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Tag: protein

  • Chlorohydrin 3-MCPD in Bragg’s Liquid Aminos | NutritionFacts.org

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    Chlorohydrin contaminates hydrolyzed vegetable protein products and refined oils.

    In 1978, chlorohydrins were found in protein hydrolysates. What does that mean? Proteins can be broken down into amino acids using a chemical process called hydrolysis, and free amino acids (like glutamate) can have taste-enhancing qualities. That’s how inexpensive soy sauce and seasonings like Bragg’s Liquid Aminos are made. This process requires high heat, high pressure, and hydrochloric acid to break apart the protein. The problem is that when any residual fat is exposed to these conditions, it can form toxic compounds called chlorohydrins, which are toxic at least to mice and rats.

    Chlorohydrins like 3-MCPD are considered “a worldwide problem of food chemistry,” but no long-term clinical studies on people have been reported to date. The concern is about the detrimental effects on the kidneys and fertility. In fact, there was a time 3-MCPD was considered as a potential male contraceptive because it could so affect sperm production, but research funding was withdrawn after “unacceptable side effects [were] observed in primates.” Researchers found flaccid testes in rats, which is what they were going for, but it caused neurological scars in monkeys.

    What do you do when there are no studies in humans? How do you set some kind of safety factor? It isn’t easy, but you can take the lowest observed adverse effect level (LOAEL) in animal studies, which, in this case, was kidney damage, add in some kind of fudge factor, and then arrive at an estimated tolerable daily intake (TDI). For 3-MCPD, this means that high-level consumers of soy sauce may exceed the limit. This was based on extraordinarily high contamination levels, though. Since that study, Europe introduced a regulatory limit of 20 parts per billion (ppb) of 3-MCPD in hydrolyzed vegetable protein products like liquid aminos and soy sauce. The U.S. standards are much laxer, though, setting a “guidance level” of up to 50 times more, 1,000 parts per billion.

    I called Bragg’s to see where it fell, and the good news is that it is doing an independent, third-party analysis of its liquid aminos for 3-MCPD. The bad news is that, despite my pleas that it be fully transparent, Bragg’s wouldn’t let me share the results with you. I have seen them, though, but I’m only allowed to confirm they comfortably meet the U.S. standards but fail to meet the European standards.

    This is just the start of the 3-MCPD story, though. A study in Italy tested individuals’ urine for 3-MCPD or its metabolites, and 100% of the people turned up positive, confirming that it’s “a widespread food contaminant.” But 100% of people aren’t consuming soy sauce or liquid aminos every day. Remember, the chemical results from a reaction with residual vegetable oil. When vegetable oil itself is refined, when it’s deodorized and bleached, those conditions also lead to the formation of 3-MCPD.

    Indeed, we’ve known for years that various foods are contaminated. In what kinds of foods have these kinds of chemicals been detected? Well, if they’re in oils and fats, then they’re in greasy foods made from them: margarine, baked goods, pastries, deep-fried foods, fatty snacks like potato and corn chips, as well as infant formula.

    The U.S. Food and Drug Administration’s limit for soy sauce is 1,000 ppb, but donuts can have more than 1,200 ppb, salami more than 1,500 ppb, ham nearly 3,000 ppb, and French fries in excess of 6,000 ppb, as seen here and at 4:03 in my video The Side Effects of 3-MCPD in Bragg’s Liquid Aminos.

    Most of us don’t have to worry about this problem, unless we’re consumers of fried food. Someone weighing about 150 pounds, for example, who eats 116 grams of donuts, would exceed the European Food Safety Authority’s TDI, even if those donuts were the person’s only source of exposure. That’s about two donuts, but the same limit-blowing amount of 3-MCPD could be found in only five French fries.

    Doctor’s Note

    Believe me, I pleaded with the Bragg’s folks over and over. It’s curious to me that Bragg’s allowed me to talk about where its level of 3-MCPD fell compared to the standards but not say the number itself. At least it’s doing third-party testing.

    Learn more about this topic in my video 3-MCPD in Refined Cooking Oils.

    You can also check out Friday Favorites: The Side Effects of 3-MCPD in Bragg’s Liquid Aminos and Refined Cooking Oils.

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    Michael Greger M.D. FACLM

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  • An RD’s Go-To Filling Lunch Recipe + Benefits

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    Whipping up a colorful and delicious lunch salad can be convenient—until you find yourself hungry an hour later. If this experience sounds familiar, just know you’re not alone: Crafting a lunch that’s equally healthy as it is filling is no easy feat. 

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  • Dilly Chicken Salad On Toast Makes An Easy Protein-Packed Lunch

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    Crunchy, salty pickles are an incredible addition to so many meals. The acidity helps cut fattiness, and even a small amount adds so much flavor. Adding fresh dill and briny pickles to chicken salad takes it from ordinary to addictive. There’s just the right amount of crunch from extra veggies (carrots, celery, and the pickles) and a tangy bite from the mustard. I prefer to serve it as an open-face sandwich since you get two sandwiches for the price of one— meaning more delicious bites and more variety.

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  • How AI Helped Me Spot The Real Reason Behind My Afternoon Cravings

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    How to understand your body’s needs without obsessing over it

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  • The Sneaky Reason Your Plant Protein Isn’t As Good As You Think

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    The branched-chain amino acid activates the body’s mTOR pathway1, which controls the anabolic (growth) and catabolic (breakdown) signaling of skeletal muscle. “You can think of the BCAA leucine as a trigger or ‘its go-time’ button for muscle protein synthesis (i.e., the critical cellular process for building muscle),” explains mindbodygreen’s former vice president of scientific affairs, Ashley Jordan Ferira, Ph.D., RDN.

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  • How To Reconnect With Your Hunger Cues & Curb Mindless Snacking

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  • Protein vs. Amino Acid Supplements: Here’s The Difference

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    For the last two years, we’ve seen multiple supplements that were once only found in bodybuilders’ shaker cups make their way into mainstream use. First, it was protein powders, as everyone realized they would benefit from a protein boost. Next was creatine, as people realized this highly researched supplement delivers fitness, recovery, and cognitive benefits to all.* Now, it’s all about amino acids. 

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  • 3 Quick Ways To Ease Jitters From Too Much Caffeine

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  • I’m A Longevity MD: 3 Things I Wish I Did For My Health In My 20s

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  • What You Need To Know About Body Comp & Exercise For Perimenopause

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    Plus, science-backed ways to ease this journey.

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  • 3 Metabolic Benefits Of Eating Whey Protein Powder Daily

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    Only 12% of U.S. adults are considered metabolically healthy. So most of us have some room for improvement when it comes to blood sugar, lipids, and blood pressure. And one (very easy) thing you can do to sway your health for the better is to eat more protein—specifically whey protein powder. 

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  • You Can’t Skip Meals & Expect Gains: Eat More To Build Muscle

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    For years, the health and fitness world has perpetuated the idea that “eating less and exercising more” is the holy grail for achieving a lean, strong physique. Abbie Smith-Ryan, Ph.D., a leading researcher in the field of metabolism, sports nutrition, and exercise performance, is here to tell you that this approach is outdated—and counterproductive.

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  • This Unexpected “Appetizer” Can Help Balance Your Blood Sugar

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    Whey protein is beneficial for more than just muscle gains.

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  • Study Suggests This Is The Ultimate Duo To Combat Inflammaging

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    Aging doesn’t just come with wisdom—it often brings inflammation too. This chronic, low-grade inflammatory state, cleverly dubbed “inflammaging,” is a major driver of age-related diseases, including heart disease, Type 2 diabetes, neurodegeneration, and even cancer.

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  • Skipping Breakfast? Here’s What It’s Really Doing To Your Stress Levels

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    Skipping breakfast might sound like a harmless time-saver, but science is here to serve a wake-up call. Research found that skipping your morning meal could do more than make you a little hangry—it may actually disrupt your cortisol rhythm and elevate blood pressure. 

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  • 5 Must-Have Supplements For Active Women: What To Take & Why

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    Here’s how to fuel your body like a pro.

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  • You Can’t Skip Meals & Expect Gains: Eat More To Build Muscle

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    For years, the health and fitness world has perpetuated the idea that “eating less and exercising more” is the holy grail for achieving a lean, strong physique. Abbie Smith-Ryan, Ph.D., a leading researcher in the field of metabolism, sports nutrition, and exercise performance, is here to tell you that this approach is outdated—and counterproductive.

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  • How Long You Should Wait Between Meals For Optimal Digestion

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    As with many things nutrition-related, sometimes it seems like the guidance around meal timing ping-pongs back and forth between contradictory recommendations. “Eat three square meals a day.” “No, eat six small meals per day.” “Wait several hours between meals.” “Go ahead and graze all day!” It’s enough to make you wonder whether there are any trustworthy parameters around meal timing at all.

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  • Are Doctors Knowledgeable About Nutrition?  | NutritionFacts.org

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    Do you know more about basic nutrition than most doctors?

    “A poor diet now outranks smoking as the leading cause of death globally and in the United States, according to the latest data.” The top killer of Americans is the American diet, as you can see below and at 0:23 in my video How Much Do Doctors Actually Know About Nutrition?.

    If diet is humanity’s number one killer, then, obviously, nutrition is the number one subject taught in medical school, right? Sadly, “medical students around the world [are] poorly trained in nutrition.” It isn’t that medical students aren’t interested in learning about it. In fact, “interest in nutrition was ‘uniformly high’ among medical students,” but medical schools just aren’t teaching it. “Without a solid foundation of clinical nutrition knowledge and skills, physicians worldwide are generally not equipped to even begin to have an informed nutrition conversation with their patients….”

    How bad is it? One study, “Assessing the clinical nutrition knowledge of medical doctors,” found the majority of participants got 70 percent of the questions wrong—and they were multiple choice questions, so they should have gotten about a fifth of them right just by chance. “Wrong answers in the…knowledge test were not limited to difficult or demanding questions” either. For example, less than half of the doctors were able to guess how many calories are in fat, carbohydrates, and protein; only one in ten knew the recommended protein intake; and only about one in three knew what a healthy body mass index (BMI) was. We’re talking about really basic nutrition knowledge.

    Even worse, not only did the majority of medical doctors get a failing grade, but 30 percent of those who failed had “a high self-perception of their CN [clinical nutrition] expertise.” They weren’t only clueless about nutrition; they were clueless that they were clueless about nutrition, a particularly bad combination given that doctors are “trusted and influential sources” of healthy eating advice. “For those consumers who get information from their personal healthcare professional, 78% indicate making a change in their eating habits as a result of those conversations.” So, if the doctor got everything they know from some article in a magazine while waiting in the grocery store checkout aisle, that’s what the patients will be following.

    Of doctors surveyed, “only 25% correctly identified the American Heart Association recommended number of fruit and vegetable servings per day, and fewer still (20%) were aware of the recommended daily added sugar limit for adults.” So how are they going to counsel their patients? And get ready for this: Of the doctors who perceived themselves as having high nutrition knowledge, 93 percent couldn’t answer those two basic multiple-choice questions, as seen here and at 2:39 in my video.

    “Physicians with no genuine expertise in, say, neurosurgery [brain surgery] are neither likely to broadcast detailed opinions on that topic nor to have their ‘expert’ opinions solicited by the media. Most topical domains in medicine enjoy such respect: we defer expert opinion and commentary to actual experts. Not so nutrition, where the common knowledge that physicians are generally ill-trained in this area is conjoined to routine invitations to physicians for their expert opinions on the matter. All too many are willing to provide theirs, absent any basis for actual expertise…” Or worse, they’re “often made on the basis of native bias and personal preference, at times directly tethered to personal gain—such as diet book sales—and so arises yet another ethical challenge.” That’s one of the reasons all the proceeds I receive from my books are donated directly to charity. I don’t want even the appearance of any conflicts of interest.

    “In a culture that routinely fails to distinguish expertise from mere opinion or personal anecdote, we physicians should be doing all we can to establish relevant barriers to entry for expert opinion in this [diet and nutrition], as in all other matters of genuine medical significance.” I mean, we aren’t talking celebrity gossip. Lives are at stake. “Entire industries are devoted to marketing messages that may conspire directly against well-informed medical advice in this area.”

    “Medical education must be brought up to date. For physicians to be ill-trained in the very area most impactful on the rate of premature death at the population level is an absurd anachronism….The mission of medicine is to protect, defend, and advance the human condition. That mission cannot be fulfilled if the diet is neglected.”

    A possible starting place? “Physicians and health care organizations can collectively begin to emphasize their seriousness about nutrition in health care by practicing what they (theoretically) preach. Is it appropriate to serve pizza and soft drinks at a resident conference while bemoaning the high prevalence of obesity and encouraging patients to eat healthier? A similarly poor example exists in medical conferences, including national meetings, where some morning sessions are accompanied by foods such as donuts and sausage.”

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    Michael Greger M.D. FACLM

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