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Tag: chimera

  • Style Meets Strategy in Songs of Silence on Sale at 50% off This Week – Xbox Wire

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    Immerse yourself in the fractured and magical world of Songs of Silence this October during the DGP Xbox Sale, where you will be able to get the game at a 50% discount!

    Songs of Silence is a story-rich 4x strategy game with fast-paced campaigns, dynamic battles and stunning Art Nouveau visuals where the players manage kingdoms and command armies as they explore a world torn by conflict and sundered into realms of light and darkness. Follow the main story of the campaign through the eyes of Lorelei as she fights to save her people and from the dangers that lurk around the world. You can manage armies and cities and conquer your rival kingdoms in both single and multiplayer skirmishes. The game uses beautifully crafted Cards of Fate as the actions a player can take in a battle where powerful abilities and magical powers can turn the tide of battle at any moment. The game’s aesthetic is a beautiful, hand drawn, Art Nouveau style that emphasizes the beauty and awe of a fantasy universe full of magic and otherworldly creatures, inspired by great artists like Alphonse Mucha, Belle Époque and Gustav Klimt.

    Songs of Silence screenshot

    The game’s simple yet engaging battle system makes transition between narrative and gameplay effortless. The musical prowess of Hitoshi Sakimoto accompanies every step of the way, through cinematics, campaigns and battles with an incredible soundtrack. The music merges with the sound effects in a harmonious mixing of both intense battle sounds and dialogue.

    Songs of Silence screenshot

    Our dev team is constantly working on the game, resulting in regular updates and new content. We are always open to new ideas and love hearing from our community. We believe that focusing on our core players will yield the best results in fixing any issues that may arise and making our fans proud. The team truly prides itself on the amazing visuals the game has to offer as well as the strategic yet uncomplicated battle system and the strong narrative the game has to offer. We want to take this opportunity to push the potential of the game’s outreach. We believe that through constant work on the development of new content and the regular engagement with our community we will be able to cater to a bigger audience and expand the magical universe of Songs of Silence even more. Meta: Details on the soundtrack and visual inspirations for the player-inspired game on sale today.


    Songs of Silence

    Songs of Silence

    Chimera Entertainment


    ☆☆☆☆☆
    22


    ★★★★★


    $29.99


    Songs of Silence is a fantasy strategy title which marries deep, tactical gameplay with fast-paced autobattles and an engaging, compelling narrative. Presented in a unique graphical style derived from the Art Nouveau movement, Songs of Silence is a beautiful example of the evolution of a classic genre. The game features an extensive singleplayer, narrative-driven campaign, plus multiple competitive and cooperative multiplayer modes for endless replay value.

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  • WTF Fun Fact 13613 – First Chimeric Monkey

    WTF Fun Fact 13613 – First Chimeric Monkey

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    Researchers have made a monumental stride in primate research by making the first chimeric monkey.

    This marks the first successful birth of a chimeric monkey from embryonic stem cell lines. This scientific achievement has profound implications for the fields of genetic engineering, species conservation, and biomedical studies.

    Understanding Chimerism in Primates

    The study, led by senior author Zhen Liu of the Chinese Academy of Sciences, culminated in the birth of a monkey with cells originating from two distinct embryos. Until now, this feat of chimerism had been achieved only in smaller mammals such as rats and mice. Published in the prestigious journal Cell, the research opens new avenues for understanding pluripotency. That’s the capability of stem cells to differentiate into any cell type—in non-human primates and possibly humans.

    The cynomolgus monkeys, commonly used in biomedical research, served as the subjects for this groundbreaking experiment. The researchers established nine stem cell lines from blastocyst embryos and selected a subset of these pluripotent cells to inject into early-stage monkey embryos. This meticulous process led to several pregnancies and the birth of six live monkeys. One of these showcased a substantial level of chimerism.

    The Making of a Chimeric Monkey

    The researchers tagged the stem cells with green fluorescent protein. This enabled them to trace which tissues originated from the stem cells. Extensive analysis revealed that the chimeric monkey exhibited a wide distribution of stem-cell-derived tissues across the brain, heart, kidney, liver, and gastrointestinal tract. Remarkably, the live monkey displayed stem cell contributions ranging from 21% to 92% across various tissues, averaging 67%.

    The presence of stem-cell-derived cells in the reproductive tissues was a significant discovery. It underscors the potential for these cells to contribute to the germline and possibly influence future generations.

    Implications and Future Directions

    The success of this study is not merely academic. It has practical implications, offering the potential to create more precise monkey models for neurological and other biomedical research. By enhancing the understanding of primate cell developmental potential, the study paves the way for innovative approaches in medical science.

    Looking ahead, the team aims to refine their method to increase the efficiency of generating chimeric monkeys. They plan to optimize the stem cell cultures and the blastocysts’ environments, hoping to improve the survival rates of these embryos in host animals.

    In conclusion, the birth of the first chimeric monkey from embryonic stem cells is a remarkable scientific milestone. It broadens our knowledge of primate biology and holds promise for future applications that could benefit both primate conservation and human health.

    — WTF fun facts

    Source: “First live birth of a chimeric monkey using embryonic stem cell lines” — ScienceDaily

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