ReportWire

Tag: Ethics and Research Methods

  • Some mosquitoes like it hot

    Some mosquitoes like it hot

    Newswise — Certain populations of mosquitoes are more heat tolerant and better equipped to survive heat waves than others, according to new research from Washington University in St. Louis.

    This is bad news in a world where vector-borne diseases are an increasingly global health concern. Most models that scientists use to estimate vector-borne disease risk currently assume that mosquito heat tolerances do not vary. As a result, these models may underestimate mosquitoes’ ability to spread diseases in a warming world.

    Researchers led by Katie M. Westby, a senior scientist at Tyson Research Center, Washington University’s environmental field station, conducted a new study that measured the critical thermal maximum (CTmax), an organism’s upper thermal tolerance limit, of eight populations of the globally invasive tiger mosquito, Aedes albopictus. The tiger mosquito is a known vector for many viruses including West Nile, chikungunya and dengue.

    “We found significant differences across populations for both adults and larvae, and these differences were more pronounced for adults,” Westby said. The new study is published Jan. 8 in Frontiers in Ecology and Evolution.

    Westby’s team sampled mosquitoes from eight different populations spanning four climate zones across the eastern United States, including mosquitoes from locations in New Orleans; St. Augustine, Fla.; Huntsville, Ala.; Stillwater, Okla.; St. Louis; Urbana, Ill.; College Park, Md.; and Allegheny County, Pa.

    The scientists collected eggs in the wild and raised larvae from the different geographic locations to adult stages in the lab, tending the mosquito populations separately as they continued to breed and grow. The scientists then used adults and larvae from subsequent generations of these captive-raised mosquitoes in trials to determine CTmax values, ramping up air and water temperatures at a rate of 1 degree Celsius per minute using established research protocols.

    The team then tested the relationship between climatic variables measured near each population source and the CTmax of adults and larvae. The scientists found significant differences among the mosquito populations.

    The differences did not appear to follow a simple latitudinal or temperature-dependent pattern, but there were some important trends. Mosquito populations from locations with higher precipitation had higher CTmax values. Overall, the results reveal that mean and maximum seasonal temperatures, relative humidity and annual precipitation may all be important climatic factors in determining CTmax.

    “Larvae had significantly higher thermal limits than adults, and this likely results from different selection pressures for terrestrial adults and aquatic larvae,” said Benjamin Orlinick, first author of the paper and a former undergraduate research fellow at Tyson Research Center. “It appears that adult Ae. albopictus are experiencing temperatures closer to their CTmax than larvae, possibly explaining why there are more differences among adult populations.”

    “The overall trend is for increased heat tolerance with increasing precipitation,” Westby said. “It could be that wetter climates allow mosquitoes to endure hotter temperatures due to decreases in desiccation, as humidity and temperature are known to interact and influence mosquito survival.”

    Little is known about how different vector populations, like those of this kind of mosquito, are adapted to their local climate, nor the potential for vectors to adapt to a rapidly changing climate. This study is one of the few to consider the upper limits of survivability in high temperatures — akin to heat waves — as opposed to the limits imposed by cold winters.

    “Standing genetic variation in heat tolerance is necessary for organisms to adapt to higher temperatures,” Westby said. “That’s why it was important for us to experimentally determine if this mosquito exhibits variation before we can begin to test how, or if, it will adapt to a warmer world.”

    Future research in the lab aims to determine the upper limits that mosquitoes will seek out hosts for blood meals in the field, where they spend the hottest parts of the day when temperatures get above those thresholds, and if they are already adapting to higher temperatures. “Determining this is key to understanding how climate change will impact disease transmission in the real world,” Westby said. “Mosquitoes in the wild experience fluctuating daily temperatures and humidity that we cannot fully replicate in the lab.”

    Washington University in St. Louis

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  • Reshaping Financial Content: Enhancing Consumer Appreciation in Australian Professional Practice

    Reshaping Financial Content: Enhancing Consumer Appreciation in Australian Professional Practice

    Newswise — These limitations prompted Ben Neilson from the University of Southern Queensland to investigate the impact of these laborious documents on consumer appreciation, focusing on the key pillars of comprehension, value and trust.

    Neilson initially collected data to assess consumer appreciation levels of the current SOA financial content structure. This data was gathered through a combination of qualitative interviews and quantitative analysis.

    With this valuable data in hand, the researcher introduced a reimagined financial content structure that incorporated language improvements, explanatory videos, and hyperlinks. Subsequently, the impact of this new structure on consumer appreciation was evaluated and compared to the existing structure using a combination of thematic analysis, MANOVA and econometric modeling.

    “The findings revealed that the structure of financial content significantly influences consumer appreciation, particularly with respect to clarity, organization and formatting, all of which play pivotal roles in shaping decision-making processes,” shared Neilson. “Notably, our restructured financial content received higher levels of consumer appreciation, suggesting the potential for a shift in Australian professional practice.”

    The study, published in The Journal of Finance and Data Science, provides evidence that may contribute to debates surrounding consumer serviceability, relationship quality, and content structure of SOA documents in the Australian landscape. This may potentially encourage a redesign of SOA content structure.

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    References

    DOI

    10.1016/j.jfds.2023.100103

    Original Source URL

    https://doi.org/10.1016/j.jfds.2023.100103

    Journal

    The Journal of Finance and Data Science

    Chinese Academy of Sciences

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  • COVID-19 narratives through public health humanities

    COVID-19 narratives through public health humanities

    Newswise — COLUMBIA, Mo. — A new health humanities essay from the University of Missouri highlights how the narrative of many news stories detailing the challenges of health care workers during the COVID-19 pandemic often emphasized individual experiences. However, many of these news stories often left out broader public health, socioeconomic and environmental contexts that are critical to how consumers of news shape their thoughts about the pandemic and how to respond.

    By introducing a storytelling framework that emphasizes the core tenets of public health, the authors hope to help journalists, policymakers and public health humanities experts reframe not just how they view and tell stories about the COVID-19 pandemic, but also how scientific information gets disseminated, absorbed or rejected, and what emotions that data conjures up in consumers of news.

    Lise Saffran, an associate teaching professor in the MU College of Health Sciences and lead researcher on the essay, analyzed how health care workers were characterized during the COVID-19 pandemic in the narrative storytelling of American newspapers and television news stories. She then categorized the stories into three common themes related to clinicians as vulnerable front-line workers, clinician frustration with vaccine and masking resistance, and the clinician as a hero.

    Clinicians as vulnerable front-line workers

    While countless news stories highlighted the risk to individual health care workers assisting infected patients in the hospital, stories about the nearly 7 million essential low-wage workers, such as housekeepers and personal care aides, who are disproportionately women and people of color, were much rarer, even though they were being exposed to COVID-19 at a higher rate than the general public.  

    “It’s not that the stories being told are inaccurate, they are just often incomplete or fail to incorporate the broader contexts that give a more holistic view of the situation,” Saffran said. “For example, there were plenty of stories detailing bosses requesting their employees to return to in-person work instead of remote work, but a more wholistic story could be also mentioning at-risk populations, such as grocery store workers, who had no option to work remotely in the first place. Broadening the story not only can help increase feelings of empathy and compassion, but it could also spark discussions for how policymakers can potentially address the structural and systematic inequities at play.”

    Clinician frustration with vaccine and masking resistance

    Some news stories detailed clinicians who originally stated they had no sympathy toward people who chose not to get vaccinated and then suddenly gained compassion toward an unvaccinated patient once they realized the patient had been potentially misled or misinformed.

    “Instead of only telling the story about these specific individuals, how do we broaden the conversation to think about unvaccinated individuals who have not gotten sick yet. How do we think about vaccine hesitancy in general rather than only thinking about it when someone gets sick,” Saffran said. “Broadening the story helps us reframe the way we think about ideas of blame, responsibility, empathy and compassion. This is where a public health framework comes into play, by thinking about the upstream causes and broader contexts that impact overall populations, rather than just looking at the choices of an individual.”

    Clinicians as heroes

    News stories often highlighted the heroics of clinicians in hospitals without the proper personal protective equipment (PPE) or adequate staffing levels who put their own health at risk to help patients.

    “While these workers certainly are heroes, how do we frame the narrative around possible solutions to the structural and systematic failures, whether it be a lack of PPE or staffing shortages, that are forcing the clinicians to be heroes in the first place,” Saffran said. “We also tend to tell stories through the American lens, but in less developed, less industrialized countries, these gaps in health care, gaps in adequate PPE or gaps in staff are often larger. So how we frame these stories informs how we react. Do we ask clinicians to be heroes, or do we try to change the system to fill the gaps?”

    Implications going forward

    Saffran’s ultimate goal is to help storytellers broaden their narrative through a more holistic public health humanities framework, which has implications for both increasing feelings of empathy and compassion, as well as influencing policy decisions to address societal inequities and help improve the health outcomes of underserved populations.

    “Whether we realize it or not, when we consume news stories, this is how we develop our ideas of what policy should look like, we ask questions like ‘why is this happening?’ and ‘what should we do about it?’,” said Saffran, who teaches public health storytelling and earned a master’s degree in fine arts and creative writing from the University of Iowa Writer’s Workshop. “Humans don’t approach science and data strictly through an analytical lens, we engage with material through our values, identity and fears, which incorporate the humanities as well.”

    “‘You just emotionally break’: understanding COVID-19 narratives through public health humanities,” was recently published in Medical Humanities. Ashti Doobay-Persaud was a coauthor on the study.

    University of Missouri, Columbia

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  • Researchers prefer same-gender co-authors, study confirms

    Researchers prefer same-gender co-authors, study confirms

    Newswise — ITHACA, N.Y. – Researchers are more likely to pen scientific papers with co-authors of the same gender, a pattern that cannot be simply explained by the varying gender representation across scientific disciplines and time, according to joint research from Cornell University and the University of Washington.

    Mining a digital corpus of 560,000 published research articles over a 50-year period, the research team observed consistent gender homophily – the tendency of authors to collaborate with others who share their gender. While this observation by itself is not new, the researchers went further, using novel methods to rule out seemingly logical explanations – like a field’s gender balance, say, or a field’s authorship norms for writing research papers. 

    The team’s findings suggest a behavioral component is in play when scientists seek out collaborators.

    “One might posit that the gender homophily observed when considering a broad scientific landscape may be due to varying levels of gender representation,” said Y. Samuel Wang, assistant professor of statistics and data science and author of “Gender-Based Homophily in Collaborations Across a Heterogeneous Scholarly Landscape,” which was published in PLOS One. “However, our findings suggest that something beyond that is going on.”

    Comprising scholars in statistics, information science, biology and philosophy, the team mined a massive corpus of articles published between 1960 and 2011 from the online repository JSTOR. To help link genders to more than 800,000 author names, the team relied on social security records and crowdsourced data. Because of the limitations in the data set, this research was limited to men and women authors and didn’t factor in nonbinary identities, researchers said.

    From there, the team grouped authors from the same fields and eras, creating 50,000 hypothetical reconfigurations of authors.

    “We re-simulated hypothetical datasets. Our thinking was: How different is what we actually observed versus these hypothetical scenarios that we constructed?” said Wang, also an assistant professor of social statistics in the ILR School. “Very different, it turns out. This suggests that some other source of homophily is occurring in the data we observed.”

    As to why researchers tend to collaborate with those of the same gender, Wang and his team can’t say definitively. Data science methods can’t measure intent – why collaborators choose who they choose, but the team’s findings suggest that consideration of gender may be a factor, Wang said.

    Wang’s University of Washington co-authors are: Carole J. Lee, associate professor of philosophy; Jevin D. West, associate professor in the Information School; Carl T. Bergstrom, professor of biology, and Elena A. Erosheva, professor of statistics and social work.

    This research was supported by the National Science Foundation and the University of Washington’s Royalty Research Fund.

    For additional information, see this Cornell Chronicle story.

    -30-

    Cornell University

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  • Department of Energy User Facility Launches Platform for Analyzing Biological and Environmental Research Data

    Department of Energy User Facility Launches Platform for Analyzing Biological and Environmental Research Data

    Newswise — The Environmental Molecular Sciences Laboratory (EMSL) has launched the Data Transformations Integrated Research Platform (IRP) to help researchers from the world to  turn their research data into usable streams. 

    Through the new IRP, a range of innovative and standardized workflows are under development to help scientistis transform their scientific data into more manageable sets of information, make the data more accessible and analyses more reproducible, and facilitate the creation of models and visualization tools that help tell a larger story from the data. In addition to rigorous statistical methods, the IRP is applying machine learning, artificial intelligence, and a broad array of techniques to streamline computational processes for data transformation and make them more accessible. 

    “We are creating the Data Transformations IRP as a way to accelerate delivering the scientific value of data we gather here,” said Jay Bardhan, leader of EMSL’s Computation, Analytics, and Modeling science area. “The goal is to help everyone approach and access data pertaining to their experiments more easily.”

    As a Department of Energy (DOE) user facility, EMSL provides proposal call opportunities to researchers who, if awarded funding, have access to EMSL instrumentation and resources at no cost. EMSL is sponsored by DOE’s Biological and Environmental Research Program and is located on the campus of Pacific Northwest National Laboratory in Richland, Wash. 

    Learn more about this new IRP.

    Environmental Molecular Sciences Laboratory – EMSL

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  • Find the latest expert commentary on the recent U.S. Supreme Court decisions here

    Find the latest expert commentary on the recent U.S. Supreme Court decisions here

    This Thursday, the United States Supreme Court rejected affirmative action at colleges and universities around the nation, declaring that the race-conscious admissions programs at Harvard and the University of North Carolina were unlawful. Now on Friday, the Supreme Court decided to block the Biden administration’s student debt relief program and sided with a Christian web designer in Colorado who refuses to create websites to celebrate same-sex weddings out of religious objections. Despite their limited federal elected power, Conservatives have racked up more huge wins in the great political battles of the early 21st century.

    Newswise is your source for expert commentary. Below is a roundup of recent expert pitches concerning the United States Supreme Court.

    Sociologists Available to Discuss Affirmative Action Ruling in College Admissions

    – American Sociological Association (ASA)

    Law and diversity experts react to Supreme Court’s affirmative action decision

    – Tulane University

    Three important takeaways from SCOTUS decision in Groff v. DeJoy

    – University of Georgia

    SCOTUS decision on race-based admission: experts can comment

    – Indiana University

    U law expert available to comment on Supreme Court decision on affirmative action

    – University of Utah

    Recent SCOTUS decision puts to rest extreme 2020 presidential election claims, confirms state judicial input on states’ election rules

    – University of Georgia

     

     

    Newswise

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  • Revealing the power of citizen science for SDG advancement

    Revealing the power of citizen science for SDG advancement

    Newswise — The 17 SDGs are the blueprint to achieve a better and more sustainable future for all. They address the global challenges we face, including climate change, environmental degradation, and inequality. The achievement of the SDGs depends on the ability to accurately measure progress towards meeting the associated targets based on timely, relevant, and reliable data. Citizen science offers an innovative approach to complement and enhance official statistics. Additionally, citizen science can help raise awareness, mobilize action, and therefore achieve transformative change. 

    The collection brings together academic papers that offer insights into the contributions of citizen science to the SDGs and other international frameworks. The call for abstracts for this collection attracted 40 submissions, from which 21 papers were reviewed and accepted for publication. 

    “The interest in contributing to this collection reflects the importance and popularity of Citizen Science,” notes Dilek Fraisl, a researcher in the Novel Data Ecosystems for Sustainability Research Group of the Advancing Systems Analysis Program, who is leading the collection. “We received high-quality submissions from a diverse community, including citizen science researchers and practitioners, National Statistical Offices (NSOs), and international organizations, from both the Global North and South.” 

    Core themes that run across the set of diverse papers include monitoring and data collection, and the transformative potential of citizen science. The collection also reflects on the progress achieved in the scientific literature and through practical implementation over the past few years. 

    An example of a paper showcasing the potential of citizen science for monitoring the SDGs is the paper by Proden et al (2023), to which Fraisl contributed together with Linda See, who is also associated with the Novel Data Ecosystems for Sustainability Research Group at IIASA. 

    “This paper focuses on the views and experiences of the official statistics community, including representatives from NSOs, on citizen science data, along with the opportunities and challenges that these data present,” explains See. “Despite the widely recognized value of citizen science for monitoring the SDGs, we have discovered a conspicuous lack of awareness with this approach among members of the official statistics community.” 

    The collection serves as a comprehensive compilation, gathering the latest research, findings, and practical recommendations from a diverse set of actors. Additionally, it explores the development of this emerging field of study, providing a roadmap for future research and proposing tangible actions. It is worth noting that, even after eight years of pursuing the SDGs, nearly half of the 92 environmental SDG indicators still lack data. The collection demonstrates that citizen science has vast untapped potential for driving progress towards achieving the SDGs and other international frameworks, highlighting its capacity for collaborative problem solving. 

    “With this collection, we call for stronger cooperation between all citizen science actors, and for the Citizen Science Global Partnership (CSGP), to help bridge the gap between the citizen science and official statistics communities and stakeholders. We urge the official statistics community to consider the inclusiveness and relevance of their practices and encourage funders to reassess their strategies, to go beyond short-term pilot studies, and to provide genuine financial support to citizen science initiatives focused on monitoring and achieving sustainable development,” concludes Fraisl. 

    Note: Citizen Science: Theory and Practice is an international peer-reviewed journal focused on impacts and effective practices associated with public participation in scientific endeavors in all disciplines and across the globe. This open-access journal is a publication of the Citizen Science Association.

     

    References

    Fraisl, D., See, L., Campbell, J., Andrianandrasana, H., Danielsen, F. (2023). Special Collection: Contributions of Citizen Science to the SDGs and International Development Frameworks. Citizen Science: Theory and Practice https://theoryandpractice.citizenscienceassociation.org/collections/contributions-of-citizen-science

    Fraisl, D., See, L., Campbell, J., Danielsen, F., Andrianandrasana H. (2023). Editorial: The Contributions of Citizen Science to the United Nationals Sustainable Development Goals and Other International Agreements and Frameworks. DOI: https://doi.org/10.5334/cstp.643

     

     

    About IIASA: 

    The International Institute for Applied Systems Analysis (IIASA) is an international scientific institute that conducts research into the critical issues of global environmental, economic, technological, and social change that we face in the twenty-first century. Our findings provide valuable options to policymakers to shape the future of our changing world. IIASA is independent and funded by prestigious research funding agencies in Africa, the Americas, Asia, and Europe.

    International Institute for Applied Systems Analysis (IIASA)

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  • AI Could Replace Humans in Social Science Studies

    AI Could Replace Humans in Social Science Studies

    Newswise — In an article published yesterday in the prestigious journal Science, leading researchers from the University of Waterloo, University of Toronto, Yale University and the University of Pennsylvania look at how AI (large language models or LLMs in particular) could change the nature of their work.

    “What we wanted to explore in this article is how social science research practices can be adapted, even reinvented, to harness the power of AI,” said Igor Grossmann, professor of psychology at Waterloo. 

    Grossmann and colleagues note that large language models trained on vast amounts of text data are increasingly capable of simulating human-like responses and behaviours. This offers novel opportunities for testing theories and hypotheses about human behaviour at great scale and speed. 

    Traditionally, social sciences rely on a range of methods, including questionnaires, behavioral tests, observational studies, and experiments. A common goal in social science research is to obtain a generalized representation of characteristics of individuals, groups, cultures, and their dynamics. With the advent of advanced AI systems, the landscape of data collection in social sciences may shift.

    “AI models can represent a vast array of human experiences and perspectives, possibly giving them a higher degree of freedom to generate diverse responses than conventional human participant methods, which can help to reduce generalizability concerns in research,” said Grossmann.

    “LLMs might supplant human participants for data collection,” said UPenn psychology professor Philip Tetlock. “In fact, LLMs have already demonstrated their ability to generate realistic survey responses concerning consumer behaviour. Large language models will revolutionize human-based forecasting in the next 3 years. It won’t make sense for humans unassisted by AIs to venture probabilistic judgments in serious policy debates. I put an 90% chance on that. Of course, how humans react to all of that is another matter.”

    While opinions on the feasibility of this application of advanced AI systems vary, studies using simulated participants could be used to generate novel hypotheses that could then be confirmed in human populations.

    But the researchers warn of some of the possible pitfalls in this approach – including the fact that LLMs are often trained to exclude socio-cultural biases that exist for real-life humans. This means that sociologists using AI in this way couldn’t study those biases.

    Professor Dawn Parker, a co-author on the article from the University of Waterloo, notes that researchers will need to establish guidelines for the governance of LLMs in research.

    “Pragmatic concerns with data quality, fairness, and equity of access to the powerful AI systems will be substantial,” Parker said. “So, we must ensure that social science LLMs, like all scientific models, are open-source, meaning that their algorithms and ideally data are available to all to scrutinize, test, and modify. Only by maintaining transparency and replicability can we ensure that AI-assisted social science research truly contributes to our understanding of human experience.”

    University of Waterloo

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  • Sylvester study identifies ‘marked disparities’ in federal cancer research funding

    Sylvester study identifies ‘marked disparities’ in federal cancer research funding

    Newswise — MIAMI, FLORIDA (EMBARGOED UNTIL JUNE 8, 2023) – A research team at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine compiled and analyzed statistics from federal cancer research funding sources and found that funds tend to be allocated more heavily toward cancers that occur more often in non-Hispanic white people than in other racial and ethnic groups.

    The study found that funding across cancer sites is not concordant with lethality and that cancers with high incidence among racial/ethnic minorities receive lower funding, but the study’s authors say addressing these inequities could make a difference in cancer research disparities within a short time.

    “The results of this study are immediately actionable,” said Dr. Shria Kumar, a Sylvester gastroenterologist and the senior author of a paper in the June 8 Journal of the National Cancer Institute. “Agencies can evaluate their own recent funding distributions and those for upcoming cycles, then they can prioritize funding for cancers that disproportionately impact minorities to mitigate disparities and reduce cancer burden.”

    The authors analyzed federal funding data to determine correlations between funding directed to cancer incidence and funding aimed at cancer mortality. They focused on National Cancer Institute funding for the 19 most common cancers, considering their respective “public health burdens,” a term that includes the incidence rate of the disease, the mortality rate, and person-years of life lost.

    Although previous studies of funding distribution have evaluated these three factors separately, the Sylvester team evaluated funding using a validated measure – funding-to-lethality (FTL) scores – that incorporates all three metrics and provides a composite, objective perspective on disease burden.

    “We were very surprised that correlation was stronger for incidence than mortality. It shows how complex and multifaceted funding allocation is, but it really underlines the need to look at it objectively, as we did here, and use it as a tool to mitigate cancer disparities, a common goal,” Kumar said.

    Breast and prostate cancer had the highest and second-highest FTL scores, while esophagus and stomach cancer ranked 18th and 19th. Kumar and colleagues noted that breast cancer research received approximately 50 times more funding than stomach cancer in 2018, even though estimated breast cancer deaths were only four times those of stomach cancer deaths.

    The authors also cited previously published statistics showing that cancers more frequently affecting non-Hispanic white people – such as breast cancer, leukemia and lymphoma – receive more funding than cancers with high incidence rates among racial and ethnic minorities – such as stomach, uterine and liver cancers.

    “In my research and in clinical practice, disparities in cancer are an unfortunate but well-known entity. I’m a gastroenterologist, and disparities are of paramount concern in my areas of expertise – stomach and colorectal cancer,” Kumar said. “Racial and ethnic disparities are well documented across the spectrum of cancer types, and this is of utmost importance. The White House’s Cancer Moonshot initiative has a focus on mitigating cancer disparities, and the NCI is very attuned to the impact that disparities have on our quest to improve cancer burden.”

    Specifics from the study:

    • There was a stronger correlation between FTL scores and race/ethnicity-specific cancer incidence, rather than mortality.
    • There was strong correlation between a cancer’s incidence among non-Hispanic white people and its FTL score, but this was not the case for other racial/ethnic groups, where there was only a weak to moderate correlation.
    • There was a moderate to strong correlation between a cancer’s mortality among non-Hispanic white people and its FTL score, but there was only a weak correlation for all other racial/ethnic groups.

    For the study, Kumar and her team obtained data from the NCI’s Surveillance, Epidemiology and End Results (SEER) database, the United States Cancer Statistics (USCS) database, and Funding Statistics between 2014 and 2018. For each year, they identified the incidence rate and mortality rate – both overall and by race/ethnicity – per 100,000 people for the 19 most common cancer sites, as well as NCI funding for each cancer.

    “Despite initiatives to bolster cancer research funding and to mitigate disparities in cancer outcomes, there are marked disparities in federally funded cancer research that do not correlate with lethality,” the authors said. “Our paper identifies discrepancies in funding by demographic groups and highlights the need to ensure that federal funds are equitably distributed. This is especially important given the discrepancies in cancer outcomes for minorities, particularly in the more underfunded cancers.”

    Additional authors: Dr. Shida Haghighat is the study’s first and corresponding author. Co-authors include Dr. Chunsu Jiang, Dr. Wael El-Rifai, Alexander Zaika, and Dr. David S. Goldberg. All authors are affiliated with the University of Miami Miller School of Medicine or Sylvester Comprehensive Cancer Center and the University of Miami Health System.

    Funding: Dr. Haghighat is supported by a National Institutes of Health training grant, T32 DK 116678-05.

    Disclosures: The authors declare no personal, professional or financial conflicts of interest.

    Journal: Journal of the National Cancer Institute: Urgent Need to Mitigate Disparities in Federal Funding for Cancer Research.

    DOI: https://doi.org/10.1093/jnci/djad097

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    PHOTO CAPTION/CREDIT:

    “Racial and ethnic disparities are well documented across the spectrum of cancer types, and this is of utmost importance,” said Dr. Shria Kumar. “The White House’s Cancer Moonshot initiative has a focus on mitigating cancer disparities, and the NCI is very attuned to the impact that disparities have on our quest to improve cancer burden.” Photo by Sylvester

    # # #

    MEDIA CONTACT:
    Sandy Van
    [email protected]
    808.206.4576

     

    Sylvester Comprehensive Cancer Center

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  • Newly Elected Council Representatives Named for CUR’s 2023-2024 Executive Board

    Newly Elected Council Representatives Named for CUR’s 2023-2024 Executive Board

    Newswise — John F. Barthell, Ph.D. (University of Central Oklahoma/National Science Foundation), Lance Barton, Ph.D. (Austin College/University of North Carolina at Charlotte), and Winny Dong, Ph.D. (California State Polytechnic University – Pomona) have been elected to serve as council representatives on CUR’s Executive Board. These positions assist in providing the strategic direction of CUR and represent the voice of its members while supporting CUR’s mission and strategic goals.  

    John Barthell is currently a program officer at the National Science Foundation. Barthell previously held the position of general representative on CUR’s Executive Board as well as a councilor in the At-Large Division since 2011. Barthell has continued his commitment to CUR by also participating as a consultant on the CUR Transformations grant. These many leadership roles allowed Barthell to not only grow and expand his sense of relevance of the value of CUR but advance his ability to understand and practice leadership for undergraduate research within the community.

    “I am honored to serve in this leadership role with CUR and to expand my involvement with student-centered education from my previous work at the University of Central Oklahoma to now include this important service at the national level,” explained Barthell.

    Charlotte Simmons, provost for the University of Central Oklahoma stated “With this honor, Dr. Barthell will continue to intensify his career-long commitment to undergraduate education and the value of preparing students for their chosen career paths. The University of Central Oklahoma is proud to see him receive this very deserved recognition.”

    Lance Barton is currently a professor and chair of the Biology department at Austin College who will continue on with the University of North Carolina at Charlotte in June 2023. Much of his career has been focused on the creation and development of an effective training program for undergraduates through research. Barton has served as a councilor in the CUR Biology Division for 10 years having had the pleasure of collaborating with colleagues across the continent to enhance the quantity and quality of student research opportunities by sharing knowledge and best practices.

    “CUR Councilors helped mentor me from early in my career. For the past decade, I’ve been excited to volunteer and help support other faculty. Joining the CUR Executive Board is an exciting next step for me in helping the organization continue to improve services for members and students,” explains Barton.

    Winny Dong is the faculty director at the Office of Undergraduate Research at California State Polytechnic University -Pomona (Cal Poly Pomona). With multiple honors, including the US Presidential Award for Excellence in Science, Mathematics, and Engineering Mentoring (2021), Dong was re-elected to serve as a returning Engineering Division Councilor for CUR. At Cal Poly Pomona, Dong founded the Office of Undergraduate Research in 2013 and has served as its faculty director since its inception. Her experience in supporting undergraduate research is one directly connected to supporting students from first-generation, low-income, and traditionally under-represented communities and populations. Based on what she has learned by supporting diverse students and creating an inclusive environment, her goal is to bring that perspective to board discussions in developing a culture and community that actively prioritizes diversity, equity, and inclusion.

    Dong states, “I am proud to be a part of an organization that is dedicated to advocating for and supporting undergraduate research. I am committed to working with my fellow board members to ensure that CUR continues to provide impactful leadership in undergraduate research.”

    “We are proud to have Dr. Winny Dong represent Cal Poly Pomona on the Executive Board for CUR. Winny is a passionate advocate for undergraduate research, and her work on the board will help to ensure that all students have the opportunity to participate in this transformative experience. As a vital part of a well-rounded education, Cal Poly Pomona is committed to providing students with the opportunity to gain hands-on experience in their field of study, to develop critical thinking and problem-solving skills, develop their communication and presentation skills, and to network with faculty and other professionals in their field,” explained Dr. Olukemi Sawyerr, associate vice president for academic Innovation at Cal Poly Pomona.Lindsay Currie, CUR executive officer, stated: “We are excited to see the executive board continue to grow with such leaders and impressive individuals. As we continue to navigate the future of CUR, it is imperative for the association leadership to be thoughtful, nimble, and steadfast. These leaders have all of that and more. These individuals all hold a passion for CUR that will help in achieving CUR’s mission to advance undergraduate research.”

     

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    Founded in 1978, the Council on Undergraduate Research (CUR) focuses on providing high-quality and collaborative undergraduate research, scholarly, and creative activity. Among the many activities and networking opportunities that CUR provides, the organization also offers support for the professional growth of faculty and administrators through expert-designed institutes, conferences, and a wide-range of volunteer positions. The CUR community, made up of nearly 700 institutions and 13,000 individuals, continues to provide a platform for discussion and other resources related to mentoring, connecting, and creating relationships centered around undergraduate research. CUR’s advocacy efforts are also a large portion of its work as they strive to strengthen support for undergraduate research. Its continued growth in connections with representatives, private foundations, government agencies, and campuses world-wide provides value to its members and gives voice to undergraduate research. CUR is committed to inclusivity and diversity in all of its activities and our community.

    CUR focuses on giving a voice to undergraduate research with learning through doing. It provides connections to a multitude of campuses and government agencies, all while promoting networking and professional growth to its community.

    Council on Undergraduate Research (CUR)

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  • Gun Violence: Can Research Help?

    Gun Violence: Can Research Help?

    Newswise — The problem of gun violence in America can at times seem utterly intractable.

    The horrific frequency of mass shootings (almost 300 in the first six months of 2022, according to the Gun Violence Archive), the tragic daily toll of firearm-related deaths (124 per day on average, according to the CDC), and the inability of politicians to implement effective gun control measures have had devastating personal consequences for individuals and families and pose a significant public health challenge for the nation.

    The CDC reports that firearm-related injuries rank among the five leading causes of death for people ages 1 to 44 and are now the leading cause of death for children and adolescents, killing more people ages 1 to 19 than car accidents, drug overdoses, or cancer.

    But for epidemiologist and gun violence expert Charles Branas, PhD, the Gelman Professor of Epidemiology and chair of the Department of Epidemiology in the Mailman School of Public Health, the scope and recalcitrance of the problem only heighten the urgency of answering one basic question: “What do you do about it?”

    Toward that end, in 2020 Dr. Branas helped launch the Columbia Scientific Union for the Reduction of Gun Violence, or SURGE, a coalition of faculty, students, and alumni from across the university dedicated to finding creative scientific solutions to gun violence.

    The need for such interventions is especially pressing given the difficulty of enacting gun control at the state and national levels, despite research by Dr. Branas and others showing that stricter gun control laws do in fact reduce gun violence. (The bipartisan gun safety legislation passed by Congress in June supports some existing evidence-based measures, but in limited fashion.)

    Efforts to find solutions have been hindered by a lack of government funding for scientific research into gun violence. Federal funding dried up in 1996 after Congress passed the Dickey Amendment, which barred the CDC, and later the NIH, from spending money to promote gun control and dissuaded many young scientists from pursuing careers in gun violence research.

    Recently, however, SURGE and other groups persuaded Congress to renew federal funding. And Dr. Branas hopes that fresh grants from the CDC and the NIH, coupled with opportunities for networking and collaboration provided by SURGE, will encourage a new generation of researchers to develop innovative, evidence-based interventions to prevent gun violence. 

    Dr. Branas sees signs that this is already happening.

    Junior faculty, including Ashley Blanchard, MD, a pediatric emergency physician at VP&S, are investigating novel interventions with the support of fellow SURGE members. And the coalition is helping senior faculty like Dr. Branas and Paul Appelbaum, MD, the Elizabeth K. Dollard Professor of Psychiatry, Medicine and Law, engage with like-minded colleagues from a variety of disciplines. Other SURGE members are from Columbia’s schools of law, nursing, and social work and from Teachers College and Barnard College.

    “I remember walking into the room during our first meeting and just being in awe that there was this larger campus consortium of people interested in doing this type of work,” says Dr. Blanchard, assistant professor of pediatrics (in emergency medicine). “As a junior investigator, I can’t navigate the path to a firearm-related research career without having that mentorship. Having that room, and those groups of people, has really been incredible.”

    DEEP ROOTS

    If SURGE represents a new path to novel solutions to gun violence, it builds on decades of work by VP&S physicians. SURGE member Danielle Laraque-Arena, MD, a pediatrician and professor of clinical epidemiology and pediatrics at the Mailman School and VP&S, helped pioneer place-based gun violence interventions while working at Harlem Hospital from 1986 to 2000, a period that coincided with a national spike in gun violence.

    During that time, Dr. Laraque-Arena and Barbara Barlow, MD, then chief of pediatric surgery at Harlem Hospital, partnered with city agencies and community members to reduce injury rates among children and adolescents in central Harlem.

    Data collected through the Northern Manhattan Injury Surveillance System, a population-based survey developed by the Mailman School to tally severe injuries, indicated that adolescents represented 89% of gun-related deaths. Many of the deaths involved unintentional firearm injuries or individuals caught in crossfire, and the vast majority of fatalities occurred before hospitalization, which suggested that only prevention could significantly reduce firearm fatalities among young people in the area. 

    Dr. Laraque-Arena and her colleagues focused on implementing programs designed to create safe spaces and activities for children and adolescents, including several locations that involved rehabilitating and greening public spaces such as parks and playgrounds. The goal was to reduce the risk of intentional and unintentional injuries alike; an analysis showed that such broad-based, environment-oriented projects did significantly reduce firearm injuries.

    Decades later, Dr. Branas tested the power of place-based interventions through citywide experiments conducted in Philadelphia, Detroit, and New Orleans. Among other things, he and his colleagues showed that rehabilitating abandoned buildings and vacant lots, which function as storage lockers for illegal firearms, can reduce gun violence by as much as 39%.

    Dr. Branas is in talks with the parks department and other city agencies to bring similar programs to New York City. Together with SURGE member Sonali Rajan, PhD, an associate professor of health education at Teachers College, Dr. Branas leads a nationwide case-control study of firearm violence prevention tactics and policies in K-12 schools. The study, which is funded by the NIH, will examine 650 schools, comparing the safety measures (metal detectors, active shooter drills, armed school personnel) in place at schools that have experienced shootings with those that have not.

    RIGOROUS SCIENTIFIC APPROACH

    Dr. Appelbaum, who has for many years explored the relationship among mental health, gun violence, and gun policy, and Dr. Blanchard bring a similarly rigorous scientific approach to understanding—and preventing—gun violence.

    In a series of studies examining the relationships among gun ownership, gun violence, and mental illness, Dr. Appelbaum has debunked the notion, often floated by politicians in the wake of mass shootings, that such events can be prevented by addressing serious mental illness.

    “As human beings, we have a natural inclination when we see an act that is incomprehensible to assume that the person who did it must be, in lay terms, crazy,” Dr. Appelbaum says. The data suggest that most of those who commit these acts are not mentally ill. “They’re angry, they’re isolated, they’re frustrated, but they are not suffering from psychosis or other severe mental disorders.”

    Dr. Appelbaum points out that the situation is different for suicide. Depression, substance use, and other mental disorders are strong risk factors for self-harm. As a result, efforts to identify and treat people suffering from such disorders can indeed prevent suicides if done effectively.

    Nonetheless, he says, the most effective way to prevent gun violence, whether directed at others or at oneself, is to limit access to firearms.

    REDUCING ACCESS

    Measures aimed at keeping guns out of the hands of high-risk groups include red flag laws that allow the authorities to temporarily confiscate firearms from individuals who represent a threat to themselves or others; safe storage options, such as gun safes and trigger locks; and child access prevention laws that penalize adults for failing to store firearms safely and allowing children access to them.

    Such measures have been shown to reduce firearm injuries and deaths and could play a particularly important role in preventing suicides. Studies show that most people who attempt suicide do so on impulse, moving from decision to action in less than an hour.

    “There’s good evidence to show that especially in adolescents, the transition from contemplating suicide to action is very short-lived and transient and therefore utilizes whatever means are easily available,” Dr. Blanchard says. 

    The extraordinary lethality of guns means that someone who decides to commit suicide and has access to a firearm is much more likely to succeed than someone who does not. Research indicates that acts of suicide involving a firearm are fatal 90% of the time, compared with 13.5% for self-poisoning.

    “The gun doesn’t give you a second chance,” says Dr. Laraque-Arena.

    As a result, taking firearms out of the equation immediately reduces the likelihood that a suicide attempt will succeed. In keeping with that logic, Dr. Blanchard is conducting a pilot feasibility study of a tablet-based tool called Lock and Protect intended to increase safe storage or removal of guns and other lethal means by parents whose adolescents are at increased risk of suicide.

    The tool is being studied in the pediatric emergency department at NewYork-Presbyterian’s Morgan Stanley Children’s Hospital, where Dr. Blanchard and her colleagues often see patients who engage in predictors of suicide such as suicidal ideation and self-harm. The primary goal of the study, which involves experts from the departments of emergency medicine and psychiatry and the Irving Institute for Clinical and Translational Research’s Implementation Science Initiative, is to determine the feasibility of implementing the tool and expanding a trial for a larger emergency department population.

    Patients and their parents enroll in the study together. The tool evaluates suicide risk using questionnaires such as the Columbia Suicide Severity Rating Scale and guides parents through the process of identifying the lethal means in their homes (guns, medications, ligatures) and understanding how they can best keep their children safe.

    The tool was designed to take into consideration factors such as the cost of safe storage and the values of parents, including those who feel strongly about gun ownership. At tool completion, a safety plan is provided to parents to implement at home. Dr. Blanchard and her team follow up with parents at two weeks and with patients and parents at four weeks, with the long-term objective of understanding if the tool helps change home storage of guns and other lethal means.

    Lock and Protect is precisely the kind of innovative gun violence intervention that Dr. Branas hoped SURGE would produce, and he is certain that more will be developed as the coalition continues to grow.

    “We are two years into this,” he says. “We’ve done quite a bit, but we’re still building.”

    Columbia University College of Physicians & Surgeons

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  • Study warns of underestimated uncertainty in published research

    Study warns of underestimated uncertainty in published research

    Newswise — New research involving the University of Sydney Business School has found researchers underestimate the degree of uncertainty in their findings.

    In empirical science, researchers analyse samples to test hypotheses, and this creates a within-researcher variation due to sampling error. Re-sampling yields different values of the estimator, and the standard deviation of this distribution is referred to as standard error.

    Researchers are less aware, however, that there is an additional level of uncertainty due to there not being a standard analysis path.

    Researchers vary in what they deem to be the most reasonable path, and estimates may vary across researchers as they might pick different paths. This is referred to a non-standard error.

    The study, led by Professor Albert Menkveld at the Vrije University of Amsterdam and nine other academics, involved 164 teams testing the same hypotheses on the same data to measure the impact of non-standard errors.

    A separate team of highly experienced researchers was engaged to peer review the work of each of the 164 teams.

    The research, to be published in the Journal of Finance, found that such non-standard errors were substantial and similar in magnitude to standard errors.

    A relatively straightforward hypotheses about market share produced a non-standard error rate of 1.2 percent. For a more complex hypothesis about market efficiency, the non-standard error rate was up at 6.7 percent.

    Non-standard errors were smaller for better reproducible or higher-rated research, and slashed in half by adding peer-review stage.

    Study participant Professor Joakim Westerholm from the University of Sydney Business School said the research highlights the importance of researchers taking into account the potential dispersion in estimates when testing hypotheses due to the researchers’ choice of analysis path.

    “If researchers are not aligned on key decisions, such as selecting a statistical model or treating outliers, their estimates are likely to differ – adding uncertainty to the estimate reported by a single team,” Professor Westerholm said.

    “This type of uncertainty is often underestimated by researchers, which is why we need to be aware of our own bias and the steps we can take to minimise its impact.

    “While we cannot expect every question to be investigated by a team of 160 seasoned research teams, we can design approaches that take non-standard errors into account – for example, each member of a team could perform independent tests that are then compared and evaluated.”

    Professor Westerholm said the next stage in the research may be to replicate the study using artificial intelligence and machine learning to see whether this has any impact on the rate of non-standard errors.

     

    Declaration

    The coordinators are grateful for financial support from the Knut and Alice Wallenberg Foundation, the Marianne, Marcus Wallenberg Foundation, the Jan Wallander, Tom Hedelius Foundation, FWF grant P29362, FWF grant SFB F63, Riksbankens Jubileumsfond grant P21-0168, and NWO-Vici.

    University of Sydney

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  • Mining the Gap

    Mining the Gap

    More and more students are graduating with their bachelor’s degrees and taking a gap year, a period of time before jumping into a postgraduate program. A new grant from the American Cancer Society will help the UNM Comprehensive Cancer Center introduce these students to scientific research.

    University of New Mexico Comprehensive Cancer Center

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  • Democracy depends on the freedom of the press: The latest news on media and journalism

    Democracy depends on the freedom of the press: The latest news on media and journalism

    “Freedom of the press is not just important to democracy, it is democracy.”

    -Walter Cronkite

    According to the Pew Research Center, more than eight-in-ten U.S. adults (86%) say they get news from a smartphone, computer or tablet. Americans say they prefer a digital platform – whether it is a news website (26%), search (12%), social media (11%) or podcasts (3%).* Traditional media remain important even for those people with the most gadgets. However, social media and non-traditional outlets are rising as the main source of how people stay informed. According to a report from the BBC, Instagram is the most popular news source among younger people.

    In this information age, it’s vital to have an open conversation on how the message is delivered. 

    Here are some of the latest stories in the Media and Journalism channel on Newswise. For a more in-depth look at social media issues, check out the Social Media channel.

    Newswise Live Event for March 15: What can we expect from AI and Chatbots in the next few years? 

    (How AI is transforming journalism)

    Study finds political campaigns may change the choices of voters – but not their policy views

    Researchers’ Model for TV Ad Scheduling Reaps Revenue Increase for Networks

    What distinguishes fans from celebrity stalkers?

    The claim that U.S. temperatures are not trending upward is false

    We cannot predict earthquakes with accuracy, despite claim

    Fact-checking the reporting of the explosion in East Palestine, Ohio

    Cinema has helped ‘entrench’ gender inequality in AI

    Experts split on ‘prebunking’ – shifting blame or empowering users?

    Geography, language dictate social media and popular website usage, study finds

    ChatGPT can (almost) pass the US Medical Licensing Exam

    Tweets reveal where in cities people express different emotions

    War tourists fighting on a virtual front, since Ukraine-Russia war

    Media literacy is an important tool in training police officers

    COVID-19 conspiracy theories that spread fastest focused on evil, secrecy

    How do news audiences respond to disclosures of preprint status?

    It isn’t what you know, it’s what you think you know

     

     

    Newswise

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  • Newswise Live Event for March 15: What can we expect from AI and Chatbots in the next few years?

    Newswise Live Event for March 15: What can we expect from AI and Chatbots in the next few years?

    What: What can we expect from AI and Chatbots in the next few years? A Newswise Live Event

    When: Wednesday, March 15, 2023, 1 PM to 2 PM EST

    Who: Expert Panelists include:

    • Sercan Ozcan, Reader (Associate Professor) in Innovation & Technology Management at the University of Portsmouth
    • Jim Samuel, Associate Professor of Practice and Executive Director, Master of Public Informatics at the Bloustein School, Rutgers-New Brunswick
    • Alan Dennis, Professor of Information Systems and the John T. Chambers Chair of Internet Systems in the Kelley School of Business at IU Bloomington

    Details: Artificial intelligence news has escalated considerably in the last few months with the roll-out of Microsoft’s Bing Chatbot and the popularity of large language models (LLMs) such as ChatGPT. Popular social media app Snapchat has launched its chatbot called “My AI,” using the latest version of ChatGPT. Newswise Live is hosting a live expert panel on what to expect from AI in the near future, its impact on journalism, and the corporate race for AI dominance (Google vs. Microsoft, etc.). Panelists will discuss what we can expect from AI and Chatbots in the next three years.

    MEDIA REGISTER HERE

    Attention Journalists and Editors:

    A video and transcript of the event will be sent to those who register shortly after the event. Even if you can’t make this live virtual event, we encourage you to register to get a copy of these materials.

     

    Newswise

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  • Rutgers Researchers to Study the Impact of Multiple Health Conditions on Medication Outcomes in Older Adults

    Rutgers Researchers to Study the Impact of Multiple Health Conditions on Medication Outcomes in Older Adults

    Newswise — The National Institutes of Health has awarded Rutgers a $3.5 million grant to conduct a five-year study exploring the impact medications have on older adults with multiple medical conditions.

    The goal of researchers from Rutgers Center for Pharmacoepidemiology and Treatment Science (PETS) is to provide patients with multiple chronic conditions, caregivers and health care providers with information needed to make informed treatment decisions.

    “Unfortunately, most clinical trials of medications do not include patients with multimorbidity, which means that there is little data available about the risks and benefits of medications in this population,” said Chintan Dave, assistant director at PETS and the principal investigator of the National Heart, Lung and Blood Institute grant-backed project. “This lack of information makes it difficult for health care providers to make informed decisions about treating patients with multiple medical conditions.”

    Multimorbidity is a common issue for older adults, according to researchers. In the U.S., more than two thirds of adults over the age of 65 have multiple chronic conditions, which can lead to higher health care costs and increased risk of negative health outcomes, including death.

    “With over 36 million older adults in the U.S. affected by multimorbidity, this is a pressing issue that requires immediate attention,” said Dave, who also is a core faculty member of the Rutgers Institute for Health, Health Care Policy and Aging Research (IFH) and an assistant professor with Rutgers Ernest Mario School of Pharmacy.

    Dave and his colleagues will use data from more than 23 million patients to learn how having multiple conditions affects the benefits and risks of medications, representing the first effort to systematically evaluate the impact of multimorbidity on medication related outcomes. Specifically, researchers will examine medication use and outcomes in three highly prevalent chronic conditions: Type 2 diabetes, atrial fibrillation and atherosclerotic cardiovascular disease.

    Coinvestigators involved in the study include Brian Strom, the chancellor of Rutgers Biomedical and Health Sciences; Tobias Gerhard, interim director of IFH and director of PETS; Jason Roy, a professor of biostatistics and chair of the Department of Biostatistics and Epidemiology at the Rutgers School of Public Health; Soko Setoguchi, a core faculty member at PETS and IFH, professor of medicine at Rutgers Robert Wood Johnson Medical School and professor of epidemiology at Rutgers School of Public Health; and Melissa Wei, an assistant professor of medicine in residence at the David Geffen School of Medicine at University of California, Los Angeles.

    The grant was supported by the National Heart, Lung, And Blood Institute of the National Institutes of Health under Award Number R01HL163163. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

    Rutgers University-New Brunswick

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  • ASU ranks in top 10 for inventions, patents, licenses and startups among universities without medical schools

    ASU ranks in top 10 for inventions, patents, licenses and startups among universities without medical schools

    BYLINE: Michelle Stermole, Senior Director, Public Relations and Strategic Communications, ASU Enterprise Partners

    Arizona State University ranks among the top 10 research institutions without a medical school for inventions disclosed, U.S. patents secured, license and option deals closed and startups launched, according to the Association of University Technology Managers‘ latest survey of 147 reporting institutions on licensing activities at U.S. and Canadian universities, hospitals and research institutions. 

    ASU, California Institute of Technology, Massachusetts Institute of Technology and North Carolina State University were the only universities that ranked in the top 10 across all four categories among institutions without medical schools. 

    In fiscal year 2021, ASU ranked higher than the previous fiscal year for three of the four key metrics among its peer group of institutions without medical schools, according to AUTM’s survey data. ASU rose one spot to third for U.S. patents issued, rose one spot to second for startups launched and rose two spots to seventh for license and option deals closed. It remained fifth for inventions disclosed, compared to fiscal year 2020.  

    Innovations from researchers in the Ira A. Fulton Schools of Engineering and the Biodesign Institute significantly boosted ASU’s results. 

    “ASU continues to excel in these performance indicators because its commitment to innovation and real-world impact is woven into the very fabric of its charter and is exemplified by its leaders,” said Kyle Siegal, senior vice president and chief patent counsel for Skysong Innovations. 

    Skysong Innovations, ASU’s exclusive technology transfer and intellectual property management organization, helps translate research into impact by protecting intellectual property developed in ASU labs and negotiating licensing deals with commercial partners who advance the technologies and develop solutions for society.

    The organization, fueled by ASU’s growing research enterprise, has cumulatively secured more than 1,400 U.S. patents for ASU and closed nearly 1,400 license or option deals with commercial partners during its years of service to ASU. Skysong Innovations has also facilitated more than 200 ASU startups that have collectively attracted more than $1.2 billion in external funding. 

    “One of our strengths as a university is reflected in ASU’s ability to facilitate research discoveries into startups — an area of growth that represents our commitment to the overall health of our local and national communities,” said Sally C. Morton, executive vice president of ASU’s Knowledge Enterprise. “Innovation at this speed and scale requires the ability to change the way we look at and solve problems; it takes commitment, teamwork, entrepreneurship, and community engagement, and ASU continues leading the way.”

    During fiscal year 2021, ASU had 301 invention disclosures, which is an innovation submitted by an ASU researcher for potential commercialization.

     

    ASU startups seek to solve global challenges

    FY21 saw the birth of new startups across a broad spectrum of sectors including biotech, solar energy and software.

    • GELF Energy was among the 21 ASU startups established in FY21. The company is developing microbial technologies that process food and sewage waste streams into transportable hydrogen gas for the maritime and transportation sectors. The technologies were invented by John Sabo, former ASU professor in the Global Institute of Sustainability and Innovation; Bruce Rittmann, a professor and director of the Biodesign Swette Center for Environmental Biotechnology; and Cesar Torres, a professor in the School for Engineering of Matter, Transport and Energy. 
    • Lifelab Studios is developing an online learning platform that connects learners in small communities to support each other as they use learning to achieve real-world goals. The platform was created by a team of researchers, programmers and artists, includingSasha Barab, a professor in theSchool for the Future of Innovation in Society and in the Mary Lou Fulton Teachers College and executive director of the Center for Games and Impact.
    • SunFlex Solar is developing high-efficiency interdigitated back-contact solar panels. The company was co-founded byKate Fisher, an assistant research technologist at theSchool of Electrical, Computer and Energy Engineering; Zachary Holman, an associate professor in the School of Electrical, Computer and Energy Engineering and director of faculty entrepreneurship in the Ira A. Fulton Schools of Engineering; Zhengshan “Jason” Yu, a research assistant professor, School of Electrical, Computer and Energy Engineering; and graduate research associate Barry Hartweg.
    • VaxSyna Inc. is another ASU startup established in FY21. The company is developing low-cost vaccines and therapeutics that can be easily modified to combat various pathogens associated with global health challenges. The technology was invented by Hugh Mason, an associate professor in the Biodesign Center for Immunotherapy, Vaccines and Virotherapy, and Mary Pardhe, an academic associate.

     

    Patented technologies advance early detection of neurological conditions

    There were 157 U.S. patents issued for ASU technologies during the period, and 81 licenses and option deals closed during that time.

    In October 2020, Skysong Innovations secured for ASU a patent exclusively licensed to Aural Analytics that covers the use of a patient’s speech to detect and track neurological conditions including Parkinson’s disease, amyotrophic lateral sclerosis, Huntington’s disease, multiple sclerosis, traumatic brain injury, stroke and other conditions where motor speech changes may occur.

    Aural Analytics, a venture-backed ASU spinout company, has built applications that use speech to detect subtle changes in brain health. The company was co-founded by Julie Liss, associate dean and professor in the College of Health Solutions, and Visar Berisha, an associate professor with a joint appointment in the College of Health Solutions and the School of Electrical, Computer and Energy Engineering.

    Arizona State University (ASU)

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  • Brookhaven HSRP and SPARK Program Alumni Selected in 2023 Regeneron Science Talent Search

    Brookhaven HSRP and SPARK Program Alumni Selected in 2023 Regeneron Science Talent Search

    Newswise — Last month, Society for Science (the Society) announced the 300 scholars in the Regeneron Science Talent Search 2023. The scholars were each awarded $2,000 and also awarded $2,000 for their school. Scholars were chosen based on their research, leadership skills, community involvement, commitment to academics, creativity in asking scientific questions, and promise as STEM leaders, demonstrated through the submission of their original, independent research projects, essays and recommendations (See the full list of this year’s scholars).

    Two of this year’s scholars were not only students from high schools on Long Island, but also young researchers who participated in two of the intensive educational programs offered at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory. Having the hands-on experience of working in a busy laboratory environment, seeing their research being carried out, and collaborating with experts in their fields of interest was a big asset in applying to a competition of this caliber.

    “These programs provide students with an authentic research experience,” said Aleida Perez, Interim Manager of University Relations and Workforce Development for Teachers and Scientists (WDTS) and DOE Programs at Brookhaven Lab. “They are able to develop their scientific skills and build a collaborative network for their future educational, and perhaps professional, paths.”

    Jack Shultz, a student at Westhampton Beach high school, was part of the Student Partnerships for Advanced Research and Knowledge (SPARK) Program at Brookhaven Lab last year. In this program, high school students and their science educators become visiting researchers with access to Brookhaven National Laboratory’s scientific facilities. Shultz has a core interest in biology and chemistry, which has led to several research projects and more specific areas of interest.

    “Living on Long Island, it’s easy to take for granted what a unique and incredible environment we have,” said Shultz. “In a short amount of time, you can actually see climate change effects firsthand in things like marine ecosystems or the change in local weather patterns.”

    Shultz has been researching kelp ecosystems on Long Island using the SRX and XPD beamlines at the Lab’s National Synchrotron Light Source II—a U.S. Department of Energy (DOE) Office of Science user facility—under the mentorship of Juergen Thieme, science coordinator for the imaging & microscopy program at NSLS-II and Eric Dooryhee, program manager for the Hard X-ray Scattering and Spectroscopy (HXSS) program at NSLS-II.

    “The scientists at the beamlines were so helpful and inclusive,” recalled Schultz. “Their willingness and enthusiasm really pushed the boundaries of my work. Eric and Juergen were so encouraging and informative. There are people here with two doctorates, but they treat high school students like peers. It’s amazing that we have a resource like this locally, and many people may have research ideas that could benefit from it but have no idea it exists or that there are pathways to access it.”

    His experience applying and being selected as a Regeneron scholar and being able to experience what it’s like to do research in a national laboratory setting as part of a team of professional scientists has only reaffirmed Shultz’s enthusiasm for science. He plans to continue his current research and pursue a degree in molecular biology.

    Marc Nichitiu is a high school senior at the Stony Brook School that participated in the lab’s 2022 High School Research Program (HSRP). This competitive six-week program allows high school juniors and seniors to collaborate on a research project with Brookhaven Laboratory staff. Nichitiu was mentored by Igor Zaliznyak, a scientist specializing in Neutron Scattering in Brookhaven Lab’s Condensed Matter Physics and Materials Science Department. Zaliznyak was not only an encouraging mentor, but his advice was also one of the reasons Nichitiu entered the Regeneron competition.

    “At first, I thought that I didn’t really have the time to apply for the scholarship and I simply wanted to focus on my research,” recalled Nichitiu, “but Dr. Zaliznyak really liked the research I was doing and encouraged me to write it up. It’s good practice, in general, to be able to describe what you’ve been doing and explain it to others. Indeed, just the experience of applying was helpful.”

    Nichitiu collaborated with Zaliznyak to characterize the scattering signature of superfluid helium using thermal neutrons. From making balloons float to creating the computer chips in your smartphone, helium is in high demand on earth, but it is not an infinite resource. The need for this element continues to grow, but it is non-renewable noble gas, and the global supply is limited. Nichitiu started his research thinking of how describing neutron scattering signatures could help future space probes seek resources like helium from places beyond the constraints of our own planet. Nichitiu was also fascinated with helium’s behavior at very low temperatures.

    “If you take helium gas and you cool it down below 2.2 Kelvin, you get a special kind of liquid called a super fluid, which has zero viscosity” explained Nichitiu. “Since it has zero friction, it can just creep up the walls or through the tiniest crevices, which makes it really good for leak detection and for powering thermo-mechanical pumps in space. The discovery of the frictionless behavior of superfluid helium marked a cornerstone in modern physics with implications for the study of superconductivity and the universe’s phase transitions following the Big Bang.”

    Both scholars encourage students with a passion for STEM to ignore their doubts and apply. Applications for the 2024 search will be accepted from June of this year into November, leaving plenty of time to start planning out a research project to submit.

    “There’s no harm in applying,” said Nichitiu. “If you’re doing any sort of scientific research that you know you believe has some merit to the scientific community, you should definitely try. Even if it gets rejected, even if it’s not on par with the journals you would want to submit it to, it’s really important to get those basic scientific skills.”

    Brookhaven National Laboratory is supported by the Office of Science of the U.S. Department of Energy. The Office of Science is the single largest supporter of basic research in the physical sciences in the United States and is working to address some of the most pressing challenges of our time. For more information, please visit science.energy.gov.

    Follow @BrookhavenLab on Twitter or find us on Facebook.

    Brookhaven National Laboratory

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  • Strengthening ecology and conservation in the Global South

    Strengthening ecology and conservation in the Global South

    Newswise — The tropics hold most of the planet’s biodiversity. In order to preserve this fragile and valuable asset, many individuals and communities need to get involved and be well informed. However, tropical ecology and conservation sciences are still often affected by colonialistic and discriminatory practices, which can hamper nature conservation success. An international research team from leading universities in tropical research, including the University of Göttingen, has now proposed how researchers from the Global South, which consists of nations historically damaged by colonialism, could better promote solutions for a sustainable development. Their opinion paper was published in the journal Perspectives in Ecology and Conservation.

    The team of researchers from over 12 countries – across South America, Africa, Asia, Europe and North America – gathered their experiences working in international collaborations in the field of terrestrial and marine tropical ecology and conservation, and participating in committees promoting the diversification of scientific societies. They suggest ten actions for researchers living in the Global South to promote improvements in diversity, equity and inclusion. These include actions at institutional, national and international levels to guarantee that research teams in the Global South become more inclusive and diverse and are well prepared for equitable international research collaborations that have an impact on nature conservation practices.

    The authors believe that current teams in tropical research often do not fully consider the vast diversity of people and perspectives in tropical regions, which hinders the implementation of scientific practices. However, they recognize the high initial costs associated with establishing schemes for equitable participation: “These actions require hard work and self-reflection from all of us about our actions and attitudes, but we are confident that the benefits are considerable, both for the quality of the science that we do, and the protection of tropical ecosystems,” says lead author Carolina Ocampo-Ariza, Agroecology Group, University of Göttingen.

    Successful conservation actions rely on the participation of local stakeholders, including local governments and communities in rural areas. “We hope to encourage more leadership from those that live surrounded by tropical biodiversity,” says Professor Teja Tscharntke, University of Göttingen. This includes researchers in the Global South increasing outreach and dissemination in research projects, co-developing research goals with local stakeholders such as indigenous communities and local farmers, and taking a leading role in international research teams.

    “The ongoing international discussions about diversity, equity and inclusion will hopefully help us establish more sustainable and fair collaborations in research,” adds Isabelle Arimond, Functional Agrobiodiversity, University of Göttingen.

     

    Original publication: Ocampo-Ariza C et al, “Global South leadership towards inclusive tropical ecology and conservation”, Perspectives in Ecology and conservation: DOI: 10.1016/j.pecon.2023.01.002

    The abstract of the manuscript is available via PDF in 18 languages spoken in the Global South: https://www.sciencedirect.com/science/article/pii/S2530064423000020#sec0090

    University of Gottingen

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  • Five Faculty Selected for Newly Created “Rising Professorship”

    Five Faculty Selected for Newly Created “Rising Professorship”

    Newswise — Five from the Johns Hopkins School of Nursing (JHSON) have been selected as the inaugural holders of the newly established Term Professorship for Rising Faculty (Rising Professorship). The five faculty include Kamila Alexander, Teresa Brockie, Yvonne Commodore-Mensah, Laura Samuel, and Janiece Taylor.

    The Rising Professorship is a three-year period of funding for emerging and distinguished faculty to grow their research, increase their local, national, or global collaboration, strengthen their policy involvement, and advance their leadership within nursing and beyond.

    “We are delighted to announce this opportunity and to select these exceptional faculty,” says JHSON Dean Sarah Szanton, PhD, RN, FAAN. “This significant investment in faculty underscores our commitment to offering rising stars a place where they can both succeed in their careers and build the science, research, and networks needed to further nursing and improve health.”

    Kamila Alexander, PhD, MSN/MPH, RN, uses health equity and social justice lenses to examine the complex roles that intimate partner violence, HIV resilience, societal gender expectations, and economic opportunity play in the experience of intimate human relationships. Alexander is inaugural chair of the Nursing Initiative of the Mid-Atlantic Center for AIDS Research (CFAR) Consortium, lead faculty for the Violence Working Group at the Johns Hopkins Center for Injury Research and Policy, chair of the HIV/STI Committee of the Society for Adolescent Health and Medicine, and the associate director of the NIH-sponsored Interdisciplinary Research and Training in Trauma and Violence T32 Training Program at Johns Hopkins.

    Teresa Brockie, PhD, MSN, RN, FAAN, focuses on achieving health equity through community-based prevention and intervention of suicide, trauma, and adverse childhood experiences among vulnerable populations. Brockie is a member of the White Clay (A’aninin) Nation from Fort Belknap, Montana and leader of the Young Medicine Movement (YMM), which introduces Native youth to health science careers and provides mentorship by Indigenous researchers and clinicians to Fort Belknap scholars. Her intervention called Little Holy One aims to instill traditional Dakoda and Nakoda cultural values in children as a protective factor against adolescent suicide and substance use.

    Yvonne Commodore-Mensah, PhD, MHS, RN, FAHA, FPCNA, FAAN, seeks to reduce the burden of cardiovascular disease risk among Africans in the United States and in sub-Saharan Africa through community-engaged research and implementation science. She is a cardiovascular nurse epidemiologist and co-founder and president of the Ghanaian-Diaspora Nursing Alliance, a non-profit organization which advances nursing education in Ghana. Commodore-Mensah is principal investigator of the LINKED-BP and LINKED-HEARTS programs, two trials aimed to improve hypertension control and management of chronic conditions in community health centers.

    Laura Samuel, PhD, MSN, RN, FAAN, addresses socioeconomic disparities by advancing health equity for individuals and families with low incomes. Her current research examines the pathways that link low income and financial strain to physiologic aging. This includes investigating the health impact of policies and programs related to economic well-being for low-income households. Samuel’s research also looks at aspects of neighborhood and household environments that may influence health disparities. Her research interests stem from her clinical experience as a family nurse practitioner where she regularly witnessed the myriad of ways that a lack of financial resources can be detrimental to health.

    Janiece Taylor, PhD, MSN, RN, FAAN, identifies and addresses pain disparities with older women from underrepresented racial ethnic groups and helps individuals with disabilities increase social participation and independence. Taylor is principal investigator of a study that addresses unmet needs of caregivers aging with and into disabilities. She is co-associate director of JHSON’s RESILIENCE Center and principal faculty of its Center for Equity in Aging. Throughout her career, Taylor has received funding from the John A. Hartford Foundation, National Institute of Nursing Research, Mayday Foundation, the Robert Wood Johnson Foundation, Henry M. Jackson Foundation, and the Harold Amos Medical Faculty Program.

    “These faculty are already making tremendous impact. We can’t wait to see what they accomplish next.”

    ***

    Located in Baltimore, the Johns Hopkins School of Nursing is a globally-recognized leader in nursing education, research, and practice. In U.S. News & World Report rankings, the school is No. 1 nationally for its master’s and DNP programs. In addition, JHSON is ranked as the No. 3 nursing school in the world by QS World University and No. 1 for total NIH funding among schools of nursing for fiscal year 2020. The school is a four-time recipient of the INSIGHT Into Diversity Health Professions Higher Education Excellence in Diversity (HEED) Award and a three-time Best School for Men in Nursing award recipient. For more information, visit www.nursing.jhu.edu.

    Johns Hopkins School of Nursing

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