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Tag: University of Basel

  • Study: U.S. Medical Cannabis Laws Increase Patient’s Mental Health

    Study: U.S. Medical Cannabis Laws Increase Patient’s Mental Health

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    Researchers from the University of Basel in Switzerland recently published a study on April 2 to analyze how medical cannabis legalization in the U.S. has affected the country and its patients’ well-being.

    Entitled “Medical marijuana laws and mental health in the United States,” researchers wanted to determine the effects of medical cannabis policies on patients over time. “The consequences of legal access to medical marijuana for individuals’ well-being are controversially assessed,” researchers wrote. “We contribute to the discussion by evaluating the impact of the introduction of medical marijuana laws across U.S. states on self-reported mental health considering different motives for cannabis consumption.”

    Researchers analyzed the responses of 7.9 million people who participated in phone surveys between 1993-2018. This information was collected through the Behavioral Risk Factor Surveillance System, which focuses on data collection regarding “mental well-being.” In addition to this, researchers also utilized data collected by the National Survey on Drug Use and Health.

    Participants were placed in specific groups, such as those who were “highly likely to abstain from using marijuana, to use marijuana as a recreational drug, or to use it for medical reasons” in order to determine the overall affect of medical cannabis legalization on their mental health. Additionally, researchers took into account the use of cannabis specifically for overall chronic pain.

    Mental health was measured by asking participants to self-assess themselves by recording how many days they encountered mental health problems during the month prior to the assessment.

    Ultimately, researchers found that medical cannabis legalization had no effect on either recreational consumers or youth. “We find weak evidence of positive effects on mental health due to the liberalisation of medical marijuana for the U.S. population overall,” researchers wrote in their conclusion. “While the estimated overall reduction in poor mental health days is not statistically significant, the result still implies an absence of evidence for the critical perspectives that highlight the risk of aggravated mental health problems due to MML [medical marijuana laws] introductions.”

    “Easier access improves the mental health of individuals who use marijuana for medical reasons,” stated a University of Basel press article. “The same applies to people who are very likely to suffer from pain. The study authors estimate that these two groups spend 0.3 days less per month in poor mental health due to the change in the law.”

    Professor Alois Stutzer summarized these findings in his own statement as well. “Overall, our results show that medical cannabis legislation in the USA benefits the people it is intended for without harming other groups,” Stutzer said. He explained that recreational cannabis consumers aren’t worse off after legalization, either, and ultimately there is “a clear relationship between liberalization and mental well-being.”

    Both the U.S. and Switzerland both share a federal government structure. While Stutzer calls the most recent study an “experimental article” because it can help pave the way toward more studies that analyze Switzerland’s future cannabis industry.

    The most recent study only extended to data collected prior to 2018, so it would be interesting to see a future study analyze even more recent data that accompanies the many other states that have legalized medical and/or adult-use cannabis within the past five years.

    Switzerland has been conducting isolated cannabis pilot programs to analyze consumer trends, sales patterns, and more. Recently at the end of March, the first data connected to one of these programs was released.

    The ZüriCan study includes 1,928 people who have been approved to purchase cannabis for the study (a total of 2,100 individuals can participate). The newest data shared that of current participants, 80.7% are men, 18% are women, and 1% are nonbinary people. The demographic disparity was not a surprise, however, as researchers expected there to be a vast difference in gender-related consumers.

    Additionally, researchers found that participants between the ages of 28-32 represented the highest percentage among all age groups (the average age of consumers is currently 35 years old). “Participation in the study seems to be particularly attractive for people who consume frequently,” researchers wrote. “However, people who only use cannabis a few times a month also take part in the study. This will allow us to compare people with different consumption habits in our study.”

    The program data also showed that 6,500 sales have been made so far, with approximately 309 pounds of cannabis sold (individual packs were available only in five gram amounts).

    Tobias Viegener, the head of marketing Cannavigia, a company that is working directly with the Swiss Federal Office on Public Health, told Forbes about the significance of this early data. “The initial data from the ‘ZüriCan’ pilot, published this month, reveals promising insights into the regulated cannabis market’s functionality and its acceptance among participants,” Viegener said. “This level of engagement indicates a positive reception and an effective distribution system, setting a solid foundation for informing future cannabis policy and regulation.”

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    Nicole Potter

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  • Skiing over Christmas holidays no longer guaranteed – even with snow guns

    Skiing over Christmas holidays no longer guaranteed – even with snow guns

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    Newswise — For many people, holidays in the snow are as much a part of the end of the year as Christmas trees and fireworks. As global warming progresses, however, white slopes are becoming increasingly rare. Researchers at the University of Basel have calculated how well one of Switzerland’s largest ski resorts will remain snow reliable with technical snowmaking by the year 2100, and how much water this snow will consume.

    The future for ski sports in Switzerland looks anything but rosy – or rather white. Current climate models predict that there will be more precipitation in winter in the coming decades, but that it will fall as rain instead of snow. Despite this, one investor recently spent several million Swiss francs on expanding the Andermatt-Sedrun-Disentis ski resort. A short-sighted decision they will regret in future?

    A research team led by Dr. Erika Hiltbrunner from the Department of Environmental Sciences at the University of Basel has now calculated the extent to which this ski resort can maintain its economically important Christmas holidays and a ski season of at least 100 days with and without snowmaking. The team collected data on the aspects of the slopes, where and when the snow is produced at the ski resort and with how much water. They then applied the latest climate change scenarios (CH2018) in combination with the SkiSim 2.0 simulation software for projections of snow conditions with and without technical snowmaking. The results of their investigations were recently published in the International Journal of Biometeorology.

    No guarantee of a white Christmas

    According to the results, the use of technical snow can indeed guarantee a 100-day ski season – in the higher parts of the ski resort (at 1,800 meters and above), at least. But business is likely to be tight during the Christmas holidays in coming decades, with the weather often not cold enough at this time and in the weeks before. In the scenario with unabated greenhouse gas emissions, the Sedrun region in particular will no longer be able to offer guaranteed snow over Christmas in the longer term. New snow guns may alleviate the situation to a certain extent, say the researchers, but will not resolve the issue completely.

    “Many people don’t realize that you also need certain weather conditions for snowmaking,” explains Hiltbrunner. “It must not be too warm or too humid, otherwise there will not be enough evaporation cooling for the sprayed water to freeze in the air and come down as snow.” Warm air absorbs more moisture and so, as winters become warmer, it also gets increasingly difficult or impossible to produce snow technically. In other words: “Here, the laws of physics set clear limits for snowmaking.”

    540 million liters

    The skiing will still go on, however, because technical snowmaking at least enables resort operators to keep the higher ski runs open for 100 consecutive days – even up until the end of the century and with climate change continuing unabated. But there is a high price to be paid for this. The researchers’ calculations show that water consumption for snowmaking will increase significantly, by about 80% for the resort as a whole. In an average winter toward the end of the century, consumption would thus amount to about 540 million liters of water, compared with 300 million liters today.

    But this increase in water demand is still relatively moderate compared with other ski resorts, the researchers emphasize. Earlier studies had shown that water consumption for snowmaking in the Scuol ski resort, for example, would increase by a factor of 2.4 to 5, because the area covered with snow there will have to be largely expanded in order to guarantee snow reliability.

    For their analysis, the researchers considered periods of 30 years. However, there are large annual fluctuations: In addition, extreme events are not depicted in the climate scenarios. In the winter of 2017 with low levels of snow, water consumption for snowmaking in one of the three sub-areas of Andermatt-Sedrun-Disentis tripled.

    Conflicts over water use

    Today, some of the water used for snowmaking in the largest sub-area of Andermatt-Sedrun-Disentis comes from the Oberalpsee. A maximum of 200 million liters may be withdrawn annually for this purpose. If climate change continues unabated, this source of water will last until the middle of the century, at which point new sources will have to be exploited. “The Oberalpsee is also used to produce hydroelectric power,” says Dr. Maria Vorkauf, lead author of the study, who now works at the Agroscope research station. “Here, we are likely to see a conflict between the water demands for the ski resort and those for hydropower generation.”

    At first, this ski resort may even benefit from climate change – if lower-lying and smaller ski resorts are obliged to close, tourists will move to larger resorts at higher altitude, one of which is Andermatt-Sedrun-Disentis.

    What is certain is that increased snowmaking will drive up costs and thus also the price of ski holidays. “Sooner or later, people with average incomes will simply no longer be able to afford them,” says Hiltbrunner.

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    University of Basel

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  • Spin correlation between paired electrons demonstrated

    Spin correlation between paired electrons demonstrated

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    Newswise — Physicists at the University of Basel have experimentally demonstrated for the first time that there is a negative correlation between the two spins of an entangled pair of electrons from a superconductor. For their study, the researchers used spin filters made of nanomagnets and quantum dots, as they report in the scientific journal Nature.

    The entanglement between two particles is among those phenomena in quantum physics that are hard to reconcile with everyday experiences. If entangled, certain properties of the two particles are closely linked, even when far apart. Albert Einstein described entanglement as a “spooky action at a distance”. Research on entanglement between light particles (photons) was awarded this year’s Nobel Prize in Physics.

    Two electrons can be entangled as well – for example in their spins. In a superconductor, the electrons form so-called Cooper pairs responsible for the lossless electrical currents and in which the individual spins are entangled.

    For several years, researchers at the Swiss Nanoscience Institute and the Department of Physics at the University of Basel have been able to extract electron pairs from a superconductor and spatially separate the two electrons. This is achieved by means of two quantum dots – nanoelectronic structures connected in parallel, each of which only allows single electrons to pass.

    Opposite electron spins from Cooper pairs

    The team of Prof. Dr. Christian Schönenberger and Dr. Andreas Baumgartner, in collaboration with researchers led by Prof. Dr. Lucia Sorba from the Istituto Nanoscienze-CNR and the Scuola Normale Superiore in Pisa have now been able to experimentally demonstrate what has long been expected theoretically: electrons from a superconductor always emerge in pairs with opposite spins.

    Using an innovative experimental setup, the physicists were able to measure that the spin of one electron points upwards when the other is pointing downwards, and vice versa. “We have thus experimentally proven a negative correlation between the spins of paired electrons,” explains project leader Andreas Baumgartner.

    The researchers achieved this by using a spin filter they developed in their laboratory. Using tiny magnets, they generated individually adjustable magnetic fields in each of the two quantum dots that separate the Cooper pair electrons. Since the spin also determines the magnetic moment of an electron, only one particular type of spin is allowed through at a time.

    “We can adjust both quantum dots so that mainly electrons with a certain spin pass through them,” explains first author Dr. Arunav Bordoloi. “For example, an electron with spin up passes through one quantum dot and an electron with spin down passes through the other quantum dot, or vice versa. If both quantum dots are set to pass only the same spins, the electric currents in both quantum dots are reduced, even though an individual electron may well pass through a single quantum dot.”

    “With this method, we were able to detect such negative correlations between electron spins from a superconductor for the first time,” Andreas Baumgartner concludes. “Our experiments are a first step, but not yet a definitive proof of entangled electron spins, since we cannot set the orientation of the spin filters arbitrarily – but we are working on it.”

    The research, which was recently published in Nature, is considered an important step toward further experimental investigations of quantum mechanical phenomena, such as the entanglement of particles in solids, which is also a key component of quantum computers.

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    University of Basel

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