, misoprostol, is taken within the next 24 to 48 hours. Misoprostol causes the uterus to contract, creating cramping and bleeding. Approved for use in other conditions, such as preventing stomach ulcers, the drug has been available at pharmacies for decades.

    Together, the two drugs are commonly known as the “abortion pill,” which is now used in more than half of the abortions in the United States, according to the Guttmacher Institute, a research group that supports abortion rights.

    “Some people do this because they cannot access a clinic — particularly in states with legal restrictions on abortion — or because they have a preference for self-care,” said Grossman, who is also the director of Advancing New Standards in Reproductive Health, a research group that evaluates the pros and cons of reproductive health policies and publishes studies on how abortion affects a woman’s health.

    READ MORE: With US Supreme Court abortion drug hearing looming, study shows how self-managed abortion became more common post-Dobbs

    What happens during a medication abortion? To find out, CNN spoke with Grossman. This conversation has been condensed and edited for clarity.

    CNN: What is the difference between a first-trimester medication abortion and a vacuum aspiration in terms of what a woman experiences?

    Dr. Daniel Grossman: A vacuum aspiration is most commonly performed under a combination of local anesthetic and oral pain medications or local anesthetic together with intravenous sedation, or what is called conscious sedation.

    An injection of local anesthetic is given to the area around the cervix, and the cervix is gently dilated or opened up. Once the cervix is opened, a small straw-like tube is inserted into the uterus, and a gentle vacuum is used to remove the pregnancy tissue. Contrary to what some say, if the procedure is done before nine weeks or so, there’s nothing in the tissue that would be recognizable as a part of an embryo.

    The aspiration procedure takes just a couple of minutes. Then the person is observed for one to two hours until any sedation has worn off. We also monitor each patient for very rare complications, such as heavy bleeding.

    A medication abortion is a more prolonged process. After taking the pills, bleeding and cramping can occur over a period of days. Bleeding is typically heaviest when the actual pregnancy is expelled, but that bleeding usually eases within a few hours. On average people continue to have some mild bleeding for about two weeks or so, which is a bit longer than after a vacuum aspiration.

    Nausea, vomiting, fever, chills, diarrhea and headache can occur after using the abortion pill, and everyone who has a successful medication abortion usually reports some pain.

    In fact, the pain of medication abortion can be quite intense. In the studies that have looked at it, the average maximum level of pain that people report is about a seven to eight out of 10, with 10 being the highest. However, people also say that the pain can be brief, peaking just as the pregnancy is being expelled.

    The level of cramping and pain can depend on the length of the pregnancy as well as whether or not someone has given birth before. For example, a medical abortion at six weeks or less gestation typically has less pain and cramping than one performed at nine weeks. People who have given birth generally have less pain.

    CNN: What can be done to help with the pain of a medication abortion?

    Grossman: There are definitely things that can be used to help with the pain. Research has shown that ibuprofen is better than acetaminophen for treating the pain of medication abortion. We typically advise people to take 600 milligrams every six hours or so as needed.

    Some people take tramadol, a narcotic analgesic, or Vicodin, which is a combination of acetaminophen and hydrocodone. Recent research I was involved in found medications like tramadol can be helpful if taken prophylactically before the pain starts.

    Another successful regimen that we studied combined ibuprofen with a nausea medicine called metoclopramide that also helped with pain. Other than ibuprofen, these medications require a prescription.

    Another study found that a TENS device, which stands for transcutaneous electrical nerve stimulator, helps with the pain of medication abortion. It works through pads put on the abdomen that stimulate the nerves through mild electrical shocks, thus interfering with the pain signals. That’s something people could get without a prescription.

    Pain can be an overlooked issue with medication abortion because, quite honestly, as clinicians, we’re not there with patients when they are in their homes going through this. But as we’ve been doing more research on people’s experiences with medication abortion, it’s become quite clear that pain control is really important. I think we need to do a better job of treating the pain and making these options available to patients.

    CNN: Are there health conditions that make the use of a medication abortion unwise?

    Grossman: Undergoing a medication abortion can be dangerous if the pregnancy is ectopic, meaning the embryo is developing outside of the uterus. It’s rare, happening in about two out of every 100 pregnancies — and it appears to be even rarer among people seeking medication abortion.

    People who have undergone previous pelvic, fallopian tube or abdominal surgery are at higher risk of an ectopic pregnancy, as are those with a history of pelvic inflammatory disease. Certain sexually transmitted infections can raise risk, as does smoking, a history of infertility and use of infertility treatments such as in vitro fertilization (IVF).

    If a person is on anticoagulant or blood thinning drugs or has a bleeding disorder, a medication abortion is not advised. The long-term use of steroids is another contraindication for using the abortion pill.

    Anyone using an intrauterine device, or IUD, must have it removed before taking mifepristone because it may be partially expelled during the process, which can be painful.

    People with chronic adrenal failure or who have inherited a rare disorder called porphyria are not good candidates.

    CNN: Are there any signs of trouble a woman should watch for after undergoing a medication abortion?

    Grossman: It can be common to have a low-grade fever in the first few hours after taking misoprostol, the second drug in a medication abortion. If someone has a low-grade fever — 100.4 degrees to 101 degrees Fahrenheit — that lasts more than four hours, or has a high fever of over 101 degrees Fahrenheit after taking the medications, they do need to be evaluated by a health care provider.

    Heavy bleeding, which would be soaking two or more thick full-size pads an hour for two consecutive hours, or a foul-smelling vaginal discharge should be evaluated as well.

    One of the warning signs of an ectopic pregnancy is severe pelvic pain, particularly on one side of the abdomen. The pain can also radiate to the back. Another sign is getting dizzy or fainting, which could indicate internal bleeding. These are all very rare complications, but it’s wise to be on the lookout.

    We usually recommend that someone having a medication abortion have someone with them during the first 24 hours after taking misoprostol or until the pregnancy has passed. Many people specifically choose to have a medication abortion because they can be surrounded by a partner, family or friends.

    Most people know that the abortion is complete because they stop feeling pregnant, and symptoms such as nausea and breast tenderness disappear, usually within a week of passing the pregnancy. A home urine pregnancy test may remain positive even four to five weeks after a successful medication abortion, just because it takes that long for the pregnancy hormone to disappear from the bloodstream.

    If someone still feels pregnant, isn’t sure if the pregnancy fully passed or has a positive pregnancy test five weeks after taking mifepristone, they need to be evaluated by a clinician.

    People should know that they can ovulate as soon as two weeks after a medication abortion. Most birth control options can be started immediately after a medication abortion.

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  • “Did my pill cause cancer?” Women describe how the pill changed their lives

    “Did my pill cause cancer?” Women describe how the pill changed their lives

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    About 150 million women around the world take the pill, mostly for birth control but also to regulate periods or reduce acne.

    The combined (estrogen and progesterone) pill and progesterone-only pill are more than 90 percent effective as birth control, according to the Centers for Disease Control and Prevention.

    Millions of women take the tablets without any issues, but some experience serious physical and mental side-effects. Newsweek contacted pill users in North America, Europe and Australia to find out more.

    One woman in the U.S., who did not want to be named, told Newsweek her personality changed so drastically that she had to be assessed for borderline personality disorder.

    Clockwise from top left: Sarah Graham, Rylie Lane and Kira Holli. All three women spoke to Newsweek about how the pill affected them.

    Another woman, who also did not want to be named, said the two weeks she spent on the pill were among the worst of her life. “I was depressed and I wanted to beat my husband up,” she said. “I was so depressed and angry. It really messed up my hormones.”

    Side-effects and risks

    The Government Office on Women’s Health states that the combined pill, first approved in 1960, can have side-effects including headaches, upset stomachs, sore breasts, period changes, mood changes, weight gain and high blood pressure. “Less common but serious risks include blood clots, stroke and heart attack; the risk is higher in smokers and women older than 35,” it adds.

    The progesterone-only tablet, or mini-pill, can have side-effects including irregular, weight gain, sore breasts, headaches and nausea, according to the office, which is part of the Department of Health and Human Services.

    Below, Newsweek talks to four women about how their years on the pill affected them—and to doctors about how common their experiences are.

    Struggling To Get Pregnant After Coming Off Pill

    Jane Jones (not her real name) was 15 when her doctor prescribed the pill. “I was experiencing painful ovarian cysts. My doctor had told me that going on the pill would reduce them,” she told Newsweek.

    Jones, now 45 and boss of a PR consulting firm in Washington, was on the pill until she was 29, despite “frequent mood swings and terrible headaches before my cycle each month.”

    She stopped taking it, but her periods stopped too. Many women find it can take a few months for their cycles to “reset.” For Jones, this lasted a few years, a condition known as post-pill amenorrhea.

    “This lack of cycle went on for a while before I realized anything was wrong,” she said. “At first, I was relieved not to have the headaches often or at all, which is why I didn’t talk to my doctor right away.”

    By her early thirties, she wanted to start a family. Her obstetrician-gynecologist said she should consult an endocrinologist to find out why she wasn’t ovulating.

    Post-pill amenorrhea can be related to problems with the thyroid, polycystic ovary syndrome (PCOS), primary ovarian insufficiency, stress and even over-exercise.

    Jones said: “My doctor told me it was likely as a result of my cycle not regulating on its own after being on birth control. Ironically, the first thing they did was put me back on birth control to restart my cycle. It worked to reset everything.”

    After this, she “spent about eight years in and out of fertility treatment.” The headaches returned even worse than before, as she was having extra hormone injections.

    “I recall feeling overwhelmed and unsure,” she said. Fertility treatment “was very hard on me and those around me.”

    The treatment worked and Jones is now a mom of two. She argues that although the pill helps regulate menstrual cycles, the side-effects are “not fun. If I had the choice in taking the pill or not taking it again, I would not.”

    Newsweek asked Dr. Semiya Aziz, a general practitioner in London, about the pill and fertility. She said: “Contrary to many women’s beliefs, using hormonal birth control does not affect the woman’s ability to have a baby in the future.”

    Aziz, who also gives health advice on the British TV show This Morning, pointed out that the pill could actually disguise problems that do affect fertility, such as irregular periods, PCOS and endometriosis.

    ‘I Asked the Doctor, Did the Pill Cause the Cancer?’

    Sarah Graham, who lives in Liverpool, U.K., was diagnosed with stage 3 breast cancer in 2021 when she was just 26, after she found a lump while checking her breasts in the shower.

    She had a lumpectomy, plus 16 rounds of chemotherapy and 21 rounds of radiotherapy. Now 28 and cancer free, Graham believes her illness was down to being on the pill for 10 years.

    “I had no family history of cancer at all. I had multiple genetic screenings which all came back negative, showing no new mutations. It was basically potluck,” she told Newsweek.

    “They say that your chance of getting cancer is also defined by environmental factors, but my sister has never had it and we grew up together.”

    She added: “When I was diagnosed, the first thing I was told was that I need to stop taking the pill because it contains hormones that will continue to feed the cancer. If I gave my body any more, it would just eat it up and make the cancer spread.”

    Graham had taken the combined pill for seven years and the mini-pill for three, without any breaks. She had switched to the mini-pill because the combined tablet was giving her migraines.

    After her diagnosis, she asked her doctor whether the pill had played a role, but the physician evaded her question and Graham was left feeling that the topic was “taboo.”

    “I asked the doctor, did the pill cause the cancer? She just said that we can’t say yes, but I’ve got no family history of cancer, I’m so young and the only thing that I’d taken was this contraception,” she said.

    Graham now talks about her experiences on social media to alert other women. “I feel like doctors offer us the pill so flippantly, because it helps with acne and heavy periods as well as protecting against pregnancy, but you should be told about the breast cancer risk.

    “You should be given an informed talk, and you should be told to start checking for lumps. I probably wouldn’t be here, or I’d be in a worse state, if I didn’t check.”

    Scientific research has found the combined pill can increase the risk of breast and cervical cancer and, in March this year, University of Oxford scientists reported a similar “slight increase in breast cancer risk” linked to the mini-pill.

    The National Cancer Institute (NCI) states that “an analysis of data from more than 150,000 women” who had participated in 54 studies showed that women who had used oral contraceptives had a 7 percent increased risk of breast cancer while women who were currently using oral contraceptives had a 24 percent higher risk.

    This risk declines once the user has stopped taking the pill. “No risk increase was evident by 10 years after use had stopped,” according to the institute.

    The NCI also points out that studies have found “the risks of endometrial, ovarian and colorectal cancers are reduced” in woman taking the pill.

    Aziz pointed out that the reduced risk of ovarian cancer was particularly apparent in women who carry the harmful mutation BRCA1 and BRCA2 genes.

    She added that most of the studies on cancer risk are observational and “unable to definitively establish the fact that exposure to the oral contraceptive may cause or prevent cancer.”

    This is because women who take the pill may differ from those who don’t in many ways—and those other differences could explain the varying cancer risk.

    Three Women Speak Out About The Pill
    Stock image of contraceptive pills on a pharmacy counter. The combined pill was first approved by the U.S. Food and Drug Administration in 1960.
    Getty

    ‘I Could Have Had So Much More Out of Life’

    Rylie Lane is a health and mindset coach based in Melbourne, Australia. The 27-year-old was prescribed the combined pill at 18 and stayed on it for almost nine years.

    “I experienced cystic acne, mood changes, depression, anxiety, gut health issues and out-of-character reactions,” Lane told Newsweek.

    “Within the first few weeks of being off the pill, I felt like a normal person again. I had so much energy and full enjoyment in life. It really felt like my real personality had been repressed for years.”

    She added that she’d tried “many different things” to lift and regulate her mood, to no avail.

    Looking back, she said, “I know that coming off the pill would have fixed those problems, but back then there was no education about what the pill could do to your body. I could have had so much more out of life over those years.”

    She added: “The pill shouldn’t be the default mode of contraception that we’re offered.”

    ‘I Became Really Sad and Really Argumentative’

    Kira Holli, 20, had a similar experience to Lane on the combined pill. The production assistant from Manchester, north-west England, took it for nine months between September 2020 and June 2021, before her partner pointed out how much she had changed.

    “I became really sad and really argumentative too. I’m lucky, though. I feel we caught what it was doing to me early,” Holli told Newsweek.

    She’s now scared to go back on any type of hormonal contraception, for fear it could have the same effects despite the different brand names.

    Dr. Nathan Goodyear, medical director at Brio Medical in Arizona, told Newsweek that hormonal “contraception and mood disruptions” go hand in hand.

    Although many women who stop taking the pill do so “due to intolerable side-effects such as changes in mood,” as Aziz put it, the evidence on the link is mixed.

    A review of research studies, published in 2016, said it was “difficult to make strong conclusions about which CHC [combined hormonal contraception] users are at risk for adverse mood effects. Until more prospective data is available, clinicians should recognise that such effects are infrequent.”

    A study of more than 1 million women in Denmark, published in November 2016, suggested adolescents who were prescribed the pill had a higher risk of developing depression, and a Swedish study this year reported similar results.

    Writing about the Danish research on the Harvard Health Blog, Dr. Monique Tello said: “Should we stop prescribing hormonal birth control? No. It’s important to note that while the risk of depression among women using hormonal forms of birth control was clearly increased, the overall number of women affected was small.”

    She added: “I plan to discuss this possibility with every patient when I’m counseling them about birth control, just as I would about increased risk of blood clots and, for certain women, breast cancer. In the end, every medication has potential risks and benefits.”

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