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Category: Cannabis

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  • Drink to Your Health | High Times

    Drink to Your Health | High Times

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    In California, it’s called Cali sober, but all over the world people are switching from alcohol to cannabis-infused beverages, purposefully doing away with drunkenness, cognitive fumbling, and stumbling—and possibly that walk of shame the next morning—along with the hangovers. Harm reduction is the new buzzword for switching to weed, with people across the country choosing the plant over booze, stating it makes them better people, parents, and partners.

    A Nose for Flavor

    Wine specialist and sommelier turned cannabis beverage connoisseur, Jamie Evans, founded The Herb Somm in 2017. The blog and lifestyle brand hosts high-end, gourmet cannabis-infused dinners curated with wine and cannabis. Her first book, The Ultimate Guide to CBD: Explore the World of Cannabidiol, was released in 2020 and features recipes infused with CBD. Her second book, Cannabis Drinks: Secrets to Crafting CBD and THC Beverages at Home, was released in 2021.

    “Cannabis drinks are a fantastic alternative to alcohol,” Evans said. “With the new low-dose options that are now available, these beverages can offer a similar experience to drinking one glass of wine or a beer, but without the hangover. Market trends are also showing that more consumers are seeking alternatives to alcoholic beverages for health reasons, which has been driving new curious consumers to the cannabis drinks category.”

    In 2021, Evans launched Herbacée, a cannabis-infused beverage company, “celebrating flower and vine.” Evans said the iconic wine regions of France inspired Herbacée. The non-alcoholic cannabis beverage blends phytocannabinoids (cannabinoids derived from plants), terpenes (aromatic compounds which contribute to taste and smell), tannins (a bitter, astringent compound found in things like wine), and terroir (characteristic tastes imparted by the natural environment).

    “In researching cannabis, I came across many similarities between the plant and wine, including farming practices and sensory evaluation techniques,” Evans said. “Mixology is defined as the skill of mixing cocktails and other drinks, but at its core, it’s the extensive study of the art and craft of combining flavors.”

    Courtesy of Jamie Evans

    Cannabis Cocktails

    With her new drinks guide, Evans offers recipes, tips, and tricks in making cannabis-infused craft cocktails, smoothies, lattes, and spirit-free mixed drinks at home. Basic infusions include making age-old bitters, honey, sour mix, simple syrups, and alcohol-based tinctures. Using a technique she calls “infused mixology,” the book teaches the basic building blocks of crafting marijuana mocktails.

    “One of the most important things to making a good cocktail is balance,” Evans said. “As with all drinks, we must evaluate whether the drink is too sweet or too sour? Is it complex or simple? What’s the texture like? How can you make this drink more intriguing and palatable? Once you can achieve balance, you’ve created a good cocktail. Also, remember that every ingredient that goes into the beverage is meant to enhance the complexity, structure, mouthfeel, and backbone.”

    Evans
    Courtesy of Jamie Evans

    The Future is Fluid

    Evans is excited for more people to try their hand at making cannabis cocktails.

    “I am enthusiastic about the future of cannabis cuisine, cannabis restaurants, and cannabis-infused beverage bars,” she said. “In my opinion, making your own infusions, such as cannabis-infused simple syrup or cannabis-infused bitters, is the best method to use since it allows you to customize the infusion based on your personal preferences.”

    Cannabis infusions will also combine into drinks seamlessly versus using a commercially-made oil tincture. Evans said the only downside with making your own infusions is calculating the dosage. With homemade creations, the milligram count will never be as precise as using a professionally-made product.

    If you don’t have time to create your own infusions, Evans suggests adding an alcohol or oil tincture to infuse drinks.

    “Dosing in this way is easy when using a measured tincture or water-soluble formulations that have already been tested with protocols,” she said. “CBD isolates using just one compound from the plant, cannabidiol, are another way to infuse a beverage. They are typically flavorless, odorless and are a fast and potent way to integrate CBD into your regime.”

    Evans noted consumers can also utilize beverages already infused with THC or CBD right off the shelf, adding the pre-made infusions to their mocktails for another quick mix. She said the most important thing is to make sure everything used can be well blended, mixed, stirred, shaken, or muddled (mashing plants, such as mint or fruit in the bottom of a glass).

    Evans said those interested in crafting their own cannabis cocktails can begin by making tasting notes for each ingredient and should not shy away from the herbaceous taste of weed.

    “When working with cannabis in a cocktail, don’t mask the flavor of cannabis, complement it,” she said. “A lot of producers add a ton of sugar to drinks that cover the flavors of cannabis. Instead, if you focus on using terpene-inspired ingredients, they will play well with cannabis flavors and your drinks will taste delicious!”

    theherbsomm.com

    Evans’ book Cannabis Drinks: Secrets to Crafting CBD and THC Beverages at Home contains a wealth of knowledge regarding how to take the guesswork out of making quality homemade cannabis beverages. Here are two recipes from the book.

    Evans
    Courtesy of Jamie Evans

    Ginger Rabbit

    Packed with nutrients, vitamins, and minerals, fresh carrot juice adds delicious flavors to drinks and can help improve your immune system, increase your metabolism, and help lower cholesterol. Carrot juice also pairs well with many other fruits, vegetables, roots, and herbs, making it a wonderful item to mix with. Introducing the ginger rabbit: Give this recipe a try when you’re in need of some extra nutrients to help support your immune system or anytime you’re in the mood for an incredibly refreshing drink!

    Yield: 1 serving
    Target Dose: 8 mg CBD | 2 mg THC per drink (using infused ginger simple syrup), or your preferred dose (using a commercially made CBD or THC tincture of your choice)

    Equipment:
    Muddler
    Shaker tin
    Fine-mesh strainer
    Collins glass
    Bar spoon
    Reusable straw

    Ingredients:
    1 (1-inch or 2.5-cm) piece fresh ginger, peeled and sliced
    2 ounces (60 ml) fresh-pressed apple juice
    4 ounces (118 ml) fresh-pressed carrot juice
    1 1/2 ounces (45 ml) fresh lemon juice
    1/2 ounce (15 ml) infused ginger simple syrup 
    Ice
    Splash of ginger beer 
    Carrot greens, edible flowers, and a slice of lemon for garnish

    Directions:
    Muddle the ginger and apple juice at the bottom of a shaker tin. Muddle well to extract as much ginger flavor as possible. Add the carrot juice, lemon juice, and infused ginger simple syrup. Add ice, cover, then shake for 15 seconds or until very cold.

    Using a fine-mesh strainer, separate the solids from the liquids over a Collins glass filled three-quarters with fresh ice. Top with a splash of ginger beer, give it a good stir with a bar spoon, then garnish with a sprig of carrot greens, edible flowers, and a slice of lemon. This drink is best enjoyed with a reusable straw.

    Note: When making spirit-free mixed drinks, it’s best to stick with healthier options and avoid extra sugar. I always recommend using fresh-pressed juices over concentrates and to source seasonal ingredients so that you’re working with the freshest produce possible. The same goes for ginger beer—the quality matters. I recommend using Q Ginger Beer because of its extra carbonation and spicy but not overly sweet flavor. Avoid using mixers that contain high fructose corn syrup or a ton of added sugar. These additives can drastically change the drink’s profile. If you don’t have the supplies to infuse the ginger simple syrup, simply substitute for regular simple syrup, then add your favorite unflavored tincture (at your preferred dose) into the shaker tin before muddling. Follow the directions as written.

    Infused Ginger Simple Syrup

    Yield: about 15 to 16 ounces (465 to 480 ml)
    Target Dose: 16 mg CBD | 4 mg THC per ounce (using a flower infusion)

    Equipment:
    Digital scale
    Peeler
    Measuring cups
    Measuring spoons
    Small saucepan
    Thermometer
    One 16-ounce (480-ml) sterilized Mason jar
    Cheesecloth
    Fine-mesh strainer

    Ingredients:
    3 grams decarboxylated flower of your choice
    2 cups (480 ml) water
    1 cup (340 g) honey
    1 1/2 heaping tablespoons fresh ginger, peeled and sliced into pieces 
    1 tablespoon (15 ml) food-grade vegetable glycerin

    Directions:
    Weigh out 3 grams of decarboxylated flower. Set aside.

    Combine the water, honey, and ginger in a small saucepan. Bring to a soft boil, stirring until the honey dissolves into the water. Reduce the heat to around 160°F to 180°F (71°C to 82°C) and add the decarboxylated cannabis.

    Simmer over low heat for 50 minutes, stirring occasionally. Reduce the heat and add the vegetable glycerin—this will give the CBD (and THC) something to bind to. Continue to heat and stir for 10 minutes. Remove from the heat.

    Pour the infused simple syrup into a 16-ounce (480-ml) Mason jar through cheesecloth placed in a fine-mesh strainer to remove the solids. Let cool and shake before serving.

    This article appears in the June 2022 issue of High Times. Subscribe here.

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    Sharon Letts

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  • University of Kentucky Opens New Cannabis Research Center

    University of Kentucky Opens New Cannabis Research Center

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    The Bluegrass State’s flagship university is getting some green. In an announcement on Wednesday, the University of Kentucky heralded the opening of “a new center that will advance research on the medical use of cannabis.”

    The “UK Cannabis Center,” as it is known, “will conduct research on the health effects of cannabis, including its risks and benefits when used to treat certain medical conditions.”

    The center is the result of a bill passed by Kentucky lawmakers and signed into law by Gov. Andy Beshear earlier this year.

    “The legislature is interested in having us explore the conditions for which medical cannabis might be useful, as well as the most effective dosing and route of administration for each condition,” said Dr. Shanna Babalonis, who will serve as director of the UK Cannabis Center.

    The announcement on Wednesday said that Babalonis is “an assistant professor in the Department of Behavioral Science and a cannabis researcher at CDAR, is increasingly recognized as a leader in the cannabis field and an expert on the topic of medical cannabinoids,” boasting “three active National Institutes of Health grants, totaling nearly $3.5 million, aimed at examining cannabis-opioid interactions, cannabis effects in those with opioid use disorder and the effects of cannabis on simulated driving performance.”

    “The new center will allow us to expand our clinical research, particularly focusing on medical conditions that may be helped by medical cannabis,” Babalonis said in the announcement.

    The bill that established the UK Cannabis Center was passed in the closing days of the Kentucky legislative session in April. Beshear, a Democrat, used a line-item veto in his signing of the legislation, striking out certain parts of the bill that he said would “limit the purpose of the center and dictate who the president of the University of Kentucky should consider appointing to the advisory board after giving the president of the university sole appointing power.”

    Beshear said earlier this year that he was entertaining the idea of using executive action to legalize medical cannabis in the state.

    “We’re going to explore that,” Beshear said in April. “It’s something that we will look at. Its time has certainly come.”

    That didn’t sit right with members of legislature, including Kentucky state Senate President Robert Stivers.

    “The public should be concerned with a governor who thinks he can change statute by executive order,” Stivers said in a statement in April. “He simply can’t legalize medical marijuana by executive order; you can’t supersede a statute by executive order because it’s a Constitutional separation of powers violation.”

    The bill that established the UK Cannabis Center was viewed as a compromise by Republicans in the state Senate who were not ready to fully legalize medical cannabis treatment. A bill legalizing medical cannabis passed out of the Kentucky state House of Representatives in March, but the measure was never brought to a vote in the state Senate.

    In the announcement on Wednesday, the University of Kentucky said that the bill “also requires UK to apply to the U.S. Drug Enforcement Administration for a license to grow and cultivate cannabis,” and that if approved, “the center will be able to conduct agricultural research pertaining to optimal growing conditions.”

    According to the announcement, “UK President Eli Capilouto recently appointed a multidisciplinary team of UK faculty members that will oversee the research center’s work and finances,” and the “12-member board includes an executive or steering committee that will work with Babalonis to establish the center’s research goals and agenda and make key financial decisions, and an advisory board to help guide and provide feedback on the center’s progress and overall direction.”

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    Thomas Edward

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  • Researchers Studying Psychedelic Drug as Treatment for Alzheimer’s Disease

    Researchers Studying Psychedelic Drug as Treatment for Alzheimer’s Disease

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    A Toronto-based biotech company is researching a new psychedelic drug as a treatment for Alzheimer’s disease, noting in a recent announcement that it has received approval from regulators in Argentina to commence a Phase ll clinical trial of the company’s novel psychedelic compound, BMND08.

    “As we continue to move forward with our efforts in identifying indications where we can provide significant improvement in patients suffering from mental health, we are more than pleased to announce the approval of a Phase II clinical trial for our BMND08 novel drug candidate which may allow us to address a new line of development to attenuate depression and anxiety states in patients with Alzheimer’s-type cognitive impairment,” Alejandro Antalich, CEO of Biomind Labs, said in a statement from the company.

    Biomind Labs is a biotech research and development company that is studying novel drugs and innovative nanotech delivery systems for a variety of psychiatric and neurological conditions. Using its technology, the company is developing new pharmaceutical formulations of the main psychedelic molecules, N,N-Dimethyltryptamine, 5-MeO-DMT, and mescaline for the potential treatment of a wide range of therapeutic indications, with a focus on providing patients access to affordable and groundbreaking treatments.

    “Since our inception, neurodegenerative diseases were on the list of indications we wanted to tackle. We can now address such indications using a novel approach that uses a fast-acting psychedelic molecule capable of providing relief to certain mood states when Alzheimer’s disease first appears in patients,” said Antalich. “After a thorough analysis on the potential benefit of using a psychedelic molecule to alleviate certain symptoms in Alzheimer’s patients, we concluded that the most suitable candidate from our portfolio was BMND08, an oral formulation of 5-MeO-DMT.”

    Nearly Six Million American Seniors Live with Alzheimer’s

    Alzheimer’s disease is a progressive neurological disorder that causes brain cells to atrophy and die. Nearly six million people in the United States aged 65 and older live with the disease, according to information from the Mayo Clinic. The disease is the most common cause of dementia, a continuous decline in cognitive function and social skills that affects the ability to function independently. Although medications may temporarily improve or slow the progression of symptoms, there is no cure for Alzheimer’s disease. In advanced stages of the disease, complications from significant loss of brain function such as dehydration, malnutrition or infection result in death.

    “Given the significant morbidity rate associated with Alzheimer’s disease such as agitation, apathy, sleep disturbances and anxiety, it became clear to us that novel approaches to treat Alzheimer’s-type cognitive impairment are urgently needed,” Antalich said. “The Phase II clinical trial will test Biomind’s psychiatry intervention-based model, allowing a rapid and feasible merge of fast-acting psychedelic medicines into clinical practices already in existence.”

    The research is studying whether BMND08, a drug based on the natural psychedelic compound 5-Methoxy-N,N-dimethyltryptamine (also known as 5-MeO-DMT or simply DMT), is effective as a treatment for the depression and anxiety commonly found among patients with Alzheimer’s disease. The Phase ll clinical trial will be conducted in Argentina, where regulators gave approval for the study in May.

    Previous studies have shown that more than 60% of patients with Alzheimer’s disease have also been diagnosed with depression. Treating a patient’s depression may also help treat or delay other symptoms associated with Alzheimer’s disease. An unrelated study showed that the antidepressant called imipramine may be effective in treating cognitive decline in patients with the condition. Although some research has studied cannabis as a possible treatment for the symptoms of Alzheimer’s disease, Biomind’s study is believed to be the first to test a psychedelic like DMT.

    “While the current practice guidelines consistently refer to the management of symptoms as central to the treatment of Alzheimer’s disease, the lack of established effective treatments continues to motivate us to generate novel therapeutic solutions,” said Antalich.

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    A.J. Herrington

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  • How to Increase Terpene Levels in Your Cannabis Plant! | Crop King Seeds | Crop King Seeds

    How to Increase Terpene Levels in Your Cannabis Plant! | Crop King Seeds | Crop King Seeds

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    The citrus of an orange rind. The smell of lavender as the wind stirs it in its fields. 

    The aromatic moments that we’ve grown to love in the world around us are largely derived from compounds known as terpenes. Terpenes give not just plants their famous scents and flavors, but also cannabis.

    An introduction into the world of cannabis requires, at a very basic level, an understanding of terpenes. Terpene profiles differentiate one strain from the next, offering expanded experiences based upon the needs of the consumer or the goals of the grower.

    Today, we are going to explore the world of terpenes, what they do, and how to inspire further production in your cannabis garden at home.

    So, What ARE Terpenes?

    Put plainly, terpenes are extremely aromatic compounds that offer the smells we associate with plants, herbs, and animals. Terpenes are often isolated and used to flavor and scent many products in our day-to-day life, including bath products and perfumes.

    In nature, terpenes are vital in playing a protective role in the life of the plant, healing and protecting the plant from potential danger. Terpenes also act on behalf of the plant’s immune system, often preventing infectious germs from taking hold.

    Improving Terpene Production in Cannabis

    Terpenes are a natural compound in the world and they are particularly important to the development of high-quality cannabis. Terpenes work directly alongside other cannabinoids, including THC and CBD, to provide a fully-fledged and well-rounded experience for consumers.

    Let’s explore a few different ways that growers can make sure they are developing terpene-rich cannabis by making small adjustments to their methods.

    Amend Your Soil With Nutrients

    If you want to enjoy the cultivation of large, compact, and stinky buds then you will have to learn to embrace sugars and carbohydrates. Carbs primarily operate as the primary source of energy for your cannabis plants, offering energy in lockstep with sugar to contribute to the structure of the plants.

    Creating a rock-solid nutrient schedule that promotes a full feeding of sugar can bring about the development of a richer and more complex terpene profile. Sugar carbs are especially important as the plant enters its flowering stage, where these terpenes are most notable in their effect.

    Focus on High-Quality Genetics

    At the end of the day, much of the terpene development that goes on in your cannabis plant will rely on the genetic code within. High-quality genetics can result in better-quality products, so make sure that you are acquiring your seeds or clones from a reputable source. Some strains are simply predisposed to certain effects. Even the best grower in the world cannot make bagseed look like White Widow!

    Optimize Your Growing Environment

    Light and nutrition are the core factors that coincide with a successful cannabis harvest. If you are looking to successfully grow your cannabis with terpene-rich cannabinoids, you’ll want to offer exceptional light coverage.

    Indoor growers must make sure to carefully cover the entirety of their plants, ensuring that no coverage is lost at the lower levels of their cannabis. Make sure that there is space between your plants for colas to acquire the same amount of sunlight as everywhere else.

    Outdoor growers get to enjoy the natural benefits of excess outdoor lighting, bringing flavorful results that are also aromatic. The natural light of the sun offers a full and complex spectrum to feed your plants.

    Embrace Low-Stress Training

    Trichome and terpene development is often tied to the defense mechanisms of the plant itself, largely against pests and herbivores. Slightly stressing your plants to engage their defense mechanisms is known as Low-Stress Training. Low-stress training is an ideal way to induce minor levels of stress that can dramatically increase your terpene production.

    Begin LST as early as possible, ideally after your plant is in a comfortable vegetative state. Allow the plant to establish a few nodes before beginning the process. Tie down and prune lower branches to help redirect energy to other flowers, causing trichome production to explode.

    Some growers will turn off their lights for 48 hours before the date of harvest to trick the plants into thinking that they are dying. This causes the plants to release the resin in their systems, pushing the sticky production toward those fully-formed buds.

    Low-stress training can be a fantastic way to induce better tasting, smelling, and smoking of cannabis. Make sure that you carefully monitor your garden during this process to prevent any missteps from occurring.

    Don’t Forget to Flush Your Plants

    Roughly two weeks before harvest, you should put an end to feeding your plants. This is known as flushing and it is a way to make sure that you have no toxic nutrient build-up when it comes time to harvest. Flushing the plant will reveal the natural and more robust flavors and aromas hidden behind your feeding schedule.

    Utilizing a pure water source for the final two weeks of the harvest will allow your plant to slowly wash away the nutrients that you’ve fed it with over the prior weeks, leaving you with something clean, fragrant, and potent.

    A proper flush is necessary to maximize terpenes as well as their impact on the final product.

    Improve Your Grow and Embrace Terpene Production

    Developing robust harvests with terpene-rich cannabis requires attention to detail and the willingness to implement a few of our key tips. Prioritize high-quality genetics, maximize light coverage, and embrace low-stress training to make sure that your plants are as exceptional as they can become!

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    colabarmy

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  • The Role of Cannabis in Treating Long COVID

    The Role of Cannabis in Treating Long COVID

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    During a recent (and highly important) call with one of my publishers, I put the call on mute whenever I wasn’t speaking so I could projectile vomit. I was having a migraine, but the call was too important to reschedule. Unfortunately, while they may work for some, Sumatriptan, along with Topamax, Nurtec, and every other migraine medication doctors prescribed me, play into the accompanying nausea and I throw it up before any pain relief for my head (which hurt so badly I wanted to put a bullet through my brain) could set in. While I’m going to continue to see neurologists and (when I can get in, the waitlists are nuts) a long-term COVID specialist, the next time a migraine strikes, I’m sticking with THC gummies, honey. Thank god cannabis is also good for nausea.

    I didn’t have migraines before I had COVID, which I got in 2020 from a friend, shortly after restaurants opened up but before there was a vaccine. I figured if restaurants could open, I could risk this respiratory disease; after all, I’m young, healthy, and never smoked tobacco, I even stick primarily with edibles when it comes to cannabis. What I, and the general public didn’t know, is that COVID affects the brain, too. According to The Washington Post, the blood vessels of our brains are lined with endothelial cells, which have angiotensin-converting enzyme 2 (ACE2) receptors, a type of protein that the coronavirus latches onto. This causes such cells to become inflamed, which harms the blood-brain-barrier, inducing swelling and resulting injury. As a result, me, and many others, now have what’s called long COVID, symptoms or effects of the disease that last weeks, months, or as I can attest to, even years after first exposure.

    “Primarily, what we’re seeing is long-term cognitive consequences,” says cannabis clinician Dr. Mikhail Kogan, who is part of the George Washington University faculty and the author of Medical Marijuana: Dr. Kogan’s Evidence-Based Guide to the Health Benefits of Cannabis and CBD. “Patients present with cognitive decline, and more severe cases present with outright dementia.” He says that common symptoms of long COVID include mood disorders such as depression, anxiety, insomnia, and pain, such as my migraines (which don’t help with anxiety, depression, or insomnia, you can imagine). Hair loss, brain fog, and changes in taste and smell are also common. For some folks, long COVID symptoms are totally out of the blue, but for others, it’s almost as if the SARS CoV-2 virus triggers latent conditions, or health problems they were predisposed to and the infection activated. “What happens a lot is that we uncover other problems when we start working with long COVID patients because we find that they’ve had other problems going on for a long time, but they were very mild, so nobody paid enough attention.”

    Thankfully, as The Washington Post points out, while there are instances of older people getting dementia after exposure, these neurological injuries usually take place in younger folks, between the ages of 20 and 50, who never needed hospitalization. Eventually, the symptoms resolve for some people. But for others, they’re still reeling from the ongoing destruction.

    David, 30, out of Enfield Connecticut, and his partner of 10 years first got COVID in late January of 2020. First, his partner picked it up after traveling across several states to pick up the couple’s new rescue dog, Ellie. David got COVID shortly thereafter. “Fast forward a tad I also get sick, we are bed bound, I needed to use walls and my bed frame to even hold myself up. It was like the flu, mixed with food poisoning, vertigo, and so much more. Jump ahead to 2021, we caught Delta in September,” David says.

    Since then, after they got over “having COVID,” and were no longer contagious, the health problems persisted. “Over the past three years, we have realized a large accumulation of things wrong with us that just weren’t issues before. I have trouble breathing in intense heat and cold and I have a lot of coughing fits. Early results are pointing towards lung scarring. I also have Sleep Apnea, and my brain feels like it [has] aged 10-20 years. I have a horrible short-term memory now. I hurt a lot and am often exhausted,” David says. He adds that his partner has a similar list of symptoms, except more severe, in addition to POTS (Postural orthostatic tachycardia syndrome) and Fibromyalgia. “Saying I am ‘better’ than my partner would be like saying if they were given a knife in a gunfight, but I was lucky because I got two knives in a gunfight,” David says. “I hope that makes sense.” It does. 

    It’s not a happy story. David’s partner lost their job at a farm due to their long COVID symptoms, and he was no longer able to continue his job in consumer and fan services at LEGO mostly because of long COVID brain fog. “My work output was absolutely awful. If it weren’t for my job there, though, I wouldn’t have the healthcare we had access to for the past two plus years with my work insurance. To say that we would be in a worse position without that insurance would be an understatement. Long COVID has taken away A LOT from us,” David wrote to High Times.

    He currently has been able to pick up one-off gigs in the video game industry. David has also found hope somewhere fun other than the video game industry: cannabis. “It helps keep me focused or at least my mind off negative thoughts brought on by long COVID. For me, but much more so for my partner, it helps settle nausea. My partner literally wouldn’t be able to hold down the first meal of the day for a time without taking an edible to help settle their stomach. And sleep, oh do I enjoy actually getting to sleep again since becoming a heavier cannabis user,” David says.

    Cannabis is one of the few long COVID treatments that covers a plethora of symptoms rather than one. “Almost no patients present with one symptom, everybody presents with a package. And that package will usually include three to five symptoms. Cannabis is almost the only treatment I can think of that targets all of the symptoms. If a patient comes in with migraines, insomnia, anxiety, and nausea, it’s four medications versus cannabis,” says Dr. Kogan. He says CBD is the first line, but for most pain you want a little bit of CBG in the mix. Noting that this is based on experience, and more research is needed, he adds that CBG is very effective for chronic neuropathic pain when it’s specifically in the settings of anxiety and depression.

    Unfortunately, this is tough to study. Not only are doctors still learning more about long COVID everyday, and only have a few years to work off of, but trying to get funding for cannabis research sucks until the Feds finally remove the Schedule I label. But don’t worry. As always, the science nerds find a way. In February of 2022, the UK’s NHS Research Ethics Committee and Medicines and Healthcare products Regulatory agency approved one of the world’s first scientific studies on the efficacy of cannabis to treat long COVID. The study is being done by the NGO Drug Science, founded by neuropsychopharmacologist David Nutt, infamous (but correct?) for stating that horseback riding was more dangerous than taking ecstasy.

    Drug Science recently wrapped up their Phase 2 trials. “It’s a feasibility study and we’re half-way through it so I can’t give you any results, but what I can tell you, is that those patients seem to be responding pretty well. There’s no drop out, which is great for a feasibility study. We now have over 3,000 patients who are submitting their data every month to us. What we see through that is that there is a statistically significant improvement in people’s health outcomes since they’ve been prescribed medical cannabis,” Drug Science’s CEO, David Badcock, told High Times over Zoom. They’re giving patients a full-spectrum high-CBD oil, with a small amount of THC, but not enough to produce a high, supported by the company BOD Australia.

    According to Dr. Mikhail Kogan, “Most of our patients recover. And the reason they recover is that we don’t look at this the way medicine does. We don’t just prescribe particular treatment, what we say is let’s try to find out why you have these conditions. Let’s try to fix what’s underneath the symptoms.” The brain’s known for its neuroplasticity, or ability to adapt, change, and heal, so while there are plenty of horror stories, there’s no reason patients shouldn’t hope to get better over time.

    “Cannabis helps elevate me to a place where I can just say, ‘You know what, your whole life has been trauma after trauma; just give this one the bird and help the two of you love and appreciate each day as best as you can,” David says.

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    Sophie Saint Thomas

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  • Lemon Cake strain

    Lemon Cake strain

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    Originally formulated by the European-based company Heavyweight Seeds, Lemon Cake strain (not to be confused with Lemon Cake Kush strain) is a powerful sativa-dominant hybrid that packs just as much potency as it does flavor. 

    Indica / Sativa Indoor yield Outdoor yield Flowering period
    20% – 80% 2.3 oz/ft² 21-28 oz/plant 63-70 days

    With its THC content ranging from 17% to 23%, this flavor-laced strain is highly recommended for daytime use and can be a gentle introduction for cannabis newbies

    Learn more about the Lemon Cake cannabis strain

    Lemon Cake marijuana has a fairly easy-to-grow track record, generating beautiful plants with admirable yields. 

    Any strain with this much to offer – from energizing effects to a delectable lemony-cheese flavor – is sure to keep cannabis fans coming back for more.  

    Information about Lemon Cake strain

    Origin Lemon Skunk, Cheese
    Plant type 20% Indica / 80% Sativa
    THC 17%-23%
    CBD 0.43% – 0.7%
    Effects Mood-elevation
    Relaxation
    Arousal
    Flavors Lemon meringue and cheesecake
    Adverse Reaction Dry eyes, thirst, dizziness
    Flowering Time 63-70 days
    Yield (indoors) 2.3 oz/ft²
    Yield (outdoors) 21-28 oz/plant
    Grow difficulty Easy
    Lemon Cake Marijuana Plant

    Is Lemon Cake strain indica or sativa?

    Lemon Cake marijuana strain is a hybrid with an 80:20 sativa to indica ratio that works quickly to entice creative thought, focus, and introspection.

    This sativa-dominant hybrid is a testament to Heavyweight Seeds‘ reputation for making popular cannabis strains renowned for their flavor and fragrance. 

    Lemon Cake weed captures you with its aroma, satisfies you with its taste, and rewards you with its high. 

    Looking for marijuana seed deals? Subscribe to our seed deals to gain access to weekly deals on marijuana seeds!

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    Lemon Cake strain genetics 

    The growing popularity of this strain is certainly not unfounded. 

    Lemon Cake strain genetics is nothing short of legendary, handed down from industry heavyweights: 

    Lemon Skunk and the infamous Cheese.

    The sativa-dominant Lemon Skunk strain earned its reputation as one of the top strains in the world in 2009, rocking a 22% THC level and effortless growability. 

    And what stoner hasn’t the one and only Cheese strain blessed? This indica-dominant Afghani/Skunk #1 offspring makes the most of its modest 14% THC, proving a little goes a long way. 

    This skunk/kush combination has caught the attention of smokers and growers alike, with Lemon Cake strain reviews loaded with praise. 

    This global fan base is a sure sign  Lemon Cake is following in the family’s footsteps. 

    Cheese Marijuana Strain

    Buy Cheese Feminized Seeds

    • 60% Indica 40% Sativa
    • THC levels up to 14%
    • Great for indoors and warm climates
    • Strong smelling stress reliever

    Lemon Cake strain grow info 

    Lemon Cake weed strain has become quite sought after for its relatively easy-to-grow nature and generous yields. It prefers warm, semi-humid climates and is naturally hardy with fair resistance to mold and disease

    It requires far less attention than many finicky strains, but you must maintain adequate air flow and temperatures and practice trimming

    Lemon Cake plants grow 2.5ft to 4.6ft indoors and produce mossy green trees with a subtle purple hue and dense resin frosted nuggets, lending to the “cake” characteristics that make up its name. 

    The plants will need support to carry the weight of their large, dense colas. The grow produces a pungent aroma, so prepare your grow room with exhaust fans if you intend to keep a low profile. 

    Download my free marijuana grow guide and start growing Lemon Cake strain.

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    • Discover secrets to Big Yields
    • Avoid common grow mistakes

    Growing Lemon cake strain outdoors 

    Lemon Cake strain thrives outdoors in hot and semi-humid climates. These plants grow quite large (4ft-6ft tall), so you’ll need to prepare enough space for them to stretch out. 

    With the right conditions, techniques, and some TLC, you’ll be enjoying the THC of your harvest soon enough. 

    You can expect to harvest around mid-October in the Northern hemisphere or mid-April in the Southern hemisphere. 

    Lemon cake cannabis plant flowering
    Lemon cake strain flowering

    Lemon Cake strain flowering time 

    The rewards of a harvest are often a reflection of cultivation care, so be kind to your Lemon Cake plants, and they’ll be kind to you. 

    Indoor growers can anticipate a 63-70 day flowering period, but Lemon Cake strain info suggests you can achieve a shorter flowering time of 55-63 days with the right techniques.

    Lemon Cake strain yield

    Lemon Cake strain is popular amongst growers for being a vigorous, high-yielding plant regardless of cultivation skill. 

    Indoor growers harvest, on average, 21-24 ounces per square meter (up to 2.3 ounces per square foot). You can expect a whopping 21-28 ounces per plant outdoors.  

    Lemon cake cannabis plant
    Lemon cake plant

    Lemon Cake strain effects 

    Many have wondered if Lemon Cake strain is a sativa or indica. Although it’s a hybrid, the sativa qualities shine most in the Lemon Cake strain effects. 

    You’ll quickly experience an exciting buzz with a cerebral high, sparking creativity, imagination, and a wave of energy.

    You’ll love its mood-elevating charm, which spurs conversation, relaxation, and possibly arousal. 

    Like most sativa-based strains, Lemon Cake marijuana strain commonly relieves discomfort associated with various ailments, like persistent pain, muscle spasms, and inflammation. 

    Lemon cake strain is also effective against stress, anxiety, fatigue, and depression, as well as appetite loss

    You may feel elevated anxiety or paranoia if you don’t consume in moderation. You can expect a typical case of dry eyes and thirst (and maybe some dizziness).  

    Lemon cake marijuana flavor
    Lemon cake flavor

    Flavors & smell 

    The decadent flavors of Lemon Cake are reminiscent of Sunday afternoon desserts like lemon meringue and cheesecake, with a strong musky cheese overtone that’s impossible to miss. 

    The citrus pine aroma is thick and skunky, with a spiciness that bursts out once you crush the buds.  

    Limonene, one of the leading terpenes, contributes to the citrus flavor of Lemon cake. 

    This natural anti-inflammatory also speeds up our body’s terpene absorption, helping us gain more from them sooner. 

    Other terpenes include Myrcene, Caryophyllene, and Alpha-Pinene. 

    FAQs about Lemon Cake strain

    How long does a lemon cake high last?

    The Lemon Cake high lasts a few hours, but the exact length varies from person to person due to THC tolerance, consumption method, and other factors. Your body absorbs the THC differently with edibles versus vaping in a Lemon Cake cart.

    What’s the difference between Lemon Kush, Lemon Cake, and Lemon Cake OG?

    Lemon Cake OG is a strain that crosses Lemon OG with Jesus OG, but some also use the name to describe Lemon Cake. Lemon Kush has a lineage of Afghani indica, South American sativa, and Lemon G mixed with Master Kush. As for Lemon Cake Kush, that’s not an official strain. But who knows – maybe a Lemon Cake Kush strain is in the making.

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    Robert Bergman

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  • Moonbow strain

    Moonbow strain

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    Moonbow strain is one of the more recent creations from Archive Seed Bank, limiting Moonbow weed strain info to a degree. 

    Indica / Sativa Indoor yield Outdoor yield Flowering period
    50% – 50% 1.60 oz/ft² 10 – 15 Oz/plant 8-9 weeks

    However, we know it combines Zkittles with Do-Si-Dos into a strain that delivers all the pleasantries we expect from professionally engineered hybrid strains. 

    It is also called Moonbow #112 since it is the 112th phenotype from the Moonbow family. 

    Learn more about the Moonbow cannabis strain

    The Moonbow cannabis strain is a perfectly balanced hybrid, dispensing an even 50/50 mix of indica and sativa that evokes an uplifting yet calming and relaxed high. 

    A high point for many who come into contact with this strain is its fragrant aroma and mouth-watering flavors that will make you come back for more.

    Moonbow weed strain properties:

    Origin Zkittles, Do-Si-Dos
    Plant type 50% Indica / 50% Sativa
    THC 18%-20%
    CBD 0%
    Effects Uplift
    Relaxation
    Flavors Sweet berry, citrus, spice
    Adverse Reaction Cottonmouth, red eyes
    Flowering Time 8-9 weeks
    Yield (indoors) 1.60 oz/ft²
    Yield (outdoors) 10 – 15 Oz/plant
    Grow difficulty Moderate

    Moonbow strain yield

    The information regarding Moonbow strain yields and flowering times are still up for debate, but if its parent strains are anything to go by, expect yields around 1.60 oz per square foot. 

    This would, of course, be nothing more than an assumed estimate. 

    Like most new strains, the Moonbow pot strain price will likely peak during initial popularity but eventually stabilize as more growers acquire a Moonbow seed or two of their own. 

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    Moonbow THC content

    Moonbow CBD content may not be as high as some other strains; however, the THC content is high enough to take you to the moon. 

    Fortunately, it’s not so powerful that you’ll go intergalactic. 

    With a cool 18-20% THC average, the Moonbow marijuana strain is potent enough to give the more adept smokers a satisfying high while still being suitable for newbies to cut their teeth on something a little tougher. 

    Zkittlez Marijuana Strain

    Buy Zkittlez Feminized seeds

    • 70% Indica 30% Sativa
    • THC levels up to 23%
    • Easy growing strain
    • A great strain for relaxation

    Moonbow effects

    The name should already indicate the type of effects Moonbow cannabis strain may provide. 

    This nighttime strain gives rise to a blissful full body high that caresses your muscles and your mind, easing tension and stress. 

    Moonbow effects are long-lasting, uplifting, and accompanied by a subtle vibrational hum that permeates your limbs, lulling you into a blissful state of relaxation, if not deep sleep.

    One of the best things in life is to slow down and smell the roses, and Moonbow can help you do that. 

    The calming effects of Moonbow #112 strain have made it an admired choice for insomnia and anxiety. 

    It’s also useful for pain, nausea, and headaches brought on by chronic stress and fatigue.

    fragrance 

    Moonbow strain fragrance 

    On the “Subtle-to-Stank” scale, Moonbow strain scores a solid  “Daaayyymn,” with its intense sticky nuggets providing little to no discretion in the scent department.  

    If you intend to keep it low-key, good luck. The sheer dankness of this grape-scented candy strain is something to admire and will most certainly have your friends asking for a hit. 

    It’s a decadent combination of fruity sweet and sour aromas, earthy undertones, and some skunkiness for good measure.  

    Moonbow strain flavors

    Moonbow is sought after for its rich flavor. It is a buffet of tastes that deepen with every hit. Initially, a sweet berry with deep floral notes is the most prominent flavor. 

    It entices your palate and prepares you for the approaching buzz. On the exhale, the strong elements of citrus and spice are most noticeable. 

    If I had a full jar of Moonbow strain near me, I assure you, it wouldn’t be that way for long. 

    Download my free marijuana grow guide and start growing Moonbow weed strain.

    marijuana grow bible

    Moonbow weed strain negative reactions

    As with many mid-to-high level strains, expect a few unwanted reactions. They’re pretty much unavoidable but bearable. 

    That doesn’t mean you can’t do something about them.  

    Moonbow marijuana strain is likely to make you quite thirsty, so stock up on some refreshments to curb that cottonmouth and maybe grab some eye drops in case your eyes redden up. 

    You may also want to consider some snacks, as the monster munchies are a very real possibility.  

    Growing Moonbow cannabis strain

    Growing Moonbow weed strain

    As mentioned earlier, the information on growing Moonbow pot strain is still unconfirmed; however, looking at its genetic predecessors may indicate what potential Moonbow growers can expect. 

    As with many hybrids, especially those indica leaning, they prefer warm, sunny, and semi-humid climates with adequate ventilation to avoid any mildew issues. 

    Based on its parents, it may grow to medium height, producing bushy plants displaying average growing difficulty

    Generally, appropriate care and attention will bring out the best in your plants, regardless of what strain you intend to grow. 

    In the meantime, refer to our grow guide for the best tips on getting your crop thriving.      

    cannabis strain flowering
    Moonbow weed strain flowering

    Moonbow strain flowering time

    The average flowering time of the Zkittlez strain is around 8-9 weeks, with an outdoor harvest expected in early October; we assume that Moonbow #112 strain schedules are similar. 

    As more growers get their hands on Moonbow marijuana seeds, we’ll learn more – but only when we share.. 

    So drop us a Moonbow marijuana strain review and let us know what your experience was growing this particular phenotype.  

    Do-si-dos marijuana strain

    Buy Do-si-dos seeds

    • 70% Indica 30% Sativa
    • THC levels up to 30%
    • Easy growing inside and outdoors
    • You feel both relaxed and euphoric

    Moonbow strain genetics

    Both the predecessors of Moonbow strain genetics, Zkittlez strain and Do-Si-Dos, have established a rapport for divine flavor and cemented their place in cannabis legacy for their euphoric effects and all-around smokable appeal. 

    Do-Si-Dos is a potent hybrid strain stemming from the OG Kush family with intense creative-inducing effects and an unmistakable fragrance. 

    Combine that with Zkittlez, the fruity-flavored offspring of the Grape Ape family, and you are bound to have a potent concoction of flavor and potency that’ll have you coming back for more.

    FAQs about the Moonbow

    Is Moonbow indica or sativa?

    Moonbow weed strain is a 50/50 balanced hybrid, meaning it’s half sativa and half indica. Its effects are also evenly balanced, having a robust indica body high while maintaining the upbeat mental buzz that sativa is known for.

    Where can you buy the Moonbow strain?

    Many dispensaries sell  Moonbow #112; it is most popular in  Oregon and California. Moonbow seeds are also available with some searching. 

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  • Bubba Fett strain

    Bubba Fett strain

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    There’s no need to venture to galaxies far, far away to find strains that are out of this world, thanks to Colorado-based cultivator Green Dream Cannabis

    Indica / Sativa Indoor yield Outdoor yield Flowering period
    70% – 30% 0.5-1.3 oz/ft² 20 oz/plant 42-56 days

    Their Bubba Fett strain is a heavily indica-dominant (70%-30%) hybrid with a potency of up to 29% THC.  It’s been racking up a body count ever since day one. 

    Learn more about the Bubba Fett cannabis strain

    Bubba Fett weed strain (not to be confused with the Boba Fett strain) is a crossbreed of Pre-98 Bubba Kush and Stardawg that delivers an overwhelmingly relaxed high. 

    Along with its potent indica effects, this strain can contain a relatively high CBD content, making it a fan favorite for those turning to cannabis for therapeutic reasons.  

    Information about Bubba Fett strain

    Origin Stardawg, Pre-98 Bubba
    Plant type 70% Indica / 30% Sativa
    THC 29%
    CBD 0.2% – 0.48%
    Effects Happiness
    Calmness
    Relaxation
    Flavors Tropical fruit, subtle citrus, sweet berries, woody spice
    Adverse Reaction Couch lock, dry eyes, and thirst
    Flowering Time 42-56 days
    Yield (indoors) 0.5-1.3 oz/ft²
    Yield (outdoors) 20 oz/plant
    Grow difficulty Easy

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    Is the Bubba Fett strain indica or sativa?

    If you have any doubts, the steamrolling effects of smoking this bud will quickly quell any speculation around the possible Bubba Fett strain sativa or indica dominance

    With a 70% indica to 30% sativa ratio, you should have a clear INDICAtion that you will have a calm, early night in. 

    Bubba Fett strain genetics

    Bubba Fett strain genetics are remarkable considering its parent strains are polar opposite dominant hybrids

    On the one side, you have Pre98 Bubba Kush with an 85% to 15% Indica dominance and a 20% THC average. 

    Hindu Kush Strain

    Buy Hindu Kush seeds

    • 100% indica strain
    • THC levels up to 18%
    • Great for dry and warm climates
    • Nice subtle relaxing and calming effect

    This couch-locking strain stems from the legendary Hindu Kush and has a rich, earthy flavor with hints of coffee. 

    On the other side of the Bubba Fett strain family tree is Stardawg. It’s a heavily sativa dominant strain that delivers fast, hard-hitting head-highs that spur creativity and energy. 

    Stardawg (aka Star Dog) is one of the most potent strains from the Chemdawg #4 lineage after being bred with the Tres Dawg strain.

    Bubba Fett strain grow info

    If you’ve happened to get yourself some Bubba Fett strain seeds, and you’re unsure about what to expect from your grow, then we’re happy to put your mind at ease. 

    Thankfully the Bubba Fett weed strain is easy to grow with a relatively short flowering time. 

    It produces short plants of around 30”, making it the ideal candidate for indoor growers who don’t have an abundance of space. 

    Growing Bubba Fett cannabis strain outdoors
    Growing Bubba Fett

    Growing Bubba Fett strain outdoors

    Outdoor cultivators that want to attempt planting Bubba Fett strain seeds shouldn’t expect massive plants with overwhelming yields

    However, if your crop is cared for and cultivated in a moderately warm climate, you can expect a satisfying yield.  

    Bubba Fett strain flowering time

    The beauty of growing the Bubba Fett strain is its pleasantly short flowering time. 

    To get the best results, utilize 12 hours of light every 24 hours throughout the vegetative stage (the first 42-56 days). 

    Change to an 18-hour per 24-hour light cycle when your plants enter the flowering phase.

    Growing Bubba Fett strain outdoors
    Growing Bubba Fett

    Bubba Fett strain yield

    A general consensus across many Bubba Fett strain reviews is that, although it may not be the largest yield-producing strain, it compensates by being powerful and flavorful. 

    It’s a super strain for indoor growers that want to grow enough for themselves, yielding on average 0.5-1.3oz per square foot. 

    The Bubba Fett strain info for outdoor growers is scarce; however, growers can yield up to 20 ounces per plant.

    Download my free marijuana grow guide and start growing Bubba Fett strain.

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    • Grow with my Quick Start Guide
    • Discover secrets to Big Yields
    • Avoid common grow mistakes

    Bubba Fett strain effects

    Getting your ass intergalactically kicked by a strain with a name that sounds like a hillbilly rapper is not how most would want to spend their evening, so take it easy when smoking the Bubba Fett strain. 

    Calm-minded and physically sedated are the states one would convey when describing the Bubba Fett strain effects. 

    Anxious thoughts and tense muscles fade as the waves of relaxing effects flow through your body, easing you into your evening. 

    The strain’s popularity is rising, especially for chronic pain, inflammation, spasms, and fatigue. 

    Many have also found that Bubba Fett strain helps with stress, depression, insomnia, and appetite (expect maddening munchies). 

    Couch lock, dry eyes, and thirst are normal when smoking this strain, so plan accordingly.

    A woman smelling the flavor of Bubba Fett strain
    Bubba Fett strain flavor

    Flavors & smell

    The nuggets of the Bubba Fett strain emit a dense pungency that’s impossible to explain away, so if you don’t intend to share (shame on you), keep that jar sealed tight. 

    Its aroma is thick and dank, with hints of tropical fruit and earthy elements that peek through a blanket of skunkiness. 

    Its flavor accentuates the tropical tones with subtle citrus and sweet berries, layered with woody spice and herbs, and the presence of diesel on the exhale.

    FAQs about Bubba Fett strain

    How strong is the Bubba Fett strain?

    The potency can vary from grower to grower. Some people have reported THC contents ranging from 15-29%. The average seems to be in the mid-twenties, so you can rest assured that you will get baked. 

    Are Bubba Fett and Boba Fett the same strain?

    No. Bubba Fett strain originates from Stardawg X Pre98 Bubba Kush. Boba Fett strain is the result of Snake Eyes strain crossed with Lemon Haze Bubblegum. 

    Is Bubba Fett strain suitable for indoor growing?

    Yes, Bubba Fett weed strain is not only suitable for indoor growing, but it’s almost preferred. This short strain thrives within moderately warm temperatures, which are best maintained with indoor set-ups.

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  • Ticker: Weed judges wanted for Cannabis Cup; Mt. Washington Observatory names new director  – The Cannabist

    Ticker: Weed judges wanted for Cannabis Cup; Mt. Washington Observatory names new director  – The Cannabist

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    Cannabis connoisseurs living in Bay State are invited to flex their taste buds in a competition to choose the People’s Choice awards in the state’s edition of High Times’ Cannabis Cup.

    The glossy schwag mag is looking for up to 2,200 resinated residents to sample the best of the state’s locally grown bud and edibles for flavor and effect.

    Mark Kazinec, High Times director of events, said sampling kits will be available at 30 dispensaries around the state beginning Sept. 24. Judges will be tasked to assess the buzz on products across 13 categories including best indica, sativa and hybrid flower; gummies, chocolates, drinks, concentrates and more.

    Read the rest of this story on BostonHerald.com.

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  • Colorado’s medical marijuana sales hit lowest point since legalization – The Cannabist

    Colorado’s medical marijuana sales hit lowest point since legalization – The Cannabist

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    Colorado’s medical marijuana sales fell to their lowest point since retail sales began — the latest signal that the state’s once-robust industry is facing headwinds as others crowd the U.S. market and new regulations take hold.

    In July, the state’s marijuana sales for both recreational and medical were shy of  $154 million, according to Colorado Department of Revenue figures, down from nearly $203 million a year earlier. Sales for the calendar year have passed the $1 billion mark.

    July’s medical marijuana sales reached a little more than $18 million – the lowest monthly number since January 2014, when retail sales were legalized in the state. Recreational marijuana sales fared better at more than $135 million – down from $168 million a year earlier, but higher than the numbers in April, May and June.

    Read the rest of this story on DenverPost.com.

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    The Cannabist Network

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  • Researchers Studying Psilocybin as Treatment for Obesity

    Researchers Studying Psilocybin as Treatment for Obesity

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    Building on the growing evidence that psilocybin has the potential to treat a host of serious mental health conditions, researchers are now studying the effects that the active component in magic mushrooms might have on obesity.

    Previous research into psilocybin and other psychedelics has repeatedly shown that the drugs may be an effective treatment for mental health conditions including depression, anxiety, PTSD, and addiction. Additionally, a correlational study published last year determined that those who reported having tried a classic psychedelic drug at least once during their lifetime had a significantly lower chance of being overweight or obese.

    In a recent study, scientists affiliated with the University of Copenhagen in Denmark conducted an experiment with mice to investigate the potential of psilocybin to reduce food cravings. To conduct the study, the researchers used mouse models of genetic obesity, diet-induced obesity and binge-eating disorder to investigate the effect of psilocybin on body weight and food intake.

    Initial results showed that a single high dose of psilocybin or a daily microdosing did not lead to reduced body weight or less food intake among obese mice treated with the drug. Although they did not find evidence to support the hypothesis, they were encouraged by the study and urged further research.

    “We were surprised to see that psilocybin did not have at least a subtle direct effect on food intake and/or body weight in genetic and diet-induced models of obesity and overeating,” study author Christoffer Clemmensen, an associate professor at the University of Copenhagen, told PsyPost. “Although we failed to discover major effects of psilocybin on mouse energy metabolism and behaviors associated with eating, we believe that there are nuances of the mode of action of psychedelics that cannot be appropriately captured in rodent models. Importantly, psilocybin was safe and had no adverse effects on the physiological parameters we tested in mice.”

    Obesity is Common and Costly in the U.S.

    Obesity is one the most pressing health problems in the United States, affecting nearly 42% of adults from 2017 to 2020, according to data from the Centers for Disease Control and Prevention. The obesity prevalence was 39.8% among adults aged 20 to 39 years, 44.3% among adults aged 40 to 59 years, and 41.5% among adults aged 60 and older.

    Health conditions related to obesity include heart disease, stroke, type 2 diabetes and certain types of cancer, helping to make them among the leading causes of preventable, premature death. The annual estimated medical costs of obesity totaled approximately $173 billion in 2019, adding about $1,861 to the medical costs for each person with obesity.

    “Perhaps surprisingly, obesity is a rather treatment resistant disease that shares neuropathological similarities to mental disorders, such as addiction,” said Clemmensen.

    “Dysfunctions in homeostatic and reward circuitry can lead to ‘relapse’ in people with obesity, making it difficult to adhere to lifestyle and even drug interventions. Given that psychedelics are thought to enhance the plasticity of neural circuits, it may be that when combined with behavioural therapy, psychedelics might be powerful tools for ‘resetting’ long-held compulsive behaviors. Further, classic psychedelics act on the serotonergic system, and could have a direct effect on food intake by broad activation of serotonin (5-HT) receptors, emphasizing their potential benefits for obesity.”

    The researchers noted that despite their value to scientific research, mouse models are not a perfect substitute for human subjects and encouraged further study into the potential of psilocybin to affect food intake and weight.

    “The main caveat is translation,” Clemmensen said. “Although animal models in general have been invaluable for neuroscience and metabolism research they might be inappropriate for testing health benefits of psychedelics.”

    “I remain excited about this topic, psychedelics for treatment of obesity and eating disorders and I think we should start considering what sub-groups of patients could benefit from this drug class,” he added.

    The study, “Acute and long-term effects of psilocybin on energy balance and feeding behavior in mice,” was published last month by the peer-reviewed journal Translational Psychiatry.

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    A.J. Herrington

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  • What is NPK, why is it important and how does it affect your cannabis plant? | Crop King Seeds | Crop King Seeds

    What is NPK, why is it important and how does it affect your cannabis plant? | Crop King Seeds | Crop King Seeds

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    Cannabis cultivation can be traced back to 2800 B.C. In the intervening years, the popularity of marijuana has exploded and now growers are coming out of the woodwork, sometimes quite literally, to show off their growing skills.

    As cannabis continues to normalize and more states legalize the recreational cultivation of cannabis, newcomers are going to begin exploring the process to try and find their successful path.

    To find success as a grower, particularly in the cannabis industry, you are going to have to learn the key nutrients that can impact the health and vitality of your plant, as well as the total yield of its THC-producing buds.

    What Is NPK?

    Nitrogen (N), phosphorus (P), and potassium (K) are the vital micronutrients that your cannabis will need to satisfy its total growth potential. Paying attention to these micronutrients while addressing any deficiencies during the life cycle of your plant will go a long way toward a bountiful harvest with an exponential yield.

    There are plenty of different nutrients and environmental factors that go into growing a healthy marijuana plant, but we need to start with the core trio, your NPK.

    Let’s explore the NPK ratio, learn about symptoms pertaining to deficiencies, and explore how to better treat our plants for more bountiful harvests in the future.

    All About Nitrogen (N)

    As the primary micronutrient in the life cycle of your cannabis plant, it is important that appropriate levels of nitrogen are available throughout both the vegetative and flowering stages of the plant. This element is entirely pivotal throughout the lifecycle of the plant as nitrogen is important to the production of chlorophyll, a compound required for photosynthesis. 

    As the most common element in the earth’s atmosphere, nitrogen can be fed throughout the cycle of your plant via soil amendments and liquid nutritional amendments. By providing appropriate levels of nitrogen, your plants will be able to produce the genetic coding required to produce stems, leaves, branches, and roots.

    Signs of Nitrogen Deficiency

    While nitrogen is an easy micronutrient to incorporate into your growing cycles, deficiencies can still happen and they can cause some chaos. To better catch potential nitrogen issues while cultivating your cannabis plant, look for the following signs and symptoms.

    • Older leaves begin to yellow, spreading to the rest of the plant.
    • Leaves and stems may begin to turn purple.
    • Leaves can begin to wilt, beginning at the tips.

    All About Phosphorus (P)

    Integral during the flowering stage of your cannabis plant’s growth, phosphorus is an important nutrient that helps to fortify the entire structure of the plant. An adequate level of phosphorus will help to fuel the plant’s structure while improving the health of its roots and, ultimately, the flowering buds.

    Phosphorus is also relied upon during the termination of your cannabis plant as it immediately and directly impacts the distribution of energy throughout the rest of the plant. A lack of phosphorus can make for a slew of health-related issues with your plant, so let’s briefly learn what to look out for during the cultivation process.

    Signs of Phosphorus Deficiency

    When there is a lack of available phosphorus for your plant, the symptoms, and signs of fallout will be easily detectable. As phosphorus is required throughout the lifespan of your plant, from germination to harvest, pay close attention to signs of nutritional deficiency as they can have far-ranging effects during your grow.

    • Slow-growing leaves begin to turn blue or green with brown spots.
    • Stems will begin to turn a purple color.
    • Leaves may begin curling down and toward the ground.
    • Your plant does not enter the flowering stage.

    All About Potassium (K)

    The hidden workhorse in your NPK ratio is potassium. Acting as an auxiliary nutrient, Potassium works to regulate the systems required for a healthy and thorough growing process. Potassium can be thanked for ensuring the firmness of stems as well as the adequate production of ADP for the storage of energy. In addition to these factors, potassium also plays a major role in moisture evaporation.

    Crucial from the beginning of flowering to the end of your harvest, potassium is used to control flowering bud formation while keeping cell pressure steady to protect the plant from stress. Potassium deficits can become particularly problematic while manifesting in a few different ways.

    Signs of Potassium Deficiency

    A lack of potassium can manifest as a major issue throughout the lifespan of your cannabis. Incredibly important in the flowering stage, a lack of potassium can lead to a harvest that is weak, limited, and altogether lacking in appeal.

    • Weak and low-energy plants
    • Plants are more vulnerable to disease and pests.
    • Leaves begin to showcase yellow edges.
    • The plant is unable to regulate oxygen, water, and CO2 exchange.
    • Weak stems and thin stretched branches.

    In addition to potassium deficiencies, an overload of potassium can also lead to issues during the flowering stage. Too much potassium can cause issues during the uptake process, leading to a plant that is improperly fed and poorly equipped for the final stages of flowering.

    Take Control of Your NPK

    Cannabis plants require a diverse array of micro and macronutrients to thrive under the guidance of a grower. Use our outline above to better understand the different functions each micronutrient serves while better learning how to implement these improvements in your own garden.

    When making adjustments to your NPK, slow and small changes will lead to the best results. A nutrient monitor is an ideal tool to keep track of your NPK levels to make better changes to your plant in the future.

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    colabarmy

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  • The Weedmaps’ 420-friendly travel guide to San Francisco

    The Weedmaps’ 420-friendly travel guide to San Francisco

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    Boom or bust, San Francisco remains an iconic international destination. The majestic Golden Gate Bridge symbolizes the city’s status as the home of many unique attractions, as well as a global hub for industry, commerce, technology, and culture.

    Where else can you have Irish coffee in Fisherman’s Wharf, dim sum in Chinatown, Mexican food in the Mission District, and fresh, farm-to-table five-star dining in the Financial District, followed by a nightcap in North Beach — all in one day?

    Combine all that with the counterculture vibe, cultural diversity, coastal climate, and colorful history, and San Francisco is a must-see for most tourists from near or far. Travel and tourism operator Club Med declared San Francisco the fourth “happiest” travel destination in America for 2022. Add a bit of cannabis, and it could be your number one by far.

    Travel and cannabis in San Francisco

    Northern California’s agricultural bounty has always been a rich resource for the city’s elevated aesthetic, with everything to offer from regional farms to vast vineyards. So, it’s only natural that legal cannabis is the latest connoisseur experience to bring added allure to Bay Area vacations.

    After all, since the social revolution of the 1960s, some of the world’s best cannabis has been grown in the Emerald Triangle, just three hours north of the city.

    “We’ve experienced wine consumers who, when they come to California, have the desire to take a tour through Napa or Sonoma County with us. We’re starting to see an uptick in those consumers that want to experience California cannabis, really in California. It’s one experience that’s very California, and it’s very San Francisco,” said Victor Pinho, founder of Emerald Farm Tours.

    Here are some 420-friendly accommodations, destinations, and activities to try in San Francisco.

    420-friendly hotels in San Francisco

    Cannabis-friendly accommodations in San Francisco (and California) are largely short-term rentals that can be found online at booking platforms like HiBnB.com, BudandBreakfast.com, and Inndica.com. Vendors on conventional booking sites, like Airbnb, that welcome cannabis tourists will typically denote that they’re “420-friendly.”

    Listings can be sparse, even in big, legal cities like San Francisco, as regulations and permitting for cannabis-friendly accommodations are just starting to be developed by local policymakers. The presence of nearby consumption lounges may alleviate some of the necessity for cannabis-friendly accommodations since they provide a permitted, legal space for public consumption.

    Noe’s Nest Hideaway

    Accommodations in San Francisco include Noe’s Nest Hideaway, centrally located in the city’s desirable Noe Valley neighborhood, in a stately Victorian home among rows of old Vics and Edwardian architecture. The bed-and-breakfast allows outdoor consumption in a private backyard.

    The Purple Room

    In Duboce Triangle, adjacent to the better-known Castro District, there are accommodations at The Purple Room. This shared townhouse is conveniently located directly over the Flore Dispensary for what would be a most unique cannabis-friendly experience with WiFi, a big-screen TV, a full kitchen, board games, and a washer/dryer. Consumption is allowed on a private outdoor balcony and porch.

    Hotel Kabuki

    Conventional hotel accommodations that are also 420-friendly are hard to come by. Hotels that are rumored online to be cannabis-friendly often will not list any indication of being so on their websites or elsewhere. That’s the case with San Francisco’s Hotel Kabuki, located at 1625 Post Street. Previously a Joie de Vivre Hospitality property, the boutique hotel is now operated by Hyatt. Located near the Fillmore District, the Kabuki is hip, retro rock & roll-themed, and pet-friendly. Though cannabis consumption is not mentioned anywhere on the hotel’s official website, the travel platform Trivago Magazine lists Hotel Kabuki as one of “eight great 420-friendly hotels in California” thanks to its large outdoor garden.

    420-friendly destinations in San Francisco

    If you’re looking to do more with your West Coast cannabis than smoke a little weed and walk around the city, then check out these activities made for tourists and locals alike.

    Emerald Farm Tours

    San Francisco-based tour company, Emerald Farm Tours, offers visitors several options for enjoying cannabis while sightseeing in some of the city’s most popular neighborhoods.

    In US cities with access to recreational cannabis, where rules and regulations for public consumption are evolving, cannabis touring companies like Emerald Farms are becoming more popular. They typically feature cross-promotions with local retailers and lounges, as well as cannabis-friendly venues and events.

    3-hour bus tour

    “If you come to San Francisco and you really want to experience the city with cannabis, then take the $195 3-hour bus tour. That’s the most popular cannabis tour, which takes you to three dispensary lounges, some sightseeing, and pairings at a winery, where you get to do wine-tasting,” Pinho said.

    Book the Cannabis bus tour

    All-day tour with wine and weed

    “If you want to delve deeper into it, then I recommend our whole day tour that takes you to the southern corner of the Emerald Triangle, to Anderson Valley, where we take you to a beautiful cannabis farm, and you can walk around and take pictures,” he described.

    Book the Wine, Wilderness, and Weed Tour

    Walking the Wharf Tour

    “The Wharf Tour is a little lighter,” Pinho added. “It’s a walking tour — we start in Fisherman’s Wharf, and it’s not a far walk. We cover about a half-mile in two hours, so it’s easy to do. Guests get to visit two dispensaries, hear about the sights, and it’s good if you just want to get your feet wet and experience cannabis for a couple of hours while you’re in the city.”

    Book the Fisherman’s Wharf — Walking Tour

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    Visit a Bay Area dispensary

    Dispensaries can be found throughout all of the city’s unique neighborhoods.

    Seaweed SF and Stiiizy’s

    Aptly named Seaweed SF in Fisherman’s Wharf is a cable car ride away from Stiiizy’s branded flagship store in Union Square.

    Visit Seaweed SF

    Visit Stiiizy’s Union Square

    The Apothecarium

    The Apothecarium, founded in 2011, has locations in The Castro and SOMA district and offers online and phone consultations.

    Visit The Apothecarium

    Vapor Room

    Originally a medical cannabis dispensary during the Prop 215 days, The Vapor Room was one of the first consumption lounges in California. It was shut down by the feds in 2012 and is now back, located in the South of Market area.

    Visit Vapor Room

    Bloom Room

    Bloom Room in San Francisco is located near Union Square, Mint Plaza, and the Westfield Shopping Center.

    Visit Bloom Room

    Berner’s on Haight

    In the famously psychedelic Haight-Ashbury neighborhood, visitors can find Berner’s on Haight, the dispensary owned by hometown rapper and cannabis entrepreneur Berner.

    The Cookies cannabis brand that Berner co-founded is well known for its proprietary strains and bright blue painted storefronts. New Age hippies and day-trippers can visit the dispensary and peruse the Haight’s vintage vinyl and clothing stores, as well as local landmarks like Buena Vista Park and the old Victorian houses once occupied by the Grateful Dead, Jimi Hendrix, and Janis Joplin.

    Visit Berner’s on Haight

    Toke up at Moe Greens consumption lounge

    Moe Greens is located at 1276 Market Street and is open daily. Established in 2019, the store features a consumption lounge where guests can purchase products to enjoy onsite, in addition to offering its regular retail and delivery options.

    Wood-framed windows and exposed brick walls lined with green-upholstered banquettes and tables give the lounge’s interior a speakeasy-type feel. “We built it out just like a normal bar at a restaurant,” said Sean York, marketing director at Moe Greens. “You can pull up on Friday, and it gets pretty packed. People are talking, like at a normal bar. It’s a very popular thing because it’s unique, not only in San Francisco but just unique in general.”

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    A special feature at Moe Greens is a dab bar, where customers can consume a variety of cannabis concentrates using state-of-the-art dabbing equipment like the Puffco Peak or Zenco Flow. Specially trained dab bartenders help consumers choose concentrates and assist with equipment usage.

    “You know, we have the Orpheum [Theater] and a lot of other cool things to see around here. A lot of people come in before the symphony or concerts at the Bill Graham [Civic Auditorium], and they’ll do a dab or some flower and enjoy the weekend.”

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    Like most lounges, Moe Green’s offers a full roster of events for guests that includes live music, comedy nights, drag brunches, and open mics. York said they’ve hosted a lot of different activities and also cater to crowds of visitors that come to San Francisco for big sports and entertainment events. Maybe no surprise, with such close proximity to the world’s largest tech corporations, York said that the lounge’s most popular event is their gaming and dabs night.

    Celebrate 4/20 at Hippy Hill

    As events go, there is none bigger for cannabis enthusiasts than April 20. The unofficial stoner holiday was actually born across the bay from San Francisco, in the neighboring town of San Rafael. As the urban legend goes, a group of high schoolers in the 1970s would meet at 4:20 pm for afternoon smoke sessions, and the time evolved into a secret code for their sesh activities.

    For tourists with cannabis at the top of their bucket lists, the 4/20 Festival at Hippy Hill held in Golden Gate Park is an unrivaled opportunity to experience the ultimate social cannabis experience. Prior to the pandemic in 2019, 19,000 attended the celebration on Hippy Hill, overlooking Robin Williams Meadow.

    After a pandemic hiatus, the festival returned in 2022 with the first sales of legal cannabis products happening at the event.

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    Joanne Cachapero

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  • 420-Friendly Travel Guide: Los Angeles

    420-Friendly Travel Guide: Los Angeles

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    There are few destinations that offer such a diversity of experiences as Los Angeles, California. It’s a little overwhelming with all the things you can do or see in a week in LA in general, but now, consuming legal cannabis is one activity that can be added to your vacation itinerary — for both weed connoisseurs and the more beginner cannabis-curious.

    And of course, LA is going to do legal cannabis and cannabis-friendly attractions as only LA can, precisely because it can.

    Find Los Angeles dispensaries and more on the Weedmaps app

    Travel and cannabis in LA

    Since recreational cannabis was legalized in California in 2016, local cannabis entrepreneurs have been scheming to become a sort of “Amsterdam of the West,” offering visitors from around the world the opportunity to access cannabis in legal, often very high-end retail settings.

    In 2022, LA expects to welcome more than 46 million international tourists. The top five global markets for Los Angeles include visitors from Mexico, China, Canada, Australia, and the UK (in that order).

    Traveling consumers often have difficulty finding cannabis-friendly hotel accommodations, even in legal locations like Los Angeles. However, that may change if cannabis tourism becomes more accepted. Check out short-term rental sites like Inndica and BudandBreakfast, which will help you locate “420-friendly” accommodations in legal states to get your LA trip started on the right foot.

    420-friendly destinations in LA

    Here are some 420-friendly destinations and activities to try in Los Angeles.

    Weed Bus LA Tours

    At Weed Bus LA, visitors can book cannabis-friendly bus tours, as well as activities hosted at various facilities in Hollywood and downtown LA. Rollin Budz, the owner of Weed Bus LA, said that their most popular activity is Stoner Paint Night held at a DTLA studio. The evening includes a two-hour paint sesh with instruction, a $20 cannabis voucher, and paint supplies. Participants may bring their own cannabis or adult beverages if they wish.

    Planning ahead for the autumn months in LA, Budz said that the Stoner Paint Night will include psychedelic pumpkin paintings for September and October. Two upcoming classes — Blunts & Burritos and Blunts & Sushi — will also be added to the roster as soon as Budz can find a professional blunt roller to help lead the classes.

    Aside from painting, Weed Bus LA has three weed tours to choose from:

    • Grow & Lounge Tour: The bus transports guests to two local indoor grow facilities where they can walk through, observe cannabis plants being cultivated, ask questions of a master grower, and receive a $20 goody bag of products. The tour can be scheduled in multiple languages, though guests with special requests should call ahead to book. Private tours can accommodate special events, like birthdays and bachelor/ette parties.
    • Hollyweed & Wine Tour: Guests go on a guided walk down the Hollywood Walk of Fame to see the stars of weed icons Snoop Dogg, Bob Marley, and local LA rappers Cypress Hill. The bus winds through West Hollywood to Beverly Hills and includes a stop at a local winery with complimentary tasting, as well as weed and wine pairings.
    • Dispensary Crawl Tour: Also known as the “Friday” tour, this three-hour guided tour takes guests on a trip to historic South LA and by movie locations from 1995 stoner comedy Friday, including characters Mrs. Parker and Craig’s house, which are fun backdrops for Instagram-able photos. Guests also visit Nipsey Hustle Square, a Kobe Bryant memorial mural, and Crypto.com (formerly known as Staples Center), in the heart of DTLA. A $20 cannabis voucher and penny pre-roll are included.

    For visitors that would like to have their own private sesh or try new methods of consumption, Weed Bus LA — like many tour companies in other legal destinations — rents out premium cannabis gear, including gravity bongs and dab rigs.

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    Celebrity-owned or frequented dispensaries

    Celebrity culture lives large in Los Angeles, so, it will be no surprise that several local dispensaries are owned by well-known stars from stage and screen. Some dispensaries are rock stars in their own right, featuring famous OG cannabis strains, and are frequented by famous cannabis enthusiasts.

    Dr. Greenthumb

    It doesn’t get more OG than legendary rapper and LA native B-Real, who owns dispensary chain Dr. Greenthumbs. The retail store, conveniently located near Los Angeles International Airport, can be the first stop on any cannabis tourist’s trip into town.

    Eight Dr. Greenthumbs stores are located throughout Southern California, with one San Francisco location.

    Visit Dr. Greenthumb DTLA

    Cookies

    Head north to trendy Melrose Avenue to cannabis chain Cookies‘ first LA storefront. Founded by rapper and cannabis entrepreneur Berner, Cookies has become an internationally recognized cannabis brand, with storefronts in Israel, Europe, and several US states.

    Berner recently became the first cannabis industry executive to be pictured on the cover of Forbes Magazine’s print edition. The brand’s flagship bright blue buildings can’t be missed, and visitors to Cookies will find legacy proprietary strains like Lemonchello, Cereal Milk, and Medellin, among others.

    Visit Cookies Melrose

    Sherbinski’s and Wonderbrett for celebrity sightings

    In the Fairfax District, which is home to sneakerhead stores and all things hypebeast, Sherbinski’s reputation was founded on award-winning Gelato strain genetics. The brand boasts a long list of celebrity clientele, including artists Wiz Khalifa, John Mayer, and Ty Dolla Sign, among others.

    Also in the Fairfax District, cannabis retailer Wonderbrett has been built on its reputation for developing top genetics, including its OG Kush strain. Loyal customers, like rappers Snoop Dogg, Eminem, Xzibit, and Dr. Dre, have been clients for 20 years — according to the company’s website.

    Visit Sherbinski’s

    Visit Wonderbrett

    Cannabis consumption lounges in West Hollywood

    The City of West Hollywood, tucked between DTLA and Beverly Hills, is on course to see more than a dozen consumption lounges roll out over the next two years. Local cannabis tourism organization Emerald Village‘s Executive Director Scott Schmidt said they are working with local government to set standards and policy for cannabis tourism that may become a model for other cities to follow.

    Since public consumption of cannabis is prohibited in California, except in permitted facilities and spaces, Schmidt said that visitors should take advantage of the safest, most secure option for social consumption, as well as unique entertainment and activities offered by the lounges.

    The Artist Tree

    Wanna wake-and-bake during your long LA weekend? The Artist Tree dispensary is located in West Hollywood, and its Studio Lounge is open at 6 am daily. In the lounge, guests can purchase the cannabis product of their choice to enjoy onsite, as well as equipment rental to assist in consuming dabs or bong hits.

    For the ultimate baked brunch, a full menu of traditional American cuisine is also available from the nearby Kitchen24 restaurant. On Sunday mornings, the Studio Lounge features a Drag Brunch & Bubbly, sponsored by non-alcoholic THC-infused sparkling beverage brand Rickett.

    Visit The Artist Tree

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    The Woods

    The next high-end dispensary and lounge to open is The Woods, co-owned by actor and cannabis advocate Woody Harrelson.

    “We’re really excited about that,” Schmidt from Emerald Village said. “They’ve got a waterfall. They’ve got a koi pond. The garden space already existed (prior to remodeling), so they put in six or eight cabanas where people can smoke inside the cabanas and have non-combustible products in the rest of the gardens, where you can get a drink or whatnot. It’s nothing like you’ve ever seen.”

    Visit The Woods

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  • The Weedmaps guide to 420-friendly travel in Colorado

    The Weedmaps guide to 420-friendly travel in Colorado

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    In 1972, when John Denver sang out the lyrics of his chart-topping, easy-listening classic “Rocky Mountain High“(and one of two official state songs), it may have been one of the first hints that Colorado was weed-friendly. Flash forward 40 years to 2012, and the state became the first in the US to decriminalize cannabis for private consumption followed by adult-use cannabis consumption in 2014.

    But even before John Denver popularized Colorado’s mile-high beauty in song, the state had long been a draw for its natural attractions and resources, including the Rocky Mountains, Mesa Verde, and Black Canyon of the Gunnison National Parks. Chic resorts like Aspen, Telluride, and Vail attract skiers and tourists in the winter, while summer in western towns such as Durango, Grand Junction, and Colorado Springs welcomes hikers, climbers, mountain bikers, and lovers of lake and river sports.

    Now, adult-use cannabis has added another option for leisure travelers to enjoy destinations and activities, especially for those coming to visit from areas where cannabis isn’t legal.

    Travel and cannabis in Colorado

    Most cannabis-friendly attractions in Colorado are located in or near Denver, but overt advertising of 420 amenities is still low profile. Vendors that we spoke to said this was partially due to the state government’s slow progress toward regulations and permitting for public consumption facilities, as well as continued federal prohibition.

    However, “Cannabis has been a big draw to visit the state since adult-use opened in 2014. You can see this based on dispensary sales over the years. People regularly ask about cannabis lounges, cooking classes, and cannabis-infused restaurants,” said Goldie Solodar, founder and CEO of cannabis tour company City Sessions Denver

    Here are some 420-friendly destinations and activities to try in Colorado.

    420-friendly destinations and activities in Colorado

    There are more cannabis dispensaries in Colorado than there are Starbucks and Mcdonald’s combined. In cities and rural locations, retail dispensaries and cannabis tour companies are the norm and can be found with ease.

    Tetra Lounge consumption lounge — Denver

    In Denver, there are a few venues where consumption is allowed on-site. Local regulations require guest membership to access consumption facilities, which can easily be purchased or signed up for online.

    Tetra Lounge offers a retail dispensary, lounge area, and outdoor seating on their downtown rooftop. The vibe is young, urban, and appealing to visitors and locals as a safe space for consumption. Activities at Tetra include art installations, DJs, live music and socializing in the lounge’s outdoor area.

    City Sessions Colorado cannabis tours — Denver

    City Sessions is one of several tour companies in Denver that offer a variety of choices for tourists that would like to learn more about cannabis and visit dispensaries, as well as manufacturing and cultivation facilities. “Our most popular tour is Tour of The Senses,” said Solodar, “This tour is a mix of cannabis education, touring through the back end of a cultivation/grow, as well as getting out and exploring colorful Colorado.”

    City Sessions even offers rentals on top-shelf dabbing and vaping gear to out-of-towners, supplied by cannabis brands like Puffco, PAX, Volcano, and Loto.

    Marijuana Mansion installation tours — Denver

    Event and immersive art venue Marijuana Mansion offers tours of the space’s interactive, cannabis- and fantasy-themed installations.

    It’s a restored 1889 Romanesque Revival-style stone mansion in downtown Denver, and the building has been the headquarters for the Colorado branch of the Marijuana Policy Project and cannabis law firm Vicente Sederberg.

    The 4,200-square-foot mansion can host up to 150 people for large, private events. You can book 30 – 60 minute tours of the Mansion’s art installations, as well as 2 – 3 hour time slots for photo shoots.

    In Colorado Springs, visit the ELEV8 Premier glass gallery to see glass cannabis accessories being made by local artisans and even take a 4-hour glass-blowing class yourself.

    Arrowhead Manor Inn — Morrison

    Located in Morrison, Colorado — about 30 minutes from downtown Denver — is the Arrowhead Manor Inn, a cannabis-friendly hotel convenient to the Red Rocks Amphitheater. According to its website, guests of the hotel can “enjoy cannabis on a private deck or on their main decks and outdoor areas.”

    Fly Fishing the Rocky Mountains — Estes Park

    For travelers in search of a more rural experience — combined with the sport of fly-fishing — the tour company Fly Fishing the Rocky Mountains may be an excellent choice.

    Operated by Bob “Doc” Young, the company offers group and private cannabis-friendly fly-fishing classes and tours based in the town of Estes Park, about an hour and a half outside of Denver. Classes and tours start at a minimum of four hours (half-day) and include the use of flies and fly rods, snacks, drinks, and lunch.

    BEYOND show at the International Church of Cannabis — Denver

    Perhaps the most popular immersive art experience in Denver can be found at the International Church of Cannabis, which offers its BEYOND light show/meditation, with shows scheduled seven days a week.

    An officially sanctioned church, the building facility is operated by non-denominational organizers called Elevationists, and proceeds from the BEYOND show go to fund church programming, as well as contributions to local non-profits.

    Membership in the International Church of Cannabis is free and the twice-monthly invitation-only events for members, where cannabis may be consumed onsite, are also free of charge. It should be noted to visitors that the BEYOND show is family-friendly and no cannabis consumption is allowed during the show or during daily business hours.

    BEYOND is an “immersive projection map,” said Steve Berke, Elevationists co-founding member and director. “It’s a light and sound meditation with state-of-the-art technology, custom mapped on the mural that [artist] Okuda San Miguel painted. It’s the only permanent projection map installation in a church in America.”

    The church’s 35-foot ceilings and interior are almost entirely covered with San Miguel’s rainbow-colored mural that, during the show, pulsates and glows with choreographed light and laser effects. The results are hypnotic and visually stunning.

    Murals on the church’s exterior doors are painted by Los Angeles-based muralist Kenny Scharf and feature his colorful galactic fantasy creatures.

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    Joanne Cachapero

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  • Bringing marijuana to Morrison – where Red Rocks concertgoers tailgate into the night – is harder than it seems – The Cannabist

    Bringing marijuana to Morrison – where Red Rocks concertgoers tailgate into the night – is harder than it seems – The Cannabist

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    Of the thousands of revelers who head up the hill from Morrison to Red Rocks Amphitheatre to catch a show on any given night, a portion is probably high, about to get high or at least thinking about getting high.

    But one thing’s for sure — they didn’t buy their weed in Morrison.

    That’s because this tiny town of fewer than 500 — for decades the gateway to mind-altering music shows at the famous concert venue where tailgating goes down on an epic scale — doesn’t have a single pot shop.

    Read the rest of this story on DenverPost.com.

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    The Cannabist Network

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  • LivWell to be Colorado cannabis giant after powerhouse PharmaCann plans to buy boutique chain – The Cannabist

    LivWell to be Colorado cannabis giant after powerhouse PharmaCann plans to buy boutique chain – The Cannabist

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    Cannabis retailer LivWell Enlightened Health is set to dominate the Colorado market with 26 dispensaries after PharmaCann announced its plan to buy The Clinic, a boutique dispensary chain in the Centennial State.

    LivWell is a cannabis brand owned by PharmaCann — one of the biggest privately-held, vertically integrated cannabis companies in the U.S. With its roots in Colorado, LivWell currently manages 22 stores throughout the state, giving it a slight lead over other major players in the local cannabis industry.

    Comparatively, The Green Solution — a Colorado-based cannabis company — lists 20 locations on its website. Established in 2010, independently-owned Native Roots Cannabis Co. also operates 20 stores throughout the state.

    Read the rest of this story on DenverPost.com.

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    The Cannabist Network

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  • The 6 best strains for Libra season

    The 6 best strains for Libra season

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    It’s well-known among astrologists that the most charming, talented, beautiful, and of course, humble of all the zodiac signs is the Libra. I am definitely not biased because I’m a Libra.

    From September 22 to October 23, you too may be balancing feelings of delusion and narcissism with passivity and congeniality. That’s predictable Libra energy and an energy that cannabis can help you refine and utilize well past this most glorious of all zodiac seasons.

    Navigate the cannabis universe with the Weedmaps app

    Libras are represented by scales and are the only zodiac sign that’s not a thing but rather a concept: balance. And Libra is a cardinal sign, which means it heralds seasonal change with powerful transformative vibes. It’s also an air sign, which indicates intellect, creativity, and communication. Libras often end up in positions of celebrity or influence, so it’s likely you’re already in one’s orbit and/or low-key crushing on one. And who can blame you?

    Any potheads in the mood to lean all the way in and drink some of that trademark navel-gazing, galaxy-brain brilliant, balance-seeking air sign juice might want to consider trying one of these Libra-approved cultivars to activate their own inner Libra. Take it from me, an actual Libra.

    24k Gold

    A fully realized Libra is aware that they must put their needs first since this air sign has a reputation for prioritizing the needs of others. So first things first, if you’re looking to emulate the enlightened Libra experience, start by spoiling yourself with a strain named for one of the most precious of metals: 24k Gold.

    24k Gold is a cross of Kosher Kush and Tangie that reportedly delivers a smooth head high and a velvety body buzz. For consumers hoping to channel some of the stillness Libras are so well-known for weaponizing, this could be a great mood-lifting and body-soothing cultivar to explore.

    Expect a bright citrus perfume and a commensurate exhale.

    Blue Champagne

    Libras are known for being present, social, creative, and blissful. If you’re not already a Libra, Blue Champagne might help you juggle those traits as gracefully as if you actually were.

    For anyone who’d like to channel that powerful, creative aura as they lean into the more introverted, productive qualities of the season, Blue Champagne may be the perfect peppy hybrid for your autumnal stash box. It reportedly delivers a thoughtful, giggly head high that engages creativity and a fizzy body buzz that sustains focus.

    Expect a fruity sweetness in the nose and a candy-pine exhale.

    Royal Highness

    On the more manageable end of the THC spectrum is Royal Highness, a lower-potency hybrid with a reputation as a stellar daytime strain. Coming in at 13 – 15% THC on average, Royal Highness is a cross of the sativa-leaning hybrid Dance Hall and the 1:1 CBD:THC strain Respect. The resulting cultivar delivers a gently invigorating and easily managed buzz.

    Consumers report head highs that feel uplifting and euphoric and body effects that, while perky, are relaxing enough to keep the whole experience from becoming manic. Expect an earthy, sweet perfume and a woody, botanical exhale.

    Trash

    Embrace your inner Libra by acknowledging that your humanity includes less than desirable traits and finding balance for those traits can be difficult. Tap into those feels with the aptly named Trash, a cross of Purple Trainwreck and Afghani Hash Plant that delivers contemplative effects and a nuanced body buzz that is both mollifying and a little energizing.

    Bonus: Libras are notorious flirts. And because Trash has a strong reputation for arousal, a few puffs could allow you to perform your sexiest, flirty-Libra fantasies. Expect a lemon sweet perfume and a hashy, dank exhale. 

    Emerald OG

    Libra energy is aggressively charismatic, which frankly, is not universally enjoyable. And if Libra season is all about finding balance, then for some, that means blocking all those sunny waves of high-impact affability.

    Emerald OG is a deeply tranquilizing cultivar bred from Fire OG and Emerald Diesel, and the resulting effects can be profoundly sedative in both the mind and body. So when the cool fall winds feel a bit too much and you’re exhausted from everyone around you, consider a few puffs of Emerald OG. It may just recalibrate and rebalance your Libra season experience as you become one with your couch, bed, yoga mat, or floor.

    Expect a peppery, citrus funk in the nose and a spicy sweet exhale.

    Fucking Incredible

    To truly indulge the Libra season experience, you should score at least one rare strain where no one can nail the origin — like, for example, Fucking Incredible. This mysterious, pure indica strain was bred from unknown origins by Vancouver Island Seed Co., and it certainly delivers a high potent enough to justify such an arrogant name.

    Consumers report a smooth blossoming of physical effects and a cool bliss in the headspace. If Libra season is challenging you to balance public charm with private tranquility, consider being Fucking Incredible and just sleep the whole affair right off.

    Expect a pungent skunk fragrance and a skunky, herbal exhale.

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    Brianna Wheeler

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  • Study: CBD Oil Safe, Effective for Autism Patients

    Study: CBD Oil Safe, Effective for Autism Patients

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    CBD oil may represent an effective treatment option for patients with autism, according to new research published late last month.

    The case study, conducted by a team of Canadian researchers and published on August 26 in the journal Cureus, aimed “to demonstrate the use of cannabidiol (CBD) with low-dose tetrahydrocannabinol (THC) in managing symptoms associated with autism spectrum disorder (ASD) to increase the overall quality of life for these individuals and their families.”

    The study centered around a nine-year-old male patient who was diagnosed with nonverbal autism spectrum disorder who “exhibited emotional outbursts, inappropriate behaviors, and social deficits including challenges in communicating his needs with others.”

    The nine-year-old patient “required daily insulin injections, which were accompanied by self-injurious actions including head and chest punching,” the researchers said, and he “displayed inappropriate behaviors such as playing with feces and rocking on the floor for self-soothing (stimming).”

    “Since the patient was unable to attain independence at school and at home, his condition was a significant burden to his caregivers,” the researchers explained in the abstract. “The patient was treated with full-spectrum high CBD and low THC oil formulation, with each milliliter containing 20 mg of CBD and <1 mg of THC. CBD oil starting dose was 0.1ml twice daily, increased every three to four days to 0.5ml twice daily. Overall, the patient experienced a reduction in negative behaviors, including violent outbursts, self-injurious behaviors, and sleep disruptions. There was an improvement in social interactions, concentration, and emotional stability. A combination of high CBD and low-dose THC oil was demonstrated to be an effective treatment option for managing symptoms associated with autism, leading to a better quality of life for both the patient and the caregivers.”

    According to the researchers, the patient “began CBD treatments through a medical cannabis clinic at age 7.5 years starting with full-spectrum high CBD and low THC oil formulation.”

    “Within the first two weeks of starting treatment, the patient was able to fall asleep in 10-15 minutes and sleep for 8-10 hours,” they wrote. “He stopped wearing pull-up diapers as he was able to go to the washroom, wash his hands, and go back to bed without supervision, demonstrating a new behavior. There was reduced anxiety contributing to improved mood and concentration. He was able to practise gripping his pencil and trace letters. He started to follow simple instructions, such as retrieving three separate clothing items. At school, the patient received report cards with better grades and experienced less anger. This improvement allowed him to interact with his peers without signs of aggression. The patient’s mother stated, “Since starting CBD, teachers and (the) principal have noted significant positive changes. He sits for over 30 minutes, holds a marker, and is focused enough to try and trace letters or numbers. The change has been amazing for us to witness.”

    The researchers concluded that the patient “responded positively to the introduction of CBD oil treatment with reduced negative behaviors, better sleep, and improved communication.”

    “With the increasing clinical studies on the use of cannabidiol in treating patients with mood disorders, anxiety, chronic pain conditions, and other behavioral problems, it should be considered as a treatment option in managing symptoms related to autism,” they wrote. “In the case study presented, the child patient has shown behavioral and cognitive improvements with no side effects reported. Altogether, this study presents a case that motivates further research and clinical studies to understand the molecular mechanism of CBD as well as the dosing regimes for pediatric populations, the etiology of ASD, and how various dosing affect different demographics.”

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    Thomas Edward

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  • Guide to 420-Friendly Travel in California

    Guide to 420-Friendly Travel in California

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    Boom or bust, California has always been a destination for travelers of every stripe. From the ocean and forests to the foothills, mountains, high desert, and beyond, the Golden State has lots to offer visitors interested in world-famous attractions, national parks, and urban nightlife.

    The tourism association Visit California estimates that 2022 will see a 94% recovery to pre-pandemic levels of leisure travelers. Now, those leisure travelers seeking sun and fun can schedule cannabis-friendly destinations and activities on their California dream itinerary.

    Find California dispensaries and more on the Weedmaps app

    Travel and cannabis on the West Coast

    “California is setting itself up as a true cannabis vacation destination. We have seen a noticeable increase in trip-planning lately,” said Monique Jackson-Fitzgerald, CEO of the cannabis-friendly travel booking platform Inndica.

    “It has been the summer of travel,” she added. “For our visitors, coming out of the pandemic restrictions, the new travel mindset is about finding meaningful gatherings, unique destinations, and transformational experiences. We have found that there are nearly unlimited ways to pair cannabis with travel, so it’s easy to craft an itinerary that encompasses all the best of a destination’s offerings.

    After all, with its enviable climate, California contains some of the most legendary cannabis-growing regions in the world, like the Emerald Triangle located north of San Francisco, in forests and mountains that stretch from the ocean northward past the border with Oregon.

    Here are some 420-friendly destinations in California.

    420-friendly destinations in Northern California

    Once considered clandestine, visitors to Humboldt County’s Lost Coast and little towns like Mendocino and Guerneville can increasingly find “420-friendly” bed & breakfast accommodations, cannabis-infused wellness activities, and cannabis farm tours.

    Mine+Farm Inn

    “In Northern California, one of our favorite spots is Mine+Farm Inn. It’s a gorgeous property surrounded by nature. They are located next door to Korbel Vineyards (in Guerneville, California),” Jackson-Fitzgerald said. “A perfect place to pick up a vintage to enjoy with your flower.”

    Mine+Farm Inn offers organic breakfasts with ingredients sourced from local farms, as well as special dining events. Guests can easily arrange a cannabis farm tour with one of several local tour companies. “Both the Sonoma County Experience and Happy Travelers Tours are in the area and present an opportunity for visitors to explore cannabis from seed to shelf,” Jackson-Fitzgerald said.

    Oakland Cannabis Trail

    Hop on Highway 1 to make your way up the winding coast to the Bay Area and the City of Oakland, which has grown to become a hub for the state’s cannabis industry. They’re also a leader in social equity through the efforts of local pioneering cannabis businesses like Harborside dispensary and its affiliated cannabis college Oaksterdam University, as well as local women- and POC-owned small manufacturers and vendors.

    Hoping to promote the city’s cannabis renaissance, the tourist organization Visit Oakland developed the Oakland Cannabis Trail, a wandering guide through downtown Oakland, where tourists can hit a long list of cannabis retailers and attractions including interactive art, dining, shopping, and entertainment.

    “Visit Oakland launched the trail in Spring 2022, so this is a new Oakland experience,” Peter Gamez, president and CEO of Visit Oakland told Weedmaps. “There has been a lot of interest in the Oakland Cannabis Trail. It quickly became one of the top ten searches on our site and keeps climbing. The dispensaries have experienced people visiting because they’ve heard or read about the trail. We are confident this will continue to increase as the information is shared and people are more aware of their cannabis travel options when visiting Oakland.”

    “Some of the most popular experiences,” Gamez added, “have been hiking in our beautiful redwood forests, visiting the Oakland Museum of California (OMCA), and taking a self-guided art walk. The most popular activity is exploring Oakland’s diverse and amazing culinary scene,”

    Cannabis dispensaries on the trail guide include Harborside, Cookies, NUG Oakland, Ivy Hill Cannabis, and Blunts + Moore, among others. Local outdoor landmarks like Lake Merrit are included on the Trail, and several options for foodies like LJ Quinn’s Lighthouse Pub, Off the Hook Seafood & Super Burritos, Au Lounge, and Aburaya’s Japanese Fried Chicken, to name a few.

    420-friendly destinations in Central California

    For all-inclusive cannabis getaways, buzz over to the central California coast.

    Higherway Travel

    Higherway Travel is based out of Grover Beach in San Luis Obispo County, near Pismo Beach and Morro Bay. Its co-founder, April Black, has organized cannabis travel tours and special events since the early 2000s and said that she also has recently seen an increase in inquiries for some of Higherway’s popular tours, which are offered in Central and Northern California, Hawaii, and, previously, even in Europe.

    For the destination event traveler, Black can custom-design a curated cannabis experience to suit any occasion, including bridal showers, weddings, birthdays, and group trips, as well as help guests coordinate accommodations and schedule local activities, “With so many people going ‘California Sober,’ many are opting out of gatherings that include alcohol,” Black told Weedmaps. “I had a group of senior ladies for a private yoga class, and they were absolutely a joy. With private yoga, I come to you with everything. That experience includes mats, blankets, straps, blocks, aromatherapy, music, CBD topicals to try, edibles, smoke sesh, and, of course, yoga.”

    Curated events range in price depending on what kind of activities guests would like to experience; elaborate, all-inclusive weekends can start at $1,000 and may include wine tasting, a visit to local hot springs, spa treatments, gourmet cuisine, and a round of golf. Black attempts to accommodate every request.

    “That is the best part about being a cannabis tour guide — the sky’s the limit,” she said.

    420-friendly destinations in Southern California

    In Southern California, Jackson-Fitzgerald said that the Coachella Valley is heating up with lots of options for a high desert holiday, whether you’re into health and wellness or lounging like a lizard.

    Desert Hot Springs Inn

    “There are dozens of consumption lounges, delivery services, and canna-friendly hotels. Desert Hot Springs is home to a couple of the first (hotels), and they roll out a green carpet welcome,” Jackson-Fitzgerald shared. “If you are looking for an escape, walk through the gates of Desert Hot Springs Inn, and leave the rest of the world behind. DHS Inn is also dog-friendly. Bring the pooch, and they can romp in the enclosed dog run or hang with you in the fully fenced backyard.”

    Because rules and regulations vary by municipality throughout the state, weed-friendly hotels in California are few and hard to find. That said, Desert Hot Springs Inn has officially listed “cannabis-friendly” on its website’s list of amenities. The hotel also features natural mineral water from local hot springs piped into the hotel’s courtyard pool and spa facilities.

    Local mineral hot springs have been an attraction there since the 1940s, and Desert Hot Springs is California’s official Spa City. Today, CBD oil can be infused into one of the hotel spa’s menus of massage treatments for an added topical application of relaxation. When ready for a night on the town, the mid-century glamor of Palm Springs is only 15 minutes away.

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    Joanne Cachapero

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