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Tag: medical diagnostics

  • Breast density changes over time could be linked to breast cancer risk, study finds | CNN

    Breast density changes over time could be linked to breast cancer risk, study finds | CNN

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    CNN
     — 

    Breast density is known to naturally decrease as a woman ages, and now a study suggests that the more time it takes for breast density to decline, the more likely it is that the woman could develop breast cancer.

    Researchers have long known that women with dense breasts have a higher risk of breast cancer. But according to the study, published last week in the journal JAMA Oncology, the rate of breast density changes over time also appears to be associated with the risk of cancer being diagnosed in that breast.

    “We know that invasive breast cancer is rarely diagnosed simultaneously in both breasts, thus it is not a surprise that we have observed a much slower decline in the breast that eventually developed breast cancer compared to the natural decline in density with age,” Shu Jiang, an associate professor of surgery at Washington University School of Medicine in St. Louis and first author of the new study, wrote in an email.

    Breast density refers to the amount of fibrous and glandular tissue in a person’s breasts compared with the amount of fatty tissue in the breasts – and breast density can be seen on a mammogram.

    “Because women have their mammograms taken annually or biennially, the change of breast density over time is naturally available,” Jiang said in the email. “We should make full use of this dynamic information to better inform risk stratification and guide more individualized screening and prevention approaches.”

    The researchers, from Washington University School of Medicine in St. Louis and Brigham and Women’s Hospital in Boston, analyzed health data over the course of 10 years among 947 women in the St. Louis region who completed routine mammograms. A mammogram is an X-ray picture of the breast that doctors use to look for early signs of breast cancer.

    The women in the study were recruited from November 2008 to April 2012, and they had gotten mammograms through October 2020. The average age of the participants was around 57.

    Among the women, there were 289 cases of breast cancer diagnosed, and the researchers found that breast density was higher at the start of the study for the women who later developed breast cancer compared with those who remained cancer-free.

    The researchers also found that there was a significant decrease in breast density among all the women over the course of 10 years, regardless of whether they later developed breast cancer, but the rate of density decreasing over time was significantly slower among breasts in which cancer was later diagnosed.

    “This study found that evaluating longitudinal changes in breast density from digital mammograms may offer an additional tool for assessing risk of breast cancer and subsequent risk reduction strategies,” the researchers wrote.

    Not only is breast density a known risk factor for breast cancer, dense breast tissue can make mammograms more difficult to read.

    “There are two issues here. First, breast density can make it more difficult to fully ‘see through’ the breast on a mammogram, like looking through a frosted glass. Thus, it can be harder to detect a breast cancer,” Dr. Hal Burstein, clinical investigator in the Breast Oncology Center at Dana-Farber Cancer Institute, who was not involved in the new study, said in an email. “Secondly, breast density is often thought to reflect the estrogen exposure or estrogen levels in women, and the greater the estrogen exposure, the greater the risk of developing breast cancer.”

    In March, the US Food and Drug Administration published updates to its mammography regulations, requiring mammography facilities to notify patients about the density of their breasts.

    “Breast density can have a masking effect on mammography, where it can be more difficult to find a breast cancer within an area of dense breast tissue,” Jiang wrote in her email.

    “Even when you take away the issue of finding it, breast density is an independent risk factor for developing breast cancer. Although there is lots of data that tell us dense breast tissue is a risk factor, the reason for this is not clear,” she said. “It may be that development of dense tissue and cancer are related to the same biological processes or hormonal influences.”

    The findings of the new study demonstrate that breast density serves as a risk factor for breast cancer – but women should be aware of their other risk factors too, said Dr. Maxine Jochelson, chief of the breast imaging service at Memorial Sloan Kettering Cancer Center in New York, who was not involved in the study.

    “It makes sense to some extent that the longer your breast stays dense, theoretically, the more likely it is to develop cancer. And so basically, it expands on the data that dense breasts are a risk,” Jochelson said, adding that women with dense breasts should ask for supplemental imaging when they get mammograms.

    But other factors that can raise the risk of breast cancer include having a family history of cancer, drinking too much alcohol, having a high-risk lesion biopsied from the breast or having a certain genetic mutation.

    For instance, women should know that “density may not affect their risk so much if they have the breast cancer BRCA 1 or 2 mutation because their risk is so high that it may not make it much higher,” Jochelson said.

    Some ways to reduce the risk of breast cancer include keeping a healthy weight, being physically active, drinking alcohol in moderation or not at all and, for some people, taking medications such as tamoxifen and breastfeeding your children, if possible.

    “Breast density is a modest risk factor. The ‘average’ woman in the US has a 1 in 8 lifetime chance of developing breast cancer. Women with dense breasts have a slightly greater risk, about 1 in 6, or 1 in 7. So the lifetime risk goes up from 12% to 15%. That still means that most women with dense breasts will not develop breast cancer,” Burstein said in his email.

    “Sometimes radiologists will recommend additional breast imaging to women with dense breast tissue on mammograms,” he added.

    The US Preventive Services Task Force – a group of independent medical experts whose recommendations help guide doctors’ decisions – recommends biennial screening for women starting at age 50. The task force says that a decision to start screening earlier “should be an individual one.” Many medical groups, including the American Cancer Society and Mayo Clinic, emphasize that women have the option to start screening with a mammogram every year starting at age 40.

    “It’s also very clear that breast density tends to be highest in younger women, premenopausal women, and for almost all women, it tends to go down with age. However, the risk of breast cancer goes up with age. So these two things are a little bit at odds with each other,” said Dr. Freya Schnabel, director of breast surgery at NYU Langone’s Perlmutter Cancer Center and professor of surgery at NYU Grossman School of Medicine in New York, who was not involved in the new study.

    “So if you’re a 40-year-old woman and your breasts are dense, you could think about that as just being really kind of age-appropriate,” she said. “The take-home message that’s very, very practical and pragmatic right now is that if you have dense breasts, whatever your age is, even if you’re postmenopausal – maybe even specifically, if you are postmenopausal – and your breasts are not getting less dense the way the average woman’s does, that it really is a reason to seek out adjunctive imaging in addition to just mammography, to use additional diagnostic tools, like ultrasound or maybe even MRI, if there are other risk factors.”

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  • 5 things to know for April 21: Starship, Biden, Gun violence, North Dakota, Theranos | CNN

    5 things to know for April 21: Starship, Biden, Gun violence, North Dakota, Theranos | CNN

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    CNN
     — 

    Artificial intelligence tools like ChatGPT have shown they can be remarkably adept at everything from generating student essays to writing wedding vows and even composing sermons for pastors and rabbis. Now, one city is turning to the AI chatbot for something else: helping to run the government.

    Here’s what else you need to know to Get Up to Speed and On with Your Day.

    (You can get “CNN’s 5 Things” delivered to your inbox daily. Sign up here.)

    SpaceX’s Starship, the most powerful rocket ever built, exploded midair shortly after it launched on Thursday from Texas. No injuries or property damages were reported following the explosion of the unmanned rocket, the FAA said. CEO Elon Musk congratulated the company and said the team “learned a lot” from the “rapid unscheduled disassembly.” Preparations are now underway for the company’s next test launch, which Musk said will happen in a few months. SpaceX is known to embrace fiery mishaps during the rocket development process. The company maintains that such accidents are the quickest and most efficient way of gathering data, an approach that sets the company apart from its close partner NASA, which prefers slow, methodical testing over dramatic flare-ups.

    Plans are underway for President Joe Biden to formally announce his bid for a second term as soon as next week, according to several sources familiar with the matter. A campaign-style video is set to be released to definitively answer the question of whether he will run again and ignite an aggressive fundraising effort to help Democrats hold the White House. Advisers inside and outside the White House caution that timing could still change, pending unforeseen events, but a decision has been reached that it is “no longer helpful or necessary to not just say the obvious: He’s running,” a senior Democratic official told CNN. Biden’s campaign headquarters will be based in Wilmington, Delaware, aides said, as a nod to the pride in his hometown and the place where he spends most of his weekends.

    Biden expected to announce reelection bid next week

    he shooter who killed five co-workers at a Louisville, Kentucky, bank this month left notes that revealed part of his goal was to show how easy it was in America for someone dealing with a serious mental illness to buy an assault-style weapon. The gunman purchased the AR-15-style rifle seven days before the April 10 shooting after quickly passing a records check. Separately, communities across the US are grieving several recent shootings in which young people were shot after making a common blunder. Among the cases, a 6-year-old girl was shot after an angry neighbor opened fire over a basketball rolling into his yard. Other young victims include two teenage cheerleaders in Texas who mistakenly approached someone else’s vehicle in a grocery store parking lot, a 16-year-old boy who rang the wrong doorbell in Kansas City and a 20-year-old woman who turned into the wrong New York driveway.

    Louisville Body Cam

    Video shows officers walking head-on into gunfire to stop Louisville shooter

    North Dakota’s Republican Gov. Doug Burgum signed a bill this week banning gender-affirming care for most minors. Burgum, in a statement to CNN, said the bill “is aimed at protecting children from the life-altering ramifications of gender reassignment surgeries.” It also bars providers from prescribing minors puberty-blocking medication and hormone therapies for the purpose of gender transition. Health care professionals who violate the new legislation could face a class B felony charge, which is punishable by up to 10 years in prison or a fine of $20,000, according to North Dakota law. This comes as a growing number of states are restricting access to health care services for transgender youth. Indiana and Idaho enacted their own bans earlier this month, and several other states have signed into law restrictions on gender-affirming care for minors since the start of the year.

    The former chief operating officer of the failed startup Theranos, Ramesh “Sunny” Balwani, has reported to prison, according to his attorney. Once valued at $9 billion, Theranos attracted top investors and retail partners with claims that it had developed technology to test for a wide range of conditions using just a few drops of blood. The company began to unravel after a Wall Street Journal investigation in 2015 revealed Theranos had only ever performed roughly a dozen of the hundreds of tests it offered using its proprietary technology, and with questionable accuracy. Balwani’s arrival into custody this week marks an end to a yearslong saga which saw him become one of the rare tech executives convicted for fraud. The founder of the company, Elizabeth Holmes, was also convicted on multiple counts of defrauding investors and has been ordered to turn herself in next week.

    Ramadan ends today with the arrival of Eid al-Fitr

    For many Muslims, today brings the end of Ramadan, the Islamic holy month of fasting. The conclusion of the 30-day fast is celebrated with delicious feasts around the world.

    What it’s like to be a theme park designer

    With this cool job, some of the most out-of-the-box ideas are greatly appreciated. Oh, and did we mention plenty of free perks are involved?

    Man loses it on plane over crying baby

    A passenger threw a total fit over a crying baby on his flight. Watch the meltdown here.

    Gwyneth Paltrow leaves door open for further involvement in the Marvel Cinematic Universe

    Never say never! The actress who starred in “Iron Man” and “Avengers” said she would consider a return if asked. 

    Ikea announces $2 billion expansion in the US

    The retailer is making its biggest-ever investment in a single country with several new stores set to open in the US over the next three years.

    Which small intruder crawled through a fence at the White House this week, prompting a swift response from the US Secret Service?

    A. Snake

    B. Dog

    C. Cat

    D. Toddler

    Take CNN’s weekly news quiz to see if you’re correct!

    $500 million

    That’s how much President Biden on Thursday pledged to invest in curbing deforestation in the Amazon rainforest. The sum would make the US one of the world’s largest donors to the Amazon Fund, an international conservation program that aims to preserve the environment in the South American region.

    “Our investigators have their eyes open to all avenues.”

    — Stephen Duivesteyn, a police spokesman in Canada, announcing that a cargo container carrying more than $15 million in gold and other valuables disappeared from Toronto’s Pearson International Airport this week. Police are still trying to find out who is behind the high-value heist.

    Check your local forecast here>>>

    The fastest window cleaner in the world

    This man holds several Guinness World Records for his turbo squeegee techniques. Watch this quick video to see him in action. (Click here to view)

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  • Watch: Video shows moment Indian politician was shot on live TV | CNN

    Watch: Video shows moment Indian politician was shot on live TV | CNN

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    Atiq Ahmed, a former lawmaker in India’s parliament, convicted of kidnapping, was shot dead along with his brother while police were escorting them for a medical check-up in a slaying caught on live television on Saturday. CNN’s Vedika Sud reports.

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  • Federal judge says insurers no longer have to provide some preventive care services, including cancer and heart screenings, at no cost | CNN Politics

    Federal judge says insurers no longer have to provide some preventive care services, including cancer and heart screenings, at no cost | CNN Politics

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    CNN
     — 

    A federal judge in Texas said Thursday that some Affordable Care Act mandates cannot be enforced nationwide, including those that require insurers to cover a wide array of preventive care services at no cost to the patient, including some cancer, heart and STD screenings, and tobacco programs.

    In the new ruling, US District Judge Reed O’Connor struck down the recommendations that have been issued by the US Preventive Services Task Force, which is tasked with determining some of the preventive care treatments that Obamacare requires to be covered.

    The decision applies to task force recommendations issued on or after March 23, 2010 – the day the Affordable Care Act was signed into law. While the group had recommended various preventive services prior to that date, nearly all have since been updated or expanded.

    O’Connor’s ruling comes after the judge had already said that the task force’s recommendations violated the Constitution’s Appointments Clause. The judge also deemed unlawful the ACA requirement that insurers and employers offer plans that cover HIV-prevention measures such as PrEP for free.

    Other preventive care mandates under the ACA remain in effect.

    The full extent of the ruling’s impact and when its effects could be felt are unclear.

    It is likely the case will be appealed, and the Justice Department has the option to ask that O’Connor’s ruling be put on pause while the appeal is litigated.

    The Justice Department did not immediately respond to a CNN request for comment, nor did the US Department of Health and Human Services.

    White House spokesperson Karine Jean-Pierre called the case “yet another attack on the Affordable Care Act” and said that DOJ and HHS were reviewing Thursday’s ruling.

    The decision, in a case brought by employers and individuals in Texas, represents the latest legal affront to the landmark 2010 health care law. It is unclear what immediate practical effect O’Connor’s new ruling will have for those with job-based and Affordable Care Act policies because insurance companies will likely continue no-cost coverage for the remainder of the contracts even though the Obamacare requirements in question have been blocked. Contracts often last one calendar year.

    O’Connor’s Thursday ruling is expected to kick off a new phase of the legal battle over Obamacare’s preventive care measures. The judge rejected other claims that the ACA’s foes brought against the law – including challenges to the entities that determine no-cost coverage mandates for vaccines, an assortment of women’s health preventive care treatments, and services for infants and children. It’s possible that the plaintiffs appeal those aspects of O’Connor’s handling of the case, which could put at risk coverage requirements for additional preventive services at no cost.

    A lawyer for the challengers did not respond to CNN’s inquiry about Thursday’s decision.

    O’Connor is a George W. Bush-appointee who sits in the Northern District of Texas and who has issued anti-Obamacare rulings in major challenges to the law in the past. An appeal of the current case would head to the 5th US Circuit Court of Appeals, perhaps the most conservative federal appeals court in the country.

    While the case does not pose the existential threat to the Affordable Care Act that previous legal challenges did, legal experts say that O’Connor’s ruling nonetheless puts in jeopardy the access some Americans will have to a whole host of preventive treatments.

    “We lose a huge chunk of preventive services because health plans can now impose costs,” said Andrew Twinamatsiko, associate director of the O’Neill Institute for National and Global Health Law at Georgetown University. “People who are sensitive to cost will go without, mostly poor people and marginalized communities.”

    Thursday’s ruling, if left standing, could have significant consequences for Americans nationwide by limiting access to key preventive services aimed at early detection of diseases, including lung and colorectal cancer, depression and hypertension.

    Some of the US Preventive Services Task Force’s recommendations – including lung and skin cancer screenings, the use of statins to prevent cardiovascular disease and the offer of PrEP for those at high risk of HIV – were issued after the ACA’s enactment.

    Certain older recommendations have been updated with new provisions, such as screening adults ages 45 to 49 for colorectal cancer.

    “It would effectively lock in place coverage of evidence-based prevention with no cost sharing from 13 years ago,” said Larry Levitt, executive vice president for health policy at the Kaiser Family Foundation.

    Some of the cost-sharing for these preventive services can be substantial. PrEP, for instance, can cost up to $20,000 a year, plus lab and provider charges, according to Kaiser.

    In an earlier ruling, the judge upheld certain free preventive services for children, such as autism and vision screenings and well-baby visits, and for women, such as mammograms, well-woman visits and breastfeeding support programs.

    O’Connor also upheld the mandate that provides immunizations at no charge for the flu, hepatitis, measles, shingles and chickenpox.

    These services are recommended by the Health Resources and Services Administration and the Advisory Committee on Immunization Practices.

    Insurers will have to continue to cover preventive and wellness services since they are one of the Affordable Care Act’s required essential health benefits. But under O’Connor’s ruling, they could require patients to pick up part of the tab.

    Insurers’ trade associations stressed there would be no immediate disruption to coverage.

    “It is vitally important for patients to know that their care and coverage will not change because of today’s court decision,” said David Merritt, senior vice president of policy and advocacy for the Blue Cross Blue Shield Association. “Blue Cross and Blue Shield companies strongly encourage their members to continue to access these services to promote their continued well-being. We will continue to monitor further developments in the courts.”

    More than 150 million people with private insurance can receive preventive services without cost-sharing under the Affordable Care Act, according to a 2022 report published by HHS.

    Overall, about 60% of the 173 million people enrolled in private health coverage used at least one of the ACA’s no-cost preventive services in 2018 prior to the Covid-19 pandemic, according to a recent Kaiser analysis. These include some services that will continue to be available at no charge under the judge’s ruling.

    The most commonly received preventive care includes vaccinations, not including Covid-19 vaccines, well-woman and well-child visits, and screenings for heart disease, cervical cancer, diabetes and breast cancer, according to Kaiser. The most commonly used preventive services will continue to be covered at no cost.

    Studies have shown the Obamacare mandate prompted an uptake in preventive services and narrowed care disparities in communities of color.

    “There’s plenty of evidence that people responded to this incentive and started using preventive care more often,” said Paul Shafer, assistant professor of health policy at Boston University.

    This story has been updated with additional details.

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  • Former Theranos COO sentenced to nearly 13 years | CNN Business

    Former Theranos COO sentenced to nearly 13 years | CNN Business

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    CNN Business
     — 

    Ramesh “Sunny” Balwani, the former chief operating officer of failed blood testing startup Theranos, was sentenced Wednesday to nearly 13 years in prison for fraud. It marks an end to the stunning downfall of a high-flying Silicon Valley company that resulted in the rare convictions of two tech executives.

    “There is an unfortunate saying in Silicon Valley: ‘Fake it ‘til you make it.’ Elizabeth Holmes and Sunny Balwani stretched this idea to a place much farther than the law allows and in so doing put vast amounts of investor dollars at risk,” said Stephanie Hinds, US Attorney for the Northern District of California, in a statement. “Significantly, today the court also made clear that Sunny Balwani’s decision to deceive doctors and patients also put the health of patients at risk. Ms. Holmes and Mr. Balwani now will be justly punished for their illegal conduct.”

    Hinds added, “Let this story be a cautionary tale for entrepreneurs in this district: Those who use lies to cover up the shortfalls of their promised accomplishments risk substantial jail time.”

    The sentencing comes weeks after Elizabeth Holmes, the founder of Theranos and Balwani’s ex-girlfriend, was sentenced to more than 11 years in prison.

    Theranos raised $945 million from an A-list cohort of investors with its promise to test for a wide range of conditions using just a few drops of blood. At its peak, the company was valued at $9 billion.

    The company began to unravel after a Wall Street Journal investigation in 2015 reported that Theranos had only ever performed roughly a dozen of the hundreds of tests it offered using its proprietary technology, and with questionable accuracy. It also came to light that Theranos was relying on third-party manufactured devices from traditional blood testing companies rather than its own technology. Theranos ultimately dissolved in September 2018.

    Holmes and Balwani were first indicted together four years ago on the same 12 criminal charges pertaining to defrauding investors and patients about Theranos’ capabilities and business dealings in order to get money. Their trials were severed after Holmes indicated she intended to accuse Balwani of sexually, emotionally and psychologically abusing her throughout their decade-long relationship, which coincided with her time running the company. (Balwani’s attorneys have denied her claims.)

    In July, Balwani was found guilty on all 12 charges he faced, which included ten counts of federal wire fraud and two counts of conspiracy to commit wire fraud. Holmes was found guilty in January on four charges relating to defrauding investors, and found not guilty on three additional charges concerning defrauding patients and one charge of conspiracy to defraud patients.

    Like Holmes, Balwani faced up to 20 years in prison as well as a fine of $250,000 plus restitution for each count.

    In a recent court filing, prosecutors noted that Balwani was convicted not only of defrauding investors but also defrauding patients. They recommended a 15-year prison sentence for him, as well as an order for Balwani to pay $804 million in restitution. In a separate filing, attorneys for Balwani requested a sentence of probation, noting he had no criminal history.

    Before joining Theranos, Balwani had a career as a software executive. Balwani, nearly 20 years older than Holmes, first met her in 2002 before she dropped out of Stanford. He served as an informal adviser to Holmes in Theranos’ earliest days and the two became romantically involved. Balwani guaranteed a “multimillion-dollar loan” to the startup in 2009, court filings show, and took on a formal role as president and chief operating officer. Holmes and Balwani largely kept their romantic relationship hidden while working together.

    During her trial, Holmes claimed Balwani tried to control nearly every aspect of her life — including disciplining her eating, her voice and image, and isolating her from others. She testified that while he didn’t control her interactions with investors, business partners and others, “he impacted everything about who I was, and I don’t fully understand that.”

    Holmes is expected to appeal her conviction but was ordered to turn herself into custody on April 27, 2023.

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  • The rise and fall of Elizabeth Holmes: A timeline | CNN Business

    The rise and fall of Elizabeth Holmes: A timeline | CNN Business

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    CNN
     — 

    More than three years after Elizabeth Holmes was first indicted and nearly four months after her trial kicked off, the founder and former CEO of failed blood testing startup Theranos was found guilty on four out of 11 federal fraud and conspiracy charges.

    The verdict comes after a stunning downfall that saw Holmes, once hailed as the next Steve Jobs, go from being a tech industry icon to being a rare Silicon Valley entrepreneur on trial for fraud.

    A Stanford University dropout, Holmes – inspired by her own fear of needles – started the company at the age of 19, with a mission of creating a cheaper, more efficient alternative to a traditional blood test. Theranos promised patients the ability to test for conditions like cancer and diabetes with just a few drops of blood. She attracted hundreds of millions of dollars in funding, a board of well-known political figures, and key retail partners.

    But a Wall Street Journal investigation poked holes into Theranos’ testing and technology, and the dominoes fell from there. Holmes and her former business partner, Ramesh “Sunny” Balwani, were charged in 2018 by the US government with multiple counts of wire fraud and conspiracy to commit wire fraud. (Both pleaded not guilty.)

    Here are the highlights of the rise and fall of Elizabeth Holmes and Theranos.

    Holmes, a Stanford University sophomore studying chemical engineering, drops out of school to pursue her startup, Theranos, which she founded in 2003 at age 19. The name is a combination of the words “therapy” and “diagnosis.”

    Balwani joins as chief operating officer and president of the startup. Balwani, nearly 20 years her senior, met Holmes in 2002 on a trip to Beijing through Stanford University. The two are later revealed to be romantically involved.

    A decade after first starting the company, Holmes takes the lid off Theranos and courts media attention the same month that Theranos and Walgreens announce they’ve struck up a long-term partnership. The first Theranos Wellness Center location opens in a Walgreens in Palo Alto where consumers can access Theranos’ blood test.

    The original plan had been to make Theranos’ testing available at Walgreens locations nationwide.

    Holmes is named to the magazine’s American billionaire list with the outlet reporting she owns a 50% stake in the startup, pinning her personal wealth at $4.5 billion.

    Theranos has raised more than $400 million, according to a profile of the company and Holmes by The New Yorker. It counts Oracle’s Larry Ellison among its investors.

    The FDA clears Theranos to use of its proprietary tiny blood-collection vials to finger stick blood test for herpes simplex 1 virus – its first and only approval for a diagnostic test.

    The Wall Street Journal reports Theranos is using its proprietary technique on only a small number of the 240 tests it performs, and that the vast majority of its tests are done with traditional vials of blood drawn from the arm, not the “few drops” taken by a finger prick. In response, Theranos defends its testing practices, calling the Journal’s reporting “factually and scientifically erroneous.”

    A day later, Theranos halts the use of its blood-collection vials for all but the herpes test due to pressures from the FDA. (Later that month, the FDA released two heavily redacted reports citing 14 concerns, including calling the company’s proprietary vial an “uncleared medical device.”)

    One week after the Journal report, Holmes is interviewed on-stage at the outlet’s conference in Laguna Beach. “We know what we’re doing and we’re very proud of it,” she says.

    Holmes speaking at a Wall Street Journal technology conference in Laguna Beach, California on October 21, 2015.

    Amid the criticism, Theranos reportedly shakes up its board of directors, eliminating Henry Kissinger and George Shultz as directors while moving them to a new board of counselors; the company also forms a separate medical board.

    Safeway, which invested $350 million into building out clinics in hundreds of its supermarkets to eventually offer Theranos blood tests, reportedly looks to dissolve its relationship with the company before it ever offered its services.

    Centers for Medicare and Medicaid Services (CMS) sends Theranos a letter saying its California lab has failed to comply with federal standards and that patients are in “immediate jeopardy.” It gives the company 10 days to address the issues.

    In response, Walgreens says it will not send any lab tests to Theranos’ California lab for analysis and suspends Theranos services at its Palo Alto Walgreens location.

    CMS threatens to ban Holmes and Balwani from the laboratory business for two years after the company allegedly failed to fix problems at its California lab. Theranos says that’s a “worst case scenario.

    Balwani departs. The company also adds three new board members as part of the restructuring: Fabrizio Bonanni, a former executive vice president of biotech firm Amgen, former CDC director William Foege, and former Wells Fargo CEO Richard Kovacevich.

    Theranos voids two years of blood test results from its proprietary testing devices, correcting tens of thousands of blood-test reports, the Journal reports.

    Forbes revises its estimate of Holmes’ net worth from $4.5 billion to $0. The magazine also lowers its valuation for the company from $9 billion to $800 million.

    Walgreens, once Theranos’ largest retail partner, ends its partnership with the company and says it will close all 40 Theranos Wellness Centers.

    CMS revokes Theranos’ license to operate its California lab and bans Holmes from running a blood-testing lab for two years.

    Holmes tries to move past recent setbacks by unveiling a mini testing laboratory, called miniLab, at a conference for the American Association for Clinical Chemistry. In selling the device, versus operating its own clinics, Theranos seeks to effectively side-step CMS sanctions, which don’t prohibit research and development.

    Theranos investor Partner Fund Management sues the company for $96.1 million, the amount it sunk into the company in February 2014, plus damages. It accuses the company of securities fraud. Theranos and Partner Fund Management settled in May, 2017, for an undisclosed amount.

    The company also lays off 340 employees as it closes clinical labs and wellness centers as it attempts to pivot and focus on the miniLab.

    Walgreens sues the blood testing startup for breach of contract. Walgreens sought to recover the $140 million it poured into the company. The lawsuit was settled August, 2017.

    Theranos downsizes its workforce yet again following the increased scrutiny into its operations, laying off approximately 155 employees or about 41% of staffers.

    The Wall Street Journal reports that Theranos failed a second regulatory lab inspection in September, and that the company was closing its last blood testing location as a result.

    Theranos settles with the CMS, agreeing to pay $30,000 and to not to own or operate any clinical labs for two years.

    Theranos also settles with the Arizona Attorney General Mark Brnovich over allegations that its advertisements misrepresented the method, accuracy, and reliability of its blood testing and that the company was out of compliance with federal regulations governing clinical lab testing. Theranos agrees to pay $4.65 million back to its Arizona customers as part of a settlement deal.

    The SEC charges Holmes and Balwani with a “massive fraud” involving more than $700 million from investors through an “elaborate, years-long fraud in which they exaggerated or made false statements about the company’s technology, business, and financial performance.”

    The SEC alleges Holmes and Balwani knew that Theranos’ proprietary analyzer could perform only 12 of the 200 tests it published on its patient testing menu.

    Theranos and Holmes agree to resolve the claims against them, and Holmes gives up control of the company and much of her stake in it. Balwani, however, is fighting the charges, with his attorney saying he “accurately represented Theranos to investors to the best of his ability.”

    Reporter John Carreyrou, who first broke open the story of Theranos for the Wall Street Journal, publishes “Bad Blood,” a definitive look at what happened inside the disgraced company. Director Adam McKay (who directed “The Big Short”) secures the rights to make the film, starring Jennifer Lawrence as Holmes, by the same name.

    Holmes and Balwani are indicted on federal wire fraud charges over allegedly engaging in a multi-million dollar scheme to defraud investors, as well as a scheme to defraud doctors and patients. Both have pleaded not guilty.

    Minutes before the charges were made public, Theranos announced that Holmes has stepped down as CEO. The company’s general counsel, David Taylor, takes over as CEO. Holmes remains chair of the company’s board.

    Former Theranos COO Ramesh

    Taylor emails shareholders that Theranos will dissolve, according to a report from The Wall Street Journal. Taylor said more than 80 potential buyers were not interested in a sale. “We are now out of time,” Taylor wrote.

    Alex Gibney, the prolific documentary filmmaker behind “Dirty Money,” “Enron: The Smartest Guys in the Room,” and “The Armstrong Lie,” debuts “The Inventor” on HBO, following the rise and fall of Theranos.

    A new court document reveals Holmes may seek a “mental disease” defense in her criminal fraud trial. Later, in August 2021, unsealed court documents reveal Holmes is likely to claim she was the victim of a decade-long abusive relationship with Balwani. The allegations led to the severing of their trials. His trial is slated to begin in 2022.

    Initially set to begin in July 2020, Holmes’ criminal trial is further delayed til July 2021 due to the coronavirus pandemic.

    News surfaces that Holmes’ is expecting her first child, once more further delaying her criminal trial. Holmes’ counsel advised the US government that Holmes is due in July 2021, a court document revealed. She gave birth in July.

    Holmes collects her belongings after going through security at the Robert F. Peckham Federal Building with her defense team on August 31, 2021 in San Jose, California.

    More than 80 potential jurors are brought into a San Jose courtroom for questioning over the course of two days to determine if they are fit to serve as impartial, fair jurors for the criminal trial of Holmes. A jury of seven men and five women is selected, with five alternatives.

    After three months of testimony from 32 witnesses, the criminal fraud case of Theranos founder Elizabeth Holmes makes its way to the jury of eight men and four women who will decide her fate. The jury would go on to deliberate for more than 50 hours before returning a verdict.

    Holmes is found guilty of one count of conspiracy to defraud investors as well as three wire fraud counts tied to specific investors. She is found not guilty on three additional charges concerning defrauding patients and one charge of conspiracy to defraud patients. The jury returns no verdict on three of the charges concerning defrauding investors. Holmes faces up to 20 years in prison as well as a fine of $250,000 plus restitution for each count.

    “The Dropout,” a scripted miniseries about Theranos produced by ABC, debuts on Hulu. Amanda Seyfried stars as Holmes and Naveen Andrews plays Balwani. Their romantic and professional relationship features prominently in the show.

    Following delays due to Holmes’ prolonged trial then a surge of Covid-19, jury selection for Balwani’s trial gets underway. On March 22, opening arguments are held and the government’s first witness, a former Theranos employee turned whistleblower, is called to the stand.

    After four full days of deliberations, a jury finds Balwani guilty of ten counts of federal wire fraud and two counts of conspiracy to commit wire fraud. Like Holmes, Balwani faces up to 20 years in prison as well as a fine of $250,000 plus restitution for each count of wire fraud and each conspiracy count.

    Holmes asks for a new trial after claiming that a key witness visited her house unannounced and allegedly said he “feels guilty” about his testimony.

    In a court filing with the United States District Court for the Northern District of California, Holmes’ attorneys said Adam Rosendorff, a former Theranos lab director who was one of the government’s main witnesses, arrived at her home on August 8 asking to speak with her. According to the filing, Rosendorff did not interact with Holmes but did speak to her partner Billy Evans, who recounted the exchange in an email to Holmes’ lawyers shortly after.

    “His shirt was untucked, his hair was messy, his voice slightly trembled,” Evans wrote about Rosendorff. According to Evans’ email, Rosendorff “said when he was called as a witness he tried to answer the questions honestly but that the prosecutors tried to make everybody look bad.”

    The former Theranos lab director also “said he felt like he had done something wrong,” Evans wrote.

    Rosendorff takes the stand again to address concerns from Holmes’ defense team and their claims he had shown up at her home after the trial concluded asking to speak with her and expressed regrets about his testimony.

    At the hearing, Rosendorff reaffirmed the truthfulness of his testimony at Holmes’ trial and said that the government did not influence what he said.

    A federal judge denies Elizabeth Holmes’ request for a new trial, according to court filings, paving the way for the founder of failed blood testing startup Theranos to be sentenced later in the month.

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  • Elizabeth Holmes scheduled to be sentenced on Friday | CNN Business

    Elizabeth Holmes scheduled to be sentenced on Friday | CNN Business

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    CNN
     — 

    Elizabeth Holmes, the founder of failed blood testing startup Theranos who was convicted of fraud earlier this year, is scheduled to be sentenced on Friday morning by a judge in court in San Jose, California.

    Holmes, who was found guilty in January on four charges of defrauding investors, faces up to 20 years in prison as well as a fine of $250,000 plus restitution for each count.

    Lawyers for the government asked for a 15-year prison term, as well as probation and restitution, while Holmes’ probation officer pushed for a nine-year term. Holmes’ defense team asked Judge Edward Davila, who is presiding over her case, to sentence her to up to 18 months of incarceration followed by probation and community service.

    More than 100 people wrote letters in support of Holmes to Davila, asking for leniency in her sentencing. The list includes Holmes’ partner, Billy Evans, many members of Holmes’ and Evans’ families, early Theranos investor Tim Draper, and Sen. Cory Booker. Booker described meeting her at a dinner years before she was charged and bonding over the fact that they were both vegans with nothing to eat but a bag of almonds, which they shared.

    “I still believe that she holds onto the hope that she can make contributions to the lives of others, and that she can, despite mistakes, make the world a better place,” Booker wrote, noting that he continues to consider her a friend.

    Friday’s sentencing hearing caps off Holmes’ stunning downfall. Once hailed as a tech industry icon for her company’s promises to test for a range of conditions with just a few drops of blood, she is now the rare tech founder to be convicted and face prison time for her company’s missteps.

    Holmes, now 38, started Theranos in 2003 at the age of 19 and soon thereafter dropped out of Stanford University to pursue the company full-time. After a decade under the radar, Holmes began courting the press with claims that Theranos had invented technology that could accurately and reliably test for a range of conditions using just a few drops of blood taken from a finger prick.

    Theranos raised $945 million from an impressive list of investors, including media mogul Rupert Murdoch, Oracle founder Larry Ellison, Walmart’s Walton family and the billionaire family of former Secretary of Education Betsy DeVos. At its peak, Theranos was valued at $9 billion, making Holmes a billionaire on paper. She was lauded on magazine covers, frequently wearing a signature black turtleneck that invited comparisons to late Apple CEO Steve Jobs. (She has not worn that look in the courtroom.)

    The company began to unravel after a Wall Street Journal investigation in 2015 found the company had only ever performed roughly a dozen of the hundreds of tests it offered using its proprietary blood testing device, and with questionable accuracy. Instead, Theranos was relying on third-party manufactured devices from traditional blood testing companies.

    In 2016, Theranos voided two years of blood test results. In 2018, Holmes and Theranos settled “massive fraud” charges with the Securities and Exchange Commission, but did not admit to or deny any of the allegations as part of the deal. Theranos dissolved soon after.

    In her trial, Holmes alleged she was in the midst of a decade-long abusive relationship with her then-boyfriend and Theranos COO Ramesh “Sunny” Balwani while running the company. Balwani, she alleged, tried to control nearly every aspect of her life, including disciplining her eating, her voice and her image, and isolating her from others. (Balwani’s attorneys denied her claims.)

    In July, Balwani was found guilty on all 12 charges in a separate trial and faces the same potential maximum prison time as her. Balwani is scheduled to be sentenced on December 7.

    “The effects of Holmes and Balwani’s fraudulent conduct were far-reaching and severe,” federal prosecutors wrote in a November court filing regarding Holmes’ sentencing. “Dozens of investors lost over $700 million and numerous patients received unreliable or wholly inaccurate medical information from Theranos’ flawed tests, placing those patients’ health at serious risk.”

    Holmes’ sentencing, however, could be complicated by developments in her life after stepping down from Theranos. Holmes and her partner, Evans, who met in 2017, have a young son. Holmes is also pregnant, as confirmed by recent court filings and her most recent court appearance in mid October.

    Mark MacDougall, a white-collar defense lawyer and former federal prosecutor, told CNN Business that the fact that Holmes has a young child could impact how she is sentenced.

    “I don’t know how it can’t, just because judges are human,” he said.

    MacDougall also said he doesn’t see what a long prison sentence accomplishes. “Elizabeth Holmes is never going to run a big company again,” he said. “She’s never going to be in a position to have something like this happen again.”

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  • Elizabeth Holmes’ request for a new trial is denied | CNN Business

    Elizabeth Holmes’ request for a new trial is denied | CNN Business

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    CNN
     — 

    A federal judge has denied Elizabeth Holmes’ request for a new trial, according to court filings on Monday, paving the way for the founder of failed blood testing startup Theranos to be sentenced later this month.

    The decision comes weeks after an October 17 hearing held in San Jose, during which Judge Edward Davila had Adam Rosendorff, one of the government’s key witnesses, take the stand again. The hearing was to address concerns from Holmes’ defense team, which claimed Rosendorff had shown up at her home after the trial concluded asking to speak with her and expressed regrets about his testimony.

    At that hearing in the United States District Court for the Northern District of California, Rosendorff, a former Theranos lab director, reaffirmed the truthfulness of his testimony at Holmes’ trial and said that the government did not influence what he said.

    In his decision on Monday, Davila denied all three of Holmes’ motions requesting a new trial. A sentencing hearing, previously scheduled for last month, is now set for November 18.

    Holmes, once hailed as a tech industry icon for her company’s promises to test for a range of conditions with just a few drops of blood, was found guilty in January on four charges of defrauding investors. Ramesh “Sunny” Balwani, her ex-boyfriend and former COO at Theranos, was convicted in a separate trial in July. Both face up to 20 years in prison as well as a fine of $250,000 plus restitution for each count.

    In September, Holmes’ defense team filed a motion asking for a new trial, after claiming that Rosendorff arrived at Holmes’ home on August 8. According to that court filing, Rosendorff did not interact with Holmes but did speak to her partner Billy Evans, who recounted the exchange in an email to Holmes’ lawyers shortly after.

    In Evans’ email, he wrote that Rosendorff “said when he was called as a witness he tried to answer the questions honestly but that the prosecutors tried to make everybody look bad.” The former Theranos lab director also “said he felt like he had done something wrong,” Evans wrote.

    Davila wrote in his order Monday that the court “finds that the statements Dr. Rosendorff made to Mr. Evans do not stand for any of the proposed meanings that Defendant would want and, even if they did, they would not be material to the issues” at trial.

    “Accordingly, a new trial is not warranted based on the ‘newly discovered’ evidence of Dr. Rosendorff’s statements to Mr. Evans,” Davila wrote.

    In a sworn declaration filed with the court on September 21, Rosendorff wrote that he stands by his testimony in the trials of Holmes and Balwani “in every respect.”

    During the hearing last month, Holmes and Evans were present as Rosendorff was asked by a defense lawyer about his decision to visit Holmes’ home. He responded that in the weeks and months following Holmes’ conviction he “started to feel increasingly distressed and uncomfortable at the prospect that a young child, an infant child, would spend their formative years without a mother in their life.” (Holmes has one child with Evans.)

    Rosendorff said that when he visited Holmes’ residence in August, he rang the doorbell and spoke briefly to Evans, who asked him to leave. He went to his car and started to drive away, he testified, but Evans motioned for him to roll down his window; he did, and they had a conversation, Rosendorff said, in which he “expressed sympathy for the rank and file employees at Theranos.”

    When asked by the defense lawyer whether he had said the prosecution was trying to make everyone look bad, Rosendorff said that the prosecution was trying to paint “an angry picture of Elizabeth Holmes. To the extent other people looked bad it was because of their association with Elizabeth.”

    He said he did not recall telling Evans that he felt he had done something wrong, as Evans had written in his email to Holmes’ lawyers after their interaction.

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  • Carolina Panthers trade Christian McCaffrey to the San Francisco 49ers, pending physical exam | CNN

    Carolina Panthers trade Christian McCaffrey to the San Francisco 49ers, pending physical exam | CNN

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    CNN
     — 

    The Carolina Panthers have confirmed running-back Christian McCaffrey will be traded to the San Francisco 49ers, pending a physical exam, in exchange for a host of draft picks.

    According to NFL.com, the deal will see the Panthers receive a second, third and fourth-round pick in the 2023 draft, as well as a fifth-round pick in 2024.

    It comes at a time when the Panthers are looking to rebuild the roster and center it around a host of emerging young talent.

    McCaffrey has enjoyed an impressive and lengthy stay at the Panthers, joining as a first-round pick in 2017.

    His best year came in 2019, when he led the league in yards from scrimmage with 2,392 and he ran a career-best of 1,387 yards.

    Injuries in 2020 and 2021 have limited his playing time since then but the 26-year-old has remained relatively healthy this year, ranking 12th in the NFL in carries (85), 13th in rushing yards (393), 31st in targets (43) and 19th in receptions (33).

    The franchise fired head coach Matt Rhule earlier this month with the team struggling for form, prompting speculation about McCaffrey’s future.

    The Panthers thanked the running-back in a tweet on Thursday, writing: “Thank you, Run CMC.”

    He will return to the Bay Area where he attended college at Stanford, coming runner-up in the Heisman Trophy in 2015.

    McCaffrey may play a minor role for his new team as the 49ers take on the Kansas City Chiefs on Sunday.

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  • What Elizabeth Holmes’ life in prison could look like | CNN Business

    What Elizabeth Holmes’ life in prison could look like | CNN Business

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    CNN
     — 

    Once a Silicon Valley icon and paper billionaire, Elizabeth Holmes will now have to wake every morning at 6 a.m., hold a job paying as little as $0.12 an hour, and share bathing facilities at a prison camp in southern Texas.

    Holmes reported to the Federal Prison Camp in Bryan, Texas, on Tuesday to begin serving out her 11-year sentence after being convicted on multiple charges of defrauding investors while running the now-defunct startup Theranos. Her request to remain free on bail while she appeals her conviction was denied by an appellate court earlier this month.

    Located approximately 100 miles outside of Houston, where Holmes grew up before moving to California to attend Stanford, FPC Bryan is a minimum-security federal prison camp housing more than 600 women offenders.

    Bryan has other notable inmates. It is the same facility where Jennifer Shah, a cast member on Bravo’s “Real Housewives of Salt Lake City,” is serving out her own sentence for her involvement in a telemarketing fraud scheme.

    Holmes herself once graced the covers of magazines, appeared alongside prominent figures like Bill Clinton at conferences and attracted a who’s who of investors for Theranos, which promised to test for a wide range of health concerns using just a few drops of blood. But it all began to unravel after a damning Wall Street Journal investigation in 2015. Holmes is now the rare Silicon Valley founder to be tried for and convicted of fraud.

    Federal prison camps are minimum security institutions with dormitory housing, a relatively low staff-to-inmate ratio, and limited or no perimeter fencing, according to the Federal Bureau of Prisons. These prisons are sometimes nicknamed “Camp Fed” because they’re less restrictive than other institutions.

    But according to Mark MacDougall, a longtime white-collar defense lawyer and former federal prosecutor, the prison won’t be a walk in the park for Holmes.

    “I think people who talk about ‘Camp Fed’ have never actually been inside a federal correctional institution,” MacDougall told CNN. “It’s not a place where people would want to spend time if they could be somewhere else.”

    FPC Bryan will likely be heavily populated with white-collar offenders, according MacDougall. Housing at FPC Bryan typically consists of dormitory-style arrangements featuring a four-bunk cubicle and communal bath facilities, he said.

    “There’s no privacy,” he said.

    Inmates at FPC Bryan are required to maintain a job assignment, according to the prison’s handbook, with hourly wages ranging from $0.12 to $1.15. Holmes will have to wear a uniform of khaki pants and a khaki shirt – a far cry from her black turtleneck days. She also can’t wear jewelry, except for a plain wedding band and a religious medallion without stones, according to the handbook, and the value of these items can’t exceed $100 each.

    MacDougall noted that there’s many volunteer opportunities at Bryan, and it’s very likely that someone with Holmes’ background might find herself teaching.

    “I expect she would be teaching in some fashion,” he said. “That’s a very common occupation for inmates who have some education.” (Holmes dropped out of Stanford at age 19 to pursue Theranos.)

    Holmes, who became a mother of two in the time between her indictment in 2018 and the start of her prison sentence, will also only be able to see her children and other family during visiting hours on weekends and federal holidays at FPC Bryan. Holmes and her family have most recently been living in California.

    As MacDougall put it, “Anybody that suggests that she’s going to be in a pleasant environment or have an easy time of it is kidding themselves.”

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  • Elizabeth Holmes objects to government requesting she pay $250 a month to victims after prison | CNN Business

    Elizabeth Holmes objects to government requesting she pay $250 a month to victims after prison | CNN Business

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    CNN
     — 

    Elizabeth Holmes, the disgraced former Theranos CEO, has “limited financial means” and should not be forced to pay $250 a month to victims of her crimes after she is released from prison, her lawyers argued in a court filing on Monday.

    The move from Holmes’ attorneys comes after federal prosecutors said in a separate filing last week that “clerical errors” had resulted in no payment schedule being set for Holmes’ restitution after she is released from prison. Holmes and former Theranos COO Ramesh “Sunny” Balwani were previously ordered to pay $452 million in restitution to victims of their crimes.

    Holmes reported to prison late last month in Texas to serve out her more than 11-year sentence. She was convicted early last year on multiple charges of defrauding investors while running the failed blood-testing startup Theranos.

    Federal prosecutors asked that once Holmes is on supervised released, criminal monetary penalties should be paid monthly in the amount of $250, or at least 10% of her wages, whichever is greater.

    In the latest filing, Holmes’ attorneys argued “there is no basis in the record for the payment structure in the government’s request,” but did not object to her being asked to start paying $25 per quarter as part of her restitution while she is in prison.

    Holmes, once a paper billionaire, could hold a job at the Federal Prison Camp in Bryan, Texas, with hourly wages ranging from $0.12 to $1.15, according to the prison’s handbook.

    Theranos once claimed to have invented technology that could test for a range of conditions using a few drops of blood. It was valued at some $9 billion at its peak and raised money from a long list of prominent investors. Then it all began to unravel after a damning Wall Street Journal report cast doubt on the company’s claims.

    As part of the original restitution order, some $125 million is owed to media mogul Rupert Murdoch, as well as millions in payments to other Theranos investors.

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  • Elizabeth Holmes could be released from prison two years earlier than expected | CNN Business

    Elizabeth Holmes could be released from prison two years earlier than expected | CNN Business

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    CNN
     — 

    Disgraced former Theranos CEO Elizabeth Holmes could be out of prison nearly two years earlier than expected, according to the projected release date posted by the Bureau of Prisons.

    Holmes reported to a Texas prison camp in late May after being sentenced to 11 years and three months in prison at the end of last year. The Bureau of Prisons online database now reports, however, that Holmes’ expected release date is December 29, 2032 – which would take roughly two years off of her full sentence.

    The discrepancy appears to be due to how the Bureau of Prisons calculates its estimated release date.

    A spokesperson for the Bureau of Prisons told CNN that the agency cannot comment on the conditions of any individual inmate, but said that inmates can earn Good Conduct Time (or GCT) that is calculated into their projected release date. Qualified inmates are currently eligible for up to 54 days of GCT time for each year of the sentence imposed by the court.

    Moreover, inmates have other ways of earning time credits while incarcerated, the spokesperson said, pointing to a range of other factors that could go into calculating the agency’s estimated release date, including an inmate’s participation in various prison programs. These factors that go into calculating an estimated release date are not unique to Holmes’ case, but standard for inmates.

    Holmes is currently serving out her sentence at Federal Prison Camp Bryan, a minimum security federal prison camp that is approximately 100 miles from Houston. Her request to remain free on bail while she fights to overturn her conviction was denied by an appellate court in May.

    Holmes was once an icon in the tech world, serving as a poster child for the limitless ambitions and potential of Silicon Valley. She is now one of the rare tech executives to be serving prison time after being convicted early last year on multiple charges of defrauding investors while running Theranos.

    Theranos was valued at $9 billion at its peak – making Holmes a paper billionaire. The company began to unravel after a Wall Street Journal investigation in 2015 reported that Theranos had only ever performed roughly a dozen of the hundreds of tests it offered using its proprietary technology, and with questionable accuracy. It also came to light that Theranos was relying on third-party manufactured devices from traditional blood testing companies rather than its own technology.

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  • Elizabeth Holmes must report to prison this month while waiting out her appeal, judge rules | CNN Business

    Elizabeth Holmes must report to prison this month while waiting out her appeal, judge rules | CNN Business

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    CNN
     — 

    A judge on Monday denied Elizabeth Holmes’ request to remain free while she appeals her conviction, setting the stage for the disgraced Theranos founder to report to prison later this month.

    In his order, Judge Edward Davila of the Northern District of California said Holmes does not pose a danger to the community or a flight risk, but he cast doubt on her appeal. Even if Homes won her appeal, he said, it is unlikely to result in a reversal, or an order for a new trial, for all of the counts on which she was found guilty.

    Davila previously ordered Holmes to turn herself into custody on April 27, 2023.

    Holmes was sentenced to more than 11 years in prison last November, after she was convicted months earlier on multiple charges of defrauding investors while running the failed blood testing startup Theranos. Attorneys for Holmes did not immediately respond to CNN’s request for comment on the ruling.

    Ramesh “Sunny” Balwani, Holmes’ ex-boyfriend and the former chief operating officer at Theranos, was also found guilty on multiple counts of fraud in a separate trial. He was sentenced to nearly 13 years in prison last December. Balwani’s request to remain out of prison during his appeal was also denied, and he has been ordered by Davila to surrender to prison on April 20.

    Once valued at $9 billion, Theranos attracted top investors and retail partners with claims that it had developed technology to test for a wide range of conditions using just a few drops of blood. The company began to unravel after a Wall Street Journal investigation in 2015 reported that Theranos had only ever performed roughly a dozen of the hundreds of tests it offered using its proprietary technology, and with questionable accuracy.

    Holmes’ trial was initially delayed multiple times, due to the onset of the coronavirus pandemic and then because of her pregnancy. Following her sentencing in November, Holmes sought to delay the start of her prison term after giving birth to her second child.

    While Davila denied Holmes represented a flight risk, he also addressed the fact that she had previously booked a one-way ticket to Mexico in January 2022.

    “Booking international travel plans for a criminal defendant in anticipation of a complete defense victory is a bold move, and the failure to promptly cancel those plans after a guilty verdict is a perilously careless oversight,” Davila wrote in the court filing.

    Holmes’ attorneys had previously claimed that Holmes had hoped the verdict would be different when booking the travel plans and that she wanted to make this trip to attend the wedding of friends in Mexico. Davila wrote in court documents that the court accepts Holmes’ “representation that the oneway flight ticket—while ill-advised—was not an attempt to flee the country.”

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  • Elizabeth Holmes delays start of prison sentence with last-minute appeal | CNN Business

    Elizabeth Holmes delays start of prison sentence with last-minute appeal | CNN Business

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    New York
    CNN
     — 

    Elizabeth Holmes won’t be starting her 11-year prison sentence just yet.

    The disgraced Theranos founder was previously expected to report to prison on Thursday, but she will remain free a little longer while the court considers a last-minute appeal, according to a filing Tuesday night.

    Holmes was sentenced last November after she was convicted months earlier on multiple charges of defrauding investors while running the now-defunct blood testing startup. Earlier this month, her request to remain free while she appeals her conviction was denied by a judge, setting her up to report to prison on April 27.

    On Tuesday, however, Holmes’ legal team filed an appeal of the judge’s decision. As a result, Holmes can remain free on bail while the latest appeal is considered by the court, as per the court’s rules.

    Holmes dropped out of Stanford at the age of 19 to focus full-time on Theranos, the health tech startup which claimed to have invented technology that could accurately test for a range of conditions using just a few drops of blood. Theranos raised $945 million from an impressive list of investors and was valued at some $9 billion at its peak – making Holmes a paper billionaire.

    Her company began to unravel after a Wall Street Journal investigation in 2015 reported that Theranos had only ever performed roughly a dozen of the hundreds of tests it offered using its proprietary technology, and with questionable accuracy. It also came to light that Theranos was relying on third-party manufactured devices from traditional blood testing companies rather than its own technology.

    Holmes’ ex-boyfriend and former COO Ramesh “Sunny” Balwani was indicted alongside Holmes and convicted of fraud in a separate trial. Like Holmes, Balwani’s legal team delayed the start of his prison sentence by roughly a month with an appeal.

    Balwani reported to prison last week to serve out his nearly 13-year sentence.

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  • Elizabeth Holmes reports to prison | CNN Business

    Elizabeth Holmes reports to prison | CNN Business

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    CNN
     — 

    Elizabeth Holmes reported to prison on Tuesday, capping off a stunning downfall for the disgraced founder of failed blood testing startup Theranos.

    Holmes was sentenced to more than 11 years in prison last November, after she was convicted months earlier on multiple charges of defrauding investors while running the now-defunct startup.

    Her request to remain free on bail while she fights to overturn her conviction was denied by an appellate court earlier this month. Judge Edward Davila, who presided over her trial, ordered Holmes to turn herself in to the Bureau of Prisons by May 30 to begin serving her sentence.

    Holmes arrived Tuesday at Federal Prison Camp Bryan in southern Texas, a minimum security federal prison camp that is approximately 100 miles from Houston, where she grew up before moving to California to attend Stanford.

    “We can confirm Elizabeth Holmes has arrived at the Federal Prison Camp (FPC) Bryan in Bryan, Texas, and is in the custody of the Federal Bureau of Prisons,” a spokesperson for the Bureau of Prisons said in a statement provided to CNN.

    Her ex-boyfriend and former Theranos COO Ramesh “Sunny” Balwani was also convicted of fraud, and reported to prison in California last month to begin serving out his sentence.

    Holmes was once an icon in the tech world, serving as a posterchild for the limitless ambitions and potential of Silicon Valley. Now, she and Balwani are the rare tech executives tried for, and convicted on, fraud charges.

    Holmes dropped out of Stanford at the age of 19 to focus full-time on Theranos, a startup that claimed to have invented technology that could accurately test for a range of conditions using just a few drops of blood. Theranos raised $945 million from an impressive list of investors and was valued at some $9 billion at its peak – making Holmes a paper billionaire. She graced magazine covers and engaged in public speaking events wearing a black turtleneck that invited comparisons to the late Apple CEO Steve Jobs.

    Her company began to unravel after a Wall Street Journal investigation in 2015 reported that Theranos had only ever performed roughly a dozen of the hundreds of tests it offered using its proprietary technology, and with questionable accuracy. It also came to light that Theranos was relying on third-party manufactured devices from traditional blood testing companies rather than its own technology.

    Theranos ultimately dissolved in September 2018.

    Dawn breaks at the Federal Prison Camp where Elizabeth Holmes, the former founder and CEO of Theranos, is expected to arrive to begin her 11 year sentence for fraud relating to the defunct company Tuesday, May 30, 2023, in Bryan, Texas.

    Holmes and Balwani were first indicted together nearly five years ago on the same 12 criminal charges. Their trials were severed after Holmes indicated she intended to accuse Balwani of sexually, emotionally and psychologically abusing her throughout their decade-long relationship, which coincided with her time running the company. (Balwani’s attorneys have denied her claims.)

    This month, Davila ordered Holmes and Balwani to pay restitution of roughly $452 million to victims of their crimes.

    Before her sentencing was announced in November, a tearful Holmes spoke to the court in San Jose, California.

    “I loved Theranos. It was my life’s work,” she said. “The people I tried to get involved with Theranos were the people I loved and respected the most. I am devastated by my failings.”

    She went on to apologize to the employees, investors and patients of Theranos.

    “I’m so, so sorry. I gave everything I had to build our company and to save our company,” she said. “I regret my failings with every cell in my body.”

    – CNN’s Brad Parks contributed to this report.

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  • YourEncore® Joins AARP® Employer Pledge Program

    YourEncore® Joins AARP® Employer Pledge Program

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    National effort helps employers solve staffing challenges, directs job seekers to employers that value and hire experience

    Press Release



    updated: Jun 12, 2017

    ​​​​​​​​​​YourEncore, a leading provider of world-class expertise for flexible resourcing and consulting engagements to life sciences and consumer goods companies, has joined more than 450 organizations in signing the AARP Employer Pledge, confirming their commitment to hiring across the age spectrum and leveraging the value that experienced workers bring to companies of all sizes.

    “YourEncore was founded on the core principle that experience matters,” said Mike Lewis, Chief Sales & Marketing Officer at YourEncore. “Our mission is to put experience to work. We offer clients the opportunity to tap into the most accomplished and experienced community of experts in the world, and we offer our talent community, or YourEncore Experts as we call them, the opportunity to use their experience to make a lasting difference. We are excited to join with AARP in its mission to drive awareness of the wisdom, experience, and technical skill of accomplished business professionals.”

    “YourEncore was founded on the core principle that experience matters. We are excited to join with AARP in its mission to drive awareness of the wisdom, experience, and technical skill of accomplished business professionals. We’re passionate about creating the workforce of the future…one that is ageless, inspires and engages talent, and accelerates business performance. We look forward to working with AARP on this all-important journey.”

    Mike Lewis, YourEncore Chief Sales & Marketing Officer

    Employers are facing a chasm of wisdom, experience, and absolute talent supply that places achievement of their business objectives at risk. Over 10,000 Baby Boomers retire every day. While Millennials currently provide the workforce with a large infusion of talent, their numbers alone are still not enough to stem the tide of departing Boomers1. This talent gap cannot be closed with traditional employment models. Given the seismic shifts taking place in today’s workforce, companies need to think differently about how they utilize talent, and individuals need to think differently about how they approach work. YourEncore is uniquely positioned to provide both groups with the solutions they need to successfully navigate and take advantage of this perfect storm that is today’s economy.

    YourEncore combines cutting-edge technology and high-touch personal engagement to build robust, vibrant talent communities, match talent to business requirements, and create tailored talent solutions that allow clients to transform and grow and Experts to realize their personal and professional goals.

    Although some Boomers are stepping away from traditional full-time, career-focused employment, many want to continue working, for a host of reasons from social to professional to financial2. YourEncore is a leader in mobilizing this “encore workforce” and has helped thousands of Experts build successful consulting careers through rewarding project work and professional development.

    For clients, YourEncore deploys world class expertise from their Expert Network to solve complex problems, support critical initiatives, and fill capability and capacity gaps. Experts are hand-picked and matched for subject matter expertise and business acumen. They are alumni from some of the best companies in the world, average over 25 years of experience, and the majority hold advanced degrees. The power of that experience – which the AARP Employer Pledge Program is designed to elevate – is the impetus behind the founding and on-going growth of YourEncore.

    “We’re passionate about creating the workforce of the future…one that is ageless, inspires and engages talent, and accelerates business performance,” said Lewis. “We look forward to working with AARP on this all-important journey.”

    About YourEncore®: YourEncore is a leading provider of proven expertise, delivering flexible resourcing and consulting services to the biopharma, medical devices and diagnostics, and consumer goods industries. YourEncore mobilizes the wisdom and knowledge of highly experienced, immediately effective Experts to help companies outthink, outpace, and outperform. Based in Indianapolis, IN, with offices in Cincinnati, OH and Princeton, NJ, YourEncore was named a “100 Most Brilliant Company” by Entrepreneur Magazine. For more information, visit yourencore.com and follow us on Facebook @YourEncore, Twitter @YourEncoreInc, and LinkedIn.

    1https://www.conference-board.org/laborshortages/

    2https://www.transamericacenter.org/docs/default-source/retirement-survey-of-workers/tcrs2016_sr_perspectives_on_retirement_baby_boomers_genx_millennials.pdf

    Media Contacts:

    Mike Lewis 609.216.7903 mike.lewis@yourencore.com

    Nancy Reilly 513.609.4516 nancy.reilly@yourencore.com

    Source: YourEncore, Inc.

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