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  • Here’s how to still eat healthy at the airport and on a plane

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    Transportation Secretary Sean Duffy said he’d like airlines to start serving something other than pretzels and buttery cookies.

    “I would love some better snacks,” Duffy told the conservative news site Blaze Media on Tuesday. “I would love a little healthier snack on the airplane.”


    Most airlines no longer serve free meals, but they do still hand out snack food and juice, soda and coffee to passengers. American Airlines, the biggest airline operating out of Philadelphia International Airport, gives people a choice between small bags of pretzels and packages of Biscoff cookies — or both.

    Pretzels may be convenient, but they are generally low in nutrients, high in sodium and are made with refined carbs that leave people unsated and ready to snack again soon.

    Biscoff cookies are high in added sugars and saturated fat – although they do not contain trans fats and have lower calorie and saturated fat contents compared with Oreos and Chips Ahoy! cookies.

    Duffy made his complaint as a passing comment, not as part of an official policy change, according to the New York TimesBut his remarks spark the question: How can people eat healthier when flying?

    Here are some tips:

    Go nuts

    Many airlines no longer serve peanuts or peanut products due to allergies, but some carriers still offer other types of nuts. While salted varieties present sodium concerns for people with high blood pressure and other medical issues, nuts are high in protein. If available and allergies are not a concern, choose the nuts. 

    Drink up

    Due to low humidity levels in airline cabins, people are at risk of getting dehydrated during flights, so drinking lots of water before, during and after flying is key, according to the Cleveland Clinic. Hydrating well can also help mitigate jet lag and fatigue. The general rule of thumb is 8 ounces of water for every hour of flight, according to AARP.

    Stay away from alcoholic and caffeinated drinks because they can disrupt sleep, which may already be hard to come by on flights. Also, caffeine is a stimulant, so anxious travelers should avoid it, Condé Nast Traveler advises.

    Carbonated drinks may also cause burping and flatulence, unpleasant for the consumer and fellow travelers, AARP warns.

    BYO

    The best and least expensive bet for eating healthy in the airport and on the plane is to bring your own food.

    Registered dietitian Andy De Santis recently told the Healthy that he packs chicken sandwiches on whole-grain bread — a fiber-protein combo — when he flies.

    Other high-protein foods, such as greek yogurt, flaxseed crackers and seeds, are also handy and healthy.

    Health editor Ally Head recently shared her home-packed travel snack selections with Marie Claire: a Tupperware container full of carrot, celery and other vegetable sticks, olives, cheese cubes, a spinach side salad and whole-grain carbs, such as pumpernickel bread.

    Condé Nast Traveler offers these tips for how to pack food for the plane:

    • Airlines generally allow people to bring solid food, such as snacks, dried fruit and sandwiches, in their carry-on luggage.

    • Don’t bring ice packs or frozen food.

    • Avoid wrapping food in aluminum foil because it can set off security alarms.

    • Liquids of 3.4-ounces or less are allowed through security.

    • Otherwise, pack an empty water bottle to drink from while waiting at the gate and to fill before a flight.

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    Courtenay Harris Bond

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  • Headache and Migraine Relief from Foods  | NutritionFacts.org

    Headache and Migraine Relief from Foods  | NutritionFacts.org

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    Plant-based diets are put to the test for treating migraine headaches.

    Headaches are one of the top five reasons people end up in emergency rooms and one of the leading reasons people see their doctors in general. One way to try to prevent them is to identify their triggers and avoid them. Common triggers for migraines include stress, smoking, hunger, sleep issues, certain foods (like chocolate, cheese, and alcohol), your menstrual cycle, or certain weather patterns (like high humidity).

    In terms of dietary treatments, the so-called Father of Modern Medicine, William Osler suggested trying a “strict vegetable diet.” After all, the nerve inflammation associated with migraines “may be reduced by a vegan diet as many plant foods are high in anti-inflammatory compounds and antioxidants, and likewise, meat products have been reported to have inflammatory properties.” It wasn’t put to the test, though, for another 117 years.

    As I discuss in my video Friday Favorites: Foods That Help Headache and Migraine Relief, among study participants given a placebo supplement, half said they got better, while the other half said they didn’t. But, when put on a strictly plant-based diet, they did much better, experiencing a significant drop in the severity of their pain, as you can see in the graph below and at 1:08 in my video

    Now, “it is possible that the pain-reducing effects of the vegan diet may be, at least in part, due to weight reduction.” The study participants lost about nine more pounds when they were on the plant-based diet for a month, as shown below, and at 1:22. 

    Even just lowering the fat content of the diet may help. Those placed on a month of consuming less than 30 daily grams of fat (for instance, less than two tablespoons of oil all day), experienced “statistically significant decreases in headache frequency, intensity, duration, and medication intake”—a six-fold decrease in the frequency and intensity, as you can see below and at 1:44 in my video. They went from three migraine attacks every two weeks down to just one a month. And, by “low fat,” the researchers didn’t mean SnackWell’s; they meant more fruits, vegetables, and beans. Before the food industry co-opted and corrupted the term, eating “low fat” meant eating an apple, for example, not Kellogg’s Apple Jacks.  

    Now, they were on a low-fat diet—about 10 percent fat for someone eating 2,500 calories a day. What about just less than 20 percent fat compared to a more normal diet that’s still relatively lower fat than average? As you can see below and at 2:22 in my video, the researchers saw the same significant drops in headache frequency and severity, including a five-fold drop in attacks of severe pain. Since the intervention involved at least a halving of intake of saturated fat, which is mostly found in meat, dairy, and junk, the researchers concluded that reduced consumption of saturated fat may help control migraine attacks—but it isn’t necessarily something they’re getting less of. There are compounds “present in Live green real veggies” that might bind to a migraine-triggering peptide known as calcitonin gene-related peptide, CGRP. 

    Drug companies have been trying to come up with something that binds to CGRP, but the drugs have failed to be effective. They’re also toxic, which is a problem we don’t have with cabbage, as you can see below and at 3:01 in my video

    Green vegetables also have magnesium. Found throughout the food supply but most concentrated in green leafy vegetables, beans, nuts, seeds, and whole grains, magnesium is the central atom to chlorophyll, as shown below and at 3:15. So, you can see how much magnesium foods have in the produce aisle by the intensity of their green color. Although magnesium supplements do not appear to decrease migraine severity, they may reduce the number of attacks you get in the first place. You can ask your doctor about starting 600 mg of magnesium dicitrate every day, but note that magnesium supplements can cause adverse effects, such as diarrhea, so I recommend getting it the way nature intended—in the form of real food, not supplements.  

    Any foods that may be particularly helpful? You may recall that I’ve talked about ground ginger. What about caffeine? Indeed, combining caffeine with over-the-counter painkillers, like Tylenol, aspirin, or ibuprofen, may boost their efficacy, at doses of about 130 mg for tension-type headaches and 100 mg for migraines. That’s about what you might expect to get in three cups of tea, as you can see below, and at 4:00 in my video. (I believe it is just a coincidence that the principal investigator of this study was named Lipton.) 

    Please note that you can overdo it. If you take kids and teens with headaches who were drinking 1.5 liters of cola a day and cut the soda, you can cure 90 percent of them. However, this may be a cola effect rather than a caffeine effect. 

    And, finally, one plant food that may not be the best idea is the Carolina Reaper, the hottest chili pepper in the world. It’s so mind-numbingly hot it can clamp off the arteries in your brain, as seen below and at 4:41 in my video, and you can end up with a “thunderclap headache,” like the 34-year-old man who ate the world’s hottest pepper and ended up in the emergency room. Why am I not surprised it was a man? 

    I’ve previously covered ginger and topical lavender for migraines. Saffron may help relieve PMS symptoms, including headaches. A more exotic way a plant-based diet can prevent headaches is by helping to keep tapeworms out of your brain.

    Though hot peppers can indeed trigger headaches, they may also be used to treat them. Check out my video on relieving cluster headaches with hot sauce

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    Michael Greger M.D. FACLM

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  • Supermom In Training: Do you let your kids have caffeine? Some do…

    Supermom In Training: Do you let your kids have caffeine? Some do…

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    Do your kids drink coffee? Even though coffee is life for this mama, my kid doesn’t. But some do. I was listening to a radio show the other day and in some Latin American and Italian cultures, kids as young as toddlers are given coffee in the form of a latte. Some parents were appalled by this, and others said it’s been a custom in their household for generations.

    It might seem a bit surprising to give a child coffee, but do we not let them eat chocolate and drink soda or iced tea? These all contain caffeine.

    According to Johns Hopkins, too much caffeine in children can cause issues such as increased anxiety, increased heart rate and blood pressure, acid reflux, and sleep disturbance. They said that too much caffeine is dangerous for kids, and in very high doses, it can be toxic.

    The scariest part about coffee and kids is that we just don’t know… researchers don’t yet know the long-term effects of giving kids a morning cup of Joe. 

    Would you let your kids have coffee?

    A full-time work-from-home mom, Jennifer Cox (our “Supermom in Training”) loves dabbling in healthy cooking, craft projects, family outings, and more, sharing with Suburban readers everything she knows about being an (almost) superhero mommy.

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  • Should you sleep in socks? Experts say this hack might be the secret to falling asleep faster and waking up less

    Should you sleep in socks? Experts say this hack might be the secret to falling asleep faster and waking up less

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    If you’ve never been one to sleep in socks, you might want to give it a try.

    Sleeping in socks helps to regulate your body temperature, which can lead to falling asleep faster, waking up less, and sleeping in later, according to research.

    A study published in the Journal of Physiological Anthropology, found that men who wore socks fell asleep about seven minutes faster, slept 32 minutes longer, and woke up about seven times less often than those who didn’t wear socks.

    Though it may seem counterintuitive, sleeping in socks helps keep your core temperature—the temperature inside your body, not of your skin—low, wrote Michael Breus, PhD, clinical psychologist and sleep medicine expert, in a blog post on Sleep Doctor. Warming your skin by wearing socks lowers body temperature by expanding blood vessels near the skin, which allows the heat to escape. 

    When your core body temperature is regulated, it makes for better sleep, Breus said. 

    Temperature plays a role in quality sleep

    A drop in core body temperature signals to the body that it’s time to sleep and coincides with the release of melatonin—the sleep hormone. Experts suggest keeping your bedroom between 68 to 72 degrees Fahrenheit for ample sleep.

    “Some sources recommend an even colder room; however, I typically recommend temperatures at least two to five degrees cooler than a comfortable temperature in the house during the day,” Dr. Nilong Vyas, founder and owner of Sleepless in NOLA, a sleep consulting service, and medical review expert at Sleep Foundation, previously told Fortune.

    Wearing socks and sleeping in a cool room could be the perfect pairing for a high quality night of rest.

    What kind of socks should you sleep in?

    If you wear socks to sleep, ensure they aren’t so tight that they restrict blood flow, wrote Breus. It’s important the socks are comfortable so they don’t become a sleep distraction. Breus also suggested they be made of breathable fabrics like cotton, linen, or bamboo. And you should opt for a fresh, clean pair, not the ones you wore all day, behavioral sleep disorders specialist Michelle Drerup, PsyD, told the Cleveland Clinic.

    If you feel a sensory overload sleeping in socks, research suggests that putting your feet in a warm water bath before bed can give a similar effect. 

    Will sleeping in socks cure my restless nights?

    While sleeping in socks is worth a try to get better rest, it’s not a cure all. Socks aren’t a treatment for insomnia or other sleep conditions—you should talk to a medical professional for ongoing issues. And people with circulation issues should not sleep with socks without talking to their doctor first.
    But, along with unplugging before bed, dimming the lights, and avoiding caffeine too late in the day, putting on a pair of socks before bed might be a way to step up your sleep routine, and wake up better rested.

    For more on building healthy sleep habits:

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    Jordyn Bradley

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  • Should You Stir CBD Into Your Morning Coffee

    Should You Stir CBD Into Your Morning Coffee

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    Every morning, roughly 63% of Americans and 71% of Canadians savor a hot cup of coffee. It is a morning ritual shown in movies, memories and memes. But can it be a vehicle to help improve your mood and general state of mine.  CBD oil, which has gained popularity as a stress reliever over the last few years. Studies also show CBD reduces aggressive behavior and effectively helps you chill out. If it is all true, should stir CBD in into your morning coffee?

    Studies have shown CBD contains anti-anxiety, analgesic, and anti-inflammatory properties. Add the caffeine boost you receive from coffee and it seems like the perfect way to start your day. It’s widely reported by those who use both caffeine and CBD oil the combination can remove the jittery edge.

    However, combining CBD with your coffee fundamentally changes how it affects your body. That’s why experts recommend not doing so if you’re using the extract for medicinal purposes.

    RELATED: 5 Morning Activities To Help You Feel Happier

    “Those who want to use CBD for serious medical conditions, such as seizure disorders or inflammation from autoimmune disorders, should not take CBD in this manner, as accurate CBD dosing is extremely important for efficacy in these types of illnesses,” Bonni Goldstein, a California-based physician specializing in cannabinoid therapy.

    Photo by Nathan Dumlao via Unsplash

    A study backed up Goldstein. According to researchers analyzing cannabis tea, temperature changes CBD content in both hot and cold liquids. So, if you require precise dosing of medicine, it’s best not to dump your CBD oil into a hot cup of joe.

    RELATED: How Many People Can You Date At One Time

    Those approaching the issue from a wellness perspective don’t have such concerns. Anecdotal evidence of the therapeutic effects combining CBD and coffee to boost your day-to-day proceedings is mixed. Some say that CBD-infused coffee diminishes the buzzing rush caffeine delivers while lowering anxiety symptoms. But others find the pairing disorienting. Since CBD is also used to achieve a good night’s sleep, the cannabinoid’s drowsy properties fight with coffee’s caffeine to leave you groggy and unsatisfied.

    Most importantly, you should understand that CBD affects each individual differently. What works for you might not work for someone else. But we know for certain that dumping CBD oil into your coffee dramatically decreases its bioavailability, or the extent and rate at which the drug enters your body’s circulation to produce the desired effects. CBD oil taken sublingually, or underneath your tongue, maintains a bioavailability between 20-30%, but received orally, like in a drink, drops the bioavailability down to 6%. This is another reason medical experts don’t recommend patients combining the two.

    RELATED: CBD Coffee Is The Easy Way To Pain-Free Mornings

    If you’re committed to starting your day with CBD-infused coffee, but don’t want to sacrifice efficacy, we have a recommendation. A 2016 study reported that combining cannabinoids into a fatty acid allows CBD to bypass your metabolism — which is responsible for diminishing the plant’s impact — and increases bioavailability. This explains why many report the most therapeutic effects are found by adding organic butter or coconut oil to make a CBD coffee concoction. It’s a little more work, but your body will thank you for it later.

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    Sarah Johns

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  • Are Branched-Chain Amino Acids Good for Us?  | NutritionFacts.org

    Are Branched-Chain Amino Acids Good for Us?  | NutritionFacts.org

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    I discuss why we may not want to exceed the recommended intake of protein.

    Diabetes isn’t just about the amount of body fat, but also the distribution of body fat. At 0:26 in my video Are BCAA (Branched-Chain Amino Acids) Healthy?, you can view cross-sections of thighs from two different patients using MRI. In the images, the fat shows up as white and the thigh muscle is black. At first glance, you might think the bottom cross-section has more fat since it’s ringed with more white. That is the subcutaneous fat, the fat under the skin. But, if you look at the top cross-section, you’ll see how the middle of the thigh muscle is more marbled with fat, like those really fatty Japanese beef steaks. That is the fat infiltrating into the muscle. In the graph below and at 0:48 in my video, the two cross sections are colored so you can see the different types of fat: the fat infiltrating the muscle in red, the fat between the muscles in green, and subcutaneous fat outside of the muscles and under the skin in yellow. If you add up all three types of fat, both of those thighs actually have the same amount of fat—just distributed differently.

    This seems to be the critical factor in terms of determining insulin resistance, the cause of type 2 diabetes. Researchers found that the subcutaneous adipose tissue, the fat right under the skin, was not associated with insulin resistance. Going back to the two cross sections, as seen below and at 1:20 in my video, it is healthier to have the bottom thigh with the thicker ring of subcutaneous fat but less fat infiltrating muscle than the top thigh with more fat present in the muscle.

    Is it possible a more plant-based diet also affects a more healthful distribution of fat?

    We now know the effect of a vegetarian diet versus a conventional diabetic diet on thigh fat distribution in patients with type 2 diabetes. Researchers took 74 people with diabetes and randomly assigned them to follow either a vegetarian diet or a conventional diabetic diet. Both diets were calorie-restricted by the same number of calories. The vegetarian diet was also egg-free, and dairy was limited to a maximum of one serving of low-fat yogurt a day. What did the researchers find? The reduction in the more benign subcutaneous fat was comparable; it was about the same in both groups. However, the more dangerous fat—the fat lodged inside the muscle itself—“was reduced only in response to a vegetarian diet.” So, even getting the same number of calories, there can be a healthier weight loss on a more plant-based diet.

    Those eating strictly plant-based also had lower levels of fat stuck inside the individual muscle fibers themselves, which may help explain why vegans in particular are often found to have the lowest odds of diabetes. It is not just because vegans are generally slimmer either. Even if you match subjects pound for pound, there is significantly less fat inside the muscle cells of vegans compared to omnivores. This is a good thing, since storing fat in muscle cells “may be one of the primary causes of insulin resistance,” which is what’s behind both prediabetes and type 2 diabetes. On the other hand, if you put someone on a high-fat diet, the fat in their muscle cells shoots up by 54 percent in just a single week.

    What about a high-protein diet? That may undermine one of the principal benefits of weight loss: eliminating the weight-loss-induced improvement in insulin resistance. Researchers put obese individuals on a calorie-restricted diet of less than 1,400 calories a day until they lost 10 percent of their body weight. Half of the participants were getting more of a regular protein intake (73 grams a day), and the other half were on a higher-protein diet (about 105 daily grams). Normally, if you lose 10 percent of your body weight, your insulin resistance improves. That’s why it is so critical for obese individuals with type 2 diabetes to lose weight. However, the beneficial effect of a 10 percent weight loss was eliminated by the high protein intake. Those extra 32 grams of protein a day abolished the weight-loss benefit. “The failure to improve…insulin sensitivity in the WL-HP [weight-loss high-protein] group is clinically important because it reflects a failure to improve a major pathophysiological [cause-and-effect] mechanism involved in the development of T2D,” type 2 diabetes. In summary, the researchers concluded that they demonstrated “the protein content of a weight loss diet can have profound effects on metabolic function.” 

    Is this true of any protein? As you can see below and at 4:19 in my video, if you split it between animal protein versus plant protein, following people over time, intake of animal protein is associated with an increased risk of diabetes in most studies.

    Intake of plant protein, however, appears to have either a neutral or even protective association with diabetes, as shown below and at 4:25 in my video

    Those were just observational studies, though. People who eat a lot of animal protein might have many unhealthy behaviors. However, you see the same thing in randomized, controlled, interventional trials, where you can improve blood sugar control just by replacing sources of animal protein with plant protein.

    We think it may be the branched-chain amino acids concentrated in animal protein. Higher levels in the bloodstream are associated with obesity and the development of insulin resistance. As you can see below and at 5:00 in my video, we may be able to drop our levels by sticking to plant proteins, but you don’t know if that has metabolic effects until you put it to the test. 

    Ruining the suspense, researchers titled their study: “Decreased Consumption of Branched-Chain Amino Acids Improves Metabolic Health.” They demonstrated that “a moderate reduction in total dietary protein or selected amino acids can rapidly improve metabolic health,” and this included improving blood sugar control, while also decreasing body mass index (BMI) and body fat. As you can see at 5:27 in my video, the protein-restricted group was eating hundreds more calories per day, significantly more calories than the control group, so they should have gained weight. But, no. They lost weight! After about a month and a half, they were eating more calories but lost more weight—about five more pounds than participants in the control group who were eating fewer calories, as you can see at 5:38 in my video. What’s more, this “protein restriction” had people eat the recommended amount of protein per day, about 56 daily grams. They should have been called the normal protein group or the recommended protein group instead, and the group eating more typically American protein levels and suffering because of it should have been called the excess protein group. Just sticking to the recommended protein intake doubled the levels of a pro-longevity hormone called FGF21, too, but we’ll save that for another discussion.

    To better understand the negative impact of omnivores getting too much protein relative to vegetarians, see my video Flashback Friday: Do Vegetarians Get Enough Protein?.

    I have several additional videos and blogs that may help explain some of the benefits of plant-based proteins. Check in the related posts below.

    Of course, the best way to treat type 2 diabetes is to get rid of it by treating the underlying cause, as described in my video How Not to Die from Diabetes

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    Michael Greger M.D. FACLM

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  • How Safe Is Alternate-Day Intermittent Fasting?  | NutritionFacts.org

    How Safe Is Alternate-Day Intermittent Fasting?  | NutritionFacts.org

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    Eating every other day can raise your cholesterol. 
     
    Are there any downsides to fasting every other day? For example, might go all day without eating impair your ability to think clearly? Surprisingly, as I discuss in my video Is Alternate-Day Intermittent Fasting Safe?, the results appear to be “equivocal.” Some studies show no measurable effects and the ones that do fail to agree on which cognitive domains are affected. Might the cycles of fasting and feasting cause eating disorder–type behaviors, like bingeing? So far, no harmful psychological effects have been found. In fact, there may be some benefit. However, the studies that have put it to the test specifically excluded those with a documented history of eating disorders, for whom the effects may differ. 
     
    What about bone health? No change in bone mineral density was noted after six months of alternate-day fasting despite about 16 pounds of weight loss, which would typically result in a dip in bone mass. However, the researchers did not note any skeletal changes in the control group either, and they lost a similar amount of weight using continuous caloric restriction. They suggested this is because both groups tended to be “more physically active than the average obese American,” getting about 1,000 to 2,000 more steps a day. 
     
    Proponents of intermittent fasting suggest it can better protect lean body mass, but most of the intermittent trials have employed less accurate methods of body composition analysis, whereas the majority of continuous caloric restriction trials used “vastly more accurate techniques.” So, to date, it is not clear if there’s a difference in lean mass preservation. 
     
    Improvements in blood pressure and triglycerides have been noted on intermittent fasting regimens, though this is presumed to be due to the reduction in body fat since the effect appears to be “dependent on the amount of weight lost.” Alternate-day fasting can improve artery function, too, as you can see in the graph below and at 1:55 in my video, though it does depend on what you’re eating on the non-fasting day. For study participants randomized to an alternate-day diet high in saturated fat, their artery function worsened despite a ten-pound weight loss, whereas it improved, as expected, in the lower-fat group. The decline in artery function was presumed to be because of the pro-inflammatory nature of saturated fat. 

    A concern has been raised about the effects of alternate-day fasting on cholesterol. After 24 hours without food, LDL cholesterol may temporarily bump up, but this is presumably because so much fat is being released into the system by the fast. As you can see in the graph below and at 2:33 in my video, an immediate negative effect on carbohydrate tolerance may stem from the same phenomenon—the repeated elevations of free fat floating around in the bloodstream. After a few weeks, though, LDL levels start to drop as the weight comes off. However, results from the largest and longest trial of alternate-day fasting have given me pause. 


    A hundred obese men and women were randomized into one of three groups: alternate-day modified fasting (25 percent of their baseline calories on fasting days and 125 percent calories on eating days), continuous, daily caloric restriction (75 percent of baseline), or a control group instructed to maintain their regular diet. So, for those going into the trial eating 2,000 calories a day, they would continue to eat 2,000 calories a day in the control group. The calorie-restriction group would get 1,500 calories every day, and the intermittent-restriction group would alternate between 500 calories a day and 2,500 calories the next. 
     
    As you can see in the graph below and at 3:32 in my video, with the same overall, average, prescribed calorie cutting in the two weight-loss groups, they both lost about the same amount of weight, but, surprisingly, the cholesterol effects were different. In the continuous calorie-restriction group, the LDL levels dropped as expected compared to the control group as the pounds came off. 

    But, in the alternate-day modified fasting group, they didn’t, as you can see below, and at 3:55 in my video. At the end of the year, the LDL cholesterol in the intermittent fasting group ended up being 10 percent higher than in the constant calorie-restriction group—despite the same loss of body fat. Given that LDL cholesterol is a prime causal risk factor for heart disease, our number one killer—or is even the prime risk factor—this strikes a significant blow against alternate-day fasting. If you want to try it anyway, I would advise you to have your cholesterol monitored to make sure it comes down with your weight. 


    If you’re diabetic, you must talk with your physician about medication adjustment for any changes in diet, including fasting of any duration. Even with proactive medication reduction, advice to immediately break the fast should sugars drop too low, and weekly medical supervision, people with type 2 diabetes who fasted for even just two days a week were twice as likely to suffer from hypoglycemic episodes compared to an unfasted control group. We still don’t know the best way to tweak blood sugar medications to prevent blood sugar from dropping too low on fasting days. 
     
    Even fasting for just one day can significantly slow the clearance of some drugs (like the blood-thinning drug Coumadin) or increase the clearance of others (like caffeine). Fasting for 36 hours can cut your caffeine buzz by 20 percent. So, consultation with your medical professional before fasting is an especially good idea for anyone on any kind of medication. 

    If you missed it, check out Alternate-Day Intermittent Fasting Put to the Test
     
    So, with ambiguous cognitive, lean mass, and bone effects, plus these cholesterol findings, I wouldn’t suggest alternate-day fasting for weight loss, but dropping pounds isn’t the only thing this way of eating is purported to do. Check out Does Intermittent Fasting Increase Human Life Expectancy?
     
    For other types of intermittent fasting, total fasting, and more on fasting, check out the related videos below. 



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    Michael Greger M.D. FACLM

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  • Cannabeginners: What are Cannabis Alkaloids? | High Times

    Cannabeginners: What are Cannabis Alkaloids? | High Times

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    What does cannabis, coca leaf, and all coffee have in common? They all contain alkaloids, a powerful group of medicinal compounds found in plants around the world. While little is presently known about cannabis alkaloids, they are suspected to possess impressive medical benefits like other plant alkaloids. 

    Alkaloids vs. Cannabinoids

    Alkaloids are “one of the most common groups of chemicals that [have] medicinal properties found in plants,” commonly used alkaloids include “morphine, cocaine, nicotine, caffeine, quinine, ephedrine, and many more.” They derive their name, alkaloid, from the word alkali, chemicals that react like bases, counteracting acids. Usually found in the outer tissues of plants, the bitter flavor of alkaloids is believed to be a natural defense in plants to prevent them being eaten by herbivores, similar to cannabinoids and terpenes which both assist in preventing predation. 

    While cannabinoids like THC, CBD, CBG, and THCv, are oily, lipohpilic (binds to fats), and hydrophobic (do not bind to water) compounds, alkaloids are a very different class of chemicals. The biggest chemical difference between alkaloids and cannabinoids is that all alkaloids include a nitrogen atom which binds to additional hydrogen atoms. Cannabinoids, on the other hand, do not have any nitrogen atoms and contain a chain of carbon atoms, which gives them their oily character. 

    Courtesy Duke University

    Despite their differences, efficient methods to extract both alkaloids and cannabinoids from plants is to simply burn the leaves or other parts that contain the chemicals, or perform a chemical extraction. These methods have been used for thousands of years for both types of chemicals; the caffeine in coffee is chemically extracted by brewing with water, cannabis is smoked, and cocaine was originally extracted through chewing or brewed as a tea. 

    Discovery of Alkaloids in Cannabis

    Cannabis is a very complicated plant and “more than 500 compounds have been reported from C. sativa, of which 125 cannabinoids have been isolated and/or identified as cannabinoids.” Non-cannabinoid constituents of cannabis include “42 phenolics, 34 flavonoids, 120 terpenes and 2 alkaloids.” Though, there is some debate over the number of alkaloids which have been identified.

    The discovery of alkaloids in cannabis actually manages to predate the discovery of the first cannabinoid, CBN, back in 1896, by more than a decade. In 1881, the first research on the alkaloid cannabinine was presented at the British Pharmaceutical Conference, and two years later another physiologically active alkaloid, tetanocannabin, was discovered. Cannabis alkaloid research then remained dormant until the 1970s.

    In 1971, a group of scientists isolated four different alkaloids from cannabis, which they named cannabimines A-D. In 1975, two teams of researchers at the University of Mississippi (UMiss) identified and isolated the first spermidine alkaloid, cannabisativine, from the roots, leaves, and stems of both Mexican and Thai cultivars. The next year, the same researchers at UMiss isolated the second spermidine alkaloid, anhydrocannabisativine and showed that cannabisativine could be converted to anhydrocannabisativine. 

    While the cannabis alkaloids cannabisativine and annhydrocannabisativine were first discovered in Mexican and Thai cultivars, anhydrocannabisativine has since been “found in plant samples of Cannabis from 15 different geographical locations.”

    Which Part of The Plant Has the Most Alkaloids?

    Just like how not every part of a cannabis plant has the same amount of cannabinoids, alkaloids are also unequally distributed around the plant. Research has repeatedly shown that, “cannabis roots are not a significant source of cannabinoids or the aforementioned terpenes, but are rich in other compounds, including … alkaloids.” So while terpenes and cannabinoids are concentrated primarily in the trichomes on the leaves, cannabis alkaloids are primarily found in the roots (but can be found in the stems and leaves as well). 

    Medical Effects of Cannabis Alkaloids

    While cannabis alkaloids have a lot of medical potential, the specifics of that potential are unknown. In the case of cannabisativine and anhydrocannabisativine, “no pharmacological information is available,” but it is believed that “there are several compounds in cannabis root with potential anti-inflammatory activity, including alkaloids.” 

    Other researchers have noted that, as a class of compounds, “alkaloids may be used as analgesics, antibiotics, anticancer drugs, antiarrhythmics, asthma medications, antimalarials, anticholinergics, bronchodilators, laxatives, miotics, oxytocics, vasodilators, psychotropics, and stimulants,” and that likely includes cannabis alkaloids. One study of cannabis alkaloids found them to “have diuretic, analgesic, anticancer, antipyretic, and antiemetic effects.”

    In one study, a petroleum ether solution of cannabis alkaloids and cannabinoids had “a course of action comparable to that of atropine,” a drug commonly given to reduce fluid in the respiratory tract during surgery, which “can also treat insecticide or mushroom poisoning.” It is not clear to what extent those observed effects were due to the alkaloids or the cannabinoids. 

    A Quick Hit

    Despite being one of the most common groups of medicinal chemicals found in plants, alkaloids are some of the least known chemicals in cannabis. Early research shows that they may have strong medical benefits as part of the entourage of medicinal compounds in cannabis. 

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    Mitchell Colbert

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  • Caffeine’s Dirty Little Secret

    Caffeine’s Dirty Little Secret

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    On Tuesday, curiosity finally got the best of me. How potent could Panera’s Charged Lemonades really be? Within minutes of my first sip of the hyper-caffeinated drink in its strawberry-lemon-mint flavor, I understood why memes have likened it to an illicit drug. My vision sharpened; sweat slicked my palms.

    Laced with more caffeine than a typical energy drink, Panera’s Charged Lemonade has been implicated in two wrongful-death lawsuits since it was introduced in 2022. Though both customers who died had health issues that made them sensitive to caffeine, a third lawsuit this month alleges that the lemonade gave an otherwise healthy 27-year-old lasting heart problems. Following the second death, Panera denied that the drink was the cause, but in light of the lawsuits it has added warnings about the drink, reduced its caffeine content, and removed the option for customers to serve themselves.

    All the attention on Panera’s Charged Lemonade has resurfaced an age-old question: How much caffeine is too much? You won’t find a simple answer anywhere. Caffeine consumption is widely considered to be beneficial because it mostly is—boosting alertness, productivity, and even mood. But there is a point when guzzling caffeine tips over into uncomfortable, possibly unhealthy territory. The problem is that defining this point in discrete terms is virtually impossible. In the era of extreme caffeine, this is a dangerous way to live.

    Most people don’t have to worry about dying after drinking Charged Lemonade. The effects, though uncomfortable, usually seem to be minor. After drinking half of mine, I was so wired that I couldn’t make sense of the thoughts ricocheting around my brain for the next few hours. Caffeine routinely leads to jitteriness, nervousness, sweating, insomnia, and rapid heartbeat. If mild, such symptoms can be well worth the benefits.

    But consuming too much caffeine can have serious health impacts. High doses—more than 1,000 milligrams a day—can result in a state of intoxication known as caffeinism. The symptoms can be severe: People can “develop seizures and life-threatening irregularities of the heartbeat,” and some die, David Juurlink, a toxicology professor at the University of Toronto who also works at the Ontario Poison Centre, told me. “It’s one of the dirty little secrets, I’m afraid, of caffeine.” Juurlink said he occasionally gets calls about people, typically high-school or college students, who have ingested multiple caffeine pills on a dare or in a suicide attempt.

    You’re unlikely to ingest that much caffeine from beverages alone, yet the increasing availability of highly caffeinated products makes it more of a possibility than ever before. Besides Panera’s Charged Lemonade, dozens of energy drinks contain similar amounts of caffeine, and some come in candy-inspired flavors such as Bubblicious and Sour Patch Kids. Less potent but highly snackable products include caffeinated coffee cubes, energy chews, marshmallows, mints, ice pops, and even vapes. Consumed quickly and in rapid succession, these foods can lead to potentially toxic caffeine intake “because your body hasn’t had time to tell you to stop,” Jennifer Temple, a professor at the University of Buffalo who studies caffeine use, told me.

    More than ever, we need a way to track our caffeine consumption, but we don’t seem to have any good options. In all of the lawsuits against Panera, the basic argument is this: Had the company more adequately warned customers of the drink’s caffeine content, perhaps no one would have been hurt. But most of us just aren’t used to thinking about caffeine in numerical terms the way we do with calories and alcohol by volume (ABV). Caffeine intake is generally something that’s not measured but experienced: I know, for example, that a double espresso from the office coffee machine will give me the shakes. But even though I knew how much caffeine is in a Charged Lemonade, I had no idea how much of it I could drink before having the same reaction.

    The FDA does have a recommended daily caffeine limit of 400 milligrams, the equivalent of about four or five cups of coffee. “Based on the relevant science and information available,” a spokesperson told me, consuming that much each day “does not raise safety concerns” for most adults, except for people who are pregnant or nursing, or have concerns related to their health conditions or the medication they take. The agency, however, doesn’t require food labels to note caffeine content, though some companies include that information voluntarily.

    But the numbers are helpful only up to a point. The FDA’s daily recommendation is a “rough guideline” that can’t be used as a universal standard, because “it’s not safe for everybody,” Temple said. For one person, 237 milligrams could mean a trip to the hospital; for another, that would just be breakfast. The effect of a given caffeine dose “varies tremendously from person to person based upon their historical pattern of use and also their genetics,” Juurlink told me.

    Although people generally aren’t aware of the amounts of caffeine they consume, they tend to develop a good sense of how much they can handle, Temple said. But usually, this knowledge is product-specific; when trying a new caffeine product, the effect can be hard to predict. Part of the problem is that the amount of caffeine in products varies dramatically, even among drinks that may seem similar: A 12-ounce Americano from McDonald’s contains 71 milligrams of caffeine, but the same drink at Starbucks contains 150 milligrams. The caffeine in popular energy drinks ranges from 75 milligrams (Ocean Spray Cran-Energy) to 316 milligrams (Redline Xtreme), according to the Center for Science in the Public Interest.

    Contrast this with alcohol, which tends to be served in conventional units regardless of brand: a can of beer, a glass of wine, or a shot of liquor, all of which have roughly the same ability to intoxicate. Having a standard unit to gauge consumption isn’t foolproof—consuming too much alcohol is still far too easy—but it is nevertheless helpful for thinking about how much you’re ingesting, as well as the differences between beverages. Without such a metric for caffeine, consuming new beverages takes on a daredevil quality. Sipping the Charged Lemonade felt like venturing into the Wild West of caffeine.

    The reason we aren’t good at thinking about caffeine is that historically, we’ve never really had to think that hard about it. Sure, one too many espressos might have occasionally put someone over the edge, but caffeine was consumed and sold in amounts that didn’t require as much thought or caution. “A generation ago, you didn’t have all these energy drinks,” so people didn’t grow up learning about safe caffeine consumption the way they may have done for alcohol, Darin Detwiler, an food-policy expert at Northeastern University, told me.

    Compounding the concern is the fact that energy drinks are popular with kids, who are more susceptible to caffeine’s effects because they’re smaller. Kids tend to drink even more when drinks are labeled as highly caffeinated, Temple said, and the fact that they contain huge amounts of sugar to mask the bitter taste of caffeine adds to their appeal. Last year, a child reportedly went into cardiac arrest after drinking a can of Prime Energy—prompting Senator Chuck Schumer to call on the FDA to investigate its “eye-popping caffeine content.”

    Nothing else in our daily diet is quite like caffeine. Certainly people swear by it, and its benefits are clear: Research shows that it can improve cognitive performance, speed up reaction time, and boost logical reasoning, and it may even reduce the risk of Parkinson’s, diabetes, liver disease, and cancer. But for a substance so ubiquitous that it’s called the most widely used drug in the world, our grasp of how to maximize its benefits is feeble at best. Even the most seasoned coffee drinkers sometimes unintentionally get too wired; as new, more highly caffeinated products become available, instances of caffeine drinkers overdoing it will probably become more common. Perhaps the best we can do is learn how much of each drink we can handle, one super-charged sip at a time.

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    Yasmin Tayag

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  • When To Drink Coffee For The Biggest Effect

    When To Drink Coffee For The Biggest Effect

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    Coffee is a must have for the well being of a large percentage of people. Whether you need it to function in the morning, midday or both, coffee helps us concentrate and get work done. But it also has some negative side effects, especially if you overdo it.

    Caffeine is present in a lot of beverages, piling on throughout the day if you’re not careful. Having too much of it could result in a brain that’s overexerted, anxiety, muscle twitches and that insomnia that strikes if you have a coffee past 6 p.m.

    RELATED: 9 Things That Happen To Your Body When You Drink Too Much Coffee

    Photo by Fahmi Fakhrudin via Unsplash

    On average, the energy that coffee provides lasts for a good six hours, but it can be influenced by a variety of factors. According to The Huffington Post, your age, biology and relationship with coffee could explain why coffee didn’t have as strong of an effect when you were a kid as it does now.

    RELATED: Science Does Not Support Your Coffee Addiction—Here’s How To Choose The Healthiest Cup

    “What we’re learning is every cell of our body has its own biological clock. If you use caffeine… to wake your brain up, it doesn’t necessarily mean the rest of your body is on the same time zone. You may be up, but you may feel sluggish,” said Zhaoping Li, professor of medicine at the University of California, to The Huffington Post. “How our body responds to food, nutrients, including caffeine, it is highly variable. Each individual may have their own sweet spot.”

    this is how much coffee is safe to drink each day
    Photo by Sara Johnston via Unsplash

    As much as coffee’s effectiveness varies, according to The Healthy, for a large percentage of people the best time to have coffee is in the afternoon. This is due to the fact that the minute you wake up, your body is high on cortisol, the stress hormone. This element makes you feel alert, but also a little rough, which is why the world is not full of morning people.

    RELATED: What Too Much Coffee Can Do To Your Endocannabinoid System

    Drinking your coffee mid-morning will provide you with that much needed energy. Says Sherry Ross, MD: “The studies are inconsistent, but it’s thought that waiting until mid-morning—when cortisol levels are lower—is better since caffeine increases this feel-good hormone later in the day.”

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    Amy Hansen

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  • Caffeinated Haircare Products Unlock Crazy-Fast Hair Growth—Here’s Why

    Caffeinated Haircare Products Unlock Crazy-Fast Hair Growth—Here’s Why

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    According to board-certified dermatologist and founder of Facet Dermatology, Geeta Yadav, MD, caffeine offers multiple benefits to the hair and scalp. First, it functions as an antioxidant. “As an antioxidant, it helps defend hair and scalp from free radical damage, allowing for smoother, shinier, and healthier-looking hair,” she says.

    That being said, she admits that the “most interesting” benefit is that it can help with hair growth, which it does by stimulating and actually enhancing blood flow. “In a study, caffeine showed the ability to improve skin barrier function, stimulate blood circulation, and promote new hair growth. It also inhibits phosphodiesterase, which means it can enhance blood flow, too, making for an excellent foundation for healthier hair growth.” 

    Why is blood flow important, According to Brendan Camp, MD, double board-certified dermatologist, “Better blood circulation on the scalp may improve oxygenation and the delivery of nutrients to hair follicles.” In turn, “Improved oxygenation and delivery of vitamins and nutrients to hair follicles may reduce the impact of oxidative stress on hair follicles. Oxidative stress refers to the damage caused by free oxygen radicals, which can have a negative effect on cellular structures.” In other words, more blood flow means more nutrients and less damage to hair follicles. And as we all know, happy hair follicles result in strong, shiny hair. 

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    Kaitlyn McLintock

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  • How To Tell If You Are Sensitive To Caffeine

    How To Tell If You Are Sensitive To Caffeine

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    Caffeine is everywhere, from coffee to soda. So many of us need it to function in the morning to make us feel productive and awake. But there’s a lot of people who have a propensity for feeling very intense reactions when consuming caffeine, which can cause them jitters, sleep issues, headaches, and more.

    Caffeine sensitivity tends to be pretty easy to notice, but sometimes, the symptoms aren’t all that clear. When experienced, it may be uncomfortable to a manageable degree, or it might simply make you feel terrible. If the latter is the case, coffee might not be the drink for you.

    Photo by Priscilla Du Preez via Unsplash

    In order to know whether you experience caffeine sensitivity or not, Healthline recommends keeping a food and drink log to help you realize how much caffeine you are consuming and whether or not it produces some side effects. So you have an understanding of what caffeine sensitivity looks like, here are some of the most common symptoms that people who are sensitive to caffeine experience:

    Your face gets hot

    You Should Wait This Long Before Drinking Your Morning Coffee
    Photo by Priscilla Du Preez via Unsplash

    RELATED: Here’s When You Should Drink Coffee For Maximum Productivity

    A lot of people with caffeine sensitivity experience a hot or flushed face right after consuming a good serving of caffeine. This experience can result in people feeling flushed and even sweaty.

    You have to use the bathroom often

    Photo by Terry Vine/Getty Images

    Caffeine has an effect on the GI tract, meaning it can result in a lot of unwelcome visits to the bathroom. It’s not know how or why this happens, whether it’s a shift in hormones or some elements that are present in coffee, people just know that this occurs with surprising frequency. Another symptom is experiencing the urge to pee more often; since caffeine is a natural diuretic, people with a sensitivity to coffee may find themselves in the bathroom for a whole bunch of reasons.

    You can’t sleep

    3 Tricks That Can Help You Understand Your Sleep
    Photo by Mert Kahveci via Unsplash

    RELATED: 3 Tricks That Can Help You Understand Your Sleep

    Some people need to cut off their coffee intake earlier on in the day since it messes with their sleep patterns. A sip of coffee can leave them jittery and wired for hours after they consumed it. While annoying, this symptom is manageable if people cut off their coffee intake early, having their last sip of coffee no later than around 4 p.m.

    You feel uneasy or anxious

    Sleeping Too Little May Increase This Group's Risk Of Dementia
    Photo by Bruno Aguirre via Unsplash

    Some of us feel more anxious after consuming our coffee, something that might go unnoticed since it’s usually early and we have to deal with a variety of stressors, like getting to work on time and completing our commute. There’s a reason for this — caffeine increases your stress hormones. Like stress itself, caffeine results in an increased heart rate and in higher blood pressure.

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    Maria Loreto

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  • Chuck Schumer Calls On FDA To Investigate 72-Hour Erection He Got From Prime Energy Drink

    Chuck Schumer Calls On FDA To Investigate 72-Hour Erection He Got From Prime Energy Drink

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    WASHINGTON—Calling the influencer-backed beverage a serious public health concern, a visibly erect Sen. Chuck Schumer (D-NY) called on the FDA Monday to investigate the 72-hour erection he had experienced as a result of drinking Logan Paul’s Prime energy drink. “Buyers and parents need to understand the risks involved with having a three-day stiffy that’s as hard as a mallet,” said the Senate Minority Leader, who winced as he pulled at his pants from behind the podium, confirming that his erection remained unchanged despite repeated efforts to take a cold shower, masturbate, and make love to his wife, Iris. “After drinking just one can of this stuff last week, I still feel the effects of arousal, to the point that I cannot physically urinate without leaning over the toilet. It’s just throbbing down there, and I’m worried it’s here for good. Durbin took a sip, too, and look at him—he can’t even sit down. This beverage, marketed simply as a ‘hydration supplement’ has no business being on U.S. shelves. I am begging the FDA: Please, for the love of God, investigate my penis.” At press time, Schumer was overheard explaining to the Senate Ethics Committee that his bulging erection was not sexual, but rather a physiological response to blue raspberry flavoring.

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  • I Thought Long and Hard: These Are the 13 Best Items on J.Crew Right Now

    I Thought Long and Hard: These Are the 13 Best Items on J.Crew Right Now

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    I needed to talk to someone about some shopping finds that are on my radar, and when that’s the case, it’s my duty to write a story about it. Specifically, I need to talk about J.Crew. We cover J.Crew quite a lot here at Who What Wear these days because it’s excellent and worthy of discussion, but I wanted to do a story about a few very special items that are part of its inventory right now.

    So, instead of the usual 30 or so items of note at J.Crew right now, I’m here to talk about just 13. Why? Because I want to focus the attention, sans distractions, on a handful of items that are all equally stylish, versatile, compliment-worthy, and just plain cool. It’s a mix of summer-friendly basics and trend-forward pieces, all of which promoted me to immediately hit the “add to cart” button. Trust me, you’re going to understand why I chose these items when you see them/.

    Intrigued by my J.Crew passion? Keep on scrolling. 

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    Allyson Payer

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  • High Caffeine Levels Linked to Lower Body Fat, Diabetes Risk

    High Caffeine Levels Linked to Lower Body Fat, Diabetes Risk

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    March 17, 2023 — Having a higher level of caffeine in your blood could reduce body fat and the risk of type 2 diabetes, according to a new study published in BMJ Medicine. 

    Although additional research is needed, the findings open possibilities about the role that calorie-free caffeinated drinks could play in lowering the risks for obesity, diabetes, and other conditions.

    “Caffeine has been implicated in affecting metabolism and is commonly consumed in drinks. It is therefore important to better understand what causal effect it might have on metabolism,” said senior study author Dipender Gill, PhD, professor of epidemiology at Imperial College London.

    “However, we would like to emphasize that individuals should not change their dietary preferences or lifestyle based on the findings of our study alone,” he said. “Further validation in the form of clinical trials is warranted first. Furthermore, too much caffeine can also have harmful effects, so a balance is necessary.”

    Previous studies have found that drinking 3-5 cups of coffee per day is associated with a lower risk of type 2 diabetes and heart disease and drinking 100 milligrams of caffeine per day can increase energy expenditure by about 100 calories per day. An average cup of coffee contains about 70-150 milligrams of caffeine.

    However, most of the published research has focused on observational studies, which don’t prove cause and effect. Plenty of other factors could be involved, including other ingredients in caffeinated drinks and foods, according to lead author Susanna C. Larsson, PhD, of the Karolinska Institute in Stockholm, Sweden, and colleagues.

    Katarina Kos, MD, PhD, a senior lecturer in diabetes and obesity at the University of Exeter, UK, agrees. She said that this genetic study “shows links and potential health benefits for people with certain genes attributed to a faster [caffeine] … metabolism as a hereditary trait and potentially a better metabolism.”

    “It does not study or recommend drinking more coffee, which was not the purpose of this research,” she told the U.K. Science Media Centre. Kos wasn’t involved with this study.

    In the new analysis, the researchers examined data from 10,000 people mainly of European ancestry who participated in six long-term studies. 

    They examined two specific genetic mutations that have been linked to a slower speed of caffeine metabolism. In general, people with these two common genetic variants will have higher levels of caffeine in their blood after consuming coffee, or other caffeinated drinks, than those with faster caffeine metabolism.

    They then looked at how caffeine levels tracked with body fat, risk of type 2 diabetes, and risk of major heart conditions such as coronary artery disease, stroke, heart failure, and irregular heart rhythm.   

    The two gene variants resulted in “genetically predicted, lifelong, higher plasma caffeine concentrations,” the researchers note “and were associated with lower body mass index and fat mass, as well as a lower risk of type 2 diabetes.”

    There weren’t any strong associations in this study with a lower risk of developing any of the major heart conditions.

    They found that weight loss contributed to about 43% of the effect of caffeine on type 2 diabetes risk.

    “The finding that higher plasma caffeine levels may reduce bodyweight and risk of type 2 diabetes seems to fit with what is known about its effects on metabolism,” Gill said. “We are now exploring the broader effects of caffeine on health outcomes and potential mechanisms that may be mediating this.”

    The researchers noted several limitations, including that they only studied two genetic variants and that the study participants had predominantly European ancestry. They also emphasized caution about drawing strong conclusions or changing behaviors.

    Kos agrees. “When considering coffee consumption and caffeine-containing energy drinks, one must be mindful of the potential negative offset by surplus calories in the form of sugar and fat in many of these drinks,” she noted. 

    “Even for the option of increasing the use of calorie-free caffeine drinks, a benefit has yet to be proven,” Kos said. 

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  • Should I drink sugar-free fizzy drinks every day? – Catherine Saxelby’s Foodwatch

    Should I drink sugar-free fizzy drinks every day? – Catherine Saxelby’s Foodwatch

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    Sugar-free soft drinks, which have been around in various forms for almost 40 years, still have their problems. Remember Tab? Remember Coke Zero? Yes, they tasted sweet and saved you drinking some 40 teaspoons of sugar from each 375 ml can, but are they really healthier than regular soft drinks?

    Brownie points

    When you choose a diet drink, you may end up indulging in other sweet, kilojoule-dense options because you’ve been ‘good’. So, you’ll often see someone sipping a sugar-free drink while eating a chocolate bar, croissant or brownie. It confuses our brains.

    Weight loss … or weight gain?

    Sugar substitutes do little in the way of weight loss. In fact, the opposite may be true: some diet-beverage drinkers gain weight and have an increased risk of chronic diseases.

    A 2010 study published in Physiology & Behavior concluded that regularly consuming sugar-sweetened drinks could lead to weight gain and an increased risk of developing type 2 diabetes.

    In 2013, however, researchers had 200 people replace their sugary drinks with diet varieties or water for 6 months. Their conclusion? The sugar-free-beverage drinkers actually ate fewer desserts than the water drinkers. So there’s that.

    A too-sweet taste?

    When you drink them regularly, no-sugar soft drinks get you used to a sweet taste. This is a long-term problem for weight loss, as well as for people with type 2 diabetes, metabolic syndrome and cardiovascular disease. If your body is used to getting a super-sweet hit from diet soft drinks, it makes managing appetite much more difficult.

    The sweetness signal tells our bodies to prepare for kilojoules (or calories) and our appetite is generated in readiness, but no kilojoules arrive. So we’re likely go out and consume other foods. In other words, sweeteners prep our bodies for a sugar fix but then don’t deliver. So sweeteners interfere with the learned responses that normally contribute to glucose and energy homeostasis.

    Bubbles on a glass of sugarfree cola

    How safe are they?

    We know these sweeteners are safe, but what we don’t know are their long-term effects on appetite. So let’s just say, the scientific jury is still out on their long-term effects.

    The bottom line

    The key is only having sugar-free soft drinks as an occasional treat, not every day or when you feel thirsty. Long term, we don’t really know what these sweeteners are doing to our bodies. One or two is fine (say, if you’re going out to a club), but regularly consuming these zero-sugar drinks may lead to long-term overconsumption of other foods.

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    Foodwatch

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