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Category: Cannabis

Cannabis | ReportWire publishes the latest breaking U.S. and world news, trending topics and developing stories from around globe.

  • Cannabis Workouts Are Becoming The New Weekend Ritual

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    Cannabis workouts are becoming the new weekend ritual, blending wellness, movement, mindfulness, and social connection for active lifestyles.

    Saturday mornings used to mean sleeping in or scrolling through phones in bed. Now, for a growing number of wellness-minded consumers, weekends begin with a stretch, a scenic trail, and a carefully measured dose of cannabis. From yoga mats in the park to group hikes and pickleball courts, cannabis workouts are emerging as a social, feel-good ritual that blends movement, mindfulness, and a touch of euphoria.

    The shift reflects a broader evolution in cannabis culture. Gone are the days when cannabis was synonymous with couch lock. Today’s consumers, especially millennials and Gen Z, are embracing low-dose THC and CBD products to enhance body awareness, motivation, and enjoyment during physical activity. The goal isn’t to get high and zone out; it’s to tune in to the rhythm of movement and the pleasure of being present.

    RELATED: How Canada Became the World’s Cannabis Superpower

    Weekends provide the perfect testing ground. Without the pressure of a workday schedule, people feel freer to experiment with microdosing before a yoga class, a long walk, or a bike ride. Many enthusiasts report that a small amount of THC helps them ease into exercise, quiet mental chatter, and stay engaged longer. CBD-dominant options, meanwhile, are popular for reducing post-workout inflammation and supporting recovery.

    Social connection is a major driver of the trend. Instead of meeting friends for brunch mimosas or late-night drinks, groups are gathering for “puff and pilates,” trail walks, or backyard mobility sessions. The vibe is less about competition and more about shared experience. Laughter comes easily, conversations flow, and the focus shifts from performance to enjoyment.

    Fitness professionals are beginning to take notice. Some trainers say clients who use low doses of cannabis report improved mind-muscle connection and a greater sense of flow during repetitive activities like running or swimming. Others emphasize the importance of moderation and safety: staying hydrated, avoiding unfamiliar or high-risk exercises, and understanding personal tolerance levels.

    Outdoor activities are particularly popular. A gentle buzz can heighten sensory awareness, making colors seem more vivid, music more immersive, and fresh air more invigorating. For many, this transforms routine exercise into something closer to play. A neighborhood walk becomes an exploration. A stretch session turns into a meditative reset.

    As cannabis legalization expands and stigma continues to fade, the intersection of fitness and responsible consumption is likely to grow. Brands are responding with low-dose edibles, fast-acting beverages, and CBD recovery products designed with active lifestyles in mind. Meanwhile, communities are forming around shared values of wellness, balance, and mindful enjoyment.

    RELATED: Science Confirms Choosing Joy Boosts Mind and Body

    For those curious about trying a cannabis workout, the key is to start low and choose familiar activities. A gentle yoga flow, an easy hike, or a relaxed bike ride can offer a safe introduction. The point isn’t to push limits, but to rediscover movement as something joyful.

    In a culture often treating exercise as punishment and weekends as recovery from stress, cannabis workouts offer a different narrative. They invite people to slow down, connect with their bodies, and turn movement into a ritual worth savoring.

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    Amy Hansen

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  • Australian Cannabis Party Update, ” NSW Parliament is Back and Jeremy Hit the Ground Running” | Cannabis Law Report

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    They write

    Parliament has just resumed for 2026 and Jeremy Buckingham has wasted no time getting straight to work.

    Cannabis Inquiry: Cross-Party Agreement on Reform

    Last week, as Chair of the inquiry into the Impact of the regulatory framework for cannabis in NSW, Jeremy formally reported the committee’s findings to Parliament.

    The findings and recommendations were supported by a number of Labor, Liberal, Libertarian and Shooters Party MPs.

    The inquiry examined the real-world impact of current cannabis laws, including the criminal justice costs associated with prohibition. The evidence is clear: the existing framework is expensive, inefficient, and no longer fit for purpose.

    Importantly, the committee agreed on a staged approach to legalisation a practical, structured pathway forward.

    You can read more about the inquiry and its recommendations here:
    https://www.parliament.nsw.gov.au/committees/inquiries/Pages/inquiry-details.aspx?pk=3043

    Pill Testing and Fixed Sites

    After the tragedy at the Dreamstate music festival recently, Jeremy was compelled to speak in Parliament to push for the continuation of pill testing at music festivals and the establishment of fixed drug checking sites across NSW.

    If the goal is harm reduction and public safety, these services need to be permanent, accessible, and properly supported, as they already are in other jurisdictions.

    Evidence-based policy saves lives. Prohibition does not.

    The year has only just begun, and the momentum is building.

    The legalisation of cannabis is firmly back on the parliamentary agenda.

    https://www.legalisecannabis.org.au/nsw_parliament_is_back_and_jeremy_hit_the_ground_running?utm_campaign=february_2026_newsletter_subsc&utm_medium=email&utm_source=legalisecannabis

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    Sean Hocking

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  • Cannabis And Creativity Are Becoming The Coziest Trend

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    Cannabis and creativity are becoming the coziest trend, as Millennials and Gen Z embrace relaxing, hands-on hobbies.

    Move over wake-and-bake. A quieter marijuana movement is taking shape in living rooms, craft studios, and community spaces across the country. Cannabis and creativity are becoming the coziest trend. Millennials and Gen Z consumers are increasingly pairing cannabis with creative hobbies like pottery, journaling, Lego building, watercolor painting, and music production. The shift reflects a broader cultural move toward mindfulness, slow living, and experiences prioritizing self-expression over intoxication.

    Instead of nightlife and party scenes, younger adults are embracing what some are calling “high hobbies” — activities blending low-dose cannabis use with tactile, screen-free pastimes. The appeal is simple: these hobbies offer stress relief, a sense of accomplishment, and a chance to disconnect from constant digital noise.

    RELATED: Immersive Events Redefine Millennial Nights

    On social platforms like TikTok and Reddit, posts tagged with cozy crafting and cannabis routinely rack up millions of views. Videos show users assembling intricate Lego cityscapes, filling bullet journals with colorful layouts, or shaping clay on pottery wheels, all while describing how a small amount of cannabis helps them relax into the creative process. The vibe is less about getting stoned and more about finding flow.

    Mental health plays a major role in the trend’s popularity. Surveys consistently show younger generations report higher levels of anxiety and burnout than their predecessors. High hobbies provide a gentle antidote: repetitive motions like knitting or coloring can calm the nervous system, while cannabis in modest doses may reduce inhibition and encourage experimentation. Together, they create a low-pressure environment where perfectionism takes a back seat to play.

    Photo by Cappi Thompson/Getty Images

    Artists and hobbyists often describe cannabis as a “creative companion” rather than a productivity tool. A Seattle-based illustrator who hosts monthly craft nights says attendees are less concerned about making something perfect and more focused on enjoying the process. Participants bring sketchbooks, embroidery hoops, or miniature model kits, and the shared activity fosters a sense of community many say has been missing since the pandemic years.

    Dispensaries and studios are beginning to take notice. In states where cannabis is legal, some retailers are partnering with local artists to host paint nights, pottery workshops, and DIY terrarium classes. These events mirror the popularity of wine-and-paint gatherings from the 2010s, but with a modern twist resonating with wellness-focused consumers.

    The science behind cannabis and creativity remains nuanced. While high doses can impair memory and focus, low doses of THC may increase divergent thinking — the ability to generate multiple ideas or solutions. Researchers also point to cannabis’s effects on sensory perception, which can make textures, colors, and sounds feel more vivid, enhancing hands-on activities.

    RELATED: Science Confirms Choosing Joy Boosts Mind and Body

    For those curious about trying a high hobby, moderation is key. Experts recommend starting with a low dose, choosing a comfortable environment, and selecting activities emphasizing process over outcome. Coloring books, journaling prompts, simple watercolor sets, and beginner Lego kits are popular entry points because they require minimal setup and encourage experimentation.

    Ultimately, the rise of high hobbies reflects a generational shift in how cannabis fits into daily life. Rather than centering social status or escapism, Millennials and Gen Z are weaving it into rituals of creativity, relaxation, and connection. In a fast-paced world defined by notifications and deadlines, the simple act of shaping clay, snapping bricks together, or filling a blank page can feel quietly revolutionary — especially when paired with a little help unwinding.

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    Sarah Johns

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  • New York Opens The Door For Consumer Convenient THC Drinks

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    New York opens the door for consumer convenient THC drinks, signaling a shift toward safer, regulated, and accessible cannabis options.

    TO the surprise of many, New York opens the door for consumer convenient THC drinks. The Empire State is taking another step in the evolution of its legal cannabis market by opening the door to regulated THC-infused beverages. After a rocky rollout of licensed dispensaries frustrating businesses and consumers alike, state leaders are signaling a more pragmatic, consumer-focused approach designed to improve access while maintaining safeguards.

    When New York legalized adult-use cannabis in 2021, the state promised an equity-driven marketplace prioritizing justice-involved entrepreneurs and communities disproportionately impacted by prohibition. While widely praised in principle, the rollout proved to be a logistical and legal tangle. Lawsuits over licensing criteria, delays in opening retail locations, and the proliferation of unlicensed shops created confusion for consumers and undercut the regulated market.

    RELATED: How Canada Became the World’s Cannabis Superpower

    At one point, illegal storefronts vastly outnumbered licensed dispensaries, selling untested products without age verification or quality controls. Regulators were forced to pivot, launching enforcement crackdowns and streamlining licensing to stabilize the market. Over the past year, New York has made measurable progress, with more licensed stores opening and enforcement actions reducing the visibility of illicit operators.

    Now, policymakers are turning their attention to a fast-growing segment of the cannabis industry: THC beverages. Typically made with hemp-derived cannabinoids and limited to low doses of THC, these drinks have surged in popularity nationwide as consumers seek alternatives to alcohol offering a milder, more predictable experience.

    Photo by Karolina Grabowska from Pexels

    By allowing regulated sales of THC beverages through controlled channels, potentially including venues already licensed to sell alcohol, New York is acknowledging a key consumer trend: people want convenient, safe, and socially acceptable ways to consume cannabis. For many adults, a low-dose THC seltzer or cocktail offers a familiar format fitting seamlessly into social settings.

    For consumers, the shift could mean dramatically easier access. Instead of navigating a patchwork of dispensaries—some distant, some with limited hours—adults may soon be able to purchase regulated THC drinks in more familiar retail environments. Clear labeling, dosage limits, and age verification requirements would provide confidence in product safety and consistency.

    The move also reflects lessons learned from the state’s difficult cannabis rollout. Early policies prioritized structure over usability, leaving consumers to navigate a system technically legal but practically inconvenient. By contrast, integrating low-dose THC beverages into established retail frameworks demonstrates a more mature regulatory stance balancing public health, market demand, and economic opportunity.

    RELATED: Science Confirms Choosing Joy Boosts Mind and Body

    Industry observers note THC drinks are one of the fastest-growing segments in legal cannabis, appealing to wellness-minded consumers, social drinkers seeking alcohol alternatives, and newcomers wary of traditional cannabis products. New York’s embrace of this category could help channel demand into the regulated market, reducing the appeal of unlicensed sellers while generating tax revenue.

    While details are still being finalized, the direction is clear: New York is moving from a turbulent launch toward a more consumer-friendly cannabis ecosystem. If implemented effectively, the expansion of THC beverages could mark a turning point, making legal cannabis not only accessible but practical for everyday adults seeking safer, regulated options.

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    Sarah Johns

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  • Nothing Ventured, Nothing Gained: Bob Weir and Cannabis Culture

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    This piece is, first and foremost, a tribute to Bob Weir, and to a life spent creating, persisting, and refusing stasis. It reflects on the influence of an artist whose impact was not confined to charts, movements, or moments, but unfolded over decades through presence, continuity, and an uncommon willingness to keep going. Weir’s work, approach, and longevity shaped not only a musical lineage but a way of participating in culture that favored openness over control and evolution over preservation.

    Viewed through that lens, the story also traces the evolution of cannabis from informal social practice to regulated commercial enterprise, and the tensions that transformation has produced. It considers how cannabis culture was sustained long before it was monetized, how community-based norms differ from institutional frameworks, and how scale, capital, and compliance can both legitimize and distort what they seek to protect. Interwoven are reflections on risk, longevity, decentralization, and influence without authority, while using Bob Weir’s path as a reference point for understanding what the cannabis industry has gained, what it has compromised, and what lessons may still be recoverable.

    ******

    “The bus came by and I got on—that’s when it all began.”

    Before the Law Caught Up With the Culture

    Before cannabis was regulated, branded, taxed, and debated in committee rooms, it lived where Bob Weir lived: in parking lots and passenger vans, in half-lit arenas and muddy fields, passed hand to hand with the same unspoken trust as a lighter or a lyric. For the Grateful Dead, cannabis wasn’t a cause or a commodity, it was part of the shared language of curiosity, patience, and community. Bob Weir didn’t preach it. He inhabited it. And in doing so, he helped normalize a culture long before the law ever caught up.

    It was 1963, and Bob Weir was sixteen years old when he met Jerry Garcia at Jerry Morgan’s Music Store in Palo Alto, California. Jerry was playing the banjo; Bobby heard the sweet sounds.  Bobby walked in, leading to a marathon jam session and the start of their musical journey together. Bob was just a kid with a guitar and an instinct. That accidental meeting didn’t just spark a band; rather, it ignited a culture, a community, and a way of thinking that would ripple through American music, counterculture, and cannabis history for decades.

    The Grateful Dead didn’t arrive fully formed. Neither did the movement that grew around them. It was improvised, communal, messy, joyful, and defiantly human. Bob Weir would become one of the most singular rhythm guitarists ever to stand on a stage; his rhythm guitar playing is isolated in numerous online recordings; take a listen…mind-blowing. He was angular, conversational, intentionally off-center. While he often dominated the stage, he didn’t dominate the music. He challenged it. He complicated it. He kept it alive. 

    Over more than six decades, Bob Weir never stopped.  The band kept playing on.  

    The Long Road After Jerry

    The Grateful Dead. Kingfish. Bobby and the Midnites. RatDog. Weir & Wasserman—anchored by the late great Rob Wasserman on stand-up bass. Dead & Company. Wolf Bros. Orchestral collaborations. Solo tours. Side projects that became lifelines. Once asked why he always had so many side projects, Bob simply said, “Because I love to play.” While others slowed down, retired, or calcified into nostalgia, Weir stayed restless. He toured relentlessly. He experimented openly. He trusted the road.

    And when he passed, the music didn’t end, it won’t end, but the silence hits hard.

    Bob Weir wasn’t just a legend to me. He was my compass.

    I didn’t realize it at first, but I modeled so many parts of my life after him. Bob was a man of few words. Quirky. Aloof. Sometimes misunderstood. Often underestimated. But always himself. And always moving forward. Bob mused romantically about being a cowboy, as did I when I moved to Wyoming in 1998; this is the source of inspiration for so many Dead cowboy tunes. I once wrote a legal article titled “Victim or the Crime,” focused on hate crime legislation. My professional writing, including my Forbes columns over many years, always includes dedicated Grateful Dead lyrics. We named our daughter, Cassidy!    

    When Jerry Garcia died in 1995, I was just starting to appreciate Grateful Dead tours and just beginning to understand how deeply cannabis, music, and community were braided together in the Dead universe. At the time, the Dead were already a thirty-year institution, but the scene felt timeless. Parking lots turned into temporary cities. A traveling carnival. A shared hallucination built on music, curiosity, kindness, and cannabis. Massive drum circles under overpasses with balloons bursting and nitrous tanks hissing in the background. It was a rainbow full of sound, with fireworks, calliopes and clowns. Everybody’s dancing.

    The music was electric. Cannabis smoke drifted easily and unapologetically through the air. The crowd was multigenerational, with eight-year-olds and eighty-eight-year-olds dancing side by side. The culture was welcoming and alive. It welcomed my friends and me. After attending Catholic school for so long, it opened us up.  

    That summer, with my buddies, Lew and Jason, I drove from home in South Jersey to RFK Stadium in Washington, D.C. for a Dead show—June 24, 1995. Cannabis fueled our drive down I-95. This wasn’t a statement or a rebellion; it was simply part of the atmosphere. At the time, we mostly knew the studio albums, which, as any Deadhead knows, is not where the band truly lived. The Grateful Dead were a live organism.

    None of us had a reliable car. I borrowed my Dad’s Mazda 929—a massive, plush four-door sedan built for comfort, not rebellion. We loaded it with CDs and Dead show cassette recordings. Tape trading was everything back then. You’d visit the Woodstock Trading Company in South Jersey, request shows that you picked from the book, DeadBase, drop off blank tapes, and wait weeks. When those tapes came back, it felt like treasure.

    The Dead encouraged it. They created taper sections. They allowed recording. Music was meant to travel, to be shared, not controlled; the same quiet social contract that governed cannabis in the Dead world: communal, trust-based, and defiantly outside permission structures. Music was meant to travel, to be shared, not controlled. Some people built entire lives around those tapes. In hindsight, that philosophy mirrored cannabis culture perfectly, as it was decentralized, trust-based, and community-driven.

    Driving south on I-95, buses and semis flying past us, we listened, and we argued.

    Who really was this boisterous, deep-voiced frontman? The one who sounded cocky. Abrasive.  Maybe even obnoxious. Who did he think he was?  Not Jerry.

    Back then, the jury was out on Bob Weir.

    That wasn’t uncommon. Deadhead culture had a long tradition of skepticism toward Bobby. The short shorts. The swagger. The songs that didn’t always land. I remember parking-lot T-shirts featuring a block of Velveeta cheese that read “Cheese it up, Bobby.” Bobby was often perceived as cheesy; as rockstar Bobby.

    Jerry, by contrast, was untouchable. He was the gentle guitar wizard, the spiritual center. In comparison, Bobby seemed brash.

    And then the show started.

    “Jack Straw” opened.

    By the end of that night, everything we thought we knew was wrong.  We returned to Georgetown, where we were staying, our skin stained green from the $5 tie-dyes we’d bought in the parking lot. We dove deeper into the Bob Weir songbook.  

    We listened differently. We leaned in. We started chasing Bob Weir songs—deep cuts, risky ones, sometimes flawed ones. “My Brother Esau.” “Picasso Moon.” “Festival.” Even the misfires mattered. Bob always added something. He never diluted the band, even when the audience wasn’t ready.

    During a concert, the Dead had a rhythm where there was a Jerry song, Bobby song, back and forth. Not a rule, just the way it most often unfolded. And the philosophy of the Dead was one where everyone got to shine; everyone got to play lead, in effect. This was the Bobby mentality.  Slowly, Bobby won us over. Eventually, for many of us, he became the anchor.

    This era followed In the Dark, the band’s first true commercial success. “Touch of Grey” cracked the pop charts. And if you want to understand why Bobby caught heat, just watch the online video for “Hell in a Bucket.” That explains a lot.

    Then Jerry died.

    For many of us, it felt like the end. And unfortunately, for many of us, it was just about the beginning of our love for this band. After all, it was a band beyond description. Were they ever here at all?

    Photo courtesy of Facebook

    The Music Never Stops

    Around that same time, my father remarried. At the wedding, my Uncle Jimmy mentioned a band called RatDog—and how much he loved Bob Weir. Who knew?  RatDog was Bob’s new band, and it was different. A horn section. A new groove. Same soul. It brought the road back to life. Many of us fell in love…again.  

    Show after show. City after city. As many as I could afford as a student. We chased Bob Weir around the country. I even formed my real estate company, Weir Here LLC. W-E-I-R became my four-digit PIN.

    Bob stayed on the road. Always. It’s been said that no one has played more live concerts than Bob Weir. Whether or not it is literally true, no one has played more large-scale shows over more decades with more consistency.

    The music never stopped.

    RatDog album Evening Moods remains one of the most underrated albums of that era.  It is brilliant from start to finish. You won’t find it easily on major streaming platforms, but it lives on YouTube. Like much of the Dead universe, it survives because people care enough to keep it alive.

    In April 2008, RatDog closed its Spring tour at the Beacon Theatre in New York City. I flew back from law school in the West to meet friends from New York and Philadelphia. Three nights. Transcendent. Those setlists can be found on setlist.fm —go look it up. Fantastic!

    After the last show of that run, my friends and I walked out buzzing, drifting north toward 72nd and Amsterdam on the Upper West Side. Standing in a circle outside a bar, decompressing, smoking, telling stories. A Lincoln Town Car pulled up. The door flew open. A man barked something into the back seat— “There will be repercussions,” the man said.  He slammed the door, and stormed through our group, inadvertently shoulder-checking my friend Jason.

    It was Bob Weir.

    He asked to bum a cigarette. We obliged. Turns out the band had rented the back room of that bar for their end-of-tour gathering.

    Four Words That Changed Everything

    Later, in the men’s room, guess who arrives at the urinal right next to me? Standing shoulder to shoulder at a urinal, I couldn’t help myself.

    “Bobby—amazing tour. RatDog is incredible. Please keep playing. You have no idea what it means to so many people.”

    Silence.

    He zipped up, stepped back, looked me dead in the eye, and said:

    “Nothing ventured. Nothing gained.”

    And walked away.

    Four words.

    I didn’t understand them that night. But they followed me.

    In 2008, my Philadelphia Phillies won the World Series. That same year, my mother died from pancreatic cancer. I had two young children—four and six. I was working at a prestigious law firm in Denver and deeply unhappy. Every option felt safe. None felt right.

    Nothing ventured. Nothing gained.

    These four words inspired me to start my own firm—a law firm centered around ‘canna-business.’ Over the next fifteen years, it grew into the first and largest cannabis-only business law firm in the world—the Hoban Law Group.

    All from a sentence spoken in a bathroom.

    Culture Before Compliance

    Now, Bob Weir was never a policy guy. No podiums. No white papers. He didn’t need them.

    Some revolutions start in parking lots.

    Cannabis culture didn’t begin with licenses, capitalization tables, or compliance manuals. It began with community. The Grateful Dead didn’t market cannabis—they normalized it. Quietly. Organically. Humanly.

    The Dead lived defiance rather than preaching it. Their Haight-Ashbury home was raided in the 1960s. That wasn’t a scandal; it was a rite of passage. Cannabis wasn’t branded. It was passed. Shared. Laughed over. Trusted.

    Culture always comes before regulation.

    Bob’s relationship with cannabis was never performative. In a 1981 interview, Bob once said that “I am absolutely never stoned on stage…I can’t play stoned…,” as Jerry looked on with a wry smile, and a raised eyebrow of disbelief.  When Bob spoke about it, it was sideways—through humor, memory, and civic responsibility. Vote. Pay attention. Don’t let outdated laws calcify simply because power is comfortable.

    He understood something critical: legitimacy without memory becomes control.

    The Dead’s world was decentralized, communal, and improvisational. Today’s cannabis industry is centralized, capital-intensive, and often hostile to the very communities that carried the plant through prohibition. That tension matters.

    Bob Weir never positioned himself as an architect of modern cannabis markets. And that absence is telling.  Because commercialization is not liberation. Regulation is not justice.

    What Bob and the Dead provided was social permission; the kind that makes prohibition untenable long before laws change. They made it impossible to pretend cannabis users were outsiders.

    Even “420” didn’t come from marketers or regulators. It came from kids, from Dead-adjacent culture, passed hand to hand as a code. Culture first. Always.

    A Legacy That Couldn’t Be Licensed

    Today, as cannabis inches toward federal reform and grapples with normalization, Bob Weir’s legacy sits quietly beneath the surface. The plant survived not because it was profitable, but because people loved it, trusted it, and refused to let it be erased.

    You can license cannabis. You can tax it. You can regulate it. But you can’t unteach people what they already know.  

    Bob Weir didn’t walk this road alone. Every long strange trip has its translators. These were the people who turned music into language, instinct into principle, and culture into something durable enough to survive the future. For the Grateful Dead, one of those translators was John Perry Barlow: lyricist, digital freedom pioneer, and Bob Weir’s close friend and collaborator.

    I went to law school in Wyoming, which was Barlow’s home state. And one day at the University of Wyoming, outside of a restaurant, I saw an older man in a long leather coat, arguing intensely into a cellphone. Familiar energy. The same posture. The same refusal to bend.

    I was having a smoke. He moved in. Introduced himself. John Perry Barlow. He was in town talking about cyberspace freedom, which is another frontier where culture would once again outrun the law.

    Same instinct. Same resistance. Same thread. We talked about the songs and how they never really stop living.

    Over the years, there was Dead50 in Chicago, with Phish’s Trey Anastasio. Great shows that I am proud and lucky to have attended. Numerous Playing in the Sand events on the Riviera Maya. Then, Dead and Company with John Mayer began. Ten years and dozens of Dead & Co. shows under my belt soothed my soul. Cannabis brought me to Las Vegas to teach at UNLV’s Cannabis Policy Institute, and I was able to attend numerous Dead Forever shows at the Sphere…what an experience!  

    And all through 2025, the music definitely lived on. While traveling internationally for my cannabis industry work, I found myself in London while Bob Weir and the Wolf Brothers were playing at the Royal Albert Hall with the Royal Philharmonic Concert Orchestra. In typical Bobby fashion, questionable setlist choices, but an amazing experience. And then there were the final shows in Golden Gate Park—Dead60. These turned out to be his final shows. A fitting end to a career that ended exactly where it began. I was proud to see it all happen live.  

    Music was meant to travel, and to be shared, not controlled. The Grateful Dead understood that instinctively. It’s why tapers were welcomed, why the music spread hand to hand, city to city, generation to generation. It was decentralized by design, governed by trust, sustained by community rather than permission.

    Cannabis followed the same path. Long before licenses, compliance manuals, capitalization tables, and quarterly earnings calls, the plant survived because people shared it. Quietly. Reliably. Outside formal structures. Culture carried it when the law would not.

    Today’s cannabis industry has achieved something remarkable: legitimacy. That matters. Regulation, when done right, protects consumers, creates stability, and ensures longevity. But in the rush toward scale and standardization, there is a real risk of forgetting what made legalization inevitable in the first place. Commercialization is not liberation. Regulation is not justice. And an industry that loses sight of its cultural roots risks becoming legal, and hollow.

    Bob Weir never tried to control the music. He trusted it to move on its own. That may be the lesson still waiting to be learned.

    Bob Weir wanted the songbook—the soundtrack of our lives—to survive three hundred years.

    I believe it will.

    Eight-year-olds. Eighty-eight-year-olds. Still dancing.

    We grew up with Jerry, but we grew old with Bobby. And for that we will all forever be Grateful.  

    Vaya con Dios, Ace.

    Nothing ventured. Nothing gained.

    This article is from an external, unpaid contributor. It does not represent High Times’ reporting and has not been edited for content or accuracy.

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    Bob Hoban

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  • Karma Koala Podcast 291: Alice O’Leary Randall – Medical Cannabis Pioneer on Momentous Change But Where To Next? | Cannabis Law Report

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    DOWNLOAD FOR FREE AT PODOMATIC

    https://www.podomatic.com/podcasts/karmakoalapodcast/episodes/2026-02-19T06_34_04-08_00

    An honour, or as I’m in the US i should say honor, to speak with Alice who with her husband Robert changed the paradigm back in 1976 as they ignored the word “impossible” and brought into reality the US’s first medical cannabis prescription since 1937!

    For the last 50 years Alice has been working to build on that development

    Read all about it here https://www.aliceolearyrandall.com/

    We chat through the hows’, whys’ and whereforefores and then jump into Alice’s thoughts about cannabis regualtion in the USA in 2026.

    • Where are we?
    • Why are we here?
    • What’s good?
    • What’s bad?
    • Where do changes need to be made?

    We discuss human rights and medical cannabis, creating change at federal and/or state level and lots lots more

    Profound thanks to Alice for speaking with the Koalas we are somewhat in awe and had to chew a lot of eucalyptus ag=fter our conversation to calm down from all the excitement of talking with a cannabis legend.

    Robert

    Working together

    My late husband, Robert C. Randall, is the acknowledged founder of the modern American medical marijuana movement. In 1976 he became the first American to obtain federal supplies of marijuana for medical purposes (he had glaucoma). For several years he was the ONLY individual receiving such access and he often said he felt like “the only one to make the lifeboat.” For more than two decades we worked to remove the prohibitions against marijuana’s medical use and we had great successes.

    Robert died in 2001 and for a decade I took a break from the medical marijuana issue, pursuing my personal interest in hospice and working with Tidewell Hospice in Sarasota, FL for six years.

    In the autumn of 2012 I decided to retire. 2013 was a busy time as I renovated property in Western North Carolina and began to re-engage the medical cannabis issue. In 2014 I completed my autobiography, “Medical Marijuana in America: Memoir of a Pioneer.” It is available on Amazon.com. In 2015 I began a five year collaboration with Mary’s Medicinals of Denver working as a traveling ambassador and writer. I developed Mary’s Cannabis Primer and Mary’s Prime Time. In 2019 I wrote Pain-Free with CBD, published by Rockridge Press. The pandemic put an end to my traveling ambassador days. Today I am an instructor with the Pacific College of Health & Science in their cannabis certification program. To learn more about me please visit www.aliceolearyrandall.com

    https://www.linkedin.com/in/aliceolearyrandall/

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    Sean Hocking

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  • Hawaii Senators Take Up Cannabis Legalization Bills After Key House Lawmakers Signal Reform Is Dead For 2026 Session | Cannabis Law Report

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    Marijuana Moment

    Hawaii senators have taken up a pair of bills to legalize marijuana—with one proposal contingent on federal reform or changes to the state Constitution and the other omitting provisions allowing for commercial sales.

    Members of the Senate Health and Human Services Committee and Commerce and Consumer Protections Committee took up the measures—SB 2421 and SB 3275 from Sen. Joy San Buenaventura (D)—at a joint hearing on Tuesday.

    The panels also discussed separate legislation allowing for the sale of certain hemp-derived cannabinoid products and permitting one-time medical cannabis sales for patients with pending registration applications.

    The hearing comes after key House lawmakers signaled that legalization proposals that originated in that chamber would not be advancing in the 2026 session, citing a lack of sufficient support to get them crossed over and potentially enacted.

    In the Senate, SB 2421 would create a Hawaii Cannabis and Hemp Office within the state Department of Commerce and Consumer Affairs to oversee the regulation of a adult-use cannabis market if there’s a constitutional change at the state level or change in federal marijuana laws permitting such a reform.

    “In addition to legalizing medical use cannabis, numerous states and jurisdictions, including Hawaii, have opted to decriminalize the possession of small amounts of non-medical use cannabis,” the bill text states. “These decisions are motivated by a variety of compelling reasons, including the prioritization of more serious crimes, advancements in criminal justice reform, evolving public opinion, and long-standing social equity concerns within the context of cannabis regulation.”

    The legislation also notes that states with legal cannabis markets “have witnessed substantial benefits from the revenue generated through taxes, including use and licensing fees, as well as general excise and sales taxes on the non-medical adult-use cannabis industry.”

    “In light of the task force report, the legislature finds that the legalization of cannabis for personal use is a natural, logical, and reasonable outgrowth of the current science of and attitude toward cannabis. The legislature further finds that cannabis cultivation and sales hold the potential for economic development, increased tax revenues, and reduction in crime. Accordingly, the legislature is prepared to move forward with the legalization of non-medical adult-use cannabis if specific changes are made at the federal level or if the electorate approves a state constitutional amendment to legalize cannabis.”

    The state attorney general’s office submitted testimony ahead of Tuesday’s hearing, recommending a series of changes related to hemp provisions, packaging requirements and penalties for the unlawful sale of cannabis to minors, for example.

     

     

    Read more at 

    Hawaii Senators Take Up Marijuana Legalization Bills After Key House Lawmakers Signal Reform Is Dead For 2026 Session

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    Sean Hocking

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  • How Canada Became the World’s Cannabis Superpower

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    How Canada became the world’s cannabis superpower, dominating exports and setting global standards for legal cannabis production.

    Once viewed as a social policy experiment, it has evolved into a global economic force. Here is how Canada became the world’s cannabis superpower. Nearly eight years after nationwide legalization, the country now leads the world in legal cannabis exports, pharmaceutical-grade production, and regulatory standards — a position reshaping international trade and influencing policy debates far beyond its borders.

    When Canada legalized recreational cannabis in 2018, it became the first G7 nation to do so nationwide. That move provided a decisive first-mover advantage. Canadian companies built compliant supply chains, secured federal oversight, and invested heavily in high-tech cultivation facilities designed to meet strict medical standards.

    RELATED: Feds Reveal Medical Cannabis Is Very Popular With The Disabled

    Today, Canada dominates the legal export market, shipping medical cannabis to Europe, Australia, Israel, and Latin America. Germany has emerged as one of the most important destinations, with Canadian producers supplying a significant share of its imported medical cannabis as patient demand grows faster than domestic production.

    Unlike the United States — where federal prohibition still blocks international trade — Canada’s unified national framework allows companies to export legally, giving them a structural advantage in global markets.

    Photo by Yarygin/Getty Images

    Cannabis has become a major pillar of Canada’s economy. The legal sector contributes billions annually to national GDP and supports hundreds of thousands of jobs across agriculture, logistics, retail, and pharmaceutical research.

    Exports are an increasingly important piece of the economic impact. As domestic markets mature and retail prices soften, international sales provide higher margins and long-term growth opportunities. Pharmaceutical-grade cannabis products, oils, and extracts are especially valuable in medical markets where safety and consistency are paramount.

    Tax revenue from cannabis sales also funds public programs and enforcement, further embedding the industry into Canada’s fiscal landscape.

    Several factors explain Canada’s leadership position:

    • Federal legalization which enables international trade
    • Strict regulatory oversight building global trust
    • Advanced cultivation technology and quality control
    • Access to capital through public markets
    • Compliance with EU pharmaceutical standards

    RELATED: Science Confirms Choosing Joy Boosts Mind and Body

    Together, these advantages have made Canadian cannabis a global benchmark for safety, reliability, and medical quality.

    Canada may lead, but it is no longer alone in shaping the global cannabis economy.

    The United Kingdom has become a major exporter of medical cannabis products, while Israel continues to set the pace in research and clinical innovation. Portugal has emerged as a cultivation hub for European markets, attracting multinational investment due to its climate and regulatory environment. Uruguay, the first country to legalize recreational cannabis, maintains a growing export presence. Meanwhile, countries such as Colombia, Australia, and Morocco are expanding legal production, betting on lower costs and favorable growing conditions to compete globally.

    RELATED: Native American Tribes Find Economic Power In Alcohol, Cannabis And More

    Despite its leadership, Canada’s cannabis industry faces mounting challenges. Price compression, regulatory complexity, and competition from lower-cost producers threaten margins. Domestic oversupply has forced consolidation, and some companies have struggled to achieve profitability.

    Still, Canada’s reputation for quality and compliance continues to differentiate its products in medical markets, where safety standards outweigh price alone.

    As more countries legalize medical cannabis and explore recreational frameworks, Canada’s model is increasingly viewed as a template. Its blend of strict regulation, public health safeguards, and export-oriented production has demonstrated a legal cannabis market can generate jobs, tax revenue, and global trade opportunities.

    For now, Canada remains the world’s cannabis superpower — not only cultivating the crop, but exporting the rules, standards, and economic playbook that may define the industry’s future.

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    Terry Hacienda

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  • Eighth Iron Is Bringing Cannabis Into Golf Culture

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    And 8th Iron is already teed up.

    Golf has always been a slow-burn sport. Long walks. Long pauses. Long conversations stretching from the first tee to the final putt. It’s a game built on rhythm and temperament, where one bad swing can hijack the next five holes if you let your head spiral.

    That’s exactly why cannabis has been quietly riding shotgun in carts for years, even when plenty of clubs still treat it like a dirty secret. Not everyone is chasing a party round. A lot of golfers are chasing calm: looser shoulders, fewer swing thoughts, more patience when the game punches back.

    Dominic DeNucci is building a brand around that overlap. Through 8th Iron Golf Club, he’s betting that cannabis doesn’t disrupt golf culture — it sharpens it.

    Dominic DeNucci Didn’t Grow Up In Golf

    DeNucci didn’t come up through country club junior programs. He grew up playing baseball and football. Golf came later.

    Cannabis didn’t.

    By his late teens, DeNucci was already deep into cultivation, scaling grow setups, and learning the plant beyond just smoking it. He moved into solventless work, including rosin production, where patience and precision matter as much as starting material. That discipline—steady hands, emotional control, attention to detail—would later translate to the course.

    Golf hit him in 2020 and stuck. Within a year, he was competing in money games. In less than two years of playing, DeNucci had become a golf professional—a rare timeline in a sport where most players grind for a decade just to feel competent.

    That matters. 8th Iron doesn’t read like a novelty because DeNucci didn’t borrow golf aesthetics. He earned his place inside the culture. He understands etiquette, the ego, and the unwritten rules. including where cannabis still makes people uncomfortable.

    When he decided to build a club around that overlap, the name came naturally. The 8-iron is one of the most dependable clubs in the bag. It’s versatile, steady, and reliable. Pair that with the familiar “eighth,” and the wink is obvious.

    But the deeper meaning isn’t just wordplay. It’s normalization. Cannabis and golf don’t have to be enemies. The crossover doesn’t have to feel rebellious or disruptive. It can be functional, rooted in respect for the game rather than shock value.

    The goal isn’t to get obliterated mid-round. It’s to get out of your own head.

    Why Golf And Cannabis Actually Work Together

    If you had to design a sport that naturally pairs with cannabis, you’d end up with something that looks a lot like golf.

    It’s outdoors. You’re moving, but you’re not sprinting. There’s space between shots offering time to breathe, reset, and let the last mistake go. Even on a packed Saturday, golf gives you pockets of quiet that most sports don’t.

    Then there’s the mental battle.

    Golf is a slow-motion argument with yourself. The swing is technical, sure. But the bigger fight is emotional—not spiraling after a chunked wedge, not carrying frustration to the next tee box, not letting ego pick the wrong club.

    For many players, cannabis can help smooth those edges. Used responsibly and where permitted, it’s less about “getting lit” and more about lowering the internal volume. Fewer intrusive swing thoughts. Less tension in the shoulders. More presence over the ball.

    Golf punishes extremes. Consistency wins. That overlap of composure over chaos is the thesis behind 8th Iron.

    Legalization doesn’t automatically equal acceptance. DeNucci learned that while planning his first major on-course event in October 2024. Momentum built quickly. Social media lit up. Sponsors showed interest.

    Three weeks before the event, the host course pulled out.

    The concerns were predictable: neighbors, members, optics. The assumption that a cannabis-friendly tournament meant chaos. DeNucci argues the opposite. In his experience, alcohol-based tournaments are more likely to bring reckless behavior. Cannabis crowds tend to show up calmer and more focused on the round itself.

    He scrambled for a replacement venue. Most courses said no. One didn’t: Cross Creek in Temecula.

    The last-minute pivot improved the day. The more secluded setting meant fewer outside complaints and a better atmosphere for what the event was actually meant to be—community-driven, controlled, and centered on golf.

    The proof-of-concept landed.

    8th Iron events aren’t stiff brand activations with step-and-repeat banners and forced sponsor mentions.

    They feel like a round with friends — just scaled up.

    Cannabis brands and golf brands share the same space. Players show up solo and leave with new connections by the 18th green. That dynamic is already built into golf culture. DeNucci is simply removing the tension around something many players were quietly doing anyway.

    Etiquette still matters. Respect still matters. The score still matters.

    The cannabis isn’t there to hijack the day. It’s there to smooth it.

    Las Vegas, Live Music, and “Get High Shoot Low”

    The next expansion takes 8th Iron out of state and into Las Vegas, partnering with Fortunate Youth for a two-day crossover experience: golf first, live music second.

    On April 3, the 8th Iron experience hits the Las Vegas Country Club. On April 4, Fortunate Youth performs at Area 15.

    The brand tagline says it plainly: “Get High, Shoot Low.”

    The meaning isn’t complicated. Even if you’re consuming, you’re still there to compete with yourself. You still want to post a number you’re proud of.

    The high isn’t the destination. The low score is.

    Building Products For The Rhythm Of A Round

    DeNucci isn’t interested in slapping a golf label on generic flower.

    He’s building toward cannabis products designed around how golfers actually experience a round. One concept he’s floated is the “Player Per-Fore-Mance” pack—four joints mapped to four familiar emotional checkpoints: first-tee nerves, a blowup hole, fading focus, mental fatigue.

    The intention isn’t excess. It’s pacing. Golf rewards steadiness. The idea is to match product to moment so the round doesn’t unravel. It’s cannabis framed as performance temperament, not rebellion.

    The Bigger Picture

    Golf and cannabis make sense for the same reason golf works at all: time.

    The sport gives you room to reset. Room to socialize. Room to be present. Add cannabis—responsibly and legally—and you reduce the emotional volatility that ruins rounds.

    That’s the lane DeNucci is carving out with 8th Iron Golf Club.

    Not shock value. Not stoner cosplay. Not anti-golf posturing.

    Just a simple thesis: if the game is about rhythm, patience, and composure, why wouldn’t you use tools that help you access those states?

    Cannabis isn’t crashing the clubhouse.

    It’s already on the course.

    Photos courtesy of Dominic De Nucci

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    Kyle Rosner

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  • Australia – Victorian closed-track driving trial delayed to 2027 | Cannabis Law Report

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    Really ….!! Victorian closed-track driving trial delayed to 2027

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    Sean Hocking

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  • Neon Lychee Strain Feminized Seeds I Vibrnt Sativa Dominant Hybrid

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    About CropKingSeeds

    Established in 2005, Crop King Seeds has been perfecting the genetics of the cannabis plant for medical and commercial grower seeking maximum results in THC levels and harvest size.
    From classic strains to new age hybrids, our seeds are ideal for beginners and advanced growers wanting the best from the crop.

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    Alex Bench

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  • Radioactive Honey Strain Feminized Seeds I Powefully Balanced Hybrid

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    About CropKingSeeds

    Established in 2005, Crop King Seeds has been perfecting the genetics of the cannabis plant for medical and commercial grower seeking maximum results in THC levels and harvest size.
    From classic strains to new age hybrids, our seeds are ideal for beginners and advanced growers wanting the best from the crop.

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    Alex Bench

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  • Turbo Jack Strain Feminized Seeds I High-power Sative Dominant

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    About CropKingSeeds

    Established in 2005, Crop King Seeds has been perfecting the genetics of the cannabis plant for medical and commercial grower seeking maximum results in THC levels and harvest size.
    From classic strains to new age hybrids, our seeds are ideal for beginners and advanced growers wanting the best from the crop.

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    Alex Bench

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  • Why Economists Can’t Understand Why Kids Get High: The Tax Deterrence Delusion

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    The Tax Deterrence Delusion: Why Economists Don’t Understand Why Kids Get High

    There’s a special kind of academic hubris that emerges when economists try to solve social problems without ever talking to the humans involved. It’s the same energy that brought us “rational actor theory” and other beautiful mathematical models that work perfectly on paper and fail spectacularly in reality.

    Enter a recent study from the Learned Societies Trust that asks: “Can taxation be used to effectively limit young people’s use of legalized marijuana?”

    The research, conducted by Michelle Sovinsky, observes that young people tend to use marijuana, alcohol, and cigarettes in combination. The conclusion? If we increase taxes on alcohol and cigarettes, we can reduce marijuana use among youth.

    It’s elegant. It’s data-driven. It’s peer-reviewed.

    And it completely misses the point.

    The Research: What They Found (And What They Missed)

    Sovinsky’s work identifies something legitimately interesting: marijuana consumption among young people correlates strongly with alcohol and cigarette use. The substances appear to be economic complements—when consumption of one goes up, consumption of the others tends to follow.

    From this observation, the researchers theorize that taxation policy targeting alcohol and cigarettes could indirectly reduce marijuana use. Since these substances are consumed together, making alcohol and cigarettes more expensive through taxation should reduce overall consumption of the “bundle.”

    The methodology is sound. The statistics check out. The policy recommendations flow logically from the data.

    But here’s what the study doesn’t do: actually ask young people why they use these substances together.

    Instead of sitting down with actual consumers and understanding their motivations, the research treats human behavior as a purely economic optimization problem—as if teenagers are running cost-benefit analyses before deciding whether to get fucked up on a Friday night.

    They’re analyzing the chemical interactions, the economic elasticities, the cross-price effects. They’re building beautiful regression models.

    And they’re completely ignoring drug synergy, user psychology, and the actual reasons young people want to alter their consciousness in the first place.

    The Real Reason: Drug Stacks and Getting Properly Fucked Up

    If these researchers had spent an evening with a group of teenagers who actually use these substances—maybe even shared a bong rip to establish trust—they would learn something fundamental that doesn’t show up in their econometric models:

    Young people aren’t using alcohol, tobacco, and cannabis together by accident. They’re deliberately combining them for specific psychoactive effects.

    Welcome to the world of “drug stacks.”

    Any experienced psychonaut understands that when you’re playing with the neurochemical settings on your consciousness, you need to know your uppers and downers, your stimulants and depressants, and how they interact synergistically.

    The Tobacco Component: Anxiety Management Theater

    Tobacco serves a specific function in this ecosystem. It’s the socially accepted (if frowned upon) baseline anxiety management tool.

    Nicotine creates a rapid dopamine cycle—the cigarette every 30-45 minutes for moderate smokers, every 10-20 minutes for heavy smokers, every 5-10 minutes for chain smokers. The frequency correlates directly with the level of chaos and anxiety in someone’s life.

    Here’s the paradox nobody wants to acknowledge: roughly 95% of the anxiety a smoker experiences is generated by the addiction itself. We attribute the relief to the cigarette without realizing we were only that stressed because we were craving the cigarette.

    I know this intimately. I used to smoke. I understand the psychology from the inside.

    The chaos in one’s life typically indicates the degree of reliance on the substance. But the substance isn’t solving the underlying problem—it’s creating a dependency loop that mimics anxiety management while actually generating most of the anxiety.

    The Alcohol-Cannabis Combo: Engineering Oblivion

    Then there’s the beer-and-weed combination. Less commonly hard liquor and weed, though depending on the evening’s objective, either works.

    These substances pair together to create a specific experience: alcohol provides body intoxication and dissociation, while cannabis allows you to “ride the wave” and intensify the perceptual distortion.

    It’s a thick, grounded, almost narcotic feeling. Some would call it a “crossfade.” Veterans of the combination know exactly the state I’m describing.

    One might reasonably ask: “Why would anyone deliberately create such a potion of oblivion?”

    The answer, from any teenager at the prime of rebellion, is simple and honest:

    “To get fucked up.”

    The Motivations Nobody’s Asking About

    Here’s what the taxation research fundamentally misses: you cannot understand substance use patterns without understanding user motivations.

    Why do young people want to get fucked up? Let’s consider what we’re asking teenagers to be sober for:

    • Boredom: A life structured around standardized testing, social media dopamine cycles, and economic precarity.

    • Trauma: Whether personal, familial, or collective.

    • Social Media-Induced Anxiety: The constant performance of identity, the comparison trap, the algorithmic manipulation of mood and attention.

    • Global Existential Dread: Climate catastrophe, economic collapse, endless wars, political dysfunction.

    • The Latest Revelation: That some of your political leaders might be cannibalistic pedophiles (at least some of them), and nobody’s going to jail for it.

    You’re at a stage of life where you’re piecing together your identity, trying to figure out your place in a world that seems increasingly hostile to your future. Then you discover these magic potions that can alter your reality, make the unbearable bearable, and create moments of genuine connection and joy in a society optimized for alienation.

    And scientists ask: “What’s the relationship between the drugs?” and “If we tax this, can we deter that?”

    The relationship isn’t chemical—it’s motivational.

    The substances are tools. The goal is escape, connection, exploration, or simply making Friday night more interesting than doom-scrolling TikTok.

    The Psychonaut Perspective: Intentional Consciousness Alteration

    Let me put this in terms that might scandalize the academic reviewers but will resonate with anyone who’s actually explored altered states:

    If you want a cosmically orgasmic experience, pair MDMA with LSD and have sex with someone you love. It’s an easy recipe if you follow the golden rules of set and setting, know what you’re taking, dose appropriately, and are educated about the experience.

    I’m not recommending this to teenagers. I’m illustrating a point: humans have been deliberately combining psychoactive substances for specific effects for thousands of years. This isn’t aberrant behavior—it’s sophisticated pharmacological experimentation, albeit often conducted without proper education or harm reduction infrastructure.

    Young people aren’t passively consuming whatever’s available and happening to use multiple substances. They’re actively curating experiences based on desired effects.

    You want energy and social connection? Alcohol and stimulants.

    You want introspection and sensory enhancement? Cannabis and psychedelics.

    You want to numb out and forget? Alcohol and depressants.

    You want to maintain baseline function while managing anxiety? Nicotine as a background process.

    These aren’t random combinations driven by price elasticity. These are intentional drug stacks designed for specific outcomes.

    The Substitution Effect Nobody Wants to Talk About

    Here’s where the taxation strategy doesn’t just fail—it actively creates harm.

    When you make certain substances too expensive or inaccessible for young people, they don’t just shrug and decide to stay sober. They find alternatives. And those alternatives are often far more dangerous than what you were trying to prevent.

    Let me give you some historical examples that should terrify anyone advocating for simple prohibition-through-pricing:

    The Codeine Crisis: A Cautionary Tale from the 1980s

    During the heavy anti-cannabis crackdowns of the 1980s and early 1990s, when “Just Say No” was policy and marijuana was being demonized as a gateway drug, something interesting happened: codeine cough syrup became a recreational drug of choice among young people.

    “Lean,” “purple drank,” “sizzurp”—whatever you want to call it—became popular precisely because cannabis was too risky to obtain. Kids couldn’t get weed without facing serious legal consequences, so they raided medicine cabinets and pharmacies for over-the-counter medications containing codeine and promethazine.

    The result? A wave of opioid dependency, respiratory depression, and deaths that could have been avoided if these kids had just been smoking joints instead.

    We traded a relatively safe plant for a genuinely dangerous opioid. And we called it drug policy.

    Spice, K2, and Synthetic Cannabinoids: The Monster We Created

    The most damning example of substitution harm is the synthetic cannabinoid epidemic.

    When states started cracking down on marijuana in the 2000s—random drug testing for employment, zero-tolerance policies in schools, harsh criminal penalties—chemists started creating synthetic cannabinoids that could evade drug tests and legal restrictions.

    Spice. K2. “Legal weed.”

    These substances were marketed as safe alternatives to cannabis. They were sold in gas stations and head shops. And they were infinitely more dangerous than the plant they were designed to replace.

    Synthetic cannabinoids have caused:

    Real cannabis has caused none of these things. Zero deaths. Ever. In thousands of years of human use.

    But we made natural cannabis illegal, expensive, and risky to obtain—so the market responded by creating chemical alternatives that could kill you.

    This is what happens when you focus on controlling behavior instead of understanding motivation.

    The Bath Salts Phenomenon

    When traditional stimulants became harder to access or test for, synthetic cathinones (“bath salts”) filled the gap. The results were catastrophic: extreme psychosis, violent behavior, and medical emergencies that made headlines worldwide.

    Again, these substances emerged not because people wanted something more dangerous, but because the safer alternatives were made inaccessible through prohibition and economic barriers.

    The Fentanyl Crisis: The Logical Endpoint

    The ultimate expression of prohibition-driven substitution is the current fentanyl crisis.

    When prescription opioids became harder to obtain through regulatory crackdowns, users didn’t stop using opioids—they turned to street heroin. When heroin supplies became unreliable, dealers started cutting their product with fentanyl because it’s cheaper and more potent.

    Now we have a situation where people seeking pain relief or recreational euphoria are playing Russian roulette with powder that can kill them with a dose measured in micrograms.

    The war on drugs didn’t reduce drug use—it just made drug use exponentially more deadly.

    The Lesser of Two Evils Calculation

    This brings us to an uncomfortable but necessary conversation: sometimes harm reduction requires accepting the lesser of two evils.

    Would you rather have teenagers:

    • Smoking a joint that makes them giggly and hungry, or

    • Smoking K2 that sends them to the emergency room with seizures?

    Would you rather have young adults:

    • Drinking beer and smoking weed at a party, or

    • Taking mystery pills from the internet that might contain anything from MDMA to fentanyl to rat poison?

    Would you rather have people managing pain with:

    • Cannabis that has been used safely for millennia, or

    • Prescription opioids that have killed over 500,000 Americans in two decades?

    The answer should be obvious. But prohibition advocates and taxation enthusiasts refuse to engage with this calculus because it requires admitting that access to safer substances actually reduces harm compared to prohibition.

    This is the fundamental flaw in the “tax it until they can’t afford it” strategy. You’re not eliminating demand—you’re just forcing people toward more dangerous alternatives.

    Why Motivation Matters More Than Price

    The substitution effect demonstrates why understanding motivation is infinitely more important than trying to control behavior through economic disincentives.

    If a young person is seeking altered consciousness because they’re dealing with:

    • Untreated anxiety or depression

    • Trauma from abuse or neglect

    • Social isolation and lack of meaningful connection

    • Existential dread about their future

    • Simple curiosity about altered states

    …then making cannabis more expensive doesn’t address any of those underlying drivers. It just forces them to find alternative solutions.

    And when the safer alternatives are expensive or inaccessible, people turn to whatever is available—regardless of the risk profile.

    The motivation to alter consciousness doesn’t disappear when you raise prices. It just gets channeled into more dangerous pathways.

    This is why the entire framework of deterrence through taxation is fundamentally flawed. It assumes that substance use is driven primarily by availability and cost, when in reality it’s driven by much deeper psychological, social, and spiritual needs.

    The Taxation Solution: Elegant But Insufficient (And Potentially Dangerous)

    Now, to be fair to Sovinsky’s research: analyzing taxation as a policy tool is valuable. There’s genuine utility in understanding cross-price elasticities and how economic incentives shape consumption patterns.

    If we’re going to allow these substances to be legal and commercially available, taxation is one of several levers we can pull to influence behavior—particularly among young people who have limited discretionary income.

    The research shows that increasing taxes on alcohol and cigarettes would likely reduce consumption of the “bundle” including marijuana. That’s useful data for policymakers.

    But here’s what taxation alone cannot do:

    It cannot address the underlying motivations that drive young people to seek altered states in the first place.

    You can make substances more expensive. You can create economic barriers. You can try to price people out of consumption.

    But if the fundamental reasons for use remain unchanged—if we’re still offering young people a world of boredom, anxiety, trauma, and existential dread with no meaningful alternatives—they’ll find ways to get what they need.

    They’ll pool resources. They’ll substitute with cheaper (often more dangerous) alternatives. They’ll turn to unregulated black markets. They’ll synthesize new compounds in underground labs. They’ll find creative workarounds because the motivation is strong enough to overcome economic barriers.

    And those workarounds will almost certainly be more dangerous than the substances you were trying to make inaccessible.

    The Alternative Framework: Age-Based Progressive Taxation

    If we’re going to use taxation as a deterrence mechanism, here’s a more sophisticated approach than simple across-the-board increases:

    Implement age-based progressive taxation that decreases as cognitive development completes.

    Make alcohol, tobacco, and cannabis significantly more expensive for purchasers under 25—the age at which the prefrontal cortex fully develops and risk assessment capabilities mature. As users age out of the highest-risk developmental window, the tax burden decreases until it caps at the standard rate at age 25.

    This approach:

    • Creates economic deterrence during the most vulnerable developmental period

    • Acknowledges that adult use carries different risks than adolescent use

    • Avoids punishing responsible adult consumption to prevent youth use

    • Provides a clear incentive structure tied to developmental biology

    But even this more nuanced approach is insufficient if we’re not simultaneously:

    • Ensuring that safer substances remain more accessible than dangerous alternatives

    • Addressing the motivational drivers of substance use

    • Providing comprehensive harm reduction education

    Without those components, you’re just creating market conditions for the next synthetic cannabinoid epidemic.

    What Actually Works: Education Over Punishment

    Here’s the uncomfortable truth that prohibition advocates don’t want to hear:

    We haven’t given young people a good enough reason NOT to do drugs.

    And I don’t mean “Just Say No” sloganeering or DARE programs that have been proven to increase drug use. I mean genuine, comprehensive, reality-based drug education that treats young people like intelligent humans capable of making informed decisions.

    Imagine if instead of hysterical prohibition messaging, we taught young people:

    • How different substances actually work: Mechanisms of action, neurochemistry, tolerance development, addiction pathways.

    • Harm reduction principles: How to recognize dangerous situations, how to dose safely, how to identify adulterants, when to seek help.

    • The importance of set and setting: How context, mindset, and environment shape experiences.

    • How to recognize problematic use patterns: The difference between experimentation, regular use, and dependency.

    • The substitution risk: Why synthetic alternatives are almost always more dangerous than natural substances, and how prohibition creates market conditions for dangerous innovations.

    • Alternatives for achieving desired states: Meditation, exercise, breathwork, community connection, creative expression.

    • The neuroscience of adolescent development: Why the teenage brain is particularly vulnerable and how to make informed decisions during this critical window.

    This isn’t hypothetical. Countries that have implemented comprehensive drug education programs—treating substances as a public health issue rather than a criminal justice problem—have seen lower rates of problematic use, fewer overdoses, and better outcomes across the board.

    Portugal decriminalized all drugs in 2001 and invested the money saved from enforcement into treatment and education. The results? Dramatic reductions in drug-related deaths, HIV infections, and problematic use. Importantly, people didn’t substitute toward more dangerous alternatives—they had access to safer options and harm reduction services.

    The Netherlands has provided reality-based drug education for decades. Dutch youth have among the lowest rates of cannabis use in Europe despite easy availability. They also haven’t seen the synthetic cannabinoid epidemics that plagued countries with stricter prohibition.

    Switzerland’s heroin-assisted treatment program reduced crime, improved health outcomes, and didn’t increase use rates. By providing access to pharmaceutical-grade opioids under medical supervision, they eliminated the substitution toward fentanyl-laced street drugs that’s killing tens of thousands of Americans annually.

    Education and harm reduction work better than punishment and deterrence. The evidence is overwhelming.

    And crucially, they work better at preventing the substitution effect that makes prohibition-through-taxation so dangerous.

    The Research Gap: Talk to the Fucking Users

    Here’s my challenge to Michelle Sovinsky and every other researcher trying to understand youth substance use:

    Before you build your next econometric model, sit down with actual users and ask them why.

    Not in a clinical setting. Not through surveys designed by academics. Actually spend time in the environments where these substances are consumed. Listen to the stories. Understand the motivations. Learn what people are actually seeking when they combine these substances.

    You’ll get more valuable data from a three-hour conversation with a group of stoners than from a thousand regression analyses.

    You’ll learn that the relationship between substances isn’t about chemical interaction—it’s about intentional experience design.

    You’ll discover that taxation might influence purchasing decisions at the margins, but it can’t address the fundamental human need to occasionally alter consciousness, especially when sober reality offers limited hope, meaning, or joy.

    You’ll understand that young people aren’t passive victims of availability—they’re active agents making choices (sometimes wise, sometimes reckless) in pursuit of specific goals.

    And most importantly, you’ll learn that when you make the safer options inaccessible, people don’t stop seeking altered states—they just find more dangerous ways to achieve them.

    The Sticky Bottom Line

    Can taxation be used to limit young people’s use of marijuana, alcohol, and cigarettes? Sure. Higher prices reduce consumption at the population level. That’s basic economics.

    But if that’s where our policy thinking stops—if we think we can tax our way out of youth substance use without addressing underlying motivations or considering substitution effects—we’re not just setting ourselves up for failure. We’re actively creating conditions for the next public health crisis.

    Every major drug epidemic in recent history has been driven by prohibition and access restrictions forcing people toward more dangerous alternatives:

    • Cannabis prohibition created the synthetic cannabinoid market

    • Prescription opioid crackdowns created the fentanyl crisis

    • Alcohol prohibition created a methanol poisoning epidemic

    • Stimulant restrictions created the bath salts phenomenon

    The pattern is clear: when you restrict access to relatively safe substances through prohibition or prohibitive taxation, people substitute toward more dangerous alternatives.

    Sovinsky’s research is valuable. Understanding cross-price elasticities matters. Taxation should be part of a comprehensive policy framework.

    But it cannot be the primary tool. Not when the real drivers of youth substance use are:

    • A society that offers young people anxiety, precarity, and existential dread

    • An education system that doesn’t teach harm reduction or realistic drug information

    • A culture that demonizes altered states while offering no meaningful alternatives

    • Economic conditions that leave young people with limited prospects and abundant stress

    Tax cigarettes all you want. Triple the price of alcohol. Make marijuana expensive enough that teenagers think twice.

    But understand that you’re playing with fire. Because when you make cannabis too expensive or inaccessible, you’re not preventing teenagers from getting high—you’re just ensuring that when they do, they’re using something far more dangerous.

    Maybe instead of asking “how can we make drugs more expensive?” we should ask “how can we ensure that people seeking altered consciousness have access to the safest possible options, combined with the education to use them responsibly?”

    That’s harm reduction. Everything else is just prohibition with extra steps.

    And prohibition has a body count that speaks for itself.

    Reference

    Sovinsky, M. (2024). “Can taxation be used to effectively limit young people’s use of legalized marijuana?” Learned Societies Trust. https://lt.org/publication-plus/can-taxation-be-used-effectively-limit-young-peoples-use-legalized-marijuana/

     

    TEENS ARE ALL GETTING HIGH? YES OR NO, READ ON…

    THE KIDS WILL ALL BE GETTING HIGH NOT TRUE

    TEENS WILL ALL BE GETTING HIGH – REEFER MADNESS MYTH BUSTED

     

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  • Jamaica Brings It On With Bob Marley-Inspired Jerseys for 2026 FIFA World Cup | High Times

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    Jamaica’s national team has decided that if it’s going to fight for a spot on the road to the 2026 World Cup, it will do so with a strong sense of identity. According to ESPN, the team unveiled its new Adidas jerseys—both the home and away versions—in collaboration with the Bob Marley Foundation, in a move that brings together soccer, culture, and music.

    The launch is part of a broader collection that includes match apparel, lifestyle clothing, and accessories inspired by the musician’s legacy, created with access to the artist’s visual and wardrobe archives.

    The main design draws on the classic yellow of the Jamaican flag and adds details that directly reference reggae’s visual universe: red, green, and black stripes, textures reminiscent of knitted garments and woven pieces, and nods to the ’70s aesthetic associated with Marley. In addition, the jersey also features  direct references to the musician’s style, integrating cultural elements into the athletic design.

    The alternate jersey, meanwhile, features a black base with graphics inspired by sound waves, records, and the island’s musical culture, reinforcing the link between soccer and Jamaica’s sonic heritage.

    The idea is clear: for the jersey to represent not just a team, but an entire culture, incorporating subtle nods to the musician’s visual archives and global influence.

    Both kits include references to the Tuff Gong label and the slogan Football is Freedom, developed with the foundation serving as the project’s conceptual centerpiece.

    According to the official statement, the creative concept aims to frame soccer as a form of cultural expression and freedom, aligned with Marley’s artistic and social vision.

    That said, the launch goes beyond the sporting arena: the collection includes fashion pieces and products inspired by photographs and archival materials from the artist, positioning the project as much a cultural initiative as a soccer one.

    The collaboration fits into a growing trend in international soccer, where uniforms are becoming tools for storytelling and the construction of national identity through design.

    Besides, the connection between Marley and soccer is not merely symbolic: it’s well documented that the musician was passionate about the sport and played frequently, even during tours, reinforcing the cultural coherence of this tribute.

    A Launch Framed by Sporting Stakes

    The new kits arrive at a key moment for the Reggae Boyz, who are aiming to qualify for the 2026 World Cup after decades away from the sport’s biggest stage.

    Jamaica has only played in one World Cup, in France 1998, giving this new cycle added symbolic weight. Now, the team will have to navigate the qualification rounds and potential playoffs to secure a place in the tournament.

    More than just a jersey, the collection positions itself as a bridge between sport, music, and the creative industries, reinforcing the Jamaican national team’s cultural presence on the global stage.

    Now the challenge is on the field: the Reggae Boyz still need to get through the playoffs to secure a spot in the World Cup, something they haven’t achieved in over 20 years. But if they do, they already have a kit that promises to stand out as much as their style of play.

    Cover photo created with AI.

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    Camila Berriex

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  • Hiring in Cannabis Is Broken. High Times Has a Better Way. | High Times

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    Cannabis companies are drowning in applicants and starving for clarity. High Times Recruiting adds a simple layer that makes the first round faster, more human and easier to get right.

    Cannabis companies do not struggle to find applicants. They struggle to quickly spot who is actually a fit. The industry moves fast, runs on thin teams and still has to operate inside a regulatory box that does not care how understaffed you are. When a role opens up, hiring becomes a second job, and it usually lands on the same people who are already running ops, sales, compliance, cultivation schedules and inventory headaches.

    That is why the first interview has become the bottleneck. Not because interviews are bad, but because the first round is often just sorting. You are trying to confirm basics: can this person communicate clearly, do they understand the pace, are they professional, do they stay steady when things get hectic? A resume rarely answers those questions. It can suggest experience, but it cannot show you how someone shows up.

    High Times Recruiting is built around a simple premise: let hiring managers see candidates as people before they spend time scheduling calls. The service sends applicants with both a resume and a short, one way video introduction, usually two to four minutes. The goal is a faster read on communication, presence and role fit, so your live interviews are reserved for the candidates you actually want to meet.

    More details are available at hightimesrecruiting.com.

    The frustrating part is that most hiring managers already know quickly whether a conversation is going anywhere. The issue is that you still spend the time anyway. You stay on the call, you ask the polite questions, you take the notes, you try to be fair, and then you hang up and move to the next one. That is not a hiring strategy. That is a time tax.

    The model is designed for cannabis roles across the supply chain, including retail, cultivation, manufacturing, distribution and brands. It also leans into something traditional recruiting often misses. Cannabis is not just another industry category. Compliance, workflow pressure and culture are real filters here. You can have someone who looks perfect on paper but has never operated inside a regulated store, never worked a harvest schedule, never handled the pace of a scaling brand team, or simply cannot communicate in a way that keeps things steady when the day gets chaotic. The earlier you identify that, the less time you waste.

    Operationally, the system plugs into major job marketplaces, including Indeed and LinkedIn, and turns inbound interest into a curated batch you can review quickly. Each candidate includes a resume and a brief video intro. You review, pick your favorites, then move them into live interviews. High Times Recruiting says it delivers the first batch of qualified candidates within 72 hours and that the average time to hire can be about two weeks once the pipeline is moving.

    The pricing is also structured differently from traditional recruiting. Instead of taking a percentage of salary, the model is a flat fee per successful placement, with payment only when a hire is made. The current fee is $2,500 per placement, plus job post boosts that typically run $500 to $1,000, depending on the role and visibility needs. In a market where traditional recruiters often take 20% to 25% of annual salary, a flat fee approach aims to make recruiting feel more like a predictable operating cost and less like a gamble.

    At its core, this is a bet on time. If you can sort faster, you can hire faster. If you hire faster, you do not drag a team through months of being short-staffed. And in cannabis, that gap is where compliance slips, customers notice, production schedules drift and good people burn out.

    Learn more at hightimesrecruiting.com.

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    High Times

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  • Article: The methamphetamine industry is metastasizing in response to the Taliban drugs ban | Cannabis Law Report

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    The methamphetamine economy is adapting in response to the Taliban’s continued efforts to curb production and trade in Afghanistan. While the industry maintains substantial productive capacity in Afghanistan, it operates at a much smaller scale than in the past. More importantly, the Taliban’s actions to curb the methamphetamine industry in Afghanistan are having a direct impact on the country’s neighbours. Balochistan province in Pakistan appears to be especially vulnerable to widespread drugs production given its permissive environment, the prevalence of armed groups, and a skilled Afghan work force that can easily move across porous borders. Far from being eliminated, the methamphetamine industry is metastasizing in response to the Taliban drugs ban and embedding in the restive tri-border area between Afghanistan, Pakistan and Iran, where it will be particularly difficult to tackle.

    The Taliban continue to suppress the production of methamphetamine in Afghanistan, raising transaction costs and reducing the incomes of those involved. Evidence points to a reduction in operational capacity, with smaller ephedrine and methamphetamine labs and a reduction in both the frequency and the amounts produced (see Figure 1). Lower production in turn has led to reduced demand for the raw input ephedra from the central highlands, which has also become increasingly difficult to harvest due to the Taliban drugs ban and increased vigilance on the roads. The increased risks and costs of production combined with reduced orders for Afghan methamphetamine and falling prices, have reduced both profitability and the incomes of those at each stage of the ephedra-ephedrine-methamphetamine value chain (see Figure 2).       

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    Sean Hocking

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  • Texas CBP officers intercept $6.8M of cocaine hidden in fresh flower shipment | Cannabis Law Report

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    • CBP officers seized $6.8 million worth of cocaine hidden inside a shipment of roses at the Laredo Port of Entry.

    • The drugs, weighing approximately 516 pounds, were discovered in a tractor-trailer following a canine and imaging inspection.

    • Homeland Security Investigations has taken over the case; it remains unclear if any arrests have been made.

    LAREDO, Texas – U.S. Customs and Border Protection officers at the Laredo Port of Entry seized more than $6.8 million worth of cocaine hidden within a shipment of fresh flowers earlier this week, authorities announced Saturday.

    190,000 lethal doses found in rose shipment

    What we know

    The seizure happened Tuesday at the World Trade Bridge after a CBP officer referred a tractor-trailer for a secondary inspection. The driver, or the shipping company, officially declared to the government that the truck was carrying nothing but roses and fresh flowers.

    During the search, which included a canine team and a non-intrusive imaging system, officers found 211 packages hidden within the floral shipment. The packages contained approximately 516 pounds of alleged cocaine. Officials state it was enough for about 190,000 lethal doses.

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    Sean Hocking

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  • Thunder Yuzu Venom Strain Feminized Seeds I Heavy-hitting Indica

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    About CropKingSeeds

    Established in 2005, Crop King Seeds has been perfecting the genetics of the cannabis plant for medical and commercial grower seeking maximum results in THC levels and harvest size.
    From classic strains to new age hybrids, our seeds are ideal for beginners and advanced growers wanting the best from the crop.

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    Alex Bench

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  • Press Release: “Compass Pathways today announced statistically significant positive results in two pivotal Phase 3 trials evaluating COMP360” | Cannabis Law Report

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    Press Release

    Compass Pathways today announced statistically significant positive results in two pivotal Phase 3 trials evaluating COMP360 – a synthetic, proprietary formulation of psilocybin – in treatment-resistant depression (TRD). Notably, COMP360 is the first classic psychedelic to consistently achieve a highly-significant result and clinically meaningful effect, with a well-tolerated safety profile in this historically difficult to treat patient population.

    Details can be found in the press release below, with key findings including:

    • COMP006, which is evaluating two fixed doses of COMP360, achieved its primary endpoint; two doses of COMP360 25mg versus 1mg demonstrated a highly statistically significant and clinically meaningful reduction in symptom severity as measured by MADRS with a mean difference of -3.8 comparing 25mg to 1mg (p<0.001).

    • COMP005 maintained durability of effect at least through week 26 after just one or two doses.

    • Across both trials, COMP360 was found generally safe and well-tolerated, with the vast majority of adverse events being mild to moderate and resolving on the day of treatment.

    This is a remarkable achievement in psychiatry. TRD impacts approximately 4 million patients in the U.S. for whom multiple antidepressants have provided little or no response. There are limited treatment options available and tremendous need.

    Please let me know if you are interested in speaking with Compass leadership and/or a trial investigator who can provide additional context about the significance of these results for patients, the science behind COMP360 and broader implications for mental health care.

    Best,

    Hadley Kerr

    On behalf of Compass Pathways 

    +++

    Compass Pathways Successfully Achieves Primary Endpoint in Second Phase 3 Trial Evaluating COMP360 Psilocybin for Treatment-Resistant Depression

    February 17, 2026

    • Two highly statistically significant positive Phase 3 trials confirm highly differentiated profile for COMP360, demonstrating a level of clinical effect that has historically been extremely difficult to achieve in TRD

    • COMP360 is the first classic psychedelic1 to consistently achieve a highly statistically significant result and clinically meaningful effect, with a generally well-tolerated and safe profile

    • In COMP006, two doses of COMP360 25 mg versus 1 mg demonstrated a highly statistically significant and clinically meaningful reduction in symptom severity as measured by MADRS2 with a mean difference of -3.8 comparing 25 mg to 1 mg (p<0.001)3

    • Clinically meaningful reduction in MADRS (≥ 25%) observed in significant number of participants in 25mg arm of both trials with 25% in COMP005 and 39% in COMP006

    • Statistically significant rapid onset from the day following administration maintained at all measured timepoints through Week 6 in both clinical trials in the 25 mg arm

    • In COMP005, participants who achieved a clinically meaningful reduction in MADRS at Week 6 with COMP360 25 mg maintained durability of effect at least through Week 26 after just one or two doses

    • Across both Phase 3 trials to date, COMP360 is demonstrating a generally well-tolerated and safe profile with no unexpected safety findings

    • Compass has requested a meeting with the FDA to discuss a rolling submission and review and expects to complete an NDA submission in Q4

    • Compass management will host a webinar on February 17th at 8:00 am ET

    LONDON & NEW YORK–(BUSINESS WIRE)– Compass Pathways plc (Nasdaq: CMPS), a biotechnology company dedicated to accelerating patient access to evidence-based innovation, announced today the successful achievement of the primary endpoint in the ongoing Phase 3 COMP006 trial, the second of two Phase 3 trials, which is evaluating two fixed doses of COMP360, a synthetic, proprietary formulation of psilocybin, for treatment-resistant depression (TRD). The primary endpoint was the difference in change from baseline in the Montgomery-Åsberg Depression Rating Scale (MADRS) scores between the 25 mg and 1 mg groups at Week 6. Two fixed doses – administered 3 weeks apart – of COMP360 25 mg versus 1 mg demonstrated a highly statistically significant reduction in symptom severity with a p-value of <0.001 and a clinically meaningful difference of -3.8 points in change at the primary endpoint.

    Across COMP005 and COMP006 to date, COMP360 is demonstrating a generally well-tolerated and safe profile, with treatment-emergent adverse events (TEAEs) being mild or moderate in severity, and the vast majority resolving within 24 hours. The data confirms a statistically significant rapid onset from the day following administration and maintained at all measured timepoints through Week 6 in both clinical trials in the 25 mg arm. COMP005 suggests that participants who demonstrated a clinically meaningful reduction in MADRS maintained durable treatment effect at least through Week 26, after just one or two doses. Retreatment with a second dose was well-tolerated, with a consistent safety profile.

    Compass has submitted a request for a meeting with the U.S. Food and Drug Administration (FDA) to discuss a rolling submission and review.

    “Across three robust, well-designed and well-executed clinical trials involving more than 1,000 participants, we have now demonstrated consistent, highly statistically significant results at the primary endpoint and a clinically meaningful effect. This is a remarkable achievement for the field of psychiatry – especially in the TRD population, where proving benefit has historically been extraordinarily challenging,” said Kabir Nath, Chief Executive Officer at Compass Pathways. “These data strengthen our conviction in the highly differentiated profile for COMP360 and given the urgent need for new treatments in TRD, we are advancing our discussions with the FDA, with the goal of submitting an NDA in Q4 and securing approval.”

    “TRD patients have extremely limited treatment options, and the unmet need remains profound. The promising clinical profile of COMP360 reinforces our belief in its potential to set a new standard of care for this population,” said Dr. Guy Goodwin, Chief Medical Officer at Compass Pathways. “These results redefine rapidity and durability for TRD patients with onset as early as the next day and, for those who respond, effects from just one or two doses lasted at least through 26 weeks, alongside a well-tolerated safety profile. Across the very limited TRD treatment landscape, this potential treatment truly stands out for its extremely rapid and sustained efficacy. We are incredibly grateful to the participants, investigators, and clinical trial staff for their invaluable contributions to our trials and for making this significant progress possible.”

    Key Findings

    Efficacy Profile

    COMP005

    • Primary endpoint of Part A (previously disclosed in June 2025): Single dose of COMP360 25 mg versus placebo with a mean treatment difference of -3.6 points, 95% CI [-5.7, -1.5]; p<0.001 at Week 6 4

    • For participants who had a clinically meaningful reduction in MADRS (≥ 25%), a statistically significant rapid onset from the day following administration was maintained at all measured timepoints through Week 6 in the 25 mg arm

    • 25% of participants in the 25 mg arm achieved a clinically meaningful reduction in MADRS (≥ 25%) at Week 6 with durability lasting out through 26 weeks after just one or two doses of 25 mg

    • Over 40% of those who achieved a clinically meaningful reduction in MADRS but had not remitted by 6 weeks went into remission after the second dose in Part B

    COMP006

    • Primary endpoint of Part A: Two doses of COMP360 25 mg versus 1 mg with a mean treatment difference of -3.8 points, 95% CI [-5.8, -1.8]; p<0.001 at Week 6

    • 39% of participants in the 25 mg arm achieved a clinically meaningful reduction in MADRS (≥ 25%) at Week 6

    • For participants who achieved a clinically meaningful reduction in MADRS (≥ 25%), a statistically significant rapid onset from the day following administration was maintained at all measured timepoints through Week 6 in the 25 mg arm

    • The 26-week data (Part B) from COMP006 is expected in early Q3 2026

    Safety Profile

    The Chair of the independent Data Safety Monitoring Board (DSMB) provided the following statement: “Based on the latest review of this data for the 005 and 006 TRD studies, safety findings are consistent with previous studies of COMP360 and there are no new, unexpected or concerning safety findings. Safety findings are consistent with the known profile of the study drug (a classical psychedelic) and the treatment-resistant depression patient population. From this review of the data, there is no evidence of a clinically meaningful imbalance between treatment arms in suicidality in either study.”5

    COMP005

    In the 25 mg arm, (Part A and B):

    • Most TEAEs occurred on the days of study drug administration (66%), with the vast majority (88%) resolving within a day

    • Most common TEAEs reported were headache, nausea and visual hallucination

    • There were 11 treatment-emergent serious adverse events (SAEs) from 8 participants (5%) overall

    COMP006

    In the 25 mg arm (Part A):

    • Most TEAEs occurred on the days of study drug administration (73%) with the vast majority (83%) resolving within a day

    • Most common TEAEs were headache, nausea, anxiety and visual hallucination

    • There were 6 treatment-emergent serious adverse events (SAEs) from 6 participants (2%) overall

    Across both trials, for the data available to date, the rate for SAE suicidal ideation was less than 1%. There was only one event of SAE suicidal behavior, which occurred in the 1 mg arm in COMP006.

    Live Webcast

    A replay of the webcast will be accessible for 30 days following the event.

    About the COMP360 Phase 3 Program

    The COMP360 program aims to evaluate the safety and efficacy of COMP360 psilocybin, a synthetic, proprietary formulation of psilocybin under investigation for difficult-to-treat mental health conditions. There are two pivotal Phase 3 trials, COMP005 and COMP006, evaluating the efficacy of COMP360 for treatment-resistant depression (TRD).

    The ongoing COMP005 trial is a randomized, double-blind, placebo-controlled study, with 258 dosed participants across the United States and is assessing the efficacy and safety of a single dose of 25 mg COMP360 versus placebo for reducing symptom severity in TRD (COMP360 25 mg: n=171; placebo: n=87).The trial is comprised of three parts: Part A, which was blinded through 6 weeks; Part B, which has recently concluded and was blinded through week 26; and Part C, which contains an open-label treatment part from week 26 to 52.

    The ongoing COMP006 trial, running in parallel to the COMP005 trial, is a randomized, double-blind study with 581 dosed participants across North America and Europe and is comparing the efficacy and safety of two fixed doses, taken three weeks apart, of 25 mg COMP360 to 10 mg COMP360 and 1 mg COMP360 (25 mg: n=296; 10 mg: n=142; 1 mg: n=143). The trial is comprised of three parts: Part A, which has recently concluded and was blinded through 9 weeks, Part B which remains blinded through week 26, and Part C, which contains an open-label treatment part from week 26 to 52.

    About treatment resistant depression (TRD)

    Depression, one of the most common mental health disorders, significantly impacts relationships, work performance, overall quality of life, and is associated with an increased risk of suicide. Major depressive disorder (MDD) has been ranked as the third cause of the burden of disease worldwide in 2008 by the World Health Organization (WHO), which has projected that this disease will rank first by 2030.
    It is estimated that approximately 4 million patients in the U.S. with MDD live with TRD6. TRD is broadly defined as an inadequate response to two or more appropriate courses of approved medications. TRD has a significantly greater impact on individuals compared to MDD, leading to residual symptoms, poorer quality of life, increased comorbidities, higher mortality, and an increased risk of suicide compared to non-treatment resistant MDD.

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    Sean Hocking

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