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Tag: nutrition

  • Almond Milk Yogurt: More Nutritious Than Dairy-Based Yogurt

    Almond Milk Yogurt: More Nutritious Than Dairy-Based Yogurt

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    Newswise — AMHERST, Mass. – In a nutritional comparison of plant-based and dairy yogurts, almond milk yogurt came out on top, according to research led by a University of Massachusetts Amherst food science major.

    “Plant-based yogurts overall have less total sugar, less sodium and more fiber than dairy, but they have less protein, calcium and potassium than dairy yogurt,” says lead author Astrid D’Andrea, a graduating senior whose paper was published May 25 in a special issue of the journal Frontiers in Nutrition titled Food of the Future: Meat and Dairy Alternatives. “But when looking at the overall nutrient density, comparing dairy yogurt to plant-based yogurt, with the nutrients that we looked at, almond yogurt has a significantly higher nutrient density than dairy yogurt and all other plant-based yogurts.”

    Working in the lab of senior author Alissa Nolden, a sensory scientist and assistant professor of food science, D’Andrea was interested in comparing the nutritional values of plant-based and dairy yogurts, an area of research she found lacking. Driven by concerns over environmental sustainability and eating less animal-based food products, the plant-based yogurt market is expected to explode from $1.6 billion in 2021 to $6.5 billion in 2030.

    “Plant-based diets are gaining popularity, especially in American culture, but just because it’s plant-based doesn’t mean it’s more nutritious,” says D’Andrea, of Hazlet, N.J., who is heading to graduate school in food science at Penn State. “There has to be specific research that answers that question.”

    D’Andrea collected nutritional information for 612 yogurts, launched between 2016 and 2021, using the Mintel Global New Products Database, accessed through UMass Libraries. She used the Nutrient Rich Foods (NRF) Index, which assigns scores based on the nutrient density of foods. “This allowed us to compare the nutritional density of the yogurts based on nutrients to encourage (protein, fiber, calcium, iron, potassium, vitamin D) and nutrients to limit (saturated fat, total sugar, sodium),” D’Andrea writes in her paper.

    The researchers chose the NRF model based on the nutritional benefits of dairy yogurt, which provides a complete protein, something plant-based products are unable to do.

    Of the 612 yogurts analyzed, 159 were full-fat dairy, 303 were low- and nonfat dairy, 61 were coconut, 44 were almond, 30 were cashew and 15 were oat. The researchers used the NRF Index to rank the yogurts from the highest to lowest nutrient density: almond, oat, low- and nonfat dairy, full-fat dairy, cashew and coconut.

    D’Andrea attributed the high scores of almond and oat yogurts to their low levels of total sugar, sodium and saturated fat. She and Nolden say the study’s findings can inform the food industry on ways to improve the formulation and nutritional composition of plant-based yogurts.

    One option the researchers offer is creating a hybrid yogurt that is both plant- and dairy-based. This will add protein, vitamin B12 and calcium while still minimizing total sugar, sodium and saturated fat.

    “Going from dairy all the way to plant-based is a big change,” Nolden says. “There are changes in the nutritional profile, and there’s change in the sensory profile, which might prevent consumers from trying it.”

    In fact, a recent study conducted in the Nolden lab led by former UMass Amherst visiting researcher Maija Greis investigated consumer acceptance of blended plant-based and dairy yogurt and found that people preferred the blended yogurt over the plant-based one.

    “Blending provides advantages,” Nolden says. “It provides a complete protein, and the dairy part helps to form the gelling structure within the yogurt that so far we are unable to replicate in a plant-based system.”

    The UMass Amherst team says further research is warranted, based on their findings that suggest a way to maximize the nutrition and functional characteristics of yogurt.

    “If we can blend plant-based and dairy yogurt, we can achieve a desirable sensory profile, a potentially better nutritional profile and have a smaller impact on the environment,” Nolden says.

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    University of Massachusetts Amherst

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  • Natto: A Stress-Busting Food

    Natto: A Stress-Busting Food

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    Newswise — Health is wealth as the saying goes and new research now shows that it is possible to have a healthy, less stressed society through familiar and inexpensive foods. One such food might be the Japanese natto which is made from softened soybeans that have been boiled or steamed and fermented with a bacteria called Bacillus subtilis var. nattoBacillus subtilis var. natto is found in soil, plants, animals, and the human stomach and intestines. Most of the natto consumed in Japan is made from the Miyagino strain.

    A research group led by Professor Eriko Kage-Nakadai at the Graduate School of Human Life and Ecology, Osaka Metropolitan University, examined the effects of Bacillus subtilis var. natto consumption on the lifespan of the host using Caenorhabditis elegans worms. The researchers found that Caenorhabditis elegans fed Bacillus subtilis var. natto had a significantly longer lifespan than those fed the standard diet, and further elucidated that the p38 MAPK pathway and insulin/IGF-1-like signaling pathway, which are known to be involved in innate immunity and lifespan, were involved in the lifespan-enhancing effects of Bacillus subtilis var. natto. They also examined stress tolerance, which has been shown to have a correlation with longevity, and found that resistance to UV light and oxidative stress is enhanced.

    Professor Nakadai concluded, “For the first time, we were able to demonstrate the possibility of lifespan-extending effects of Caenorhabditis elegans through the ingestion of Bacillus subtilis var. natto. We hope that future experiments on mammals and epidemiological studies will help to realize a healthy and longer-living society if we can apply this research to humans.”

    The research results were published online in the Journal of Applied Microbiology on April 20, 2023.

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    Osaka Metropolitan University

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  • Kite surfing, ice baths and 8-mile morning runs: How some CEOs stay in shape

    Kite surfing, ice baths and 8-mile morning runs: How some CEOs stay in shape

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    What is it about CEOs and their intense — and often oddball — workout routines?

    These days, some top corporate honchos take their exercise rituals to extremes. Consider Damola Adamolekun, chief executive officer of restaurant chain P.F. Chang’s, who recently told Fortune magazine that he wakes up each day at 4:30 a.m. and runs seven to eight miles. He explained that the routine stimulates his nervous system and sets the tone for the day ahead. “You’ll feel better the whole day; you’ll be smarter, you’ll be sharper, you’ll be more energetic,” he said.

    Adamolekun is in good company when it comes to training hard. Here are how five other executives work up a sweat and aim to stay healthy.

    Jack Dorsey, head of Block and co-founder of Twitter, walks an hour and 15 minutes every day.


    AFP via Getty Images

    Jack Dorsey

    The Twitter co-founder, who now heads the tech conglomerate Block
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    does it all: two-hour meditations, fasting — he has said he eats only once a day during the week and has almost no food on the weekends — and alternating saunas and ice baths. But he’s no gym rat: Dorsey gets his primary exercise by walking an hour and 15 minutes every day. “I might look a little bit more like I’m jogging than I’m walking. It’s refreshing … It’s just this one of those take-back moments where you’re like, ‘Wow, I’m alive!’” he once observed.

    Meta’s Mark Zuckerberg takes his dog for frequent runs — good exercise for both him and his pooch.


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    Mark Zuckerberg

    The Meta Platforms
    META,
    +1.09%

    chief isn’t one to get up at the crack of dawn, according to GQ, but he still runs three mornings a week. “I also try to take my dog running whenever I can, which has the added bonus of being hilarious because that’s basically like seeing a mop run,” he told GQ. As for diet, he once was said to experiment with an eating plan that involved only devouring animals he had killed himself — including chickens, goats and pigs. But he also apparently skips meals — or at least he said as much in a 2021 Facebook post. “Do you ever get so excited about what you’re working on that you forget to eat meals?” he asked.

    Richard Branson takes off on another kite-surfing adventure.


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    Richard Branson

    Kite surfing, anyone? The founder of the Virgin Group swears by it as one of his favorite ways to stay fit, according to Men’s Health. He once even kite surfed across the English Channel. His other activities include tennis and biking. He’ll work with a trainer if he’s on the road, but otherwise he likes to exercise outdoors on his private island in the British Virgin Islands. “I just want to be sure that when I’m 150, my body still looks as good as it is today,” said Branson, who is now 72.

    Palantir Technologies CEO Alex Karp works out by cross-country skiing — and says the key is to take it as slowly as possible to build your “cardio base.”


    Getty Images

    Alex Karp

    The head of software company Palantir Technologies takes advantage of the fact that he lives near the White Mountains of New Hampshire to have a regular cross-country skiing routine. Key to his approach, he told Axios, is taking it slow on the snow. “To run like a deer, you have to spend 90% of your time running like a snail,” he explained, adding that his unhurried pace “builds a cardio base.” He also includes tai chi and stretching to his routine. But he isn’t too fussy about his diet. “If I’m traveling and someone has a really nice Danish, I enjoy every minute of eating it,” he said.

    Martha Stewart is one of the cover models for Sport Illustrated’s new swimsuit issue.


    Sports Illustrated

    Martha Stewart

    The 81-year-old lifestyle entrepreneur and founder of Martha Stewart Living Omnimedia has been in the spotlight for her recent cover appearance on Sports Illustrated’s swimsuit issue. So what does she do to stay in shape for beach season? Stewart swears by Pilates, according to various media reports. And she rides horses. She has also said she doesn’t smoke, eats very well and every morning drinks a glass of “green juice” made with pears, cucumbers, celery stalks, parsley, fresh ginger and two oranges (complete with peels), a recipe she calls “so spectacular.”

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  • The Bulk Milk Solution: Chef Ann Foundation Launches National Program to Help Schools Reduce Food Waste

    The Bulk Milk Solution: Chef Ann Foundation Launches National Program to Help Schools Reduce Food Waste

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    Milk is one of the biggest sources of food waste at schools across the country. Schools serve approximately 275 million single-serve cartons of milk to K-12 students every school day, resulting in a staggering amount of waste. Switching to serving milk from a bulk dispenser into reusable cups is a simple way for schools to drastically cut waste. 

    To help schools transition to using bulk milk dispensers, Chef Ann Foundation launched Bulk Milk. Through this new program, school districts anywhere in the U.S. can apply now for a grant to receive nearly all of the equipment, materials, and training needed to implement a bulk milk serving system. 

    Early adopters of bulk milk dispensers have seen impressive results. Canby School District in Oregon eliminated approximately 50% of its school lunch waste volume. Meanwhile, Bluestone Elementary in Virginia saw a 91% reduction of milk packaging waste volume when it moved to using a bulk milk dispenser. 

    Waste also comes from milk students don’t drink. Approximately 45 million gallons of milk get poured down drains at schools each year. Wasted milk means the environmental and financial resources that went into producing, transporting, cooling, and storing the milk are wasted, too. By switching to a bulk milk system, which allows students to pour themselves only the amount of milk they want to drink, schools could save 30 pounds of carbon dioxide per student annually — the equivalent of taking 145,000 gas-powered vehicles off the road.

    Further, schools using bulk milk dispensers found that students are consuming more milk, supporting improved nutrition. “Since switching to bulk milk, we’ve noticed increases in consumption. The kids love the taste and enjoy drinking from a cup instead of a carton,” said Rita Denton, director of student nutrition at Mansfield Independent School District in Texas. 

    Denton’s experience is backed by a wider study on school milk waste and consumption. By better regulating temperature, bulk milk dispensers help improve taste. “Dispenser milk is always cold and delicious. The equipment keeps it fresh, so kids like it better,” said Chef Ann Cooper, founder of the Chef Ann Foundation and former director of food services at Boulder Valley School District in Colorado.

    Districts that have switched to bulk milk dispensers have also experienced financial benefits. “We are seeing savings from purchasing bulk milk instead of cartons of $285 per week at our pilot school,” said Denton. Savings like these could help schools switch from purchasing conventional milk to organic milk, ideally produced locally and from cows raised on pasture.

    School districts interested in learning more about Chef Ann Foundation’s Bulk Milk grant program can register for a free informational webinar happening May 31 at 9 a.m. Mountain Time. Grant applications are due July 31. 

    The Bulk Milk grant is open to school districts across the country thanks to support from the Posner Foundation.

    Source: Chef Ann Foundation

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  • Urine use for sustainable food systems in sub-Saharan cities

    Urine use for sustainable food systems in sub-Saharan cities

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    Newswise — Installing urine collection systems in sub-Saharan city regions would make those conurbations more sustainable. This was demonstrated by a study by four researchers from CIRAD, IRD, Boubakar Bâ University of Tillaberi (Niger) and Joseph Ki-Zerbo University, Ouagadougou (Burkina Faso), published on 3 May 2023 in the journal Regional Environmental Change. For their study, the researchers analysed nitrogen flows in waste in two sub-Saharan cities: Maradi (Niger) and Ouagadougou. The study was a first, and showed that urine was the main source of nitrogen losses. Collecting that urine could provide valuable fertilizer suitable for local agricultural use, and thus serve to make city region food systems more sustainable.

    Current urban development trajectories in sub-Saharan Africa are not sustainable. Fast-growing cities constitute nutrient sinks relying on nutrient-poor hinterlands. Those sinks, and the degradation and draining of nutrients in hinterlands, have significant environmental and health impacts. This runs counter to The UN Sustainable Development Goal 11, which aims to “make cities and human settlements inclusive, safe, resilient and sustainable”.

    To give the authorities a cross-sectoral view of a city’s nutrient sink status, the researchers identified and analysed a range of waste flows. Their approach distinguished four nested spatial levels: the urban area; the potential territorial recycling system; the country and the international level. Based on that analysis, the researchers focused on the origin and fate of those nutrient-containing waste flows. The method was applied to nitrogen in Maradi and Ouagadougou, to determine whether and to what extent those city regions could progress towards sustainable urban food systems. The fact of focusing on the nitrogen in waste rather than on waste flows themselves enabled a systemic understanding useful to the local authorities.

    The study showed that Maradi was a nitrogen sink, albeit at the heart of a still relatively sustainable urban food system. However, it could well evolve towards a situation similar to that of Ouagadougou: a large nitrogen sink with no significant city-hinterland recycling. Although of contrasting size, currently around 400 000 and 2 800 000 inhabitants respectively, these two cities evolve in highly similar biophysical, climatic, agricultural and socioeconomic settings. Their respective results may thus be considered an approximate illustration of a development trajectory.

    The study provided the first overview of waste-contained nitrogen flows in sub-Saharan cities. Existing reports so far provided only partial, sectoral assessments, focusing either on waste management, on sanitation, or on agriculture, while this study showed that nitrogen losses through sanitation and waste management largely exceeded other waste-contained nitrogen flows in these cities. Urine is therefore the main source of nitrogen loss. Urine collection initiatives to enable its use as a fertilizer would make urban systems more independent and resilient. This would improve regional food provision and reduce sanitation-induced urban water pollution, making urban systems more sustainable. The researchers consider that addressing the potential for urine recycling would be a worthwhile follow-up to this study.

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    Institut de Recherche pour le Developpement (IRD)

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  • New peanut-allergy skin patch shows promise: ‘This would fill a huge unmet need’

    New peanut-allergy skin patch shows promise: ‘This would fill a huge unmet need’

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    An experimental skin patch may soon allow increased protection for toddlers who are allergic to peanuts, according to a new study published in the New England Journal of Medicine.

    The patch, named Viaskin, is coated with a small amount of peanut protein that is absorbed into the skin and would offer some protection against an accidental peanut ingestion that so many parents fear at birthday parties, in school cafeterias or on play dates.

    If additional testing pans out, “this would fill a huge unmet need,” Dr. Matthew Greenhawt, an allergist at Children’s Hospital Colorado who contributed to the study, told the Associated Press.

    There is no cure for food allergies. The number of Americans who are allergic to peanuts is estimated at 6.1 million, according to FARE, one of the largest private funding sources for food-allergy research.

    About 2% of U.S. children are allergic to peanuts, some so severely than even a tiny exposure can cause a life-threatening reaction. Their immune systems overreact to peanut-containing foods, triggering an inflammatory cascade that causes hives, wheezing or worse. Some youngsters outgrow the allergy, but most must avoid peanuts for life and carry rescue medicine to stave off a severe reaction if they accidentally ingest an allergen.

    In 2020, the Food and Drug Administration approved the first treatment to induce tolerance to peanuts — an “oral immunotherapy” named Palforzia that children ages 4 to 17 consume daily to keep up the protection.

    The new study, which featured work from dozens of medical professionals in the U.S. and abroad, took samples from 362 toddlers with a peanut allergy. The toddlers were initially tested to see how high a dose of peanut protein they could tolerate. Then they were randomly assigned to use the Viaskin patch or a lookalike placebo patch every day.

    After a year of treatment, they were tested again, and about two-thirds of the toddlers who used the Viaskin patch could safely ingest more peanut protein safely. One in three of the toddlers who were given the dummy patch also could safely ingest more peanuts, but Greenhawt said it’s likely those children had outgrown the allergy.

    Deaths from allergic reactions to any food numbed a few hundred per year, according to the CDC. But each year there are about 200,000 emergency-room visits caused by allergic reactions to food.

    The Associated Press contributed to this report.

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  • German lawmakers mull creating first citizen assembly

    German lawmakers mull creating first citizen assembly

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    German lawmakers are considering whether to create the country’s first “citizen assembly” to advise parliament on the issue of food and nutrition

    BERLIN — German lawmakers considered Wednesday whether to create the country’s first “citizen assembly’” to advise parliament on the issue of food and nutrition.

    Germany’s three governing parties back the idea of appointing consultative bodies made up of members of the public selected through a lottery system who would discuss specific topics and provide nonbinding feedback to legislators. But opposition parties have rejected the idea, warning that such citizen assemblies risk undermining the primacy of parliament in Germany’s political system.

    Baerbel Bas, the speaker of the lower house, or Bundestag, said that she views such bodies as a “bridge between citizens and politicians that can provide a fresh perspective and create new confidence in established institutions.”

    “Everyone should be able to have a say,” Bas told daily Passauer Neue Presse. “We want to better reflect the diversity in our society.”

    Environmental activists from the group Last Generation have campaigned for the creation of a citizen assembly to address issues surrounding climate change. However, the group argues that proposals drawn up by such a body should at the very least result in bills that lawmakers would then vote on.

    Similar efforts to create citizen assemblies have taken place in other European countries such as Spain, Finland, Austria, Britain and Ireland.

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  • Mental illness may put people under 40 at a greater chance of heart attack and stroke | CNN

    Mental illness may put people under 40 at a greater chance of heart attack and stroke | CNN

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    CNN
     — 

    Adults in their 20s and 30s with mental disorders have a higher chance of having a heart attack or stroke, according to a new study.

    The study published Monday in the European Journal of Preventive Cardiology looked at the health data of more than 6.5 million people through the Korean National Health Insurance Service database.

    The people included in the new study ranged in age from 20 to 39 and underwent health examinations between 2009 and 2012. Their health was monitored until December 2018 for new onset heart attacks and stroke.

    About 13% of participants had some type of mental disorder — which included insomnia, anxiety, depression, somatoform disorder, post-traumatic stress disorder, substance use disorder, eating disorders, bipolar disorder, schizophrenia or a personality disorder, according to the study.

    Those people younger than 40 with a mental disorder were 58% more likely to have a heart attack and 42% more likely to have a stroke than those with no disorder, the study found.

    “We have known for some time that mental health and physical health are linked, but what I find surprising about these findings is that these links were observable at such a young age,” said Dr. Katherine Ehrlich, an associate professor of behavioral and brain sciences at the University of Georgia. Ehrlich was not involved in the research.

    Coronary arterial disease and heart attacks are rare before the age of 40, so a study as large as this one was needed to see the relationship between mental health and such an unusual occurrence in young people, she said.

    Ehrlich said she would like to know more about the physical activity and diets of the people involved to understand better if those factors have an influence on the relationship between mental health conditions and heart attack and stroke.

    “For example, if you are chronically depressed, you may struggle to maintain a healthy diet and get adequate physical activity, which might in turn increase your risk for cardiac events over time,” she said.

    But the increased risk could not be attributed to lifestyle differences alone, as the authors controlled for factors including age, sex, high blood pressure, diabetes, high cholesterol, metabolic syndrome, chronic kidney disease, smoking, alcohol, physical activity and income, the study said.

    That doesn’t mean lifestyle should be ignored, however, said study author Dr. Eue-Keun Choi, a professor of internal medicine at Seoul National University College of Medicine in South Korea.

    “While lifestyle behaviours did not explain the excess cardiovascular risk, this does not mean that healthier habits would not improve prognosis,” Choi said in a statement. “Lifestyle modification should therefore be recommended to young adults with mental disorders to boost heart health.”

    One in eight people between ages 20 and 39 studied had some sort of mental illness, meaning a substantial number of people could be predisposed to heart attack and stroke, study author Dr. Chan Soon Park, a researcher at Seoul National University Hospital in South Korea said in a statement.

    That could point to a greater need for managing psychological conditions and monitoring heart health in those at risk, Park added.

    “If we can reduce the number of people living with chronic mental illness, we may find secondary benefits in future years regarding the number of people managing cardiac-related conditions,” Ehrlich said.

    It is important to note that the findings do not show that mental illness causes heart attacks or stroke, she added. But the research does indicate a risk factor to watch out for.

    There may be benefit in preventive measures to minimize risks, Ehrlich said, which can include maintaining a healthy diet and incorporating physical activity.

    Choi recommends that people with mental health conditions receive regular checkups as well.

    These findings may also emphasize the importance of addressing loneliness, she added.

    “Many individuals with mental illness suffer from social isolation and loneliness, and for years researchers have been sounding the alarm that loneliness is detrimental for physical health,” Ehrlich said.

    “Efforts to improve social connectedness among young people may be critical to addressing the rising rates of cardiometabolic conditions in adulthood,” she added.

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  • Behavior Patterns of People Who Achieve Clinically Significant Weight Loss

    Behavior Patterns of People Who Achieve Clinically Significant Weight Loss

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    Newswise — COLUMBUS, Ohio – A new study analyzing data on over 20,000 U.S. adults links a healthier diet and increased exercise to weight loss that reduces heart disease risk – while associating skipping meals and taking prescription diet pills with minimal weight loss, weight maintenance or weight gain. 

    For many in the study sample, however, losing a “clinically significant” 5% of their body weight did not eliminate their risk factors for cardiovascular disease, results showed. In fact, the average composite score on eight risk factors for heart disease was the same across the entirety of the study population – regardless of reported weight changes, up or down.

    The study is the first to compare weight-loss strategies and results in the context of the American Heart Association’s “Life’s Essential 8,” a checklist promoting heart disease risk reduction through the pursuit of recommended metrics for body weight, blood pressure, cholesterol, blood sugar, smoking, physical activity, diet and sleep. The AHA first defined a construct of cardiovascular health with “Life’s Simple 7” metrics in 2010, and updated the recommendations to the “Life’s Essential 8” in June 2022. 

    The Ohio State University researchers found that overall, U.S. adults had an average score of 60 out of 100 on the eight measures – suggesting there is plenty of room for improvement even among those whose diet and exercise behaviors helped move the needle on some metrics. 

    “The Life’s Essential 8 is a valuable tool that provides the core components for cardiovascular health, many of which are modifiable through behavior change,” said senior study author Colleen Spees, associate professor of medical dietetics in the School of Health and Rehabilitation Sciences at Ohio State.  

    “Based on the findings in this study, we have a lot of work to do as a country,” she said. “Even though there were significant differences on several parameters between the groups, the fact remains that as a whole, adults in this country are not adopting the Life’s Essential 8 behaviors that are directly correlated with heart health.”

    The research was published recently in the Journal of the American Heart Association

    Data for the analysis came from 20,305 U.S. adults aged 19 or older (average age of 47) who participated in the National Health and Nutrition Examination Survey (NHANES) between 2007 and 2016. Participants reported their smoking status, physical activity, average hours of sleep per night, weight history and weight loss strategy, and what they had eaten in the previous 24 hours. Health exams and lab tests measured their body mass index, blood pressure, LDL (bad) cholesterol and blood glucose. 

    The Ohio State researchers used the data to determine individuals’ values for Life’s Essential 8 metrics and assessed their diet quality according to the Healthy Eating Index, which gauges adherence to U.S. Dietary Guidelines for Americans

    Within the sample, 17,465 individuals had lost less than 5% of their body weight, maintained their weight or gained weight in the past year. The other 2,840 reported intentional loss of at least 5% of their body weight in the same time frame.

    “Clinically significant weight loss results in improvements in some health indices,” Spees said. “People should feel hopeful in knowing that losing just 5% of their body weight is meaningful in terms of clinical improvements. This is not a huge weight loss. It’s achievable for most, and I would hope that incentives people instead of being paralyzed with a fear of failure.” 

    In this study, adults with clinically significant weight loss reported higher diet quality, particularly with better scores on intakes of protein, refined grains and added sugar, as well as more moderate and vigorous physical activity and lower LDL cholesterol than the group without clinically significant weight loss. On the other hand, the weight-loss group also had a higher average BMI and HbA1c blood sugar measure and fewer hours of sleep – all metrics that would bring down their composite Life’s Essential 8 score.

    A greater proportion of people who did not lose at least 5% of their weight reported skipping meals or using prescription diet pills as weight-loss strategies. Additional strategies reported by this group included low-carb and liquid diets, taking laxatives or vomiting, and smoking. 

    “We saw that people are still gravitating to non-evidence-based approaches for weight loss, which are not sustainable. What is sustainable is changing behaviors and eating patterns,” Spees said. 

    With federal data estimating that more than 85% of the adult U.S. population will be overweight or obese by 2030 (compared to the current rate of 73%), Spees said that to fend off related increases in heart disease and other health problems, a paradigm shift toward prevention is in order.

    “We absolutely need to be moving toward prevention of disease versus waiting until people are diagnosed with a disease. This becomes quite overwhelming, and individuals may feel it’s too late at that point,” she said. 

    One idea to consider, she said, would be prescriptions for regular visits with registered dietitians trained in behavior change, complete with insurance reimbursement – similar to physical therapy. 

    “We have fantastic research, we have incredible educators,” she said. “What we don’t have is policy that promotes optimal health across the lifespan, from pregnancy through older adulthood.”

    Co-authors of the study included first author Emily Hill (supported by a National Center for Advancing Clinical Sciences fellowship), Lauren Cubellis, Randell Wexler and Christopher Taylor.

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    Ohio State University

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  • Ideal liquids for antioxidant-rich spinach smooth

    Ideal liquids for antioxidant-rich spinach smooth

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    Newswise — Different market products give very different results when it comes to liberating the antioxidant lutein from spinach in smoothies. Researchers at Linköping University, Sweden, have examined 14 common dairy and plant-based products and found that only four of these increased lutein liberation. Compared to water, some drinks had a negative effect on the lutein content in spinach smoothies.  

    Most people know that spinach is good for your health. One substance found in, for instance, spinach and kale is lutein. Several experimental studies have shown that lutein can suppress processes linked to inflammation, and there is now ample research indicating that chronic low-grade inflammation is an important risk factor in cardiovascular disease. 

    “Lutein is a bio-active compound. We have studied lutein in a similar way to studying a pharmaceutical drug. In this study, we looked at lutein liberation from fresh spinach,” says Rosanna Chung, assistant professor in the Department of Health, Medicine and Caring Sciences at Linköping University, who led the study published in Nutrients.

    As our bodies cannot produce lutein, the researchers behind the study were interested to find out how to optimise lutein intake from foods. The research group previously showed that preparation methods where the spinach is heated break down some of the lutein, whereas mixing it into a smoothie makes more lutein available for absorption. 

    The type of liquid used in the smoothie can also affect lutein content. As lutein dissolves in fat but not in water, it needs gastric juice and/or other food components to be liberated from the plant material and absorbed by our intestines. The researchers suspected that some components in our food, such as fat, carbohydrates, proteins and fibres, can affect the amount of lutein available for absorption. The effect of products such as yoghurt may also differ due to fermentation. However, products widely available on the market are rarely examined in scientific studies.   

    The researchers have examined the effects of various products available from food shops on the amount of lutein liberated in smoothies. Both dairy and plant-based liquids were tested.

    The researchers blended spinach with the various products. They then used a method simulating human digestion in the gastrointestinal tract, by adding digestive enzymes. Finally, the amount of lutein available for the body to absorb in smoothies made with various products was compared to that in smoothies made with just water. 

    “We could see that only 4 of the 14 examined products increased the liberation of lutein from spinach compared to water. Cow’s milk with a high fat content as well as coconut milk improved lutein liberation. Yoghurt, however, which is regarded as comparable to cow’s milk and is often used in cafés and similar, did not show particularly good results,” says Rosanna Chung.

    The fact that yoghurt is not that good at liberating lutein may have to do with the fermentation process. It also turned out that plant-based drinks, often made from nuts, legumes or oats, showed significantly different results.

    “Plant-based liquids have become increasingly common in smoothies. We saw that soymilk was actually less effective than water when it comes to liberating lutein in spinach smoothies. In other words, soymilk had a negative effect on lutein liberation in our study,” says Jan Neelissen, doctorate student and one of the researchers behind the study. 

    The other plant-based products in the study did not affect lutein liberation compared to water. As a general piece of information, smoothies should be consumed as soon as possible, because lutein breaks down quickly.

    It is important to note that whereas the results from this study indicate how much lutein is available for the body to absorb, no conclusions can be drawn as to how much lutein is actually absorbed. Therefore, the researchers will be conducting a human study in which they will measure the amount of lutein absorbed from smoothies made with different products.

    The study was supported by project grants from the Dr P Håkanssons Stiftelse, the Swedish Heart-Lung Foundation and the Swedish Research Council, and was carried out in collaboration with researchers at the Occupational and Environmental Medicine Unit of the University Hospital in Linköping.

    Article: The Effects of Dairy and Plant-Based Liquid Components on Lutein Liberation in Spinach Smoothies, Jan Neelissen, Per Leanderson, Lena Jonasson och Rosanna W. S. Chung, (2023), Nutrients, published online on 2 February 2023, Vol. 15, 779, doi: 10.3390/nu15030779

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  • How to Achieve Superhuman Levels of Focus with Nutritional Psychology | Entrepreneur

    How to Achieve Superhuman Levels of Focus with Nutritional Psychology | Entrepreneur

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    Ben Angel, bestselling author of Unstoppable (Entrepreneur Press® 2018), CLICK, Sleeping Your Way to The Top in Business, and Flee 9-5, is Australia’s leading marketing authority. Founder of benangel.co, a site dedicated to providing entrepreneurs advanced online marketing courses and education, Ben provides easy-to-apply and even easier-to-understand strategies for reaching new customers with ease.

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  • Should we all be switching to the ice-cream diet? Here’s the scoop on a controversial idea.

    Should we all be switching to the ice-cream diet? Here’s the scoop on a controversial idea.

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    Put aside for a moment all that nutritional advice about eating fruits and vegetables, whole grains and lean proteins. Could one key to good health actually be a diet rich in … ice cream?

    That’s the tantalizing question raised by a new story in the Atlantic, which states, “Studies show a mysterious health benefit to ice cream. Scientists don’t want to talk about it.”

    The…

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  • Refined carbs and red meat driving global rise in type 2 diabetes, study says | CNN

    Refined carbs and red meat driving global rise in type 2 diabetes, study says | CNN

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    Editor’s Note: Sign up for CNN’s Eat, But Better: Mediterranean Style. Our eight-part guide shows you a delicious expert-backed eating lifestyle that will boost your health for life.



    CNN
     — 

    Gobbling up too many refined wheat and rice products, along with eating too few whole grains, is fueling the growth of new cases of type 2 diabetes worldwide, according to a new study that models data through 2018.

    “Our study suggests poor carbohydrate quality is a leading driver of diet-attributable type 2 diabetes globally,” says senior author Dr. Dariush Mozaffarian, a professor of nutrition at Tufts University and professor of medicine at Tufts School of Medicine in Boston, in a statement.

    Another key factor: People are eating far too much red and processed meats, such as bacon, sausage, salami and the like, the study said. Those three factors — eating too few whole grains and too many processed grains and meats — were the primary drivers of over 14 million new cases of type 2 diabetes in 2018, according to the study, which was published Monday in the journal Nature Medicine.

    In fact, the study estimated 7 out of 10 cases of type 2 diabetes worldwide in 2018 were linked to poor food choices.

    “These new findings reveal critical areas for national and global focus to improve nutrition and reduce devastating burdens of diabetes,” said Mozaffarian, who is also the editor in chief of the Tufts Health & Nutrition Letter.

    Mozaffarian and his team developed a research model of dietary intake between 1990 and 2018 and applied it to 184 countries. Compared with 1990, there were 8.6 million more cases of type 2 diabetes due to poor diet in 2018, the study found.

    Researchers found eating too many unhealthy foods was more of a driver of type 2 diabetes on a global level than a lack of eating wholesome foods, especially for men compared with women, younger compared to older adults, and in urban versus rural residents.

    Over 60% of the total global diet-attributable cases of the disease were due to excess intake of just six harmful dietary habits: eating too much refined rice, wheat and potatoes; too many processed and unprocessed red meats; and drinking too many sugar-sweetened beverages and fruit juice.

    Inadequate intake of five protective dietary factors — fruits, nonstarchy vegetables, nuts, seeds, whole grains and yogurt — was responsible for just over 39% of the new cases.

    People in Poland and Russia, where diets tend to focus on potatoes and red and processed meat, and other countries in Eastern and Central Europe as well as Central Asia, had the highest percentage of new type 2 diabetes cases linked to diet.

    Colombia, Mexico and other countries in Latin America and the Caribbean also had high numbers of new cases, which researchers said could be due to a reliance on sugary drinks and processed meat, as well as a low intake of whole grains.

    “Our modeling approach does not prove causation, and our findings should be considered as estimates of risk,” the authors wrote.

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  • Study Links Poor Diet to 14 Million Cases of Type 2 Diabetes Globally

    Study Links Poor Diet to 14 Million Cases of Type 2 Diabetes Globally

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    Newswise — A research model of dietary intake in 184 countries, developed by researchers at the Friedman School of Nutrition Science and Policy at Tufts University, estimates that poor diet contributed to over 14.1 million cases of type 2 diabetes in 2018, representing over 70% of new diagnoses globally. The analysis, which looked at data from 1990 and 2018, provides valuable insight into which dietary factors are driving type 2 diabetes burden by world region. The study was published April 17 in the journal Nature Medicine.

    Of the 11 dietary factors considered, three had an outsized contribution to the rising global incidence of type 2 diabetes: Insufficient intake of whole grains, excesses of refined rice and wheat, and the overconsumption of processed meat. Factors such as drinking too much fruit juice and not eating enough non-starchy vegetables, nuts, or seeds, had less of an impact on new cases of the disease.

    “Our study suggests poor carbohydrate quality is a leading driver of diet-attributable type 2 diabetes globally, and with important variation by nation and over time,” says senior author Dariush Mozaffarian, Jean Mayer Professor of Nutrition and dean for policy at the Friedman School. “These new findings reveal critical areas for national and global focus to improve nutrition and reduce devastating burdens of diabetes.”

    Type 2 diabetes is characterized by the resistance of the body’s cells to insulin. Of the 184 countries included in the Nature Medicine study, all saw an increase in type 2 diabetes cases between 1990 and 2018, representing a growing burden on individuals, families, and healthcare systems.

    The research team based their model on information from the Global Dietary Database, along with population demographics from multiple sources, global type 2 diabetes incidence estimates, and data on how food choices impact people living with obesity and type 2 diabetes from multiple published papers.  

    The analysis revealed that poor diet is causing a larger proportion of total type 2 diabetes incidence in men versus women, in younger versus older adults, and in urban versus rural residents at the global level.

    Regionally, Central and Eastern Europe and Central Asia —particularly in Poland and Russia, where diets tend to be rich in red meat, processed meat, and potatoes —had the greatest number of type 2 diabetes cases linked to diet. Incidence was also high in Latin America and the Caribbean, especially in Colombia and Mexico, which was credited to high consumption of sugary drinks, processed meat, and low intake of whole grains.

    Regions where diet had less of an impact on type 2 diabetes cases included South Asia and Sub-Sharan Africa —though the largest increases in type 2 diabetes due to poor diet between 1990 and 2018 were observed in Sub-Saharan Africa. Of the 30 most populated countries studied, India, Nigeria, and Ethiopia had the fewest case of type 2 diabetes related to unhealthy eating.

    “Left unchecked and with incidence only projected to rise, type 2 diabetes will continue to impact population health, economic productivity, health care system capacity, and drive heath inequities worldwide,” says first author Meghan O’Hearn. She conducted this research while a PhD candidate at the Friedman School and currently works as Impact Director for Food Systems for the Future, a non-profit institute and for-profit fund that enables innovative food and agriculture enterprises to measurably improve nutrition outcomes for underserved and low-income communities. “These findings can help inform nutritional priorities for clinicians, policymakers, and private sector actors as they encourage healthier dietary choices that address this global epidemic.”

    Other recent studies have estimated that 40% of type 2 diabetes cases globally are attributed to suboptimal diet, lower than the 70% reported in the Nature Medicine paper. The research team attributes this to the new information in their analysis, such as the first ever inclusion of refined grains, which was one of the top contributors to diabetes burdens; and updated data on dietary habits based on national individual-level dietary surveys, rather than agricultural estimates. The investigators also note that they presented the uncertainty of these new estimates, which can continue to be refined as new data emerges.

     

    Research reported in this article was supported by the Bill and Melinda Gates Foundation. Complete information on authors, funders, methodology, and conflicts of interest is available in the published paper. The content is solely the responsibility of the authors and does not necessarily represent the official views of the funders.

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  • New ways to protect food crops from climate change and other disruptions

    New ways to protect food crops from climate change and other disruptions

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    Newswise — “There’s no doubt we can produce enough food for the world’s population – humanity is strategic enough to achieve that. The question is whether – because of war and conflict and corruption and destabilization – we do,” said World Food Programme leader David Beasley in an interview with Time magazine earlier this year.    

    Indeed, projections show that we are not on track to achieve Sustainable Development Goal 2 of Zero Hunger by 2030. As climate and security crises continue to destabilise our food sources, researchers are taking a critical look not just at how we produce food – but at the entire systems behind our food supplies. In this case, the systems behind the seeds that produce our food crops.    

    “Whilst adapting crops to climate change and conserving their variation is essential for food security, these measures are meaningless if farmers do not have access to the seeds,” says crop scientist and food system expert Ola Westengen. Westengen leads the team of researchers from the Norwegian University of Life Sciences (NMBU) who recently reviewed the state of seed systems for small-holder farmers in low/middle income countries. Their findings are now published in the Proceedings of the National Academy of Sciences (PNAS).   

    What are seed systems?    

    Seed systems are the provision, management and distribution of seeds. They cover the entire seed chain, from the conservation of their diversity and variety development, to their production and distribution, and the rules that govern these activities.  In short, they are the structures that make seeds available to farmers so that crops can be sown, harvested and end up on our plates.    

    Whilst a well-functioning seed system will ensure seed security for all farmers, the researchers say that, in practice, it is rarely the case that seed systems function as well as they might. Seed systems can be disrupted by conflict and disasters, as well as by problems stemming from social inequality, lack of coordination or inappropriate policies.      

    What does this study tell us that we don’t already know?   

    “There are recent innovations and investments by governments and donors to improve farmers’ access to diverse crop varieties and quality seeds,” explains Teshome Hunduma, a seed governance researcher and co-author of the study. “For example, there are now more flexible policies and regulations that encourage diversity in the seed systems used by farmers, rather than pushing farmers to switch to commercial seed systems that focus on less diverse commodity crops – which is the norm.” Commodity crops are those grown in large volume and high intensity for the purpose of sale, as opposed to those grown by small-holder farmers for direct processing and consumption.   

    “The study highlights emerging initiatives that are helping farmers to secure food supplies, such as participatory plant breeding,” says Teshome. Participatory plant breeding is the development and selection of new crop varieties where the farmers are in control. Farmers, who know the needs of their farms best, work with researchers and others to improve crops and develop plant varieties that are in line with their household needs and culture, and that are resilient to environmental and climate challenges.    

    “Farmers prefer and need different types of seeds, based on diverse social, cultural and ecological conditions,” adds ethnobotanist and co-author Sarah Paule Dalle.       

    The study discusses various disruptions to farmer’s access to seeds. Social inequality is one such disruption. How so?   

    “A seed system that only serves a segment of a farming society contributes to seed insecurity,” replies Teshome. “For example, commercial seed systems deliver high-yielding varieties of quality hybrid seeds. Whilst wealthy farmers can afford such seeds, poor farmers can’t.”    

    “Similarly, whilst commercial seed systems that focus on commodity crops may benefit men who might primarily be interested in market value, such systems have little to offer women who want crops that provide household nutrition and meet their cultural preferences.”   

    “This means poor farmers and women do not have the same access to seeds that meet their needs. The result is seed, and thus food, insecurity due to social and economic inequality.”     

    Political-economic factors have driven the globalization of food systems over the last decades, which also includes seed systems. “Seeds have become big business”, say the researchers. According to studies quoted in the article, the four largest multinational companies in seed trade today control about 60% of the ~50 billion USD global commercial seed market. The large private actors have the power not only to shape markets, but also to influence science and innovation agendas and policy frameworks.     

    This can be problematic, say the researchers, when private sector research and development typically focuses on the most profitable crops, such as maize and soy. Crops grown and consumed by subsistence farmers are thus largely neglected, and the potential of crop diversity – the foundation of agriculture – remains largely untapped. Technology that could help develop more robust varieties remains hypothetical.   

    How does the ownership of crop diversity threaten food supplies and what can be done?      

    The term crop diversity refers both to different crops and different varieties of a crop. According to the Global Crop Diversity Trust (one of the world’s primary international organizations on crop diversity conservation), securing and making available the world’s crop diversity is essential for future food and nutrition security.      

    “Plant breeders and scientists use crop diversity to develop new, more resilient and productive varieties that consumers want to eat, that are nutritious and tasty, and that are adapted to local preferences, environments and challenges,” explains Benjamin Kilian, a plant genetics expert at the Global Crop Diversity Trust. The Crop Trust, together with the Norwegian University of Life Sciences, implements the major project from which this study emerged: Biodiversity for Opportunities, Livelihoods and Development (BOLD). Coordinated by Kilian, the project supports the conservation and use of crop diversity to strengthen food and nutrition security on a global scale. It builds on the Crop Wild Relatives project and is funded by the Norwegian government.   

    “In the BOLD project, researchers work with genebanks, plant breeders and others in the seed value chain to co-develop seed systems that are both resilient to climate stresses and inclusive of small-holder farmers on the frontline of adaptation,” adds Westengen.     

    Will access to seeds in the vulnerable areas that you are studying be improved in time to make a difference?   

    “We hope so, if we make the right moves to include small-holder farmers in seed system development,” says Dalle. “A well-functioning seed system should also be resilient. That is, it should withstand shocks such as drought or pandemics and breakdowns or disruptions such as war and conflict.”    

    “To do this, the system should promote a diversity of seeds, both local varieties and those improved to better adapt to stresses. It should also involve diverse groups of people such as farmer cooperatives/groups, and both public and private companies to increase the choice of seeds and seed sources. During lockdowns in the COVID-19 pandemic, for example, farmers’ own seed systems enabled access to seeds in developing countries when the activities of private companies and agro-dealers were restricted,” explains Dalle.   

    Westengen summarizes: “Our study highlights links between the crucial work of the Global Crop Diversity Trust and the farmers on the frontline of adapting our food systems to climate change. It is an argument for co-designing seed system development in full cooperation with farmers and other actors in the seed system. This way, efforts can meet the needs of various groups of farmers in different agroecological contexts. There is no one-size-fits-all; if there is one natural law in biology, it is that diversity is key to future evolution. That also goes for seed systems – and food system development.”   

    Navigating towards resilient and inclusive seed systems by Ola T. Westengen, Sarah Paule Dalle and Teshome Hunduma Mulesa was published in Proceedings of the National Academy of Sciences (PNAS) this week. PNAS is widely considered one of the most prestigious and highly cited multidisciplinary research journals.   


    About the Norwegian University of Life Sciences (NMBU)  
    NMBU’s research and education enables people all over the world to tackle the big, global challenges regarding the environment, sustainable development, how to improve human and animal health, renewable energy sources, food production, and land- and resource management. 

     About the Crop Trust 
    The Crop Trust is an international organization working to conserve crop diversity and thus protect global food and nutrition security. At the core of Crop Trust is an endowment fund dedicated to providing guaranteed long-term financial support to key genebanks worldwide. The Crop Trust supports the Svalbard Global Seed Vault and coordinates large-scale projects worldwide to secure crop diversity and make it available for use. The Crop Trust is recognized as an essential element of the funding strategy of the International Treaty on Plant Genetic Resources for Food and Agriculture.  

    About the BOLD Project 
    BOLD (Biodiversity for Opportunities, Livelihoods, and Development) is a major 10-year project to strengthen food and nutrition security worldwide by supporting the conservation and use of crop diversity. The project works with national genebanks, pre-breeding and seed system partners globally. Funded by the government of Norway, BOLD is led by the Crop Trust in partnership with the Norwegian University of Life Sciences and the International Plant Treaty. 

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  • Crucial Antarctic ocean circulation heading for collapse if planet-warming pollution remains high, scientists warn | CNN

    Crucial Antarctic ocean circulation heading for collapse if planet-warming pollution remains high, scientists warn | CNN

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    Brisbane, Australia
    CNN
     — 

    Melting ice in the Antarctic is not just raising sea levels but slowing down the circulation of deep ocean water with vast implications for the global climate and for marine life, a new study warns.

    Led by scientists from the University of New South Wales and published Wednesday in the journal Nature, the peer-reviewed study modeled the impact of melting Antarctic ice on deep ocean currents that work to flush nutrients from the sea floor to fish near the surface.

    Three years of computer modeling found the Antarctic overturning circulation – also known as abyssal ocean overturning – is on track to slow 42% by 2050 if the world continues to burn fossil fuels and produce high levels of planet-heating pollution.

    A slow down is expected to speed up ice melt and potentially end an ocean system that has helped sustain life for thousands of years.

    “The projections we have make it look like the Antarctic overturning would collapse this century,” said Matthew England, deputy director of the Australian Research Council’s Centre for Excellence in Antarctic Science, who coordinated the study.

    “In the past, these overturning circulations changed over the course of 1,000 years or so, and we’re talking about changes within a few decades. So it is pretty dramatic,” he said.

    Most previous studies have focused on the Atlantic Meridional Overturning Circulation (AMOC), the system of currents that carry warm water from the tropics into the North Atlantic. The cold, saltier water then sinks and flows south.

    Its Southern Ocean equivalent is less studied but does an important job moving nutrient-dense water north from Antarctica, past New Zealand and into the North Pacific Ocean, the North Atlantic and Indian Ocean, the report’s authors said in a briefing.

    The circulation of deep ocean water is considered vital for the health of the sea – and plays an important role in sequestering carbon absorbed from the atmosphere.

    According to the report, while a slowdown of the AMOC would mean the deep Atlantic Ocean would get colder, the slower circulation of dense water in the Antarctic means the deepest waters of the Southern Ocean will warm up.

    “One of the concerning things of this slowdown is that there can be feedback to further ocean warming at the base of the ice shelves around Antarctica. And that would lead to more ice melt, reinforcing or amplifying the original change,” England said.

    As global temperatures rise, Antarctic ice is expected to melt faster, but that doesn’t mean the circulation of deep water will increase – in fact the opposite, scientists said.

    In a healthy system, the cold and salty – or dense – consistency of melted Antarctic ice allows it to sink to the deepest layer of the ocean. From there it sweeps north, carrying carbon and higher levels of oxygen than might otherwise be present in water around 4,000 meters deep.

    As the current moves northward, it agitates deep layers of debris on the ocean floor – remains of decomposing sea life thick with nutrients – that feed the bottom of the food chain, scientists said.

    In certain areas, mostly south of Australia in the Southern Ocean and in the tropics, this nutrient-rich cold water moves toward the surface in a process called upwelling, distributing the nutrients to higher layers of the ocean, England said.

    However, Wednesday’s study found that as global temperatures warm, melting sea ice “freshens” the water around Antarctica, diluting its saltiness and raising its temperature, meaning it’s less dense and doesn’t sink to the bottom as efficiently as it once did.

    The report’s co-author, Steve Rintoul from Australia’s Commonwealth Scientific and Industrial Research Organisation and the Australian Antarctic Program Partnership, said sea life in waters worldwide rely on nutrients brought back up to the surface, and that the Antarctic overturning is a key component of that upwelling of nutrients.

    “We know that nutrients exported from the Southern Ocean in other current systems support about three quarters of global phytoplankton production – the base of the food chain,” he said.

    “We’ve shown that the sinking of dense water near Antarctica will decline by 40% by 2050. And it’ll be sometime between 2050 and 2100 that we start to see the impacts of that on surface productivity.”

    England added: “People born today are going to be around then. So, it’s certainly stuff that will challenge societies in the future.”

    Fishing boats at a floating fish farm off Rongcheng, China.

    The report’s authors say the slowing of the Antarctic ocean overturning has other knock-on effects for the planet – for example, it could shift rain bands in the tropics by as much as 1,000 kilometers (621 miles).

    “Shut it down completely and you get this reduction of rainfall in one band south of the equator and an increase in the band to the north. So we could see impacts on rainfall in the tropics,” said England.

    Earlier this month, the Intergovernmental Panel on Climate Change (IPCC) warned in its latest report that the impacts of rising global temperatures were more severe than expected. Without immediate and deep changes, the world is hurtling toward increasingly dangerous and irreversible consequences of climate change, it added.

    The IPCC report found that the goal of limiting global warming to 1.5 degrees Celsius (2.7 degrees Fahrenheit) above preindustrial levels was still possible, but it’s becoming harder to achieve the longer the world fails to cut carbon pollution.

    England points out that the IPCC predictions don’t include ice melt from Antarctic ice sheets and shelves.

    “That’s a very significant component of change that’s already underway around Antarctica with more to come in the next few decades,” England said.

    Rintoul said the study was another urgent warning on top of all the ones that have come before it.

    “Even though the direct effect on fisheries through reduced nutrient supply might take decades to play out, we will commit ourselves to that future with the choices we make over the next decade.”

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  • Technology to protect bioactive compounds from food during digestion

    Technology to protect bioactive compounds from food during digestion

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    Newswise — Bioactive compounds present mostly in fruit and vegetables perform different bodily functions relating to health and well-being. Their effects are considered antioxidant, antidiabetic, antiaging and anticancer, among others.

    Many studies are looking for ways to optimize absorption of bioactive compounds by the organism and increase their bioavailability – the proportion that enters the bloodstream after absorption. One way is to coat the compounds with another material and package them on the nanometric scale (a nanometer is a billionth of a meter). Nanoencapsulation, as this technique is known, assures slow release of the compounds so that they take longer to digest and can survive the attacks of bacteria in the gut microbiome.

    An investigation conducted by a duo of researchers at the University of São Paulo’s School of Pharmaceutical Sciences (FCF-USP) in Brazil is one of these studies. Working at the school’s Department of Food Science and Experimental Nutrition, they have produced several articles on the subject – the latest of which, published in the International Journal of Biological Macromolecules, is a review of the literature on pectin-based nanoencapsulation plus a description of a novel technology developed under the aegis of the Food Research Center (FoRC), a Research, Innovation and Dissemination Center (RIDCsupported by FAPESP.

    “We used pectin extracted from residues of citrus fruit albedo and peel, with a degree of purity permitting human ingestion and excluding any kind of hazardous chemical,” said João Paulo Fabi, one of the authors and a professor at FCF-USP. Albedo is the layer of white spongy material inside the peel of oranges and lemons, for example.

    “In addition to our review of the literature, we describe a novel technology for nanoencapsulation of bioactive compounds using pectin. This entails producing a pectin-lysozyme complex as a protective outer layer for a highly sensitive bioactive compound called anthocyanin,” he explained, adding that lysozyme is “a safely edible substance obtained from egg white and used to enhance the stability of the end-product”.

    Anthocyanins are water-soluble pigments belonging to the flavonoid family. They are phenolic compounds found in all plants and responsible for the shades of red, blue and purple seen in flowers, fruit, leaves, stalks and roots.

    The authors say their methodology can be used to encapsulate other water-soluble bioactive compounds. “We tested anthocyanin because of its challenging sensitivity to many factors, such as light, temperature, pH and gut bacteria,” said Thiécla Katiane Osvaldt Rosales, the other author. She is currently a postdoctoral researcher at the Nuclear and Energy Research Institute (IPEN).

    Besides FoRC, FAPESP also funded the research via support for two other projects (19/11816-8 and 12/23970-2). 

    Advantages of methodology

    According to the researchers, the main advantage of their methodology is that no other compounds are added apart from pectin, lysozyme and anthocyanin. “We used three compounds from sources in nature and mixed them in the laboratory to form a new product, without adding salts, ligands or anything potentially toxic. Furthermore, the nanoparticles are not too small. Very tiny nanoparticles can penetrate barriers and cell membranes, entering the DNA and having toxic effects. The size we obtained is safe,” Fabi said.

    Rosales outlined the process they developed to produce the nanoparticles. “Pectin and lysozyme are heated separately. The increase in temperature partly alters their structure, and they interact better when heated. They are then rapidly cooled to reach a temperature not harmful to anthocyanin, which is sensitive and fairly unstable. The three substances are blended in an aqueous suspension and agitated for an hour. The result is encapsulated anthocyanin. The suspension is then filtered to separate the non-encapsulated contents,” she said.

    Special care is taken with factors such as temperature and pH. “We tested the parameters for the purpose of optimization, especially pH. If pH is too high, the anthocyanin breaks down. It can’t be too low, either. We found a pH of 5 to be optimal for interaction between the molecules,” she explained. “We also tested the duration and intensity of the agitation. We made a point of managing all the details, however minor, because they make a difference in terms of forming stable particles. We’ve applied for a patent on the methodology.”

    Results

    Finally, the encapsulation was tested for efficacy in a digestion system simulated in the laboratory to mimic the gastric and intestinal phases. “The result was that part of the anthocyanin was released during the digestive process, at the end of gastric digestion, and part remained in the nanostructure, with the possibility of release of this remainder in the gut or absorption together with the nanostructure. We believe this was a good outcome. Partial and gradual release suggests absorption of the compound starts before it enters the gut, with the nanoencapsulated remainder probably being released in the gut or fully absorbed with less structural alteration,” Rosales said.

    The next step will be animal testing. “We tested the method in vitro and obtained results indicating that the nanoparticles are safe for consumption. We have evidence that cells can absorb them in a non-toxic manner and that the pectin protects the anthocyanin and its properties. We now have to test it in animals, observing the process of oral ingestion, absorption of the anthocyanin using specific markers for absorption, and the route followed in the organism. It’s important to verify the extent of absorption and the biological destination,” she said.

    The nanoparticles are mainly intended for use as a food supplement. “They can be added to food and dietary supplements, but industrial mass production would be necessary to include them in a supplement,” Fabi said.

    It is worth noting that the method does not require expensive equipment or procedures. “In addition, the material used for the nanocapsules, which comes from byproducts of citrus peel, would make the cost even lower for manufacturers. The pectin we used in our study is available commercially and is used by the food industry, mostly for gel formation in jam or as a thickener,” Rosales said.

    About São Paulo Research Foundation (FAPESP)

    The São Paulo Research Foundation (FAPESP) is a public institution with the mission of supporting scientific research in all fields of knowledge by awarding scholarships, fellowships and grants to investigators linked with higher education and research institutions in the State of São Paulo, Brazil. FAPESP is aware that the very best research can only be done by working with the best researchers internationally. Therefore, it has established partnerships with funding agencies, higher education, private companies, and research organizations in other countries known for the quality of their research and has been encouraging scientists funded by its grants to further develop their international collaboration. You can learn more about FAPESP at www.fapesp.br/en and visit FAPESP news agency at www.agencia.fapesp.br/en to keep updated with the latest scientific breakthroughs FAPESP helps achieve through its many programs, awards and research centers. You may also subscribe to FAPESP news agency at http://agencia.fapesp.br/subscribe.

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  • FDA sketches out plan to bolster fragile US infant formula supply management | CNN

    FDA sketches out plan to bolster fragile US infant formula supply management | CNN

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    CNN
     — 

    The US Food and Drug Administration announced Tuesday its initial strategy to boost and strengthen the management of the country’s supply of infant formula.

    The announcement came just ahead of a hearing of the House Oversight and Accountability Committee about what went wrong during last year’s infant formula shortage.

    Committee members and experts who testified were critical of formula makers and the FDA’s food safety program, which the agency has pledged to revamp in order to protect the nation’s food supply and promote better nutrition. Many experts are concerned that the formula shortage of 2022 could easily happen again, even with those changes.

    “While we stand here today, more than a year since the recall, it is my view that the state of the infant formula industry today is not much different than it was then,” testified Frank Yiannas, who stepped down from his role as the agency’s deputy commissioner of food policy and response in late February.

    “The nation remains one outbreak, one tornado, flood or cyberattack away from finding itself in a similar place to that of February 17, 2022.”

    A formula shortage that started in 2021 was exacerbated when the United States’ largest infant formula maker, Abbott Nutrition, recalled multiple products in mid-February and had to pause production after FDA inspectors found potentially dangerous bacteria at its Sturgis, Michigan, plant.

    A former Abbott employee filed a whistleblower complaint about the plant with the US Department of Labor’s Occupational Safety and Health Administration in February 2021. The complaint suggested that the plant lacked proper cleaning practices and that workers falsified records and hid information from inspectors.

    The complaint was filed February 16, 2021, and was passed on to Abbott and the FDA three days later.

    Yiannas testified that because of the siloed nature of the agency, he wasn’t made aware of the complaint until February 2022. It was only then that he learned that children had gotten sick with Cronobacter after consuming powdered formula made at the plant.

    The US Centers for Disease Control and Prevention investigated at least four illnesses and two deaths in three states in connection. The agency sequenced bacteria from two of the children to compare against the samples the FDA took at the facility, but it did not find that the samples were closely related.

    Cronobacter infections are rare but can be serious and even fatal, especially in newborns. The bacteria lives in the environment, but when these infections are diagnosed in infants, they are often linked to powdered formula.

    “Clearly, I really wish, and I should have been notified sooner, so I could have initiated containment steps earlier. Had that happened, I believe we might not be here today,” Yiannas said Tuesday. “Had the agency responded quicker to some of the earlier signals, I believe this crisis could have been averted or at least the magnitude lessened.”

    With more demand for other brands after the Abbott recalls, families across the country had to hunt through multiple stores for formula last year. Stock rates of baby formula stayed lower than they were the year before for much of 2022. Even in October, when rates had improved, nearly a third of households with a baby younger than 1 said they had trouble finding formula over the course of one week, according to a survey by the US Census Bureau.

    The FDA said Tuesday that its new national strategy helps ensure that the country’s supply of formula will remain constant and safe.

    The agency said it will work with the industry on redundancy risk management plans that will help companies identify possible supply chain problems. It will also continue to enhance inspections of infant formula plants by expanding and improving training for agency investigators.

    According to the strategy, the FDA will expedite review of premarket submissions for new products to prevent shortages. It will continue to closely monitor the formula supply and has developed a model to forecast any potential disruptions.

    It also plans to work closely with the US Department of Agriculture to build in more resiliency with its Special Supplemental Nutrition Program for Women, Infants, and Children program, or WIC, the nation’s largest purchaser of infant formula.

    The new strategy is just a first step; the long-term strategy is expected to be released in early 2024.

    Dr. Susan Mayne, director of the FDA’s Center for Food Safety and Applied Nutrition, said in a statement that the new strategy aims to incentivize “additional infant formula manufacturers to enter the market.”

    Many parts of the strategy are underway, the FDA said.

    “Safety and supply go hand-in-hand. We witnessed last year how a safety concern at one facility could be the catalyst for a nationwide shortage. That’s why we are looking to both strengthen and diversify the market, while also ensuring that manufacturers are producing infant formula under the safest conditions possible,” FDA Commissioner Dr. Robert Califf said in a news release. “Now, with this strategy, we are looking at how to advance long-term stability in this market and mitigate future shortages, while ensuring formula is safe.”

    Formula stock rates are still not where they once were before last year’s crisis, Yiannas said, but the problem can’t be solved overnight. He said it was a good step for Congress to ask for a resiliency report from the industry.

    One positive development that came out of the crisis is that manufacturers are reporting formula volume to the FDA on a weekly basis even though there is no legal requirement to do so, he said.

    Historically, the FDA has focused on food safety and nutrition, not supply chain availability, but the Covid-19 pandemic opened eyes and served as the “biggest test on the US food system in 100 years,” Yiannas said. Food supply shortages made experts realize that the agency needed more intelligence on how companies’ supply chains worked.

    “Progress is being made, but it’s not being made fast enough,” Yiannas said.

    The FDA is now tracking sales and stock rates of baby formula. He said he’s talked to formula companies that say they have ramped up production, even though they might have cut back on the number of varieties of product they offer.

    The FDA said Tuesday that it has also done a study to better understand what led to the recall of infant formula at the Abbott plant. The agency had conducted a routine surveillance inspection at the plant in September 2021 and even then found problems like standing water and inadequate handwashing among employees.

    Abbott is facing additional investigations from the US Securities and Exchange Commission, the US Federal Trade Commission and the US Department of Justice as well as lawsuits from customers.

    Yiannas told the House committee Tuesday that one strategy to head off similar shutdowns would be to require manufacturers to report Cronobacter bacteria found in its products. Currently, only the Abbott plant in Michigan is required to report the bacteria as part of the consent decree that allowed it to reopen.

    The FDA said in November that it would like Cronobacter infections added to the CDC’s list of national notifiable diseases, which would require doctors to report cases to public health officials so the CDC and the FDA could keep better track of infections. Only two states have such a reporting requirement now.

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  • The heart benefits of walnuts likely come from the gut

    The heart benefits of walnuts likely come from the gut

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    Newswise — A new study examining the gene expression of gut microbes suggests that the heart-healthy benefits of walnuts may be linked to beneficial changes in the mix of microbes found in our gut. The findings could help identify other foods or supplements with similar nutritional benefits.

    Researchers led by Kristina S. Petersen from Texas Tech University in Lubbock found that introducing walnuts into a person’s diet may alter the gut’s mix of microbes — known as the microbiome — in a way that increases the body’s production of the amino acid L-homoarginine. Homoarginine deficiency has been linked to higher risk for cardiovascular disease.

    “Research has shown that walnuts may have heart-healthy benefits like lowering cholesterol levels and blood pressure,” said Mansi Chandra, an undergraduate researcher at Juniata College in Huntingdon, Pennsylvania. “This motivated us to look at how walnuts benefited the gut microbiome and whether those effects led to the potential beneficial effects. Our findings represent a new mechanism through which walnuts may lower cardiovascular disease risk.”

    Chandra will present the new findings at Discover BMB, the annual meeting of the American Society for Biochemistry and Molecular Biology, March 25–28 in Seattle.

    The researchers used an approach known as metatranscriptomics to study the gene expression of gut microbes. This recently developed technology can be used to quantify gene expression levels and monitor how these levels shift in response to various conditions such as dietary changes.

    “To our knowledge, this is the first study to use metatranscriptomics analysis for studying the impact of walnut consumption on the gut microbiota gene expression,” Chandra said. “These exploratory analyses contribute to our understanding of walnut-related modulation of gut microbiome, which could be very impactful in learning how gut health impacts our heart health in general.”

    The metatranscriptomics analysis used samples acquired from a previously performed controlled-feeding study in which 35 participants with high cardiovascular risk were put on a two-week standard Western diet and then randomly assigned to one of three study diets. The study participants followed each diet for six weeks with a break between each.

    The diets included one that incorporated whole walnuts, one that included the same amount of omega-3 fatty acid alpha-linolenic acid, or ALA, and polyunsaturated fatty acids as the walnut diet but without walnuts, and one that partially substituted another fatty acid known as oleic acid for the same amount of ALA found in walnuts but without consumption of any walnuts. The diets were designed to provide information about how walnuts affected cardiovascular health due to their bioactive compounds and ALA content and whether walnut ALA is the best substitute for dietary saturated fat compared to oleic acid.

    For the new work, researchers used metatranscriptomics to analyze gene expression and the bacteria in the gastrointestinal tract from fecal samples collected shortly before the participants finished the run-in diet and each of the three study diets.

    The analysis revealed higher levels of Gordonibacter bacteria in the gut of participants on the walnut diet. This bacterium converts the plant polyphenols ellagitannins and ellagic acid into metabolites that allow them to be absorbed by the body. Participants consuming the walnut diet also showed higher levels of expression for several genes that are involved in important metabolic and biosynthetic pathways, including ones that increase the body’s production of the amino acid L-homoarginine.

    Although more work is needed to confirm these observations, the research could eventually help inform dietary interventions based on walnuts. “Since a lot of people are allergic to nuts, these findings also suggest that other food supplements that boost the endogenous production of homoarginine may also be helpful,” Chandra said.

    Next, the researchers would like to apply metabolomic and proteomic analyses to identify the final products of the genes that showed higher levels of expression. This would allow them to better understand the biological mechanisms at work.

     

    Mansi Chandra will present this research during the Undergraduate Poster Competition from noon to 3:30 p.m. PDT on Saturday, March 25, and during the poster session from 4:30 to 6:30 p.m. PDT on Sunday, March 26, in Exhibit Hall 4AB of the Seattle Convention Center (Poster Board No. 25) (abstract). Contact the media team for more information or to obtain a free press pass to attend the meeting.

     

    Image available.

     

    This release may include updated data or information that differs from the abstract submitted to the Discover BMB meeting.

     

    Kristina S. Petersen was previously affiliated with Pennsylvania State University.

     

    This study was funded by the California Walnut Commission. The research was also supported by the Penn State Clinical and Translational Research Institute, Pennsylvania State University Clinical and Translational Science Award and NIH/National Center for Advancing Translational Sciences (Grant UL1TR000127).

     

    About the American Society for Biochemistry and Molecular Biology (ASBMB)

    The ASBMB is a nonprofit scientific and educational organization with more than 12,000 members worldwide. Founded in 1906 to advance the science of biochemistry and molecular biology, the society publishes three peer-reviewed journals, advocates for funding of basic research and education, supports science education at all levels, and promotes the diversity of individuals entering the scientific workforce. www.asbmb.org

    Find more news briefs and tipsheets at https://discoverbmb.asbmb.org/newsroom.

     

     

     

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  • After Breast Cancer: Fitness and Nutrition Tips

    After Breast Cancer: Fitness and Nutrition Tips

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    When you finish treatment for breast cancer, you might have a mix of feelings. Going through treatment is physically and mentally exhausting, with many side effects from chemotherapy, radiation, surgery, and immunotherapy. Once the treatment phase is over, is there anything you can do to boost your odds of staying cancer-free?

    The answer is YES. There’s a lot you can do in your everyday life — in addition to taking any meds your doctor prescribes to help prevent recurrence and keeping up with your screenings.

    Cancer experts have long advised breast cancer survivors that the same healthy lifestyle habits that have been shown to lower your chance of developing breast cancer in the first place are also likely to cut the risk of breast cancer recurrence. In the past, that advice was based mostly on expert opinion.

    But more recently, studies specifically done on breast cancer survivors have added weight to that opinion. These findings suggest that regular physical activity and a healthy diet that is high in vegetables, fruits, whole grains, and beans and low in processed carbohydrates and high in fiber can help guard against breast recurrence and death.

    You’ve Got to Move It, Move It

    Being physically active has clear benefits.

    Women who got regular physical activity before their cancer diagnosis and after treatment are less likely to have their cancer come back or to die compared with those who were inactive. That’s according to a 2020 study from researchers at Roswell Park Comprehensive Cancer Center in Buffalo, NY. 

    The study focused on 1,340 women with breast cancer and the Department of Health and Human Services (HHS) physical activity guidelines for adults, which are to get at least 150 minutes of moderate-intensity physical activity and 2 days of muscle-strengthening activity every week. In the study, women who did that were less likely to have their cancer come back than those who were inactive. They also were less likely to die over the 2 years of the study period. Even those who were considered to be “low active,” meaning that they came close to meeting the recommended activity levels but didn’t quite get there, had improved survival, as well. 

    Fitness Tips for Breast Cancer Survivors

    Your body has been through a lot – from the cancer itself to the treatments for it. No one is expecting you to run a marathon unless you want to. But don’t underestimate the power of regular movement.

     

    Start small. Even a daily 15-minute walk has benefits. “You don’t have to do a lot of intense workouts to benefit,” says Karen Basen-Engquist, PhD, the director of the Center for Energy Balance in Cancer Prevention and Survivorship at The University of Texas MD Anderson Cancer Center. “It can be hard to begin exercising when you’re experiencing fatigue related to cancer treatment, but moving just a small amount most days can help you reach the point where you can do more.”

    Tell your doctor. You may have glossed over the guidance you often see in fitness magazines: “Consult your doctor before starting any exercise program.” Don’t ignore that advice this time. Check with your treatment team to see how much exercise they feel you can handle at this point in your recovery.

    Set realistic expectations. If you were running an 8-minute mile before you started chemotherapy, don’t expect to be able to match that pace 3 or 4 months after your last dose. And that’s OK.

    Don’t stress your bones and joints. This is especially important if you’ve had bone loss related to chemotherapy. Instead of running or high-impact aerobics, which could add to your risk of fractures, start with walking. Or try swimming, a no-impact way to work your muscles and your cardiovascular system.

    Be aware of your ability to balance. If you have neuropathy (tingling or numbness) in your feet or hands after chemotherapy, that can affect your balance. Be careful about activities where you might risk falling. Instead of running on a treadmill, for example, you might prefer to work out on an exercise bicycle.

    Make time for strength training. It can make a difference in your daily life. “While we can’t say whether or not it improves overall survival, the evidence shows that breast cancer survivors who do strength training see improvements in their fatigue, quality of life, and physical functioning,” Basen-Engquist says.

    What to Eat: Leafy Greens and Smart Carb Intake

    What about food? The good news is that the general principles of healthy eating are also beneficial for breast cancer survivors.

    Two recent studies suggest that a healthy diet can help breast cancer survivors live longer. Both studies involve data from about a quarter of a million women who took part in two large observational studies called the Nurses’ Health Studies. The studies followed these women, all of whom were under 55 and cancer-free when they began, for up to 30 years. By 2011, about 9,000 of the study participants had been diagnosed with breast cancer.

    The first study found that women who ate the greatest amounts of fruits and vegetables after their breast cancer diagnosis had an overall lower risk of dying during the course of the study compared to those who ate the least amounts. 

    When the researchers dug deeper, they found that it was leafy greens and cruciferous vegetables like broccoli, cauliflower, and Brussels sprouts that were driving most of the benefits. Women who ate almost a full serving of cruciferous vegetables daily had a 13% lower risk of dying from any cause during the study, compared to those who ate almost none of these vegetables. And women who ate almost two servings of leafy greens daily were 20% less likely to die, compared to those who ate almost no greens.

    Carbs were key in the second study – specifically, what kinds or types of carbs women ate. It found that high glycemic load carbs — those that cause your blood sugar to spike, like sugary beverages, processed foods like chips and doughnuts, and fast food like cheeseburgers and french fries — posed an increased risk. Breast cancer survivors with high glycemic load diets were more likely to die of breast cancer than those who ate lower glycemic load diets. They also found that women who ate high-fiber diets had a lower risk of death than those who ate diets low in fiber.

    The bottom line: Eat more fruits, vegetables, and whole grains. 

    “Taken together, the research suggests that women diagnosed with breast cancer may benefit from eating a diet high in fruits and vegetables and eating less rapidly digested foods sources, such as whole grains and non-starchy vegetables,” says Nigel Brockton, PhD, vice president of research for the American Institute of Cancer Research (AICR). 

    And there was good news for fans of tofu and edamame: Despite past concerns that the estrogen-like properties of soy might contribute to breast cancer, evidence now shows that the opposite is true. “If anything, soy has a beneficial effect and may even reduce the risk of breast cancer recurrence,” Brockton says.

    Maintaining a Healthy Weight 

    In general, getting regular physical activity and eating a healthy diet can help keep you from gaining too much weight, something that researchers have also found is important after breast cancer. 

    “There is strong evidence that a higher body mass index after diagnosis is associated with poorer outcomes in breast cancer,” Brockton says. “Avoiding weight gain and doing your best to stay at a healthy weight is important.”

    Overall, Brockton says that the AICR’s recommendations about diet and physical activity for cancer prevention are still wise advice for breast cancer survivors to avoid a recurrence. These include:

    • Maintain a healthy weight.
    • Be physically active.
    • Eat more whole grains, vegetables, fruits, and legumes (like beans).
    • Avoid sugary drinks and limit your intake of fast foods and processed foods high in fats, starches, and sugars.
    • Limit red meats like beef, pork, and lamb.
    • Avoid processed meats and alcohol.

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