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Tag: Chemistry

  • Supermom In Training: My favourite natural cleaners

    Supermom In Training: My favourite natural cleaners

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    When I got pregnant 10 years ago, I suddenly found myself reevaluating everything about my lifestyle- what I ate, what I drank, and how I cleaned my house. I love a clean, disinfected house, but I was very leery of all the chemicals, especially now that I was incubating this little human.

    So here are a few of my favourite natural cleaners that work just as well as their chemical-laden counterparts.

    Vinegar. Vinegar is an amazing thing. It’s fantastic for streak-free windows and mirrors, and despite the initial smell, it doesn’t linger. It disinfects too. I clean my bathroom and kitchen counter surfaces with it. I also boil a cup of water and a tablespoon of vinegar in the microwave, then it wipes down super easily.

    Homemade dryer sheets. Mix 1/2 cup vinegar with 2-3 drops of your favourite essential oils in a jar. Throw in 4-5 fabric scraps, then when needed, wring them out and throw them into the dryer with your wet, clean clothes. The vinegar naturally takes away the static cling, and the essential oil will make your laundry smell just as fresh as dryer sheets or fabric softener (without all the man-made crud).

    Baking soda. Toss those abrasive cleaners into the garbage and instead opt for a box of baking soda. Cheaper and just as effective, it will clean soap scum in the tub, remove build-up in the sink, and will get taps super shiny clean. You can also use baking soda as a natural alternative to toothpaste.

    Olive oil. Get rid of those cans of furniture polish, which are filled with unhealthy chemicals, and instead get a beautiful sheen on furniture with a drop of olive oil and a soft rag. Or, mix some olive oil, raw sugar and a few drops of essential oils for a natural body scrub.

    Fruit peels. Don’t throw out those apple and orange peels – put them into a pot with some water and your favourite spices (cinnamon, nutmeg, cloves, thyme, etc.), and simmer. You’ll get the aromatic benefits and it will also add some much-needed humidity to the air, especially in winter.

    – Jennifer Cox

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  • Capital City Sunday: GOP medical marijuana proposal, Wisconsinites’ tax burden still near historic low | News – Medical Marijuana Program Connection

    Capital City Sunday: GOP medical marijuana proposal, Wisconsinites’ tax burden still near historic low | News – Medical Marijuana Program Connection

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    MADISON (WKOW) — Wisconsin Repubicans have unveiled a new proposal to establish a medical marijuana program in the state.

    The bill would limit the drug to only those who are severely ill with chronic diseases like cancer. Smokeable marijuana would not be allowed.

    The proposal also regulates medical cannabis growers, processors, and testing laboratories, and requires the state to establish five state-owned dispensaries to grow and sell medical cannabis products.

    Cannabis lawyer Jason Tarasek worked closely with lawmakers in Minnesota to hone the state’s adult-use cannabis bill that legalized recreational marijuana in the state. He said this week that he sees similarities between Wisconsin’s proposal and Minnesota’s initial medical marijuana program that was established in 2014. Assembly Speaker Robin Vos has indicated this proposal is based on Minnesota’s program.

    Tarasek said that their initial program was similarly restrictive, but has loosened in recent years to include other conditions such as autism, intractable pain, and sleep apnea. 

    “Like everything with marijuana, it is very controversial when it’s first introduced, the stigma is real around marijuana,” he said. “I think it’s interesting to watch these states come online, and I’m certain that if the medical marijuana program is introduced in Wisconsin, as intended, society will see this…

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    MMP News Author

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  • Korean Artificial Sun, KSTAR, Installation of a tungsten divertor for long pulse operations

    Korean Artificial Sun, KSTAR, Installation of a tungsten divertor for long pulse operations

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    Newswise — The Korean artificial sun, KSTAR, has completed divertor upgrades, allowing it to operate for extended periods sustaining high-temperature plasma over the 100 million degrees.

    The Korea Institute of Fusion Energy announced the successful installation of the newly developed tungsten divertor for KSTAR. KSTAR, now equipped with the new divertor, commenced a plasma experiment on the 21st of December 2023.

    The divertor, a crucial plasma-facing component installed at the bottom of the vacuum vessel in a magnetic fusion device known as a Tokamak, manages the exhaust of waste gas and impurities from the reactor and also endures the highest surface heat loads. This is why it is important to develop and deploy a divertor that is highly heat-resistant.

    Initially, KSTAR had a carbon divertor, but for KSTAR’s enhanced performance and prolonged operations at 100 million ℃, the heat flux exceeded the limit of the carbon divertor.

    Consequently, the development of a divertor using tunsten has begun in 2018. The first prototype was completed in 2021, and installation of a new divertor took place from September 2022 for approximately one year. The recently installed divertor consists of 64 cassettes, each crafted from tungsten mono-blocks. These 64 cassettes fully surround the bottom of the vacuum vessel.

    Tungsten material possesses a high melting point and low sputtering characteristics. Therefore, the heat flux limit has improved by over two-fold compared to the carbon divertor, reaching 10 MW/m².

    The plasma experiments of KSTAR in the new tungsten divertor environment will continue until February 2024. The primary objectives include verifying stable operations in the new tungsten divertor environment and reproducing KSTAR’s 100-million-degree plasma.

    KFE President, Dr. Suk Jae Yoo stated, “In KSTAR, we have implemented a divertor with tungsten material which is also the choice made in ITER. We will strive to contribute our best efforts in obtaining the necessary data for ITER through KSTAR experiments.”

    Previously, KSTAR has demonstrated high performance plasma operation for 30 seconds with an ion temperatures over 100 million degrees, and now the goal is to achieve 300 seconds by the end of 2026 with this new divertor.

     

    ###

    The Korea Institute of Fusion Energy(KFE) is Korea’s only research institute specializing in nuclear fusion. Based on our development and operation of KSTAR, a superconducting fusion research device, the KFE seeks to achieve groundbreaking research results, develop core technology for commercializing nuclear fusion, and train outstanding nuclear fusion personnel. In addition, the institute is spearheading a joint effort to open the era of nuclear fusion energy in the mid-21st century through active participation in the ITER Project.

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    National Research Council of Science and Technology

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  • Scientists Probe the Emergent Structure of the Carbon Nucleus

    Scientists Probe the Emergent Structure of the Carbon Nucleus

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    The Science

    Newswise — The element carbon is critical to organic chemistry and life as we know it. The physics of its most common isotope, carbon-12, are extremely complex. Many experimental and theoretical investigations have been devoted to determining the energies and underlying structures of the nuclear states of carbon-12. In this work, researchers computed these states from first principles—the most basic components of physics theory. The approach used supercomputers and nuclear lattice simulations to calculate the three-dimensional shape formed by the protons and neutrons comprising the nucleus. The results show that all of the low-lying energy states of carbon-12 have a substructure where the six protons and six neutrons cluster together into alpha particles. Alpha particles are helium-4 nuclei, which contain two protons and two neutrons.

    The Impact

    One well-known nuclear state of carbon-12 is the Hoyle state. This state has an energy that sits near the energy threshold for three alpha particles or helium nuclei. This energy thereby greatly enhances the production of carbon in helium-burning stars. This helps to explain the presence of carbon in the Universe. The results obtained in this research show that the Hoyle state is composed of a “bent arm” or obtuse triangular arrangement of alpha particles. All the low-lying energy states of carbon-12 have an intrinsic shape composed of three alpha particles forming either an equilateral triangle or an obtuse triangle. The new results give information about the possible geometrical shapes of nuclear states.

    Summary

    The carbon atom provides the backbone for the complex organic chemistry composing the building blocks of life. The physics of the carbon nucleus in its predominant isotope, carbon-12, are also full of complexity. Researchers from the University of Bonn, Forschungszentrum Jülich in Germany, the Gaziantep Islamic Science and Technology University in Turkey, the Graduate School of China Academy of Engineering Physics, Tbilisi State University, and the Facility for Rare Isotope Beams at Michigan State University calculated the structure of the nuclear states of carbon-12 using the ab initio framework of nuclear lattice effective field theory.

    The research found that all the low-lying states of carbon-12 have an intrinsic shape composed of three alpha clusters forming either an equilateral triangle or an obtuse triangle. The states with the equilateral triangle shape also have a dual description in terms of particle-hole excitations in a mean-field picture. The results agree with experimental data and provide the first model-independent density map of the nuclear states of carbon-12. The results help to explain the origins of carbon from the helium and hydrogen that made up the Universe shortly after the Big Bang.

    Funding

    This research was funded by the Deutsche Forschungsgemeinschaft (the German Research Foundation), the National Natural Science Foundation of China , the Chinese Academy of Sciences President’s International Fellowship Initiative, the National Security Academic Fund of China, Volkswagen Stiftung, the European Research Council, the Department of Energy, and the Nuclear Computational Low-Energy Initiative SciDAC-4 project, as well as computational resources provided by the Gauss Centre for Supercomputing e.V. and the Oak Ridge Leadership Computing Facility.


    Journal Link: Nature Communications, May-2023

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    Department of Energy, Office of Science

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  • Lawmakers may revisit issue of drivers smelling of marijuana | Police Fire Court – Medical Marijuana Program Connection

    Lawmakers may revisit issue of drivers smelling of marijuana | Police Fire Court – Medical Marijuana Program Connection

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    When leaving a meeting at Prince George’s Community College on the night of Dec. 12, the Rev. Robert L. Screen and his wife were shocked when a car drove past them smelling so strongly of marijuana that they both noticed it even with their windows rolled up.

    The couple had just left the MD Route 210 Traffic Safety Committee, an organization that Screen founded, when the car drove past. Screen carefully put some distance between him and the other car, as it sped off down the road.


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    MMP News Author

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  • Gift Guide 2023: Beauty products for everyone on your wish list

    Gift Guide 2023: Beauty products for everyone on your wish list

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    This holiday season, help everyone on your gift-buying list put their best faces forward with these great ideas.

    From the Immortelle Divine Collection for your mom to the Grooming Collection for your favourite brother, L’Occitane has something for everyone. Even for your kids’ teachers, indeed we are sure they will like the Hand Cream Holiday Classics or the Travel Sets. They’re pretty much ready-to-go presents for everybody to enjoy and pamper themselves.

    Know someone who colours their hair? Then get them Function of Beauty PRO’s patented Adaptive f3 Bonding Complex. The changing of seasons is a favourite excuse for a fresh look, but less loved is the damage that comes with the new ‘do. This product offers healthy and on-trend hair that targets hair’s unique damage to relink broken hair bonds (with damage resulting from hair colouring included!).

    BKIND recently launched two limited-edition holiday nail polish sets. These collections contain festive and trendy colors for the holiday season: the Festives – Nail Polish Collection offers a beautiful selection of three festive and glamorous colours. You will find En Beau Fusil, a rich and velvety forest green, French Beige, a soft and delicate beige, and 24K, a transparent polish filled with golden shimmers. The Holiday Essentials – Nail Polish Collection is made up of three classic colours for the holiday season. In this set, you will find Bichon, an opaque white, pure as snow, Glacial, a silvery gray, and Leo, a classic rich red.

    When you don’t know what to get the beauty lover in your life, wrap up Slipssy, a pillow cover system made with GlideTex technology that helps prevent sleep wrinkles, bedhead, and hair loss, releasing up to 80% of facial tensions. With its double layer system, the Slipssy fits perfectly under a regular pillowcase, elevating their nightly routine with a touch of elegance, simplicity and comfort. 

    There’s a flavour for absolutely everyone with Hooker Lips glosses and balms. Think: buttercream frosting, fried bacon, dill pickle (one of their best sellers!), and so many more. All ingredients in Hooker Lips are paraben-free, petroleum-free, and BHA-free. 

    Give the gift of stronger, and healthier hair this season with The Strength Cure Holiday Ornament set from Pureology. Miniature travel sized versions of their strength-building products are perfect as a stocking stuffer!

    The Holiday Limited Edition Sky High Mascara Makeup Gift Set from Maybelline is the perfect gift for the lash enthusiast on your list. From volumizing wonders to lengthening miracles, Maybelline New York’s Sky High Mascara and Primer will ensure lashes are the star of every holiday gathering. It’s the ideal present for the beauty lover in your life, or perhaps a little indulgence to keep for yourself and make your lashes the talk of the town.

    The Makeup Essentials Gift Set from L’Oreal features the Le Khôl Eyeliner that can be easily applied with its pencil tip, the Voluminous Mascara for a lash look with classic volume, and the Colour Riche Lipstick in share Fairest Nude. These gift sets are so good that you’ll be stocking up on two of each — one for you and one for your best friend, of course! 

    Beauty lovers will rejoice over the gift sets from the clinical skincare brand Peter Thomas Roth. The Gift of Bright Eyes is a limited-edition three-piece kit of full-size bestselling Hydra-Gel Eye Patches helps lift, firm, and hydrate the look of the face and eye area. It includes 24K Gold Pure Luxury Lift & Firm Hydra-Gel Patches, FIRMx® Collagen Hydra-Gel Face & Eye Patches, and Water Drench® Hyaluronic Cloud Hydra-Gel Eye Patches.

    NYX makes it easy to sleigh the holidays with the NYX Professional Makeup Holiday gift sets. Their wide range of holiday gift sets includes everything from primer sets to lip sets, with year-round favourites along with special holiday items and even a few surprises.

    For the ultimate beauty destination, get a gift certificate to MAKA. All MAKA beauty, aromatherapy, and perfume products are formulated and manufactured on-site in the workshop adjoining the boutique. MAKA offers high-quality and innovative vegan products, while being respectful of the planet.

    If you’re buying for someone who has a penchant for skincare, then get them a gift set from The Ordinary. They have a wide range of collections for skincare, haircare, and more, all beautifully packaged and ready to give.

    Burt’s Bees puts soft skin first, and this holiday season, they have slews of festive gift sets, like their Mistletoe Kiss gift set, the Hand Cream Trio Holiday Gift Set, and lots of others. Get one for everyone on your list.

    There is no hassle to replenish skincare products with Blair + Jack! Blair + Jack offer a subscription service so there’s no worrying about running out of skincare products. On a monthly basis, Blair + Jack will send all the products needed to keep your skin looking its best. There’s also a 10% discount by signing up for the Subscription Service at checkout.

    The Body Shop makes holiday gifting a breeze with gift sets for everyone on your list. The Body Shop Cherries and Cheer Gift sets are packed with The Body Shop limited edition warm and juicy body care. The Unwind and Rest Sleep Intro Gift set is crafted with a blend of lavender and vetiver essential oils to relax the body and mind before bedtime. Finally, The Body Shop’s Slather and Lather Body Butter Gift Set has five of their bestselling body butters.

    – JC

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  • GoldieBlox and Discovery Education Partner to Bring Chemistry to High School Classrooms Nationwide with New Immersive Learning Experience on Roblox 

    GoldieBlox and Discovery Education Partner to Bring Chemistry to High School Classrooms Nationwide with New Immersive Learning Experience on Roblox 

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    Charlotte, NC – GoldieBlox and Discovery Education today announced a new education initiative – Maker High. Maker High offers an immersive learning experience hosted on Roblox for educators to teach chemistry in middle and high school classrooms.   

    Maker High is a new experience on Roblox from the award-winning GoldieBlox team that leverages the power of gamified learning to deeply engage learners in chemistry. Maker High features Chem Lab Escape, a virtual escape room set in a chemistry lab where high school students explore core concepts of chemistry through dynamic gameplay. Chem Lab Escape empowers students to solve challenges such as combining elements and solutions to create chemical reactions and adding and removing heat energy to water to navigate an obstacle course. Accompanying student-driven activities and hands-on investigations are aligned with the Next Generation Science Standards and facilitate instruction around particle motion and the types of chemical reactions. Resources from Maker High, including the Chem Lab Escape, pair digital media with easy-to-follow instructions and are simple to incorporate into any lesson plan and learning environment.  

    “GoldieBlox has over a decade’s worth of experience making STEM fun and inclusive, especially for girls who have been traditionally excluded from STEM fields. Maker High empowers students to understand and master STEM concepts. Maker High makes learning fun by meeting students where they already are: on Roblox. Every detail of these resources are thoughtfully designed to strike that hard-to-reach balance of entertainment and academic rigor, all while delivering the learning content in an accessible, inclusive way,” said Debbie Sterling, CEO and Founder of GoldieBlox. “We hope teachers and students come back to play again and again to build upon their STEM skills.” 

    GoldieBlox is a Roblox Community Fund (RCF) grantee. Established in 2021, RCF offers grants to educational organizations and developers to enable the creation of innovative learning experiences and curriculum leveraging the platform in immersive and compelling ways. 

    Learn more about Maker High at makerhigh.discoveryeducation.com or within Discovery Education Experience, the award-winning K-12 learning platform. Connecting educators to a vast collection of high-quality, standards-aligned content, ready-to-use digital lessons, intuitive quiz and activity creation tools, and professional learning resources, Discovery Education provides educators with an enhanced learning platform that facilitates engaging, daily instruction. 

    “Research shows that game-based learning proves an effective teaching tool in an educator’s toolbox. We’re proud to team up with GoldieBlox to bring chemistry to life through Maker High on Roblox,” said Amy Nakamoto, General Manager of Social Impact at Discovery Education. 

    For more information about Discovery Education’s award-winning digital resources and professional learning solutions visit www.discoveryeducation.com, and stay connected with Discovery Education on social media through X (formerly Twitter), LinkedIn, Instagram, TikTok, and Facebook.    

    About GoldieBlox 

    GoldieBlox is a multimedia company on a mission to make Science, Technology, Engineering and Math (STEM) fun and accessible for all youth, especially girls, who have been underrepresented in STEM fields. Founded by Stanford engineer Debbie Sterling, GoldieBlox is known for “disrupting the pink aisle” and challenging gender stereotypes with the world’s first girl engineer and coder characters in children’s toys. For the past decade, GoldieBlox has inspired millions of girls around the world with videos, animation, books, apps, curriculum, toys, and merchandise; the tools that empower girls to build their confidence, dreams and ultimately, their futures.   

    GoldieBlox has been recognized as a disruptive leader in educational entertainment and has reached billions of consumers through TV, radio and digital as the first startup company to win a free Super Bowl commercial and have a float in the Macy’s Thanksgiving Day Parade. GoldieBlox and its founder, Debbie Sterling, have won numerous awards, including the Toy Industry’s Educational Toy of the Year Award, Fast Company’s list of Most Innovative Companies, Fortune’s 40 Under 40, President Obama’s Ambassadorship for Global Entrepreneurship, and the National Women’s History Museum’s “Living Legacy” award for inspiring girls around the world.   

    About Discovery Education 

    Discovery Education is the worldwide edtech leader whose state-of-the-art digital platform supports learning wherever it takes place. Through its award-winning multimedia content, instructional supports, innovative classroom tools, and social impact programs, Discovery Education helps educators deliver equitable learning experiences engaging all students and supporting higher academic achievement on a global scale. Discovery Education serves approximately 4.5 million educators and 45 million students worldwide, and its resources are accessed in over 100 countries and territories. Inspired by the global media company Warner Bros. Discovery, Inc. Discovery Education partners with districts, states, and trusted organizations to empower teachers with leading edtech solutions that support the success of all learners. Explore the future of education at www.discoveryeducation.com

    eSchool News Staff
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    ESchool News Staff

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  • Chemists craft colorful organic molecules.

    Chemists craft colorful organic molecules.

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    Newswise — CAMBRIDGE, MA — Chains of fused carbon-containing rings have unique optoelectronic properties that make them useful as semiconductors. These chains, known as acenes, can also be tuned to emit different colors of light, which makes them good candidates for use in organic light-emitting diodes.

    The color of light emitted by an acene is determined by its length, but as the molecules become longer, they also become less stable, which has hindered their widespread use in light-emitting applications.

    MIT chemists have now come up with a way to make these molecules more stable, allowing them to synthesize acenes of varying lengths. Using their new approach, they were able to build molecules that emit red, orange, yellow, green, or blue light, which could make acenes easier to deploy in a variety of applications.

    “This class of molecules, despite their utility, have challenges in terms of their reactivity profile,” says Robert Gilliard, the Novartis Associate Professor of Chemistry at MIT and the senior author of the new study. “What we tried to address in this study first was the stability problem, and second, we wanted to make compounds where you could have a tunable range of light emission.”

    MIT research scientist Chun-Lin Deng is the lead author of the paper, which appears today in Nature Chemistry.

    Colorful molecules

    Acenes consist of benzene molecules — rings made of carbon and hydrogen — fused together in a linear fashion. Because they are rich in sharable electrons and can efficiently transport an electric charge, they have been used as semiconductors and field-effect transistors (transistors that use an electric field to control the flow of current in a semiconductor).

    Recent work has shown that acenes in which some of the carbon atoms are replaced, or “doped,” with boron and nitrogen have even more useful electronic properties. However, like traditional acenes, these molecules are unstable when exposed to air or light. Often, acenes have to be synthesized within a sealed container called a glovebox to protect them from air exposure, which can lead them to break down. The longer the acenes are, the more susceptible they are to unwanted reactions initiated by oxygen, water, or light.

    To try to make acenes more stable, Gilliard decided to use a ligand that his lab has previously worked with, known as carbodicarbenes. In a study published last year, they used this ligand to stabilize borafluorenium ions, organic compounds that can emit different colors of light in response to temperature changes.

    For this study, Gilliard and his co-authors developed a new synthesis that allowed them to add carbodicarbenes to acenes that are also doped with boron and nitrogen. With the addition of the new ligand, the acenes became positively charged, which improved their stability and also gave them unique electronic properties.

    Using this approach, the researchers created acenes that produce different colors, depending on their length and the types of chemical groups attached to the carbodicarbene. Until now, most of the boron, nitrogen-doped acenes that had been synthesized could emit only blue light.

    “Red emission is very important for wide-ranging applications, including biological applications like imaging,” Gilliard says. “A lot of human tissue emits blue light, so it’s difficult to use blue-fluorescent probes for imaging, which is one of the many reasons why people are looking for red emitters.”

     

    Better stability

    Another important feature of these acenes is that they remain stable in both air and water. Boron-containing charged molecules with a low coordination number (meaning the central boron atom has few neighbors) are often highly unstable in water, so the acenes’ stability in water is notable and could make it feasible to use them for imaging and other medical applications.

    “One of the reasons why we’re excited about the class of compounds that we’re reporting in this paper is that they can be suspended in water. That opens up a wide range of possibilities,” Gilliard says.

    The researchers now plan to try incorporating different types of carbodicarbenes to see if they can create additional acenes with even better stability and quantum efficiency (a measure of how much light is emitted from the material).

    “We think it will be possible to make a lot of different derivatives that we haven’t even synthesized yet,” Gilliard says. “There are a lot of optoelectronic properties that can be dialed in that we have yet to explore, and we’re excited about that as well.”

    Gilliard also plans to work with Marc Baldo, an MIT professor of electrical engineering, to try incorporating the new acenes into a type of solar cell known as a single-fission-based solar cell. This type of solar cell can produce two electrons from one photon, making the cell much more efficient.

    These types of compounds could also be developed for use as light-emitting diodes for television and computer screens, Gilliard says. Organic light-emitting diodes are lighter and more flexible than traditional LEDs, produce brighter images, and consume less power.

    “We’re still in the very early stages of developing the specific applications, whether it’s organic semiconductors, light-emitting devices, or singlet-fission-based solar cells, but due to their stability, the device fabrication should be much smoother than typical for these kinds of compounds,” Gilliard says.

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    The research was funded by the Arnold and Mabel Beckman Foundation and the National Science Foundation Major Research Instrumentation Program.

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    Massachusetts Institute of Technology (MIT)

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  • Scientists warn of conflicts ahead of UN talks on plastic and chemicals

    Scientists warn of conflicts ahead of UN talks on plastic and chemicals

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    Newswise — An international group of 35 scientists is calling out conflicts of interest plaguing global plastic treaty negotiations and that have interfered with timely action on other health and environmental issues. They urge the implementation of strict guidelines to prevent the same problems from affecting the UN’s upcoming Science Policy Panel on chemicals. Their concerns and recommendations are outlined in a featured paper in the journal Environmental Science & Technology.

    “From Big Tobacco to Big Oil, powerful industries use the same playbook to manufacture doubt and sow misinformation,” said co-author Bethanie Carney Almroth, a Professor at the Department of Biological and Environmental Sciences, University of Gothenburg. “The plastic and chemical industries already have a long history of deploying these tactics to hamper regulatory efforts. Our health and that of the planet upon which we rely, can’t afford any further subversion of efforts to reduce the widespread contamination of our air and water.”

    The group’s warning comes as countries prepare to meet next week for the third UN plastic treaty negotiation session in Nairobi. Though scientists had advised against it, the plastic and petrochemical industries were actively involved in the first round of negotiations in 2022. The paper notes that industry representatives pushed misleading statements, including the debunked claim that plastic production will help fight climate change. To date, no action has been taken to curb these conflicts of interest.  

    The scientists express concern that similar issues could arise in the development of the UN Science Policy Panel on chemicals, waste, and pollution. The UN Environment Assembly decided in 2022 to establish this Panel to support countries in their efforts to protect human and ecosystem health through scientific assessments. As the working group to create the Panel will meet Dec. 11-15, today’s paper is a call to protect its work from undue influence by companies with a vested interest in revenue-generating chemicals.    

    “Letting polluters have a say in pollution protections is the epitome of the fox guarding the henhouse,” said lead author Andreas Schäffer, a Professor at the Institute for Environmental Research, RWTH Aachen University. “Just like the tobacco industry was restricted from WHO’s work on smoking, the UN shouldn’t let the chemical industry’s hired guns dilute global guidelines for chemical and waste management.”

    The participation of industry in a UN intergovernmental science-policy body would not be unprecedented. For example, fossil fuel representatives co-authored major reports of the Intergovernmental Panel on Climate Change, the Science Policy’s Panel analogue for climate. 

    To ensure the effectiveness of the Science Policy Panel, the scientists who co-authored the paper issue the following key recommendations that should be incorporated into the process:

    • Define clear and strict conflict of interest provisions.
    • Do not confuse the undesirable conflicts of financial or political competing interests with legitimate interests or biases.
    • Install regular audits of the Panel’s work to check for conflict of interest.
    • Secure as many elements of transparency as possible.

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    Green Science Policy Institute

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  • Plastics treaty: Cut pollution at source

    Plastics treaty: Cut pollution at source

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    Newswise — The new Global Plastics Treaty must tackle the problem at source, researchers say.

    An international negotiation meeting (INC-3) in Kenya begins on Monday, aiming to further develop a legally binding treaty on plastic pollution.

    Writing in the journal Science, researchers say the treaty must prioritise “upstream” issues: cutting total production and consumption of plastics, phasing out hazardous chemicals and tackling fossil fuel subsidies.

    They highlight a “worrying” level of focus on downstream recycling and waste management – when the true solution must address the full life cycle of plastics.

    They say the treaty must be holistic – with more focus on early interventions and the people, places and ecosystems most impacted by plastic pollution.

    “Right now, simply too much attention and capital is focussed ‘downstream’ – recycling and cleaning up plastic already in the environment, in many cases just after a single use ” said Dr Mengjiao (Melissa) Wang, from Greenpeace Research Laboratories at the University of Exeter.

    “That is vital work, but it can only be part of the solution, and only if done in a safe, environmentally sound and socially just way.

    “Removing the mess while making more is a doomed strategy. We cannot recycle our way out.

    “An effective treaty must be holistic, covering everything from fossil fuel extraction and plastic production to recycling and removing waste that already pollutes our land and ocean.”

    Currently, “downstream” recovery and recycling receives 88% of investment money – while just 4% is directed to “upstream” reuse solutions.

    The authors say this imbalance comes from “fossil-fuel-entwined political economy of plastics”, which continues to accelerate production, consumption and waste, adding further to the triple Planetary Crisis – climate change, biodiversity loss and pollution.

    They say the zero draft of the treaty “disproportionately emphasises waste management investment and neglects opportunities” for more efficient and cost-effective upstream strategies like reduction, redesign and reuse.

    The researchers say the treaty should require polymer manufacturers to pay a “substantial fee pegged to the quantity of primary plastics produced”, define criteria for strong and independent Extended Producer Responsibility schemes, and ensure both public and private financing align with the zero waste hierarchy by prioritising upstream strategies. 

    An effective Plastics Treaty to close the back door for fossil fuels

    The new treaty could and should become a global mechanism, to close a key loophole left by the Paris Agreement.

    “The problem of plastic pollution is huge, and it can feel overwhelming,” said Dr Lucy Woodall, from the University of Exeter.

    “But there are opportunities and challenges at each stage of the life cycle of plastics – from fossil fuel extraction onwards.”

    Global climate governance aims to stop the burning of fossil fuels, but they  could still be extracted and used to make plastics – so the Plastics Treaty provides a not-to-be-missed opportunity to close this “back door”.

    In three letters to Science, the researchers – the majority from the Scientists’ Coalition for an Effective Plastics Treaty – highlight several other points that the treaty must include.

    “One vital step is to focus on ecosystems,” said Dr Woodall.

    “Once in the environment, plastic litter can entangle and choke wildlife, and plastic objects can act as a reservoir for invasive species and concentrate other pollutants.

    “Plastics can also break down into potentially toxic micro- and nanoplastics.”

    The treaty’s zero draft used terms such as “hotspot” and “cleanup” – putting the focus on concentrations rather than the natural systems and their specific context, therefore the well-being and livelihoods of the nature and people these pollutants affect are ignored.

    “This implies that the plastics problem can be solved without considering ecosystem restoration and the disproportionate burden of plastic pollution in some ecosystems,” Dr Woodall said.

    “Vibrant ecosystems are vital for biodiversity and human health, so protecting them should be the centre of our approach.”

    ‘Chemical simplification’

    Chemicals in plastics are one of the key barriers to addressing global plastic pollution.

    Current regulations don’t require producers to track or publish information on the levels of harmful chemicals.

    The authors argue for “chemical simplification”, significantly reducing the production and use of especially hazardous chemicals, and increasing transparency and traceability along the whole supply chain, to fulfil one of the many necessary steps to ensure products can be safely and effectively recycled.

    The researchers are hopeful that an effective treaty can be agreed – but some countries are expected to resist more ambitious language and delay the process.

    “When we speak to negotiators, they give us a political ‘reality check’ about balancing ambition with getting a treaty agreed in due time,” Dr Wang said.

    “In return, our role as scientists is to provide a scientific reality check about the scale of this problem and the solutions that can actually work to bring us back to the safe operating space of the earth.

    “We need a treaty that is holistic and ambitious, tackling every stage of this problem – extraction, production, resource allocation – to stop the build-up of plastic waste and harmful chemicals in our planet’s precious ecosystems.”

    The letters published in Science are entitled: “Chemical simplification and tracking in plastics”, “Plastics treaty text must center ecosystems” and “Finance plastics reuse, redesign, and reduction”.


     

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  • Rubber behavior: Dynamics decoded

    Rubber behavior: Dynamics decoded

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    New device could improve the outcomes of cell-based therapies

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    Northwestern University

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  • Rubber behavior: Dynamics decoded

    Rubber behavior: Dynamics decoded

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    Newswise — Rubber-like materials, commonly used in dampeners, possess a unique property known as dynamic viscoelasticity, enabling them to convert mechanical energy from vibrations into heat while exhibiting spring-like and flow-like behaviors simultaneously. Customization of these materials is possible by blending them with compounds of specific molecular structures, depending on the dynamic viscosity requirements.

    However, the underlying mechanisms behind the distinct mechanical properties of these materials remain unclear. A primary reason for this knowledge gap has been the absence of a comprehensive system capable of simultaneously measuring the mechanical properties and observing the microstructural dynamics of these materials. While X-ray computed tomography (CT) has recently emerged as a promising option for a non-destructive inspection of the internal structure of materials down to nano-scale resolutions, it is not suited for observation under dynamic conditions.

    Against this backdrop, a team of researchers, led by Associate Professor (tenure-track) Masami Matsubara from the School of Creative Science and Engineering at the Faculty of Engineering at Waseda University in Japan, has now developed an innovative system that can conduct dynamic mechanical analysis and dynamic micro X-ray CT imaging simultaneously. Their study was made available online on October 19, 2023 and will be published in Volume 205 of the journal Mechanical Systems and Signal Processing on December 15, 2023.

    By integrating X-ray CT imaging performed at the large synchrotron radiation facility Spring-8(BL20XU) and mechanical analysis under dynamic conditions, we can elucidate the relationship between a material’s internal structure, its dynamic behavior, and its damping properties,” explains Dr. Matsubara. At the core of this novel system is the dynamic micro X-ray CT and a specially designed compact shaker developed by the team that is capable of precise adjustment of vibration amplitude and frequency.

    The team utilized this innovative system to investigate the distinctions between styrene-butadiene rubber (SBR) and natural rubber (NR), as well as to explore how the shape and size of ZnO particles influence the dynamic behavior of SBR composites.

    The researchers conducted dynamic micro X-ray CT scans on these materials, rotating them during imaging while simultaneously subjecting them to vibrations from the shaker. They then developed histograms of local strain amplitudes by utilizing the local strains extracted from the 3D reconstructed images of the materials’ internal structures. These histograms, in conjunction with the materials’ loss factor, a measure of the inherent damping of a material, were analyzed to understand their dynamic behavior.

    When comparing materials SBR and NR, which have significantly different loss factors, the team found no discernible differences between their local strain amplitude histograms. However, the histograms displayed wider strain distributions in the presence of composite particles like ZnO. This suggests that strain within these materials is non-uniform and depends on the shape and size of the particles, which may have masked any changes from the addition of the particles.

    This technology can allow us to study the microstructure of rubber and rubber-like materials under dynamic conditions and can result in the development of fuel-efficient rubber tires or gloves that do not deteriorate. Moreover, this technology can also enable the dynamic X-ray CT imaging of living organs that repeatedly deform, such as the heart, and can even pave the way for the development of artificial organs,” says Dr. Matsubara, highlighting the importance of this study.

    Overall, this breakthrough technology has the potential to advance the understanding of the microstructure of viscoelastic materials, likely opening the doors for the development of novel materials with improved properties.

     

    ***

     

    Reference

    DOI: https://doi.org/10.1016/j.ymssp.2023.110875

    Authors: Masami Matsubara1, Ryo Takara2, Taichi Komatsu2, Shogo Furuta2, Khoo Pei Loon2, Masakazu Kobayashi2, Hitomu Mushiaki3, Kentaro Uesugi4, Shozo Kawamura2, and Daiki Tajiri2

    Affiliations      

    1Department of Modern Mechanical Engineering, Waseda University

    2Department of Mechanical Engineering, Toyohashi University of Technology

    3Hyogo Prefectural Institute of Technology

    4Japan Synchrotron Radiation Research Institute

     

     

    About Waseda University

    Located in the heart of Tokyo, Waseda University is a leading private research university that has long been dedicated to academic excellence, innovative research, and civic engagement at both the local and global levels since 1882. The University has produced many changemakers in its history, including nine prime ministers and many leaders in business, science and technology, literature, sports, and film. Waseda has strong collaborations with overseas research institutions and is committed to advancing cutting-edge research and developing leaders who can contribute to the resolution of complex, global social issues. The University has set a target of achieving a zero-carbon campus by 2032, in line with the Sustainable Development Goals (SDGs) adopted by the United Nations in 2015. 

    To learn more about Waseda University, visit https://www.waseda.jp/top/en

     

    About Associate Professor Masami Matsubara

    Masami Matsubara is an Associate Professor (tenure-track) at the School of Creative Science and Engineering of the Faculty of Science and Engineering at Waseda University, Japan. He earned his Ph.D. from Doshisha University. His research focuses on the mechanics of materials, mechatronics, and dynamic modelling. He has recently worked on vibration reduction methods and dynamic design for large-scale numerical analysis models and detailed design and experimental methods for component and unit testing. He is a member of the Japan Society of Mechanical Engineers (JSME) and SAE International. He received the JSME Medal for Outstanding Paper in 2014, 2020, and 2022.


     

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  • Scientists reveal structures of neurotransmitter transporter

    Scientists reveal structures of neurotransmitter transporter

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    Newswise — (Memphis, Tenn – November 1, 2023) Neurons talk to each other using chemical signals called neurotransmitters. Scientists at St. Jude Children’s Research Hospital have drawn on structural biology expertise to determine structures of vesicular monoamine transporter 2 (VMAT2), a key component of neuronal communication. By visualizing VMAT2 in different states, scientists now better understand how it functions and how the different shapes the protein takes influence drug binding — critical information for drug development to treat hyperkinetic (excess movement) disorders such as Tourette syndrome. The work was published today in Nature.    

    How our neurons talk to each other 

    Chemical compounds called monoamines, which include dopamine, serotonin and adrenaline, play a central role in neuronal communication. These molecules affect how the brain works, controlling our emotions, sleep, movement, breathing, circulation and many other functions. Monoamines are neurotransmitters (signaling molecules) produced and released by neurons, but before they can be released, they must first be packaged into vesicles.  

    Vesicles are cellular compartments that store neurotransmitters before they are released at the synapses (the junction through which chemical signals pass from one neuron to another). Think of vesicles as the cargo ships of the neuronal cell — neurochemicals are packed inside them and taken to where they need to go. VMATs are proteins on the membrane of these vesicles that move monoamines into the space within, acting like loading cranes for the cargo ships.  

    “VMATs are transporters that are required for packing these monoamine neurotransmitters into synaptic vesicles,” explained co-corresponding author Chia-Hsueh Lee, Ph.D., St. Jude Department of Structural Biology.   

    Once the VMAT has packed the vesicle with monoamines, the “cargo ship” moves towards the synaptic gap (the space between neurons), where it releases the chemical compounds.  

    The many faces of monoamine transporters 

    There are two types of VMAT: VMAT1 and VMAT2. VMAT1 is more specialized, found only in neuroendocrine cells, whereas VMAT2 is found throughout the neuronal system and has significant clinical relevance.   

    “We knew that VMAT2 is physiologically very important,” Lee said. “This transporter is a target for pharmacologically relevant drugs used in the treatment of hyperkinetic disorders such as chorea and Tourette Syndrome.” 

    Despite their importance, the structure of VMAT2, which would allow researchers to investigate how it works fully, had remained elusive. Lee and his team used cryo-electron microscopy (cryo-EM) to obtain structures of VMAT2 bound to the monoamine serotonin and the drugs tetrabenazine and reserpine, which are used to treat chorea and hypertension, respectively. This was no easy feat.  

    “VMAT2 is a small membrane protein,” explained co-first author Yaxin Dai, PhD., St. Jude Department of Structural Biology. “This makes it a very challenging target for cryo-EM structure determination.”  

    Despite the difficulty and using some clever tricks, the team captured multiple structures of VMAT2 that allowed them to tease out how the protein functions and investigate how exactly those drugs work. “VMAT transporters adopt multiple conformations [shapes] while transporting their substrate. This is called alternating access transport, where the protein is either “outward” or “inward” facing,” explained co-first author Shabareesh Pidathala, Ph.D., St. Jude Department of Structural Biology. “To completely gain mechanistic understanding at an atomic level, we needed to capture multiple conformations of this transporter.”  

    Answering a 40-year-old question 

    The researchers discovered this dynamic mechanism means multiple opportunities for drugs to bind. They confirmed that reserpine and tetrabenazine bind two different conformations of VMAT2. “30 or 40 years of pharmacological research had suggested that these two drugs bind to the transporter in different ways,” said Pidathala, “but nobody knew the atomic details of how this works. Our structures nicely demonstrate that these two drugs stabilize two different conformations of the transporter to block its activity.” 

    The structure of VMAT2 with serotonin bound allowed the researchers to pinpoint specific amino acids that interact with the neurotransmitter and drive transport. “We believe this is a common mechanism that this transporter uses to engage all the monoamines,” said Lee.  

    While this work offers a huge leap forward in understanding monoamine transport, Lee and his team are delving deeper into its mechanism. For example, the intake of monoamines into vesicles is fueled by protons moving in the other direction. “We identified amino acids that are important for this proton-dependent process,” Lee said, “but we still don’t know how exactly protons drive this transport. Determining this mechanism is our future direction, which will help us to fully appreciate how this transporter works.”  

    Authors and funding 

    The study’s other first author is Shuyun Liao of the School of Life Sciences, Peking University. The study’s co-corresponding author is Zhe Zhang of the School of Life Sciences, Peking University. Other authors include Xiao Li and Chi-Lun Chang of St. Jude, and Changkun Long of the School of Life Sciences, Peking University.  

    The study was supported by grants from National Institutes of Health (R01GM143282), the National Key Research and Development Program of China (2021YFA1302300), the National Natural Science Foundation of China (32171201), the SLS-Qidong innovation fund, the Li Ge-Zhao Ning Life Science Youth Research Foundation, the State Key Laboratory of Membrane Biology of China, and ALSAC, the fundraising and awareness organization of St. Jude. 

     

    St. Jude Children’s Research Hospital 

    St. Jude Children’s Research Hospital is leading the way the world understands, treats and cures childhood cancer, sickle cell disease and other life-threatening disorders. It is the only National Cancer Institute-designated Comprehensive Cancer Center devoted solely to children. Treatments developed at St. Jude have helped push the overall childhood cancer survival rate from 20% to 80% since the hospital opened more than 60 years ago. St. Jude shares the breakthroughs it makes to help doctors and researchers at local hospitals and cancer centers around the world improve the quality of treatment and care for even more children. To learn more, visit stjude.org, read St. Jude Progress blog, and follow St. Jude on social media at @stjuderesearch.   

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  • How space junk is making the sky more metallic

    How space junk is making the sky more metallic

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    As several decades’ worth of satellites and spacecraft have fallen back to Earth, their flaming-hot atmospheric reentries have started polluting the stratosphere with metal.

    Data collected by a high-altitude research plane over the Arctic during a National Oceanic and Atmospheric Administration (NOAA) mission, revealed that 20 different metallic elements that do not naturally occur in Earth’s atmosphere were present. This including silver, iron, lead, magnesium, titanium, beryllium, chromium, nickel and zinc.

    As revealed in a paper published in the journal PNAS, the scientists state that this metal pollution in the stratosphere is likely due to the huge amount of space junk we have in orbit falling back into the atmosphere one by one.

    Stock image of the Earth from space. Scientists have found higher levels of metals in the stratosphere than expected.
    ISTOCK / GETTY IMAGES PLUS

    “About half of the particles in the stratosphere naturally contain small amounts of iron, magnesium, and other metals from meteors. Right now there is much more iron from meteors than metals from reentering satellites and rocket boosters. However, the metals from reentry are different from those in meteors, so reentry is introducing new metals into the stratosphere,” Daniel Murphy, a research chemist at the NOAA Chemical Sciences Laboratory, told Newsweek.

    The foreign metals were found embedded in around 10 percent of sulfuric acid particles that largely make up the stratosphere, which is the atmospheric layer between 7.5 and 31 miles above the ground. The scientists worry that with increased satellite launches in the coming years, the level of such metals in the atmosphere will increase as these satellites reenter, jumping to being embedded to as much as 50 percent of sulfuric acid particles.

    “With expected increases in the number of satellites, the amount of aluminum and other metals from reentry could become comparable to the amount of iron and other metals from meteors,” Murphy said.

    The potential for this increased metal level in the stratosphere to cause harm to humans is still unclear, the scientists say, but it is not likely to directly affect peoples’ health.

    “We are just becoming aware that the metals from spacecraft reentry end up in particles in the stratosphere so we don’t yet know the possible impacts on the stratosphere. We haven’t observed any definite impacts but but it is uncomfortable to not know whether or not there are impacts from this rapidly growing industry,” Murphy said.

    reentry
    NOAA graphic of how reentering satellites and space junk leach metal into the atmosphere.
    Chelsea Thompson/NOAA

    “We do not think there is much chance of direct health effects on humans compared to the much larger emissions from industrial processes at ground level. Any harm, if it occurs, would be indirect through changes in the stratosphere.”

    Over 15,000 satellites have been put into orbit around the Earth since the 1950s. There are 8,774 satellites currently in orbit around the Earth as of October 25, according to the tracking website Orbiting Now. There is also a huge amount of space junk and debris in orbit, with millions of minuscule chunks of metal zooming around the planet.

    Two of the most surprising elements the scientists saw in the aforementioned particles were niobium and hafnium, both of which are rare elements that are not expected in the stratosphere, but are used in heat-resistant, high-performance alloys.

    Do you have a tip on a science story that Newsweek should be covering? Do you have a question about satellites in orbit? Let us know via science@newsweek.com.